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3,946 results on '"Ammendola A"'

1. Large-scale spin-orbit photonic circuits in two dimensions

Author

Ammendola, Maria Gorizia, Di Colandrea, Francesco, Marrucci, Lorenzo, and Cardano, Filippo

Subjects
Physics - Optics, Quantum Physics
Abstract

Photonic circuits, optical platforms that connect input and output modes according to a specific map, serve as effective optical processors for both classical and quantum states of light. The number of optical elements typically scales with that of processed modes, leading to a direct correlation between system size, circuit complexity, and optical losses. Here we present a photonic circuit technology implementing large-scale unitary maps, linking a single input to hundreds of output modes in a two-dimensional compact layout. The map corresponds to the outcome of a quantum walk of structured photons, realized experimentally through light propagation in three liquid-crystal metasurfaces, having the local orientation of optic axes artificially engineered in a complex pattern. Theoretically, the walk length and the number of connected modes can be arbitrary, keeping optical losses constant. The patterns can be designed to accurately replicate multiple unitary maps. We also discuss limited reconfigurability by adjusting the overall birefringence and the relative displacement of the three optical elements. These results lay the basis for the design of low-loss photonic circuits that target a broader range of unitary maps, primarily for manipulating multi-photon states in genuinely quantum regimes.

Published
2024

2. Artificial Intelligence for the Electron Ion Collider (AI4EIC)

Author

Allaire, C, Ammendola, R, Aschenauer, E-C, Balandat, M, Battaglieri, M, Bernauer, J, Bondì, M, Branson, N, Britton, T, Butter, A, Chahrour, I, Chatagnon, P, Cisbani, E, Cline, EW, Dash, S, Dean, C, Deconinck, W, Deshpande, A, Diefenthaler, M, Ent, R, Fanelli, C, Finger, M, Fol, E, Furletov, S, Gao, Y, Giroux, J, Waduge, NC Gunawardhana, Hassan, O, Hegde, PL, Hernández-Pinto, RJ, Blin, A Hiller, Horn, T, Huang, J, Jalotra, A, Jayakodige, D, Joo, B, Junaid, M, Kalantarians, N, Karande, P, Kriesten, B, Elayavalli, R Kunnawalkam, Li, Y, Lin, M, Liu, F, Liuti, S, Matousek, G, McEneaney, M, McSpadden, D, Menzo, T, Miceli, T, Mikuni, V, Montgomery, R, Nachman, B, Nair, RR, Niestroy, J, Oregon, SA Ochoa, Oleniacz, J, Osborn, JD, Paudel, C, Pecar, C, Peng, C, Perdue, GN, Phelps, W, Purschke, ML, Rajendran, H, Rajput, K, Ren, Y, Renteria-Estrada, DF, Richford, D, Roy, BJ, Roy, D, Saini, A, Sato, N, Satogata, T, Sborlini, G, Schram, M, Shih, D, Singh, J, Singh, R, Siodmok, A, Stevens, J, Stone, P, Suarez, L, Suresh, K, Tawfik, A-N, Acosta, F Torales, Tran, N, Trotta, R, Twagirayezu, FJ, Tyson, R, Volkova, S, Vossen, A, Walter, E, Whiteson, D, Williams, M, Wu, S, Zachariou, N, and Zurita, P

Subjects
Information and Computing Sciences, Human-Centred Computing
Abstract

The Electron-Ion Collider (EIC), a state-of-the-art facility for studying the strong force, is expected to begin commissioning its first experiments in 2028. This is an opportune time for artificial intelligence (AI) to be included from the start at this facility and in all phases that lead up to the experiments. The second annual workshop organized by the AI4EIC working group, which recently took place, centered on exploring all current and prospective application areas of AI for the EIC. This workshop is not only beneficial for the EIC, but also provides valuable insights for the newly established ePIC collaboration at EIC. This paper summarizes the different activities and R&D projects covered across the sessions of the workshop and provides an overview of the goals, approaches and strategies regarding AI/ML in the EIC community, as well as cutting-edge techniques currently studied in other experiments.

Published
2024

5. Gamma-Ray Burst observations by the high-energy charged particle detector on board the CSES-01 satellite between 2019 and 2021

Author

Palma, Francesco, Martucci, Matteo, Neubüser, Coralie, Sotgiu, Alessandro, Follega, Francesco Maria, Ubertini, Pietro, Bazzano, Angela, Rodi, James, Ammendola, Roberto, Badoni, Davide, Bartocci, Simona, Battiston, Roberto, Beolè, Stefania, Bertello, Igor, Burger, William Jerome, Campana, Donatella, Cicone, Antonio, Cipollone, Piero, Coli, Silvia, Conti, Livio, Contin, Andrea, Cristoforetti, Marco, D'Angelo, Giulia, De Angelis, Fabrizio, De Donato, Cinzia, De Santis, Cristian, Diego, Piero, Di Luca, Andrea, Fiorenza, Emiliano, Gebbia, Giuseppe, Iuppa, Roberto, Lega, Alessandro, Lolli, Mauro, Martino, Bruno, Masciantonio, Giuseppe, Mergè, Matteo, Mese, Marco, Morbidini, Alfredo, Nozzoli, Francesco, Nuccilli, Fabrizio, Oliva, Alberto, Osteria, Giuseppe, Palmonari, Federico, Panico, Beatrice, Papini, Emanuele, Parmentier, Alexandra, Perciballi, Stefania, Perfetto, Francesco, Perinelli, Alessio, Picozza, Piergiorgio, Piersanti, Mirko, Pozzato, Michele, Rebustini, Gianmaria, Recchiuti, Dario, Ricci, Ester, Ricci, Marco, Ricciarini, Sergio Bruno, Russi, Andrea, Sahnoun, Zouleikha, Savino, Umberto, Scotti, Valentina, Shen, Xuhui, Sparvoli, Roberta, Tofani, Silvia, Vertolli, Nello, Vilona, Veronica, Vitale, Vincenzo, Zannoni, Ugo, Zeren, Zhima, Zoffoli, Simona, and Zuccon, Paolo

Subjects
Astrophysics - High Energy Astrophysical Phenomena
Abstract

In this paper we report the detection of five strong Gamma-Ray Bursts (GRBs) by the High-Energy Particle Detector (HEPD-01) mounted on board the China Seismo-Electromagnetic Satellite (CSES-01), operational since 2018 on a Sun-synchronous polar orbit at a $\sim$ 507 km altitude and 97$^\circ$ inclination. HEPD-01 was designed to detect high-energy electrons in the energy range 3 - 100 MeV, protons in the range 30 - 300 MeV, and light nuclei in the range 30 - 300 MeV/n. Nonetheless, Monte Carlo simulations have shown HEPD-01 is sensitive to gamma-ray photons in the energy range 300 keV - 50 MeV, even if with a moderate effective area above $\sim$ 5 MeV. A dedicated time correlation analysis between GRBs reported in literature and signals from a set of HEPD-01 trigger configuration masks has confirmed the anticipated detector sensitivity to high-energy photons. A comparison between the simultaneous time profiles of HEPD-01 electron fluxes and photons from GRB190114C, GRB190305A, GRB190928A, GRB200826B and GRB211211A has shown a remarkable similarity, in spite of the different energy ranges. The high-energy response, with peak sensitivity at about 2 MeV, and moderate effective area of the detector in the actual flight configuration explain why these five GRBs, characterised by a fluence above $\sim$ 3 $\times$ 10$^{-5}$ erg cm$^{-2}$ in the energy interval 300 keV - 50 MeV, have been detected., Comment: Accepted for publication in The Astrophysical Journal (ApJ)

Published
2023

6. Harnessing Vernacular Knowledge for Contemporary Sustainable Design through a Collaborative Digital Platform

Author

Letizia Dipasquale, Jacopo Ammendola, Lucia Montoni, Edoardo Paolo Ferrari, and Matteo Zambelli

Subjects
cultural heritage, vernacular architecture, sustainability, knowledge management, web mapping, mobile applications, Archaeology, CC1-960
Abstract

Vernacular architecture offers valuable technological and typological solutions rooted in knowledge systems that connect environmental, social, economic, and cultural contexts. This paper introduces the Heritage for People Platform, a collaborative digital tool developed under the VerSus+ project (Creative Europe Program), aimed at organising and disseminating vernacular architectural knowledge with a focus on sustainable practices that are both culturally and environmentally conscious. The platform builds upon lessons learned from similar projects, offering key improvements such as the adoption of a Case-Based Reasoning methodology, which organises examples by geographic location, materials, and intervention types. A structured classification system based on sustainability principles and strategies enables cross-disciplinary research and comparison. The design process was highly participatory, incorporating user feedback at every stage to ensure the platform is accessible to a wide range of users, including designers, scholars, craftspeople, and the general public. A cross-device, user-centered approach further broadens its accessibility. The platform provides a public, web-based geospatial repository where users can create, update, and explore a dynamic collection of artefacts, design models, people, and institutions from across the globe. This tool marks a significant advance in promoting and preserving both physical and intangible heritage, with strong educational and practical applications for sustainable architecture. The paper details the theoretical framework and real-world potential of the platform as a critical resource for promoting sustainability in the built environment.

Published
2024
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7. Artificial Intelligence for the Electron Ion Collider (AI4EIC)

Author

Allaire, C., Ammendola, R., Aschenauer, E. -C., Balandat, M., Battaglieri, M., Bernauer, J., Bondì, M., Branson, N., Britton, T., Butter, A., Chahrour, I., Chatagnon, P., Cisbani, E., Cline, E. W., Dash, S., Dean, C., Deconinck, W., Deshpande, A., Diefenthaler, M., Ent, R., Fanelli, C., Finger, M., Finger, Jr., M., Fol, E., Furletov, S., Gao, Y., Giroux, J., Waduge, N. C. Gunawardhana, Harish, R., Hassan, O., Hegde, P. L., Hernández-Pinto, R. J., Blin, A. Hiller, Horn, T., Huang, J., Jayakodige, D., Joo, B., Junaid, M., Karande, P., Kriesten, B., Elayavalli, R. Kunnawalkam, Lin, M., Liu, F., Liuti, S., Matousek, G., McEneaney, M., McSpadden, D., Menzo, T., Miceli, T., Mikuni, V., Montgomery, R., Nachman, B., Nair, R. R., Niestroy, J., Oregon, S. A. Ochoa, Oleniacz, J., Osborn, J. D., Paudel, C., Pecar, C., Peng, C., Perdue, G. N., Phelps, W., Purschke, M. L., Rajput, K., Ren, Y., Renteria-Estrada, D. F., Richford, D., Roy, B. J., Roy, D., Sato, N., Satogata, T., Sborlini, G., Schram, M., Shih, D., Singh, J., Singh, R., Siodmok, A., Stone, P., Stevens, J., Suarez, L., Suresh, K., Tawfik, A. -N., Acosta, F. Torales, Tran, N., Trotta, R., Twagirayezu, F. J., Tyson, R., Volkova, S., Vossen, A., Walter, E., Whiteson, D., Williams, M., Wu, S., Zachariou, N., and Zurita, P.

