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Efficient exciton dissociation at low energy offsets is key to overcoming voltage losses in organic solar cells. In this work, we developed two dimeric acceptors, i-YT and o-YT, by precisely controlling the position of an asymmetric electron-donating linker. It induced the foldamer conformation of i-YT with a para linkage (relative to the dicyano groups), while retaining the unfold conformation for o-YT. This subtle structural modification influenced the molecular assembly properties, enabled near-zero energy offset exciton dissociation and power conversion efficiencies exceeding 18 % for i-YT based organic solar cells. Detailed excitonic dynamics further revealed that the linker position critically influences three processes: the formation of delocalized singlet excited states, ultrafast charge transfer (~5 ps) in solid blends, and the suppression of exciton recombination. Additionally, devices based on i-YT demonstrated outstanding long-term stability, retaining 85 % of their initial efficiency after 1,400 hours of continuous illumination. These findings introduce a new class of dimeric acceptors that combine high efficiency with exceptional stability, offering a promising pathway toward low-energy-loss organic photovoltaics., (© 2024 Wiley-VCH GmbH.)

Currently, the study of cuproptosis focuses on the Cu 2+ -induced morphology changes in mitochondria (Mito), and the observation of the effect of endoplasmic reticulum (ER)-related Cu 2+ content on cuproptosis is relatively lacking. Herein, we have developed a hydroxyflavone (HF)-based NIR excited two-photon fluorescent probe, BHCO, that exhibits specific recognition of Cu 2+ with high resolution. BHCO-Cu 2+ (Cu2BC) can lead to DLAT protein aggregation, triggering cuproptosis. Furthermore, Cu2BC can upregulate reactive oxygen species (ROS) under 720 nm excitation, which facilitates ferroptosis. The synergistic effect of ferroptosis and cuproptosis leads to the damage of cellular mitochondria and endoplasmic reticulum, resulting in the severe death of cancer cells. We are firmly convinced that our nonlinear optical (NLO) small molecule probe for monitoring Cu 2+ could provide a valid tool for rapid tumor elimination through synergistic ferroptosis and cuproptosis.

This study aimed to elucidate how Cu 2+ influences the interaction between catechins and zein using multi-spectral and molecular modeling techniques. As a result, UV-vis spectra revealed characteristic changes, indicating chelation between catechins and Cu 2+ at a 1:1 M ratio. Fluorescence spectra further confirmed interaction through a static quenching mechanism between catechins/catechin-Cu 2+ complexes and zein. Catechins induced changes in the microenvironment and hydrophobicity surrounding the binding site of zein, whereas Cu 2+ had minimal impact on these aspects. CD spectra underscored catechins' role in altering zein's secondary structure conformation, alongside Cu 2+ . Various types of interactions (hydrophobic, hydrogen bonding, electrostatic, and van der Waals) contributed to the binding of catechins/catechin-Cu 2+ complexes with zein. Molecular modeling elucidated key residues and binding conformations, highlighting the significance of hydrophobic interactions and hydrogen bonding in their association. These findings not only deepen our understanding of catechin-Cu 2+ -zein interactions but also underscore their potential applications in the food industry., Competing Interests: Declaration of competing interest The authors declare that there is no conflict of the interest. No conflicts of interest is affirmed by the authors., (Copyright © 2024 Elsevier Ltd. All rights reserved.)

Transition metal phosphides (TMPs) show promise in water electrolysis due to their electronic structures, which activate hydrogen/oxygen reaction intermediates. However, TMPs face limitations in catalytic efficiency due to insufficient active sites, poor conductivity, and multiple intermediate steps in water electrolysis. Here, we synthesize a highly efficient bifunctional self-supported electrocatalyst, which consists of an N-doped carbon shell anchored on Fe-doped CoP/Co 2 P arrays on nickel foam (NC@Fe-Co x P/NF) using hydrothermal and phosphorization techniques. Experimental and theoretical results indicate that the modified morphology, with increased active site density and a tunable electronic structure induced by Fe doping in the CoP/Co 2 P heterostructure, leads to superior water electrolysis performance. The resulting NC@Fe 0.1 -CoP/Co 2 P/NF catalyst exhibits overpotentials of 122 mV for the hydrogen evolution reaction (HER) and 270 mV for the oxygen evolution reaction (OER) at 100 mA cm -2 . Furthermore, using NC@Fe 0.1 -CoP/Co 2 P/NF as both the cathode and anode in an alkaline electrolyzer enables the cell system to achieve 100 mA cm -2 at a voltage of 1.70 V, while maintaining long-term catalytic durability. This work may pave the way for designing self-supported, highly efficient electrocatalysts for practical water electrolysis applications., Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (Copyright © 2024 Elsevier Inc. All rights reserved.)

The rational design of material structures can be an effective approach to enhance the performance of solar-driven clean water production. In this study, a hollow structural nanofibrous membrane was developed by mimicking the hollow structure of polar bear hair using coaxial electrospinning. The shell layer consisted of carbon nanoparticles (C NPs) decorated CuO nanosheets (C@CuO), that exhibited photothermal conversion capacity. Meanwhile, the core layer containing hydrophilic polyvinylpyrrolidone (PVP) was eliminated to generate the hollow structure. The C NPs enhanced the membrane's light absorption to increase thermal energy harvesting, while the CuO nanosheets improved the membrane's wettability enhancing the water supply. Furthermore, the hollow structure limited air convection, prevented heat conduction, and minimized heat radiation, enabling heat localization to be achieved inside the membrane to suppress heat loss during evaporation. For 3.5 wt% saline water and actual dye wastewater, the C@CuO nanofibrous membrane achieved high evaporation rates of 1.36 kg·m -2 ·h -1 and 1.31 kg·m -2 ·h -1 , respectively, under 1 sun illumination. Moreover, even after continuous 6-h evaporation tests, the evaporation rate of the C@CuO membrane remained virtually unchanged, highlighting its long-term stability with regard to salt resistance in real-world applications. Additionally, the remarkable flexibility of the C@CuO membrane offers convenience during operation and guarantees dimensional stability when it is subjected to external stresses. These discoveries should inspire subsequent research on developing delicate architectural materials and exploring their potential applications in various fields, including energy generation, clean water production, and thermal insulation., Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (Copyright © 2024 Elsevier Inc. All rights reserved.)

