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1. A Unified Strategy for the Asymmetric Synthesis of Highly Substituted 1,2-Amino Alcohols Leading to Highly Substituted Bisoxazoline Ligands

Author

Scott E. Denmark, Casey L. Olen, Yang Wang, Bijay Shrestha, Adon C. Kwong, Aaron Roth, and Brennan T. Rose

Subjects
010405 organic chemistry, Chemistry, Organic Chemistry, Enantioselective synthesis, Stereoisomerism, Ligands, 010402 general chemistry, Amino Alcohols, 01 natural sciences, Combinatorial chemistry, 0104 chemical sciences, Yield (chemistry), Indicators and Reagents, Imines
Abstract

A general procedure for the asymmetric synthesis of highly substituted 1,2-amino alcohols in high yield and diastereoselectivity is described that uses organometallic additions of a wide range of nucleophiles to

Published
2021
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