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This study evaluated whether subclinical myocardial dysfunction occurs in first-degree relatives of patients with idiopathic dilated cardiomyopathy (IDCM), using strain echocardiographic imaging, before apparent left ventricular (LV) failure is observed. The study comprised 77 subjects aged 16–63 years who had first-degree relatives with a previous or new diagnosis of IDCM. LV myocardial deformation parameters of the first-degree relatives with normal LVEF (≥55%) values, as assessed using 2D echocardiography, were evaluated. The findings of the first-degree relatives were compared with an age- and sex-matched control group (n = 86). No difference in terms of age, gender, and body surface area was detected between first-degree relatives and controls. First-degree relatives of IDCM patients had significantly lower LVEF (62.04 ± 5.8% vs. 65.65 ± 6.3%, p

OBJECTIVE Heart failure (HF) has a high prevalence and mortality rate in elderly patients; however, there are few studies that have focused on patients older than 80 years. The aim of this study is to describe and compare the age-specific demographics and clinical features of Turkish elderly patients with HF who were admitted to cardiology clinics. METHODS The Epidemiology of Cardiovascular Disease in Elderly Turkish population (ELDER-TURK) study was conducted in 73 centers in Turkey, and it recruited a total of 5694 patients aged 65 years or older. In this study, the clinical profile of the patients who were aged 80 years or older and those between 65 and 79 years with HF were described and compared based on the ejection fraction (EF)-related classification: HFrEF and HFpEF (is considered as EF: ≥50%). RESULTS A total of 1098 patients (male, 47.5%; mean age, 83.5+-3.1 years) aged ≥80 years and 4596 patients (male, 50.2 %; mean age, 71.1+-4.31 years) aged 65-79 years were enrolled in this study. The prevalence of HF was 39.8% for patients who were ≥80 years and 27.1% for patients 65-79 years old. For patients aged ≥80 years with HF, the prevalence rate was 67% for hypertension (HT), 25.6% for diabetes mellitus (DM), 54.3% for coronary artery disease (CAD), and 42.3% for atrial fibrilation. Female proportion was lower in the HFrEF group (p=0.019). The prevalence of HT and DM was higher in the HFpEF group (p

Summary Objective The level of right ventricular (RV) systolic function has prognostic importance in right ventricular ST-segment elevation myocardial infarction (RV-STEMI). This study aimed to evaluate the changes in RV systolic function in patients with RV-STEMI according to the revascularisation method used for their management. Methods The first group consisted of 132 patients who received primary percutaneous coronary intervention (PPCI). The 78 patients who had received thrombolytic therapy (TT) in external centres before referral to our centre for PCI within three to 12 hours of RV-STEMI were included in the second group. All patients were evaluated by conventional and two-dimensional speckle-tracking echocardiography. Results There were 172 male patients and their mean age was 63.7 ± 11.8 years. There were no significant differences between the two groups with regard to right ventricular systolic parameters at admission and at the one-month follow-up visit. The echocardiographic changes between admission and the one-month follow up were investigated for the patients included in the study groups. Mean values of each parameter observed at the one-month follow up were significantly increased compared to those at admission within each group. Conclusion Our study demonstrated that PCI within three to 12 hours following TT provided similar benefits on right ventricular systolic function compared to PPCI in patients with RV-STEMI.

WOS: 000384427500006, PubMed ID: 27004707, Objective: Atrial functions are relatively suppressed in heart failure (HF). We aimed to investigate the associations of intra-and inter-atrial electromechanical conduction delay (EMCD) with functional class and mortality over a 12-month follow-up period. Methods: The prospective study included 65 patients with systolic HF and 65 healthy subjects with normal sinus rhythm. Left ventricular (LV) systolic functions and left atrial (LA) dimensions and volumes were evaluated by transthoracic echocardiography. Tissue Doppler imaging (TDI) signals at the lateral border of the mitral annulus (lateral PA'), septal mitral annulus (septal PA'), and tricuspid annulus (tricuspid PA') were measured. Intra-and inter-atrial EMCD were calculated. Results: Mitral inflow velocities were studied using pulsed-wave Doppler after placing the sample volume at the leaflets' tips. The peak early (E wave) and late (A wave) velocities were measured. The septal annular E/E' ratio was relatively higher and lateral, septal, and right ventricular S,E', and A' waves were significantly lower in the HF group than in the control group (12.49 +/- 6.03-7.16 +/- 1.75, pE/E'

