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125 results on '"Adeoye, Abiodun M"'

1. ACHIEVE conference proceedings: implementing action plans to reduce and control hypertension burden in Africa

Author

Olowoyo, Paul, Dzudie, Anastase, Okekunle, Akinkunmi Paul, Obiako, Reginald, Mocumbi, Ana, Beheiry, Hind, Parati, Gianfranco, Lackland, Daniel T., Sarfo, Fred S., Odili, Augustine, Adeoye, Abiodun M., Wahab, Kolawole, Agyemang, Charles, Campbell, Norman, Kengne, Andre Pascal, Whelton, Paul K., Pellicori, Pierpaolo, Ebenezer, Ad Adams, Adebayo, Oladimeji, Olalusi, Oladotun, Jegede, Ayodele, Uvere, Ezinne, Adebajo, Olayinka, Awuah, Baffour, Moran, Andrew, Williams, Bryan, Guzik, Tomasz J., Kokuro, Collins, Bukachi, Fred, Ogah, Okechukwu S., Delles, Christian, Maffia, Pasquale, Akinyemi, Rufus, Barango, Prebo, Ojji, Dike, and Owolabi, Mayowa

Published
2024
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2. Clinical and neuroimaging factors associated with 30-day fatality among indigenous West Africans with spontaneous intracerebral hemorrhage

Author

Komolafe, Morenikeji A., Sunmonu, Taofiki, Akinyemi, Joshua, Sarfo, Fred S., Akpalu, Albert, Wahab, Kolawole, Obiako, Reginald, Owolabi, Lukman, Osaigbovo, Godwin O., Ogbole, Godwin, Tiwari, Hemant K., Jenkins, Carolyn, Lackland, Daniel T., Fakunle, Adekunle G., Uvere, Ezinne, Akpa, Onoja, Dambatta, Hamisu A., Akpalu, Josephine, Onasanya, Akinola, Olaleye, Adeniji, Ogah, Okechukwu S., Isah, Sulaiman Y., Fawale, Micheal B., Adebowale, Akintunde, Okekunle, Akinkunmi P., Arnett, Donna, Adeoye, Abiodun M., Agunloye, Atinuke M., Bello, Abiodun H., Aderibigbe, Adeniyi S., Idowu, Ahmed O., Sanusi, Ahmad A., Ogunmodede, Adebimpe, Balogun, Simon A., Egberongbe, Adedeji A., Rotimi, Folorunso T., Fredrick, Adeyemi, Akinnuoye, Andrew O., Adeniyi, Folu A., Calys-Tagoe, Benedict, Adebayo, Philip, Arulogun, Oyedunni, Agbogu-Ike, Obiageli U., Yaria, Joseph, Appiah, Lambert, Ibinaiye, Philip, Singh, Arti, Adeniyi, Sunday, Olalusi, Oladotun, Mande, Aliyu, Balogun, Olayemi, Akinyemi, Rufus, Ovbiagele, Bruce, and Owolabi, Mayowa

Published
2024
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3. Patient-level and system-level determinants of stroke fatality across 16 large hospitals in Ghana and Nigeria: a prospective cohort study

Author

Sarfo, Fred S, Akpa, Onoja M, Ovbiagele, Bruce, Akpalu, Albert, Wahab, Kolawole, Obiako, Reginald, Komolafe, Morenikeji, Owolabi, Lukman, Ogbole, Godwin, Fakunle, Adekunle, Okekunle, Akinkunmi Paul, Asowata, Osahon J, Calys-Tagoe, Benedict, Uvere, Ezinne O, Sanni, Taofeek, Olowookere, Samuel, Ibinaiye, Philip, Akinyemi, Joshua O, Arulogun, Oyedunni, Jenkins, Carolyn, Lackland, Daniel T, Tiwari, Hemant K, Isah, Suleiman Y, Abubakar, Sani A, Oladimeji, Adebayo, Adebayo, Philip, Akpalu, Josephine, Onyeonoro, Ugochukwu, Ogunmodede, James A, Akisanya, Cynthia, Mensah, Yaw, Oyinloye, Olalekan I, Appiah, Lambert, Agunloye, Atinuke M, Osaigbovo, Godwin O, Adeoye, Abiodun M, Adeleye, Osimhiarherhuo Ohifemen, Laryea, Ruth Y, Olunuga, Taiwo, Ogah, Okechukwu S, Oguike, Wisdom, Ogunronbi, Mayowa, Adeniyi, Wasiu, Olugbo, Obiabo Y, Bello, Abiodun H, Ogunjimi, Luqman, Diala, Samuel, Dambatta, Hamisu A, Singh, Arti, Adamu, Sheila, Obese, Vida, Adusei, Nathaniel, Owusu, Dorcas, Ampofo, Michael, Tagge, Raelle, Fawale, Bimbo, Yaria, Joseph, Akinyemi, Rufus O, and Owolabi, Mayowa O

Published
2023
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4. Are there differences in perceptions, preferences and attitudes towards disclosure of genetic testing for Stroke? A qualitative study among stroke-free SIREN-SIBS genomics study participants

Author

Arulogun, Oyedunni, Nichols, Michelle, Jenkins, Carolyn, Fakunle, Adekunle Gregory, Akpa, Onoja, Sarfo, Fred S., Akpalu, Albert, Wahab, Kolawole, Obiako, Reginald, Komolafe, Morenikeji, Owolabi, Lukman, Osaigbovo, Godwin O., Okekunle, Akinkunmi Paul, Akinyemi, Joshua, Ogbole, Godwin, Calys-Tagoe, Benedict, Adeleye, Adeniji, Mensah, Yaw, Asowata, Osahon Jeffery, Adeoye, Abiodun M., Appiah, Lambert, Singh, Arti, Adebayo, Philip, Arnett, Donna, Tiwari, Hemant K., Lackland, Daniel, Ibinaiye, Philip, Oguike, Wisdom, Melikam, Chimdinma, Sunday, Adeniyi, Bello, Abiodun, Ogah, Okechukwu, Akinyemi, Rufus, Ovbiagele, Bruce, and Owolabi, Mayowa

Published
2023
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5. Determinants of metabolic syndrome and its prognostic implications among stroke patients in Africa: Findings from the Stroke Investigative Research and Educational Network (SIREN) study

Author

Adeoye, Abiodun M., Akintunde, Adeseye A., Akinyemi, Joshua, Fakunle, Adekunle G., Sarfo, Fred S., Akpalu, Albert, Wahab, Kolawole, Obiako, Reginald, Komolafe, Morenikeji, Owolabi, Lukman, Osaigbovo, Godwin O., Akpa, Onoja, Arulogun, Oyedunni, Okekunle, Akinkunmi P., Ogah, Okechukwu S., Jenkins, Carolyn, Ogbole, Godwin, Tiwari, Hemant K., Asowata, Osahon J., Ibinaiye, Philip, Appiah, Lambert, Agunloye, Atinuke M., Yaria, Joseph, Calys-Tagoe, Benedict, Agbogu-Ike, Obiageli U., Adeniyi, Sunday, Adebayo, Philip, Balogun, Olayemi, Aderonmu, Olajumoke, Adeegbe, Oluwayemisi T., Adebayo, Oladimeji, Akinyemi, Rufus, Ovbiagele, Bruce, and Owolabi, Mayowa

Published
2022
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6. How adults in selected urban and rural communities in southwest Nigeria perceive cardiovascular disease, risk factors, and their risk status: a critical factor in preventing and managing cardiovascular disease

Author

Awosoga, Olu, Odunaiya, Nse A., Odole, Adesola C., Adegoke, Opeyemi M., Adeoye, Abiodun M., Oyewole, Olufemi O., Aweto, Happiness A., Onyeso, Ogochukwu K., Alumona, Chiedozie J., Awosoga, Olu, Odunaiya, Nse A., Odole, Adesola C., Adegoke, Opeyemi M., Adeoye, Abiodun M., Oyewole, Olufemi O., Aweto, Happiness A., Onyeso, Ogochukwu K., and Alumona, Chiedozie J.

Published
2024

7. A Novel Afrocentric Stroke Risk Assessment Score: Models from the Siren Study

Author

Akpa, Onoja, Sarfo, Fred S., Owolabi, Mayowa, Akpalu, Albert, Wahab, Kolawole, Obiako, Reginald, Komolafe, Morenikeji, Owolabi, Lukman, Osaigbovo, Godwin O., Ogbole, Godwin, Tiwari, Hemant K., Jenkins, Carolyn, Fakunle, Adekunle G., Olowookere, Samuel, Uvere, Ezinne O., Akinyemi, Joshua, Arulogun, Oyedunni, Akpalu, Josephine, Tito-Ilori, Moyinoluwalogo M., Asowata, Osahon J., Ibinaiye, Philip, Akisanya, Cynthia, Oyinloye, Olalekan I., Appiah, Lambert, Sunmonu, Taofik, Olowoyo, Paul, Agunloye, Atinuke M., Adeoye, Abiodun M., Yaria, Joseph, Lackland, Daniel T., Arnett, Donna, Laryea, Ruth Y., Adigun, Taiwo O., Okekunle, Akinkunmi P., Calys-Tagoe, Benedict, Ogah, Okechukwu S., Ogunronbi, Mayowa, Obiabo, Olugbo Y., Isah, Suleiman Y., Dambatta, Hamisu A., Tagge, Raelle, Ogenyi, Obande, Fawale, Bimbo, Melikam, Chimdinma L., Onasanya, Akinola, Adeniyi, Sunday, Akinyemi, Rufus, and Ovbiagele, Bruce

Published
2021
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8. Non-cigarette Tobacco Use and Stroke Among West Africans: Evidence From the SIREN Study.

