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Your search keyword '"Al‐Obaidi, Magda J."' showing total 7 results
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7 results on '"Al‐Obaidi, Magda J."'

1. Preclinical toxicology and safety pharmacology of the first-in-class GADD45β/MKK7 inhibitor and clinical candidate, DTP3

Author

Tornatore, Laura, Capece, Daria, D'Andrea, Daniel, Begalli, Federica, Verzella, Daniela, Bennett, Jason, Acton, Gary, Campbell, Elizabeth A., Kelly, James, Tarbit, Michael, Adams, Nigel, Bannoo, Selina, Leonardi, Antonio, Sandomenico, Annamaria, Raimondo, Domenico, Ruvo, Menotti, Chambery, Angela, Oblak, Metod, Al-Obaidi, Magda J., Kaczmarski, Richard S., Gabriel, Ian, Oakervee, Heather E., Kaiser, Martin F., Wechalekar, Ashutosh, Benjamin, Reuben, Apperley, Jane F., Auner, Holger W., and Franzoso, Guido

Published
2019
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2. Reliability of a Novel Hematological Malignancy Specific Patient-Reported Outcome Measure: HM-PRO

Author

Goswami, Pushpendra, primary, Oliva, Esther N., additional, Ionova, Tatyana, additional, Else, Roger, additional, Kell, Jonathan, additional, Fielding, Adele K., additional, Jennings, Daniel M., additional, Karakantza, Marina, additional, Al-Ismail, Saad, additional, Collins, Graham P., additional, McConnell, Stewart, additional, Langton, Catherine, additional, Al-Obaidi, Magda J., additional, Oblak, Metod, additional, and Salek, Sam, additional

Published
2020
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3. Hematological Malignancy Specific Patient-Reported Outcome Measure (HM-PRO): Construct Validity Study

Author

Goswami, Pushpendra, primary, Oliva, Esther N., additional, Ionova, Tatyana, additional, Else, Roger, additional, Kell, Jonathan, additional, Fielding, Adele K., additional, Jennings, Daniel M., additional, Karakantza, Marina, additional, Al-Ismail, Saad, additional, Collins, Graham P., additional, McConnell, Stewart, additional, Langton, Catherine, additional, Al-Obaidi, Magda J., additional, Oblak, Metod, additional, and Salek, Sam, additional

Published
2020
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4. Clinical proof of concept for a safe and effective NF ‐κB‐targeting strategy in multiple myeloma

Author

Tornatore, Laura, primary, Capece, Daria, additional, D'Andrea, Daniel, additional, Begalli, Federica, additional, Verzella, Daniela, additional, Bennett, Jason, additional, Acton, Gary, additional, Campbell, Elizabeth A., additional, Kelly, James, additional, Tarbit, Michael, additional, Adams, Nigel, additional, Bannoo, Selina, additional, Leonardi, Antonio, additional, Sandomenico, Annamaria, additional, Raimondo, Domenico, additional, Ruvo, Menotti, additional, Chambery, Angela, additional, Oblak, Metod, additional, Al‐Obaidi, Magda J., additional, Kaczmarski, Richard S., additional, Gabriel, Ian, additional, Oakervee, Heather E., additional, Kaiser, Martin F., additional, Wechalekar, Ashutosh, additional, Benjamin, Reuben, additional, Apperley, Jane F., additional, Auner, Holger W., additional, and Franzoso, Guido, additional

Published
2018
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5. Clinical proof of concept for a safe and effective NF‐κB‐targeting strategy in multiple myeloma.

