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Copyright of Osmangazi Journal of Medicine / Osmangazi Tip Dergisi is the property of Eskisehir Osmangazi University and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Among the reactive oxygen species, Superoxide radicals can produce dangerous species that cause lipid peroxidation. Therefore, the determination and scavenging of superoxide radicals is critical. Our study is based on the interaction of the superoxide radical produced from the β-Nicotinamide adenine dinucleotide reduced disodium salt hydrate and phenazine methosulfate (NADH-PMS) system with N, N-dimethyl-p-phenylenediamine dihydrochloride (DMPD) to form the pink colored DMPD-quinone (DMPDQ) radical. In the presence of scavengers with superoxide radical scavenging activity (antioxidants, herbal teas) the color intensity decreases due to reduced DMPDQ radical production. The absorbance of the colored reference solution and the sample solution containing the radical scavenger was measured at 552 nm. The difference in absorbance (ΔA) between the reference solution and the sample solution was found. ΔA is proportional to the scavenger concentration. In the study, the superoxide radical scavenging effect of trolox (TR) and different AOXs was investigated. The superoxide radical scavenging effect of three different herbal tea infusion solutions was measured with this method. From the graph drawn between herbal tea concentrations and percentage inhibition values, 50% inhibition (EC50) values of herbal teas were found. EC50 method values were compared with the EC50 values of the nitroblue tetrazolium (NBT) and the 2,2'-azino-bis(3-etilbenzotiyazolin-6-sülfonik asit (ABTS) method. In addition, ABTS, cupric reducing antioxidant capacity (CUPRAC), and this study total antioxidant capacity (TAC) values of herbal tea infusions were calculated and compared.

Copyright of Afyon Kocatepe University Journal of Science & Engineering / Afyon Kocatepe Üniversitesi Fen Ve Mühendislik Bilimleri Dergisi is the property of Afyon Kocatepe University, Faculty of Science & Literature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

This study focused on extracting antioxidants from hazelnut skin, an industrial food waste, using two different methods: conventional extraction (CE) and ultrasound-assisted extraction (UAE). The Response Surface Methodology (RSM) has been utilized using the total phenolic content (TPC) and antioxidant capacity (AC) results as responses in optimizing both method conditions. The independent variables and their levels for the optimal experimental design were adjusted as follows: temperature (50-90°C), time (2-62 min), and loading capacity (5-15%) for CE; and temperature (25-50°C), time (1-30 min), loading capacity (5-15%), and ultrasonic amplitude (20-50%) for UAE. The optimum conditions were determined to be 90°C for 35 min with a 5% loading capacity for CE, and 50°C for 27 min with a 5% loading capacity and 50% amplitude for UAE. The TPC of the extracts were found to be 142.62 mg GAE/g and 129.69 mg GAE/g, while the AC values were 127.02 µmol TE/g and 116.00 µmol TE/g for CE and UAE methods, respectively. In conclusion, it has been demonstrated that hazelnut skin extracts obtained by optimizing CE and UAE methods can serve as natural antioxidant alternatives in food products and may hold significant potential for further applications. [ABSTRACT FROM AUTHOR]

Copyright of Health Academy Kastamonu / Sağlık Akademisi Kastamonu is the property of Health Academy Kastamonu / Saglik Akademisi Kastamonu and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

In this study, some physicochemical, antioxidant properties and in-vitro bioaccessibility of bread enriched with yarrow and dandelion powder at three different ratios (1%, 2%, 3%) were determined. The antioxidant capacity was determined as 20.50 μmol TE/g in the bread with 3% yarrow addition and 19.75 μmol TE/g in the bread with 3% dandelion addition according to the CUPRAC method. The total phenolic content was 45.76 mg GAE/100g in the control group and 62.23 and 61.40 mg GAE/100g in the bread with 3% yarrow and dandelion, respectively. It was detected that the bioaccessibility values of the phenolic compounds of the bread subjected to the enzymatic extraction process ranged between 69-73%. The study revealed that the bread enriched with medicinal plants, known for their positive effects, exhibited higher levels of ash, total phenolic content, and antioxidant capacity in comparison to the control group. [ABSTRACT FROM AUTHOR]

Copyright of Gazi Üniversitesi Fen Bilimleri Dergisi Part C: Tasarım ve Teknoloji is the property of Gazi University and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Çukurova Journal of Agriculture & Food Sciences is the property of Cukurova University and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Agriculture & Nature / Kahramanmaraş Sütçü İmam Üniversitesi Tarım & Doğa Dergisi is the property of Kahramanmaras Sutcu Imam Universitesi and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Kombucha is a sour-sweet beverage that is characterized by acetic acid and alcohol fermentation that occurs with the symbiotic relationship of acetic acid bacteria and yeasts in the kombucha culture. This study aimed to increase the bioactive potential of Kombucha, which has many health benefits. Kombucha was prepared by fermentation following the addition of medlar (Mespilus germanica L.) fruit to green tea at different rates (5%, 10%, and 20%). These teas were evaluated regarding antioxidant capacity, total phenolic content, and bioaccessibility. It was observed that the bioactive potential increased with the increase in the ratio of medlar added to the Kombucha samples. With the addition of medlar at the level of 20%, the antioxidant capacity of bioaccessible phenolic fractions for the DPPH method increased from 26.21±0.25 μmol TE/mL to 38.54±0.08 μmol TE/mL, and the total phenolic content increased from 42.83±1.02 mg GAE/100 mL to 42.83±1.02 mg GAE/100 mL. Kombucha prepared with the addition of medlar fruit has revealed a beverage with high bioactive content and also demonstrated the potential to increase the industrial use of the wild medlar fruit. [ABSTRACT FROM AUTHOR]