At present, some progress has been made in developing NIR light-responsive free radical generators. However, the efficacy of theranostics continues to be hindered by tumor-associated inflammatory reactions. Hence, fulfilling the in situ release of free radicals upon NIR light excitation specifically activated by the inflammation microenvironment would be an ideal strategy for efficient inflammation eradication and tumor suppression but remains a challenge. Herein, a SO 2 (overexpressed reactive sulfur species in inflamed site)-stimulated phototheranostic agent ( CVS ) is successfully developed. Through a specific response to both endogenous and exogenous SO 2 with a low LOD (31.7 nM), CVS demonstrates the "switch on" two-photon activity as well as efficient OH· generation. Remarkably, in CVS -treated H22-tumor-bearing mice, the NIR light-activated accurate inflammation eradication and tumor suppression are accomplished. This reactive phototheranostic platform not only facilitates the quantification of SO 2 during inflammation but also renders it a potent NIR antihypoxic tumor agent.

Recent years have seen an increase in the development of functional Jiaosu products, including eco-friendly Jiaosu and antimicrobial healthcare fermentation products. As a result, research on the antibacterial activity of Jiaosu has attracted attention. In the present study, the endophytic yeast WCF016, which exhibits antibacterial activity against Escherichia coli and Staphylococcus aureus, was isolated from the peel of water chestnut and identified as Candida sake via morphological and phylogenetic analyses based on 26S rDNA D1/D2 region sequencing. Water chestnut Jiaosu with or without WCF016 inoculation exhibited similar flavor and physicochemical properties. However, inoculation significantly enhanced the antibacterial activity of water chestnut Jiaosu, especially in group D (inoculate of both fruit and vegetable enzyme starter and WCF016), which showed the largest diameter in its inhibition zone for both E. coli and S. aureus, reaching 25 ± 0 mm and 24 ± 1.0 mm. Moreover, inoculation with WCF016 influenced the abundance of the microbial community, especially Lactiplantibacillus and Zygoascus, which reached 51.76 % and 24.46 %, respectively, in group B (inoculated WCF016), thereby improving the antibacterial activity and flavor quality of the water chestnut Jiaosu. Notably, final pH, total sugar, and all organic acids effectively promoted fungal diversity and exhibited a positive correlation with most of the fungal genera. These results indicate that conditions conducive to the formation of organic acid-producing microbes and the synthesis of organic acids promote the antibacterial activity of Jiaosu., Competing Interests: Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (Copyright © 2025 Elsevier Inc. All rights reserved.)

Inflammatory Bowel Disease (IBD) is increasing worldwide and has become a global emergent disease. Probiotics have been reported to be effective in relieving colitis. Previous studies found ripened Pu-erh tea (RPT) promoted gut microbiota resilience against dextran sulfate sodium (DSS)-induced colitis in mice by increasing relative abundance of Lactobacillus. However, whether and how it alleviated DSS-induced colitis in mice need to be explored. Here, we screened a probiotic Lactobacillus johnsonii GLJ001 from feces of ripened Pu-erh tea (RPT)-administrated mice. In this study, L. johnsonii GLJ001 attenuated symptoms of DSS-induced colitis in mice, including weight loss, increased disease activity index (DAI), colon shortening and colon tissue damage, as well as high expression of inflammatory cytokines and disturbances of intestine barrier function. Furthermore, abundances of short-chain fatty acids (SCFAs)-producing bacteria (i.e. Clostridium cluster IV and XIVa, Lachnospiracea_incertae_sedis and Ruminococcus) were enhanced in the cecum of mice treated with L. johnsonii GLJ001, accompanying by an increase of SCFAs. It was also found that SCFAs inhibited mRNA expression of M1 macrophage markers (Inos and CD86), inflammatory cytokines (TNF-α and Il-1β) and SCFAs receptors (Gpr41 and Gpr43) induced by lipopolysaccharide (LPS) and interferon-γ (IFN-γ) in THP-1 cell line. Collectively, L. johnsonii GLJ001 prevented DSS-induced colitis in mice by inhibiting M1 macrophage polarization via gut microbiota-SCFAs axis, and can be administered for management of colitis., Competing Interests: Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (Copyright © 2024 Elsevier B.V. All rights reserved.)

Purpose: Dual-energy computed tomography (DECT) enables the differentiation of different materials. Additionally, DECT images consist of multiple scans of the same sample, revealing information similarity within the energy domain. To leverage this information similarity and address safety concerns related to excessive radiation exposure in DECT imaging, sparse view DECT imaging is proposed as a solution. However, this imaging method can impact image quality. Therefore, this paper presents a hybrid spectrum data generative diffusion reconstruction model (HSGDM) to improve imaging quality., Method: To exploit the spectral similarity of DECT, we use interleaved angles for sparse scanning to obtain low- and high-energy CT images with complementary incomplete views. Furthermore, we organize low- and high-energy CT image views into multichannel forms for training and inference and promote information exchange between low-energy features and high-energy features, thus improving the reconstruction quality while reducing the radiation dose. In the HSGDM, we build two types of diffusion model constraint terms trained by the image space and wavelet space. The wavelet space diffusion model exploits mainly the orientation and scale features of artifacts. By integrating the image space diffusion model, we establish a hybrid constraint for the iterative reconstruction framework. Ultimately, we transform the iterative approach into a cohesive sampling process guided by the measurement data, which collaboratively produces high-quality and consistent reconstructions of sparse view DECT., Results: Compared with the comparison methods, this approach is competitive in terms of the precision of the CT values, the preservation of details, and the elimination of artifacts. In the reconstruction of 30 sparse views, with increases of 3.51 dB for the peak signal-to-noise ratio (PSNR), 0.03 for the structural similarity index measure (SSIM), and a reduction of 74.47 for the Fréchet inception distance (FID) score on the test dataset. In the ablation study, we determined the effectiveness of our proposed hybrid prior, consisting of the wavelet prior module and the image prior module, by comparing the visual effects and quantitative results of the methods using an image space model, a wavelet space model, and our hybrid model approach. Both qualitative and quantitative analyses of the results indicate that the proposed method performs well in sparse DECT reconstruction tasks., Conclusion: We have developed a unified optimized mathematical model that integrates the image space and wavelet space prior knowledge into an iterative model. This model is more practical and interpretable than existing approaches are. The experimental results demonstrate the competitive performance of the proposed model., Competing Interests: Declaration of competing interest We declare that we have no financial and personal relationships with other people or organizations that can inappropriately influence our work, there is no professional or other personal interest of any nature or kind in any product, service and/or company that could be construed as influencing the position presented in, or the review of, the manuscript entitled, “DECT Sparse Reconstruction Based on Hybrid Spectrum Data Generative Diffusion Model”., (Copyright © 2025 Elsevier B.V. All rights reserved.)

