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11 results on '"Astrid Münnich"'

1. A 1D imaging soft X-ray spectrometer for the small quantum systems instrument at the European XFEL

Author

Marcus Agåker, Johan Söderström, Thomas M. Baumann, Carl-Johan Englund, Ludvig Kjellsson, Rebecca Boll, Alberto De Fanis, Simon Dold, Tommaso Mazza, Jacobo Montaño, Astrid Münnich, Terence Mullins, Yevheniy Ovcharenko, Nils Rennhack, Philipp Schmidt, Björn Senfftleben, Monica Turcato, Sergey Usenko, Michael Meyer, Joseph Nordgren, and Jan-Erik Rubensson

Subjects
soft x-ray scattering, resonant inelastic x-ray scattering, rixs, soft x-ray spectrometers, x-ray free-electron lasers, xfel, Nuclear and particle physics. Atomic energy. Radioactivity, QC770-798, Crystallography, QD901-999
Abstract

A 1D imaging soft X-ray spectrometer installed on the small quantum systems (SQS) scientific instrument of the European XFEL is described. It uses movable cylindrical constant-line-spacing gratings in the Rowland configuration for energy dispersion in the vertical plane, and Wolter optics for simultaneous 1D imaging of the source in the horizontal plane. The soft X-ray fluorescence spectro-imaging capability will be exploited in pump–probe measurements and in investigations of propagation effects and other nonlinear phenomena.

Published
2024
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2. Megahertz pulse trains enable multi-hit serial femtosecond crystallography experiments at X-ray free electron lasers

Author

Susannah Holmes, Henry J. Kirkwood, Richard Bean, Klaus Giewekemeyer, Andrew V. Martin, Marjan Hadian-Jazi, Max O. Wiedorn, Dominik Oberthür, Hugh Marman, Luigi Adriano, Nasser Al-Qudami, Saša Bajt, Imrich Barák, Sadia Bari, Johan Bielecki, Sandor Brockhauser, Mathew A. Coleman, Francisco Cruz-Mazo, Cyril Danilevski, Katerina Dörner, Alfonso M. Gañán-Calvo, Rita Graceffa, Hans Fanghor, Michael Heymann, Matthias Frank, Alexander Kaukher, Yoonhee Kim, Bostjan Kobe, Juraj Knoška, Torsten Laurus, Romain Letrun, Luis Maia, Marc Messerschmidt, Markus Metz, Thomas Michelat, Grant Mills, Serguei Molodtsov, Diana C. F. Monteiro, Andrew J. Morgan, Astrid Münnich, Gisel E. Peña Murillo, Gianpietro Previtali, Adam Round, Tokushi Sato, Robin Schubert, Joachim Schulz, Megan Shelby, Carolin Seuring, Jonas A. Sellberg, Marcin Sikorski, Alessandro Silenzi, Stephan Stern, Jola Sztuk-Dambietz, Janusz Szuba, Martin Trebbin, Patrick Vagovic, Thomas Ve, Britta Weinhausen, Krzysztof Wrona, Paul Lourdu Xavier, Chen Xu, Oleksandr Yefanov, Keith A. Nugent, Henry N. Chapman, Adrian P. Mancuso, Anton Barty, Brian Abbey, and Connie Darmanin

Subjects
Science
Abstract

Free-electron lasers are capable of high repetition rates and it is assumed that protein crystals often do not survive the first X-ray pulse. Here the authors address these issues with a demonstration of multi-hit serial crystallography in which multiple FEL pulses interact with the sample without destroying it.

