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A Unified Strategy for the Asymmetric Synthesis of Highly Substituted 1,2-Amino Alcohols Leading to Highly Substituted Bisoxazoline Ligands

Authors :
Scott E. Denmark
Casey L. Olen
Yang Wang
Bijay Shrestha
Adon C. Kwong
Aaron Roth
Brennan T. Rose
Source :
The Journal of Organic Chemistry. 86:3490-3534
Publication Year :
2021
Publisher :
American Chemical Society (ACS), 2021.

Abstract

A general procedure for the asymmetric synthesis of highly substituted 1,2-amino alcohols in high yield and diastereoselectivity is described that uses organometallic additions of a wide range of nucleophiles to

Details

ISSN :
15206904 and 00223263
Volume :
86
Database :
OpenAIRE
Journal :
The Journal of Organic Chemistry
Accession number :
edsair.doi.dedup.....a5ac603ddcf819ade3001b1eb57337f8
Full Text :
https://doi.org/10.1021/acs.joc.0c02899