Background: Currently, some novel rods with lower elastic modulus have the potential as alternatives to traditional titanium alloy rods in lumbar fusion. However, how the elastic modulus of the rod (rod-E) influences the biomechanical performance of lumbar interbody fusion remains unclear. This study aimed to explore the quantitative relationships between rod-E and the biomechanical performance of transforaminal lumbar interbody fusion (TLIF)., Methods: The intact finite element model of L1-S1 was constructed and validated. Then 12 TLIF models with rods of different elastic moduli (ranging from 1 GPa to 110 GPa with an interval of 10 GPa) were developed. The range of motion (ROM) of the fixed segment, mean strain of the bone graft, and maximum von Mises stresses on the cage, endplate, and posterior fixation system models were calculated. Finally, regression analysis was performed to establish functional relationships between rod-E and these indexes., Results: Increasing rod-E decreased ROM of the fixed segment, mean strain of the bone grafts, and peak stresses on the cage and endplate, while increasing peak stress on the screw-rod system. When rod-E increased from 1 GPa to 10 GPa, ROM decreased by 10.4%-39.4%. Further increasing rod-E from 10 GPa to 110 GPa resulted in a 9.3%-17.4% reduction in ROM. The peak stresses on the posterior fixation system showed a nonlinear increase as the rod-E increased from 1 GPa to 110 GPa under most loading conditions. The R 2 values for all fitting curves ranged from 0.76 to 1.00., Conclusion: The functional relationships between rod-E and the biomechanical properties of TLIF were constructed comprehensively. When the rod-E exceeds 10 GPa, further increases may not significantly improve stability, however, it may increase the risk of fixation failure. Therefore, a rod with an elastic modulus of approximately 10 GPa may provide optimal biomechanical properties for TLIF., Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest., (Copyright © 2025 Li, Du, Cao, Lu, Sun, Wei, Li and Zhang.)

Here, we report the facile synthesis of imidazole-linked porous organic cages (IPOCs) via an in situ cyclization reaction protocol. Specifically, three IPOCs with [2+4] lantern-like structures and one with a [3+6] triangular prism structure were successfully prepared through condensation reactions between tetraformyl-functionalized calix[4]arene and bis(o-phenylenediamine) monomers in a single pot. Notably, these IPOCs exhibit high porosity, with Brunauer-Emmett-Teller (BET) specific surface areas reaching up to 1162 m 2  g -1 . Moreover, they demonstrate excellent chemical stability in both strong acidic and alkaline solutions. Furthermore, IPOC-2 and IPOC-4 display a remarkable NH 3 capturing capability, with uptakes of up to 11.5 mmol g -1 at 1 bar and 298 K, surpassing most reported porous organic materials. Additionally, IPOC-1 exhibits highly efficient fluorescent quenching sensing of aqueous NH 3 , with a detection limit as low as 3.35×10 -6  M. These findings strongly suggest the potential for widespread use of imidazole linkages in the development of robust functional porous organic cage materials for diverse applications., (© 2025 Wiley-VCH GmbH.)

Sodium tripolyphosphate (STPP), as one of the many food additives, can cause gastrointestinal discomfort and a variety of adverse reactions when ingested by the human body, which is a great potential threat to human health. Therefore, it is necessary to develop a fast, sensitive and simple method to detect STPP in food. In this study, we synthesized a kind of nitrogen-doped carbon quantum dots (N-CQDs), and were surprised to find that the addition of STPP led to the gradual enhancement of the emission peaks of the N-CQDs, with a good linearity in the range of 0.067-1.96 μM and a low detection limit as low as 0.024 μM. Up to now, there is no report on the use of carbon quantum dots for the direct detection of STPP. Meanwhile, we found that the addition of Al 3+ effectively bursts the fluorescence intensity of N-CQDs@STPP solution and has a good linear relationship in the range of 0.33-6.25 μM with a lower detection limit of 0.24 μM. To this end, we developed a fluorescent probe to detect STPP and Al 3+ . In addition, the probe was successfully applied to the detection of bread samples, which has great potential for practical application., Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (Copyright © 2024 Elsevier B.V. All rights reserved.)

The treatment of antibiotic wastewater often faces the challenge of simultaneously and effectively degrading multiple components under complex conditions. To address this challenge, magnetite nanoparticles doped ultrafine activated charcoal powder (MNPs/UACP), which effectively catalyzed the decomposition of H 2 O 2 into •OH and HO 2 •, was prepared using chemical co-precipitation. Under optimum conditions (i.e., tetracycline (TC) concentration = 100 ppm, pH = 3, H 2 O 2 concentration = 4.9 mM, catalyst dosage = 0.5 g/L), the 50% MNPs/UACP-H 2 O 2 system achieved 97.5% TC removal within 180 min, driven by the synergistic action between adsorption and catalytic oxidation. The stability of 50% MNPs/UACP in recycling was evaluated through repeated reaction cycles, demonstrating that the TC removal efficiency remained at 91.0% even after five cycles. The competition among TC, oxytetracycline (OTC), and chloramphenicol (CAP) in the MNPs/UACP-H 2 O 2 system was closely related to the catalytic oxidation performance, and increasing the proportion of MNPs in MNPs/UACP to above 50% effectively reduced the competition, optimizing degradation efficiency. This study is among the first to provide a comprehensive understanding of adsorption-catalytic oxidation coupled system, offering new insights for broad environmental applications., Competing Interests: Declaration of Competing Interest ☒ The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (Copyright © 2025. Published by Elsevier Inc.)