Published
2022
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3. Megahertz serial crystallography

Author

Max O. Wiedorn, Dominik Oberthür, Richard Bean, Robin Schubert, Nadine Werner, Brian Abbey, Martin Aepfelbacher, Luigi Adriano, Aschkan Allahgholi, Nasser Al-Qudami, Jakob Andreasson, Steve Aplin, Salah Awel, Kartik Ayyer, Saša Bajt, Imrich Barák, Sadia Bari, Johan Bielecki, Sabine Botha, Djelloul Boukhelef, Wolfgang Brehm, Sandor Brockhauser, Igor Cheviakov, Matthew A. Coleman, Francisco Cruz-Mazo, Cyril Danilevski, Connie Darmanin, R. Bruce Doak, Martin Domaracky, Katerina Dörner, Yang Du, Hans Fangohr, Holger Fleckenstein, Matthias Frank, Petra Fromme, Alfonso M. Gañán-Calvo, Yaroslav Gevorkov, Klaus Giewekemeyer, Helen Mary Ginn, Heinz Graafsma, Rita Graceffa, Dominic Greiffenberg, Lars Gumprecht, Peter Göttlicher, Janos Hajdu, Steffen Hauf, Michael Heymann, Susannah Holmes, Daniel A. Horke, Mark S. Hunter, Siegfried Imlau, Alexander Kaukher, Yoonhee Kim, Alexander Klyuev, Juraj Knoška, Bostjan Kobe, Manuela Kuhn, Christopher Kupitz, Jochen Küpper, Janine Mia Lahey-Rudolph, Torsten Laurus, Karoline Le Cong, Romain Letrun, P. Lourdu Xavier, Luis Maia, Filipe R. N. C. Maia, Valerio Mariani, Marc Messerschmidt, Markus Metz, Davide Mezza, Thomas Michelat, Grant Mills, Diana C. F. Monteiro, Andrew Morgan, Kerstin Mühlig, Anna Munke, Astrid Münnich, Julia Nette, Keith A. Nugent, Theresa Nuguid, Allen M. Orville, Suraj Pandey, Gisel Pena, Pablo Villanueva-Perez, Jennifer Poehlsen, Gianpietro Previtali, Lars Redecke, Winnie Maria Riekehr, Holger Rohde, Adam Round, Tatiana Safenreiter, Iosifina Sarrou, Tokushi Sato, Marius Schmidt, Bernd Schmitt, Robert Schönherr, Joachim Schulz, Jonas A. Sellberg, M. Marvin Seibert, Carolin Seuring, Megan L. Shelby, Robert L. Shoeman, Marcin Sikorski, Alessandro Silenzi, Claudiu A. Stan, Xintian Shi, Stephan Stern, Jola Sztuk-Dambietz, Janusz Szuba, Aleksandra Tolstikova, Martin Trebbin, Ulrich Trunk, Patrik Vagovic, Thomas Ve, Britta Weinhausen, Thomas A. White, Krzysztof Wrona, Chen Xu, Oleksandr Yefanov, Nadia Zatsepin, Jiaguo Zhang, Markus Perbandt, Adrian P. Mancuso, Christian Betzel, Henry Chapman, and Anton Barty

Subjects
Science
Abstract

The new European X-Ray Free-Electron Laser (EuXFEL) is the first XFEL that generates X-ray pulses with a megahertz inter-pulse spacing. Here the authors demonstrate that high-quality and damage-free protein structures can be obtained with the currently available 1.1 MHz repetition rate pulses using lysozyme as a test case and furthermore present a β-lactamase structure.

Published
2018
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4. Megahertz data collection from protein microcrystals at an X-ray free-electron laser

Author

Marie Luise Grünbein, Johan Bielecki, Alexander Gorel, Miriam Stricker, Richard Bean, Marco Cammarata, Katerina Dörner, Lars Fröhlich, Elisabeth Hartmann, Steffen Hauf, Mario Hilpert, Yoonhee Kim, Marco Kloos, Romain Letrun, Marc Messerschmidt, Grant Mills, Gabriela Nass Kovacs, Marco Ramilli, Christopher M. Roome, Tokushi Sato, Matthias Scholz, Michel Sliwa, Jolanta Sztuk-Dambietz, Martin Weik, Britta Weinhausen, Nasser Al-Qudami, Djelloul Boukhelef, Sandor Brockhauser, Wajid Ehsan, Moritz Emons, Sergey Esenov, Hans Fangohr, Alexander Kaukher, Thomas Kluyver, Max Lederer, Luis Maia, Maurizio Manetti, Thomas Michelat, Astrid Münnich, Florent Pallas, Guido Palmer, Gianpietro Previtali, Natascha Raab, Alessandro Silenzi, Janusz Szuba, Sandhya Venkatesan, Krzysztof Wrona, Jun Zhu, R. Bruce Doak, Robert L. Shoeman, Lutz Foucar, Jacques-Philippe Colletier, Adrian P. Mancuso, Thomas R. M. Barends, Claudiu A. Stan, and Ilme Schlichting

