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234 results on '"Alemayehu, W"'

1. The Global Trachoma Mapping Project: Methodology of a 34-Country Population-Based Study

Author

Lietman, Thomas, Solomon, AW, Pavluck, AL, Courtright, P, Aboe, A, Adamu, L, Alemayehu, W, Alemu, M, Alexander, NDE, Kello, AB, and Bero, B

Abstract

© Informa Healthcare USA, Inc.Purpose: To complete the baseline trachoma map worldwide by conducting population-based surveys in an estimated 1238 suspected endemic districts of 34 countries. Methods: A series of national and sub-national projects owned, m

Published
2015

3. Biomarker profiles of favorable ventricular remodeling in heart failure patients with reduced ejection fraction: Insights from the echocardiographic substudy of the VICTORIA trial

Author

Tromp, J, primary, Lam, C S P, additional, Alemayehu, W, additional, Defilippi, C, additional, Sliwa, K, additional, Lopatin, Y, additional, Bahit, M C, additional, Roessig, L, additional, O'connor, C M, additional, Shah, P, additional, Westerhout, C M, additional, Voors, A A, additional, and Armstrong, P, additional

Published
2023
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4. Description of Hirschmanniella dicksoni n. sp. (Nematoda: Pratylenchidae) from rhizosphere soil of limpograss from Florida, USA

Author

Habteweld Alemayehu W., Akyazi Faruk, Joseph Soumi, Crow William T., Abebe Eyualem, and Mekete Tesfamariam

Subjects
diagnosis, d2–d3, florida, hirschmanniella, limpograss, its, morphology, morphometric, new species, pcr, phylogeny, Biology (General), QH301-705.5
Abstract

Hirschmanniella dicksoni n. sp. isolated from the rhizosphere soil of limpograss is described and illustrated based on morphology and molecular characters. The new species is characterized by its body length, 1,582 to 1,929 µm, hemispherical lip region with 6 to 7 annules, stylet length 19 to 21 µm, irregularly areolated lateral fields, oval spermatheca filled with rounded sperm, intestine not overlapping the rectum, and tail length 103 to 149 µm, usually with ventral projection with subterminal notch. Males are similar to the females except for their shorter body length and presence of secondary sexual characteristics, with spicules length 19 to 30 µm. The new species is closely related with H. mucronata, H. belli, and H. oryzae. Compared with these three species, the new species has a relatively longer tail and a terminus shape tail with a ventral projection with a subterminal notch. Other morphological and morphometric characteristics that separate these species are as follows: lip region, number of lip annuli, and spicules length. Molecular sequence analysis using the D2–D3 expansion segments of 28S and the ITS rRNA sequences showed that the new species is genetically distinct. D2–D3 sequence of H. dicksoni n. sp. showed 99 and 95% sequence homology with an undescribed species of Hirschmanniella isolated from the Colorado River in Yuma, Arizona, and H. oryzae, respectively. ITS sequence of the new species also showed 88% sequence homology with H. oryzae. The phylogenetic analysis of D2–D3 and ITS region grouped H. dicksoni n. sp., as sister species, with H. oryzae.

Published
2019
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5. The impact of incorporating surgical simulation into trichiasis surgery training on operative aspects of initial live-training surgeries

Author

Pedlingham, N., Tadesse, D., Dykstra, R.S., Alemayehu, W., Johnson, J.E., Sisay, A., Kollmann, K.M., Gower, E.W., Kello, A.B., and Merbs, S.L.

Abstract

BACKGROUND: While surgical simulation is regularly used in surgical training in high-income country settings, it is uncommon in low- and middle-income countries, particularly for surgical training that primarily occurs in rural areas. We designed and evaluated a novel surgical simulator for improving trachomatous trichiasis (TT) surgery training, given that trichiasis is mostly found among the poorest individuals in rural areas. METHODOLOGY/PRINCIPAL FINDINGS: TT surgery programs were invited to incorporate surgical simulation with a new, high fidelity, low-cost simulator into their training. Trainees completed standard TT-surgery training following World Health Organization guidelines. A subset of trainees received three hours of supplemental training with the simulator between classroom and live-surgery training. We recorded the time required to complete each surgery and the number of times the trainer intervened to correct surgical steps. Participants completed questionnaires regarding their perceptions. We also assessed trainer and trainee perceptions of surgical simulation training as part of trichiasis surgery training. 22 surgeons completed standard training and 26 completed standard training plus simulation. We observed 1,394 live-training surgeries. Average time to first live-training surgery completion was nearly 20% shorter the simulation versus the standard group (28.3 vs 34.4 minutes; p = 0.02). Trainers intervened significantly fewer times during initial live-training surgeries in the simulation group (2.7 vs. 4.8; p = 0.005). All trainers indicated the simulator significantly improved training by allowing trainees to practice safely and to identify problem areas before performing live-training surgeries. Trainees reported that simulation practice improved their confidence and skills prior to performing live-training surgeries. CONCLUSIONS: A single high-fidelity surgical simulation session can significantly improve critical aspects of initial TT surgeries.

Published
2023
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6. Causes of blindness and vision impairment in 2020 and trends over 30 years, and prevalence of avoidable blindness in relation to VISION 2020: the Right to Sight: an analysis for the Global Burden of Disease Study