Subjects
Physics - Accelerator Physics, Computer Science - Machine Learning, High Energy Physics - Experiment, Nuclear Experiment, Nuclear Theory
Abstract

The Electron-Ion Collider (EIC), a state-of-the-art facility for studying the strong force, is expected to begin commissioning its first experiments in 2028. This is an opportune time for artificial intelligence (AI) to be included from the start at this facility and in all phases that lead up to the experiments. The second annual workshop organized by the AI4EIC working group, which recently took place, centered on exploring all current and prospective application areas of AI for the EIC. This workshop is not only beneficial for the EIC, but also provides valuable insights for the newly established ePIC collaboration at EIC. This paper summarizes the different activities and R&D projects covered across the sessions of the workshop and provides an overview of the goals, approaches and strategies regarding AI/ML in the EIC community, as well as cutting-edge techniques currently studied in other experiments., Comment: 27 pages, 11 figures, AI4EIC workshop, tutorials and hackathon

Published
2023

8. APEIRON: composing smart TDAQ systems for high energy physics experiments

Author

Ammendola, Roberto, Biagioni, Andrea, Chiarini, Carlotta, Ciardiello, Andrea, Cretaro, Paolo, Frezza, Ottorino, Cicero, Francesca Lo, Lonardo, Alessandro, Martinelli, Michele, Paolucci, Pier Stanislao, Rossi, Cristian, Simula, Francesco, Turisini, Matteo, and Vicini, Piero

Subjects
Computer Science - Distributed, Parallel, and Cluster Computing, Physics - Instrumentation and Detectors
Abstract

APEIRON is a framework encompassing the general architecture of a distributed heterogeneous processing platform and the corresponding software stack, from the low level device drivers up to the high level programming model. The framework is designed to be efficiently used for studying, prototyping and deploying smart trigger and data acquisition (TDAQ) systems for high energy physics experiments., Comment: Under review in Journal of Physics: Conference Series (ACAT 2022)

Published
2023

9. Investigation of Zur-regulated metal transport systems reveals an unexpected role of pyochelin in zinc homeostasis

Author

Valerio Secli, Emma Michetti, Francesca Pacello, Federico Iacovelli, Mattia Falconi, Maria Luisa Astolfi, Daniela Visaggio, Paolo Visca, Serena Ammendola, and Andrea Battistoni

Subjects
metal transport, metallophore, zinc transport, iron transport, Pseudomonas aeruginosa, siderophores, Microbiology, QR1-502
Abstract

ABSTRACT Limiting the availability of transition metals at infection sites serves as a critical defense mechanism employed by the innate immune system to combat microbial infections. Pseudomonas aeruginosa exhibits a remarkable ability to thrive in zinc-deficient environments, facilitated by intricate cellular responses governed by numerous genes regulated by the zinc-responsive transcription factor Zur. Many of these genes have unknown functions, including those within the predicted PA2911-PA2914 and PA4063-PA4066 operons. A structural bioinformatics investigation revealed that PA2911-PA2914 comprises a TonB-dependent outer membrane receptor and inner membrane ABC-permeases responsible for importing metal-chelating molecules, whereas PA4063-PA4066 contains genes encoding a MacB transporter, likely involved in the export of large molecules. Molecular genetics and biochemical experiments, feeding assays, and intracellular metal content measurements support the hypothesis that PA2911-PA2914 and PA4063-PA4066 are engaged in the import and export of the pyochelin-cobalt complex, respectively. Notably, cobalt can reduce zinc demand and promote the growth of P. aeruginosa strains unable to import zinc, highlighting pyochelin-mediated cobalt import as a novel bacterial strategy to counteract zinc deficiency. These results unveil an unexpected role for pyochelin in zinc homeostasis and challenge the traditional view of this metallophore exclusively as an iron transporter.IMPORTANCEThe mechanisms underlying the remarkable ability of Pseudomonas aeruginosa to resist the zinc sequestration mechanisms implemented by the vertebrate innate immune system to control bacterial infections are still far from being fully understood. This study reveals that the Zur-regulated gene clusters PA2911-2914 and PA4063-PA4066 encode systems for the import and export of cobalt-bound pyochelin, respectively. This proves to be a useful strategy to counteract conditions of severe zinc deficiency since cobalt can replace zinc in many proteins. The discovery that pyochelin may contribute to cellular responses to zinc deficiency leads to a reevaluation of the paradigm that pyochelin is a siderophore involved exclusively in iron acquisition and suggests that this molecule has a broader role in modulating the homeostasis of multiple metals.

Published
2024
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10. Avatar Surgeon, Digital Pathology and Telementoring: SICE New Technology and Training Research Group Experience.

Author

Michele Ammendola, Giuseppe Massimiliano De Luca, Francesca Vescio, Nicola de'Angelis, Valeria Zuccalà, Andrea Balla, Umberto Bracale, Ludovica Guerriero, Giovanni Laracca, Vinicio Mosca, Domenico Spoletini, Monica Ortenzi, Diego Cuccurullo, Mario Testini, Giuseppe Navarra, Gabriele Anania, Pietro Mascagni, Silvia Curcio, Giuseppe Currò, and Mohanad Al Ansari

Published
2024
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11. Avatar Surgeon, Digital Pathology and Telementoring: SICE New Technology and Training Research Group Experience

Author

Ammendola, Michele, De Luca, Giuseppe Massimiliano, Vescio, Francesca, de’Angelis, Nicola, Zuccalà, Valeria, Balla, Andrea, Bracale, Umberto, Guerriero, Ludovica, Laracca, Giovanni, Mosca, Vinicio, Spoletini, Domenico, Ortenzi, Monica, Cuccurullo, Diego, Testini, Mario, Navarra, Giuseppe, Anania, Gabriele, Mascagni, Pietro, Curcio, Silvia, Currò, Giuseppe, Al Ansari, Mohanad, Goos, Gerhard, Series Editor, Hartmanis, Juris, Founding Editor, Bertino, Elisa, Editorial Board Member, Gao, Wen, Editorial Board Member, Steffen, Bernhard, Editorial Board Member, Yung, Moti, Editorial Board Member, De Paolis, Lucio Tommaso, editor, Arpaia, Pasquale, editor, and Sacco, Marco, editor

Published
2024
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12. Experimental Co-Design with a Ludic Urban Community. The Safeguard of the Identity of Vale Do Anhangabaù as a Skateboarding Spot

Author

Ammendola, Jacopo, Masiani, Benedetta, Saavedra, Christian, Pisello, Anna Laura, Editorial Board Member, Hawkes, Dean, Editorial Board Member, Bougdah, Hocine, Editorial Board Member, Rosso, Federica, Editorial Board Member, Abdalla, Hassan, Editorial Board Member, Boemi, Sofia-Natalia, Editorial Board Member, Mohareb, Nabil, Editorial Board Member, Mesbah Elkaffas, Saleh, Editorial Board Member, Bozonnet, Emmanuel, Editorial Board Member, Pignatta, Gloria, Editorial Board Member, Mahgoub, Yasser, Editorial Board Member, De Bonis, Luciano, Editorial Board Member, Kostopoulou, Stella, Editorial Board Member, Pradhan, Biswajeet, Editorial Board Member, Abdul Mannan, Md., Editorial Board Member, Alalouch, Chaham, Editorial Board Member, Gawad, Iman O., Editorial Board Member, Nayyar, Anand, Editorial Board Member, Amer, Mourad, Series Editor, Alberti, Francesco, editor, Gallo, Paola, editor, Matamanda, Abraham R., editor, and Strauss, Eric J., editor

Published
2024
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13. HIKE, High Intensity Kaon Experiments at the CERN SPS

Author

Gil, E. Cortina, Jerhot, J., Lurkin, N., Numao, T., Velghe, B., Wong, V. W. S., Bryman, D., Bician, L., Hives, Z., Husek, T., Kampf, K., Koval, M., Akmete, A. T., Aliberti, R., Büscher, V., Di Lella, L., Doble, N., Peruzzo, L., Schott, M., Wahl, H., Wanke, R., Döbrich, B., Montalto, L., Rinaldi, D., Dettori, F., Cardini, A., Lai, A., Bomben, L., Carsi, S., Prest, M., Selmi, A., Lezzani, G., Monti-Guarnieri, P., Perna, L., Dalpiaz, P., Guidi, V., Mazzolari, A., Neri, I., Petrucci, F., Soldani, M., Bandiera, L., Ramusino, A. Cotta, Gianoli, A., Romagnoni, M., Sytov, A., Lenti, M., Panichi, I., Ruggiero, G., Bizzeti, A., Bucci, F., Antonelli, A., Di Meco, E., Lanfranchi, G., Martellotti, S., Martini, M., Moulson, M., Paesani, D., Sarra, I., Spadaro, T., Tinti, G., Vallazza, E., Ambrosino, F., Giordano, R., Massarotti, P., Napolitano, M., Saracino, G., Di Donato, C., D'Ambrosio, G., D'Errico, M., Mirra, M., Neshatpour, S., Fiorenza, R., Rosa, I., De Salvador, D., Sgarbossa, F., Anzivino, G., Germani, S., Volpe, R., Cenci, P., Cutini, S., Duk, V., Lubrano, P., Pepe, M., Piccini, M., Costantini, F., Donati, S., Giorgi, M., Giudici, S., Lamanna, G., Pedreschi, E., Pinzino, J., Sozzi, M., Fantechi, R., Giusti, V., Spinella, F., Mannelli, I., Raggi, M., Biagioni, A., Cretaro, P., Frezza, O., Cicero, F. Lo, Lonardo, A., Turisini, M., Vicini, P., Ammendola, R., Bonaiuto, V., Fucci, A., Salamon, A., Sargeni, F., Arcidiacono, R., Bloch-Devaux, B., Menichetti, E., Migliore, E., Biino, C., Marchetto, F., Baigarashev, D., Kambar, Y., Kereibay, D., Mukhamejanov, Y., Sakhiyev, S., Olvera, A. Briano, Engelfried, J., Estrada-Tristan, N., Piandani, R., Santos, M. A. Reyes, Rivera, K. A. Rodriguez, Boboc, P. C., Bragadireanu, A. M., Ghinescu, S. A., Hutanu, O. E., Blazek, T., Cerny, V., Kleimenova, A., Kucerova, Z., Santos, D. Martinez, Prouve, C., Boretto, M., Brizioli, F., Ceccucci, A., Corvino, M., Danielsson, H., Duval, F., Gamberini, E., Guida, R., Holzer, E. B., Jenninger, B., Miotto, G. Lehmann, Lichard, P., Massri, K., Minucci, E., Perrin-Terrin, M., Ryjov, V., Swallow, J., Van Dijk, M., Zamkovsky, M., Marchevski, R., Gerbershagen, A., Fry, J. R., Gonnella, F., Goudzovski, E., Henshaw, J., Kenworthy, C., Lazzeroni, C., Parkinson, C., Romano, A., Sanders, J., Shaikhiev, A., Tomczak, A., Heath, H., Britton, D., Norton, A., Protopopescu, D., Dainton, J. B., Jones, R. W. L., De Santo, A., Salvatore, F., Cooper, P., Coward, D., and Rubin, P.

Subjects
High Energy Physics - Experiment, Physics - Instrumentation and Detectors
Abstract

A timely and long-term programme of kaon decay measurements at a new level of precision is presented, leveraging the capabilities of the CERN Super Proton Synchrotron (SPS). The proposed programme is firmly anchored on the experience built up studying kaon decays at the SPS over the past four decades, and includes rare processes, CP violation, dark sectors, symmetry tests and other tests of the Standard Model. The experimental programme is based on a staged approach involving experiments with charged and neutral kaon beams, as well as operation in beam-dump mode. The various phases will rely on a common infrastructure and set of detectors., Comment: Letter of Intent submitted to CERN SPSC. Address all correspondence to hike-eb@cern.ch

Published
2022

14. A Multi-FPGA High Performance Computing System for 3D FFT-based Numerical Simulations

Author

Ammendola, Roberto

Subjects
Computer Science - Distributed, Parallel, and Cluster Computing, Physics - Computational Physics
Abstract

In the field of High Performance Computing, communications among processes represent a typical bottleneck for massively parallel scientific applications. Object of this research is the development of a network interface card with specific offloading capabilities that could help large scale simulations in terms of communication latency and scalability with the number of computing elements. In particular this work deals with the development of a double precision floating point complex arithmetic unit with a parallel-pipelined architecture, in order to implement a massively parallel computing system tailored for three dimensional Fast Fourier Transform., Comment: PhD Thesis at Department of Electrical Engineering, University of Roma Tor Vergata, year 2019