Subjects
Science
Abstract

The European X-ray free-electron laser (EuXFEL) in Hamburg is the first megahertz (MHz) repetition rate XFEL. Here the authors use lysozyme crystals and microcrystals from jack bean proteins and demonstrate that damage-free high quality data can be collected at a MHz repetition rate.

Published
2018
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5. The 1-Megapixel pnCCD detector for the Small Quantum Systems Instrument at the European XFEL: system and operation aspects

Author

Hazem Yousef, Karim Ahmed, Astrid Münnich, Tonn Rüter, Kiana Setoodehnia, Cyril Danilevski, Steffen Hauf, Rico Mayro P. Tanyag, Rüdiger Schmitt, Michael Meyer, Lothar Strüder, Marko Ž. Ekmedžić, Daniela Rupp, Jacobo Montaño, P. Gessler, Dieter Schlosser, Anatoli Ulmer, Peter Holl, Markus Kuster, Robert Hartmann, Nils Rennhack, Y. Ovcharenko, Bruno Fernandes, and Kai Erik Ballak

Subjects
X-ray detector, Nuclear and High Energy Physics, Physics - Instrumentation and Detectors, Photon, X-ray CCD, Computer science, FOS: Physical sciences, 02 engineering and technology, 01 natural sciences, Dot pitch, free-electron laser, 0103 physical sciences, Quantum system, Electronic engineering, Physics - Atomic and Molecular Clusters, 010306 general physics, Instrumentation, photon detection, Radiation, Detector, Free-electron laser, Beamlines, Instrumentation and Detectors (physics.ins-det), 021001 nanoscience & nanotechnology, Coherent diffraction imaging, pnCCD, Charge-coupled device, Atomic and Molecular Clusters (physics.atm-clus), 0210 nano-technology
Abstract

The X-ray free-electron lasers that became available during the last decade, like the European XFEL (EuXFEL), place high demands on their instrumentation. Especially at low photon energies below $1\,\text{keV}$, detectors with high sensitivity, and consequently low noise and high quantum efficiency, are required to enable facility users to fully exploit the scientific potential of the photon source. A 1-Megapixel pnCCD detector with a $1024\times 1024$ pixel format has been installed and commissioned for imaging applications at the Nano-Sized Quantum System (NQS) station of the Small Quantum System (SQS) instrument at EuXFEL. The instrument is currently operating in the energy range between $0.5$ and $3\,\text{keV}$ and the NQS station is designed for investigations of the interaction of intense FEL pulses with clusters, nano-particles and small bio-molecules, by combining photo-ion and photo-electron spectroscopy with coherent diffraction imaging techniques. The core of the imaging detector is a pn-type charge coupled device (pnCCD) with a pixel pitch of $75\,\mu\text{m}\times 75\,\mu\text{m}$. Depending on the experimental scenario, the pnCCD enables imaging of single photons thanks to its very low electronic noise of $3$e$^-$ and high quantum efficiency. Here we present an overview on the EuXFEL pnCCD detector and the results from the commissioning and first user operation at the SQS experiment in June 2019. The detailed descriptions of the detector design and capabilities, its implementation at EuXFEL both mechanically and from the controls side as well as important data correction steps aim to provide useful background for users planning and analyzing experiments at EuXFEL and may serve as a benchmark for comparing and planning future endstations at other FELs., Comment: 10 pages, 10 figures, submitted to the Journal of Synchrotron Radiation