Factors influencing inhibition of lignin on the enzymatic hydrolysis have not been fully elucidated. This study aims to elucidate the effects of lignin fractionation and condensation on its inhibition on enzymatic hydrolysis in aromatic-additive-assisted acidic pretreatment using 2-naphthol (2 N), 2-naphthol-7-sulfonate (NS), and resorcinol (RS). Through simulation reactions of pretreatment and physiochemical analyses of ethanol-extractable lignins (ELs) and cellulolytic enzyme lignins (CELs) from pretreatment, it was observed that 2 N addition in the acidic pretreatment could suppress lignin condensation. This suppression consequently mitigated inhibition of EL-AP-2 N on the enzymatic hydrolysis of Avicel. Simultaneously, addition of NS in the pretreatment can enhance lignin fractionation by facilitating decomposition of lignin into water and ethanol soluble fractions, thereby mitigating inhibition of CEL-AP-NS on the enzymatic hydrolysis. Meanwhile, with RS in the pretreatment, EL-AP-RS and CEL-AP-RS demonstrated the most pronounced inhibition among ELs and CELs. This inhibition may be attributed to the increased phenolic OH groups with the introduction of RS units. A heatmap analysis revealing relationship between lignin characteristics and its inhibition indicated that ELs exhibit reduced inhibition on enzymatic hydrolysis when lignin condensation was suppressed. Conversely, CELs would show diminished inhibitory effects when lignin particle sizes were smaller and lignin fractionation was stronger., Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (Copyright © 2025 Elsevier B.V. All rights reserved.)

In order to solve the problem of poor adaptability and robustness of the rule-based energy management strategy (EMS) in hybrid commercial vehicles, leading to suboptimal vehicle economy, this paper proposes an improved dung beetle algorithm (DBO) optimized multi-fuzzy control EMS. First, the rule-based EMS is established by dividing the efficient working areas of the methanol engine and power battery. The Tent chaotic mapping is then used to integrate strategies of cosine, Lévy flight, and Cauchy Gaussian mutation, improving the DBO. This integration compensates for the traditional dung beetle algorithm's tendency to fall into local optima and enhances its global search capability. Subsequently, fuzzy controllers for the driving charging mode and hybrid driving mode are designed under this rule-based EMS. Finally, the improved DBO is used to obtain the optimal control of the fuzzy controller by taking the fuel consumption of the whole vehicle and the fluctuation change of the battery state of charge (SOC) as the optimization objectives. Compared to traditional rule-based energy management strategies, the optimized fuzzy control using the enhanced DBO continuously adjusts the torque distribution between the engine and motor based on the vehicle's real-time state, resulting in a 9.07% reduction in fuel consumption and a 3.43% decrease in battery SOC fluctuations., Competing Interests: The author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article., (Copyright: © 2025 Li et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.)

The effects of dilute acid prehydrolysate from poplar were investigated and compared in the enzymatic hydrolysis, fermentation, and simultaneous saccharification fermentation (SSF) in this study. The improvement of enzymatic hydrolysis and fermentation with resin adsorption and surfactant addition has also been represented. A total of 16 phenolic alcohols, aldehydes, acids and 3 furan derivatives in the prehydrolysates were identified and quantified by gas chromatography/mass spectrometry (GC/MS). The degree of inhibition from the phenolic compounds (26.55%) in prehydrolysate on the enzymatic hydrolysis was much higher than carbohydrates-derived inhibitors (0.52-4.64%). Around 40% degree of inhibition was eliminated in Avicel enzymatic hydrolysis when 75% of prehydrolysates phenolic compounds were removed by resin adsorption. This showed distinguishing inhibition degrees of various prehydrolysate phenolic compounds. Inhibition of prehydrolysate on enzymatic hydrolysis was more dosage-dependent, while their suppression on the fermentation showed a more complicated mode: fermentation could be terminated by the untreated prehydrolysate, while a small number of prehydrolysate inhibitors even improved the glucose consumption and ethanol production in the fermentation. Correlated with this distinct inhibition modes of prehydrolysate, the improvement of Tween 80 addition in SSF was around 7.10% for the final ethanol yield when the glucose accumulation was promoted by 76.6%., Competing Interests: Declarations. Competing interests: The authors declare no competing interests. Ethics approval: This article does not contain any studies with animals or human participants., (© 2024. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.)

The misuse of antibiotics has led to the growing problem of multidrug-resistant (MDR) bacteria, and there is still a lack of effective antibacterial agents that can replace antibiotics. Therefore, the design and development of multifunctional nanomaterials with long-term inhibitory effects on drug-resistant bacteria are extremely challenging. In this study, a multifunctional biomimetic self-assembly system, BSA-ZnO&Quercetin, based on bovine serum albumin (BSA), ZnO, and quercetin, was established using a simple and controllable method. The prepared self-assembly system has high stability and biocompatibility, and could fully combine the performance advantages of each component. BSA-ZnO&Quercetin showed excellent broad-spectrum antibacterial activity without inducing bacterial resistance. The related antibacterial mechanism of BSA-ZnO&Quercetin primarily involves biofilm inhibition and destruction, and inducing the production of reactive oxygen species, resulting in the death of the bacteria. The biomimetic self-assembly system BSA-ZnO&Quercetin constructed in this research is expected to replace antibiotics for antibacterial application., Competing Interests: Declaration of competing interest We declare that we have no financial and personal relationships with other people or organizations that can inappropriately influence our work, there is no professional or other personal interest of any nature or kind in any product, service and/or company that could be construed as influencing the position presented in, or the review of, the manuscript entitled “Construction of BSA-ZnO&Quercetin based multifunctional bionic self-assembly system and their antibacterial mechanism study”., (Copyright © 2024 Elsevier B.V. All rights reserved.)

Water purification has always been a critical yet challenging issue. In this study, an organic-inorganic composite membrane was developed using 2,2,6,6-tetramethylpiperidine-1-oxyl radical (TEMPO)-oxidized bacterial cellulose (BC) nanofibers and hydroxyapatite nanowires (HAPNW) with tunable wettability for advanced membrane separation applications. The resulting free-standing TEMPO-BC/HAPNW filter membrane exhibited strong mechanical strength, high flexibility, exceptional deformability, and a high pure water flux of up to 800 L·m -2 ·h -1 due to its porous architecture and inherent hydrophilicity. Additionally, the filter membrane demonstrated long-term high rejection efficiency towards TiO 2 nanoparticles and methylene blue through size exclusion and electrostatic interaction. Notably, the surface wettability of the composites switched to being hydrophobic and lipophilic after in situ modification, enabling superior separation of various organic solvents and oils while maintaining cycle stability. This work presents a novel biomass-derived filter membrane for efficient and sustainable wastewater treatment with high performance, easy scale-up, and green regeneration., Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this article., (Copyright © 2024. Published by Elsevier B.V.)