The quality of agricultural crops is influenced by growing conditions and post-harvest processes, including drying. Moreover, the total phenolic and total antioxidant content in the product's structure and composition can be either positively or negatively affected by the heat treatments applied during drying. Additionally, the specific growing conditions and methods of water removal can lead to the development of distinct drying characteristics. There was no study comparing the drying kinetics and quality parameters of organic (OBC) and conventional (CBC) black carrot in the literature studies. In this study were aimed that mathematically modelling the drying kinetics for OBC and CBC with IMW (150, 300, 450 W) and HA (60, 70, 80°C), determining their differences and evaluating the effects of methods on quality properties. The results showed that L* and ΔE values of the final products increased significantly by increasing the power and temperature levels applied during drying and the powder samples were lighter in color compared to the fresh samples. The total phenolic and total antioxidant capacity values were higher in fresh OBC samples compared to the conventional variety. This result shows that OBC is superior to the CBC in terms of higher total phenolic and total antioxidant content. The activation energy (Ea) values of OBC and CBC dried by IMW and HA were calculated as 8.41x10-3; 8.40x10-3 Wg-1 and 25.50; 19.72 kJ mol-1, respectively. The Logistic and Verma were the best fit models for describing IMW and HA drying kinetics, respectively. The samples obtained with IMW drying, which resulted in a shorter drying time, were more effect in terms of preserving and increasing the total phenolic and antioxidant content compared to dried samples with HA. The results showed that that the temperature/power levels applied to the products during the drying process, thus the drying times and the methods of removing moisture from the product are effective in the preservation of the total phenolic components. [ABSTRACT FROM AUTHOR]

Copyright of Erzincan University Journal of Science & Technology is the property of Erzincan Binali Yildirim Universitesi and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

In order to optimize the experimental conditions for the ultrasonic assisted extraction of phenolic compounds from chicory leaves, a five level five factor central composite design response surface methodology was used. Total phenolic content and antioxidant capacity were selected as the response and 48 experiments were performed using five independent variables; time (min), HCl concentration (mol/L), temperature (ºC), liquid/solid ratio (mL/g) and methanol concentration (%). As a result of optimization, optimum conditions, for maximum total phenolic content were determined as temperature 73 ºC, time 69 min, methanol 84%, HCl concentration 0.57 mol/L and liquid/solid ratio 33.97 mL/g. The optimum conditions, for maximum antioxidant capacity were temperature 73 ºC, time 69 min, methanol 85%, HCl concentration 0.47 mol/L and liquid/solid ratio 33.99 mL/g. The total phenolic content of white chicory extract obtained as a result of extraction under optimum conditions was determined as 33.5±0.5 mg GAE/g dried plant and antioxidant capacity as 7.2±0.1 mg TE/g dried plant. [ABSTRACT FROM AUTHOR]

Copyright of Journal of Agriculture & Nature / Kahramanmaraş Sütçü İmam Üniversitesi Tarım & Doğa Dergisi is the property of Kahramanmaras Sutcu Imam Universitesi and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

In this study, bioactive compounds (phenolics) from carob pod were extracted by using microwave assisted extraction method. Spray drying technique was performed for the conversion of the resulting extract into powder form. Microwave assisted extraction and spray drying steps were optimized using response surface methodology. In the extraction stage, the effect of solvent temperature and extraction time on the total phenolic content was evaluated. Optimum extraction conditions (total phenolic content: 84.48 mg GAE/g) were determined as 55 °C and 26 min. For the final powder production, the maximum process yield (48.00%) was obtained at the point where the spray dryer inlet temperature was 184 °C and the flow rate was 8 mL/min. The presence of phenolic structures in final product was verified by FTIR spectroscopy. Total phenolic content (15.37 mg GAE/g) and antioxidative behavior (DPPH: 0.63 mmol TE/g, ABTS: 0.30 mmol TE/g, FRAP: 0.06 mmol TE/g, CUPRAC: 0.05 mmol TE)/g) of carob powders were evaluated. [ABSTRACT FROM AUTHOR]

In this study, sumac plant (Rhus coriaria L.) naturally grown in Tunceli (Türkiye) was collected from 5 different provinces and investigated for their phytochemical properties. In sumac samples, pH, color, ash amount, total phenolic content (TPC), 2,2-diphenyl-1-picrylhydrazyl (DPPH) free radical scavenging capacity, metal chelating capacity, copper (II) ion reducing antioxidant capacity (CUPRAC), reducing power, mineral matter content, organic acids as tartaric acid, malic acid and citric acid, phenolic compounds as gallic acid, vanillic acid, caffeic acid, routine, resveratrol, (-)- epicatechin, and (+)- catechin hydrate contents were determined. The highest TPC was found in the acidified methanol extract (AME) and the DPPH free radical scavenging capacity was found in the acidified acetonitrile extract (AAE). It was determined that all extracts of sumac sample 5 (S5) collected from Pertek district, metal chelating capacity was higher than the other samples but lower than the metal chelating capacity of ethylene diamine tetra acetic acid (EDTA). CUPRAC was detected at the highest concentration of 118.0±3.0 mg caffeic acid equivalent kg-1 (mg CAE kg-1) in the AME, at the lowest 10.2±0.6 mg CAE kg-1 in the AAE for S5 sample. It was found that the reducing powers of all samples were found to be lower than the reducing power of synthetic antioxidants (butylhydroxytoluene (BHT), a tocopherol, and vitamin C), and the samples were rich in mineral substances, the predominant organic acid was malic acid, and phenolic compound was gallic acid. [ABSTRACT FROM AUTHOR]