Published
2021

6. MHz data collection of a microcrystalline mixture of different jack bean proteins

Author

Gabriela Nass Kovacs, Djelloul Boukhelef, Alexander Kaukher, Sandhya Venkatesan, Astrid Münnich, Michel Sliwa, Nasser Al-Qudami, Jolanta Sztuk-Dambietz, Sergey Esenov, Lutz Foucar, A. Gorel, Krzysztof Wrona, Janusz Szuba, Maurizio Manetti, Thomas Kluyver, Marco Cammarata, Jun Zhu, Johan Bielecki, Matthias Scholz, Marc Messerschmidt, Richard Bean, Gianpietro Previtali, Thomas Michelat, Sandor Brockhauser, Natascha Raab, M. Hilpert, Thomas R. M. Barends, Alessandro Silenzi, Katerina Dörner, Moritz Emons, Yoonhee Kim, Grant Mills, C.M. Roome, Luis Maia, Max Lederer, Jacques-Philippe Colletier, Wajid Ehsan, Steffen Hauf, Britta Weinhausen, Marco Ramilli, Marco Kloos, Elisabeth Hartmann, Romain Letrun, Claudiu A. Stan, Florent Pallas, Marie Luise Grünbein, R. Bruce Doak, Martin Weik, Lars Fröhlich, M. Stricker, Robert L. Shoeman, Guido Palmer, Tokushi Sato, Hans Fangohr, Ilme Schlichting, Adrian P. Mancuso, European XFEL GmbH (XFEL), European XFEL GmbH, Max Planck Institute for Medical Research [Heidelberg], Max-Planck-Gesellschaft, Institut de Physique de Rennes (IPR), Université de Rennes (UR)-Centre National de la Recherche Scientifique (CNRS), Elettra Sincrotrone Trieste, National Science Foundation [Arlington] (NSF), Alma Mater Studiorum Università di Bologna [Bologna] (UNIBO), KEK (High energy accelerator research organization), TOPTICA Photonics AG, Laboratoire Avancé de Spectroscopie pour les Intéractions la Réactivité et l'Environnement - UMR 8516 (LASIRE), Institut de Chimie du CNRS (INC)-Université de Lille-Centre National de la Recherche Scientifique (CNRS), Institut de biologie structurale (IBS - UMR 5075 ), Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes [2016-2019] (UGA [2016-2019])-Institut de Recherche Interdisciplinaire de Grenoble (IRIG), Direction de Recherche Fondamentale (CEA) (DRF (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Direction de Recherche Fondamentale (CEA) (DRF (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA), European Synchrotron Radiation Facility (ESRF), European Molecular Biology Laboratory [Grenoble] (EMBL), Institut de Microélectronique, Electromagnétisme et Photonique (IMEP), Université Joseph Fourier - Grenoble 1 (UJF)-Institut National Polytechnique de Grenoble (INPG)-Centre National de la Recherche Scientifique (CNRS), NINGBO UNIVERSITY, Ningbo University (NBU), Department of Biomolecular Mechanisms, Max-Planck-Gesellschaft-Max-Planck-Gesellschaft, Rutgers University [Newark], Rutgers University System (Rutgers), Deutsches Elektronen-Synchrotron, ANR-17-CE11-0018-01, Agence Nationale de la Recherche, European XFEL, ANR Grant, European XFEL - travel funding provided by the International Synchrotron Access Program (ISAP) managed by the Australian Synchrotron, part of ANSTO, and funded by the Australian Government, ANR Grant (BioXFEL) CEA, CNRS, Universit&amp, x00E9, Grenoble Alpes, startup funds from Rutgers University Newark, ANR-17-CE11-0018,X-in-vivo,Cristallisation in vivo: une nouvelle stratégie pour étudier la structure et la dynamique des protéines dans les lasers à électrons libres et les synchrotrons.(2017), Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Centre National de la Recherche Scientifique (CNRS), Institut de Chimie du CNRS (INC)-Université de Lille-Centre National de la Recherche Scientifique (CNRS)-Centrale Lille Institut (CLIL), Université Grenoble Alpes [2016-2019] (UGA [2016-2019])-Institut de Recherche Interdisciplinaire de Grenoble (IRIG), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Centre National de la Recherche Scientifique (CNRS), and Centre National de la Recherche Scientifique (CNRS)-Institut National Polytechnique de Grenoble (INPG)-Université Joseph Fourier - Grenoble 1 (UJF)

