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2. Toward Precision Medicine for Neurological and Neuropsychiatric Disorders.

Author

Gibbs RM, Lipnick S, Bateman JW, Chen L, Cousins HC, Hubbard EG, Jowett G, LaPointe DS, McGredy MJ, Odonkor MN, Repetti G, Thomas E, and Rubin LL

Subjects
Humans, Mental Disorders genetics, Mental Disorders pathology, Nervous System Diseases genetics, Nervous System Diseases pathology, Mental Disorders therapy, Nervous System Diseases therapy, Precision Medicine, Stem Cell Transplantation, Stem Cells cytology
Abstract

The genetic complexity, clinical variability, and inaccessibility of affected tissue in neurodegenerative and neuropsychiatric disorders have largely prevented the development of effective disease-modifying therapeutics. A precision medicine approach that integrates genomics, deep clinical phenotyping, and patient stem cell models may facilitate identification of underlying biological drivers and targeted drug development., (Copyright © 2018 Elsevier Inc. All rights reserved.)

Published
2018
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