Copyright of Harran Journal of Agricultural & Food Science is the property of Harran University, Faculty of Agriculture and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Agriculture & Nature / Kahramanmaraş Sütçü İmam Üniversitesi Tarım & Doğa Dergisi is the property of Kahramanmaras Sutcu Imam Universitesi and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Agriculture & Nature / Kahramanmaraş Sütçü İmam Üniversitesi Tarım & Doğa Dergisi is the property of Kahramanmaras Sutcu Imam Universitesi and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

The aim of this study is to investigate the effect of essential oil mixture supplemented in drinking water on antioxidant capacity and intestinal health in geese. One hundred eight chicks (which were 3 days old) were randomly allocated to 3 groups and each group was allocated to 6 subgroups. Research groups have been as follows: C (Control; without supplementation); E1 (0.4 ml/L essential oil mixture supplementation) and E2 (0.8 ml/L essential oil mixture supplementation). The duration of the experiment was 13 weeks. In the first 4 weeks of the trial, the animals were fed for the chick period. In the last 9 weeks of the trial, geese were fed in the pasture under the conditions of Kars province. In the 4th week and at the end of the experiment, GSH exhibited a linear response (P=0.008 and P=0.004, respectively). However, MDA, GSH, SOD, GPx, CAT, nitric oxide, ceruloplasmin, albumin, total protein and globulin were not affected. At the end of the experiment, acetic acid, butyric acid, isocaproic acid and total short-chain fatty acid concentrations were linearly affected with the gradued level of essential oil mixture. There were no significant differences in propionic acid, isobutyric acid, valeric acid, isovaleric acid, caproic acid and BCFA concentrations. In conclusion, water containing essential oil mixture in geese can be used to improve antioxidant capacity and intestinal health. [ABSTRACT FROM AUTHOR]

Copyright of SDU Journal of Engineering Sciences & Design / Mühendislik Bilimleri ve Tasarım Dergisi is the property of Journal of Engineering Sciences & Design and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Coffee is one of the most frequently consumed beverage that has an important place in our daily life. Owing to bioactive components in its content, it has antioxidant, antihypertensive, anti-inflammatory, immunoprotective, anti-carcinogenic effects on health. Within the scope of the study, it is aimed to compare the bioactive potential of commercially available Espresso, Americano, Macchiato, Latte, Cappuccino and Mocha coffee drinks by analyzing the antioxidant capacity (ABTS and DPPH Methods) and the total phenolic compound (Folin-Ciocalteu Method). The highest values were determined in the Espresso sample, which has the most intense coffee content; extractable, hydrolyzable, bioaccessible phenolic fractions were determined respectively as 28.15, 35.04, 30.28 μmol Troloks mL-1 according to TEACABTS and 14.69, 17.98, 9.84 μmol Troloks mL-1 according to TEACDPPH. By the increase of the milk amount in coffee samples, decrease was observed in the antioxidant capacity and total phenolic content results. Addition of steamed milk by steaming treatment showed relatively higher values compared to adding milk as hot. The bioaccessibility % of the samples varied between 41-48 % according to total phenolic content. [ABSTRACT FROM AUTHOR]

Son yıllarda keçi sütü ile üretilen ürünlere talep artmaktadır. Buna karşın, keçi sütünün inek sütüne kıyasla bileşen ve lezzet farklılıkları keçi sütü ile üretilen ürünlerin özelliklerinde önemli farklılıklara sebep olabilmekte ve ürünün kabul edilebilirliğini etkilemektedir. Bu çalışmada, keçi sütü ile üretilen kefirin antioksidan kapasitesinin, reolojik ve duyusal özelliklerinin inek sütüyle üretilen kefirin, söz konusu özellikleriyle kıyaslanması amaçlanmıştır. Bu çerçevede, inek sütü, keçi sütü ve 1:1 oranında inek ve keçi sütlerinin karışımıyla kefir üretilmiş, fiziko-kimyasal, reolojik ve duyusal analizleri gerçekleştirilmiştir. Bütün kefir örneklerinin reolojik özelliklerinin psödoplastik davranış gösterdiği ve üssel modele uygun olduğu belirlenmiştir. Keçi sütü ile üretilen kefir örneğinin ise görünür viskozite değerleri inek sütü ile üretilen kefirlere kıyasla düşük bulunmuştur. Keçi sütü kefirinin toplam antioksidan kapasitesinin de inek sütü kefirine kıyasla daha yüksek, renkte a ve b değerlerinin ise daha düşük olduğu tespit edilmiştir. Buna karşın, keçi sütü kefirinde, panelistler tarafından daha düşük kıvam ve kefir lezzeti algılanarak tüm izlenim açısından da daha düşük puanlar almıştır. Keçi sütüne %50 oranında inek sütü ilavesi ise, keçi sütünün yarattığı bu durumu etkilemiş ve duyusal özellikleri tamamıyla inek sütü kefirinin duyusal özelliklerine benzerlik göstermiştir. Dolayısıyla, inek sütü karışımı olumlu sonuçlar vermekle birlikte, sadece keçi sütünden kefir üretiminde daha iyi kıvam ve lezzet eldesi için daha ileri çalışmaların yapılması gerektiği sonucuna varılmıştır.