Published
2022

16. First search for K+ → π0πμe decays

Author

M.U. Ashraf, E. Cortina Gil, E. Minucci, S. Padolski, P. Petrov, A. Shaikhiev, R. Volpe, T. Numao, Y. Petrov, B. Velghe, V.W.S. Wong, D. Bryman, J. Fu, Z. Hives, T. Husek, J. Jerhot, K. Kampf, M. Kolesar, M. Zamkovsky, B. De Martino, M. Perrin-Terrin, B. Döbrich, S. Lezki, J. Schubert, A.T. Akmete, R. Aliberti, G. Khoriauli, J. Kunze, D. Lomidze, L. Peruzzo, M. Vormstein, R. Wanke, P. Dalpiaz, M. Fiorini, I. Neri, A. Norton, F. Petrucci, M. Soldani, H. Wahl, L. Bandiera, A. Cotta Ramusino, A. Gianoli, M. Romagnoni, A. Sytov, E. Iacopini, G. Latino, M. Lenti, P. Lo Chiatto, I. Panichi, A. Parenti, A. Bizzeti, F. Bucci, A. Antonelli, G. Georgiev, V. Kozhuharov, G. Lanfranchi, S. Martellotti, M. Moulson, T. Spadaro, G. Tinti, F. Ambrosino, T. Capussela, M. Corvino, M. D'Errico, D. Di Filippo, R. Fiorenza, M. Francesconi, R. Giordano, P. Massarotti, M. Mirra, M. Napolitano, I. Rosa, G. Saracino, G. Anzivino, F. Brizioli, E. Imbergamo, R. Lollini, R. Piandani, C. Santoni, M. Barbanera, P. Cenci, B. Checcucci, P. Lubrano, M. Lupi, M. Pepe, M. Piccini, F. Costantini, L. Di Lella, N. Doble, M. Giorgi, S. Giudici, G. Lamanna, E. Lari, E. Pedreschi, M. Sozzi, C. Cerri, R. Fantechi, L. Pontisso, F. Spinella, I. Mannelli, G. D'Agostini, M. Raggi, A. Biagioni, P. Cretaro, O. Frezza, E. Leonardi, A. Lonardo, M. Turisini, P. Valente, P. Vicini, R. Ammendola, V. Bonaiuto, A. Fucci, A. Salamon, F. Sargeni, R. Arcidiacono, B. Bloch-Devaux, M. Boretto, E. Menichetti, E. Migliore, D. Soldi, C. Biino, A. Filippi, F. Marchetto, A. Briano Olvera, J. Engelfried, N. Estrada-Tristan, M.A. Reyes Santos, K.A. Rodriguez Rivera, P. Boboc, A.M. Bragadireanu, S.A. Ghinescu, O.E. Hutanu, L. Bician, T. Blazek, V. Cerny, Z. Kucerova, T. Velas, J. Bernhard, A. Ceccucci, M. Ceoletta, H. Danielsson, N. De Simone, F. Duval, L. Federici, E. Gamberini, L. Gatignon, R. Guida, F. Hahn, E.B. Holzer, B. Jenninger, M. Koval, P. Laycock, G. Lehmann Miotto, P. Lichard, A. Mapelli, K. Massri, M. Noy, V. Palladino, J. Pinzino, V. Ryjov, S. Schuchmann, S. Venditti, X. Chang, A. Kleimenova, R. Marchevski, T. Bache, M.B. Brunetti, V. Duk, V. Fascianelli, J.R. Fry, F. Gonnella, E. Goudzovski, J. Henshaw, L. Iacobuzio, C. Kenworthy, C. Lazzeroni, N. Lurkin, F. Newson, C. Parkinson, A. Romano, J. Sanders, A. Sergi, A. Sturgess, J. Swallow, A. Tomczak, H. Heath, R. Page, S. Trilov, B. Angelucci, D. Britton, C. Graham, D. Protopopescu, J. Carmignani, J.B. Dainton, R.W.L. Jones, G. Ruggiero, L. Fulton, D. Hutchcroft, E. Maurice, B. Wrona, A. Conovaloff, P. Cooper, D. Coward, P. Rubin, A. Baeva, D. Baigarashev, V. Bautin, D. Emelyanov, T. Enik, V. Falaleev, S. Fedotov, K. Gorshanov, E. Gushchin, V. Kekelidze, D. Kereibay, S. Kholodenko, A. Khotyantsev, A. Korotkova, Y. Kudenko, V. Kurochka, V. Kurshetsov, L. Litov, D. Madigozhin, M. Medvedeva, A. Mefodev, M. Misheva, N. Molokanova, S. Movchan, V. Obraztsov, A. Okhotnikov, A. Ostankov, I. Polenkevich, Yu. Potrebenikov, A. Sadovskiy, K. Salamatin, V. Semenov, S. Shkarovskiy, V. Sugonyaev, O. Yushchenko, and A. Zinchenko

Subjects
Physics, QC1-999
Abstract

The first search for the lepton number violating decay K+→π0π−μ+e+ and lepton flavour violating decays K+→π0π+μ−e+, K+→π0π+μ+e− has been performed using a dataset collected by the NA62 experiment at CERN in 2016–2018. Upper limits of 2.9×10−10, 3.1×10−10 and 5.0×10−10, respectively, are obtained at 90% CL for the branching ratios of the three decays on the assumption of uniform phase-space distributions.

Published
2024
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19. RED-SEA Project: Towards a new-generation European interconnect

Author

Gomez, Maria Engracia, Sahuquillo, Julio, Biagioni, Andrea, Chrysos, Nikos, Berton, Damien, Frezza, Ottorino, Lo Cicero, Francesca, Lonardo, Alessandro, Martinelli, Michele, Paolucci, Pier Stanislao, Pastorelli, Elena, Simula, Francesco, Turisini, Matteo, Vicini, Piero, Ammendola, Roberto, Chiarini, Carlotta, De Luca, Chiara, Capuani, Fabrizio, Castelló, Adrián, Duro, Jose, Stabile, Eugenio, Quintana, Enrique, Bernier-Bruna, Pascale, Chen, Claire, Lagadec, Pierre-Axel, Pichon, Gregoire, Walter, Etienne, Katevenis, Manolis, Bartzis, Sokratis, Mousouros, Orestis, Xirouchakis, Pantelis, Mageiropoulos, Vangelis, Gianioudis, Michalis, Loukas, Harisis, Ioannou, Aggelos, Kallimanis, Nikos, de la Rosa, Miguel Sanchez, Gomez-Lopez, Gabriel, Alfaro-Cortés, Francisco, Sahuquillo, Jesus Escudero, Garcia, Pedro Javier, Quiles, Francisco J., Sanchez, Jose L., De Gassowski, Gaetan, Hautreaux, Matthieu, Mathieu, Stephane, Moreau, Gilles, Perache, Marc, Taboada, Hugo, Hoefler, Torsten, Schneider, Timo, Barnaba, Matteo, Brandino, Giuseppe Piero, De Giorgi, Francesco, Poggi, Matteo, Mavroidis, Iakovos, Papaefstathiou, Yannis, Tampouratzis, Nikolaos, Kalisch, Benjamin, Krackhardt, Ulrich, Nuessle, Mondrian, Frings, Wolfang, Gottwald, Dominik, Guimaraes, Felime, Holicki, Max, Marx, Volker, Muller, Yannik, Clauss, Carsten, Falter, Hugo, Huang, Xu, Barillao, Jennifer Lopez, Moschny, Thomas, and Pickartz, Simon

Published
2024
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20. Progress report on the online processing upgrade at the NA62 experiment

Author

Turisini, M., Ammendola, R., Biagioni, A., Ciardiello, A., Cretaro, P., Frezza, O., Lamanna, G., Cicero, F. Lo, Lonardo, A., Martinelli, M., Piandani, R., Soldi, D., and Vicini, P.

Subjects
Physics - Instrumentation and Detectors, High Energy Physics - Experiment
Abstract

A new FPGA-based low-level trigger processor has been installed at the NA62 experiment. It is intended to extend the features of its predecessor due to a faster interconnection technology and additional logic resources available on the new platform. With the aim of improving trigger selectivity and exploring new architectures for complex trigger computation, a GPU system has been developed and a neural network on FPGA is in progress. They both process data streams from the Ring Imaging Cherenkov detector of the experiment to extract in real time high level features for the trigger logic. Description of the systems, latest developments and design flows are reported in this paper., Comment: 5 pages, 3 figures, 1 table. Submitted to JINST as part of the TWEPP2021 conference proceeding (Topical Workshop on Electronics for Particle Physics, 20 - 24 September, 2021, online)

Published
2022

21. Architectural improvements and technological enhancements for the APEnet+ interconnect system

Author

Ammendola, R., Biagioni, A., Frezza, O., Lonardo, A., Cicero, F. Lo, Martinelli, M., Paolucci, P. S., Pastorelli, E., Rossetti, D., Simula, F., Tosoratto, L., and Vicini, P.

Subjects
Physics - Computational Physics, Computer Science - Hardware Architecture
Abstract

The APEnet+ board delivers a point-to-point, low-latency, 3D torus network interface card. In this paper we describe the latest generation of APEnet NIC, APEnet v5, integrated in a PCIe Gen3 board based on a state-of-the-art, 28 nm Altera Stratix V FPGA. The NIC features a network architecture designed following the Remote DMA paradigm and tailored to tightly bind the computing power of modern GPUs to the communication fabric. For the APEnet v5 board we show characterizing figures as achieved bandwidth and BER obtained by exploiting new high performance ALTERA transceivers and PCIe Gen3 compliancy.

Published
2022
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22. Group brief cognitive behavioral therapy for suicide prevention compared to dialectal behavior therapy skills group for military service members: a study protocol of a randomized controlled trial

Author

Justin C. Baker, Shawna Grover, Laura H. Gunn, Cindy Charles, Heather Rikli, Michael J. Franks, Lauren R. Khazem, Sean Williams, Ennio Ammendola, Cherita Washington, Marquita Bennette, Austin Starkey, Kelly Schnecke, Shannon Cain, Craig J. Bryan, and Robert J. Cramer

Subjects
Military, Group therapy, Suicide prevention, Emotion regulation, Coping self-efficacy, Cognitive-behavioral therapy, Psychiatry, RC435-571
Abstract

Abstract Background Suicide is a pressing matter for the military. Not only does it pose a health risk, but suicide also compromises operational readiness. Despite provision of suicide prevention clinical best practices, the Department of Defense suffers several challenges (e.g., clinician shortages) limiting the agency’s ability to effectively respond to service member suicide. Implementation of evidence-based suicide-specific group therapy is a possible solution to service member well-being needs and system challenges. Service members can also gain coping skills useful beyond managing suicidal thoughts and behaviors. Methods This 2-arm non-inferiority randomized controlled trial compares a group therapy format of Brief Cognitive Behavioral Therapy (i.e., G-BCBT) with Dialectical Behavior Therapy (DBT) Skills Group. Both therapies are delivered in-person at a United States Naval Medical Center. Participants (N = 136) are active-duty service members with recent suicidal thoughts or suicidal behavior. Evaluation features electronically delivered questionnaires at baseline, after each treatment session, and at 3- and 6-month follow-up. Discussion The primary outcome concerns G-BCBT impacts on suicidal ideation. Secondary outcomes of interest are suicide attempt, psychological distress (e.g., symptoms of depression, anxiety), and self-regulatory skills (e.g., emotion regulation). We also examine self-regulatory skills as treatment moderators. Clinical trial strengths and limitations are reviewed. Trial registration This study was registered at Clinicaltrials.gov (protocol NCT05401838).

