1. Association between Testosterone/Estradiol Ratio and Risk of Cardiometabolic Diseases in Women at Menopause Transition Age
- Author
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Fabrice Boris Awadji, Bi Huang, Bryan Richard Sasmita, Samuel Chigbo Obiegbusi, Armin Czika, Yuzhou Xue, Suxin Luo, Alphonse Sowanou, and Gang Liu
- Subjects
cardiometabolic diseases ,testosterone/estradiol ratio ,menopause transition ,aging ,Gynecology and obstetrics ,RG1-991 - Abstract
Background: Imbalance of testosterone/estradiol ratio are frequently reported to be associated with the risk of cardiometabolic diseases; however, studies have yet to report the testosterone/estradiol ratio and its relationship to cardiometabolic diseases in women at menopause transition. This study aimed to explore the association between testosterone/estradiol ratio with cardiometabolic diseases in women during their menopausal transition age. Methods: 551 women aged from 45 to 55 years old were involved in this study. Their baseline information, disease comorbidity, blood biochemical tests, echocardiography and serum sex hormones were collected. Women were categorized by tertile distribution of testosterone/estradiol ratio. We used binary logistic regression model (for odds ratio) and poissoon loglinear model (for prevalence ratio) to evaluate the association between testosterone/estradiol ratio with cardiometabolic diseases. Results: The mean age of the study population was 48.6 ± 3.5 years old. Taking testosterone/estradiol ratio
- Published
- 2022
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