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Megahertz serial crystallography

Authors :
Max O. Wiedorn
Dominik Oberthür
Richard Bean
Robin Schubert
Nadine Werner
Brian Abbey
Martin Aepfelbacher
Luigi Adriano
Aschkan Allahgholi
Nasser Al-Qudami
Jakob Andreasson
Steve Aplin
Salah Awel
Kartik Ayyer
Saša Bajt
Imrich Barák
Sadia Bari
Johan Bielecki
Sabine Botha
Djelloul Boukhelef
Wolfgang Brehm
Sandor Brockhauser
Igor Cheviakov
Matthew A. Coleman
Francisco Cruz-Mazo
Cyril Danilevski
Connie Darmanin
R. Bruce Doak
Martin Domaracky
Katerina Dörner
Yang Du
Hans Fangohr
Holger Fleckenstein
Matthias Frank
Petra Fromme
Alfonso M. Gañán-Calvo
Yaroslav Gevorkov
Klaus Giewekemeyer
Helen Mary Ginn
Heinz Graafsma
Rita Graceffa
Dominic Greiffenberg
Lars Gumprecht
Peter Göttlicher
Janos Hajdu
Steffen Hauf
Michael Heymann
Susannah Holmes
Daniel A. Horke
Mark S. Hunter
Siegfried Imlau
Alexander Kaukher
Yoonhee Kim
Alexander Klyuev
Juraj Knoška
Bostjan Kobe
Manuela Kuhn
Christopher Kupitz
Jochen Küpper
Janine Mia Lahey-Rudolph
Torsten Laurus
Karoline Le Cong
Romain Letrun
P. Lourdu Xavier
Luis Maia
Filipe R. N. C. Maia
Valerio Mariani
Marc Messerschmidt
Markus Metz
Davide Mezza
Thomas Michelat
Grant Mills
Diana C. F. Monteiro
Andrew Morgan
Kerstin Mühlig
Anna Munke
Astrid Münnich
Julia Nette
Keith A. Nugent
Theresa Nuguid
Allen M. Orville
Suraj Pandey
Gisel Pena
Pablo Villanueva-Perez
Jennifer Poehlsen
Gianpietro Previtali
Lars Redecke
Winnie Maria Riekehr
Holger Rohde
Adam Round
Tatiana Safenreiter
Iosifina Sarrou
Tokushi Sato
Marius Schmidt
Bernd Schmitt
Robert Schönherr
Joachim Schulz
Jonas A. Sellberg
M. Marvin Seibert
Carolin Seuring
Megan L. Shelby
Robert L. Shoeman
Marcin Sikorski
Alessandro Silenzi
Claudiu A. Stan
Xintian Shi
Stephan Stern
Jola Sztuk-Dambietz
Janusz Szuba
Aleksandra Tolstikova
Martin Trebbin
Ulrich Trunk
Patrik Vagovic
Thomas Ve
Britta Weinhausen
Thomas A. White
Krzysztof Wrona
Chen Xu
Oleksandr Yefanov
Nadia Zatsepin
Jiaguo Zhang
Markus Perbandt
Adrian P. Mancuso
Christian Betzel
Henry Chapman
Anton Barty
Source :
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
Publication Year :
2018
Publisher :
Nature Portfolio, 2018.

Abstract

The new European X-Ray Free-Electron Laser (EuXFEL) is the first XFEL that generates X-ray pulses with a megahertz inter-pulse spacing. Here the authors demonstrate that high-quality and damage-free protein structures can be obtained with the currently available 1.1 MHz repetition rate pulses using lysozyme as a test case and furthermore present a β-lactamase structure.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
9
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.748096d642ff4fc19840f7122cfc89d3
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-018-06156-7