Author

Bourne R. R. A., Steinmetz J. D., Saylan M., Mersha A. M., Weldemariam A. H., Wondmeneh T. G., Sreeramareddy C. T., Pinheiro M., Yaseri M., Yu C., Zastrozhin M. S., Zastrozhina A., Zhang Z. -J., Zimsen S. R. M., Yonemoto N., Tsegaye G. W., Vu G. T., Vongpradith A., Renzaho A. M. N., Sorrie M. B., Shaheen A. A., Shiferaw W. S., Skryabin V. Y., Skryabina A. A., Saya G. K., Rahimi-Movaghar V., Shigematsu M., Sahraian M. A., Naderifar H., Sabour S., Rathi P., Sathian B., Miller T. R., Rezapour A., Rawal L., Pham H. Q., Parekh U., Podder V., Onwujekwe O. E., Pasovic M., Otstavnov N., Negash H., Pawar S., Naimzada M. D., Al Montasir A., Ogbo F. A., Owolabi M. O., Pakshir K., Mohammad Y., Moni M. A., Nunez-Samudio V., Mulaw G. F., Naveed M., Maleki S., Michalek I. M., Misra S., Swamy S. N., Mohammed J. A., Flaxman S., Park E. -C., Briant P. S., Meles G. G., Hayat K., Landires I., Kim G. R., Liu X., LeGrand K. E., Taylor H. R., Kunjathur S. M., Khoja T. A. M., Bicer B. K., Khalilov R., Hashi A., Kayode G. A., Carneiro V. L. A., Kavetskyy T., Kosen S., Kulkarni V., Holla R., Kalhor R., Jayaram S., Islam S. M. S., Gilani S. A., Eskandarieh S., Molla M. D., Itumalla R., Farzadfar F., Congdon N. G., Elhabashy H. R., Elayedath R., Couto R. A. S., Dervenis N., Cromwell E. A., Dahlawi S. M. A., Resnikoff S., Casson R. J., Abdoli A., Choi J. -Y. J., Dos Santos F. L. C., Abrha W. A., Nagaraja S. B., Abualhasan A., Adal T. G., Aregawi B. B., Beheshti M., Abu-Gharbieh E., Afshin A., Ahmadieh H., Alemzadeh S. A., Arrigo A., Atnafu D. D., Ashbaugh C., Ashrafi E., Alemayehu W., Alfaar A. S., Alipour V., Anbesu E. W., Androudi S., Arabloo J., Arditi A., Bagli E., Baig A. A., Barnighausen T. W., Battaglia Parodi M., Bhagavathula A. S., Bhardwaj N., Bhardwaj P., Bhattacharyya K., Bijani A., Bikbov M., Bottone M., Braithwaite T., Bron A. M., Butt Z. A., Cheng C. -Y., Chu D. -T., Cicinelli M. V., Coelho J. M., Dai X., Dana R., Dandona L., Dandona R., Del Monte M. A., Deva J. P., Diaz D., Djalalinia S., Dreer L. E., Ehrlich J. R., Ellwein L. B., Emamian M. H., Fernandes A. G., Fischer F., Friedman D. S., Furtado J. M., Gaidhane S., Gazzard G., Gebremichael B., George R., Ghashghaee A., Golechha M., Hamidi S., Hammond B. R., Hartnett M. E. R., Hartono R. K., Hay S. I., Heidari G., Ho H. C., Househ M., Ibitoye S. E., Ilic I. M., Huang J. J., Ilic M. D., Ingram A. D., Irvani S. S. N., Jha R. P., Kahloun R., Kandel H., Kasa A. S., Kempen J. H., Khairallah M., Khan E. A., Khanna R. C., Khatib M. N., Kim J. E., Kim Y. J., Kisa A., Kisa S., Koyanagi A., Kurmi O. P., Lansingh V. C., Leasher J. L., Leveziel N., Limburg H., Manafi N., Mansouri K., McAlinden C., Mohammadi S. F., Mokdad A. H., Morse A. R., Naderi M., Naidoo K. S., Nangia V., Nguyen H. L. T., Ogundimu K., Olagunju A. T., Panda-Jonas S., Pesudovs K., Peto T., Ur Rahman M. H., Ramulu P. Y., Rawaf D. L., Rawaf S., Reinig N., Robin A. L., Rossetti L., Safi S., Sahebkar A., Samy A. M., Serle J. B., Shaikh M. A., Shen T. T., Shibuya K., Shin J. I., Silva J. C., Silvester A., Singh J. A., Singhal D., Sitorus R. S., Skiadaresi E., Soheili A., Sousa R. A. R. C., Stambolian D., Tadesse E. G., Tahhan N., Tareque Md. I., Topouzis F., Tran B. X., Tsilimbaris M. K., Varma R., Virgili G., Wang N., Wang Y. X., West S. K., Wong T. Y., Jonas J. B., Vos T., Bourne, R. R. A., Steinmetz, J. D., Saylan, M., Mersha, A. M., Weldemariam, A. H., Wondmeneh, T. G., Sreeramareddy, C. T., Pinheiro, M., Yaseri, M., Yu, C., Zastrozhin, M. S., Zastrozhina, A., Zhang, Z. -J., Zimsen, S. R. M., Yonemoto, N., Tsegaye, G. W., Vu, G. T., Vongpradith, A., Renzaho, A. M. N., Sorrie, M. B., Shaheen, A. A., Shiferaw, W. S., Skryabin, V. Y., Skryabina, A. A., Saya, G. K., Rahimi-Movaghar, V., Shigematsu, M., Sahraian, M. A., Naderifar, H., Sabour, S., Rathi, P., Sathian, B., Miller, T. R., Rezapour, A., Rawal, L., Pham, H. Q., Parekh, U., Podder, V., Onwujekwe, O. E., Pasovic, M., Otstavnov, N., Negash, H., Pawar, S., Naimzada, M. D., Al Montasir, A., Ogbo, F. A., Owolabi, M. O., Pakshir, K., Mohammad, Y., Moni, M. A., Nunez-Samudio, V., Mulaw, G. F., Naveed, M., Maleki, S., Michalek, I. M., Misra, S., Swamy, S. N., Mohammed, J. A., Flaxman, S., Park, E. -C., Briant, P. S., Meles, G. G., Hayat, K., Landires, I., Kim, G. R., Liu, X., Legrand, K. E., Taylor, H. R., Kunjathur, S. M., Khoja, T. A. M., Bicer, B. K., Khalilov, R., Hashi, A., Kayode, G. A., Carneiro, V. L. A., Kavetskyy, T., Kosen, S., Kulkarni, V., Holla, R., Kalhor, R., Jayaram, S., Islam, S. M. S., Gilani, S. A., Eskandarieh, S., Molla, M. D., Itumalla, R., Farzadfar, F., Congdon, N. G., Elhabashy, H. R., Elayedath, R., Couto, R. A. S., Dervenis, N., Cromwell, E. A., Dahlawi, S. M. A., Resnikoff, S., Casson, R. J., Abdoli, A., Choi, J. -Y. J., Dos Santos, F. L. C., Abrha, W. A., Nagaraja, S. B., Abualhasan, A., Adal, T. G., Aregawi, B. B., Beheshti, M., Abu-Gharbieh, E., Afshin, A., Ahmadieh, H., Alemzadeh, S. A., Arrigo, A., Atnafu, D. D., Ashbaugh, C., Ashrafi, E., Alemayehu, W., Alfaar, A. S., Alipour, V., Anbesu, E. W., Androudi, S., Arabloo, J., Arditi, A., Bagli, E., Baig, A. A., Barnighausen, T. W., Battaglia Parodi, M., Bhagavathula, A. S., Bhardwaj, N., Bhardwaj, P., Bhattacharyya, K., Bijani, A., Bikbov, M., Bottone, M., Braithwaite, T., Bron, A. M., Butt, Z. A., Cheng, C. -Y., Chu, D. -T., Cicinelli, M. V., Coelho, J. M., Dai, X., Dana, R., Dandona, L., Dandona, R., Del Monte, M. A., Deva, J. P., Diaz, D., Djalalinia, S., Dreer, L. E., Ehrlich, J. R., Ellwein, L. B., Emamian, M. H., Fernandes, A. G., Fischer, F., Friedman, D. S., Furtado, J. M., Gaidhane, S., Gazzard, G., Gebremichael, B., George, R., Ghashghaee, A., Golechha, M., Hamidi, S., Hammond, B. R., Hartnett, M. E. R., Hartono, R. K., Hay, S. I., Heidari, G., Ho, H. C., Househ, M., Ibitoye, S. E., Ilic, I. M., Huang, J. J., Ilic, M. D., Ingram, A. D., Irvani, S. S. N., Jha, R. P., Kahloun, R., Kandel, H., Kasa, A. S., Kempen, J. H., Khairallah, M., Khan, E. A., Khanna, R. C., Khatib, M. N., Kim, J. E., Kim, Y. J., Kisa, A., Kisa, S., Koyanagi, A., Kurmi, O. P., Lansingh, V. C., Leasher, J. L., Leveziel, N., Limburg, H., Manafi, N., Mansouri, K., Mcalinden, C., Mohammadi, S. F., Mokdad, A. H., Morse, A. R., Naderi, M., Naidoo, K. S., Nangia, V., Nguyen, H. L. T., Ogundimu, K., Olagunju, A. T., Panda-Jonas, S., Pesudovs, K., Peto, T., Ur Rahman, M. H., Ramulu, P. Y., Rawaf, D. L., Rawaf, S., Reinig, N., Robin, A. L., Rossetti, L., Safi, S., Sahebkar, A., Samy, A. M., Serle, J. B., Shaikh, M. A., Shen, T. T., Shibuya, K., Shin, J. I., Silva, J. C., Silvester, A., Singh, J. A., Singhal, D., Sitorus, R. S., Skiadaresi, E., Soheili, A., Sousa, R. A. R. C., Stambolian, D., Tadesse, E. G., Tahhan, N., Tareque, Md. I., Topouzis, F., Tran, B. X., Tsilimbaris, M. K., Varma, R., Virgili, G., Wang, N., Wang, Y. X., West, S. K., Wong, T. Y., Jonas, J. B., Vos, T., University of Washington [Seattle], Anglia Ruskin University (ARU), Imperial College London, University of Melbourne, Heidelberg University, Jahrom University of Medical Sciences, Aksum University, Cairo University, University of Sharjah, Wolkite University, Shahid Beheshti University of Medical Sciences [Tehran] (SBUMS), Shahid Beheshti University, The Fred Hollows Foundation, Iran University of Medical Sciences, University of Leipzig Medical Center, University of Thessaly [Volos] (UTH), Visibility Metrics LLC, Adigrat University, San Raffaele Hospital, Tehran University of Medical Sciences (TUMS), Bahir Dar University (BDU), University Hospital of Ioannina, Sultan Zainal Abidin University, Universita Vita Salute San Raffaele = Vita-Salute San Raffaele University [Milan, Italie] (UniSR), Charles University [Prague] (CU), Government Medical College Pali, All India Institute of Medical Sciences, National Institute of Biomedical Genomics, Babol University of Medical Sciences, Ufa Eye Research Institute, ondon School of Hygiene & Tropical Medicine, Service d'Ophtalmologie (CHU de Dijon), Centre Hospitalier Universitaire de Dijon - Hôpital François Mitterrand (CHU Dijon), Centre des Sciences du Goût et de l'Alimentation [Dijon] (CSGA), Université de Bourgogne (UB)-AgroSup Dijon - Institut National Supérieur des Sciences Agronomiques, de l'Alimentation et de l'Environnement-Centre National de la Recherche Scientifique (CNRS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Université Bourgogne Franche-Comté [COMUE] (UBFC), Employee State Insurance Post Graduate Institute of Medical Sciences and Research, University of Waterloo [Waterloo], Federal Polytechnic School of Lausanne, University of Minho, University of Adelaide, Singapore Eye Research Institute [Singapore] (SERI), Seoul National University Hospital, Hanoi National University of Education (HNUE), IRCCS San Raffaele Scientific Institute [Milan, Italie], University of Porto, Queen's University [Belfast] (QUB), University of Dammam - Imam Abdulrahman Bin Faisal University, Harvard University, University of Michigan [Ann Arbor], University of Michigan System, University of Gondar, Royal Liverpool University Hospital, Universiti Tunku Abdul Rahman (UTAR), National Autonomous University of Mexico (UNAM), Ministry of Health and Medical Education [Iran] (MOHME), Mahatma Gandhi University of Medical Sciences and Technology, Cairo University - Faculty of Medicine, National Institutes of Health [Bethesda] (NIH), Shahroud University of Medical Sciences, Federal University of Sao Paulo (Unifesp), University of Applied Sciences Ravensburg-Weingarten, University of São Paulo (USP), Datta Meghe Institute of Medical Sciences, University College of London [London] (UCL), Haramaya University, Sankara Nethralaya Medical Research Foundation, The University of Lahore, Indian Institute of Public Health Gandhinagar, Hamdan Bin Mohammed Smart University, University of Georgia, University of Utah, Institution of Public Health Sciences, Jigjiga Universit, University of Veterinary and Animal Sciences, Independent Consultant, The Chinese University of Hong Kong [Hong Kong], Manipal academy of Higher Education, Hamad Bin Khalifa University (HBKU), Yale University [New Haven], University of Ibadan, University of Belgrade [Belgrade], Faculty of Science of the University of Kragujevac, University of Kragujevac, Deakin University, Burwood, Australia, Deakin University [Burwood], University of Hail, Mysore Medical College, Banaras Hindu University [Varanasi] (BHU), Ophtalmologistes Associe Monastir, Qazvin University of Medical Sciences, The University of Sydney, John Paul II Catholic University of Lublin (KUL), Institute of Human Virology [Nigeria] (IHVN), Myungsung Medical College, Centre Hospitalier Universitaire Fattouma Bourguiba, Partenaires INRAE, Baku State University, Health Services Academy, L V Prasad Eye Institute, Health Ministers Council Gulf Cooperative Council Stat, Medical College of Wisconsin [Milwaukee] (MCW), Xiamen University Malaysia, Yonsei University, Oslo Metropolitan University (OsloMet), School of Optometry and Vision Science, UNSW Sydney, Sydney, NSW, Australia, Brien Holden Vision Institute, Fondation Théa, The Fred Hollows Foundation, Bill & Melinda Gates Foundation, Lions Clubs International Foundation, Sightsavers International, and University of Heidelberg., and GBD 2019 Blindness and Vision Impairment Collaborators* on behalf of the Vision Loss Expert Group of the Global Burden of Disease Study.