The quantity of cable conductors is a crucial parameter in cable manufacturing, and accurately detecting the number of conductors can effectively promote the digital transformation of the cable manufacturing industry. Challenges such as high density, adhesion, and knife mark interference in cable conductor images make intelligent detection of conductor quantity particularly difficult. To address these challenges, this study proposes the YOLO-cable model, which is an improvement made upon the YOLOv10 model. Specifically, the Focal loss function is introduced, the C2F structure in the backbone is optimized, the Focal NeXt module is added, and a multi-scale feature (MSF) module is incorporated in the Neck section. Comparative experiments with various YOLO series models demonstrate that the YOLO-cable model significantly outperformed the baseline YOLOv10s model as it achieves recall, mAP0.5, and mAP scores of 0.982, 0.994, and 0.952, respectively. Further visualization analysis shows that the overlap of YOLO-cable detection boxes with manually labeled samples reaches 90.9% in length and 95.7% in height, indicating high data consistency. The IOU threshold adopted by the model enables it to effectively filter out false detection, thus ensuring detection accuracy. In short, the proposed model excels in detecting the number of cable conductors, enhancing quality control in cable production. This study provides new insights and technical support for the application of deep learning in industrial inspections., Competing Interests: Declarations. Competing interests: The authors declare no competing interests., (© 2024. The Author(s).)

The rapid propagation of information in the digital epoch has brought a surge of rumors, creating a significant societal challenge. While prior research has primarily focused on the psychological aspects of rumors-such as the beliefs, behaviors, and persistence they evoke-there has been limited exploration of how rumors are processed in the brain. In this study, we experimented to examine both behavioral responses and EEG data during rumor detection. Participants evaluated the credibility of 80 randomly presented rumors, and only 22% were able to identify false rumors more accurately than by random chance. Our ERP findings reveal that truth judgments elicit stronger negative ERP responses (N400) compared to false judgments, while false judgments are associated with larger positive ERP responses (P2, P3, and LPP). Additionally, we identified gender differences in brain activity related to rumor detection, suggesting distinct cognitive strategies. Men demonstrated greater P2 and enhanced N400 responses, while women exhibited larger P3 and LPP amplitudes. This study is among the first to investigate the neural patterns underlying rumors recognition and to highlight gender disparities in decision-making related to rumors., Competing Interests: Declarations. Competing interests: The authors declare no competing interests. Ethics approval and consent to participate: All participants of the study provided written informed consent. All authors disclose no actual or potential conflicts of interest including any financial, personal, or other relationships with other people or organizations that could inappropriately influence (bias) their work. The study was approved by the Ethics Committee of Institute of Neuroscience and Cognitive Psychology of Anhui Polytechnic University (AHPU-SEM-2021-002)., (© 2024. The Author(s).)

Zeolite membranes are considered ideal inorganic membrane materials for separating mixtures with molecular-level differences. However, their complex preparation process with excessive synthesis solutions for traditional hydrothermal heating methods leads to various drawbacks. Here, we describe a membrane preparation strategy involving an in situ interfacial transformation of the protomembrane without solvents. Inexpensive clay powder forms the protomembrane, and the active ingredients subsequently migrate from the interior of this protomembrane to its surface and transform into a zeolite layer. Ultimately, the protomembrane is calcined to obtain the support-layer integrated zeolite membrane. Systematic research shows that clay not only serves as a raw material for the support but also provides active ingredients for the growth of zeolite crystals; thus, zeolite membranes with zeolite particles inserted into the support are formed. The zeolite membrane calcined at 800 °C possesses a p-xylene/o-xylene separation factor approaching 6263 with a permeation flux of 1.21×10 -7  mol ⋅  m -2  ⋅  s -1  ⋅  Pa -1 . This interfacial transformation method can be applied to other membranes and promote the development of membrane separation technology., (© 2024 Wiley-VCH GmbH.)

In the polymerization-induced chiral self-assembly (PICSA) process, chiral functional monomers undergo spontaneous supramolecular self-assembly and asymmetric stacking during living polymerization, leading to the in situ generation of chiroptical polymer assemblies characterized by diverse morphologies. The PICSA strategy facilitates precise control and manipulation of both non-covalent supramolecular helices and covalent macromolecular helices within aggregated cores, thereby driving significant advancements in fields such as chiral recognition materials, asymmetric catalysts, nonlinear optical materials, and ferroelectric liquid crystals (LC). This minireview summarizes recent developments in the in situ chiroptical construction and modulation associated with the PICSA methodology. Furthermore, it seeks to elucidate emerging PICSA systems founded on various living polymerization mechanisms, exploring hierarchical chirality transfer processes and the pathway complexities in both equilibrium and non-equilibrium conditions. This minireview also presents several illustrative examples that demonstrate the practical applications of chiral polymer materials synthesized through the PICSA approach, thereby illuminating future opportunities in this innovative field., (© 2024 Wiley-VCH GmbH.)

An electrochemical tandem cyclization of enaminones with amidines has been reported for the first time using dibromomethane as an initiating agent in an undivided cell. Following this protocol, a vast variety of polysubstituted 5-acylimidazoles were obtained in moderate to good yields without the use of external oxidants. Mechanistic studies indicate that the bromide anion, electroreductively generated from dibromomethane, acts as a redox mediator to complete the catalytic cycle.

The interaction between colipase and lipase is known to be crucial for lipid digestion, but the roles of other factors remain unclear. This study explores the dynamics of pancreatic lipase hydrolysis facilitated by colipase, with a focus on the regulatory roles of fatty acids and calcium ions. Using computational modeling, including insights from AlphaFold 3.0, we elucidate the structural interactions essential for hydrolysis activity. The prediction highlights the significant role of calcium ions in altering the interaction between fatty acids and the lipase-colipase complex, thereby changing catalytic efficiency. We further demonstrate that slower hydrolysis rates are associated with a stronger binding affinity between colipase and oleic acid, as well as the occupation of the lipase catalytic pocket by oleic acid in the presence of calcium ions. The AlphaFold predictions provide a robust framework for experimental validation and potential applications. These findings offer deeper insights into dietary lipid digestion and highlight potential avenues for interventions addressing lipid digestion in malnutrition.