Author

Tornatore, Laura, Capece, Daria, D'Andrea, Daniel, Begalli, Federica, Verzella, Daniela, Bennett, Jason, Bannoo, Selina, Franzoso, Guido, Chambery, Angela, Oblak, Metod, Al‐Obaidi, Magda J., Gabriel, Ian, Kaczmarski, Richard S., Oakervee, Heather E., Kaiser, Martin F., Wechalekar, Ashutosh, Benjamin, Reuben, Apperley, Jane F., Auner, Holger W., and Acton, Gary

Subjects
MULTIPLE myeloma, PROOF of concept
Abstract

The article focuses on the efficiency of the nuclear factor (NF)-ΚB pathway in the treatment of multiple myeloma (MM). It talks about the pathway treatment strategy despite being efficient has not yet been approved in the pharmaceutical industry due to the associated toxicities. It tells about alternative agents like the immunomodulatory drugs and proteasome inhibitors are unable to specifically target the cancer cells in the body.

Published
2019
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6. Cancer-Selective Targeting of the NF-κB Survival Pathway in Multiple Myeloma with the GADD45β/MKK7 Inhibitor, DTP3

Author

Tornatore, Laura, primary, Acton, Gary, additional, Adams, Nigel, additional, Campbell, Elizabeth A, additional, Kelly, James, additional, Szydlo, Richard M, additional, Tarbit, Mike, additional, Bannoo, Salina, additional, D'Andrea, Daniel, additional, Capece, Daria, additional, Sandomenico, Annamaria, additional, Dyson, Julian, additional, Leonardi, Antonio, additional, Driessen, Christoph, additional, Ruvo, Menotti, additional, Anees, Ishara, additional, Oblak, Metod, additional, Quaid, Sheena, additional, Al-Obaidi, Magda J, additional, Auner, Holger, additional, Benbenjamin, Reuben, additional, Kaczmarski, Richard S, additional, Kaiser, Martin F, additional, Mehta, Atul, additional, Oakervee, Heather E, additional, Schey, Stephen A, additional, Wechalekar, Ashutosh, additional, Apperley, Jane F., additional, and Franzoso, Guido, additional

Published
2015
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7. Clinical proof of concept for a safe and effective NF-κB-targeting strategy in multiple myeloma

Author

Metod Oblak, Daria Capece, Jane F. Apperley, Jason Bennett, Heather Oakervee, Ashutosh D. Wechalekar, Michael Tarbit, Angela Chambery, Richard Kaczmarski, Domenico Raimondo, Daniela Verzella, Ian H Gabriel, Annamaria Sandomenico, Magda J Al-Obaidi, Daniel D'Andrea, Gary Acton, Menotti Ruvo, James Kelly, Guido Franzoso, Holger W. Auner, Federica Begalli, Antonio Leonardi, Reuben Benjamin, Nigel Adams, Martin Kaiser, Elizabeth A. Campbell, Laura Tornatore, Selina Bannoo, Tornatore, Laura, Capece, Daria, D'Andrea, Daniel, Begalli, Federica, Verzella, Daniela, Bennett, Jason, Acton, Gary, Campbell, Elizabeth A., Kelly, Jame, Tarbit, Michael, Adams, Nigel, Bannoo, Selina, Leonardi, Antonio, Sandomenico, Annamaria, Raimondo, Domenico, Ruvo, Menotti, Chambery, Angela, Oblak, Metod, Al-Obaidi, Magda J., Kaczmarski, Richard S., Gabriel, Ian, Oakervee, Heather E., Kaiser, Martin F., Wechalekar, Ashutosh, Benjamin, Reuben, Apperley, Jane F., Auner, Holger W., and Franzoso, Guido

Subjects
0301 basic medicine, apoptosis, clinical trials, drug, multiple myeloma, NF-κB, Antineoplastic Agents, Cell Line, Tumor, Humans, NF-kappa B, Neoplasm Proteins, Proof of Concept Study, Drug Delivery Systems, Multiple Myeloma, Immunology, Cell Line, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Medicine, 1102 Cardiorespiratory Medicine and Haematology, Multiple myeloma, Tumor, Science & Technology, business.industry, clinical trial, Hematology, medicine.disease, GADD45-BETA, apoptosi, Clinical trial, 030104 developmental biology, chemistry, Apoptosis, Proof of concept, 030220 oncology & carcinogenesis, Cancer research, business, Life Sciences & Biomedicine
Published
2018

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