Subjects
Pediatrics, medicine.medical_specialty, Refractive error, Visual acuity, genetic structures, Eye disease, 030231 tropical medicine, Population, Glaucoma, 03 medical and health sciences, 0302 clinical medicine, medicine, Global health, 030212 general & internal medicine, [SDV.MHEP.OS]Life Sciences [q-bio]/Human health and pathology/Sensory Organs, education, education.field_of_study, business.industry, Articles, General Medicine, Diabetic retinopathy, Macular degeneration, medicine.disease, eye diseases, 3. Good health, medicine.symptom, business
Abstract

Background: Many causes of vision impairment can be prevented or treated. With an ageing global population, the demands for eye health services are increasing. We estimated the prevalence and relative contribution of avoidable causes of blindness and vision impairment globally from 1990 to 2020. We aimed to compare the results with the World Health Assembly Global Action Plan (WHA GAP) target of a 25% global reduction from 2010 to 2019 in avoidable vision impairment, defined as cataract and undercorrected refractive error. Methods: We did a systematic review and meta-analysis of population-based surveys of eye disease from January, 1980, to October, 2018. We fitted hierarchical models to estimate prevalence (with 95% uncertainty intervals [UIs]) of moderate and severe vision impairment (MSVI; presenting visual acuity from

Published
2021

8. Geographic variation in heart failure with reduced ejection fraction: insights from the VICTORIA trial

Author

Tsutsui, H, primary, Lam, C S P, additional, Zhang, J, additional, Godoy-Palomino, A, additional, Tziakas, D, additional, Cohen-Solal, A, additional, Freitas, C, additional, Patel, M J, additional, Ezekowitz, J A, additional, Hernandez, A F, additional, Pieske, B, additional, O'Connor, C M, additional, Westerhout, C M, additional, Alemayehu, W, additional, and Armstrong, P W, additional

Published
2022
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10. Retention in HIV Care and Predictors of Attrition from Care among HIV-Infected Adults Receiving Combination Anti-Retroviral Therapy in Addis Ababa.

Author

Legese A Mekuria, Jan M Prins, Alemayehu W Yalew, Mirjam A G Sprangers, and Pythia T Nieuwkerk

Subjects
Medicine, Science
Abstract

Patient retention in chronic HIV care is a major challenge following the rapid expansion of combination antiretroviral therapy (cART) in Ethiopia.To describe the proportion of patients who are retained in HIV care and characterize predictors of attrition among HIV-infected adults receiving cART in Addis Ababa.A retrospective analysis was conducted among 836 treatment naïve patients, who started cART between May 2009 and April 2012. Patients were randomly selected from ten health-care facilities, and their current status in HIV care was determined based on routinely available data in the medical records. Patients lost to follow-up (LTFU) were traced by telephone. Kaplan-Meier technique was used to estimate survival probabilities of retention and Cox proportional hazards regression was performed to identify the predictors of attrition.Based on individual patient data from the medical records, nearly 80% (95%CI: 76.7, 82.1) of the patients were retained in care in the first 3 and half years of antiretroviral therapy. After successfully tracing more than half of the LTFU patients, the updated one year retention in care estimate became 86% (95% CI: 83.41%, 88.17%). In the multivariate Cox regression analyses, severe immune deficiency at enrolment in care/or at cART initiation and 'bed-ridden' or 'ambulatory' functional status at the start of cART predicted attrition.Retention in HIV care in Addis Ababa is comparable with or even better than previous findings from other resource-limited as well as EU/USA settings. However, measures to detect and enroll patients in HIV care as early as possible are still necessary.

Published
2015
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12. 도로상에서 차량의 통제를 위한 상하이동식 자동 볼라드의 전기구동 시스템 개발연구

Author

Young-Jin Kim, Alemayehu w. Huluka, Choi Sung-Hwan, and Kim， Chul Ho

Subjects
Load testing, Reliability (semiconductor), Computer science, Design tool, Process (computing), Electric power, Time limit, computer.software_genre, computer, Automotive engineering, Physical security, Power (physics)
Abstract

A retractable bollard system has been used for the traffic control and protection of important facilities such as electric power plants, airports and government buildings etc. The power source of the driving unit of the conventional protective bollard system is on hydraulic or pneumatic system which has several disadvantages compared to an electric driven unit. In this research, an electric driven unit for an automatic retractable bollard is designed and developed to replace the conventional hydraulic and pneumatic driven type. For the reliability test of the developed electric driven unit, a field test has been successfully done. A case study was conducted to develop a defensive retractive bollard which the target performance is 9sec. and 7sec. on its raising and descending operation speed respectively with 750mm in stroke. The required time limit was fully satisfied as the time measured from the experiment were 7.5sec and 5.5sec for each operation. The developed unit also passed 364,000 cycles of operation without any serious malfunctions at the load test proving its reliability. The design theory and process of an electric driven unit of the automatic retractable bollard presented in this article is believed to be very useful contribution and design tool in advancing the physical security industry.

Published
2019

13. Causes of blindness and vision impairment in 2020 and trends over 30 years, and prevalence of avoidable blindness in relation to VISION 2020: the Right to Sight: an analysis for the Global Burden of Disease Study

Author

Steinmetz, JD, Bourne, RRA, Briant, PS, Flaxman, S, Taylor, HR, Jonas, JB, Abdoli, A, Abrha, WA, Abualhasan, A, Abu-Gharbieh, E, Adal, TG, Afshin, A, Ahmadieh, H, Alemayehu, W, Alemzadeh, SA, Alfaar, AS, Alipour, V, Androudi, S, Arabloo, J, Arditi, A, Aregawi, BB, Arrigo, A, Ashbaugh, C, Ashrafi, E, Atnafu, DD, Bagli, E, Baig, AA, Barnighausen, TW, Parodi, MB, Beheshti, M, Bhagavathula, AS, Bhardwaj, N, Bhardwaj, P, Bhattacharyya, K, Bijani, A, Bikbov, M, Bottone, M, Braithwaite, T, Bron, AM, Nagaraja, SB, Butt, ZA, dos Santos, FLC, Carneiro, VLA, Casson, RJ, Cheng, C-Y, Choi, J-YJ, Chu, D-T, Cicinelli, MV, Coelho, JM, Congdon, NG, Couto, RAS, Cromwell, EA, Dahlawi, SMA, Dai, X, Dana, R, Dandona, L, Dandona, R, Del Monte, MA, Molla, MD, Dervenis, N, Desta, AA, Deva, JP, Diaz, D, Djalalinia, S, Ehrlich, JR, Elayedath, R, Elhabashy, HR, Ellwein, LB, Emamian, MH, Eskandarieh, S, Farzadfar, F, Fernandes, AG, Fischer, F, Friedman, DS, Furtado, JM, Gaidhane, S, Gazzard, G, Gebremichael, B, George, R, Ghashghaee, A, Gilani, SA, Golechha, M, Hamidi, S, Hammond, BR, Hartnett, MER, Hartono, RK, Hashi, A, Hay, S, Hayat, K, Heidari, G, Ho, HC, Holla, R, Househ, M, Huang, JJ, Ibitoye, SE, Ilic, IM, Ilic, MD, Ingram, AD, Irvani, SSN, Islam, SMS, Itumalla, R, Jayaram, S, Jha, RP, Kahloun, R, Kalhor, R, Kandel, H, Kasa, AS, Kavetskyy, T, Kayode, GA, Kempen, JH, Khairallah, M, Khalilov, R, Khan, EA, Khanna, RC, Khatib, MN, Khoja, TAM, Kim, GR, Kim, JE, Kim, YJ, Kisa, A, Kisa, S, Kosen, S, Koyanagi, A, Bicer, BK, Kulkarni, V, Kurmi, OP, Landires, I, Lansingh, VC, Leasher, JL, LeGrand, KE, Leveziel, N, Limburg, H, Liu, X, Kunjathur, SM, Maleki, S, Manafi, N, Mansouri, K, McAlinden, C, Meles, GG, Mersha, AM, Michalek, IM, Miller, TR, Misra, S, Mohammad, Y, Mohammadi, SF, Mohammed, JA, Mokdad, AH, Moni, MA, Al Montasir, A, Morse, AR, Mulaw, GF, Naderi, M, Naderifar, H, Naidoo, KS, Naimzada, MD, Nangia, V, Swamy, SN, Naveed, M, Negash, H, Huong, LTN, Nunez-Samudio, V, Ogbo, FA, Ogundimu, K, Olagunju, AT, Onwujekwe, OE, Otstavnov, N, Owolabi, MO, Pakshir, K, Panda-Jonas, S, Parekh, U, Park, E-C, Pasovic, M, Pawar, S, Pesudovs, K, Peto, T, Pham, HQ, Pinheiro, M, Podder, V, Rahimi-Movaghar, V, Rahman, MHU, Ramulu, PY, Rathi, P, Rawaf, DL, Rawaf, S, Rawal, L, Reinig, N, Renzaho, AMN, Rezapour, A, Robin, AL, Rossetti, L, Sabour, S, Safi, S, Sahebkar, A, Sahraian, MA, Samy, AM, Sathian, B, Saya, GK, Saylan, M, Shaheen, AA, Shaikh, MA, Shen, TT, Shibuya, K, Shiferaw, WS, Shigematsu, M, Shin, JI, Silva, JC, Silvester, A, Singh, JA, Singhal, D, Sitorus, RS, Skiadaresi, E, Skryabin, VY, Skryabina, AA, Soheili, A, Sorrie, MB, Sousa, RARC, Sreeramareddy, CT, Stambolian, D, Tadesse, EG, Tahhan, N, Tareque, MI, Topouzis, F, Bach, XT, Tsegaye, GW, Tsilimbaris, MK, Varma, R, Virgili, G, Vongpradith, A, Vu, GT, Wang, YX, Wang, N, Weldemariam, AH, West, SK, Wondmeneh, TG, Wong, TY, Yaseri, M, Yonemoto, N, Yu, C, Zastrozhin, MS, Zastrozhina, A, Zhang, Z-J, Zimsen, SRM, Resnikoff, S, Vos, T, Steinmetz, JD, Bourne, RRA, Briant, PS, Flaxman, S, Taylor, HR, Jonas, JB, Abdoli, A, Abrha, WA, Abualhasan, A, Abu-Gharbieh, E, Adal, TG, Afshin, A, Ahmadieh, H, Alemayehu, W, Alemzadeh, SA, Alfaar, AS, Alipour, V, Androudi, S, Arabloo, J, Arditi, A, Aregawi, BB, Arrigo, A, Ashbaugh, C, Ashrafi, E, Atnafu, DD, Bagli, E, Baig, AA, Barnighausen, TW, Parodi, MB, Beheshti, M, Bhagavathula, AS, Bhardwaj, N, Bhardwaj, P, Bhattacharyya, K, Bijani, A, Bikbov, M, Bottone, M, Braithwaite, T, Bron, AM, Nagaraja, SB, Butt, ZA, dos Santos, FLC, Carneiro, VLA, Casson, RJ, Cheng, C-Y, Choi, J-YJ, Chu, D-T, Cicinelli, MV, Coelho, JM, Congdon, NG, Couto, RAS, Cromwell, EA, Dahlawi, SMA, Dai, X, Dana, R, Dandona, L, Dandona, R, Del Monte, MA, Molla, MD, Dervenis, N, Desta, AA, Deva, JP, Diaz, D, Djalalinia, S, Ehrlich, JR, Elayedath, R, Elhabashy, HR, Ellwein, LB, Emamian, MH, Eskandarieh, S, Farzadfar, F, Fernandes, AG, Fischer, F, Friedman, DS, Furtado, JM, Gaidhane, S, Gazzard, G, Gebremichael, B, George, R, Ghashghaee, A, Gilani, SA, Golechha, M, Hamidi, S, Hammond, BR, Hartnett, MER, Hartono, RK, Hashi, A, Hay, S, Hayat, K, Heidari, G, Ho, HC, Holla, R, Househ, M, Huang, JJ, Ibitoye, SE, Ilic, IM, Ilic, MD, Ingram, AD, Irvani, SSN, Islam, SMS, Itumalla, R, Jayaram, S, Jha, RP, Kahloun, R, Kalhor, R, Kandel, H, Kasa, AS, Kavetskyy, T, Kayode, GA, Kempen, JH, Khairallah, M, Khalilov, R, Khan, EA, Khanna, RC, Khatib, MN, Khoja, TAM, Kim, GR, Kim, JE, Kim, YJ, Kisa, A, Kisa, S, Kosen, S, Koyanagi, A, Bicer, BK, Kulkarni, V, Kurmi, OP, Landires, I, Lansingh, VC, Leasher, JL, LeGrand, KE, Leveziel, N, Limburg, H, Liu, X, Kunjathur, SM, Maleki, S, Manafi, N, Mansouri, K, McAlinden, C, Meles, GG, Mersha, AM, Michalek, IM, Miller, TR, Misra, S, Mohammad, Y, Mohammadi, SF, Mohammed, JA, Mokdad, AH, Moni, MA, Al Montasir, A, Morse, AR, Mulaw, GF, Naderi, M, Naderifar, H, Naidoo, KS, Naimzada, MD, Nangia, V, Swamy, SN, Naveed, M, Negash, H, Huong, LTN, Nunez-Samudio, V, Ogbo, FA, Ogundimu, K, Olagunju, AT, Onwujekwe, OE, Otstavnov, N, Owolabi, MO, Pakshir, K, Panda-Jonas, S, Parekh, U, Park, E-C, Pasovic, M, Pawar, S, Pesudovs, K, Peto, T, Pham, HQ, Pinheiro, M, Podder, V, Rahimi-Movaghar, V, Rahman, MHU, Ramulu, PY, Rathi, P, Rawaf, DL, Rawaf, S, Rawal, L, Reinig, N, Renzaho, AMN, Rezapour, A, Robin, AL, Rossetti, L, Sabour, S, Safi, S, Sahebkar, A, Sahraian, MA, Samy, AM, Sathian, B, Saya, GK, Saylan, M, Shaheen, AA, Shaikh, MA, Shen, TT, Shibuya, K, Shiferaw, WS, Shigematsu, M, Shin, JI, Silva, JC, Silvester, A, Singh, JA, Singhal, D, Sitorus, RS, Skiadaresi, E, Skryabin, VY, Skryabina, AA, Soheili, A, Sorrie, MB, Sousa, RARC, Sreeramareddy, CT, Stambolian, D, Tadesse, EG, Tahhan, N, Tareque, MI, Topouzis, F, Bach, XT, Tsegaye, GW, Tsilimbaris, MK, Varma, R, Virgili, G, Vongpradith, A, Vu, GT, Wang, YX, Wang, N, Weldemariam, AH, West, SK, Wondmeneh, TG, Wong, TY, Yaseri, M, Yonemoto, N, Yu, C, Zastrozhin, MS, Zastrozhina, A, Zhang, Z-J, Zimsen, SRM, Resnikoff, S, and Vos, T