Subjects
Statistics and Probability, Data Descriptor, 010504 meteorology & atmospheric sciences, Computer science, Library and Information Sciences, Crystallography, X-Ray, 01 natural sciences, Education, law.invention, 03 medical and health sciences, Optics, law, Concanavalin A, [CHIM]Chemical Sciences, lcsh:Science, ComputingMilieux_MISCELLANEOUS, 030304 developmental biology, 0105 earth and related environmental sciences, Plant Proteins, [PHYS]Physics [physics], 0303 health sciences, Data collection, business.industry, Nanocrystallography, Detector, Proteins, Frame rate, Laser, Sample (graphics), Urease, Computer Science Applications, Data set, Microcrystalline, Femtosecond, Enzyme mechanisms, lcsh:Q, ddc:500, Statistics, Probability and Uncertainty, business, Crystallization, Information Systems
Abstract

Scientific data 6(1), 18 (2019). doi:10.1038/s41597-019-0010-0, We provide a detailed description of a serial femtosecond crystallography (SFX) dataset collected at the European X-ray free-electron laser facility (EuXFEL). The EuXFEL is the first high repetition rate XFEL delivering MHz X-ray pulse trains at 10 Hz. The short spacing (, Published by Nature Publ. Group, London

Published
2019

7. The Karabo distributed control system

Author

Steffen Hauf, John Wiggins, Gero Flucke, Manuela Kuhn, Daniel Fulla Marsa, Leonce Mekinda, E. Kamil, Sandor Brockhauser, Alessandro Silenzi, Thomas Kluyver, Wajid Ehsan, Yury Kirienko, Cyril Danilevsky, Chen Xu, Valerio Mariani, Valerii Bondar, Gabriele Giovanetti, Hugo Santos, David Hickin, R. Fabbri, Astrid Münnich, Luis Maia, C. Youngman, Anna Padee, Jun Zhu, Steve Aplin, Krzysztof Wrona, Djelloul Boukhelef, Martin Bergemann, Hans Fangohr, Marijan Beg, D. Mamchyk, Thomas Michelat, Andrea Parenti, T. Jarosiewicz, Martin Teichmann, Kerstin Weger, Dmitry Khakhulin, Anna Klimovskaia, Dennis Göries, Sergey Essenov, and Burkhard Heisen

Subjects
0303 health sciences, Nuclear and High Energy Physics, Configuration management, Radiation, Situation awareness, business.industry, Computer science, Interface (computing), Distributed computing, 030303 biophysics, Access control, 010403 inorganic & nuclear chemistry, 01 natural sciences, 0104 chemical sciences, 03 medical and health sciences, Data acquisition, SCADA, Control system, ddc:550, business, Distributed control system, Instrumentation
Abstract

Journal of synchrotron radiation 26(5), 1448 - 1461 (2019). doi:10.1107/S1600577519006696, The Karabo distributed control system has been developed to address the challenging requirements of the European X-ray Free Electron Laser facility, including complex and custom-made hardware, high data rates and volumes, and close integration of data analysis for distributed processing and rapid feedback. Karabo is a pluggable, distributed application management system forming a supervisory control and data acquisition environment as part of a distributed control system. Karabo provides integrated control of hardware, monitoring, data acquisition and data analysis on distributed hardware, allowing rapid control feedback based on complex algorithms. Services exist for access control, data logging, configuration management and situational awareness through alarm indicators. The flexible framework enables quick response to the changing requirements in control and analysis, and provides an efficient environment for development, and a single interface to make all changes immediately available to operators and experimentalists., Published by Wiley-Blackwell, [S.l.]