This is the first study conducted on a variety of rice (Oryza sativa L.) traditionally grown in the Konuralp region of the Duzce province, in the West Black Sea region of Türkiye. It investigated the physico-chemical composition, phyto-chemical properties, cooking characteristics and bioactive compounds (total phenolic content, antioxidant activity determined with the methods of ABTS•+, CUPRAC, DPPH• and FRAP) of Konuralp Rice (KR) as well as in-vitro bioaccessibility. The proximate chemical composition of the rice was found to be as follows: the moisture content was 13.89%, the protein content was 6.48%, the total dietary fiber was 0.82%, the energy value was 323.44 kcal and the amount of starch was 59.64%. On the other hand, the phytic acid content of the sample was found to be 258.69 mg/100g. The total phenolic content of KR was found to be 2100 mg GAE/100g. The highest antioxidant capacity was found in the method of DPPH• for extractable (12.73 µmol trolox/g) and hydrolyzable phenolics (62.50 µmol trolox/g). The antioxidative bioaccessibility were found to be 80.19% (ABTS•+), 27.96% (CUPRAC), 20.63% (DPPH•) and 0.92% (FRAP). Due to the its physico-chemical and phyto-chemical properties as well as its high bioactive component content, more attention should be paid to the traditionally produced KR. [ABSTRACT FROM AUTHOR]

Hazelnut providing the macro-and micronutrients is a constituent of the healthy diet. Hazelnut, one of the most consumed treenut, is produced in the different countries. The geographical origin influences the chemical composition and the biological activity in the several plant foods. The purpose of this study is to evaluate the chemical composition, the antioxidative capacity and total phenolic content of the hazelnut kernels obtained from the different countries, including Azerbaijan, Chile, Italy, and Turkey. The hazelnut kernels were examined for crude oil, ash, moisture, and protein contents. The refractive index, iodine value, and fatty acid composition of the hazelnut oils were identified. In addition, the hazelnut oil, the kernels, and the defatted kernels were tested for their antioxidative activities and total phenolic contents. Protein contents of the hazelnuts from different countries were similar. The largest oil yield was determined in the hazelnut kernels from Chile and Turkey (62.35 ± 0.51 % and 62.29 ± 0.46 %, respectively). While the oil from Turkish hazelnut kernels showed the highest oleic acid content (84.09 ± 0.17 %), Azerbaijan hazelnut oil had the lowest oleic acid content (78.10 ± 0.48). The highest phenolic content was detected in the hazelnut kernels from Azerbaijan. Although the lowest phenolic content was observed in the hazelnut kernels from Turkey, the most potent antioxidative capacity was determined in the Turkish hazelnut kernels, their oil, and their defatted form. It can be concluded that the Turkish hazelnut kernels could contain high amounts of the fat-soluble antioxidants in addition to the water-soluble phenolic antioxidants. The results suggested that the hazelnuts exhibited different chemical composition, antioxidant capacity, and phenolic content depending on their origin. [ABSTRACT FROM AUTHOR]

The aim of this study was to determine the yield and various quality characteristics of two different strawberry cultivars (Fragaria x ananassa var. Festival and Camarosa), grown in the ecological conditions of Sultanhisar, Aydın, Turkey. The study was conducted over two years, in ten randomly selected open grown plantations for each of the two cultivars. When the fruits reached harvest maturity, they were harvested and their yield values, mean fruit weight, fruit diameter, fruit length, fruit firmness, colour, pH, titrable acidity, water-soluble dry matter, vitamin C content, total antioxidant capacity and total phenolics were determined. According to the results obtained, yield values fell in the second year of the study, but mean fruit weight, diameter and length increased. Similarly, the fruit firmness of both varieties was considerably greater in the second year, and these differences between the years were found to be statistically significant. While the highest antioxidant capacity and phenolic content were obtained from the Festival cultivar, the highest vitamin C content was found in the Camarosa cultivar. The changes of total antioxidant capacity and the amount of total phenolics according to years of both varieties were found to be statistically significant.

In this study, antioxidant capacity and antimicrobial effect values of honeydew honey obtained from Ida Mountains region being rich in biodiversity were determined. According to the results of electrical conductivity and pollen analyses; 25 honeydew honey samples collected from the Ida Mountains region of the towns of Çanakkale province; Ayvacık, Bayramiç, Çan and Yenice. DPPH% antioxidant capacity values of honeydew honeys were found out to vary between 41.50% - 78.98%. It was also determined that some honeydew honey samples have high antioxidant capacity values such as 74.83%- 78.27%, 78.69% and 78.98%. It was determined that honeydew honey samples have antimicrobial effect on Staphylococcus aureus ATCC 25923 and Escherichia coli ATCC 1301 microorganisms. It was found out that the samples have no antimicrobial effect on Bacillus cereus ATCC 6633, Candida albicans ATCC 10231 and Saccharomyces cerevisiae ATCC 9763 microorganisms.