Abstract

BACKGROUND: Many causes of vision impairment can be prevented or treated. With an ageing global population, the demands for eye health services are increasing. We estimated the prevalence and relative contribution of avoidable causes of blindness and vision impairment globally from 1990 to 2020. We aimed to compare the results with the World Health Assembly Global Action Plan (WHA GAP) target of a 25% global reduction from 2010 to 2019 in avoidable vision impairment, defined as cataract and undercorrected refractive error. METHODS: We did a systematic review and meta-analysis of population-based surveys of eye disease from January, 1980, to October, 2018. We fitted hierarchical models to estimate prevalence (with 95% uncertainty intervals [UIs]) of moderate and severe vision impairment (MSVI; presenting visual acuity from <6/18 to 3/60) and blindness (<3/60 or less than 10° visual field around central fixation) by cause, age, region, and year. Because of data sparsity at younger ages, our analysis focused on adults aged 50 years and older. FINDINGS: Global crude prevalence of avoidable vision impairment and blindness in adults aged 50 years and older did not change between 2010 and 2019 (percentage change -0·2% [95% UI -1·5 to 1·0]; 2019 prevalence 9·58 cases per 1000 people [95% IU 8·51 to 10·8], 2010 prevalence 96·0 cases per 1000 people [86·0 to 107·0]). Age-standardised prevalence of avoidable blindness decreased by -15·4% [-16·8 to -14·3], while avoidable MSVI showed no change (0·5% [-0·8 to 1·6]). However, the number of cases increased for both avoidable blindness (10·8% [8·9 to 12·4]) and MSVI (31·5% [30·0 to 33·1]). The leading global causes of blindness in those aged 50 years and older in 2020 were cataract (15·2 million cases [9% IU 12·7-18·0]), followed by glaucoma (3·6 million cases [2·8-4·4]), undercorrected refractive error (2·3 million cases [1·8-2·8]), age-related macular degeneration (1·8 million cases [1·3-2·4]), and diabetic retinopathy (0·86 mill

Published
2021

14. Trends in prevalence of blindness and distance and near vision impairment over 30 years: an analysis for the Global Burden of Disease Study