Author

Fakunle, Adekunle Gregory, Okekunle, Akinkunmi Paul, Asowata, Osahon Jeffery, Akpa, Onoja, Sarfo, Fred S, Akpalu, Albert, Wahab, Kolawole, Obiako, Reginald, Komolafe, Morenikeji, Owolabi, Lukman, Osaigbovo, Godwin O, Adeoye, Abiodun M, Tiwari, Hemant K, Uvere, Ezinne O, Akinyemi, Joshua, Jenkins, Carolyn, Arulogun, Oyedunni, Ibinaiye, Philip, Appiah, Lambert T, and Bello, Temilade

Subjects
TOBACCO use, MAGNETIC resonance imaging, COMPUTED tomography, SYMPTOMS, STROKE
Abstract

Introduction Non-cigarette tobacco (NCT) represents a form of tobacco use with a misperceived significance in chronic disease events. Whether NCT use is sufficient to promote stroke events, especially among Africans, is yet to be understood. This study assessed the relationship between NCT use and stroke among indigenous Africans. Methods A total of 7617 respondents (NCT users: 41 vs. non-NCT: 7576) from the Stroke Investigative Research and Educational Network (SIREN) study were included in the current analysis. NCT use was defined as self-reported use of smoked (cigars or piper) or smokeless (snuff or chewed) tobacco in the past year preceding stroke events. Stroke was defined based on clinical presentation and confirmed with a cranial computed tomography/magnetic resonance imaging. Multivariable-adjusted logistic regression was applied to estimate the odds ratio (OR) and 95% confidence interval (CI) for the relationship of NCT with stroke at a two-sided p <.05. Results Out of the 41 (0.54%) who reported NCT use, 27 (65.9%) reported using smokeless NCT. NCT users were older than non-NCT users (62.8 ± 15.7 vs. 57.7 ± 14.8 years). Overall, NCT use was associated with first-ever stroke (OR: 2.08; 95% CI: 1.02, 4.23) in the entire sample. Notably, smokeless NCT use was independently associated with higher odds of stroke (OR: 2.74; 95% CI: 1.15, 6.54), but smoked NCT use (OR: 0.16; 95% CI: 0.02, 1.63) presented a statistically insignificant association after adjusting for hypertension and other covariates. Conclusions NCT use was associated with higher odds of stroke, and public health interventions targeting NCT use might be promising in reducing the burden of stroke among indigenous Africans. Implications A detailed understanding of the relationship between NCT use and stroke will likely inform well-articulated policy guidance and evidence-based recommendations for public health prevention and management of stroke on the African continent. [ABSTRACT FROM AUTHOR]

Published
2024
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9. Clinical and neuroimaging factors associated with 30-day fatality among indigenous West Africans with spontaneous intracerebral hemorrhage

Author

Komolafe, Morenikeji A., primary, Sunmonu, Taofiki, additional, Akinyemi, Joshua, additional, Sarfo, Fred S., additional, Akpalu, Albert, additional, Wahab, Kolawole, additional, Obiako, Reginald, additional, Owolabi, Lukman, additional, Osaigbovo, Godwin O., additional, Ogbole, Godwin, additional, Tiwari, Hemant K., additional, Jenkins, Carolyn, additional, Lackland, Daniel T., additional, Fakunle, Adekunle G., additional, Uvere, Ezinne, additional, Akpa, Onoja, additional, Dambatta, Hamisu A., additional, Akpalu, Josephine, additional, Onasanya, Akinola, additional, Olaleye, Adeniji, additional, Ogah, Okechukwu S., additional, Isah, Sulaiman Y., additional, Fawale, Micheal B., additional, Adebowale, Akintunde, additional, Okekunle, Akinkunmi P., additional, Arnett, Donna, additional, Adeoye, Abiodun M., additional, Agunloye, Atinuke M., additional, Bello, Abiodun H., additional, Aderibigbe, Adeniyi S., additional, Idowu, Ahmed O., additional, Sanusi, Ahmad A., additional, Ogunmodede, Adebimpe, additional, Balogun, Simon A., additional, Egberongbe, Adedeji A., additional, Rotimi, Folorunso T., additional, Fredrick, Adeyemi, additional, Akinnuoye, Andrew O., additional, Adeniyi, Folu A., additional, Calys-Tagoe, Benedict, additional, Adebayo, Philip, additional, Arulogun, Oyedunni, additional, Agbogu-Ike, Obiageli U., additional, Yaria, Joseph, additional, Appiah, Lambert, additional, Ibinaiye, Philip, additional, Singh, Arti, additional, Adeniyi, Sunday, additional, Olalusi, Oladotun, additional, Mande, Aliyu, additional, Balogun, Olayemi, additional, Akinyemi, Rufus, additional, Ovbiagele, Bruce, additional, and Owolabi, Mayowa, additional

Published
2023
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10. Non-cigarette Tobacco Use and Stroke Among West Africans: Evidence From the SIREN Study

Author

Fakunle, Adekunle Gregory, primary, Okekunle, Akinkunmi Paul, additional, Asowata, Osahon Jeffery, additional, Akpa, Onoja, additional, Sarfo, Fred S, additional, Akpalu, Albert, additional, Wahab, Kolawole, additional, Obiako, Reginald, additional, Komolafe, Morenikeji, additional, Owolabi, Lukman, additional, Osaigbovo, Godwin O, additional, Adeoye, Abiodun M, additional, Tiwari, Hemant K, additional, Uvere, Ezinne O, additional, Akinyemi, Joshua, additional, Jenkins, Carolyn, additional, Arulogun, Oyedunni, additional, Ibinaiye, Philip, additional, Appiah, Lambert T, additional, Bello, Temilade, additional, Singh, Arti, additional, Yaria, Joseph, additional, Calys-Tagoe, Benedict, additional, Ogbole, Godwin, additional, Chukwuonye, Ijezie, additional, Melikam, Chidinma, additional, Adebayo, Philip, additional, Mensah, Yaw, additional, Adebayo, Oladimeji, additional, Adeniyi, Sunday, additional, Oguike, Wisdom, additional, Donna, Arnett, additional, Akinyemi, Rufus, additional, Ovbiagele, Bruce, additional, and Owolabi, Mayowa, additional

Published
2023
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11. Risk Factor Characterization of Ischemic Stroke Subtypes Among West Africans

Author

Sarfo, Fred S., Ovbiagele, Bruce, Akpa, Onoja, Akpalu, Albert, Wahab, Kolawole, Obiako, Reginald, Komolafe, Morenikeji, Owolabi, Lukman, Ogbole, Godwin, Calys-Tagoe, Benedict, Fakunle, Adekunle, Sanni, Taofeek, Mulugeta, Gebregziabher, Abdul, Salaam, Akintunde, Adeseye A., Olowookere, Samuel, Uvere, Ezinne O., Ibinaiye, Philip, Akinyemi, Joshua, Uwanuruochi, Kelechukwu, Olayemi, Balogun, Odunlami, Olufemi A., Abunimye, Esther, Arulogun, Oyedunni, Isah, Suleiman Y., Abubakar, Sani A., Oladimeji, Adebayo, Adebayo, Philip, Shidali, Vincent, Chukwuonye, Innocent I., Akpalu, Josephine, Tito-Ilori, Moyinoluwalogo M., Asowata, Osahon J., Sanya, Emmanuel O., Amusa, Ganiyu, Onyeonoro, Ugochukwu, Ogunmodede, James A., Sule, Abdullateef G., Akisanya, Cynthia, Mensah, Yaw, Oyinloye, Olalekan I., Appiah, Lambert, Agunloye, Atinuke M., Osaigbovo, Godwin O., Olabinri, Eunice, Kolo, Philip M., Okeke, Obiora, Adeoye, Abiodun M., Ajose, Olabamiji, Jenkins, Carolyn, Lackland, Daniel T., Egberongbe, Adedeji A., Adeniji, Olaleye, Ohifemen Adeleye, Osimhiarherhuo, Tiwari, Hemant K., Arnett, Donna, Laryea, Ruth Y., Olunuga, Taiwo, Akinwande, Kazeem S., Imoh, Lucius, Ogah, Okechukwu S., Melikam, Ezinne S., Adebolaji, Adeyemo, Oguike, Wisdom, Ogunronbi, Olumayowa, Adeniyi, Wasiu, Olugbo, Obiabo Y., Bello, Abiodun H., Ohagwu, Kenneth A., Ogunjimi, Luqman, Agyekum, Francis, Iheonye, Henry, Adesina, Julius, Diala, Samuel, Dambatta, Hamisu A., Ikubor, Joyce, Singh, Arti, Adamu, Sheila, Obese, Vida, Adusei, Nathaniel, Owusu, Dorcas, Ampofo, Michael, Tagge, Raelle, Efidi, Richard, Fawale, Bimbo, Yaria, Joseph, Akinyemi, Rufus, and Owolabi, Mayowa

Published
2021
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12. Correction to: African Control of Hypertension through Innovative Epidemiology and a Vibrant Ecosystem (ACHIEVE): novel strategies for accelerating hypertension control in Africa

Author

Owolabi, Mayowa, primary, Olowoyo, Paul, additional, Mocumbi, Ana, additional, Ogah, Okechukwu S., additional, Odili, Augustine, additional, Wahab, Kolawole, additional, Ojji, Dike, additional, Adeoye, Abiodun M., additional, Akinyemi, Rufus, additional, Akpalu, Albert, additional, Obiako, Reginald, additional, Sarfo, Fred S., additional, Bavuma, Charlotte, additional, Beheiry, Hind Mamoun, additional, Ibrahim, Moshen, additional, El Aroussy, Wafaa, additional, Parati, Gianfranco, additional, Dzudie, Anastase, additional, Singh, Sandhya, additional, Akpa, Onoja, additional, Kengne, Andre Pascal, additional, Okekunle, Akinkunmi Paul, additional, de Graft Aikins, Ama, additional, Agyemang, Charles, additional, Ogedegbe, Gbenga, additional, Ovbiagele, Bruce, additional, Garg, Renu, additional, Campbell, Norman R. C., additional, Lackland, Daniel T., additional, Barango, Prebo, additional, Slama, Slim, additional, Varghese, Cherian V., additional, Whelton, Paul K., additional, and Zhang, Xin-Hua, additional

Published
2023
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13. African Control of Hypertension through Innovative Epidemiology and a Vibrant Ecosystem (ACHIEVE): novel strategies for accelerating hypertension control in Africa

Author

Owolabi, Mayowa, primary, Olowoyo, Paul, additional, Mocumbi, Ana, additional, Ogah, Okechukwu S., additional, Odili, Augustine, additional, Wahab, Kolawole, additional, Ojji, Dike, additional, Adeoye, Abiodun M., additional, Akinyemi, Rufus, additional, Akpalu, Albert, additional, Obiako, Reginald, additional, Sarfo, Fred S., additional, Bavuma, Charlotte, additional, Beheiry, Hind Mamoun, additional, Ibrahim, Moshen, additional, El Aroussy, Wafaa, additional, Parati, Gianfranco, additional, Dzudie, Anastase, additional, Singh, Sandhya, additional, Akpa, Onoja, additional, Kengne, Andre Pascal, additional, Okekunle, Akinkunmi Paul, additional, de Graft Aikins, Ama, additional, Agyemang, Charles, additional, Ogedegbe, Gbenga, additional, Ovbiagele, Bruce, additional, Garg, Renu, additional, Campbell, Norman R. C., additional, Lackland, Daniel T., additional, Barango, Prebo, additional, Slama, Slim, additional, Varghese, Cherian V., additional, Whelton, Paul K., additional, and Zhang, Xin-Hua, additional

Published
2023
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14. African Control of Hypertension through Innovative Epidemiology and a Vibrant Ecosystem (ACHIEVE): novel strategies for accelerating hypertension control in Africa

Author

Owolabi, Mayowa, Olowoyo, Paul, Mocumbi, Ana, Ogah, Okechukwu S., Odili, Augustine, Wahab, Kolawole, Ojji, Dike, Adeoye, Abiodun M., Akinyemi, Rufus, Akpalu, Albert, Obiako, Reginald, Sarfo, Fred S., Bavuma, Charlotte, Beheiry, Hind Mamoun, Ibrahim, Moshen, El Aroussy, Wafaa, Parati, Gianfranco, Dzudie, Anastase, Singh, Sandhya, Akpa, Onoja, Kengne, Andre Pascal, Okekunle, Akinkunmi Paul, de Graft Aikins, Ama, Agyemang, Charles, Ogedegbe, Gbenga, Ovbiagele, Bruce, Garg, Renu, Campbell, Norman R. C., Lackland, Daniel T., Barango, Prebo, Slama, Slim, Varghese, Cherian V., Whelton, Paul K., and Zhang, Xin-Hua

Abstract

Hypertension is a leading preventable and controllable risk factor for cardiovascular and cerebrovascular diseases and the leading preventable risk for death globally. With a prevalence of nearly 50% and 93% of cases uncontrolled, very little progress has been made in detecting, treating, and controlling hypertension in Africa over the past thirty years. We propose the African Control of Hypertension through Innovative Epidemiology and a Vibrant Ecosystem (ACHIEVE) to implement the HEARTS package for improved surveillance, prevention, treatment/acute care of hypertension, and rehabilitation of those with hypertension complications across the life course. The ecosystem will apply the principles of an iterative implementation cycle by developing and deploying pragmatic solutions through the contextualization of interventions tailored to navigate barriers and enhance facilitators to deliver maximum impact through effective communication and active participation of all stakeholders in the implementation environment. Ten key strategic actions are proposed for implementation to reduce the burden of hypertension in Africa.