Objective: Methotrexate (MTX) is an important chemotherapeutic and an important anticarcinogen used in cancer patients, but it causes side effects in other tissues. Among these side effects is lung toxicity. Vitamin B12 is a powerful antioxidant and reduces reactive oxygen species. This study was designed to determine whether vitamin B12 could protect against methotrexate-induced damage in rat lungs. Methods: A total of 32 male Wistar albino rats were divided into four groups: The control group (n=8) received intraperitoneal (i.p.) saline throughout the experiment. Vitamin B12 group (B12) (n=8) 3 µg/ kg/i.p. Vitamin B12 was administered for 14 days. The methotrexate (MTX) group received a single dose MTX injection at 20 mg/kg/i.p. on the 8th day of the experiment. On the 8th day of the experiment, a single dose of MTX 20 mg/kg/i.p. was given to the MTX+B12 group. + 3 µg/kg/i.p. Vitamin B12 was administered daily throughout the experiment. Histopathological, immunohistochemical, and biochemical methods were applied to the obtained lung tissues. Lung tissues were stained with Masson's Trichrome (MT). In addition, α-Sma, Laminin, PCNA, and TNF-α antibodies were stained by immunohistochemistry. Superoxide dismutase (SOD), catalase (CAT), and malondialdehyde (MDA) levels were evaluated in lung tissue homogenates. Results: MTX caused an increase in MDA and IL-6 levels and expression of α-Sma, Laminin, and TNF-α, and the number of apoptotic cells in lung tissue. It also caused a decrease in PCNA expression and SOD and CAT levels in the MTX group. Vitamin B12 inhibited the increase in MDA and IL-6 levels and the expression of α-Sma, Laminin, and TNF-α. Vitamin B12 was found to increase antioxidant capacity. Conclusion: Vitamin B12 has been shown to be effective on factors such as oxidative stress, inflammation, fibrosis, and apoptosis in MTX-induced lung toxicity and reduce damage. We observed that MTX stimulated lung injury decreased with vitamin B12 treatment It suggests that vitamin B12 should not be ignored in reducing side effects in cancer drug use. [ABSTRACT FROM AUTHOR]

Objectives: Ephedra nebrodensis (Ephedraceae) presents a wide range of biological activities. It is used to treat respiratory problems and hepatic pathologies in traditional medicine. The aim of this study is to evaluate the antioxidant, in vitro and in vivo anti-inflammatory and analgesic properties of two hydro-alcoholic extracts of E. nebrodensis in mice. Materials and Methods: The antioxidant capacity of hydro-methanolic (HM) and hydro-ethanolic (HE) extracts of E. nebrodensis was evaluated via assays of their superoxide radical scavenging capacity and ferrous ion chelating activity. The in vitro anti-inflammatory activity of the extracts (5, 10, and 20 mg/kg) was also determined using the bovine serum albumin denaturation test. Croton oil-induced ear edema was then employed to evaluate the in vivo anti-inflammatory effect of the extracts (200 and 400 mg/kg). Finally, the analgesic activity of the extracts (200 and 400 mg/ kg) was determined by the acetic acid-induced torsion test. Results: The hydro-alcoholic extracts of E. nebrodensis present significant antioxidant activity. The HE and HM could inhibit protein denaturation by 82.99%±20.21% and 56.25%±2.12%, respectively. The extracts (HM and HE) also show strong anti-inflammatory effects in vivo and could reduce ear edema by 70.37%±2.00% and 72.22%±1.94%, respectively. The HM extract (72.51%±2.43%) demonstrates greater pain inhibitory effects than HE (70.76%±2.58%). Conclusion: The hydro-alcoholic extracts of E. nebrodensis produce antioxidant, anti-inflammatory, and analgesic effects. These results confirm the traditional use of the herb in the treatment of various diseases. [ABSTRACT FROM AUTHOR]

Cornelian cherry (Cornus mas L.) has regained an increasing interest because of its nutraceutical and pharmaceutical potential. This study was designed to investigate the phenolic compounds (total phenolic, flavonoid, hydrolysable tannin, proanthocyanidin and anthocyanidin) and antioxidant capacity of Cornelian cherries. Some morphological (length, width, weight, flesh:seed ratio and colour) and physicochemical properties (dry matter, pH, soluble solid content, total acidity, sugar profile and ascorbic acid) of Cornelian cherries were also examined. Cornelian cherry samples were selected from twelve locations in the Çorum province of Turkey, where they are grown natively. Bioactive compounds were extracted by an ultrasound assisted method (37 kHz frequency and 100% amplitude) for 20 min at 20±2°C. Aqueous methanol (70%) was used as extraction solvent with the solid:solvent ratio of 1:20. Glucose (3.02±0.9%) and fructose (1.57±0.4%) were found as the main sugars in cherry fruits. The CIE* colour values ranged from 25.18 to 33.00 for L*, 9.74 to 30.26 for a*, 2.46 to 14.41 for b* values. Total phenolic content, flavonoids, total anthocyanin, proanthocyanins, hydrolysable tannins, ascorbic acid and antioxidant activity varied between 230.4-559.8 mg GAE/100 g, 28.3-94.7 mg CE/100 g, 69.2-200.5 mg/100 g, 124.1-316.3 mg CE/100 g, 151.6-568.9 mg TAE/100 g, 29.0-103.3 mg/100 g, 24.4-92.5 μM TE/g, respectively. Antioxidant activity was positively correlated with bioactive content of Cornelian cherry fruits (p<0.001). The native Cornelian cherry population with the high antioxidant potential may be useful for future breeding programs, organic production or as food additive. [ABSTRACT FROM AUTHOR]

In this study, six berry fruits; goji berry/wolfberry (Lycium barbarum), black mulberry (Morus nigra), white mulberry (Morus alba), blackberry (Rubus fructicous L.), purple mulberry (Morus rubra) and Bursa Black mulberry (unknown) were analyzed by HPLC-FD to determine whether they present melatonin. The melatonin was detected different amounts in all samples. Besides, the total phenolic content and antioxidant capacity were studied in all fruit samples. DPPH and ABTS tests were applied to determine the antioxidant capacity. It was observed that the amount of melatonin in the fruit samples varied between 123.44 and 1600.48 ng/gFW. It was found that the concentration of melatonin in goji berry (BF1) was higher than other berry fruits. The highest total phenolic content and antioxidant capacity to were obtained from purple mulberry (BF6) as 276.83 mg GAE/100 gFW, 452.38 mg TE/100 gFW (DPPH) and 555.73 mg TE/100 gFW (ABTS), respectively. Results reveals a significant positive correlation between the total phenolic content with antioxidant capacity. [ABSTRACT FROM AUTHOR]

