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Therapeutic and regenerative potential of different sources of mesenchymal stem cells for cardiovascular diseases.

Authors :
ALZGHOUL, YARA
BANI ISSA, HALA J.
SANAJLEH, AHMAD K.
ALABDUH, TAQWA
RABABAH, FATIMAH
AL-SHDAIFAT, MAHA
ABU-EL-RUB, EJLAL
ALMAHASNEH, FATIMAH
KHASAWNEH, RAMADA R.
ALZU'BI, AYMAN
MAGABLEH, HUTHAIFA
Source :
Biocell. 2024, Vol. 48 Issue 4, p559-569. 11p.
Publication Year :
2024

Abstract

Mesenchymal stemcells (MSCs) are ideal candidates for treatingmany cardiovascular diseases. MSCs can modify the internal cardiac microenvironment to facilitate their immunomodulatory and differentiation abilities, which are essential to restore heart function. MSCs can be easily isolated from different sources, including bone marrow, adipose tissues, umbilical cord, and dental pulp. MSCs from various sources differ in their regenerative and therapeutic abilities for cardiovascular disorders. In this review, we will summarize the therapeutic potential of each MSC source for heart diseases and highlight the possible molecular mechanisms of each source to restore cardiac function. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
03279545
Volume :
48
Issue :
4
Database :
Academic Search Index
Journal :
Biocell
Publication Type :
Academic Journal
Accession number :
176738059
Full Text :
https://doi.org/10.32604/biocell.2024.048056