Published
2023
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26. Complications of left bundle branch area pacing compared with biventricular pacing in candidates for resynchronization therapy: Results of a propensity score–matched analysis from a multicenter registry

Author

Palmisano, Pietro, Dell’Era, Gabriele, Guerra, Federico, Ammendola, Ernesto, Ziacchi, Matteo, Laffi, Mattia, Donateo, Paolo, Guido, Alessandro, Ghiglieno, Chiara, Parlavecchio, Antonio, Dello Russo, Antonio, Nigro, Gerardo, Biffi, Mauro, Gaggioli, Germano, Senes, Jacopo, Patti, Giuseppe, Accogli, Michele, and Coluccia, Giovanni

Published
2024
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27. Author Correction: Evidence of an upper ionospheric electric field perturbation correlated with a gamma ray burst

Author

Piersanti, Mirko, Ubertini, Pietro, Battiston, Roberto, Bazzano, Angela, D’Angelo, Giulia, Rodi, James G., Diego, Piero, Zeren, Zhima, Ammendola, Roberto, Badoni, Davide, Bartocci, Simona, Beolè, Stefania, Bertello, Igor, Burger, William J., Campana, Donatella, Cicone, Antonio, Cipollone, Piero, Coli, Silvia, Conti, Livio, Contin, Andrea, Cristoforetti, Marco, De Angelis, Fabrizio, De Donato, Cinzia, De Santis, Cristian, Di Luca, Andrea, Fiorenza, Emiliano, Follega, Francesco Maria, Gebbia, Giuseppe, Iuppa, Roberto, Lega, Alessandro, Lolli, Mauro, Martino, Bruno, Martucci, Matteo, Masciantonio, Giuseppe, Mergè, Matteo, Mese, Marco, Morbidini, Alfredo, Neubüser, Coralie, Nozzoli, Francesco, Nuccilli, Fabrizio, Oliva, Alberto, Osteria, Giuseppe, Palma, Francesco, Palmonari, Federico, Panico, Beatrice, Papini, Emanuele, Parmentier, Alexandra, Perciballi, Stefania, Perfetto, Francesco, Perinelli, Alessio, Picozza, Piergiorgio, Pozzato, Michele, Rebustini, Gianmaria, Recchiuti, Dario, Ricci, Ester, Ricci, Marco, Ricciarini, Sergio B., Russi, Andrea, Sahnoun, Zuleika, Savino, Umberto, Scotti, Valentina, Shen, Xuhui, Sotgiu, Alessandro, Sparvoli, Roberta, Tofani, Silvia, Vertolli, Nello, Vilona, Veronica, Vitale, Vincenzo, Zannoni, Ugo, Zoffoli, Simona, and Zuccon, Paolo

Published
2023
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28. Group brief cognitive behavioral therapy for suicide prevention compared to dialectal behavior therapy skills group for military service members: a study protocol of a randomized controlled trial

Author

Baker, Justin C., Grover, Shawna, Gunn, Laura H., Charles, Cindy, Rikli, Heather, Franks, Michael J., Khazem, Lauren R., Williams, Sean, Ammendola, Ennio, Washington, Cherita, Bennette, Marquita, Starkey, Austin, Schnecke, Kelly, Cain, Shannon, Bryan, Craig J., and Cramer, Robert J.

Published
2023
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29. 2023 WSES guidelines for the prevention, detection, and management of iatrogenic urinary tract injuries (IUTIs) during emergency digestive surgery

Author

de’Angelis, Nicola, Schena, Carlo Alberto, Marchegiani, Francesco, Reitano, Elisa, De Simone, Belinda, Wong, Geoffrey Yuet Mun, Martínez-Pérez, Aleix, Abu-Zidan, Fikri M., Agnoletti, Vanni, Aisoni, Filippo, Ammendola, Michele, Ansaloni, Luca, Bala, Miklosh, Biffl, Walter, Ceccarelli, Graziano, Ceresoli, Marco, Chiara, Osvaldo, Chiarugi, Massimo, Cimbanassi, Stefania, Coccolini, Federico, Coimbra, Raul, Di Saverio, Salomone, Diana, Michele, Dioguardi Burgio, Marco, Fraga, Gustavo, Gavriilidis, Paschalis, Gurrado, Angela, Inchingolo, Riccardo, Ingels, Alexandre, Ivatury, Rao, Kashuk, Jeffry L., Khan, Jim, Kirkpatrick, Andrew W., Kim, Fernando J., Kluger, Yoram, Lakkis, Zaher, Leppäniemi, Ari, Maier, Ronald V., Memeo, Riccardo, Moore, Ernest E., Ordoñez, Carlos A., Peitzman, Andrew B., Pellino, Gianluca, Picetti, Edoardo, Pikoulis, Manos, Pisano, Michele, Podda, Mauro, Romeo, Oreste, Rosa, Fausto, Tan, Edward, Ten Broek, Richard P., Testini, Mario, Tian Wei Cheng, Brian Anthony, Weber, Dieter, Sacco, Emilio, Sartelli, Massimo, Tonsi, Alfredo, Dal Moro, Fabrizio, and Catena, Fausto

Published
2023
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30. Evidence of an upper ionospheric electric field perturbation correlated with a gamma ray burst

Author

Piersanti, Mirko, Ubertini, Pietro, Battiston, Roberto, Bazzano, Angela, D’Angelo, Giulia, Rodi, James G., Diego, Piero, Zeren, Zhima, Ammendola, Roberto, Badoni, Davide, Bartocci, Simona, Beolè, Stefania, Bertello, Igor, Burger, William J., Campana, Donatella, Cicone, Antonio, Cipollone, Piero, Coli, Silvia, Conti, Livio, Contin, Andrea, Cristoforetti, Marco, De Angelis, Fabrizio, De Donato, Cinzia, De Santis, Cristian, Di Luca, Andrea, Fiorenza, Emiliano, Follega, Francesco Maria, Gebbia, Giuseppe, Iuppa, Roberto, Lega, Alessandro, Lolli, Mauro, Martino, Bruno, Martucci, Matteo, Masciantonio, Giuseppe, Mergè, Matteo, Mese, Marco, Morbidini, Alfredo, Neubüser, Coralie, Nozzoli, Francesco, Nuccilli, Fabrizio, Oliva, Alberto, Osteria, Giuseppe, Palma, Francesco, Palmonari, Federico, Panico, Beatrice, Papini, Emanuele, Parmentier, Alexandra, Perciballi, Stefania, Perfetto, Francesco, Perinelli, Alessio, Picozza, Piergiorgio, Pozzato, Michele, Rebustini, Gianmaria, Recchiuti, Dario, Ricci, Ester, Ricci, Marco, Ricciarini, Sergio B., Russi, Andrea, Sahnoun, Zuleika, Savino, Umberto, Scotti, Valentina, Shen, Xuhui, Sotgiu, Alessandro, Sparvoli, Roberta, Tofani, Silvia, Vertolli, Nello, Vilona, Veronica, Vitale, Vincenzo, Zannoni, Ugo, Zoffoli, Simona, and Zuccon, Paolo

Published
2023
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31. Training curriculum in minimally invasive emergency digestive surgery: 2022 WSES position paper

Author

de’Angelis, Nicola, Marchegiani, Francesco, Schena, Carlo Alberto, Khan, Jim, Agnoletti, Vanni, Ansaloni, Luca, Barría Rodríguez, Ana Gabriela, Bianchi, Paolo Pietro, Biffl, Walter, Bravi, Francesca, Ceccarelli, Graziano, Ceresoli, Marco, Chiara, Osvaldo, Chirica, Mircea, Cobianchi, Lorenzo, Coccolini, Federico, Coimbra, Raul, Cotsoglou, Christian, D’Hondt, Mathieu, Damaskos, Dimitris, De Simone, Belinda, Di Saverio, Salomone, Diana, Michele, Espin‐Basany, Eloy, Fichtner‐Feigl, Stefan, Fugazzola, Paola, Gavriilidis, Paschalis, Gronnier, Caroline, Kashuk, Jeffry, Kirkpatrick, Andrew W., Ammendola, Michele, Kouwenhoven, Ewout A., Laurent, Alexis, Leppaniemi, Ari, Lesurtel, Mickaël, Memeo, Riccardo, Milone, Marco, Moore, Ernest, Pararas, Nikolaos, Peitzmann, Andrew, Pessaux, Patrick, Picetti, Edoardo, Pikoulis, Manos, Pisano, Michele, Ris, Frederic, Robison, Tyler, Sartelli, Massimo, Shelat, Vishal G., Spinoglio, Giuseppe, Sugrue, Michael, Tan, Edward, Van Eetvelde, Ellen, Kluger, Yoram, Weber, Dieter, and Catena, Fausto

Published
2023
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32. Measurement of the K+ → π+γγ decay

Author

E. Cortina Gil, A. Kleimenova, E. Minucci, S. Padolski, P. Petrov, A. Shaikhiev, R. Volpe, T. Numao, Y. Petrov, B. Velghe, V.W.S. Wong, D. Bryman, J. Fu, Z. Hives, T. Husek, J. Jerhot, K. Kampf, M. Zamkovsky, B. De Martino, M. Perrin-Terrin, B. Döbrich, S. Lezki, A.T. Akmete, R. Aliberti, G. Khoriauli, J. Kunze, D. Lomidze, L. Peruzzo, M. Vormstein, R. Wanke, P. Dalpiaz, M. Fiorini, A. Mazzolari, I. Neri, A. Norton, F. Petrucci, M. Soldani, H. Wahl, L. Bandiera, A. Cotta Ramusino, A. Gianoli, M. Romagnoni, A. Sytov, E. Iacopini, G. Latino, M. Lenti, P. Lo Chiatto, I. Panichi, A. Parenti, A. Bizzeti, F. Bucci, A. Antonelli, G. Georgiev, V. Kozhuharov, G. Lanfranchi, S. Martellotti, M. Moulson, T. Spadaro, G. Tinti, F. Ambrosino, T. Capussela, M. Corvino, M. D'Errico, D. Di Filippo, R. Fiorenza, R. Giordano, P. Massarotti, M. Mirra, M. Napolitano, I. Rosa, G. Saracino, G. Anzivino, F. Brizioli, E. Imbergamo, R. Lollini, R. Piandani, C. Santoni, M. Barbanera, P. Cenci, B. Checcucci, P. Lubrano, M. Lupi, M. Pepe, M. Piccini, F. Costantini, L. Di Lella, N. Doble, M. Giorgi, S. Giudici, G. Lamanna, E. Lari, E. Pedreschi, M. Sozzi, C. Cerri, R. Fantechi, L. Pontisso, F. Spinella, I. Mannelli, G. D'Agostini, M. Raggi, A. Biagioni, P. Cretaro, O. Frezza, E. Leonardi, A. Lonardo, M. Turisini, P. Valente, P. Vicini, R. Ammendola, V. Bonaiuto, A. Fucci, A. Salamon, F. Sargeni, R. Arcidiacono, B. Bloch-Devaux, M. Boretto, E. Menichetti, E. Migliore, D. Soldi, C. Biino, A. Filippi, F. Marchetto, A. Briano Olvera, J. Engelfried, N. Estrada-Tristan, M.A. Reyes Santos, K.A. Rodriguez Rivera, P. Boboc, A.M. Bragadireanu, S.A. Ghinescu, O.E. Hutanu, L. Bician, T. Blazek, V. Cerny, Z. Kucerova, J. Bernhard, A. Ceccucci, M. Ceoletta, H. Danielsson, N. De Simone, F. Duval, L. Federici, E. Gamberini, L. Gatignon, R. Guida, F. Hahn, E.B. Holzer, B. Jenninger, M. Koval, P. Laycock, G. Lehmann Miotto, P. Lichard, A. Mapelli, R. Marchevski, K. Massri, M. Noy, V. Palladino, J. Pinzino, V. Ryjov, S. Schuchmann, S. Venditti, T. Bache, M.B. Brunetti, V. Duk, V. Fascianelli, J.R. Fry, F. Gonnella, E. Goudzovski, J. Henshaw, L. Iacobuzio, C. Kenworthy, C. Lazzeroni, N. Lurkin, F. Newson, C. Parkinson, A. Romano, J. Sanders, A. Sergi, A. Sturgess, J. Swallow, A. Tomczak, H. Heath, R. Page, S. Trilov, B. Angelucci, D. Britton, C. Graham, D. Protopopescu, J. Carmignani, J.B. Dainton, R.W.L. Jones, G. Ruggiero, L. Fulton, D. Hutchcroft, E. Maurice, B. Wrona, A. Conovaloff, P. Cooper, D. Coward, P. Rubin, A. Baeva, D. Baigarashev, D. Emelyanov, T. Enik, V. Falaleev, S. Fedotov, K. Gorshanov, E. Gushchin, V. Kekelidze, D. Kereibay, S. Kholodenko, A. Khotyantsev, A. Korotkova, Y. Kudenko, V. Kurochka, V. Kurshetsov, L. Litov, D. Madigozhin, M. Medvedeva, A. Mefodev, M. Misheva, N. Molokanova, S. Movchan, V. Obraztsov, A. Okhotnikov, A. Ostankov, I. Polenkevich, Yu. Potrebenikov, A. Sadovskiy, V. Semenov, S. Shkarovskiy, V. Sugonyaev, O. Yushchenko, and A. Zinchenko

Subjects
Physics, QC1-999
Abstract

A sample of 3984 candidates of the K+→π+γγ decay, with an estimated background of 291±14 events, was collected by the NA62 experiment at CERN during 2017–2018. In order to describe the observed di-photon mass spectrum, the next-to-leading order contribution in chiral perturbation theory was found to be necessary. The decay branching ratio in the full kinematic range is measured to be (9.61±0.17)×10−7. The first search for production and prompt decay of an axion-like particle with gluon coupling in the process K+→π+a, a→γγ is also reported.