Copyright of Yuzuncu Yil Universitesi Journal of Agricultural Sciences (YYU J Agr Sci) is the property of Yuzuncu Yil University and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Agriculture & Nature / Kahramanmaraş Sütçü İmam Üniversitesi Tarım & Doğa Dergisi is the property of Kahramanmaras Sutcu Imam Universitesi and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Antioxidants, usually contain phenolic groups, molecules may prevent the formation of free radicals or by blocking the radicals to prevent damage to the cell. Antioxidant molecules can be produced by the body or taken into the body through foods. Today, there are many different methods used to measure antioxidant capacity. In these methods, measurements are usually carried out by adding the tested substances into a solution containing free radicals. These methods can give different results depending on the characteristics of the reactant used. In this study, the reproducibility and consistency of five different antioxidant capacity methods (DPPH, ABTS, galvinoxil, phosphomolybdenum and FRAP) in commercially available and homemade turnip samples were tested. At the end of the study, antioxidant activities of the tested samples were evaluated. According to the evaluation of the antioxidant activities (from higher to lower) of these samples, the results of, DPPH, galvinoxyl, phosphomolybdenum and FRAP methods were very similar. However, ABTS method results showed difference compared to other method results. As a result of study, reproducibility and consistency of results of DPPH, galvinoxyl, phosphomolybdenum and FRAP methods were determined.

In this study, phenolic compounds (PCs) were extracted from fenugreek seeds (Trigonella foenumgraecum L.) by mechanical agitation using pure water at different temperatures. The effects of the extraction temperature, extraction time, and agitation rate on the total PCs (TPCs), total flavonoids (TFLs), and antioxidant capacities (ACs) of the extracts were investigated. Optimum conditions for which TPCs, TFLs, and ACs reached their highest value were determined using the desirability function of the central composite design. Optimization results at 45°C extraction temperature, 65 min extraction time, and 20000 rpm agitation rate showed that TPCs were 137.37 ± 1.87 mg gallic acid/g dry sample, TFLs were 86.96 ± 1.44 mg quercetin/g dry sample, and ACs were 18.11±0.55 mM Trolox/g dry sample. The fenugreek seed extracts having high amounts of phenolic compounds and high antioxidant capacity are believed to have the potential for use in different food formulations. [ABSTRACT FROM AUTHOR]

Copyright of Harran Journal of Agricultural & Food Science is the property of Harran University, Faculty of Agriculture and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Persimmon which is widely known as "Trabzon Hurması" and "Cennet Meyvesi" is a very popular fruit with bright orange color. In the presented study, extractable, non-extractable, total phenolic content (TPC), antioxidant capacity (AC) and bioaccessibility of Trabzon persimmons (astringent, non-astringent and wild persimmon) were determined. The results of this study indicated that all types of persimmons have great importance both on TPC, AC and bioaccessibility. Compared to astringent and non-astringent types, the wild persimmon type had the highest TPC. Another attractive result from this study, although the wild persimmons do not prefer for consumption, the results demonstrated that the bioaccessible phenolics of this type of persimmons were found to be 6.7 fold higher than the non-astringent types and 4.7 fold higher than the astringent types. Especially the wild type of persimmon is a good source of natural antioxidant and further studies should be carried out for wild type persimmon. [ABSTRACT FROM AUTHOR]

Copyright of Mersin Üniversitesi sağlık Bilimleri Dergisi is the property of Mersin University and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

In this study, the effect of microwave, hot air and microwave-hot air combination on the physical and chemical properties of Iğdır apricot, which was subjected to ultrasound pre-treatment, was investigated. For this purpose, 10 minutes of ultrasound pre-treatment was applied to apricot fruit samples exposed to various drying processes including microwave (100 W), hot air (50 and 75 °C) and microwave-hot air combination (100 W-50 °C, 100 W-75 °C). In addition to bioactive compounds including total phenolic substance and antioxidant capacity, dried apricot fruit pieces with and without ultrasound pre-treatment were examined for physical properties such as rehydration, color, dry matter, water activity, pH and titratable acidity. Significant differences were observed between dried apricot samples, which were subjected to ultrasound pre-treatment and not, and it was concluded that apricots subjected to ultrasound pre-treatment and dried with a combination of microwavehot air were resulted with the best samples in terms of physicochemical properties. As a result of the study, it has been determined that ultrasound pre-treatment is a promising process for better preservation of fruit quality in dried apricots. [ABSTRACT FROM AUTHOR]