Published
2024
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16. Secondhand smoke exposure is independently associated with stroke among non-smoking adults in West Africa

Author

Okekunle, Akinkunmi Paul, primary, Asowata, Osahon Jeffery, additional, Fakunle, Adekunle G., additional, Akpa, Onoja Matthew, additional, Sarfo, Fred S., additional, Akpalu, Albert, additional, Wahab, Kolawole, additional, Obiako, Reginald, additional, Komolafe, Morenikeji, additional, Owolabi, Lukman, additional, Osaigbovo, Godwin O., additional, Tiwari, Hemant K., additional, Akinyemi, Joshua, additional, Jenkins, Carolyn, additional, Arulogun, Oyedunni, additional, Ibinaiye, Philip, additional, Appiah, Lambert, additional, Agunloye, Atinuke M., additional, Adeoye, Abiodun M., additional, Yaria, Joseph, additional, Calys-Tagoe, Benedict, additional, Uvere, Ezinne O., additional, Ogbole, Godwin, additional, Agyekum, Francis, additional, Sanni, Taofeek A., additional, Amusa, Ganiyu A., additional, Ogunronbi, Mayowa, additional, Olowookere, Samuel, additional, Balogun, Olayemi, additional, Ogunmodede, James A., additional, Olalusi, Oladotun V., additional, Samuel, Diala, additional, Mande, Aliyu, additional, Rabiu, Musbahu, additional, Adebayo, Philip, additional, Sunday, Adeniyi, additional, Imoh, Lucius Chidiebere, additional, Oguntade, Ayodipupo S., additional, Ajose, Abiodun, additional, Singh, Arti, additional, Adeegbe, Oluwayemisi T., additional, Mensah, Yaw, additional, Fawale, Michael B., additional, Abdul, Salaam, additional, Ikubor, Joyce, additional, Tolulope, Afolaranmi, additional, Yahaya, Isah S., additional, Akisanya, Cynthia, additional, Odo, Chidi J., additional, Efidi, Richard, additional, Chukwuonye, Innocent I., additional, Shidali, Vincent, additional, Adebowale, Akintunde, additional, Ohagwu, Kenneth A., additional, Adeleye, Osimhiarherhuo O., additional, Iheonye, Henry, additional, Akintunde, Adeseye, additional, Olabinri, Eunice, additional, Akpalu, Josephine, additional, Adesina, Julius, additional, Onyeonoro, Ugochukwu, additional, Onasanya, Akinola, additional, Arnett, Donna K., additional, Lackland, Daniel, additional, Akinyemi, Rufus, additional, Ovbiagele, Bruce, additional, and Owolabi, Mayowa, additional

Published
2022
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17. Frequent vegetable consumption is inversely associated with hypertension among indigenous Africans

Author

Akpa, Onoja Matthew, primary, Okekunle, Akinkunmi Paul, additional, Asowata, Osahon Jeffery, additional, Chikowore, Tinashe, additional, Mohamed, Shukri F, additional, Sarfo, Fred, additional, Akinyemi, Rufus, additional, Akpalu, Albert, additional, Wahab, Kolawole, additional, Obiako, Reginald, additional, Komolafe, Morenikeji, additional, Owolabi, Lukman, additional, Osaigbovo, Godwin O, additional, Ogbole, Godwin, additional, Tiwari, Hemant K, additional, Akinyemi, Joshua, additional, Fakunle, Adekunle, additional, Uvere, Ezinne, additional, Adeoye, Abiodun M, additional, Lackland, Daniel, additional, Arnett, Donna K, additional, Ovbiagele, Bruce, additional, Ramsay, Michèle, additional, and Owolabi, Mayowa, additional

Published
2022
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18. Stroke genetics informs drug discovery and risk prediction across ancestries