Based on a novel bio-degumming system, the effect of chitosan on the degumming effect of ramie was investigated. The degumming effect indexes before and after the addition of chitosan were assessed, and the enzyme activities (pectinase, xylanase, ligninase and cellulase) were detected. Meanwhile changes in microbial community structure were evaluated. Furthermore, the electron-donating effect of chitosan and cellulose was further simulated by Fukui function. Degumming effect indexes showed the addition of chitosan could effectively increase the breaking strength of degummed ramie (from 6.04 to 6.59 cN/dtex), reduce the fineness (from 10.06 to 8.039 dtex), so that more gums were removed (the residual gum ratio reduced from 16.55 % to 12.09 %) and more cellulose was retained in the degummed ramie (cellulose content increased from 78.01 % to 80.96 %). Enzyme activity measurements revealed that the addition of chitosan increased the activity of degumming enzymes (pectinase, xylanase and ligninase), while decreased cellulase activity. The addition of chitosan induced changes of the community structure, with an increase of degumming microorganisms and a decrease of cellulose-degrading microorganisms. According to Fukui function, chitosan has a stronger electron donating ability than cellulose, which might be one important reason for the changes in enzyme activities and community structures., Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (Copyright © 2024 Elsevier Ltd. All rights reserved.)

The fabrication of self-reporting photosensitizers (PSs), enabling real-time evaluation of the extent of elimination of cancer cells, holds significant scientific importance in the photodynamic therapy (PDT) process. To address the intrinsic challenge of the short-wavelength light source, this work proposed an innovative approach of rational design second near-infrared (NIR-II, 1000-1700 nm) light-excited fluorescent PS systems (named HOEt-PI , Me-PI , and Et-PI , respectively) through modulating aggregation and deaggregation based on assembling strategy. Therein, the suitable interplanar distance of adjacent Et-PI linked with C-H···π interactions was an idea for relieving compact π···π packing for fluorescent imaging as well as elevating the spin-orbit coupling for reactive oxygen species (ROS) generation. With ROS continuously increasing, Et-PI underwent cell membrane-to-mitochondria migration, ultimately accumulated in nucleoli, symbolizing programmed cell death, thus distinguishing dead/live cells via three-photon fluorescence imaging (excited on 1250 nm) under photogeneration ROS. Meaningfully, the three-photon fluorescence of Et-PI was triggered by RNA of nucleoli, for which the higher signal-to-noise ratio and in-depth fluorescence imaging observed cancer cellular viability. Collectively, the proposed findings presented a constructing strategy for NIR-II light-mediated self-reporting PS for guiding the PDT of deep cancerous tissue in the future.

The rational collocation and construction of multiphase composite electrode materials with ingenious structures is a key strategic to enhance the electrochemical performance of supercapacitors (SCs). Within this project, a unique Co 9 S 8 @CoAl-LDH/NF core-shell heterostructure consisting of CoAl-LDH/NF ultrathin nanosheets sturdily attached to Co 9 S 8 /NF needle-like nanorods is grown in situ on self-supported conductive substrate nickel foam (NF) by an effortless and productive multistep hydrothermal method. The construction of the core-shell structure can effectively enhance the capacitive properties as well as the mechanical strength of the material. Compared with the single-component materials Co 9 S 8 /NF (1769.6 mF cm -2 and 91.6%) and CoAl-LDH/NF (858 mF cm -2 and 85.2%), the Co 9 S 8 @CoAl-LDH/NF composites have excellent capacitance properties (5052.4 mF cm -2 ) along with exceptional capacitance retention (5000 cycles) 98.5% even after undergoing charging and discharging. Furthermore, the asymmetric SCs fabricated with Co 9 S 8 @CoAl-LDH/NF and AC/NF exhibit an energy density of 0.17 mWh cm -2 at 3.20 mW cm -2 . Therefore, the innovative core-shell heterostructure of Co 9 S 8 @CoAl-LDH/NF presented in this study holds immense practical potential as a groundbreaking electrode material in the realm of SCs.

Considering the strong electron-donating ability and the superior biocompatibility, the integration of zero-valent iron nanostructure Fe 0 (electron-reservoir) and zero-valent boron nanostructure B 0 offers great promise for fabricating novel ferroptosis nanoagents. Nevertheless, the controlled and facile synthesis of alloyed Fe 0 and B 0 nanostructure-FeB nanometallic glasses (NMGs) has remained a long-standing challenge. Herein, a complexion-reduction strategy is proposed for the controlled synthesis of FeB NMGs with greater electron donating capacity to activate the molecular oxygen for improved ferroptosis therapy. In-depth mechanism reveales that the complexion-reduction strategy effectively prevent the long-range diffusion of Fe 0 , resulting in the amorphous alloyed Fe 0 and B 0 nanostructure-FeB nanoparticles (FeB NPs). The FeB NPs display stronger electron donating capability and electron transfer rate 9.4 times higher than that of the Fe 0 NPs, which effectively activate the molecular oxygen to produce ∙O 2 - , H 2 O 2 and ∙OH. The in vitro cellular experiments confirm the FeB-ss-SiO₂ NPs (encapsulation with SiO 2 outlayer containing -S-S- bonds) demonstrates the enhanced ferroptosis. The tumor-bearing mice models shows that FeB-ss-SiO₂ NPs exhibited superior biocompatibility and tumor inhibition effect (inhibition rate of 73%), which improve the overall survival rate for 30 days post-treatment. This study will provide an innovative way to design therapeutic nanoagents for cancer treatments., (© 2024 Wiley‐VCH GmbH.)

