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Your search keyword '"Area Under Receiver Operating Characteristics Curve (AUROC)"' showing total 2 results
Start Over Descriptor "Area Under Receiver Operating Characteristics Curve (AUROC)"
2 results on '"Area Under Receiver Operating Characteristics Curve (AUROC)"'

1. Detection and characterization of traumatic bile leaks using Gd-EOB-DTPA enhanced magnetic resonance cholangiography

Author

Yon-Cheong Wong, Li-Jen Wang, Cheng-Hsien Wu, Huan-Wu Chen, Chen-Ju Fu, Kuo-Ching Yuan, Being-Chuan Lin, Yu-Pao Hsu, and Shih-Ching Kang

Subjects
Bile Leakage, Contrast-enhanced Magnetic Resonance Cholangiography (CEMRC), Area Under Receiver Operating Characteristics Curve (AUROC), Detect Bile Leaks, Gadoxetic Acid Disodium, Medicine, Science
Abstract

Abstract Expanding bile leaks after blunt liver trauma require more aggressive treatment than contained bile leaks. In this retrospective study approved by institution review board, we analyzed if non-invasive contrast-enhanced magnetic resonance cholangiography (CEMRC) using hepatocyte-specific contrast agent (gadoxetic acid disodium) could detect and characterize traumatic bile leaks. Between March 2012 and December 2014, written informed consents from 22 included patients (17 men, 5 women) with a median age of 24.5 years (IQR 21.8, 36.0 years) were obtained. Biliary tree visualization and bile leak detection on CEMRC acquired at 10, 20, 30, 90 minutes time points were independently graded by three radiologists on a 5-point Likert scale. Intraclass Correlation (ICC) was computed as estimates of interrater reliability. Accuracy was measured by area under receiver operating characteristic curves (AUROC). Biliary tree visualization was the best on CEMRC at 90 minutes (score 4.30) with excellent inter-rater reliability (ICC = 0.930). Of 22 CEMRC, 15 had bile leak (8 expanding, 7 contained). The largest AUROC of bile leak detection by three radiologists were 0.824, 0.914, 0.929 respectively on CEMRC at 90 minutes with ICC of 0.816. In conclusion, bile leaks of blunt liver trauma can be accurately detected and characterized on CEMRC.

Published
2018
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2. Detection and characterization of traumatic bile leaks using Gd-EOB-DTPA enhanced magnetic resonance cholangiography

Author

Being Chuan Lin, Yu Pao Hsu, Shih Ching Kang, Kuo Ching Yuan, Chen Ju Fu, Yon-Cheong Wong, Cheng-Hsien Wu, Huan Wu Chen, and Li-Jen Wang

Subjects
Gadoxetic Acid Disodium, Adult, Gadolinium DTPA, Male, Intraclass correlation, Science, Gd-EOB-DTPA, Contrast Media, Wounds, Nonpenetrating, Article, 030218 nuclear medicine & medical imaging, 03 medical and health sciences, 0302 clinical medicine, Cholangiography, Medicine, Humans, Area Under Receiver Operating Characteristics Curve (AUROC), Bile leak, Retrospective Studies, Observer Variation, Multidisciplinary, medicine.diagnostic_test, Receiver operating characteristic, business.industry, Contrast-enhanced Magnetic Resonance Cholangiography (CEMRC), Reproducibility of Results, 030208 emergency & critical care medicine, Magnetic resonance imaging, Bile Leakage, Magnetic Resonance Imaging, Gadoxetic acid disodium, Tree visualization, Detect Bile Leaks, Liver, ROC Curve, Area Under Curve, Female, Bile Ducts, business, Nuclear medicine
Abstract

Expanding bile leaks after blunt liver trauma require more aggressive treatment than contained bile leaks. In this retrospective study approved by institution review board, we analyzed if non-invasive contrast-enhanced magnetic resonance cholangiography (CEMRC) using hepatocyte-specific contrast agent (gadoxetic acid disodium) could detect and characterize traumatic bile leaks. Between March 2012 and December 2014, written informed consents from 22 included patients (17 men, 5 women) with a median age of 24.5 years (IQR 21.8, 36.0 years) were obtained. Biliary tree visualization and bile leak detection on CEMRC acquired at 10, 20, 30, 90 minutes time points were independently graded by three radiologists on a 5-point Likert scale. Intraclass Correlation (ICC) was computed as estimates of interrater reliability. Accuracy was measured by area under receiver operating characteristic curves (AUROC). Biliary tree visualization was the best on CEMRC at 90 minutes (score 4.30) with excellent inter-rater reliability (ICC = 0.930). Of 22 CEMRC, 15 had bile leak (8 expanding, 7 contained). The largest AUROC of bile leak detection by three radiologists were 0.824, 0.914, 0.929 respectively on CEMRC at 90 minutes with ICC of 0.816. In conclusion, bile leaks of blunt liver trauma can be accurately detected and characterized on CEMRC.

Published
2018

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