Author

Mishra, Aniket, Malik, Rainer, Hachiya, Tsuyoshi, Jurgenson, Tuuli, Namba, Shinichi, Posner, Daniel C, Kamanu, Frederick K, Koido, Masaru, Le Grand, Quentin, Shi, Mingyang, He, Yunye, Georgakis, Marios K, Caro, Ilana, Krebs, Kristi, Liaw, Yi-Ching, Vaura, Felix C, Lin, Kuang, Winsvold, Bendik Slagsvold, Srinivasasainagendra, Vinodh, Parodi, Livia, Bae, Hee-Joon, Chauhan, Ganesh, Chong, Michael R, Tomppo, Liisa, Akinyemi, Rufus, Roshchupkin, Gennady V, Habib, Naomi, Jee, Yon Ho, Thomassen, Jesper Qvist, Abedi, Vida, Carcel-Marquez, Jara, Nygaard, Marianne, Leonard, Hampton L, Yang, Chaojie, Yonova-Doing, Ekaterina, Knol, Maria J, Lewis, Adam J, Judy, Renae L, Ago, Tetsuro, Amouyel, Philippe, Armstrong, Nicole D, Bakker, Mark K, Bartz, Traci M, Bennett, David A, Bis, Joshua C, Bordes, Constance, Borte, Sigrid, Cain, Anael, Ridker, Paul M, Cho, Kelly, Chen, Zhengming, Cruchaga, Carlos, Cole, John W, de Jager, Phil L, de Cid, Rafael, Endres, Matthias, Ferreira, Leslie E, Geerlings, Mirjam I, Gasca, Natalie C, Gudnason, Vilmundur, Hata, Jun, He, Jing, Heath, Alicia K, Ho, Yuk-Lam, Havulinna, Aki S, Hopewell, Jemma C, Hyacinth, Hyacinth I, Inouye, Michael, Jacob, Mina A, Jeon, Christina E, Jern, Christina, Kamouchi, Masahiro, Keene, Keith L, Kitazono, Takanari, Kittner, Steven J, Konuma, Takahiro, Kumar, Amit, Lacaze, Paul, Launer, Lenore J, Lee, Keon-Joo, Lepik, Kaido, Li, Jiang, Li, Liming, Manichaikul, Ani, Markus, Hugh S, Marston, Nicholas A, Meitinger, Thomas, Mitchell, Braxton D, Montellano, Felipe A, Morisaki, Takayuki, Mosley, Thomas H, Nalls, Mike A, Nordestgaard, Borge G, O'Donnell, Martin J, Okada, Yukinori, Onland-Moret, N Charlotte, Ovbiagele, Bruce, Peters, Annette, Psaty, Bruce M, Rich, Stephen S, Rosand, Jonathan, Sabatine, Marc S, Sacco, Ralph L, Saleheen, Danish, Sandset, Else Charlotte, Salomaa, Veikko, Sargurupremraj, Muralidharan, Sasaki, Makoto, Satizabal, Claudia L, Schmidt, Carsten O, Shimizu, Atsushi, Smith, Nicholas L, Sloane, Kelly L, Sutoh, Yoichi, Sun, Yan V, Tanno, Kozo, Tiedt, Steffen, Tatlisumak, Turgut, Torres-Aguila, Nuria P, Tiwari, Hemant K, Tregouet, David-Alexandre, Trompet, Stella, Tuladhar, Anil Man, Tybjaerg-Hansen, Anne, van Vugt, Marion, Vibo, Riina, Verma, Shefali S, Wiggins, Kerri L, Wennberg, Patrik, Woo, Daniel, Wilson, Peter WF, Xu, Huichun, Yang, Qiong, Yoon, Kyungheon, Lee, Jin-Moo, Cheng, Yu-Ching, Meschia, James F, Chen, Wei Min, Sale, Michele M, Zonderman, Alan B, Evans, Michele K, Wilson, James G, Correa, Adolfo, Traylor, Matthew, Lewis, Cathryn M, Carty, Cara L, Reiner, Alexander, Haessler, Jeffrey, Langefeld, Carl D, Gottesman, Rebecca F, Yaffe, Kristine, Liu, Yong Mei, Kooperberg, Charles, Lange, Leslie A, Furie, Karen L, Arnett, Donna K, Benavente, Oscar R, Grewal, Raji P, Peddareddygari, Leema Reddy, Hveem, Kristian, Lindstrom, Sara, Wang, Lu, Smith, Erin N, Gordon, William, van Hylckama Vlieg, Astrid, de Andrade, Mariza, Brody, Jennifer A, Pattee, Jack W, Brumpton, Ben M, Suchon, Pierre, Chen, Ming-Huei, Frazer, Kelly A, Turman, Constance, Germain, Marine, MacDonald, James, Braekkan, Sigrid K, Armasu, Sebastian M, Pankratz, Nathan, Jackson, Rebecca D, Nielsen, Jonas B, Giulianini, Franco, Puurunen, Marja K, Ibrahim, Manal, Heckbert, Susan R, Bammler, Theo K, McCauley, Bryan M, Taylor, Kent D, Pankow, James S, Reiner, Alexander P, Gabrielsen, Maiken E, Deleuze, Jean-Francois, O'Donnell, Chris J, Kim, Jihye, McKnight, Barbara, Kraft, Peter, Hansen, John-Bjarne, Rosendaal, Frits R, Heit, John A, Tang, Weihong, Morange, Pierre-Emmanuel, Johnson, Andrew D, Kabrhel, Christopher, van Dijk, Ewoud J, Koudstaal, Peter J, Luijckx, Gert-Jan, Nederkoorn, Paul J, van Oostenbrugge, Robert J, Visser, Marieke C, Wermer, Marieke JH, Kappelle, L Jaap, Esko, Tonu, Metspalu, Andres, Magi, Reedik, Nelis, Mari, Irvin, Marguerite R, de Leeuw, Frank-Erik, Levi, Christopher R, Maguire, Jane, Jimenez-Conde, Jordi, Sharma, Pankaj, Sudlow, Cathie LM, Rannikmae, Kristiina, Schmidt, Reinhold, Slowik, Agnieszka, Pera, Joanna, Thijs, Vincent NS, Lindgren, Arne G, Ilinca, Andreea, Melander, Olle, Engstrom, Gunnar, Rexrode, Kathryn M, Rothwell, Peter M, Stanne, Tara M, Johnson, Julie A, Danesh, John, Butterworth, Adam S, Heitsch, Laura, Boncoraglio, Giorgio B, Kubo, Michiaki, Pezzini, Alessandro, Rolfs, Arndt, Giese, Anne-Katrin, Weir, David, Ross, Owen A, Lemmons, Robin, Soderholm, Martin, Cushman, Mary, Jood, Katarina, McDonough, Caitrin W, Bell, Steven, Linkohr, Birgit, Lee, Tsong-Hai, Putaala, Jukka, Anderson, Christopher D, Lopez, Oscar L, Jian, Xueqiu, Schminke, Ulf, Cullell, Natalia, Delgado, Pilar, Ibanez, Laura, Krupinski, Jerzy, Lioutas, Vasileios, Matsuda, Koichi, Montaner, Joan, Muino, Elena, Roquer, Jaume, Sarnowski, Chloe, Sattar, Naveed, Sibolt, Gerli, Teumer, Alexander, Rutten-Jacobs, Loes, Kanai, Masahiro, Gretarsdottir, Solveig, Rost, Natalia S, Yusuf, Salim, Almgren, Peter, Ay, Hakan, Bevan, Steve, Brown, Robert D, Carrera, Caty, Buring, Julie E, Chen, Wei-Min, Cotlarciuc, Ioana, de Bakker, Paul IW, DeStefano, Anita L, den Hoed, Marcel, Duan, Qing, Engelter, Stefan T, Falcone, Guido J, Gustafsson, Stefan, Hassan, Ahamad, Holliday, Elizabeth G, Howard, George, Hsu, Fang-Chi, Ingelsson, Erik, Harris, Tamara B, Kissela, Brett M, Kleindorfer, Dawn O, Langenberg, Claudia, Lemmens, Robin, Leys, Didier, Lin, Wei-Yu, Lorentzen, Erik, Magnusson, Patrik K, McArdle, Patrick F, Pulit, Sara L, Rice, Kenneth, Sakaue, Saori, Sapkota, Bishwa R, Tanislav, Christian, Thorleifsson, Gudmar, Thorsteinsdottir, Unnur, Tzourio, Christophe, van Duijn, Cornelia M, Walters, Matthew, Wareham, Nicholas J, Amin, Najaf, Aparicio, Hugo J, Attia, John, Beiser, Alexa S, Berr, Claudine, Bustamante, Mariana, Caso, Valeria, Choi, Seung Hoan, Chowhan, Ayesha, Dartigues, Jean-Francois, Delavaran, Hossein, Dorr, Marcus, Ford, Ian, Gurpreet, Wander S, Hamsten, Anders, Hozawa, Atsushi, Ingelsson, Martin, Iwasaki, Motoki, Kaffashian, Sara, Kalra, Lalit, Kjartansson, Olafur, Kloss, Manja, Labovitz, Daniel L, Laurie, Cathy C, Li, Linxin, Lind, Lars, Lindgren, Cecilia M, Makoto, Hirata, Minegishi, Naoko, Morris, Andrew P, Muller-Nurasyid, Martina, Norrving, Bo, Ogishima, Soichi, Parati, Eugenio A, Pedersen, Nancy L, Perola, Markus, Jousilahti, Pekka, Pileggi, Silvana, Rabionet, Raquel, Riba-Llena, Iolanda, Ribases, Marta, Romero, Jose R, Rudd, Anthony G, Sarin, Antti-Pekka, Sarju, Ralhan, Satoh, Mamoru, Sawada, Norie, Sigurdsson, Asgeir, Smith, Albert, Stine, O Colin, Stott, David J, Strauch, Konstantin, Takai, Takako, Tanaka, Hideo, Touze, Emmanuel, Tsugane, Shoichiro, Uitterlinden, Andre G, Valdimarsson, Einar M, van der Lee, Sven J, Wakai, Kenji, Williams, Stephen R, Wolfe, Charles DA, Wong, Quenna, Yamaji, Taiki, Sanghera, Dharambir K, Stefansson, Kari, Martinez-Majander, Nicolas, Sobue, Kenji, Soriano-Tarraga, Carolina, Volzke, Henry, Akpa, Onoja, Sarfo, Fred S, Akpalu, Albert, Obiako, Reginald, Wahab, Kolawole, Osaigbovo, Godwin, Owolabi, Lukman, Komolafe, Morenikeji, Jenkins, Carolyn, Arulogun, Oyedunni, Ogbole, Godwin, Adeoye, Abiodun M, Akinyemi, Joshua, Agunloye, Atinuke, Fakunle, Adekunle G, Uvere, Ezinne, Olalere, Abimbola, Adebajo, Olayinka J, Chen, Junshi, Clarke, Robert, Collins, Rory, Guo, Yu, Wang, Chen, Lv, Jun, Peto, Richard, Chen, Yiping, Fairhurst-Hunter, Zammy, Hill, Michael, Pozarickij, Alfred, Schmidt, Dan, Stevens, Becky, Turnbull, Iain, Yu, Canqing, Nagai, Akiko, Murakami, Yoishinori, Shiroma, Eric J, Sigurdsson, Sigurdur, Ghanbari, Mohsen, Boerwinkle, Eric, Fongang, Bernard, Wang, Ruiqi, Ikram, Mohammad K, Volker, Uwe, de Laat, Karlijn F, van Norden, Anouk GW, de Kort, Paul L, Vermeer, Sarah E, Brouwers, Paul JAM, Gons, Rob AR, den Heijer, Tom, van Dijk, Gert W, van Rooij, Frank GW, Aamodt, Anne H, Skogholt, Anne H, Willer, Cristen J, Heuch, Ingrid, Hagen, Knut, Fritsche, Lars G, Pedersen, Linda M, Ellekjaer, Hanne, Zhou, Wei, Martinsen, Amy E, Kristoffersen, Espen S, Thomas, Laurent F, Kleinschnitz, Christoph, Frantz, Stefan, Ungethum, Kathrin, Gallego-Fabrega, Cristina, Lledos, Miquel, Llucia-Carol, Laia, Sobrino, Tomas, Campos, Francisco, Castillo, Jose, Freijo, Marimar, Arenillas, Juan Francisco, Obach, Victor, Alvarez-Sabin, Jose, Molina, Carlos A, Ribo, Marc, Munoz-Narbona, Lucia, Lopez-Cancio, Elena, Millan, Monica, Diaz-Navarro, Rosa, Vives-Bauza, Cristofol, Serrano-Heras, Gemma, Segura, Tomas, Dhar, Rajat, Delgado-Mederos, Raquel, Prats-Sanchez, Luis, Camps-Renom, Pol, Blay, Natalia, Sumoy, Lauro, Marti-Fabregas, Joan, Schnohr, Peter, Jensen, Gorm B, Benn, Marianne, Afzal, Shoaib, Kamstrup, Pia R, van Setten, Jessica, van der Laan, Sander W, Vonk, Jet MJ, Kim, Bong-Jo, Curtze, Sami, Tiainen, Marjaana, Kinnunen, Janne, Menon, Vilas, Sung, Yun Ju, Yang, Chengran, Saillour-Glenisson, Florence, Gravel, Simon, Millwood, Iona Y, Gieger, Christian, Ninomiya, Toshiharu, Grabe, Hans J, Jukema, J Wouter, Rissanen, Ina L, Strbian, Daniel, Kim, Young Jin, Chen, Pei-Hsin, Mayerhofer, Ernst, Howson, Joanna MM, Adams, Hieab, Wassertheil-Smoller, Sylvia, Christensen, Kaare, Ikram, Mohammad A, Rundek, Tatjana, Worrall, Bradford B, Lathrop, G Mark, Riaz, Moeen, Simonsick, Eleanor M, Korv, Janika, Franca, Paulo HC, Zand, Ramin, Prasad, Kameshwar, Frikke-Schmidt, Ruth, Liman, Thomas, Haeusler, Karl Georg, Ruigrok, Ynte M, Heuschmann, Peter Ulrich, Longstreth, WT, Jung, Keum Ji, Bastarache, Lisa, Pare, Guillaume, Damrauer, Scott M, Chasman, Daniel I, Rotter, Jerome I, Zwart, John-Anker, Niiranen, Teemu J, Fornage, Myriam, Liaw, Yung-Po, Seshadri, Sudha, Fernandez-Cadenas, Israel, Walters, Robin G, Ruff, Christian T, Owolabi, Mayowa O, Huffman, Jennifer E, Milani, Lili, Kamatani, Yoichiro, Dichgans, Martin, Debette, Stephanie, Mishra, Aniket, Malik, Rainer, Hachiya, Tsuyoshi, Jurgenson, Tuuli, Namba, Shinichi, Posner, Daniel C, Kamanu, Frederick K, Koido, Masaru, Le Grand, Quentin, Shi, Mingyang, He, Yunye, Georgakis, Marios K, Caro, Ilana, Krebs, Kristi, Liaw, Yi-Ching, Vaura, Felix C, Lin, Kuang, Winsvold, Bendik Slagsvold, Srinivasasainagendra, Vinodh, Parodi, Livia, Bae, Hee-Joon, Chauhan, Ganesh, Chong, Michael R, Tomppo, Liisa, Akinyemi, Rufus, Roshchupkin, Gennady V, Habib, Naomi, Jee, Yon Ho, Thomassen, Jesper Qvist, Abedi, Vida, Carcel-Marquez, Jara, Nygaard, Marianne, Leonard, Hampton L, Yang, Chaojie, Yonova-Doing, Ekaterina, Knol, Maria J, Lewis, Adam J, Judy, Renae L, Ago, Tetsuro, Amouyel, Philippe, Armstrong, Nicole D, Bakker, Mark K, Bartz, Traci M, Bennett, David A, Bis, Joshua C, Bordes, Constance, Borte, Sigrid, Cain, Anael, Ridker, Paul M, Cho, Kelly, Chen, Zhengming, Cruchaga, Carlos, Cole, John W, de Jager, Phil L, de Cid, Rafael, Endres, Matthias, Ferreira, Leslie E, Geerlings, Mirjam I, Gasca, Natalie C, Gudnason, Vilmundur, Hata, Jun, He, Jing, Heath, Alicia K, Ho, Yuk-Lam, Havulinna, Aki S, Hopewell, Jemma C, Hyacinth, Hyacinth I, Inouye, Michael, Jacob, Mina A, Jeon, Christina E, Jern, Christina, Kamouchi, Masahiro, Keene, Keith L, Kitazono, Takanari, Kittner, Steven J, Konuma, Takahiro, Kumar, Amit, Lacaze, Paul, Launer, Lenore J, Lee, Keon-Joo, Lepik, Kaido, Li, Jiang, Li, Liming, Manichaikul, Ani, Markus, Hugh S, Marston, Nicholas A, Meitinger, Thomas, Mitchell, Braxton D, Montellano, Felipe A, Morisaki, Takayuki, Mosley, Thomas H, Nalls, Mike A, Nordestgaard, Borge G, O'Donnell, Martin J, Okada, Yukinori, Onland-Moret, N Charlotte, Ovbiagele, Bruce, Peters, Annette, Psaty, Bruce M, Rich, Stephen S, Rosand, Jonathan, Sabatine, Marc S, Sacco, Ralph L, Saleheen, Danish, Sandset, Else Charlotte, Salomaa, Veikko, Sargurupremraj, Muralidharan, Sasaki, Makoto, Satizabal, Claudia L, Schmidt, Carsten O, Shimizu, Atsushi, Smith, Nicholas L, Sloane, Kelly L, Sutoh, Yoichi, Sun, Yan V, Tanno, Kozo, Tiedt, Steffen, Tatlisumak, Turgut, Torres-Aguila, Nuria P, Tiwari, Hemant K, Tregouet, David-Alexandre, Trompet, Stella, Tuladhar, Anil Man, Tybjaerg-Hansen, Anne, van Vugt, Marion, Vibo, Riina, Verma, Shefali S, Wiggins, Kerri L, Wennberg, Patrik, Woo, Daniel, Wilson, Peter WF, Xu, Huichun, Yang, Qiong, Yoon, Kyungheon, Lee, Jin-Moo, Cheng, Yu-Ching, Meschia, James F, Chen, Wei Min, Sale, Michele M, Zonderman, Alan B, Evans, Michele K, Wilson, James G, Correa, Adolfo, Traylor, Matthew, Lewis, Cathryn M, Carty, Cara L, Reiner, Alexander, Haessler, Jeffrey, Langefeld, Carl D, Gottesman, Rebecca F, Yaffe, Kristine, Liu, Yong Mei, Kooperberg, Charles, Lange, Leslie A, Furie, Karen L, Arnett, Donna K, Benavente, Oscar R, Grewal, Raji P, Peddareddygari, Leema Reddy, Hveem, Kristian, Lindstrom, Sara, Wang, Lu, Smith, Erin N, Gordon, William, van Hylckama Vlieg, Astrid, de Andrade, Mariza, Brody, Jennifer A, Pattee, Jack W, Brumpton, Ben M, Suchon, Pierre, Chen, Ming-Huei, Frazer, Kelly A, Turman, Constance, Germain, Marine, MacDonald, James, Braekkan, Sigrid K, Armasu, Sebastian M, Pankratz, Nathan, Jackson, Rebecca D, Nielsen, Jonas B, Giulianini, Franco, Puurunen, Marja K, Ibrahim, Manal, Heckbert, Susan R, Bammler, Theo K, McCauley, Bryan M, Taylor, Kent D, Pankow, James S, Reiner, Alexander P, Gabrielsen, Maiken E, Deleuze, Jean-Francois, O'Donnell, Chris J, Kim, Jihye, McKnight, Barbara, Kraft, Peter, Hansen, John-Bjarne, Rosendaal, Frits R, Heit, John A, Tang, Weihong, Morange, Pierre-Emmanuel, Johnson, Andrew D, Kabrhel, Christopher, van Dijk, Ewoud J, Koudstaal, Peter J, Luijckx, Gert-Jan, Nederkoorn, Paul J, van Oostenbrugge, Robert J, Visser, Marieke C, Wermer, Marieke JH, Kappelle, L Jaap, Esko, Tonu, Metspalu, Andres, Magi, Reedik, Nelis, Mari, Irvin, Marguerite R, de Leeuw, Frank-Erik, Levi, Christopher R, Maguire, Jane, Jimenez-Conde, Jordi, Sharma, Pankaj, Sudlow, Cathie LM, Rannikmae, Kristiina, Schmidt, Reinhold, Slowik, Agnieszka, Pera, Joanna, Thijs, Vincent NS, Lindgren, Arne G, Ilinca, Andreea, Melander, Olle, Engstrom, Gunnar, Rexrode, Kathryn M, Rothwell, Peter M, Stanne, Tara M, Johnson, Julie A, Danesh, John, Butterworth, Adam S, Heitsch, Laura, Boncoraglio, Giorgio B, Kubo, Michiaki, Pezzini, Alessandro, Rolfs, Arndt, Giese, Anne-Katrin, Weir, David, Ross, Owen A, Lemmons, Robin, Soderholm, Martin, Cushman, Mary, Jood, Katarina, McDonough, Caitrin W, Bell, Steven, Linkohr, Birgit, Lee, Tsong-Hai, Putaala, Jukka, Anderson, Christopher D, Lopez, Oscar L, Jian, Xueqiu, Schminke, Ulf, Cullell, Natalia, Delgado, Pilar, Ibanez, Laura, Krupinski, Jerzy, Lioutas, Vasileios, Matsuda, Koichi, Montaner, Joan, Muino, Elena, Roquer, Jaume, Sarnowski, Chloe, Sattar, Naveed, Sibolt, Gerli, Teumer, Alexander, Rutten-Jacobs, Loes, Kanai, Masahiro, Gretarsdottir, Solveig, Rost, Natalia S, Yusuf, Salim, Almgren, Peter, Ay, Hakan, Bevan, Steve, Brown, Robert D, Carrera, Caty, Buring, Julie E, Chen, Wei-Min, Cotlarciuc, Ioana, de Bakker, Paul IW, DeStefano, Anita L, den Hoed, Marcel, Duan, Qing, Engelter, Stefan T, Falcone, Guido J, Gustafsson, Stefan, Hassan, Ahamad, Holliday, Elizabeth G, Howard, George, Hsu, Fang-Chi, Ingelsson, Erik, Harris, Tamara B, Kissela, Brett M, Kleindorfer, Dawn O, Langenberg, Claudia, Lemmens, Robin, Leys, Didier, Lin, Wei-Yu, Lorentzen, Erik, Magnusson, Patrik K, McArdle, Patrick F, Pulit, Sara L, Rice, Kenneth, Sakaue, Saori, Sapkota, Bishwa R, Tanislav, Christian, Thorleifsson, Gudmar, Thorsteinsdottir, Unnur, Tzourio, Christophe, van Duijn, Cornelia M, Walters, Matthew, Wareham, Nicholas J, Amin, Najaf, Aparicio, Hugo J, Attia, John, Beiser, Alexa S, Berr, Claudine, Bustamante, Mariana, Caso, Valeria, Choi, Seung Hoan, Chowhan, Ayesha, Dartigues, Jean-Francois, Delavaran, Hossein, Dorr, Marcus, Ford, Ian, Gurpreet, Wander S, Hamsten, Anders, Hozawa, Atsushi, Ingelsson, Martin, Iwasaki, Motoki, Kaffashian, Sara, Kalra, Lalit, Kjartansson, Olafur, Kloss, Manja, Labovitz, Daniel L, Laurie, Cathy C, Li, Linxin, Lind, Lars, Lindgren, Cecilia M, Makoto, Hirata, Minegishi, Naoko, Morris, Andrew P, Muller-Nurasyid, Martina, Norrving, Bo, Ogishima, Soichi, Parati, Eugenio A, Pedersen, Nancy L, Perola, Markus, Jousilahti, Pekka, Pileggi, Silvana, Rabionet, Raquel, Riba-Llena, Iolanda, Ribases, Marta, Romero, Jose R, Rudd, Anthony G, Sarin, Antti-Pekka, Sarju, Ralhan, Satoh, Mamoru, Sawada, Norie, Sigurdsson, Asgeir, Smith, Albert, Stine, O Colin, Stott, David J, Strauch, Konstantin, Takai, Takako, Tanaka, Hideo, Touze, Emmanuel, Tsugane, Shoichiro, Uitterlinden, Andre G, Valdimarsson, Einar M, van der Lee, Sven J, Wakai, Kenji, Williams, Stephen R, Wolfe, Charles DA, Wong, Quenna, Yamaji, Taiki, Sanghera, Dharambir K, Stefansson, Kari, Martinez-Majander, Nicolas, Sobue, Kenji, Soriano-Tarraga, Carolina, Volzke, Henry, Akpa, Onoja, Sarfo, Fred S, Akpalu, Albert, Obiako, Reginald, Wahab, Kolawole, Osaigbovo, Godwin, Owolabi, Lukman, Komolafe, Morenikeji, Jenkins, Carolyn, Arulogun, Oyedunni, Ogbole, Godwin, Adeoye, Abiodun M, Akinyemi, Joshua, Agunloye, Atinuke, Fakunle, Adekunle G, Uvere, Ezinne, Olalere, Abimbola, Adebajo, Olayinka J, Chen, Junshi, Clarke, Robert, Collins, Rory, Guo, Yu, Wang, Chen, Lv, Jun, Peto, Richard, Chen, Yiping, Fairhurst-Hunter, Zammy, Hill, Michael, Pozarickij, Alfred, Schmidt, Dan, Stevens, Becky, Turnbull, Iain, Yu, Canqing, Nagai, Akiko, Murakami, Yoishinori, Shiroma, Eric J, Sigurdsson, Sigurdur, Ghanbari, Mohsen, Boerwinkle, Eric, Fongang, Bernard, Wang, Ruiqi, Ikram, Mohammad K, Volker, Uwe, de Laat, Karlijn F, van Norden, Anouk GW, de Kort, Paul L, Vermeer, Sarah E, Brouwers, Paul JAM, Gons, Rob AR, den Heijer, Tom, van Dijk, Gert W, van Rooij, Frank GW, Aamodt, Anne H, Skogholt, Anne H, Willer, Cristen J, Heuch, Ingrid, Hagen, Knut, Fritsche, Lars G, Pedersen, Linda M, Ellekjaer, Hanne, Zhou, Wei, Martinsen, Amy E, Kristoffersen, Espen S, Thomas, Laurent F, Kleinschnitz, Christoph, Frantz, Stefan, Ungethum, Kathrin, Gallego-Fabrega, Cristina, Lledos, Miquel, Llucia-Carol, Laia, Sobrino, Tomas, Campos, Francisco, Castillo, Jose, Freijo, Marimar, Arenillas, Juan Francisco, Obach, Victor, Alvarez-Sabin, Jose, Molina, Carlos A, Ribo, Marc, Munoz-Narbona, Lucia, Lopez-Cancio, Elena, Millan, Monica, Diaz-Navarro, Rosa, Vives-Bauza, Cristofol, Serrano-Heras, Gemma, Segura, Tomas, Dhar, Rajat, Delgado-Mederos, Raquel, Prats-Sanchez, Luis, Camps-Renom, Pol, Blay, Natalia, Sumoy, Lauro, Marti-Fabregas, Joan, Schnohr, Peter, Jensen, Gorm B, Benn, Marianne, Afzal, Shoaib, Kamstrup, Pia R, van Setten, Jessica, van der Laan, Sander W, Vonk, Jet MJ, Kim, Bong-Jo, Curtze, Sami, Tiainen, Marjaana, Kinnunen, Janne, Menon, Vilas, Sung, Yun Ju, Yang, Chengran, Saillour-Glenisson, Florence, Gravel, Simon, Millwood, Iona Y, Gieger, Christian, Ninomiya, Toshiharu, Grabe, Hans J, Jukema, J Wouter, Rissanen, Ina L, Strbian, Daniel, Kim, Young Jin, Chen, Pei-Hsin, Mayerhofer, Ernst, Howson, Joanna MM, Adams, Hieab, Wassertheil-Smoller, Sylvia, Christensen, Kaare, Ikram, Mohammad A, Rundek, Tatjana, Worrall, Bradford B, Lathrop, G Mark, Riaz, Moeen, Simonsick, Eleanor M, Korv, Janika, Franca, Paulo HC, Zand, Ramin, Prasad, Kameshwar, Frikke-Schmidt, Ruth, Liman, Thomas, Haeusler, Karl Georg, Ruigrok, Ynte M, Heuschmann, Peter Ulrich, Longstreth, WT, Jung, Keum Ji, Bastarache, Lisa, Pare, Guillaume, Damrauer, Scott M, Chasman, Daniel I, Rotter, Jerome I, Zwart, John-Anker, Niiranen, Teemu J, Fornage, Myriam, Liaw, Yung-Po, Seshadri, Sudha, Fernandez-Cadenas, Israel, Walters, Robin G, Ruff, Christian T, Owolabi, Mayowa O, Huffman, Jennifer E, Milani, Lili, Kamatani, Yoichiro, Dichgans, Martin, and Debette, Stephanie

