AGuIX nanoparticle-nanobody bioconjugates to target immune checkpoint receptors

Authors :: Carmès, Léna
Bort, Guillaume
Lux, François
Seban, Léa
Rocchi, Paul
Muradova, Zeinaf
Hagège, Agnès
Heinrich-Balard, Laurence
Delolme, Frédéric
Gueguen-Chaignon, Virginie
Truillet, Charles
Crowley, Stephanie
Bello, Elisa
Doussineau, Tristan
Dougan, Michael
Tillement, Olivier
Schoenfeld, Jonathan
Brown, Needa
Berbeco, Ross
Publication Year :: 2024
Abstract: Comparison of click chemistry and sortagging grafting strategies for functionalizing AGuIX nanoparticles with nanobodies to develop a tri-functional technology combining MRI imaging, radiotherapy, and immunotherapy by inhibiting immune checkpoints.<br />Comment: Nanoscale, 2024

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