Published
2024
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33. Improved calorimetric particle identification in NA62 using machine learning techniques

Author

The NA62 collaboration, E. Cortina Gil, A. Kleimenova, E. Minucci, S. Padolski, P. Petrov, A. Shaikhiev, R. Volpe, W. Fedorko, T. Numao, Y. Petrov, B. Velghe, V. W. S. Wong, M. Yu, D. Bryman, J. Fu, Z. Hives, T. Husek, J. Jerhot, K. Kampf, M. Zamkovsky, B. De Martino, M. Perrin-Terrin, A. T. Akmete, R. Aliberti, G. Khoriauli, J. Kunze, D. Lomidze, L. Peruzzo, M. Vormstein, R. Wanke, P. Dalpiaz, M. Fiorini, A. Mazzolari, I. Neri, A. Norton, F. Petrucci, M. Soldani, H. Wahl, L. Bandiera, A. Cotta Ramusino, A. Gianoli, M. Romagnoni, A. Sytov, E. Iacopini, G. Latino, M. Lenti, P. Lo Chiatto, I. Panichi, A. Parenti, A. Bizzeti, F. Bucci, A. Antonelli, G. Georgiev, V. Kozhuharov, G. Lanfranchi, S. Martellotti, M. Moulson, T. Spadaro, G. Tinti, F. Ambrosino, T. Capussela, M. Corvino, M. D’Errico, D. Di Filippo, R. Fiorenza, R. Giordano, P. Massarotti, M. Mirra, M. Napolitano, I. Rosa, G. Saracino, G. Anzivino, F. Brizioli, E. Imbergamo, R. Lollini, R. Piandani, C. Santoni, M. Barbanera, P. Cenci, B. Checcucci, P. Lubrano, M. Lupi, M. Pepe, M. Piccini, F. Costantini, L. Di Lella, N. Doble, M. Giorgi, S. Giudici, G. Lamanna, E. Lari, E. Pedreschi, M. Sozzi, C. Cerri, R. Fantechi, L. Pontisso, F. Spinella, I. Mannelli, G. D’Agostini, M. Raggi, A. Biagioni, P. Cretaro, O. Frezza, E. Leonardi, A. Lonardo, M. Turisini, P. Valente, P. Vicini, R. Ammendola, V. Bonaiuto, A. Fucci, A. Salamon, F. Sargeni, R. Arcidiacono, B. Bloch-Devaux, M. Boretto, E. Menichetti, E. Migliore, D. Soldi, C. Biino, A. Filippi, F. Marchetto, A. Briano Olvera, J. Engelfried, N. Estrada-Tristan, M. A. Reyes Santos, P. Boboc, A. M. Bragadireanu, S. A. Ghinescu, O. E. Hutanu, L. Bician, T. Blazek, V. Cerny, Z. Kucerova, J. Bernhard, A. Ceccucci, M. Ceoletta, H. Danielsson, N. De Simone, F. Duval, B. Döbrich, L. Federici, E. Gamberini, L. Gatignon, R. Guida, F. Hahn, E. B. Holzer, B. Jenninger, M. Koval, P. Laycock, G. Lehmann Miotto, P. Lichard, A. Mapelli, R. Marchevski, K. Massri, M. Noy, V. Palladino, J. Pinzino, V. Ryjov, S. Schuchmann, S. Venditti, T. Bache, M. B. Brunetti, V. Duk, V. Fascianelli, J. R. Fry, F. Gonnella, E. Goudzovski, J. Henshaw, L. Iacobuzio, C. Kenworthy, C. Lazzeroni, N. Lurkin, F. Newson, C. Parkinson, A. Romano, J. Sanders, A. Sergi, A. Sturgess, J. Swallow, A. Tomczak, H. Heath, R. Page, S. Trilov, B. Angelucci, D. Britton, C. Graham, D. Protopopescu, J. Carmignani, J. B. Dainton, R. W. L. Jones, G. Ruggiero, L. Fulton, D. Hutchcroft, E. Maurice, B. Wrona, A. Conovaloff, P. Cooper, D. Coward, P. Rubin, A. Baeva, D. Baigarashev, D. Emelyanov, T. Enik, V. Falaleev, S. Fedotov, K. Gorshanov, E. Gushchin, V. Kekelidze, D. Kereibay, S. Kholodenko, A. Khotyantsev, A. Korotkova, Y. Kudenko, V. Kurochka, V. Kurshetsov, L. Litov, D. Madigozhin, M. Medvedeva, A. Mefodev, M. Misheva, N. Molokanova, S. Movchan, V. Obraztsov, A. Okhotnikov, A. Ostankov, I. Polenkevich, Yu. Potrebenikov, A. Sadovskiy, V. Semenov, S. Shkarovskiy, V. Sugonyaev, O. Yushchenko, and A. Zinchenko

Subjects
Fixed Target Experiments, Branching fraction, Rare Decay, Flavour Physics, Nuclear and particle physics. Atomic energy. Radioactivity, QC770-798
Abstract

Abstract Measurement of the ultra-rare K + → π + ν ν ¯ $$ {K}^{+}\to {\pi}^{+}\nu \overline{\nu} $$ decay at the NA62 experiment at CERN requires high-performance particle identification to distinguish muons from pions. Calorimetric identification currently in use, based on a boosted decision tree algorithm, achieves a muon misidentification probability of 1.2 × 10 −5 for a pion identification efficiency of 75% in the momentum range of 15–40 GeV/c. In this work, calorimetric identification performance is improved by developing an algorithm based on a convolutional neural network classifier augmented by a filter. Muon misidentification probability is reduced by a factor of six with respect to the current value for a fixed pion-identification efficiency of 75%. Alternatively, pion identification efficiency is improved from 72% to 91% for a fixed muon misidentification probability of 10 −5.

Published
2023
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34. La Depressione nell'Adulto con Disturbo dello Spettro Autistico ad alto funzionamento: Prevalenza, Fattori di Rischio, e Trattamenti: una revisione sistematica

Author

Francesco Marino 1 Angela Ammendola 1 Simona Durante 1 Salvatore Di Donna 1 Flavia Morfini 2 Rosalia Brancati 2 Marta Luongo 2 Luca Cacciapuoti 2 Marica Gallo

Subjects
disturbo dello spettro autistico, autismo ad alto funzionamento, depressione, comorbidità, età adulta, Pathology, RB1-214, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571
Abstract

Questo studio esplora la connessione tra il Disturbo dello Spettro Autistico (ASD) di livello 1 in assenza di disabilità cognitiva e la depressione negli adulti. Gli adulti con ASD hanno un rischio 4 volte maggiore rispetto alla popolazione generale di sviluppare depressione, a causa di fattori come deficit nella Teoria della Mente, isolamento sociale, disturbi del sonno e ideazione suicidaria. Mentre alcune terapie cognitivo-comportamentali e quella basata sulla mindfulness possono aiutare, le sfide diagnostiche e la sensibilità ai farmaci complicano la gestione. L'obiettivo di questa revisione sistematica è (1) valutare in che misura è diffusa la sintomatologia depressiva tra gli adulti con autismo ad alto funzionamento e (2) identificare i fattori di rischio e protettivi specifici associati allo sviluppo della depressione negli adulti con autismo ad alto funzionamento. Metodi: Questa revisione sistematica, in linea con le linee guida PRISMA, ha analizzato la comorbilità della depressione negli adulti con autismo ad alto funzionamento; alla fine della revisione sono stati inclusi 18 articoli nell’analisi. Discussioni: Gli adulti con Disturbo dello Spettro Autistico (ASD) hanno un alto rischio di depressione. La depressione può essere influenzata dai tratti autistici, complicando il quadro. Alcuni fattori di rischio includono le difficoltà nelle funzioni esecutive, problemi di Teoria della Mente e riconoscimento facciale, isolamento sociale e difficoltà sociali, disturbi del sonno e un rischio aumentato di suicidio. Sono necessarie ulteriori ricerche per comprendere i fattori protettivi e i trattamenti efficaci per la depressione in individui con ASD.

Published
2023
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35. Evidence of an upper ionospheric electric field perturbation correlated with a gamma ray burst

Author

Mirko Piersanti, Pietro Ubertini, Roberto Battiston, Angela Bazzano, Giulia D’Angelo, James G. Rodi, Piero Diego, Zhima Zeren, Roberto Ammendola, Davide Badoni, Simona Bartocci, Stefania Beolè, Igor Bertello, William J. Burger, Donatella Campana, Antonio Cicone, Piero Cipollone, Silvia Coli, Livio Conti, Andrea Contin, Marco Cristoforetti, Fabrizio De Angelis, Cinzia De Donato, Cristian De Santis, Andrea Di Luca, Emiliano Fiorenza, Francesco Maria Follega, Giuseppe Gebbia, Roberto Iuppa, Alessandro Lega, Mauro Lolli, Bruno Martino, Matteo Martucci, Giuseppe Masciantonio, Matteo Mergè, Marco Mese, Alfredo Morbidini, Coralie Neubüser, Francesco Nozzoli, Fabrizio Nuccilli, Alberto Oliva, Giuseppe Osteria, Francesco Palma, Federico Palmonari, Beatrice Panico, Emanuele Papini, Alexandra Parmentier, Stefania Perciballi, Francesco Perfetto, Alessio Perinelli, Piergiorgio Picozza, Michele Pozzato, Gianmaria Rebustini, Dario Recchiuti, Ester Ricci, Marco Ricci, Sergio B. Ricciarini, Andrea Russi, Zuleika Sahnoun, Umberto Savino, Valentina Scotti, Xuhui Shen, Alessandro Sotgiu, Roberta Sparvoli, Silvia Tofani, Nello Vertolli, Veronica Vilona, Vincenzo Vitale, Ugo Zannoni, Simona Zoffoli, and Paolo Zuccon

Subjects
Science
Abstract

Abstract Earth’s atmosphere, whose ionization stability plays a fundamental role for the evolution and endurance of life, is exposed to the effect of cosmic explosions producing high energy Gamma-ray-bursts. Being able to abruptly increase the atmospheric ionization, they might deplete stratospheric ozone on a global scale. During the last decades, an average of more than one Gamma-ray-burst per day were recorded. Nevertheless, measurable effects on the ionosphere were rarely observed, in any case on its bottom-side (from about 60 km up to about 350 km of altitude). Here, we report evidence of an intense top-side (about 500 km) ionospheric perturbation induced by significant sudden ionospheric disturbance, and a large variation of the ionospheric electric field at 500 km, which are both correlated with the October 9, 2022 Gamma-ray-burst (GRB221009A).