Published
2019

8. Megahertz Data Collection from Protein Microcrystals at an X-Ray Free-Electron Laser

Author

Florent Pallas, Alexander Kaukher, Martin Weik, Richard Bean, Thomas Michelat, Nasser Al-Qudami, Natascha Raab, Guido Palmer, Yoonhee Kim, Grant Mills, M. Hilpert, Gianpietro Previtali, M. Stricker, Lars Fröhlich, Claudiu A. Stan, Tokushi Sato, Maurizio Manetti, Sergey Esenov, Gabriela Nass Kovacs, Thomas R. M. Barends, Katerina Dörner, Matthias Scholz, Marie Luise Grünbein, Jolanta Sztuk-Dambietz, Elisabeth Hartmann, Steffen Hauf, Robert L. Shoeman, A. Gorel, Britta Weinhausen, Janusz Szuba, Thomas Kluyver, Alessandro Silenzi, Astrid Münnich, Michel Sliwa, Djelloul Boukhelef, Marc Messerschmidt, Krzysztof Wrona, Sandhya Venkatesan, Moritz Emons, C.M. Roome, Jacques-Philippe Colletier, Wajid Ehsan, Marco Kloos, Marco Cammarata, Jun Zhu, Lutz Foucar, Luis Maia, Max Lederer, Hans Fangohr, Marco Ramilli, Johan Bielecki, Ilme Schlichting, Sandor Brockhauser, Adrian P. Mancuso, Romain Letrun, R. Bruce Doak, Max Planck Institute for Medical Research [Heidelberg], Max-Planck-Gesellschaft, European XFEL GmbH (XFEL), European XFEL GmbH, Institut de Physique de Rennes (IPR), Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Centre National de la Recherche Scientifique (CNRS), Deutsches Elektronensynchrotron DESY, D-22607 Hamburg, Germany, Laboratoire Avancé de Spectroscopie pour les Intéractions la Réactivité et l'Environnement - UMR 8516 (LASIRE), Institut de Chimie du CNRS (INC)-Université de Lille-Centre National de la Recherche Scientifique (CNRS)-Centrale Lille Institut (CLIL), Institut de biologie structurale (IBS - UMR 5075 ), Université Grenoble Alpes [2016-2019] (UGA [2016-2019])-Institut de Recherche Interdisciplinaire de Grenoble (IRIG), Direction de Recherche Fondamentale (CEA) (DRF (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Direction de Recherche Fondamentale (CEA) (DRF (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Centre National de la Recherche Scientifique (CNRS), Rutgers University [Newark], Rutgers University System (Rutgers), Université de Rennes (UR)-Centre National de la Recherche Scientifique (CNRS), Institut de Chimie du CNRS (INC)-Université de Lille-Centre National de la Recherche Scientifique (CNRS), Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes [2016-2019] (UGA [2016-2019])-Institut de Recherche Interdisciplinaire de Grenoble (IRIG), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA), and ANR-17-CE11-0018,X-in-vivo,Cristallisation in vivo: une nouvelle stratégie pour étudier la structure et la dynamique des protéines dans les lasers à électrons libres et les synchrotrons.(2017)

Subjects
0301 basic medicine, Shock wave, Materials science, Science, General Physics and Astronomy, 02 engineering and technology, General Biochemistry, Genetics and Molecular Biology, Article, law.invention, 03 medical and health sciences, Optics, law, lcsh:Science, [PHYS]Physics [physics], Multidisciplinary, [SDV.BBM.BS]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Structural Biology [q-bio.BM], Femtosecond pulse, business.industry, Free-electron laser, X-ray, General Chemistry, 021001 nanoscience & nanotechnology, Laser, Pulse (physics), 030104 developmental biology, Femtosecond, lcsh:Q, ddc:500, 0210 nano-technology, business, Beam (structure)
Abstract