Abstract

Previous genome-wide association studies (GWASs) of stroke — the second leading cause of death worldwide — were conducted predominantly in populations of European ancestry1,2. Here, in cross-ancestry GWAS meta-analyses of 110,182 patients who have had a stroke (five ancestries, 33% non-European) and 1,503,898 control individuals, we identify association signals for stroke and its subtypes at 89 (61 new) independent loci: 60 in primary inverse-variance-weighted analyses and 29 in secondary meta-regression and multitrait analyses. On the basis of internal cross-ancestry validation and an independent follow-up in 89,084 additional cases of stroke (30% non-European) and 1,013,843 control individuals, 87% of the primary stroke risk loci and 60% of the secondary stroke risk loci were replicated (P < 0.05). Effect sizes were highly correlated across ancestries. Cross-ancestry fine-mapping, in silico mutagenesis analysis3, and transcriptome-wide and proteome-wide association analyses revealed putative causal genes (such as SH3PXD2A and FURIN) and variants (such as at GRK5 and NOS3). Using a three-pronged approach4, we provide genetic evidence for putative drug effects, highlighting F11, KLKB1, PROC, GP1BA, LAMC2 and VCAM1 as possible targets, with drugs already under investigation for stroke for F11 and PROC. A polygenic score integrating cross-ancestry and ancestry-specific stroke GWASs with vascular-risk factor GWASs (integrative polygenic scores) strongly predicted ischaemic stroke in populations of European, East Asian and African ancestry5. Stroke genetic risk scores were predictive of ischaemic stroke independent of clinical risk factors in 52,600 clinical-trial participants with cardiometabolic disease. Our results provide insights to inform biology, reveal potential drug targets and derive genetic risk prediction tools across ancestries.