This study investigates the effects of cold plasma (CP) treatment on peanut protein isolate (PPI), focusing on functionality, rheology, and structural modifications across various treatment times (0, 90, 180, 270, 360, and 450 s) and voltages (120, 140, and 160 kV). Key findings include a significant increase in solubility from 9.99 mg/mL to 15.98 mg/mL, as well as 161.07 % enhanced water-holding capacity (WHC) and 448.45 % oil-holding capacity (OHC). CP treatment also improved foaming capacity (FC) to 186.46 % and increased emulsion capacity (EC) and emulsion stability (ES) by 185.90 % at 160 kV. Rheological analysis showed shear-thinning behaviour, with viscosity decreasing as the shear rate increased-higher voltages (140 kV and 160 kV) further reduced viscosity, indicating lower resistance to flow. Additionally, CP-treated PPI exhibited viscoelasticity, with increased storage and loss moduli at higher frequencies, indicating greater stiffness. Spectroscopic studies demonstrated shifts in the protein's secondary structure, altering the balance among alpha-helix, beta-sheet, and random coil components, which highlights CP's role in reengineering PPI. FTIR-ATR spectra revealed reductions in the 3200-3400 cm -1 range, suggesting changes in protein backbone vibrations and hydrogen bonding. Particle size analysis showed significant increases, especially at higher voltages and longer treatment times, stabilizing after 270 s. Zeta potential assays indicated a gradual decrease in negative surface charge, suggesting enhanced protein aggregation. Overall, CP treatment significantly improves the functional and rheological properties of PPI while inducing structural changes, making it more suitable for applications in the food and pharmaceutical industries., Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (Copyright © 2024 Elsevier B.V. All rights reserved.)

Utilising renewable energy to drive the conversion of carbon dioxide into more valuable products can effectively alleviate the energy crisis and protect the environment while actively responding to the policy of "carbon peaking and carbon neutrality". Additionally, formic acid/formate is one of the most promising and commercially valuable products of the electrocatalytic CO 2 reduction reaction (ECO 2 RR) as well as a nonhazardous material for hydrogen storage. With the continuous progress in the field of electrocatalytic CO 2 reduction to formic acid/formate (ECO 2 RF), various electrocatalysts with excellent performance have been developed. In this paper, first, the reaction mechanism of ECO 2 RF is briefly summarised, and then the recent research progress for various catalysts for ECO 2 RF, including metal-based catalysts, carbon-based material catalysts, metal-organic framework catalysts, covalent organic framework catalysts, and molecular catalysts, is reviewed. Finally, the current challenges and future perspectives of ECO 2 RF are discussed and presented., Competing Interests: Declarations. Competing Interests: The authors declare no competing interests., (© 2024. The Author(s), under exclusive licence to Springer Nature Switzerland AG.)

Metal-organic frameworks (MOFs) with a large number of active sites and high porosity are considered to be good platforms for the carbon dioxide electroreduction reaction (CO 2 RR) but with confined low conductivity or low efficiency. Here, Pd-[Bmim]PF 6 /Cu-BTC with exceptional selectivity and electron-transfer ability is elaborately designed by introducing ionic liquids (ILs) into the MOFs. ILs favor promoting the overall current density of the catalysts, and the introduction of Pd atoms combined with O atoms on the catalyst surface reconfigures into strong Pd-O bonds, improving the desorption efficiency of *CO. The unique structure of the catalyst Pd-[Bmim]PF 6 /Cu-BTC leads to a significant improvement of the C 1 product with a high Faraday efficiency (FE) of 99.36%, especially for carbon monoxide (CO) with an FE of 93.18% (-1.1 V RHE ). The exceptional performance of the catalyst is verified by density functional theory (DFT) calculations, and the reduction of the free energy required by *HOCO as a key intermediate for CO production was only 0.12 eV, providing new insights to improve the electrocatalytic performance of MOF-based materials for the CO 2 RR. In this research, an effective and promising strategy that configures active sites by larger current density is proposed to enhance the efficiency of the CO 2 RR.

The electrochemical reduction of nitrogenous species (such as N 2 , NO, NO 2 - , and NO 3 - ) for urea synthesis under ambient conditions has been extensively studied due to their potential to realize carbon/nitrogen neutrality and mitigate environmental pollution, as well as provide a means to store renewable electricity generated from intermittent sources such as wind and solar power. However, the sluggish reaction kinetics and the scarcity of active sites on electrocatalysts have significantly hindered the advancement of their practical applications. Multifunctional engineering of electrocatalysts has been rationally designed and investigated to adjust their electronic structures, increase the density of active sites, and optimize the binding energies to enhance electrocatalytic performance. Here, surface engineering, defect engineering, doping engineering, and heterostructure engineering strategies for efficient nitrogen electro-reduction are comprehensively summarized. The role of each element in engineered electrocatalysts is elucidated at the atomic level, revealing the intrinsic active site, and understanding the relationship between atomic structure and catalytic performance. This review highlights the state-of-the-art progress of electrocatalytic reactions of waste nitrogenous species into urea. Moreover, this review outlines the challenges and opportunities for urea synthesis and aims to facilitate further research into the development of advanced electrocatalysts for a sustainable future., (© 2024 Wiley‐VCH GmbH.)

Exploring novel electrochemiluminescence (ECL) co-reaction accelerators to construct ultrasensitive sensing systems is a prominent focus for developing advanced ECL sensors. However, challenges still remain in finding highly efficient accelerators and understanding their promoting mechanisms. In this paper, ZIF-67@MXene nanosheet composites, with highly conductive in-plane structure and confined-stable pore/channel, are designed to act as high-efficient co-reaction accelerators and achieve a significant enhancement in the luminol-H 2 O 2 based ECL system. Mechanism investigation suggests that hydroxyl radicals (·OH) and singlet oxygen ( 1 O 2 ) can be selectively and preferentially generated on ZIF-67@MXene due to the stable and efficient absorption of ·OH and 1 O 2 , leading to a remarkable enhancement in the ECL efficiency of luminol (830%). Finally, by designing a plasmonic NH 2 -MIL-88@Pd nanozyme, an "on-off" switch immunosensor is constructed for the detection of prostate-specific antigen (PSA). Based on the multiple signal amplification effect, the linear detection range for PSA is expanded by three orders of magnitude. The detection limit is also improved from 1.44 × 10 -11 to 9.1 × 10 -13 g mL -1 . This work proposes an effective method for the preparation of highly efficient co-reaction accelerators and provides a new strategy for the sensitive detection of cancer markers., (© 2024 Wiley‐VCH GmbH.)

