1. Therapeutic and regenerative potential of different sources of mesenchymal stem cells for cardiovascular diseases.
- Author
-
ALZGHOUL, YARA, BANI ISSA, HALA J., SANAJLEH, AHMAD K., ALABDUH, TAQWA, RABABAH, FATIMAH, AL-SHDAIFAT, MAHA, ABU-EL-RUB, EJLAL, ALMAHASNEH, FATIMAH, KHASAWNEH, RAMADA R., ALZU'BI, AYMAN, and MAGABLEH, HUTHAIFA
- Subjects
- *
MESENCHYMAL stem cells , *CARDIOVASCULAR diseases , *HEART function tests , *IMMUNOREGULATION , *CELL differentiation - Abstract
Mesenchymal stemcells (MSCs) are ideal candidates for treatingmany cardiovascular diseases. MSCs can modify the internal cardiac microenvironment to facilitate their immunomodulatory and differentiation abilities, which are essential to restore heart function. MSCs can be easily isolated from different sources, including bone marrow, adipose tissues, umbilical cord, and dental pulp. MSCs from various sources differ in their regenerative and therapeutic abilities for cardiovascular disorders. In this review, we will summarize the therapeutic potential of each MSC source for heart diseases and highlight the possible molecular mechanisms of each source to restore cardiac function. [ABSTRACT FROM AUTHOR]
- Published
- 2024
- Full Text
- View/download PDF