Published
2022

19. Dietary patterns associated with stroke among West Africans: A case–control study

Author

Okekunle, Akinkunmi P, primary, Asowata, Osahon, additional, Akpa, Onoja M, additional, Ovbiagele, Bruce, additional, Fakunle, Adekunle, additional, Komolafe, Morenikeji, additional, Arulogun, Oyedunni, additional, Sarfo, Fred S, additional, Akpalu, Albert, additional, Obiako, Reginald, additional, Wahab, Kolawole, additional, Osaigbovo, Godwin, additional, Owolabi, Lukman, additional, Ogbole, Godwin, additional, Akinyemi, Joshua, additional, Adeniyi, Sunday, additional, Calys-Tagoe, Benedict, additional, Aridegbe, Mayowa, additional, Adebowale, Akintunde, additional, Dambatta, Hamisu, additional, Agunloye, Atinuke, additional, Oyinloye, Olalekan, additional, Aderibigbe, Adeniyi, additional, Suleiman, Isah, additional, Adeoye, Abiodun M, additional, Akpalu, Josephine, additional, Agbogu-Ike, Obiageli, additional, Tiwari, Hemant K, additional, Arnett, Donna, additional, Akinyemi, Rufus, additional, and Owolabi, Mayowa O, additional

Published
2022
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20. Patient- and Health Facility-Level Determinants of Stroke Fatality Across 15 Large Hospitals in Ghana & Nigeria

Author

Sarfo, Fred S., primary, Onoja, Akpa, additional, Ovbiagele, Bruce, additional, Akpalu, Albert, additional, Wahab, Kolawole, additional, Obiako, Reginald, additional, Morenikeji, Komolafe, additional, Owolabi, Lukman, additional, Ogbole, Godwin, additional, Calys-Tagoe, Benedict, additional, Uvere, Ezinne, additional, Sanni, Taofeek, additional, Gebregziabher, Mulugeta, additional, Salaam, Abdul, additional, Akintunde, Adeseye A., additional, olowookere, samuel, additional, Ibinaiye, Phillip, additional, Akinyemi, Joshua, additional, Uwanuruochi, Kelechukwu, additional, Olayemi, Balogun, additional, Odunlami, Olufemi A., additional, Abunimye, Esther, additional, Arulogun, Oyedunni, additional, Isah, Sulaiman Y., additional, Abubakar, Sani A., additional, Adebayo, Oladimeji, additional, Adebayo, Phillip, additional, Shidali, Vincent, additional, Chukwuonye, Innocent I., additional, Akpalu, Josephine, additional, Fakunle, Adekunle, additional, Asowata, Osahon J., additional, Sanya, Emmanuel O., additional, Amusa, Ganiyu, additional, Onyeonoro, Ugochukwu Uchenna, additional, Ogunmodede, James A., additional, Sule, Abdullaleef G., additional, Akinsanya, Cynthia, additional, Mensah, Yaw, additional, Oyinloye, Olalekan I., additional, Appiah, Lambert, additional, Agunloye, Atinuke M., additional, Osaigbovo, Godwin O., additional, Olabinri, Eunice, additional, Kolo, Phillip M., additional, Okeke, Obiora, additional, Adeoye, Abiodun M., additional, Ajose, Olabamiji, additional, Jenkins, Carolyn, additional, Lackland, Daniel T., additional, Egberongbe, Adedeji A., additional, Adeniji, Olaleye, additional, Adeleye, Osinmhiaherhuo Ohifemen, additional, Tiwari, Hermant K., additional, Laryea, Ruth Y., additional, Olunuga, Taiwo, additional, Akinwande, Kazeem S., additional, Imoh, Lucius, additional, Ogah, Okechukwu S., additional, Melikam, Ezinne, additional, Adebolaji, Adeyemo, additional, Oguike, Wisdom, additional, Ogunronbi, Mayowa, additional, Adeniyi, Wasiu, additional, Olugbo, Obiabo Y., additional, Bello, Abiodun H., additional, Ohagwu, Kenneth A., additional, Ogunjimi, Luqman, additional, Agyekum, Francis, additional, Iheonye, Henry, additional, Adesina, Julius, additional, Diala, Samuel, additional, Dambatta, Hamisu A., additional, Ikubor, Joyce, additional, Singh, Arti, additional, Adamu, Sheila, additional, Obese, Vida, additional, Adesie, Nathaniel, additional, Owusu, Dorcas, additional, Ampofo, Michael, additional, Tagge, Raelle, additional, Efidi, Richard, additional, Fawale, Bimbo, additional, Yaria, Joseph O., additional, Akinyemi, Rufus, additional, OWOLABI, Mayowa, additional, and Study, SIREN, additional

Published
2022
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21. Characteristics, complications, and gaps in evidence-based interventions in rheumatic heart disease: the Global Rheumatic Heart Disease Registry (the REMEDY study)

Author

Zühlke, Liesl, Engel, Mark E., Karthikeyan, Ganesan, Rangarajan, Sumathy, Mackie, Pam, Cupido, Blanche, Mauff, Katya, Islam, Shofiqul, Joachim, Alexia, Daniels, Rezeen, Francis, Veronica, Ogendo, Stephen, Gitura, Bernard, Mondo, Charles, Okello, Emmy, Lwabi, Peter, Al-Kebsi, Mohammed M., Hugo-Hamman, Christopher, Sheta, Sahar S., Haileamlak, Abraham, Daniel, Wandimu, Goshu, Dejuma Y., Abdissa, Senbeta G., Desta, Araya G., Shasho, Bekele A., Begna, Dufera M., ElSayed, Ahmed, Ibrahim, Ahmed S., Musuku, John, Bode-Thomas, Fidelia, Okeahialam, Basil N., Ige, Olukemi, Sutton, Christopher, Misra, Rajeev, Abul Fadl, Azza, Kennedy, Neil, Damasceno, Albertino, Sani, Mahmoud, Ogah, Okechukwu S., Olunuga, Taiwo, Elhassan, Huda H.M., Mocumbi, Ana Olga, Adeoye, Abiodun M., Mntla, Phindile, Ojji, Dike, Mucumbitsi, Joseph, Teo, Koon, Yusuf, Salim, and Mayosi, Bongani M.

Published
2015
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22. Day and Night Blood Pressure Variability among Older Persons in South-Western Nigeria.

Author

Adeoye, Abiodun M., Adebusoye, Lawrence Adekunle, Fakunle, Adekunle G., Aderonmu, Olajumoke I., Adebayo, Oladimeji M., Michael, Obaro S., Adetona, Moses Olusola, Thrift, Amanda G., Olaiya, Muideen T., and Owolabi, Mayowa O.

Subjects
BLOOD pressure, OLDER people, HYPERTENSION, PUBLIC health
Abstract

Background: Hypertension is the largest contributor to the global burden of disease. Emerging risk factors for cardiovascular disease include blood pressure variability (BPV), but evidence on BPV is lacking among older Nigerians. We reported BPV in a cohort of older persons at the University College Hospital (UCH), Ibadan. Methods: We conducted a retrospective cohort study of respondents aged >50 years within the Ibadan Ambulatory Blood Pressure Registry at the UCH, Ibadan, Nigeria. Socio-demographic characteristics, lifestyle habits and anthropometric measurements were obtained. Results: Among 639 respondents, 332 (52.0%) were female. The blood pressure (BP) variables were strongly associated with age. Compared with younger age groups, mean diastolic BP (DBP) was less at an older age, whereas mean pulse pressure was greater. During the wake-up and sleep periods, mean DBP and mean arterial BP were less with each increasing age category, whereas mean pulse pressure was larger with each increasing age category. BP dipping, systolic, diastolic and mean arterial BP decreased with age. Overall, timed BPV increased significantly with increasing age. The prevalence of white-coat hypertension was greater among older participants than younger participants. Most respondents in the 50-59 years' age group were non-dippers (55.8%), whereas 33.7% of older respondents were reverse-dippers. Conclusion: Older persons experienced a greater abnormal circadian blood variation and greater BPV than younger people. In Nigeria, follow-up data are needed to determine the prognostic significance of these data in this population. [ABSTRACT FROM AUTHOR]

Published
2022
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23. BASELINE CLINICAL PROFILE OF CHRONIC HEART FAILURE IN NIGERIA: RESULT OF A NATIONAL REGISTRY

Author

Ogah, Okechukwu Samuel, primary, Saidu, Hadiza, additional, Karaye, Kamilu, additional, Adebayo, Rasaq, additional, Mbakwem, Amam, additional, Adamu, Umar Gati, additional, Adebayo, Saheed O., additional, Adeoye, Abiodun M., additional, Aje, Akinyemi, additional, Adebiyi, Adewole A., additional, Sogade, Taiwo, additional, and Sani, Mahmoud, additional

Published
2021
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25. Risk Factor Characterization of Ischemic Stroke Subtypes Among West Africans