Published
2023
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36. A study of the K + → π 0 e + νγ decay

Author

The NA62 collaboration, E. Cortina Gil, A. Kleimenova, E. Minucci, S. Padolski, P. Petrov, A. Shaikhiev, R. Volpe, T. Numao, Y. Petrov, B. Velghe, V. W. S. Wong, D. Bryman, J. Fu, Z. Hives, T. Husek, J. Jerhot, K. Kampf, M. Zamkovsky, B. De Martino, M. Perrin-Terrin, A. T. Akmete, R. Aliberti, G. Khoriauli, J. Kunze, D. Lomidze, L. Peruzzo, M. Vormstein, R. Wanke, P. Dalpiaz, M. Fiorini, A. Mazzolari, I. Neri, A. Norton, F. Petrucci, M. Soldani, H. Wahl, L. Bandiera, A. Cotta Ramusino, A. Gianoli, M. Romagnoni, A. Sytov, E. Iacopini, G. Latino, M. Lenti, P. Lo Chiatto, I. Panichi, A. Parenti, A. Bizzeti, F. Bucci, A. Antonelli, G. Georgiev, V. Kozhuharov, G. Lanfranchi, S. Martellotti, M. Moulson, T. Spadaro, G. Tinti, F. Ambrosino, T. Capussela, M. Corvino, M. D’Errico, D. Di Filippo, R. Fiorenza, R. Giordano, P. Massarotti, M. Mirra, M. Napolitano, I. Rosa, G. Saracino, G. Anzivino, F. Brizioli, E. Imbergamo, R. Lollini, R. Piandani, C. Santoni, M. Barbanera, P. Cenci, B. Checcucci, P. Lubrano, M. Lupi, M. Pepe, M. Piccini, F. Costantini, L. Di Lella, N. Doble, M. Giorgi, S. Giudici, G. Lamanna, E. Lari, E. Pedreschi, M. Sozzi, C. Cerri, R. Fantechi, L. Pontisso, F. Spinella, I. Mannelli, G. D’Agostini, M. Raggi, A. Biagioni, P. Cretaro, O. Frezza, E. Leonardi, A. Lonardo, M. Turisini, P. Valente, P. Vicini, R. Ammendola, V. Bonaiuto, A. Fucci, A. Salamon, F. Sargeni, R. Arcidiacono, B. Bloch-Devaux, M. Boretto, E. Menichetti, E. Migliore, D. Soldi, C. Biino, A. Filippi, F. Marchetto, A. Briano Olvera, J. Engelfried, N. Estrada-Tristan, M. A. Reyes Santos, P. Boboc, A. M. Bragadireanu, S. A. Ghinescu, O. E. Hutanu, L. Bician, T. Blazek, V. Cerny, Z. Kucerova, J. Bernhard, A. Ceccucci, M. Ceoletta, H. Danielsson, N. De Simone, F. Duval, B. Döbrich, L. Federici, E. Gamberini, L. Gatignon, R. Guida, F. Hahn, E. B. Holzer, B. Jenninger, M. Koval, P. Laycock, G. Lehmann Miotto, P. Lichard, A. Mapelli, R. Marchevski, K. Massri, M. Noy, V. Palladino, J. Pinzino, V. Ryjov, S. Schuchmann, S. Venditti, T. Bache, M. B. Brunetti, V. Duk, V. Fascianelli, J. R. Fry, F. Gonnella, E. Goudzovski, J. Henshaw, L. Iacobuzio, C. Kenworthy, C. Lazzeroni, N. Lurkin, F. Newson, C. Parkinson, A. Romano, J. Sanders, A. Sergi, A. Sturgess, J. Swallow, A. Tomczak, H. Heath, R. Page, S. Trilov, B. Angelucci, D. Britton, C. Graham, D. Protopopescu, J. Carmignani, J. B. Dainton, R. W. L. Jones, G. Ruggiero, L. Fulton, D. Hutchcroft, E. Maurice, B. Wrona, A. Conovaloff, P. Cooper, D. Coward, P. Rubin, A. Baeva, D. Baigarashev, D. Emelyanov, T. Enik, V. Falaleev, S. Fedotov, K. Gorshanov, E. Gushchin, V. Kekelidze, D. Kereibay, S. Kholodenko, A. Khotyantsev, A. Korotkova, Y. Kudenko, V. Kurochka, V. Kurshetsov, L. Litov, D. Madigozhin, M. Medvedeva, A. Mefodev, M. Misheva, N. Molokanova, S. Movchan, V. Obraztsov, A. Okhotnikov, A. Ostankov, I. Polenkevich, Yu. Potrebenikov, A. Sadovskiy, V. Semenov, S. Shkarovskiy, V. Sugonyaev, O. Yushchenko, and A. Zinchenko

Subjects
Branching fraction, Electroweak Interaction, Fixed Target Experiments, Flavour Physics, Nuclear and particle physics. Atomic energy. Radioactivity, QC770-798
Abstract

Abstract A sample of 1.3 × 105 K + → π 0 e + νγ candidates with less than 1% background was collected by the NA62 experiment at the CERN SPS in 2017–2018. Branching fraction measurements are obtained at percent relative precision in three restricted kinematic regions, improving on existing results by a factor larger than two. An asymmetry, possibly related to T-violation, is investigated with no evidence observed within the achieved precision.

Published
2023
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37. Search for dark photon decays to μ + μ − at NA62

Author

The NA62 collaboration, E. Cortina Gil, J. Jerhot, A. Kleimenova, N. Lurkin, M. Zamkovsky, T. Numao, B. Velghe, V. W. S. Wong, D. Bryman, Z. Hives, T. Husek, K. Kampf, M. Koval, B. De Martino, M. Perrin-Terrin, A. T. Akmete, R. Aliberti, L. Di Lella, N. Doble, L. Peruzzo, S. Schuchmann, H. Wahl, R. Wanke, P. Dalpiaz, A. Mazzolari, I. Neri, F. Petrucci, M. Soldani, L. Bandiera, A. Cotta Ramusino, A. Gianoli, M. Romagnoni, A. Sytov, M. Lenti, P. Lo Chiatto, R. Marchevski, I. Panichi, G. Ruggiero, A. Bizzeti, F. Bucci, A. Antonelli, V. Kozhuharov, G. Lanfranchi, S. Martellotti, M. Moulson, T. Spadaro, G. Tinti, F. Ambrosino, M. D’Errico, R. Fiorenza, R. Giordano, P. Massarotti, M. Mirra, M. Napolitano, I. Rosa, G. Saracino, G. Anzivino, F. Brizioli, P. Cenci, V. Duk, R. Lollini, P. Lubrano, M. Pepe, M. Piccini, F. Costantini, M. Giorgi, S. Giudici, G. Lamanna, E. Lari, E. Pedreschi, J. Pinzino, M. Sozzi, R. Fantechi, F. Spinella, I. Mannelli, M. Raggi, A. Biagioni, P. Cretaro, O. Frezza, A. Lonardo, M. Turisini, P. Vicini, R. Ammendola, V. Bonaiuto, A. Fucci, A. Salamon, F. Sargeni, R. Arcidiacono, B. Bloch-Devaux, E. Menichetti, E. Migliore, C. Biino, A. Filippi, F. Marchetto, D. Soldi, A. Briano Olvera, J. Engelfried, N. Estrada-Tristan, R. Piandani, M. A. Reyes Santos, P. Boboc, A. M. Bragadireanu, S. A. Ghinescu, O. E. Hutanu, T. Blazek, V. Cerny, Z. Kucerova, R. Volpe, J. Bernhard, L. Bician, M. Boretto, A. Ceccucci, M. Ceoletta, M. Corvino, H. Danielsson, F. Duval, B. Döbrich, L. Federici, E. Gamberini, R. Guida, E. B. Holzer, B. Jenninger, G. Lehmann Miotto, P. Lichard, K. Massri, E. Minucci, M. Noy, V. Ryjov, J. Swallow, J. R. Fry, F. Gonnella, E. Goudzovski, J. Henshaw, C. Kenworthy, C. Lazzeroni, C. Parkinson, A. Romano, J. Sanders, A. Sergi, A. Shaikhiev, A. Tomczak, H. Heath, D. Britton, A. Norton, D. Protopopescu, J. B. Dainton, L. Gatignon, R. W. L. Jones, P. Cooper, D. Coward, P. Rubin, A. Baeva, D. Baigarashev, D. Emelyanov, T. Enik, V. Falaleev, S. Fedotov, K. Gorshanov, E. Gushchin, V. Kekelidze, D. Kereibay, S. Kholodenko, A. Khotyantsev, A. Korotkova, Y. Kudenko, V. Kurochka, V. Kurshetsov, L. Litov, D. Madigozhin, A. Mefodev, M. Misheva, N. Molokanova, V. Obraztsov, A. Okhotnikov, I. Polenkevich, Yu. Potrebenikov, A. Sadovskiy, S. Shkarovskiy, V. Sugonyaev, and O. Yushchenko

Subjects
Beyond Standard Model, Exotics, Fixed Target Experiments, Dark Matter, Nuclear and particle physics. Atomic energy. Radioactivity, QC770-798
Abstract

Abstract The NA62 experiment at CERN, designed to study the ultra-rare decay K + → π + ν ν ¯ $$ \nu \overline{\nu} $$ , has also collected data in beam-dump mode. In this configuration, dark photons may be produced by protons dumped on an absorber and reach a decay volume beginning 80 m downstream. A search for dark photons decaying in flight to μ + μ − pairs is reported, based on a sample of 1.4 × 1017 protons on dump collected in 2021. No evidence for a dark photon signal is observed. A region of the parameter space is excluded at 90% CL, improving on previous experimental limits for dark photon masses between 215 and 550 MeV/c 2.

Published
2023
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38. 2023 WSES guidelines for the prevention, detection, and management of iatrogenic urinary tract injuries (IUTIs) during emergency digestive surgery

Author

Nicola de’Angelis, Carlo Alberto Schena, Francesco Marchegiani, Elisa Reitano, Belinda De Simone, Geoffrey Yuet Mun Wong, Aleix Martínez-Pérez, Fikri M. Abu-Zidan, Vanni Agnoletti, Filippo Aisoni, Michele Ammendola, Luca Ansaloni, Miklosh Bala, Walter Biffl, Graziano Ceccarelli, Marco Ceresoli, Osvaldo Chiara, Massimo Chiarugi, Stefania Cimbanassi, Federico Coccolini, Raul Coimbra, Salomone Di Saverio, Michele Diana, Marco Dioguardi Burgio, Gustavo Fraga, Paschalis Gavriilidis, Angela Gurrado, Riccardo Inchingolo, Alexandre Ingels, Rao Ivatury, Jeffry L. Kashuk, Jim Khan, Andrew W. Kirkpatrick, Fernando J. Kim, Yoram Kluger, Zaher Lakkis, Ari Leppäniemi, Ronald V. Maier, Riccardo Memeo, Ernest E. Moore, Carlos A. Ordoñez, Andrew B. Peitzman, Gianluca Pellino, Edoardo Picetti, Manos Pikoulis, Michele Pisano, Mauro Podda, Oreste Romeo, Fausto Rosa, Edward Tan, Richard P. Ten Broek, Mario Testini, Brian Anthony Tian Wei Cheng, Dieter Weber, Emilio Sacco, Massimo Sartelli, Alfredo Tonsi, Fabrizio Dal Moro, and Fausto Catena

Subjects
Iatrogenic urinary tract injury, Ureteral injury, Bladder injury, Urinary injury prevention, Urinary injury diagnosis, Urinary injury management, Surgery, RD1-811, Medical emergencies. Critical care. Intensive care. First aid, RC86-88.9
Abstract

Abstract Iatrogenic urinary tract injury (IUTI) is a severe complication of emergency digestive surgery. It can lead to increased postoperative morbidity and mortality and have a long-term impact on the quality of life. The reported incidence of IUTIs varies greatly among the studies, ranging from 0.3 to 1.5%. Given the high volume of emergency digestive surgery performed worldwide, there is a need for well-defined and effective strategies to prevent and manage IUTIs. Currently, there is a lack of consensus regarding the prevention, detection, and management of IUTIs in the emergency setting. The present guidelines, promoted by the World Society of Emergency Surgery (WSES), were developed following a systematic review of the literature and an international expert panel discussion. The primary aim of these WSES guidelines is to provide evidence-based recommendations to support clinicians and surgeons in the prevention, detection, and management of IUTIs during emergency digestive surgery. The following key aspects were considered: (1) effectiveness of preventive interventions for IUTIs during emergency digestive surgery; (2) intra-operative detection of IUTIs and appropriate management strategies; (3) postoperative detection of IUTIs and appropriate management strategies and timing; and (4) effectiveness of antibiotic therapy (including type and duration) in case of IUTIs.