Copyright of Journal of Agriculture & Nature / Kahramanmaraş Sütçü İmam Üniversitesi Tarım & Doğa Dergisi is the property of Kahramanmaras Sutcu Imam Universitesi and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Bu çalışmada Kastamonu merkez köylerinde yetiştirilerek Tarhana yapımında kullanılması için yöre pazarlarında satılan kurutulmuş tohumlu darak dalı (Dereotu=Anethum graveolens L.) ve tohumlu fesleğen (Ocimum basilicum) dallarının toplam fenolik bileşik, toplam flavonoid madde ve toplam antioksidan kapasiteleri belirlenmiştir. Tohumlar ve saplar ayrı ayrı analiz edilmiştir. Darak dalında ortalama toplam fenolik bileşik, toplam flavonoid madde ve toplam antioksidan kapasiteleri sırasıyla 2,89 mg gallik asit eşdeğeri/g tohum,3,28 mg gallik asit eşdeğeri/g sap;7,38mg kuersetin eşdeğeri/g tohum, 8,85mg kuersetin eşdeğeri/g sap ve 7,03 mg askorbik asit eşdeğeri /g tohum,8,48 mg askorbik asit eşdeğeri/g sap olarak bulunmuştur. Fesleğen tohumlarının ve saplarının ortalama toplam fenolik bileşik, toplam flavonoid madde ve toplam antioksidan kapasiteleri ise sırasıyla,5,19 mg gallik asit eşdeğeri/g tohum, 4,11 mg gallik asit eşdeğeri/g sap; 9,84 mg kuersetin eşdeğeri/g tohum, 6,02 mg kuersetin eşdeğeri/g sap ve 8,30 mg askorbik asit eşdeğeri/g tohum, 7,92 mg askorbik asit eşdeğeri/g sap olarak belirlenmiştir. İlginç olarak fesleğen saplarındaki toplam fenolik bileşik, toplam flavonoid madde ve toplam antioksidan kapasite miktarlarının tohumlarından az olduğu tespit edilmişken, darak dalı saplarındaki bu maddelerin miktarları tohumlarından fazla bulunmuştur. Bu sonuçta Kastamonu tarhanasına darak dalının sapıyla birlikte katılmasının ne kadar doğru olduğunu göstermiştir.

Bu çalışmada Türkiye’de üretilen konvansiyonel ve organik çiğ sütlerin bazı fizikokimyasal özellikleri, yağ asitleri kompozisyonu ve antioksidan kapasitesi üzerine çiftlik üretim tipinin (konvansiyonel ve organik) ve süt toplama zamanın etkisinin ortaya konulması amaçlanmıştır. Araştırmada organik ve konvansiyonel çiftliklerden bir yıl boyunca iki ayda bir 9’ar adet çiğ süt örnekleri toplanmıştır. Organik ve konvansiyonel olarak üretilen sütlerin yağ asidi kompozisyonu, antioksidan kapasitesi, toplam fenolik madde ve bazı fizikokimyasal özellikleri (kurumadde, yağ, protein, kül, titrasyon asitliği (% laktik asit), pH, özgül ağırlık) incelenmiştir. Araştırma sonuçlarına göre konvansiyonel ve organik süt örneklerinin ortalama kurumadde, yağ, protein, kül, özgül ağırlık, asitlik ve pH değerleri sırayısla %12,06-11,97, %3,67-3,50, %3,33-3,34, %0,67-0,66, 1,0381-1,0381 g mL-1, %0,18-0,16 6,67-6,73 olarak belirlenmiştir. Konjuge linoleik asit oranlarının organik sütlerde %1,39 ile %2,87 arasında, konvansiyonel sütlerde %1,67 ile %2,96 arasında değiştiği belirlenmiştir. Sonuç olarak, süt bileşenlerini (kurumadde, yağ, protein ve kül), yağ asidi kompozisyonunu, EC50 ve toplam fenolik madde değerlerinin çiftlik üretim tipinden etkilenmediği ortaya konulmuştur. Diğer taraftan süt yağı, protein, yağ asidi oranları (oleik asit hariç), EC50, inhibisyon ve toplam fenolik madde değerlerinin toplama zamanına bağlı olarak önemli değişimler gösterdiği belirlenmiştir.

In the present study, antimicrobial and antioxidant properties of methanol extracts of some packaged and unpackaged spices including cinnamon (Cinnamomum zeylanicum), cumin (Cuminum cyminum L.), thyme (Thymus vulgaris L.) and mint (Mentha spicata L.) were determined. The antimicrobial effect of different concentrations of these spice extracts was examined by agar diffusion method against Escherichia coli, Enterococcus faecalis, Bacillus cereus, Pseudomonas aeruginosa and Salmonella typhimurium. While the antioxidant properties of spice extracts were examined using 2,2'-azino-bis-3- ethylbenzthiazoline-6-sulphonic acid (ABTS) and 2,2-diphenyl-1-picryl-hydrazyl (DPPH) methods, the total phenolic components were examined using Folin-Ciocalteu method. Methanol extracts of spices showed antimicrobial activity at different rates against tested microorganisms. The methanol extract of unpackaged mint showed highest inhibiton zones (22.50 mm) against Salmonella typhimurium. When the total phenolic concentrations of spice extracts ranged from 6239.58 to 27197.92 mg GAE/kg, the ABTS values ranged from 40.75 to 667.57 mmol Trolox/g dried spice and the percentage of DPPH inhibitions ranged from 88.98 to 96.26%. [ABSTRACT FROM AUTHOR]