Author

Sarfo, Fred S., Ovbiagele, Bruce, Akpa, Onoja, Akpalu, Albert, Wahab, Kolawole, Obiako, Reginald, Komolafe, Morenikeji, Owolabi, Lukman, Ogbole, Godwin, Calys-Tagoe, Benedict, Fakunle, Adekunle, Sanni, Taofeek, Mulugeta, Gebregziabher, Abdul, Salaam, Akintunde, Adeseye A., Olowookere, Samuel, Uvere, Ezinne O., Ibinaiye, Philip, Akinyemi, Joshua, Uwanuruochi, Kelechukwu, Olayemi, Balogun, Odunlami, Olufemi A., Abunimye, Esther, Arulogun, Oyedunni, Isah, Suleiman Y., Abubakar, Sani A., Oladimeji, Adebayo, Adebayo, Philip, Shidali, Vincent, Chukwuonye, Innocent I., Akpalu, Josephine, Tito-Ilori, Moyinoluwalogo M., Asowata, Osahon J., Sanya, Emmanuel O., Amusa, Ganiyu, Onyeonoro, Ugochukwu, Ogunmodede, James A., Sule, Abdullateef G., Akisanya, Cynthia, Mensah, Yaw, Oyinloye, Olalekan I., Appiah, Lambert, Agunloye, Atinuke M., Osaigbovo, Godwin O., Olabinri, Eunice, Kolo, Philip M., Okeke, Obiora, Adeoye, Abiodun M., Ajose, Olabamiji, Jenkins, Carolyn, Lackland, Daniel T., Egberongbe, Adedeji A., Adeniji, Olaleye, Ohifemen Adeleye, Osimhiarherhuo, Tiwari, Hemant K., Arnett, Donna, Laryea, Ruth Y., Olunuga, Taiwo, Akinwande, Kazeem S., Imoh, Lucius, Ogah, Okechukwu S., Melikam, Ezinne S., Adebolaji, Adeyemo, Oguike, Wisdom, Ogunronbi, Olumayowa, Adeniyi, Wasiu, Olugbo, Obiabo Y., Bello, Abiodun H., Ohagwu, Kenneth A., Ogunjimi, Luqman, Agyekum, Francis, Iheonye, Henry, Adesina, Julius, Diala, Samuel, Dambatta, Hamisu A., Ikubor, Joyce, Singh, Arti, Adamu, Sheila, Obese, Vida, Adusei, Nathaniel, Owusu, Dorcas, Ampofo, Michael, Tagge, Raelle, Efidi, Richard, Fawale, Bimbo, Yaria, Joseph, Akinyemi, Rufus, and Owolabi, Mayowa

Abstract

Supplemental Digital Content is available in the text.

Published
2022
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27. Echocardiographic Abnormalities and Determinants of 1‐Month Outcome of Stroke Among West Africans in the SIREN Study

Author

Adeoye, Abiodun M., primary, Ovbiagele, Bruce, additional, Akinyemi, Joshua O., additional, Ogah, Okechukwu S., additional, Akinyemi, Rufus, additional, Gebregziabher, Mulugeta, additional, Wahab, Kolawole, additional, Fakunle, Adekunle G., additional, Akintunde, Adeseye, additional, Adebayo, Oladimeji, additional, Aje, Akinyemi, additional, Tiwari, Hemant K., additional, Arnett, Donna, additional, Agyekum, Francis, additional, Appiah, Lambert T., additional, Amusa, Ganiyu, additional, Olunuga, Taiwo O., additional, Onoja, Akpa, additional, Sarfo, Fred S., additional, Akpalu, Albert, additional, Jenkins, Carolyn, additional, Lackland, Daniel, additional, Owolabi, Lukman, additional, Komolafe, Morenikeji, additional, Faniyan, Moyinoluwalogo M., additional, Arulogun, Oyedunni, additional, Obiako, Reginald, additional, and Owolabi, Mayowa, additional

Published
2019
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28. The burden of stroke in Africa: a glance at the present and a glimpse into the future

Author

Owolabi, Mayowa O, Arulogun, Oyedunni, Melikam, Sylvia, Adeoye, Abiodun M, Akarolo-Anthony, Sally, Akinyemi, Rufus, Arnett, Donna, Tiwari, Hemant, Gebregziabher, Mulugeta, Jenkins, Carolyn, Lackland, Daniel, Ovbiagele, Bruce, Akpalu, Albert, Sagoe, Kwamena, Stephen Sarfo, Fred, Obiako, Reginald, and Owolabi, Lukman

Subjects
Cost of Illness, Cardiovascular Topics, Incidence, Africa, prevalence, Age Factors, Humans, epidemiology, Quality-Adjusted Life Years, Global Health, stroke, mortality
Abstract

Summary Objective Information on the current burden of stroke in Africa is limited. The aim of this review was to comprehensively examine the current and projected burden of stroke in Africa. Methods We systematically reviewed the available literature (PubMed and AJOL) from January 1960 and June 2014 on stroke in Africa. Percentage change in age-adjusted stroke incidence, mortality and disability-adjusted life years (DALYs) for African countries between 1990 and 2010 were calculated from the Global Burden of Diseases (GBD) model-derived figures. Results Community-based studies revealed an age-standardised annual stroke incidence rate of up to 316 per 100 000 population, and age-standardised prevalence rates of up to 981 per 100 000. Model-based estimates showed significant mean increases in age-standardised stroke incidence. The peculiar factors responsible for the substantial disparities in incidence velocity, ischaemic stroke proportion, mean age and case fatality compared to high-income countries remain unknown. Conclusions While the available study data and evidence are limited, the burden of stroke in Africa appears to be increasing.

Published
2015

29. Clinical Outcomes in 3343 Children and Adults with Rheumatic Heart Disease from 14 Low and Middle Income Countries: 2-Year Follow-up of the Global Rheumatic Heart Disease Registry (the REMEDY study)

Author

Zühlke, Liesl, Karthikeyan, Ganesan, Engel, Mark E, Rangarajan, Sumathy, Mackie, Pam, Cupido, Blanche, Mauff, Katya, Islam, Shofiqul, Daniels, Rezeen, Francis, Veronica, Ogendo, Stephen, Gitura, Bernard, Mondo, Charles, Okello, Emmy, Lwabi, Peter, Al-Kebsi, Mohammed M, Hugo-Hamman, Christopher, Sheta, Sahar S, Haileamlak, Abraham, Daniel, Wandimu, Goshu, Dejuma Yadeta, Abdissa, Senbeta G, Desta, Araya G, Shasho, Bekele A, Begna, Dufera M, ElSayed, Ahmed, Ibrahim, Ahmed S, Musuku, John, Bode-Thomas, Fidelia, Yilgwan, Christopher C, Amusa, Ganiyu A, Ige, Olukemi, Okeahialam, Basil, Sutton, Christopher, Misra, Rajeev, Abul Fadl, Azza, Kennedy, Neil, Damasceno, Albertino, Sani, Mahmoud U, Ogah, Okechukwu S, Olunuga, Taiwo, ElHassan, Huda, Mocumbi, Ana Olga, Adeoye, Abiodun M, Mntla, Pindile S, Ojji, Dike B, Mucumbitsi, Joseph, Teo, Koon, Yusuf, Salim, and Mayosi, Bongani M

Abstract

BACKGROUND: -There are few contemporary data on the mortality and morbidity associated with rheumatic heart disease (RHD) or information on their predictors. We report the two year follow-up of individuals with RHD from 14 low and middle income countries in Africa and Asia.METHODS: -Between January 2010 and November 2012, we enrolled 3343 patients from 25 centers in 14 countries and followed them for two years to assess mortality, congestive heart failure (CHF), stroke or transient ischemic attack (TIA), recurrent acute rheumatic fever (ARF), and infective endocarditis (IE).RESULTS: -Vital status at 24 months was known for 2960 (88.5%) patients. Two thirds were female. Although patients were young (median age 28 years, interquartile range 18 to 40), the two year case fatality rate was high (500 deaths, 16.9%). Mortality rate was 116.3/1000 patient-years in the first year and 65.4/1000 patient-years in the second year. Median age at death was 28.7 years. Independent predictors of death were severe valve disease (hazard ratio (HR) 2.36, 95% confidence interval (CI) 1.80-3.11), CHF (HR 2.16, 95% CI 1.70-2.72), New York Heart Association functional class III/IV (HR 1.67, 95% CI 1.32-2.10), atrial fibrillation (AF) (HR 1.40, 95% CI 1.10-1.78) and older age (HR 1.02, 95% CI 1.01-1.02 per year increase) at enrolment. Post-primary education (HR 0.67, 95% CI 0.54-0.85) and female sex (HR 0.65, 95%CI 0.52-0.80) were associated with lower risk of death. 204 (6.9%) had new CHF (incidence, 38.42/1000 patient-years), 46 (1.6%) had a stroke or TIA (8.45/1000 patient-years), 19 (0.6%) had ARF (3.49/1000 patient-years), and 20 (0.7%) had IE (3.65/1000 patient-years). Previous stroke and older age were independent predictors of stroke/TIA or systemic embolism. Patients from low and lower-middle income countries had significantly higher age- and sex-adjusted mortality compared to patients from upper-middle income countries. Valve surgery was significantly more common in upper-middle income than in lower-middle- or low-income countries.CONCLUSIONS: -Patients with clinical RHD have high mortality and morbidity despite being young; those from low and lower-middle income countries had a poorer prognosis associated with advanced disease and low education. Programs focused on early detection and treatment of clinical RHD are required to improve outcomes.

Published
2016

30. Correction to: African Control of Hypertension through Innovative Epidemiology and a Vibrant Ecosystem (ACHIEVE): novel strategies for accelerating hypertension control in Africa

Author

Owolabi, Mayowa, Olowoyo, Paul, Mocumbi, Ana, Ogah, Okechukwu S., Odili, Augustine, Wahab, Kolawole, Ojji, Dike, Adeoye, Abiodun M., Akinyemi, Rufus, Akpalu, Albert, Obiako, Reginald, Sarfo, Fred S., Bavuma, Charlotte, Beheiry, Hind Mamoun, Ibrahim, Moshen, El Aroussy, Wafaa, Parati, Gianfranco, Dzudie, Anastase, Singh, Sandhya, Akpa, Onoja, Kengne, Andre Pascal, Okekunle, Akinkunmi Paul, de Graft Aikins, Ama, Agyemang, Charles, Ogedegbe, Gbenga, Ovbiagele, Bruce, Garg, Renu, Campbell, Norman R. C., Lackland, Daniel T., Barango, Prebo, Slama, Slim, Varghese, Cherian V., Whelton, Paul K., and Zhang, Xin-Hua

Published
2024
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31. Development and Validation of a Electrocardiographic Diagnostic Score of Heart Failure Among Patients with Hypertension Attending a Tertiary Hospital in Ibadan, Nigeria: The RISK-HHF Case-Control Study.

Author

Oguntade, Ayodipupo S., Ajayi, IkeOluwapo O., Aje, Akinyemi, Adebiyi, Adewole A., Ogah, Okechukwu S., and Adeoye, Abiodun M.