Nature Communications 9(1), 3487 (2018). doi:10.1038/s41467-018-05953-4, X-ray free-electron lasers (XFELs) enable novel experiments because of their high peak brilliance and femtosecond pulse duration. However, non-superconducting XFELs offer repetition rates of only 10–120 Hz, placing significant demands on beam time and sample consumption. We describe serial femtosecond crystallography experiments performed at the European XFEL, the first MHz repetition rate XFEL, delivering 1.128 MHz X-ray pulse trains at 10 Hz. Given the short spacing between pulses, damage caused by shock waves launched by one XFEL pulse on sample probed by subsequent pulses is a concern. To investigate this issue, we collected data from lysozyme microcrystals, exposed to a ~15 μm XFEL beam. Under these conditions, data quality is independent of whether the first or subsequent pulses of the train were used for data collection. We also analyzed a mixture of microcrystals of jack bean proteins, from which the structure of native, magnesium-containing concanavalin A was determined., Published by Springer Nature, London

Published
2018

9. A Time Projection Chamber with GEM-Based Readout

Author

Makoto Kobayashi, Vladyslav Krylov, Takeshi Matsuda, Leif J. Jönsson, R. Mehdiyev, J. Timmermans, Jochen Kaminski, M. S. Dixit, Yang Gao, Oliver Schäfer, Gilles De Lentdecker, Claus Kleinwort, Astrid Münnich, Katsumasa Ikematsu, Björn Lundberg, Fan Zhang, Junping Tian, Y. Kato, Amir Noori Shirazi, R. Yonamine, Sudeb Bhattacharya, Oleg Bezshyyko, Serguei Ganjour, Ulf Mjörnmark, Supratik Mukhopadhyay, Deb Sankar Bhattacharya, Vincent Hedberg, Keisuke Fujii, Anders Nils Erik Oskarsson, Philippe Gros, Ivor Fleck, Tohru Takahashi, Maksym Titov, Ralf Diener, Wenxin Wang, Tomohisa Ogawa, Yifan Yang, Ronald Settles, D. Tsionou, Ulrich Werthenbach, Takahiro Fusayasu, Martin Killenberg, Yulan Li, P. Colas, S. Caiazza, Alain Bellerive, Klaus Dehmelt, Ties Behnke, M. Riallot, Akira Sugiyama, Zhenwei Yang, Shin ichi Kawada, Nayana Majumdar, Annika Vauth, Takashi Watanabe, Klaus Kurt Desch, Klaus Zenker, D. Peterson, Peter Hayman, Bo Li, Purba Bhattacharya, Lennart Österman, Stefan Roth, Christoph Rosemann, M. Lupberger, Oxana Smirnova, Peter Schade, David Attié, F. Müller, Institut de Recherches sur les lois Fondamentales de l'Univers ( IRFU ), Commissariat à l'énergie atomique et aux énergies alternatives ( CEA ) -Université Paris-Saclay, Département de Physique des Particules (ex SPP) ( DPP ), Commissariat à l'énergie atomique et aux énergies alternatives ( CEA ) -Université Paris-Saclay-Commissariat à l'énergie atomique et aux énergies alternatives ( CEA ) -Université Paris-Saclay, LCTPC, Institut de Recherches sur les lois Fondamentales de l'Univers (IRFU), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay, Département de Physique des Particules (ex SPP) (DPP), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay, Laboratoire Leprince-Ringuet (LLR), and Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-École polytechnique (X)-Centre National de la Recherche Scientifique (CNRS)