Copyright of Ege Journal of Fisheries & Aquatic Sciences (EgeJFAS) / Su Ürünleri Dergisi is the property of Ege Journal of Fisheries & Aquatic Sciences (EgeJFAS) / Su Urunleri Dergisi and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Kombucha is a fermented beverage obtained by the fermentation of tea extracts containing sugar by the symbiotic culture of acetic acid bacteria and yeasts. The consumption and studies about the Kombucha are increasing steadily. In this study, caper buds belonging to Capparis ovata Desf. obtained from the Artvin region in Turkey were utilized in Kombucha production; caper buds and Kombucha tea samples (KC1: Green-tea, KC2: Caper bud, KC3: Caper bud + Green-tea) were analyzed. The dry matter, water-soluble dry matter, ash and total acidity and pH of caper buds used in Kombucha tea production were determined as 25.99±1.12 g/100g, 14.47±0.21, 1.74±0.06 g/100g, 0.57±0.06 g/100g and 5.30±0.12, respectively. In Kombucha samples, at the end of fermentation, the total acidity ranged from 0.74±0.02 to 1.43±0.04 g/100g, while the pH was between 3.18±0.01 and 3.19±0.01. Although, caper buds did not contain any anthocyanin, KC1 sample had 2.30 mg/L (cyanidin-3-glycoside equivalent) anthocyanin and it increased by 52% and determined as 3.50 mg/L (cyanidin-3-glycoside equivalent) in KC3 sample by the inclusion of caper buds. In order to determine the potential of Kombucha tea samples on health, antioxidant capacity of samples were determined, and green tea and caper bud containing KC3 sample had the highest values in extractable (TEACABTS: 7.06 μmole Trolox/mL; TEACDPPH: 7.12 μmole Trolox/mL), hydrolyzable (TEACABTS: 7.59 μmole Trolox/mL; TEACCUPRAC: 4.28 μmole Trolox/mL; TEACDPPH: 3.03 μmole Trolox/mL) and bioaccessible phenolics (TEACABTS: 5.70 μmole Trolox/mL; TEACCUPRAC: 4.47 μmole Trolox/mL; TEACDPPH: 2.36 μmole Trolox/mL). In addition, according to sensory evaluation results, KC3 with 5.61 points was the most preferred sample by panelists (overall acceptability). As a result of the study, antioxidant capacity and total phenolic component contents of tea samples were enriched by using a phenolic compond rich substrate capers buds, and a new healthy fermented beverage was produced. [ABSTRACT FROM AUTHOR]

In this study, components having antioxidant properties were extracted by microwave assisted homogenization process from artichoke leaves which are considered as a food waste. Antioxidant capacity, total phenolic and total flavonoid content analyzes were applied to the obtained extracts. Extraction yields were determined by proportioning the antioxidant capacity of the extract obtained as a result of the microwave assisted homogenization processes to the those which were obtained by Soxhlet extraction. To achieve the highest extraction yield for the microwave assisted homogenization, the optimum conditions were determined using D-optimal design by 'desirability' function approach. According to the optimization results, the highest extraction yield was predicted as 95.91% with an application of 17.13 minutes of homogenization time, 180 W of microwave power and 11200 rpm of homogenization rate. According to the verification tests, there was no statistical difference between the experimental (96.08±0.83%) and the estimated data (95.91%) (P>0.05). [ABSTRACT FROM AUTHOR]

Copyright of Yuzuncu Yil Universitesi Journal of Agricultural Sciences (YYU J Agr Sci) is the property of Yuzuncu Yil University and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

In this study, boiling and steaming pretreatments applied on artichoke slices and then dried by using vacuumassisted dryer (70°C with 10, 15 and 25 kPa) to determine the drying characteristics, color analysis, total phenolic content and antioxidant capacity. Color values showed differences according to pretreatments and drying conditions. In comparison to the fresh sample, the dried samples showed an important decrease in both antioxidant capacity and total phenolic content. The highest total phenolic content of vacuum dried artichoke slices (160.24±0.16 mg GA/100 g dw) was determined at 70°C-15 kPa with boiling water-treated samples. According to the drying characteristics, Page and Modified Page models were the best fitted drying models with the highest value of R2 (for both 0.9989) and the lowest values of RMSE (0.0023 for both) and χ² (0.000067). Bu çalışmada, farklı ön işlemler (suda haşlama ve buharla muamele) uygulanarak, vakumlu kurutucuda kurutulan (70°C'de 10, 15 ve 25 kPa) enginar dilimlerinin renk analizi, toplam fenolik madde içeriği, antioksidan kapasiteleri ve kurutma karakteristikleri incelenmiştir. Uygulanan ön işlemler ve kurutma parametreleri renk değerleri üzerinde farklılık oluşturmuştur. Kurutulmuş enginar dilimlerinde toplam fenolik madde içeriği ve antioksidan kapasite değerleri taze enginara kıyasla önemli oranda azalma göstermiştir. Vakum kurutma yapılan enginar dilimlerinde en yüksek toplam fenolik madde içeriği (160.24±0.16 mg GA/100 g dw) 15 kPa vakumda suda haşlama ön işlemine tabi tutulan enginar örneklerinde tespit edilmiştir. Enginar dilimlerinin kurutma karakteristikleri incelendiğinde uygulanan matematiksel modelleme sonucunda elde edilen verilere göre, en yüksek R2 değeri (0.9989), en düşük χ² (0.000067) ve RMSE (0.0023) değerleri Page ve Modifiye Page modellere ait olduğu belirlenmiştir. [ABSTRACT FROM AUTHOR]

The aim of this study is fractionation of hazelnut polyphenols and their characterization. For this aim, phenolic compounds were extracted with 80 % (v/v) acetone and loaded to column. Low molecular weight (LMW) and high molecular weight fractions (HMW) were fractionated with ethanol and acetone, respectively. Furthermore, LMW fraction was fractionated into four parts according to peaks observed at UV (280nm). FractionV had the highest contents/activities; total phenolics and condensed tannins contents were 77.9 mg gallic acid equivalent (GAE)/g extract and 227 mg catechin equivalent (CE)/g extract, respectively. Antioxidant activities of FractionV were 0.047 mg/mL IC50 value, 1.442 mmol Trolox equivalent (TE)/g extract, 307 mg FeSO4.7H2O/g extract for DPPH, ABTS and FRAP assays, respectively. As a result, it is seen that further fractionation of LMW is not needed and separation of LMW from HMW fraction is enough. HMW fraction could be utilized as a potential source of polyphenols. [ABSTRACT FROM AUTHOR]

Copyright of Journal of Agriculture & Nature / Kahramanmaraş Sütçü İmam Üniversitesi Tarım & Doğa Dergisi is the property of Kahramanmaras Sutcu Imam Universitesi and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)