Author

Bourne, RRA, Steinmetz, JD, Flaxman, S, Briant, PS, Taylor, HR, Resnikoff, S, Casson, RJ, Abdoli, A, Abu-Gharbieh, E, Afshin, A, Ahmadieh, H, Akalu, Y, Alamneh, AA, Alemayehu, W, Alfaar, AS, Alipour, V, Anbesu, EW, Androudi, S, Arabloo, J, Arditi, A, Asaad, M, Bagli, E, Baig, AA, Barnighausen, TW, Parodi, MB, Bhagavathula, AS, Bhardwaj, N, Bhardwaj, P, Bhattacharyya, K, Bijani, A, Bikbov, M, Bottone, M, Braithwaite, T, Bron, AM, Butt, ZA, Cheng, C-Y, Chu, D-T, Cicinelli, MV, Coelho, JM, Dagnew, B, Dai, X, Dana, R, Dandona, L, Dandona, R, Del Monte, MA, Deva, JP, Diaz, D, Djalalinia, S, Dreer, LE, Ehrlich, JR, Ellwein, LB, Emamian, MH, Fernandes, AG, Fischer, F, Friedman, DS, Furtado, JM, Gaidhane, AM, Gaidhane, S, Gazzard, G, Gebremichael, B, George, R, Ghashghaee, A, Golechha, M, Hamidi, S, Hammond, BR, Hartnett, MER, Hartono, RK, Hay, S, Heidari, G, Ho, HC, Chi, LH, Househ, M, Ibitoye, SE, Ilic, IM, Ilic, MD, Ingram, AD, Irvani, SSN, Jha, RP, Kahloun, R, Kandel, H, Kasa, AS, Kempen, JH, Keramati, M, Khairallah, M, Khan, EA, Khanna, RC, Khatib, MN, Kim, JE, Kim, YJ, Kisa, A, Kisa, S, Koyanagi, A, Kurmi, OP, Lansingh, VC, Leasher, JL, Leveziel, N, Limburg, H, Majdan, M, Manafi, N, Mansouri, K, McAlinden, C, Mohammadi, SF, Mohammadian-Hafshejani, A, Mohammadpourhodki, R, Mokdad, AH, Moosavi, D, Morse, AR, Naderi, M, Naidoo, KS, Nangia, V, Cuong, TN, Huong, LTN, Ogundimu, K, Olagunju, AT, Ostroff, SM, Panda-Jonas, S, Pesudovs, K, Peto, T, Syed, ZQ, Rahman, MHU, Ramulu, PY, Rawaf, DL, Rawaf, S, Reinig, N, Robin, AL, Rossetti, L, Safi, S, Sahebkar, A, Samy, AM, Saxena, D, Serle, JB, Shaikh, MA, Shen, TT, Shibuya, K, Shin, JI, Silva, JC, Silvester, A, Singh, JA, Singhal, D, Sitorus, RS, Skiadaresi, E, Skirbekk, V, Soheili, A, Sousa, RARC, Spurlock, EE, Stambolian, D, Taddele, BW, Tadesse, EG, Tahhan, N, Tareque, MI, Topouzis, F, Bach, XT, Travillian, RS, Tsilimbaris, MK, Varma, R, Virgili, G, Wang, N, Wang, YX, West, SK, Wong, TY, Zaidi, Z, Zewdie, KA, Jonas, JB, Vos, T, Bourne, RRA, Steinmetz, JD, Flaxman, S, Briant, PS, Taylor, HR, Resnikoff, S, Casson, RJ, Abdoli, A, Abu-Gharbieh, E, Afshin, A, Ahmadieh, H, Akalu, Y, Alamneh, AA, Alemayehu, W, Alfaar, AS, Alipour, V, Anbesu, EW, Androudi, S, Arabloo, J, Arditi, A, Asaad, M, Bagli, E, Baig, AA, Barnighausen, TW, Parodi, MB, Bhagavathula, AS, Bhardwaj, N, Bhardwaj, P, Bhattacharyya, K, Bijani, A, Bikbov, M, Bottone, M, Braithwaite, T, Bron, AM, Butt, ZA, Cheng, C-Y, Chu, D-T, Cicinelli, MV, Coelho, JM, Dagnew, B, Dai, X, Dana, R, Dandona, L, Dandona, R, Del Monte, MA, Deva, JP, Diaz, D, Djalalinia, S, Dreer, LE, Ehrlich, JR, Ellwein, LB, Emamian, MH, Fernandes, AG, Fischer, F, Friedman, DS, Furtado, JM, Gaidhane, AM, Gaidhane, S, Gazzard, G, Gebremichael, B, George, R, Ghashghaee, A, Golechha, M, Hamidi, S, Hammond, BR, Hartnett, MER, Hartono, RK, Hay, S, Heidari, G, Ho, HC, Chi, LH, Househ, M, Ibitoye, SE, Ilic, IM, Ilic, MD, Ingram, AD, Irvani, SSN, Jha, RP, Kahloun, R, Kandel, H, Kasa, AS, Kempen, JH, Keramati, M, Khairallah, M, Khan, EA, Khanna, RC, Khatib, MN, Kim, JE, Kim, YJ, Kisa, A, Kisa, S, Koyanagi, A, Kurmi, OP, Lansingh, VC, Leasher, JL, Leveziel, N, Limburg, H, Majdan, M, Manafi, N, Mansouri, K, McAlinden, C, Mohammadi, SF, Mohammadian-Hafshejani, A, Mohammadpourhodki, R, Mokdad, AH, Moosavi, D, Morse, AR, Naderi, M, Naidoo, KS, Nangia, V, Cuong, TN, Huong, LTN, Ogundimu, K, Olagunju, AT, Ostroff, SM, Panda-Jonas, S, Pesudovs, K, Peto, T, Syed, ZQ, Rahman, MHU, Ramulu, PY, Rawaf, DL, Rawaf, S, Reinig, N, Robin, AL, Rossetti, L, Safi, S, Sahebkar, A, Samy, AM, Saxena, D, Serle, JB, Shaikh, MA, Shen, TT, Shibuya, K, Shin, JI, Silva, JC, Silvester, A, Singh, JA, Singhal, D, Sitorus, RS, Skiadaresi, E, Skirbekk, V, Soheili, A, Sousa, RARC, Spurlock, EE, Stambolian, D, Taddele, BW, Tadesse, EG, Tahhan, N, Tareque, MI, Topouzis, F, Bach, XT, Travillian, RS, Tsilimbaris, MK, Varma, R, Virgili, G, Wang, N, Wang, YX, West, SK, Wong, TY, Zaidi, Z, Zewdie, KA, Jonas, JB, and Vos, T

Abstract

BACKGROUND: To contribute to the WHO initiative, VISION 2020: The Right to Sight, an assessment of global vision impairment in 2020 and temporal change is needed. We aimed to extensively update estimates of global vision loss burden, presenting estimates for 2020, temporal change over three decades between 1990-2020, and forecasts for 2050. METHODS: We did a systematic review and meta-analysis of population-based surveys of eye disease from January, 1980, to October, 2018. Only studies with samples representative of the population and with clearly defined visual acuity testing protocols were included. We fitted hierarchical models to estimate 2020 prevalence (with 95% uncertainty intervals [UIs]) of mild vision impairment (presenting visual acuity ≥6/18 and <6/12), moderate and severe vision impairment (<6/18 to 3/60), and blindness (<3/60 or less than 10° visual field around central fixation); and vision impairment from uncorrected presbyopia (presenting near vision

Published
2021

19. Low vision and blindness in adults in Gurage Zone, central Ethiopia. (World View)

Author

Melese, M., Alemayehu, W., Bayu, S., Girma, T., Hailesellasie, T., Khandekar, R., Worku, A., and Courtright, P.

Subjects
Blindness -- Research, Low vision -- Research, Ophthalmology -- Research, Health, Research
Abstract

Aim: To determine the magnitude and causes of low vision and blindness in the Gurage zone, central Ethiopia. Methods: A cross sectional study using a multistage cluster sampling technique was [...]

Published
2003

20. Pesky trachoma suspect finally caught

Author

Miller, K, Pakpour, N, Yi, E, Melese, M, Alemayehu, W, Bird, M, Schmidt, G, Cevallos, V, Olinger, L, Chidambaram, J, Gaynor, B, Whitcher, J, and Lietman, T

Published
2004

24. Intimate partner violence against women in western Ethiopia: prevalence, patterns, and associated factors

Author

Abeya Sileshi G, Afework Mesganaw F, and Yalew Alemayehu W

Subjects
Intimate partner violence, Women, Prevalence, Patterns, Factors, Public aspects of medicine, RA1-1270
Abstract

Abstract Background Intimate partner violence against women is the psychological, physical, and sexual abuse directed to spouses. Globally it is the most pervasive yet underestimated human rights violation. This study was aimed at investigating the prevalence, patterns and associated factors of intimate partner violence against women in Western Ethiopia. Methods A cross-sectional, population based household survey was conducted from January to April, 2011 using standard WHO multi-country study questionnaire. A sample of 1540 ever married/cohabited women aged 15-49 years was randomly selected from urban and rural settings of East Wollega Zone, Western Ethiopia. Data were principally analyzed using logistic regression. Results Lifetime and past 12 months prevalence of intimate partner violence against women showed 76.5% (95% CI: 74.4-78.6%) and 72.5% (95% CI: 70.3-74.7%), respectively. The overlap of psychological, physical, and sexual violence was 56.9%. The patterns of the three forms of violence are similar across the time periods. Rural residents (AOR 0.58, 95% CI 0.34-0.98), literates (AOR 0.65, 95% CI 0.48-0.88), female headed households (AOR 0.46, 95% CI 0.27-0.76) were at decreased likelihood to have lifetime intimate partner violence. Yet, older women were nearly four times (AOR 3.36, 95% CI 1.27-8.89) more likely to report the incident. On the other hand, abduction (AOR 3.71, 95% CI 1.01-13.63), polygamy (AOR 3.79, 95% CI 1.64-0.73), spousal alcoholic consumption (AOR 1.98, 95% CI 1.21-3.22), spousal hostility (AOR 3.96, 95% CI 2.52-6.20), and previous witnesses of parental violence (AOR 2.00, 95% CI 1.54-2.56) were factors associated with an increased likelihood of lifetime intimate partner violence against women. Conclusion In their lifetime, three out of four women experienced at least one incident of intimate partner violence. This needs an urgent attention at all levels of societal hierarchy including policymakers, stakeholders and professionals to alleviate the situation.

Published
2011
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25. Progress Towards Elimination of Trachoma as a Public Health Problem in Eritrea: Results of a Systematic Review and Nine Population-based Prevalence Surveys Conducted in 2014

Author

Tesfazion, A, Zecarias, A, Zewengiel, S, Willis, R, Mebrahtu, G, Capa, E, Mpyet, C, Al-Khatib, T, Courtright, P, Solomon, AW, Aboe, A, Adamu, L, Alemayehu, W, Alemu, M, Alexander, NDE, Bakhtiari, A, Bero, B, Boisson, S, Bovill, S, Brooker, SJ, Bush, S, Chu, BK, Dejene, M, Emerson, PM, Flueckiger, RM, Foster, A, Gadisa, S, Gass, K, Gebre, T, Habtamu, Z, Haddad, D, Harvey, E, Haslam, D, Kalua, K, Kello, AB, King, JD, Le Mesurier, R, Lewallen, S, Lietman, TM, MacArthur, C, Macleod, C, Mariotti, SP, Massae, PA, Massey, A, Mathieu, E, McCullagh, S, Mekasha, A, Millar, T, Munoz, B, Ngondi, J, Ogden, S, Pavluck, A, Pearce, J, Resnikoff, S, Sarah, V, Sarr, B, Sisay, A, Smith, JL, Thomson, J, West, SK, Tesfazion, A, Zecarias, A, Zewengiel, S, Willis, R, Mebrahtu, G, Capa, E, Mpyet, C, Al-Khatib, T, Courtright, P, Solomon, AW, Aboe, A, Adamu, L, Alemayehu, W, Alemu, M, Alexander, NDE, Bakhtiari, A, Bero, B, Boisson, S, Bovill, S, Brooker, SJ, Bush, S, Chu, BK, Dejene, M, Emerson, PM, Flueckiger, RM, Foster, A, Gadisa, S, Gass, K, Gebre, T, Habtamu, Z, Haddad, D, Harvey, E, Haslam, D, Kalua, K, Kello, AB, King, JD, Le Mesurier, R, Lewallen, S, Lietman, TM, MacArthur, C, Macleod, C, Mariotti, SP, Massae, PA, Massey, A, Mathieu, E, McCullagh, S, Mekasha, A, Millar, T, Munoz, B, Ngondi, J, Ogden, S, Pavluck, A, Pearce, J, Resnikoff, S, Sarah, V, Sarr, B, Sisay, A, Smith, JL, Thomson, J, and West, SK