Ischemic preconditioning (IPC) is a strategy that may enhances endurance performance in thermoneutral environments. Exercising in the heat increases thermoregulatory and cardiovascular strain, decreasing endurance performance. The current study aimed to determine whether IPC administration improves endurance performance in the heat. In a randomized crossover design, 12 healthy subjects (V̇O 2max : 54.4 ± 8.1 mL·kg -1 ·min -1 ) underwent either IPC administration (220 mmHg) or a sham treatment (20 mmHg), then completed a moderate-intensity 6-min running (EX1) and a high-intensity time-to-exhaustion running test (EX2) in a hot environment (35 °C, 50 % RH). Cardiac function, oxygen consumption (V̇O 2 ), and core body temperature (T CORE ) were measured. During EX2, IPC administration increased the total running time in the heat compared to the sham treatment (IPC: 416.4 ± 61.9 vs. sham 389.3 ± 40.7 s, P = 0.027). IPC administration also increased stroke volume (IPC: 150.4 ± 17.5 vs. sham: 128.2 ± 11.6 ml, P = 0.008) and cardiac output (IPC: 27.4 ± 1.7 vs. sham: 25.1 ± 2.2 ml min -1 , P = 0.007) during 100% isotime of EX2. End-exercise V̇O 2 (IPC: 3.72 ± 0.85 vs. sham: 3.54 ± 0.87 L·min -1 , P = 0.017) and slow phase amplitude (IPC: 0.57 ± 0.17 vs. sham: 0.72 ± 0.22 L·min -1 , P = 0.016) were improved. When compared with the baseline period, an increase in T CORE was less in the IPC condition during EX1 (IPC: 0.18 ± 0.06 vs. sham: 0.22 ± 0.08 °C, P = 0.005) and EX2 (IPC: 0.87 ± 0.10 vs. sham: 1.03 ± 0.10 °C, P < 0.001). IPC improves high-intensity endurance performance in the heat by 6.9 %. This performance benefit could be associated with improved cardiac and thermoregulatory function engendered by IPC administration., (© Journal of Sports Science and Medicine.)

The degradation of synthetic dye wastewater is important for green chemistry and cost-effectiveness. In this study, we developed Fe 3 O 4 @C-laccase (laccase immobilized on Fe 3 O 4 @C nanoparticles) for photothermal degradation of high concentration of triphenylmethane dye wastewater. The Fe 3 O 4 @C-laccase possessed superior pH and thermal stabilities, as well as excellent tolerance to organic solvents, inhibitors, and metal ions. Laccase activity assays revealed that the activity recovery was approximately 118.2 %. Furthermore, the Fe 3 O 4 @C-laccase presented rapid and sustainable photothermal degradation capabilities to triphenylmethane dye wastewater. The initial removal efficiencies of 400 mg/L malachite green (MG), 400 mg/L brilliant green (BG), 100 mg/L crystal violet (CV), and 600 mg/L mixed dye (MG:BG:CV = 1:1:1) wastewater were approximately 99.8 %, 99.9 %, 96.4 % and 99.2 % by 60 min treatment, respectively. After undergoing 10 batches of reuse, the photothermal degradation efficiencies of the triphenylmethane dye wastewater remained consistently high, at about 99.3 %, 97.4 %, 94.0 %, and 95.1 %, respectively. The excellent photothermal degradation properties indicate that the Fe 3 O 4 @C-laccase holds promise for addressing high concentration of textile wastewater in various applications., Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (Copyright © 2024 Elsevier B.V. All rights reserved.)

Although the fiber-based triboelectric nanogenerator (F-TENG) has been recognized as one of the most promising flexible sensor systems, it is facing a challenge of balancing the performance and the processing scalability. Herein, we develop a hierarchical coaxial F-TENG possessing PU layer, Ag layer, and PA layer from the core to the outer part by an efficient and straightforward two-step braiding method. Owning a small diameter of 1 mm, the F-TENG presents a high linear sensing response, a wide working range of 5 to 150 kPa, and a quick reaction speed of around 200 ms. In addition, it shows high flexibility, cyclic washability, and superior mechanical stability. Furthermore, customizable textiles (e.g., wrist support and socks) that conform perfectly to the human body have been knitted from the F-TENGs as warps or wefts, which are able to monitor human motion signals. Together with an optimized machine learning algorithm, five human motions (stand, slow walk, normal walk, run, and jump) can be analyzed with a precision of up to 99%. In short, this work presents a scalable approach to develop customizable self-powered sensing textiles, offering an excellent wearable digital platform/system for potential motion capture/monitoring, identification, and smart-sports-related applications.

Background: Chemiluminescence (CL) analysis is a promising analytical method with advantages including easy operation, high sensitivity and simple instrument. However, the single CL mode usually suffered from poor stability and reproducibility as a result of the flash-type nature of luminescent molecules, leading to false positive or negative results in practical applications. Dual-mode detection is an advanced sensing methodology that identifies analytes through independent output signals. This approach has the ability to circumvent the inherent constraints of individual sensing modes while integrating their respective strengths, thereby yielding a synergistic enhancement in the detection system., Results: Herein, a chemiluminescence-fluorescence (FL) dual-mode analysis and imaging system is designed by constructing an atomically Fe(Ⅲ) anchored PCN-224 peroxidase-mimicking nanozyme (PCN-224/Fe(Ⅲ)) and achieve an ultrasensitive detection of Uric Acid (UA). The multifunctional PCN-224/Fe(Ⅲ) serves as a high-efficiency co-reaction promoter in the generation of reactive oxygen species (ROS) in both the CL and FL system, while also demonstrating exceptional capabilities as fluorescent nanoprobes. Ultimately, a smartphone-adopted CL imaging device was developed to achieve a visual CL detection through the design of portable paper-based chips. Besides, with the assistance of the TMB-mediated fluorescence energy resonance transfer, the fluorescent PCN-224/Fe(Ⅲ) nanoprobes exhibited good fluorescence detection performance for UA. The limit of detection was achieved as low as 2.45 × 10 -10  M and 1.99 × 10 -9  M in the CL and FL mode, respectively., Significance: This study engineered an atomically Fe(Ⅲ)- MOF-based multifunctional nanozyme and developed an innovative approach for creating CL-FL dual-mode analysis and imaging detection for UA. The proposed CL-FL dual-mode detection system not only provided a portable and sensitive method for UA detection but also offered valuable insights into the mechanism of the co-reaction promoter enhanced CL and FL analysis., Competing Interests: Declaration of competing interest The authors declare no competing financial interest., (Copyright © 2024 Elsevier B.V. All rights reserved.)