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The aim of the present work is to analyze the role of the unconscious in the establishment of subjectivity in Hegel’s philosophy of subjective spirit. The project is divided into three chapters and aims to re-evaluate a part of the Hegelian system, the philosophy of subjective spirit, which has only recently attracted the interest of the Hegel-Researchers. The first chapter is dedicated to anthropology, which makes up the first part of the philosophy of subjective spirit, and acts as a link between philosophy of nature and philosophy of the spirit of the Encyclopedia of Philosophical Sciences. In Anthropology, Hegel sets out his doctrine of the soul. The role of the unconscious emerges first of all in the sentient soul in relation to the various forms of the magical relationship (magnetic somnambulism, animal magnetism, mesmerism), to dreams and mental illness. In the same chapter we analyze the difference between romantic medicine and empirical medicine in accordance with Hegel’s contemporary medical nosology, in order to establish an intermediate position. The second chapter deals with the dissolution of the false problem of soul-body dualism exposed by Hegel at § 389. As a result the idea of an embodied mind towards naturalism of second nature develops. This process is fully realized, through habit and the acquisition of a second nature, with the birth of the ego in the real soul. In the third chapter the role of the unconscious in the field of psychology is tackled, on the one hand in relation to the theoretical spirit, and on the other, in relation to the practical spirit. Hegel introduces expressions like ‘Night pit’ and ‘dormant images’ and uses terms like bewusstlos to emphasize the importance of the unconscious in this third part of the subjective Spirit. In particular, the role of the unconscious is played on two levels, at the epistemological level in the theoretical Spirit and on the practical level or rather from the point of view of acting in the practical Spirit. With regard to the theoretical spirit, the unconscious emerges on a representative level. A similar situation occurs in the practical spirit on the level of impulses and arbitrariness, creating a dichotomy in terms of action. Although this part of the subjective spirit still represents a preamble of action, the Psychology of Hegel presents at the same time a ‘fundamental ethic’.

The aim of this study was to compare the bioavailab ility and determine the bioequivalence of one test formul ation (citalopram 20 mg oral tablet) with its correspondi ng list reference-drug formulation in Mexico. A single dose, randomized, open-label, 2-period cro ss- over, post-marketing study with a 2-weeks washout p e- riod between doses was conducted. Blood samples wer e drawn at baseline, 0.5, 1.0, 2.0, 3.0, 4.0, 5.0, 6. 0, 7.0, 8.0, 10.0, 12.0, 24.0, 48.0, 72.0, 96.0 y 120.0 hours af ter dos- ing. Citalopram plasma levels were determined using HPLC assay method. A total of 24 subjects were enrolled in the study. The bioequivalence test drug values were C max of 26.37 ng/ mL, t max of 3.76 h, AUC 0-t of 613.84 h.ng/mL, AUC 0- ∞ of 879.65 h. ng/mL, and reference drug values of C max of 25.50 ng/mL, t max of 3.96 h AUC 0-t of 596.65 h. ng/mL, AUC 0- ∞ of 982.38 h. ng/mL. No period or sequence effect w as observed. In this study in healthy Mexican adult subjects, a single dose of citalopram 20 mg of the test formulation wa s found to be bioequivalent to the corresponding reference formu- lation according to the regulatory definition of bioequivalence based on the rate and extent of abso rp- tion. Both formulations were generally well tolerat ed.