Abstract

PURPOSE: To assess Eritrea's progress towards elimination of trachoma as a public health problem, we reviewed and compiled current knowledge on the distribution and burden of trachoma in Eritrea, then undertook further population-based surveys where indicated, with support from the Global Trachoma Mapping Project (GTMP). METHODS: For the systematic review, undertaken in March 2014, we searched (1) PubMed, using the terms ((blind* or trachoma or trichiasis) AND Eritrea); (2) the online database of rapid assessments of avoidable blindness; (3) our own grey literature collections; and (4) the Global Atlas of Trachoma database. In June and July 2014, we conducted nine population-based prevalence surveys, for each of which 30 villages were systematically selected with probability proportional to population size; in each village, 30 households were systematically selected. All consenting residents of selected households aged ≥1 year were examined by GTMP-certified graders for signs of trachoma. Data on household-level access to water and sanitation were also collected. RESULTS: One previous rapid assessment of avoidable blindness, three peer-reviewed publications, and two grey literature reports detailing sets of trachoma prevalence surveys conducted in 2006 and 2011, respectively, were located. Post-intervention impact surveys were needed in seven evaluation units (EUs, framed at sub-Zoba-level: population range 40,000-120,000) of Debub and Northern Red Sea, while baseline surveys were needed in two EUs of Anseba. Four of the seven impact survey EUs and both baseline survey EUs returned trachomatous inflammation-follicular prevalences in 1-9-year-olds of ≥5%; six of the seven impact survey EUs and one of the two baseline survey EUs returned trichiasis prevalences in ≥15-year-olds of ≥0.2%. The prevalence of access to water and sanitation varied widely between EUs. CONCLUSION: Interventions are still required in Eritrea to eliminate trachoma as a public health problem. Da

Published
2018

26. Prevalence of trachoma in four marakez of Elmenia and Bani Suef Governorates, Egypt

Author

Amer, K, Mueller, A, Abdelhafiz, HM, Al-Khatib, T, Bakhtiari, A, Boisson, S, El Arab, GE, Gad, H, Gordon, BA, Madian, A, Mahanna, AT, Mokhtar, S, Safa, OH, Samy, M, Shalaby, M, Taha, ZA, Willis, R, Yacoub, A, Mamdouh, AR, Younis, AK, Zoheir, MBE, Courtright, P, Solomon, AW, Aboe, A, Adamu, L, Alemayehu, W, Alemu, M, Alexander, NDE, Bero, B, Bovill, S, Brooker, SJ, Bush, S, Chu, BK, Dejene, M, Emerson, PM, Flueckiger, RM, Foster, A, Gadisa, S, Gass, K, Gebre, T, Habtamu, Z, Haddad, D, Harvey, E, Haslam, D, Kalua, K, Kello, AB, King, JD, Le Mesurier, R, Lewallen, S, Lietman, TM, MacArthur, C, Macleod, C, Mariotti, SP, Massey, A, Mathieu, E, McCullagh, S, Mekasha, A, Millar, T, Mpyet, C, Munoz, B, Ngondi, J, Ogden, S, Pavluck, A, Pearce, J, Resnikoff, S, Sarah, V, Sarr, B, Sisay, A, Smith, JL, Thomson, J, West, SK, Amer, K, Mueller, A, Abdelhafiz, HM, Al-Khatib, T, Bakhtiari, A, Boisson, S, El Arab, GE, Gad, H, Gordon, BA, Madian, A, Mahanna, AT, Mokhtar, S, Safa, OH, Samy, M, Shalaby, M, Taha, ZA, Willis, R, Yacoub, A, Mamdouh, AR, Younis, AK, Zoheir, MBE, Courtright, P, Solomon, AW, Aboe, A, Adamu, L, Alemayehu, W, Alemu, M, Alexander, NDE, Bero, B, Bovill, S, Brooker, SJ, Bush, S, Chu, BK, Dejene, M, Emerson, PM, Flueckiger, RM, Foster, A, Gadisa, S, Gass, K, Gebre, T, Habtamu, Z, Haddad, D, Harvey, E, Haslam, D, Kalua, K, Kello, AB, King, JD, Le Mesurier, R, Lewallen, S, Lietman, TM, MacArthur, C, Macleod, C, Mariotti, SP, Massey, A, Mathieu, E, McCullagh, S, Mekasha, A, Millar, T, Mpyet, C, Munoz, B, Ngondi, J, Ogden, S, Pavluck, A, Pearce, J, Resnikoff, S, Sarah, V, Sarr, B, Sisay, A, Smith, JL, Thomson, J, and West, SK

Abstract

PURPOSE: In 2015, to determine where interventions are needed to eliminate trachoma as a public health problem from Egypt, we initiated population-based prevalence surveys using the Global Trachoma Mapping Project platform in four suspected-endemic marakez (districts; singular: markaz) of the governorates of Elmenia and Bani Suef. METHODS: In each markaz, 30 households were selected in each of 25 villages. Certified graders examined a total of 3682 children aged 1-9 years in 2993 households, noting the presence or absence of trachomatous inflammation-follicular (TF) and trachomatous inflammation-intense (TI) in each eye. A total of 5582 adults aged ≥15 years living in the same households were examined for trachomatous trichiasis (TT). Household-level access to water and sanitation was recorded. RESULTS: Three of four marakez had age-adjusted TF prevalence estimates in 1-9-year olds of >10%; the other markaz had a TF prevalence estimate of 5-9.9%. Estimates of the age- and gender-adjusted prevalence of unmanaged TT in adults ranged from 0.7% to 2.3%. Household-level access to water and sanitation was high. (We did not, however, measure use of water or sanitation facilities.) Conclusions: Each of the four marakez surveyed has trachoma as a public health problem, with a need for implementation of the SAFE (surgery, antibiotics, facial cleanliness, environmental improvement) strategy. Further mapping is also required to determine the need for interventions in other areas of Egypt.

Published
2018

27. Epidemiology of trachoma and its implications for implementing the 'SAFE' strategy in Somali Region, Ethiopia: results of 14 population-based prevalence surveys

Author

Duale, AB, Ayele, NN, Macleod, CK, Kello, AB, Gezachew, ZE, Binegdie, A, Dejene, M, Alemayehu, W, Flueckiger, RM, Massae, PA, Willis, R, Negash, BK, Solomon, AW, Aboe, A, Adamu, L, Alemu, M, Alexander, NDE, Bero, B, Brooker, SJ, Bush, S, Chu, BK, Courtright, P, Emerson, PM, Foster, A, Gadisa, S, Gass, K, Gebre, T, Habtamu, Z, Kalua, DH, King, JD, Le Mesurier, R, Lewallen, S, Lietman, TM, MacArthur, C, Macleod, C, Mariotti, SP, Massey, A, Mathieu, E, McCullagh, S, Mekasha, A, Millar, T, Mpyet, C, Munoz, B, Ngondi, J, Ogden, S, Pavluck, A, Pearce, J, Resnikoff, S, Sarah, V, Sarr, B, Sisay, A, Smith, JL, Thomson, J, West, SK, Duale, AB, Ayele, NN, Macleod, CK, Kello, AB, Gezachew, ZE, Binegdie, A, Dejene, M, Alemayehu, W, Flueckiger, RM, Massae, PA, Willis, R, Negash, BK, Solomon, AW, Aboe, A, Adamu, L, Alemu, M, Alexander, NDE, Bero, B, Brooker, SJ, Bush, S, Chu, BK, Courtright, P, Emerson, PM, Foster, A, Gadisa, S, Gass, K, Gebre, T, Habtamu, Z, Kalua, DH, King, JD, Le Mesurier, R, Lewallen, S, Lietman, TM, MacArthur, C, Macleod, C, Mariotti, SP, Massey, A, Mathieu, E, McCullagh, S, Mekasha, A, Millar, T, Mpyet, C, Munoz, B, Ngondi, J, Ogden, S, Pavluck, A, Pearce, J, Resnikoff, S, Sarah, V, Sarr, B, Sisay, A, Smith, JL, Thomson, J, and West, SK

Abstract

PURPOSE: Ethiopia is highly trachoma endemic. Baseline mapping was needed in Ethiopia's Somali Region to guide elimination efforts. METHODS: Cross-sectional community-based surveys were conducted in 34 suspected trachoma-endemic woredas, grouped as 14 evaluation units (EUs), using a standardised mapping methodology developed for the Global Trachoma Mapping Project. RESULTS: In total, 53,467 individuals were enumerated. A total of 48,058 (89.9%) were present at the time of survey teams' visits and consented to examination. The prevalence of trachomatous inflammation-follicular (TF) among children aged 1-9 years ranged from 4.1% in the EU covering Danot, Boh, and Geladin woredas in Doolo Subzone to 38.1% in the EU covering Kebribeyah and Hareshen woredas in Fafan Subzone (East). The trichiasis prevalence among adults aged over 15 years varied from 0.1% in the EU covering Afder, Bare, and Dolobay woredas in Afder Subzone (West) to 1.2% in the EU covering Awbere in Fafan Subzone (West). CONCLUSION: Mass drug administration (MDA) with azithromycin is needed in 13 EUs (population 2,845,818). Two EUs (population 667,599) had TF prevalences in 1-9-year-olds of ≥30% and will require at least 5 years of MDA; 5 EUs (population 1,1193,032) had TF prevalences of 10-29.9% and need at least three years of MDA; 6 EUs (population 985,187) had TF prevalences of 5-9.9% and need at least one round of azithromycin distribution before re-survey. In all 13 of these EUs, implementation of facial cleanliness and environmental improvement measures is also needed. Surveys are still needed in the remaining 34 unmapped woredas of Somali Region.

Published
2018

28. Isolation and characterization of efficient Phosphate Solubilizing Bacillus (PSB) from different agro-ecological zones of Tigray soil, Ethiopia

Author

Kibrom, F.G., Alemayehu, W., Prakasam, V.R., and Kiros, W.