Renal enfarktüs, literatürde nadiren karşılaşılan bir klinik durum olup, bir çalışmada, tüm acil servis başvurularının yaklaşık % 0,01’ini oluşturduğu belirtilmiştir. Renal enfarktüse ait özgün klinik bulgu ve belirtinin olmaması, benzer klinik tabloya sahip ve daha sık olarak görülen üriner sistem veya diğer karın içi patolojilerle karışmasından dolayı ayırıcı tanıda ilk sıralarda düşünülmemesi düşük insidansın önemli bir nedenidir. Atriyal fibrilasyon, böbreğin de tutulabildiği sistemik (miyokard, beyin veya diğer iç organlarda) arteryel embolizasyona yol açabilmektedir. Yazımızda, mitral darlığı ve kronik atriyal fibrilasyon zemininde bilateral renal enfarktüs gelişen 53 yaşında kadın olgu sunulmuştur., Renal infarction is an uncommon diagnosis with an incidence of about 0.01% of emergency department admissions. It is often mimicked by other more common diseases such as urinary system or other abdominal lesions at clinical presentation. Atrial fibrillation can result in systemic arterial embolism, involving the kidney. With atrial fibrillation, this complication risks are increased. In this report, a 53 year old woman who has bilateral renal infarction diagnosis due to atrial fibrillation is presented.

WOS: 000317783500002, PubMed ID: 22986554, Aim: Inflammation is a critical participant in mediating all stages of cardiovascular disease. Studies related with chitotriosidase that was recently found to be relevant to arterial inflammation. In this study we evaluated activity of serum chitotriosidase in acute coronary syndrome patients and its relationship with cardiovascular events, cardiac enzymes and inflammatory indicators. Methods: We prospectively analyzed consecutive 30 patients with ST-segment elevation myocardial infarction, 30 patients with non ST-segment elevation myocardial infarction, 30 patients with unstable angina pectroris who were admitted to our intensive care unit and 30 healthy people (average age 56.86 +/- 10.44 years, 81 male) between Jaunary and June 2010. Details of baseline clinical characteristics, biochemical values, receiving treatment and basal ECG findings were recorded. Data of patients with coronary angiography were evaluated. Results: Cut off value of chitotriosidase was calculated 82.00 mmol.ml-1.h-1, with 83 percent sensitivity and 72 percent spesificity. The activity of chitotriosidase in acute coronary syndrome group was 88.85 +/- 23.08 mmol.ml-1.h-1, where as the control group was 68.47 +/- 28.44 mmol.ml-1.h-1, respectively p=0.001). The highest activity of chitotriosidase (96.11 +/- 19.77 mmol.ml-1.h-1) was found in ST-segment elevation myocardial infarction group and the minimal activity of chitotriosidase was in the control group (68.47 +/- 28.44 mmol.ml-1.h-1) (p=0.001). The activity of chitotriosidase in ST-segment elevation myocardial infarction and non ST-segment elevation myocardial infarction groups were significantly higher than control group (p=0.001 and p=0.045). When acute coronary syndrome groups compared to control; a positive correlation was found between chitotriosidase activity and hs-CRP (r =0.21, p=0.046), troponin T (r=0.25, p=0.016), creatine kinase-MB (r=0.20, p=0.059). Conclusion: The activity of chitotriosidase is increased in acute coronary syndrome patients. Chitotriosidase is higher in ST-segment elevation myocardial infaction group than non ST-segment elevation myocardial infarction and unstable angina pectoris group., Department of Cardiology and Biochemistry, Funding for this work was obtained from the Department of Cardiology and Biochemistry.

We present a 52-year-old man with swelling, tightness, heaviness, and redness in the right half of his neck, face, upper arm, and right precordial area after repetitive exercises. No etiological factors such as trauma, venous catheter, malignancy, hematologic disorder history, or any chronic disease were noted. A Doppler ultrasound of the upper extremities was performed, which showed a complete thrombotic occlusion in the right internal jugular vein, partial occlusion in the right brachiocephalic and subclavian veins with thrombosis, and chronic thrombosis occluding the left brachial vein. Complete blood cell count, coagulation profiles, and rheumatologic and tumor markers were normal. The patient reported that he had taken spinning classes for the last 18 months, and for the past 4 days he reported that he had done his spinning exercises harder and more frequently. The swelling and redness regressed partially on the 3rd day of therapy with enoxaparin sodium. In the first month follow-up visit we performed a control Doppler ultrasound and it showed partially thrombosed areas in the right brachiocephalic and internal jugular veins. Also, chronic thrombosis persisted in the left brachial and basilic veins. Computed tomography images showed no evidence for malignancy and some sections showed filling defects in the vena cava superior, which was attributed to thrombotic materials. The patient was successfully treated with anticoagulants for 6 months.

29th Turkish Cardiology Congress of the Turkish-Society-of-Cardiology (TSC) with International Participation -- OCT 26-29, 2013 -- Antalya, TURKEY, WOS: 000329858400006, Turkish Soc Cardiol