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Your search keyword '"Alesia S. Akulova"' showing total 2 results
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2 results on '"Alesia S. Akulova"'

1. One-Pot Synthesis of Polynuclear Indole Derivatives by Friedel–Crafts Alkylation of γ-Hydroxybutyrolactams

Author

Vladimir T. Abaev, Nicolai A. Aksenov, Dmitrii A. Aksenov, Elena V. Aleksandrova, Alesia S. Akulova, Igor A. Kurenkov, Alexander V. Leontiev, and Alexander V. Aksenov

Subjects
polycyclic indoles, intramolecular Friedel–Crafts reaction, cascade transformations, Organic chemistry, QD241-441
Abstract

The Friedel–Crafts reaction of novel 3,5-diarylsubstituted 5-hydroxy-1,5-dihydro-2H-pyrrol-2-ones was used for low cost, one-pot preparation of polycyclic indole derivatives structurally similar to Ergot alkaloids.

Published
2023
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2. An Effective Synthesis of Previously Unknown 7-Aryl Substituted Paullones

Author

Dmitrii A. Aksenov, Alesia S. Akulova, Elena A. Aleksandrova, Nicolai A. Aksenov, Alexander V. Leontiev, and Alexander V. Aksenov

Subjects
Fisher indolization, paullones synthesis, anticancer drug discovery, Organic chemistry, QD241-441
Abstract

A straightforward three-step procedure affording a wide range of novel 7-aryl substituted paullone derivatives was developed. This scaffold is structurally similar to 2-(1H-indol-3-yl)acetamides—promising antitumor agents—hence, could be useful for the development of a new class of anticancer drugs.

Published
2023
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