Abstract

Applications of biofertilizer have great practical importance for increasing fertility of the soil and reducing environmental pollution. Screening and characterizing phosphate solubilizing Bacillus (PSB) strains from different agroecologies of Tigray soil and in vitro assessment for the adaptability under different abiotic stress would help in selecting the most efficient strain for use as biofertilizer. A total of 64 soil samples were collected from different agro-ecological zones of Tigray and checked for the presence, capability and efficiency of PSB. Out of 64 soil samples 21 of them were phosphate solubilizing. These phosphate solubilizing strains again incubate at 37˚C for 48h on pikovskaya medium to see efficacy of phosphate solubilization. Highest efficiency was recorded in MUB28, MUB47and MUB64 isolates and also tolerant to acidity and alkaline up to pH4 and pH8, respectively. And difference was recorded in saline tolerance among the strains: MUB47 is the most saline tolerance strain which tolerate saline up to 513mM of sodium chloride (NaCl) but MUB28 and MUB64 have tolerated saline up to 340mM of NaCl. The identification of efficient PSB candidate strains with salt & pH tolerant features in the soil sample could have an implication on the end-users to obtain the desired beneficial effect such as maintaining soil healthy, provision of adequate phosphorus from soil to the plant and improving crop yield of Tigray Agriculture. Based on the morphological, microscopic, biochemical and physiological characterization, it may be inferred that the diversity among these efficient PSB strains is low.Keywords: Biofertilizer, Phosphate solubilizing Bacillus, Efficiency, Diversity, Agroecology, Adaptability, Ethiopia.

Published
2017

29. Effect of the Air Duct System of a Simplified Vehicle Model on Aerodynamic Performance.

Author

Huluka, Alemayehu W. and Chul-Ho Kim

Subjects
AIR ducts, VEHICLE models, DRAG (Aerodynamics), DRAG reduction, ENERGY consumption, MICRO air vehicles
Abstract

In this numerical study, ducted and flipped Ahmed model is used to study aerodynamic characteristics of ducted models and how ducting would contribute to the energy consumption reduction effort from aerodynamic resistance. Three-dimensional, incompressible, and steady governing equations were solved by commercial software PHOENICS (version 2018) with extended k-ε turbulent model proposed by Chen-Kim (1987). The study can be considered as a steppingstone to bring a new approach to design aerodynamically efficient vehicle by ducting target vehicles. To investigate the feasibility of the ducting for aerodynamic energy efficiency improvement, fundamental study has been conducted numerically on a simple body before applying to appropriate vehicle model. It is observed from the study that ducting a cross-sectional area of 9.6% of a model would reduce over 19% of the pressure drag at a speed of 100 km/h, to the contrary the increase in skin friction drag is noted although its significance to the total drag is very less compared to pressure drag. Therefore, study of air duct and its effect on aerodynamic performance is expected to contribute to improvement of electric vehicle aerodynamic performance. [ABSTRACT FROM AUTHOR]

Published
2020
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32. Sub-optimal adherence to combination anti-retroviral therapy and its associated factors according to self-report, clinician-recorded and pharmacy-refill assessment methods among HIV-infected adults in Addis Ababa

Author

Mekuria, L.A. (Legese A.), Prins, J.M. (Jan), Yalew, A.W. (Alemayehu W.), Sprangers, M.A.G. (Mirjam), Nieuwkerk, P.T. (Pythia), Mekuria, L.A. (Legese A.), Prins, J.M. (Jan), Yalew, A.W. (Alemayehu W.), Sprangers, M.A.G. (Mirjam), and Nieuwkerk, P.T. (Pythia)

Abstract

Adherence to combination antiretroviral therapy (cART) is generally high in most resource-limited settings. However, sub-optimal adherence occurs in a sizable proportion of patients, and is independently predictive of detectable viremia. We investigated sub-optimal adherence according to self-report, clinician-recorded, and pharmacy-refill assessment methods, and their associated factors among HIV-infected adults receiving cART in Addis Ababa, Ethiopia. Eight-hundred seventy patients who initiated cART between May 2009 and April 2012 were randomly selected, and 664 patients who were alive, had remained in clinical care and were receiving cART for at least six-months were included. Sub-optimal adherence was defined as patients’ response of less than “all-of the time” to the self-report adherence question, or any clinician-recorded poor adherence during the six most recent clinic visits, or a pharmacy-refill of <95% medication possession ratio (MPR). Logistic regression models were fitted to identify factors associated with sub-optimal adherence. The average adherence level to cART, expressed as MPR, was nearly 97%. However, sub-optimal adherence occurred in 12%, 4%, and 27% of patients according to self-report, clinician-recorded, and pharmacy-refill measures, respectively. More satisfaction with social support was significantly associated with less sub-optimal adherence according to self-report and clinician-record. Younger age, lower educational level, and lower CD4 cell count at cART initiation were significantly associated with sub-optimal refill-based adherence. Findings from our large multi-center study suggest that sub-optimal adherence was present in up to a quarter of the patients, despite a high degree of average adherence to cART. Interventions aimed at preventing sub-optimal adherence should focus on improving social support, on younger patients, on patients with lower educational level, and on those who started cART at a lower CD4 cell count.

Published
2017
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34. NUTRIENT CONTENT AND FERMENTATION CHARACTERISTICS OF ENSILED ITALIAN RYEGRASS AND WINTER CEREAL MIXTURES FOR DAIRY COWS.

Author

Alemayehu, W., Tঋthi, R., Orosz, Szilvia, Fébel, Hedvig, Kacsala, L., Båzår, G., and Tamas, T.

Subjects
RYEGRASSES, FERMENTATION, LACTIC acid, WINTER grain, FORAGE harvesting machinery
Abstract

Copyright of Krmiva is the property of Croatian Society of Agronomists and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2019

35. Study and Development of Vehicle Collision Detection System

Author

Alemayehu W. Huluka and Hirpa G. Lemu

Subjects
Vehicle accident, Engineering, Acceleration, Action (philosophy), business.industry, Control (management), Process (computing), Collision detection, business, Collision, Electronic systems, Automotive engineering, Simulation
Abstract

In order to reduce the alarmingly increasing vehicle accident worldwide, developing collision detection system has been an endeavor of engineers within the last 3–4 decades. Based on the vehicles’ speed and acceleration, detecting the safe distance is one of the approaches reported in research results and claimed patents. As speed and acceleration of both the involved vehicles is changing with time, developing effective algorithms that can capture and process sufficient dynamic information and then warn for or take appropriate action is demanded. One possible approach that can contribute to the effort of minimizing vehicle collision accidents is to use embedded electronic systems to control the speed of the vehicle(s). Accordingly, the study and research work reported in this article focuses on developing a model of rear-end anti-collision system that can detect the distance between two vehicles moving on the same lane in the same direction and alert the driver whenever danger is eminent within certain tolerance range.Copyright © 2014 by ASME

Published
2014

38. Hypofractionated Versus Conventionally Fractionated Radiation Therapy for Prostate Cancer: Five-Year Oncologic Outcomes of the Dutch Randomized Phase 3 HYPRO Trial

Author

Incrocci, L., primary, Wortel, R.C., additional, Aluwini, S., additional, Schimmel, E., additional, Krol, A.D.G., additional, Van Der Toorn, P.P., additional, de Jager, H., additional, Dirkx, M., additional, Alemayehu, W. Ghidey, additional, Heijmen, B., additional, and Pos, F.J., additional

Published
2016
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39. Retention in HIV care and predictors of attrition from care among HIV-infected adults receiving combination anti-retroviral therapy in Addis Ababa

Author

Mekuria, L.A. (Legese A.), Prins, J.M. (Jan), Yalew, A.W. (Alemayehu W.), Sprangers, M.A.G. (Mirjam), Nieuwkerk, P.T. (Pythia), Mekuria, L.A. (Legese A.), Prins, J.M. (Jan), Yalew, A.W. (Alemayehu W.), Sprangers, M.A.G. (Mirjam), and Nieuwkerk, P.T. (Pythia)

Abstract

Background: Patient retention in chronic HIV care is a major challenge following the rapid expansion of combination antiretroviral therapy (cART) in Ethiopia. Objective: To describe the proportion of patients who are retained in HIV care and characterize predictors of attrition among HIV-infected adults receiving cART in Addis Ababa. Method: A retrospective analysis was conducted among 836 treatment naïve patients, who started cART between May 2009 and April 2012. Patients were randomly selected from ten healthcare facilities, and their current status in HIV care was determined based on routinely available data in the medical records. Patients lost to follow-up (LTFU) were traced by telephone. Kaplan-Meier technique was used to estimate survival probabilities of retention and Cox proportional hazards regression was performed to identify the predictors of attrition. Results: Based on individual patient data from the medical records, nearly 80% (95%CI: 76.7, 82.1) of the patients were retained in care in the first 3 and half years of antiretroviral therapy. After successfully tracing more than half of the LTFU patients, the updated one year retention in care estimate became 86% (95% CI: 83.41%, 88.17%). In the multivariate Cox regression analyses, severe immune deficiency at enrolment in care/or at cART initiation and 'bed-ridden' or 'ambulatory' functional status at the start of cART predicted attrition. Conclusion: Retention in HIV care in Addis Ababa is comparable with or even better than previous findings from other resource-limited as well as EU/USA settings. However, measures to detect and enroll patients in HIV care as early as possible are still necessary.