Published
2023
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41. Prognostic Role of Lymphocyte-to-Monocyte Ratio (LMR) in Patients with Intermediate-Stage Hepatocellular Carcinoma (HCC) Undergoing Chemoembolizations (DEM-TACE or cTACE) of the Liver: Exploring the Link between Tumor Microenvironment and Interventional Radiology

Author

Roberto Minici, Massimo Venturini, Giuseppe Guzzardi, Federico Fontana, Andrea Coppola, Filippo Piacentino, Federico Torre, Marco Spinetta, Pietro Maglio, Pasquale Guerriero, Michele Ammendola, MGJR Research Team, Luca Brunese, and Domenico Laganà

Subjects
inflammation-based scores, lymphocyte-to-monocyte ratio (LMR), hepatocellular carcinoma (HCC), transcatheter arterial chemoembolization (TACE), tumor microenvironment, biomarkers, Medicine
Abstract

Inflammation-based scores are biomarkers of the crosstalk between the tumor microenvironment and the immune response. Investigating the intricate relationship between the tumor stromal microenvironment, biomarkers, and the response to transcatheter arterial chemoembolization (TACE) is essential for early identification of TACE refractoriness or failure, providing insights into tumor biology and facilitating personalized therapeutic interventions. This study addresses a dearth of recent literature exploring the prognostic significance of the preoperative LMR in individuals from western countries diagnosed with stage B hepatocellular carcinoma (HCC) undergoing drug eluting microspheres TACE (DEM-TACE) or conventional TACE (cTACE). This international multi-center retrospective analysis included consecutive patients with stage B HCC who underwent TACE from January 2017 to June 2023. The study evaluated the ability of the preoperative LMR to predict complete response (CR), objective response (OR), sustained response duration (SRD) exceeding 6 months, successful downstaging at 6 months, progression-free survival (PFS) at 6 months, and overall survival (OS) at 6 months. The study population included 109 HCC patients and it was divided into low LMR (LMR < 2.24) and high LMR (LMR ≥ 2.24) groups, according to ROC curve analysis to select the optimal LMR cut-off value. High LMR was associated with lower Hepatitis C prevalence, higher absolute lymphocyte count, and a trend toward lower alpha-fetoprotein. The group with high LMRs exhibited superior CR rates (14.9% vs. 0%), overall OR (43.2% vs. 14.3%), and better PFS at 6 months (75.7% vs. 45.7%). The LMR, specifically categorized as

Published
2024
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43. Home Automation and Applied Behavior Analysis: Mand’s Development in the Natural Environment

Author

Morfini, Flavia, Durante, Simona, Ammendola, Angela, Moretto, Enrico, Stanzione, Roberta, Ragozzino, Ottavio, Mosca, Lucia Luciana, Cioffi, Valeria, Maldonato, Nelson Mauro, Muzii, Benedetta, De Lucia, Natascia, Sperandeo, Raffaele, Howlett, Robert J., Series Editor, Jain, Lakhmi C., Series Editor, Esposito, Anna, editor, Faundez-Zanuy, Marcos, editor, Morabito, Francesco Carlo, editor, and Pasero, Eros, editor

Published
2023
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45. Inappropriate therapies in modern implantable cardioverter-defibrillators: A propensity score–matched comparison between single- and dual-chamber discriminators in single-chamber devices THe sINGle lead Study (THINGS Study)

Author

Biffi, Mauro, Statuto, Giovanni, Calvi, Valeria, Iori, Matteo, De Maria, Elia, Bolognesi, Maria Giulia, Allocca, Giuseppe, Notarangelo, Francesca, Carinci, Valeria, Ammendola, Ernesto, Boggian, Giulio, Saporito, Davide, Mancini, Luigi, Potenza, Domenico, Celentano, Eduardo, Giorgi, Davide, and Ziacchi, Matteo

Published
2024
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46. Addendum to: A measurement of the K + → π + μ + μ − decay

Author

The NA62 collaboration, E. Cortina Gil, A. Kleimenova, E. Minucci, S. Padolski, P. Petrov, A. Shaikhiev, R. Volpe, T. Numao, Y. Petrov, B. Velghe, V. W. S. Wong, D. Bryman, J. Fu, T. Husek, J. Jerhot, K. Kampf, M. Zamkovsky, R. Aliberti, G. Khoriauli, J. Kunze, D. Lomidze, L. Peruzzo, M. Vormstein, R. Wanke, P. Dalpiaz, M. Fiorini, I. Neri, A. Norton, F. Petrucci, H. Wahl, A. Cotta Ramusino, A. Gianoli, E. Iacopini, G. Latino, M. Lenti, A. Parenti, A. Bizzeti, F. Bucci, A. Antonelli, G. Georgiev, V. Kozhuharov, G. Lanfranchi, S. Martellotti, M. Moulson, T. Spadaro, G. Tinti, F. Ambrosino, T. Capussela, M. Corvino, D. Di Filippo, R. Fiorenza, P. Massarotti, M. Mirra, M. Napolitano, G. Saracino, G. Anzivino, F. Brizioli, E. Imbergamo, R. Lollini, R. Piandani, C. Santoni, M. Barbanera, P. Cenci, B. Checcucci, P. Lubrano, M. Lupi, M. Pepe, M. Piccini, F. Costantini, L. Di Lella, N. Doble, M. Giorgi, S. Giudici, G. Lamanna, E. Lari, E. Pedreschi, M. Sozzi, C. Cerri, R. Fantechi, L. Pontisso, F. Spinella, I. Mannelli, G. D’Agostini, M. Raggi, A. Biagioni, P. Cretaro, O. Frezza, E. Leonardi, A. Lonardo, M. Turisini, P. Valente, P. Vicini, R. Ammendola, V. Bonaiuto, A. Fucci, A. Salamon, F. Sargeni, R. Arcidiacono, B. Bloch-Devaux, M. Boretto, E. Menichetti, E. Migliore, D. Soldi, C. Biino, A. Filippi, F. Marchetto, J. Engelfried, N. Estrada-Tristan, A. M. Bragadireanu, S. A. Ghinescu, O. E. Hutanu, A. Baeva, D. Baigarashev, D. Emelyanov, T. Enik, V. Falaleev, V. Kekelidze, A. Korotkova, L. Litov, D. Madigozhin, M. Misheva, N. Molokanova, S. Movchan, I. Polenkevich, Yu. Potrebenikov, S. Shkarovskiy, A. Zinchenko, S. Fedotov, E. Gushchin, A. Khotyantsev, Y. Kudenko, V. Kurochka, M. Medvedeva, A. Mefodev, S. Kholodenko, V. Kurshetsov, V. Obraztsov, A. Ostankov, V. Semenov, V. Sugonyaev, O. Yushchenko, L. Bician, T. Blazek, V. Cerny, Z. Kucerova, J. Bernhard, A. Ceccucci, H. Danielsson, N. De Simone, F. Duval, B. Döbrich, L. Federici, E. Gamberini, L. Gatignon, R. Guida, F. Hahn, E. B. Holzer, B. Jenninger, M. Koval, P. Laycock, G. Lehmann Miotto, P. Lichard, A. Mapelli, R. Marchevski, K. Massri, M. Noy, V. Palladino, M. Perrin-Terrin, J. Pinzino, V. Ryjov, S. Schuchmann, S. Venditti, T. Bache, M. B. Brunetti, V. Duk, V. Fascianelli, J. R. Fry, F. Gonnella, E. Goudzovski, J. Henshaw, L. Iacobuzio, C. Lazzeroni, N. Lurkin, F. Newson, C. Parkinson, A. Romano, A. Sergi, A. Sturgess, J. Swallow, A. Tomczak, H. Heath, R. Page, S. Trilov, B. Angelucci, D. Britton, C. Graham, D. Protopopescu, J. Carmignani, J. B. Dainton, R. W. L. Jones, G. Ruggiero, L. Fulton, D. Hutchcroft, E. Maurice, B. Wrona, A. Conovaloff, P. Cooper, D. Coward, and P. Rubin

Subjects
Nuclear and particle physics. Atomic energy. Radioactivity, QC770-798
Published
2023
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47. Biological insights from plasma proteomics of non-small cell lung cancer patients treated with immunotherapy

Author

Jair Bar, Raya Leibowitz, Niels Reinmuth, Astrid Ammendola, Eyal Jacob, Mor Moskovitz, Adva Levy-Barda, Michal Lotem, Rivka Katsenelson, Abed Agbarya, Mahmoud Abu-Amna, Maya Gottfried, Tatiana Harkovsky, Ido Wolf, Ella Tepper, Gil Loewenthal, Ben Yellin, Yehuda Brody, Nili Dahan, Maya Yanko, Coren Lahav, Michal Harel, Shani Raveh Shoval, Yehonatan Elon, Itamar Sela, Adam P. Dicker, and Yuval Shaked

Subjects
PD-1, PD-L1, NSCLC, proteomics, biological process, Immunologic diseases. Allergy, RC581-607
Abstract

IntroductionImmune checkpoint inhibitors have made a paradigm shift in the treatment of non-small cell lung cancer (NSCLC). However, clinical response varies widely and robust predictive biomarkers for patient stratification are lacking. Here, we characterize early on-treatment proteomic changes in blood plasma to gain a better understanding of treatment response and resistance.MethodsPre-treatment (T0) and on-treatment (T1) plasma samples were collected from 225 NSCLC patients receiving PD-1/PD-L1 inhibitor-based regimens. Plasma was profiled using aptamer-based technology to quantify approximately 7000 plasma proteins per sample. Proteins displaying significant fold changes (T1:T0) were analyzed further to identify associations with clinical outcomes using clinical benefit and overall survival as endpoints. Bioinformatic analyses of upregulated proteins were performed to determine potential cell origins and enriched biological processes.ResultsThe levels of 142 proteins were significantly increased in the plasma of NSCLC patients following ICI-based treatments. Soluble PD-1 exhibited the highest increase, with a positive correlation to tumor PD-L1 status, and, in the ICI monotherapy dataset, an association with improved overall survival. Bioinformatic analysis of the ICI monotherapy dataset revealed a set of 30 upregulated proteins that formed a single, highly interconnected network, including CD8A connected to ten other proteins, suggestive of T cell activation during ICI treatment. Notably, the T cell-related network was detected regardless of clinical benefit. Lastly, circulating proteins of alveolar origin were identified as potential biomarkers of limited clinical benefit, possibly due to a link with cellular stress and lung damage.ConclusionsOur study provides insights into the biological processes activated during ICI-based therapy, highlighting the potential of plasma proteomics to identify mechanisms of therapy resistance and biomarkers for outcome.