Subjects
Nuclear and High Energy Physics, Drift velocity, Physics - Instrumentation and Detectors, International Linear Collider, Micropattern gaseous detectors (MPGD), Physics::Instrumentation and Detectors, FOS: Physical sciences, Tracking (particle physics), 01 natural sciences, law.invention, High Energy Physics - Experiment, Nuclear physics, High Energy Physics - Experiment (hep-ex), law, [ PHYS.HEXP ] Physics [physics]/High Energy Physics - Experiment [hep-ex], Gas electron multipliers (GEM), 0103 physical sciences, [PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex], International Large Detector (ILD), electron: irradiation, tracking detector, [PHYS.PHYS.PHYS-INS-DET]Physics [physics]/Physics [physics]/Instrumentation and Detectors [physics.ins-det], Detectors and Experimental Techniques, 010306 general physics, Instrumentation, spatial resolution, [ PHYS.PHYS.PHYS-INS-DET ] Physics [physics]/Physics [physics]/Instrumentation and Detectors [physics.ins-det], Physics, magnetic field: spatial distribution, International Linear Collider (ILC), Time projection chamber, 010308 nuclear & particles physics, ILD detector, Detector, drift velocity, DESY, Instrumentation and Detectors (physics.ins-det), Synchrotron, time projection chamber, efficiency, gas electron multiplier, Gas electron multiplier, Physics::Accelerator Physics, High Energy Physics::Experiment, Time projection chambers (TPC)
Abstract

For the International Large Detector concept at the planned International Linear Collider, the use of time projection chambers (TPC) with micro-pattern gas detector readout as the main tracking detector is investigated. In this paper, results from a prototype TPC, placed in a 1 T solenoidal field and read out with three independent GEM-based readout modules, are reported. The TPC was exposed to a 6 GeV electron beam at the DESY II synchrotron. The efficiency for reconstructing hits, the measurement of the drift velocity, the space point resolution and the control of field inhomogeneities are presented., 22 pages, 19 figures

Published
2017
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10. Status of the laboratory infrastructure for detector calibration and characterization at the European XFEL

Author

T. Dietze, Natascha Raab, M. Ekmedzič, Astrid Münnich, Monica Turcato, K.-E. Ballak, P.M. Lang, Rüdiger Schmitt, A. Kaukher, Steffen Hauf, Friederike Januschek, Markus Kuster, and Jolanta Sztuk-Dambietz

Subjects
Photon, Physics - Instrumentation and Detectors, Pixel, 010308 nuclear & particles physics, Computer science, business.industry, Physics::Instrumentation and Detectors, Detector, Detector calibration, Free-electron laser, FOS: Physical sciences, Instrumentation and Detectors (physics.ins-det), 01 natural sciences, Optics, Beamline, 0103 physical sciences, Calibration, 010306 general physics, business, Instrumentation, Mathematical Physics, Burst mode (computing)
Abstract

The European X-ray Free Electron Laser (XFEL.EU) will provide unprecedented peak brilliance and ultra-short and spatially coherent X-ray pulses in an energy range of 0.25 to 25 keV . The pulse timing structure is unique with a burst of 2700 pulses of 100 fs length at a temporal distance of 220 ns followed by a 99.4 ms gap. To make optimal use of this timing structure and energy range a great variety of detectors are being developed for use at XFEL.EU, including 2D X-ray imaging cameras that are able to detect images at a rate of 4.5 MHz, provide dynamic ranges up to 10$^5$ photons per pulse per pixel under different operating conditions and covering a large range of angular resolution. In order to characterize, commission and calibrate this variety of detectors and for testing of detector prototypes the XFEL.EU detector group is building up an X-ray test laboratory that allows testing of detectors with X-ray photons under conditions that are as similar to the future beam line conditions at the XFEL.EU as is possible with laboratory sources. A total of four test environments provide the infrastructure for detector tests and calibration: two portable setups that utilize low power X-ray sources and radioactive isotopes, a test environment where a commercial high power X-ray generator is in use, and a pulsed X-ray/electron source which will provide pulses as short as 25 ns in XFEL.EU burst mode combined with target anodes of different materials. The status of the test environments, three of which are already in use while one is in commissioning phase, will be presented as well as first results from performance tests and characterization of the sources., Comment: 8 pages, 7 figures including corrected captions with included copyright information also to be published in an erratum

Published
2017
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