Published
2015
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40. The Global Trachoma Mapping Project: Methodology of a 34-Country Population-Based Study

Author

Solomon, AW, Pavluck, AL, Courtright, P, Aboe, A, Adamu, L, Alemayehu, W, Alemu, M, Alexander, NDE, Kello, AB, Bero, B, Brooker, SJ, Chu, BK, Dejene, M, Emerson, PM, Flueckiger, RM, Gadisa, S, Gass, K, Gebre, T, Habtamu, Z, Harvey, E, Haslam, D, King, JD, Le Mesurier, R, Lewallen, S, Lietman, TM, MacArthur, C, Mariotti, SP, Massey, A, Mathieu, E, Mekasha, A, Millar, T, Mpyet, C, Munoz, BE, Ngondi, J, Ogden, S, Pearce, J, Sarah, V, Sisay, A, Smith, JL, Taylor, HR, Thomson, J, West, SK, Willis, R, Bush, S, Haddad, D, Foster, A, Solomon, AW, Pavluck, AL, Courtright, P, Aboe, A, Adamu, L, Alemayehu, W, Alemu, M, Alexander, NDE, Kello, AB, Bero, B, Brooker, SJ, Chu, BK, Dejene, M, Emerson, PM, Flueckiger, RM, Gadisa, S, Gass, K, Gebre, T, Habtamu, Z, Harvey, E, Haslam, D, King, JD, Le Mesurier, R, Lewallen, S, Lietman, TM, MacArthur, C, Mariotti, SP, Massey, A, Mathieu, E, Mekasha, A, Millar, T, Mpyet, C, Munoz, BE, Ngondi, J, Ogden, S, Pearce, J, Sarah, V, Sisay, A, Smith, JL, Taylor, HR, Thomson, J, West, SK, Willis, R, Bush, S, Haddad, D, and Foster, A

Abstract

PURPOSE: To complete the baseline trachoma map worldwide by conducting population-based surveys in an estimated 1238 suspected endemic districts of 34 countries. METHODS: A series of national and sub-national projects owned, managed and staffed by ministries of health, conduct house-to-house cluster random sample surveys in evaluation units, which generally correspond to "health district" size: populations of 100,000-250,000 people. In each evaluation unit, we invite all residents aged 1 year and older from h households in each of c clusters to be examined for clinical signs of trachoma, where h is the number of households that can be seen by 1 team in 1 day, and the product h × c is calculated to facilitate recruitment of 1019 children aged 1-9 years. In addition to individual-level demographic and clinical data, household-level water, sanitation and hygiene data are entered into the purpose-built LINKS application on Android smartphones, transmitted to the Cloud, and cleaned, analyzed and ministry-of-health-approved via a secure web-based portal. The main outcome measures are the evaluation unit-level prevalence of follicular trachoma in children aged 1-9 years, prevalence of trachomatous trichiasis in adults aged 15 + years, percentage of households using safe methods for disposal of human feces, and percentage of households with proximate access to water for personal hygiene purposes. RESULTS: In the first year of fieldwork, 347 field teams commenced work in 21 projects in 7 countries. CONCLUSION: With an approach that is innovative in design and scale, we aim to complete baseline mapping of trachoma throughout the world in 2015.

Published
2015

41. Description of Hirschmanniella dicksonin. sp. (Nematoda: Pratylenchidae) from rhizosphere soil of limpograss from Florida, USA

Author

Habteweld, Alemayehu W., Akyazi, Faruk, Joseph, Soumi, Crow, William T., Abebe, Eyualem, and Mekete, Tesfamariam

Abstract

Hirschmanniella dicksonin. sp. isolated from the rhizosphere soil of limpograss is described and illustrated based on morphology and molecular characters. The new species is characterized by its body length, 1,582 to 1,929 µm, hemispherical lip region with 6 to 7 annules, stylet length 19 to 21 µm, irregularly areolated lateral fields, oval spermatheca filled with rounded sperm, intestine not overlapping the rectum, and tail length 103 to 149 µm, usually with ventral projection with subterminal notch. Males are similar to the females except for their shorter body length and presence of secondary sexual characteristics, with spicules length 19 to 30 µm. The new species is closely related with H. mucronata, H. belli, and H. oryzae.Compared with these three species, the new species has a relatively longer tail and a terminus shape tail with a ventral projection with a subterminal notch. Other morphological and morphometric characteristics that separate these species are as follows: lip region, number of lip annuli, and spicules length. Molecular sequence analysis using the D2–D3 expansion segments of 28S and the ITS rRNA sequences showed that the new species is genetically distinct. D2–D3 sequence of H. dicksonin. sp. showed 99 and 95% sequence homology with an undescribed species of Hirschmanniellaisolated from the Colorado River in Yuma, Arizona, and H. oryzae,respectively. ITS sequence of the new species also showed 88% sequence homology with H. oryzae.The phylogenetic analysis of D2–D3 and ITS region grouped H. dicksonin. sp., as sister species, with H. oryzae.

Published
2019
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42. Rates and risk factors for unfavorable outcomes 6 weeks after trichiasis surgery

Author

Alemayehu, W., Kello, A.B., Imeru, A., Munoz, B., Merbs, S.L., Gower, E.W., and West, S.K.

Abstract

PURPOSE. Several studies of trichiasis recurrence suggest an association between surgical factors and long-term recurrence, yet data on short-term risk factors are limited. This study was conducted to evaluate risk factors for early trichiasis recurrence and other unfavorable short-term outcomes. METHODS. Trichiasis patients presenting for surgery were evaluated for presence of active trachoma and signs of cicatricial outcomes of trachoma, including number of trichiatic lashes, epilation, and entropion. Surgical factors recorded included incision length, surgery duration, and the surgeon performing the operation. Participants were followed up for 6 weeks after surgery and evaluated for eyelid closure defect and trichiasis recurrence; in addition, in two thirds of the patients, eyelid contour abnormality and granuloma formation were evaluated. RESULTS. First-time trichiasis surgery was performed on 2615 eyelids. Of these, 2601 eyelids without surgical failure were followed up 6 weeks after surgery. Of the eyelids treated, 2.3% had recurrent trichiasis and 1.3% had an eyelid closure defect. Data on eyelid contour abnormalities and granuloma formation were recorded for 1881 eyes, with rates of 1.2% and 10.5%, respectively. Associated risk factors differed by outcome. Surgeon was predictive of eyelid closure defect and granuloma formation. Eyelids with short incisions were nearly four times more likely to have recurrent trichiasis (95% confidence interval, 1.7-9.3). Baseline trichiasis severity was predictive of eyelid contour abnormalities and recurrent trichiasis. Epilation was associated with granuloma formation, but was protective against eyelid closure defect. CONCLUSIONS. Surgical factors are important predictors of unfavorable outcomes in the weeks immediately after surgery. Although the overall rate of serious uncorrectable unfavorable outcomes was very low, the high rate of granuloma formation, which can be treated by removal, highlights the need for follow-up of patients after trichiasis surgery.

Published
2011
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43. Impact of trichiasis surgery on physical functioning in Ethiopian patients: Star trial

Author

West, S.K., Munoz, B.E., Wang, J., Cassard, S.D., Gower, E.W., Alemayehu, W., and Wolle, M.A.

Abstract

Purpose To evaluate the physical functioning of Ethiopian trichiasis surgery patients before and 6 months after surgery. Design Nested cohort study. Methods This study was nested within the Surgery for Trichiasis, Antibiotics to Prevent Recurrence (STAR) clinical trial conducted in Ethiopia. Demographic information, ocular examinations, and physical functioning assessments were collected before and 6 months after surgery. A single score for patients' physical functioning was constructed using Rasch analysis. A multivariate linear regression model was used to determine if change in physical functioning was associated with change in visual acuity. Results Of the 438 participants, 411 (93.8%) had both baseline and follow-up questionnaires. Physical functioning scores at baseline ranged from -6.32 (great difficulty) to +6.01 (no difficulty). The percentage of participants reporting no difficulty in physical functioning increased by 32.6%; the proportion of participants in the mild/no visual impairment category increased by 8.6%. A multivariate linear regression model showed that for every line of vision gained, physical functioning improves significantly (0.09 units; 95% CI: 0.020.16). Conclusions Surgery to correct trichiasis appears to improve patients' physical functioning as measured at 6 months. More effort in promoting trichiasis surgery is essential, not only to prevent corneal blindness, but also to enable improved functioning in daily life.

Published
2011
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48. Sub-optimal adherence to combination anti-retroviral therapy and its associated factors according to self-report, clinician-recorded and pharmacy-refill assessment methods among HIV-infected adults in Addis Ababa.

Author

Mekuria, Legese A., Prins, Jan M., Yalew, Alemayehu W., Sprangers, Mirjam A. G., and Nieuwkerk, Pythia T.

Subjects
HIV infections & psychology, ANTIRETROVIRAL agents, AGE distribution, COMBINATION drug therapy, DRUGS, HIV infections, INTERVIEWING, MEDICAL cooperation, PATIENT compliance, RESEARCH, RESEARCH funding, SELF-evaluation, LOGISTIC regression analysis, VIRAL load, EDUCATIONAL attainment, HIGHLY active antiretroviral therapy, DATA analysis software, CD4 lymphocyte count
Abstract

Adherence to combination antiretroviral therapy (cART) is generally high in most resource-limited settings. However, sub-optimal adherence occurs in a sizable proportion of patients, and is independently predictive of detectable viremia. We investigated sub-optimal adherence according to self-report, clinician-recorded, and pharmacy-refill assessment methods, and their associated factors among HIV-infected adults receiving cART in Addis Ababa, Ethiopia. Eight-hundred seventy patients who initiated cART between May 2009 and April 2012 were randomly selected, and 664 patients who were alive, had remained in clinical care and were receiving cART for at least six-months were included. Sub-optimal adherence was defined as patients’ response of less than “all-of the time” to the self-report adherence question, or any clinician-recorded poor adherence during the six most recent clinic visits, or a pharmacy-refill of <95% medication possession ratio (MPR). Logistic regression models were fitted to identify factors associated with sub-optimal adherence. The average adherence level to cART, expressed as MPR, was nearly 97%. However, sub-optimal adherence occurred in 12%, 4%, and 27% of patients according to self-report, clinician-recorded, and pharmacy-refill measures, respectively. More satisfaction with social support was significantly associated with less sub-optimal adherence according to self-report and clinician-record. Younger age, lower educational level, and lower CD4 cell count at cART initiation were significantly associated with sub-optimal refill-based adherence. Findings from our large multi-center study suggest that sub-optimal adherence was present in up to a quarter of the patients, despite a high degree of average adherence to cART. Interventions aimed at preventing sub-optimal adherence should focus on improving social support, on younger patients, on patients with lower educational level, and on those who started cART at a lower CD4 cell count. [ABSTRACT FROM PUBLISHER]

Published
2017
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