Published
2024
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48. Improved calorimetric particle identification in NA62 using machine learning techniques

Author

Cortina Gil, E., Kleimenova, A., Minucci, E., Padolski, S., Petrov, P., Shaikhiev, A., Volpe, R., Fedorko, W., Numao, T., Petrov, Y., Velghe, B., Wong, V. W. S., Yu, M., Bryman, D., Fu, J., Hives, Z., Husek, T., Jerhot, J., Kampf, K., Zamkovsky, M., De Martino, B., Perrin-Terrin, M., Akmete, A. T., Aliberti, R., Khoriauli, G., Kunze, J., Lomidze, D., Peruzzo, L., Vormstein, M., Wanke, R., Dalpiaz, P., Fiorini, M., Mazzolari, A., Neri, I., Norton, A., Petrucci, F., Soldani, M., Wahl, H., Bandiera, L., Cotta Ramusino, A., Gianoli, A., Romagnoni, M., Sytov, A., Iacopini, E., Latino, G., Lenti, M., Lo Chiatto, P., Panichi, I., Parenti, A., Bizzeti, A., Bucci, F., Antonelli, A., Georgiev, G., Kozhuharov, V., Lanfranchi, G., Martellotti, S., Moulson, M., Spadaro, T., Tinti, G., Ambrosino, F., Capussela, T., Corvino, M., D’Errico, M., Di Filippo, D., Fiorenza, R., Giordano, R., Massarotti, P., Mirra, M., Napolitano, M., Rosa, I., Saracino, G., Anzivino, G., Brizioli, F., Imbergamo, E., Lollini, R., Piandani, R., Santoni, C., Barbanera, M., Cenci, P., Checcucci, B., Lubrano, P., Lupi, M., Pepe, M., Piccini, M., Costantini, F., Di Lella, L., Doble, N., Giorgi, M., Giudici, S., Lamanna, G., Lari, E., Pedreschi, E., Sozzi, M., Cerri, C., Fantechi, R., Pontisso, L., Spinella, F., Mannelli, I., D’Agostini, G., Raggi, M., Biagioni, A., Cretaro, P., Frezza, O., Leonardi, E., Lonardo, A., Turisini, M., Valente, P., Vicini, P., Ammendola, R., Bonaiuto, V., Fucci, A., Salamon, A., Sargeni, F., Arcidiacono, R., Bloch-Devaux, B., Boretto, M., Menichetti, E., Migliore, E., Soldi, D., Biino, C., Filippi, A., Marchetto, F., Briano Olvera, A., Engelfried, J., Estrada-Tristan, N., Reyes Santos, M. A., Boboc, P., Bragadireanu, A. M., Ghinescu, S. A., Hutanu, O. E., Bician, L., Blazek, T., Cerny, V., Kucerova, Z., Bernhard, J., Ceccucci, A., Ceoletta, M., Danielsson, H., De Simone, N., Duval, F., Döbrich, B., Federici, L., Gamberini, E., Gatignon, L., Guida, R., Hahn, F., Holzer, E. B., Jenninger, B., Koval, M., Laycock, P., Lehmann Miotto, G., Lichard, P., Mapelli, A., Marchevski, R., Massri, K., Noy, M., Palladino, V., Pinzino, J., Ryjov, V., Schuchmann, S., Venditti, S., Bache, T., Brunetti, M. B., Duk, V., Fascianelli, V., Fry, J. R., Gonnella, F., Goudzovski, E., Henshaw, J., Iacobuzio, L., Kenworthy, C., Lazzeroni, C., Lurkin, N., Newson, F., Parkinson, C., Romano, A., Sanders, J., Sergi, A., Sturgess, A., Swallow, J., Tomczak, A., Heath, H., Page, R., Trilov, S., Angelucci, B., Britton, D., Graham, C., Protopopescu, D., Carmignani, J., Dainton, J. B., Jones, R. W. L., Ruggiero, G., Fulton, L., Hutchcroft, D., Maurice, E., Wrona, B., Conovaloff, A., Cooper, P., Coward, D., Rubin, P., Baeva, A., Baigarashev, D., Emelyanov, D., Enik, T., Falaleev, V., Fedotov, S., Gorshanov, K., Gushchin, E., Kekelidze, V., Kereibay, D., Kholodenko, S., Khotyantsev, A., Korotkova, A., Kudenko, Y., Kurochka, V., Kurshetsov, V., Litov, L., Madigozhin, D., Medvedeva, M., Mefodev, A., Misheva, M., Molokanova, N., Movchan, S., Obraztsov, V., Okhotnikov, A., Ostankov, A., Polenkevich, I., Potrebenikov, Yu., Sadovskiy, A., Semenov, V., Shkarovskiy, S., Sugonyaev, V., Yushchenko, O., and Zinchenko, A.

Published
2023
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49. A study of the K+→ π0e+νγ decay

Author

Cortina Gil, E., Kleimenova, A., Minucci, E., Padolski, S., Petrov, P., Shaikhiev, A., Volpe, R., Numao, T., Petrov, Y., Velghe, B., Wong, V. W. S., Bryman, D., Fu, J., Hives, Z., Husek, T., Jerhot, J., Kampf, K., Zamkovsky, M., De Martino, B., Perrin-Terrin, M., Akmete, A. T., Aliberti, R., Khoriauli, G., Kunze, J., Lomidze, D., Peruzzo, L., Vormstein, M., Wanke, R., Dalpiaz, P., Fiorini, M., Mazzolari, A., Neri, I., Norton, A., Petrucci, F., Soldani, M., Wahl, H., Bandiera, L., Cotta Ramusino, A., Gianoli, A., Romagnoni, M., Sytov, A., Iacopini, E., Latino, G., Lenti, M., Lo Chiatto, P., Panichi, I., Parenti, A., Bizzeti, A., Bucci, F., Antonelli, A., Georgiev, G., Kozhuharov, V., Lanfranchi, G., Martellotti, S., Moulson, M., Spadaro, T., Tinti, G., Ambrosino, F., Capussela, T., Corvino, M., D’Errico, M., Di Filippo, D., Fiorenza, R., Giordano, R., Massarotti, P., Mirra, M., Napolitano, M., Rosa, I., Saracino, G., Anzivino, G., Brizioli, F., Imbergamo, E., Lollini, R., Piandani, R., Santoni, C., Barbanera, M., Cenci, P., Checcucci, B., Lubrano, P., Lupi, M., Pepe, M., Piccini, M., Costantini, F., Di Lella, L., Doble, N., Giorgi, M., Giudici, S., Lamanna, G., Lari, E., Pedreschi, E., Sozzi, M., Cerri, C., Fantechi, R., Pontisso, L., Spinella, F., Mannelli, I., D’Agostini, G., Raggi, M., Biagioni, A., Cretaro, P., Frezza, O., Leonardi, E., Lonardo, A., Turisini, M., Valente, P., Vicini, P., Ammendola, R., Bonaiuto, V., Fucci, A., Salamon, A., Sargeni, F., Arcidiacono, R., Bloch-Devaux, B., Boretto, M., Menichetti, E., Migliore, E., Soldi, D., Biino, C., Filippi, A., Marchetto, F., Briano Olvera, A., Engelfried, J., Estrada-Tristan, N., Reyes Santos, M. A., Boboc, P., Bragadireanu, A. M., Ghinescu, S. A., Hutanu, O. E., Bician, L., Blazek, T., Cerny, V., Kucerova, Z., Bernhard, J., Ceccucci, A., Ceoletta, M., Danielsson, H., De Simone, N., Duval, F., Döbrich, B., Federici, L., Gamberini, E., Gatignon, L., Guida, R., Hahn, F., Holzer, E. B., Jenninger, B., Koval, M., Laycock, P., Lehmann Miotto, G., Lichard, P., Mapelli, A., Marchevski, R., Massri, K., Noy, M., Palladino, V., Pinzino, J., Ryjov, V., Schuchmann, S., Venditti, S., Bache, T., Brunetti, M. B., Duk, V., Fascianelli, V., Fry, J. R., Gonnella, F., Goudzovski, E., Henshaw, J., Iacobuzio, L., Kenworthy, C., Lazzeroni, C., Lurkin, N., Newson, F., Parkinson, C., Romano, A., Sanders, J., Sergi, A., Sturgess, A., Swallow, J., Tomczak, A., Heath, H., Page, R., Trilov, S., Angelucci, B., Britton, D., Graham, C., Protopopescu, D., Carmignani, J., Dainton, J. B., Jones, R. W. L., Ruggiero, G., Fulton, L., Hutchcroft, D., Maurice, E., Wrona, B., Conovaloff, A., Cooper, P., Coward, D., Rubin, P., Baeva, A., Baigarashev, D., Emelyanov, D., Enik, T., Falaleev, V., Fedotov, S., Gorshanov, K., Gushchin, E., Kekelidze, V., Kereibay, D., Kholodenko, S., Khotyantsev, A., Korotkova, A., Kudenko, Y., Kurochka, V., Kurshetsov, V., Litov, L., Madigozhin, D., Medvedeva, M., Mefodev, A., Misheva, M., Molokanova, N., Movchan, S., Obraztsov, V., Okhotnikov, A., Ostankov, A., Polenkevich, I., Potrebenikov, Yu., Sadovskiy, A., Semenov, V., Shkarovskiy, S., Sugonyaev, V., Yushchenko, O., and Zinchenko, A.

Published
2023
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50. Search for dark photon decays to μ+μ− at NA62

Author

Cortina Gil, E., Jerhot, J., Kleimenova, A., Lurkin, N., Zamkovsky, M., Numao, T., Velghe, B., Wong, V. W. S., Bryman, D., Hives, Z., Husek, T., Kampf, K., Koval, M., De Martino, B., Perrin-Terrin, M., Akmete, A. T., Aliberti, R., Di Lella, L., Doble, N., Peruzzo, L., Schuchmann, S., Wahl, H., Wanke, R., Dalpiaz, P., Mazzolari, A., Neri, I., Petrucci, F., Soldani, M., Bandiera, L., Cotta Ramusino, A., Gianoli, A., Romagnoni, M., Sytov, A., Lenti, M., Lo Chiatto, P., Marchevski, R., Panichi, I., Ruggiero, G., Bizzeti, A., Bucci, F., Antonelli, A., Kozhuharov, V., Lanfranchi, G., Martellotti, S., Moulson, M., Spadaro, T., Tinti, G., Ambrosino, F., D’Errico, M., Fiorenza, R., Giordano, R., Massarotti, P., Mirra, M., Napolitano, M., Rosa, I., Saracino, G., Anzivino, G., Brizioli, F., Cenci, P., Duk, V., Lollini, R., Lubrano, P., Pepe, M., Piccini, M., Costantini, F., Giorgi, M., Giudici, S., Lamanna, G., Lari, E., Pedreschi, E., Pinzino, J., Sozzi, M., Fantechi, R., Spinella, F., Mannelli, I., Raggi, M., Biagioni, A., Cretaro, P., Frezza, O., Lonardo, A., Turisini, M., Vicini, P., Ammendola, R., Bonaiuto, V., Fucci, A., Salamon, A., Sargeni, F., Arcidiacono, R., Bloch-Devaux, B., Menichetti, E., Migliore, E., Biino, C., Filippi, A., Marchetto, F., Soldi, D., Briano Olvera, A., Engelfried, J., Estrada-Tristan, N., Piandani, R., Reyes Santos, M. A., Boboc, P., Bragadireanu, A. M., Ghinescu, S. A., Hutanu, O. E., Blazek, T., Cerny, V., Kucerova, Z., Volpe, R., Bernhard, J., Bician, L., Boretto, M., Ceccucci, A., Ceoletta, M., Corvino, M., Danielsson, H., Duval, F., Döbrich, B., Federici, L., Gamberini, E., Guida, R., Holzer, E. B., Jenninger, B., Lehmann Miotto, G., Lichard, P., Massri, K., Minucci, E., Noy, M., Ryjov, V., Swallow, J., Fry, J. R., Gonnella, F., Goudzovski, E., Henshaw, J., Kenworthy, C., Lazzeroni, C., Parkinson, C., Romano, A., Sanders, J., Sergi, A., Shaikhiev, A., Tomczak, A., Heath, H., Britton, D., Norton, A., Protopopescu, D., Dainton, J. B., Gatignon, L., Jones, R. W. L., Cooper, P., Coward, D., Rubin, P., Baeva, A., Baigarashev, D., Emelyanov, D., Enik, T., Falaleev, V., Fedotov, S., Gorshanov, K., Gushchin, E., Kekelidze, V., Kereibay, D., Kholodenko, S., Khotyantsev, A., Korotkova, A., Kudenko, Y., Kurochka, V., Kurshetsov, V., Litov, L., Madigozhin, D., Mefodev, A., Misheva, M., Molokanova, N., Obraztsov, V., Okhotnikov, A., Polenkevich, I., Potrebenikov, Yu., Sadovskiy, A., Shkarovskiy, S., Sugonyaev, V., and Yushchenko, O.

Published
2023
Full Text
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