Abstract

Objectives: Hypertension is the leading cause of HF in sub-Saharan Africa. Electrocardiography (ECG) is a cheap and easily available stratification tool for the diagnosis and prognostication of individuals with hypertension. The aim of this study was to develop an ECG-based HF diagnostic score among patients with hypertension attending a specialist cardiology clinic. Methods: One hundred and one (101) case-control age- and sex-matched pairs were recruited. The study population were adults with a clinical diagnosis of hypertensive HF failure (cases) and systemic hypertension without HF (controls). Participants underwent clinical assessment and ECG. Associations between ECG variables and HF risk were tested with chi square test. Logistic regression modelling (age- and sex adjusted) was trained on a random subset of participants and tested on the remaining participants to determine the ECG abnormalities that are diagnostic of HF and develop a HF diagnostic score. The HF diagnostic score was then validated in an independent dataset of the ECG-Hypertension Audit. Goodness of fit and c-statistics of the HF summed diagnostic score in the training, testing and validation datasets are presented. A two-sided p value of <0.05 was considered statistically significant. Results: The independent ECG diagnostic markers of HF among hypertensive patients in this study in decreasing order of effect size were sinus tachycardia (aOR: 7.72, 95% CI: 2.31-25.85). arrhythmia (aOR: 7.14, 95% CI: 2.57-19.86), left ventricular hypertrophy (aOR: 4.47; 1.85-10.77) and conduction abnormality (aOR: 3.41, 95% CI: 1.21-9.65). The HF summed diagnostic score showed excellent calibration and discrimination in the training (Hosmer Lemeshow p=0.90; c-statistic 0.82; 95% CI 0.76e0.89) and test samples (Hosmer Lemeshow p=0.31; c-statistic 0.73 95% CI 0.60 to 0.87) of the derivation cohort and an independent validation audit cohort (Hosmer Lemeshow p=0.17; c-statistic 0.79 95% CI 0.74 to 0.84) respectively. The model showed high diagnostic accuracy in individuals with different intermediate pre-test probabilities of HF. Conclusions: A ECG based HF score consisting of sinus tachycardia, arrhythmia, conduction abnormality and left ventricular hypertrophy is diagnostic of HF especially in those with intermediate pre-test probability of HF. This has clinical importance in the stratification of individuals with systemic hypertension. [ABSTRACT FROM AUTHOR]

Published
2020
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32. Knowledge, attitudes and practices of West Africans on genetic studies of stroke: Evidence from the SIREN Study

Author

Akinyemi, Rufus O, primary, Sarfo, Fred S, additional, Akinyemi, Joshua, additional, Singh, Arti, additional, Onoja Akpa, Matthew, additional, Akpalu, Albert, additional, Owolabi, Lukman, additional, Adeoye, Abiodun M., additional, Obiako, Reginald, additional, Wahab, Kolawole, additional, Sanya, Emmanuel, additional, Komolafe, Morenikeji, additional, Ogbole, Godwin, additional, Fawale, Michael, additional, Adebayo, Philip, additional, Osaigbovo, Godwin, additional, Sunmonu, Taofiki, additional, Olowoyo, Paul, additional, Chukwuonye, Innocent, additional, Obiabo, Yahaya, additional, Adeniji, Olaleye, additional, Fakunle, Gregory, additional, Melikam, Ezinne, additional, Saulson, Raelle, additional, Yaria, Joseph, additional, Uwanruochi, Kelechi, additional, Ibinaiye, Phillip, additional, Amusa, Ganiyu Adeniyi, additional, Yahaya, Isah Suleiman, additional, Dambatta, Abdullahi Hamisu, additional, Faniyan, Mercy, additional, Olowoniyi, Peter, additional, Bock-Oruma, Andrew, additional, Joseph, Odo Chidi, additional, Oguntade, Ayodipupo, additional, Kolo, Philip, additional, Laryea, Ruth, additional, Lakoh, Sulaiman, additional, Uvere, Ezinne, additional, Farombi, Temitope, additional, Akpalu, Josephine, additional, Oyinloye, Olalekan, additional, Appiah, Lambert, additional, Calys-Tagoe, Benedict, additional, Shidali, Vincent, additional, Tabari, Nasir Abdulkadir, additional, Adebayo, Oladimeji, additional, Efidi, Richard, additional, Adeleye, Osi, additional, Owusu, Dorcas, additional, Ogunjimi, Luqman, additional, Aridegbe, Olumayowa, additional, Imoh, Chidiebere Lucius, additional, Sanni, Taofeeq, additional, Gebreziabher, Mulugeta, additional, Hemant, Tiwari, additional, Arulogun, Oyedunni, additional, Ogunniyi, Adesola, additional, Jenkins, Carolyn, additional, Owolabi, Mayowa, additional, and Ovbiagele, Bruce, additional

Published
2018
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34. Prevalence and Prognostic Features of ECG Abnormalities in Acute Stroke: Findings From the SIREN Study Among Africans

Author

Adeoye, Abiodun M., primary, Ogah, Okechukwu S., additional, Ovbiagele, Bruce, additional, Akinyemi, Rufus, additional, Shidali, Vincent, additional, Agyekum, Francis, additional, Aje, Akinyemi, additional, Adebayo, Oladimeji, additional, Akinyemi, Joshua O., additional, Kolo, Philip, additional, Appiah, Lambert Tetteh, additional, Iheonye, Henry, additional, Kelechukwu, Uwanuruochi, additional, Ganiyu, Amusa, additional, Olunuga, Taiwo O., additional, Akpa, Onoja, additional, Olagoke, Ojo Olakanmi, additional, Sarfo, Fred Stephen, additional, Wahab, Kolawole, additional, Olowookere, Samuel, additional, Fakunle, Adekunle, additional, Akpalu, Albert, additional, Adebayo, Philip B., additional, Nkromah, Kwadwo, additional, Yaria, Joseph, additional, Ibinaiye, Philip, additional, Ogbole, Godwin, additional, Olumayowa, Aridegbe, additional, Lakoh, Sulaiman, additional, Calys-Tagoe, Benedict, additional, Olowoyo, Paul, additional, Innocent, Chukwuonye, additional, Tiwari, Hemant K., additional, Arnett, Donna, additional, Godwin, Osaigbovo, additional, Ayotunde, Bisi, additional, Akpalu, Josephine, additional, Obiora, Okeke, additional, Joseph, Odo, additional, Omisore, Adeleye, additional, Jenkins, Carolyn, additional, Lackland, Daniel, additional, Owolabi, Lukman, additional, Isah, Suleiman, additional, Dambatta, Abdu H., additional, Komolafe, Morenikeji, additional, Bock-Oruma, Andrew, additional, Melikam, Ezinne Sylvia, additional, Imoh, Lucius Chidiebere, additional, Sunmonu, Taofiki, additional, Gebregziabher, Mulugeta, additional, Olabisi, Oluyemisi, additional, Armstrong, Kevin, additional, Onyeonoro, Ugochukwu U., additional, Sanya, Emmanuel, additional, Agunloye, Atinuke M., additional, Ogunjimi, Luqman, additional, Arulogun, Oyedunni, additional, Farombi, Temitope H., additional, Obiabo, Olugbo, additional, Obiako, Reginald, additional, Owolabi, Mayowa, additional, and As part of the HAfrica Consortium, On behalf of the SIREN Team, additional

Published
2017
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35. Exploring Overlaps Between the Genomic and Environmental Determinants of LVH and Stroke: A Multicenter Study in West Africa

Author

Adeoye, Abiodun M., primary, Ovbiagele, Bruce, additional, Kolo, Philip, additional, Appiah, Lambert, additional, Aje, Akinyemi, additional, Adebayo, Oladimeji, additional, Sarfo, Fred, additional, Akinyemi, Joshua, additional, Adekunle, Gregory, additional, Agyekum, Francis, additional, Shidali, Vincent, additional, Ogah, Okechukwu, additional, Lackland, Dan, additional, Gebregziabher, Mulugeta, additional, Arnett, Donna, additional, Tiwari, Hemant K., additional, Akinyemi, Rufus, additional, Olagoke, Ojo Olakanmi, additional, Oguntade, Ayodipupo Sikiru, additional, Olunuga, Taiwo, additional, Uwanruochi, Kelechi, additional, Jenkins, Carolyn, additional, Adadey, Patrick, additional, Iheonye, Henry, additional, Owolabi, Lukman, additional, Obiako, Reginald, additional, Akinjopo, Samuel, additional, Armstrong, Kevin, additional, Akpalu, Albert, additional, Fakunle, Adekunle, additional, Saulson, Raelle, additional, Aridegbe, Mayowa, additional, Olowoyo, Paul, additional, Osaigbovo, Godwin, additional, Akpalu, Josephine, additional, Fawale, Bimbo, additional, Adebayo, Philip, additional, Arulogun, Oyedunni, additional, Ibinaiye, Philip, additional, Agunloye, Atinuke, additional, Ishaq, Naser, additional, Wahab, Kolawole, additional, Akpa, Onoja, additional, Adeleye, Omisore, additional, Bock-Oruma, Andrew, additional, Ogbole, Godwin, additional, Melikam, Sylvia, additional, Yaria, Joseph, additional, Ogunjimi, Luqman, additional, Salaam, Abdul, additional, Sunmonu, Taofiki, additional, Makanjuola, Akintomiwa, additional, Farombi, Temitope, additional, Laryea, Ruth, additional, Uvere, Ezinne, additional, Kehinde, Salaam, additional, Chukwuonye, Innocent, additional, Azuh, Paschal, additional, Komolafe, Morenikeji, additional, Akintunde, Adeseye, additional, Obiabo, Olugbo, additional, Areo, Olusegun, additional, Kehinde, Issa, additional, Amusa, Adeniyi G., additional, Owolabi, Mayowa, additional, and HAfrica Consortium, SIREN Team as part of, additional

Published
2017
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36. Clinical Outcomes in 3343 Children and Adults With Rheumatic Heart Disease From 14 Low- and Middle-Income Countries

Author

Zühlke, Liesl, primary, Karthikeyan, Ganesan, additional, Engel, Mark E., additional, Rangarajan, Sumathy, additional, Mackie, Pam, additional, Cupido-Katya Mauff, Blanche, additional, Islam, Shofiqul, additional, Daniels, Rezeen, additional, Francis, Veronica, additional, Ogendo, Stephen, additional, Gitura, Bernard, additional, Mondo, Charles, additional, Okello, Emmy, additional, Lwabi, Peter, additional, Al-Kebsi, Mohammed M., additional, Hugo-Hamman, Christopher, additional, Sheta, Sahar S., additional, Haileamlak, Abraham, additional, Daniel, Wandimu, additional, Goshu, Dejuma Yadeta, additional, Abdissa, Senbeta G., additional, Desta, Araya G., additional, Shasho, Bekele A., additional, Begna, Dufera M., additional, ElSayed, Ahmed, additional, Ibrahim, Ahmed S., additional, Musuku, John, additional, Bode-Thomas, Fidelia, additional, Yilgwan, Christopher C., additional, Amusa, Ganiyu A., additional, Ige, Olukemi, additional, Okeahialam, Basil, additional, Sutton, Christopher, additional, Misra, Rajeev, additional, Abul Fadl, Azza, additional, Kennedy, Neil, additional, Damasceno, Albertino, additional, Sani, Mahmoud U., additional, Ogah, Okechukwu S., additional, Elhassan, Taiwo OlunugaHuda H. M., additional, Mocumbi, Ana Olga, additional, Adeoye, Abiodun M., additional, Mntla, Phindile, additional, Ojji, Dike, additional, Mucumbitsi, Joseph, additional, Teo, Koon, additional, Yusuf, Salim, additional, and Mayosi, Bongani M., additional

Published
2016
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37. Knowledge, attitudes and practices of West Africans on genetic studies of stroke: Evidence from the SIREN Study.

Author

Akinyemi, Rufus O., Adeoye, Abiodun M., Owolabi, Mayowa, Wahab, Kolawole, Sanya, Emmanuel, Kolo, Philip, Oyinloye, Olalekan, Komolafe, Morenikeji, Fawale, Michael, Ogbole, Godwin, Adebayo, Philip, Osaigbovo, Godwin, Amusa, Ganiyu Adeniyi, Imoh, Chidiebere Lucius, Sunmonu, Taofiki, Olowoyo, Paul, Sanni, Taofeeq, Chukwuonye, Innocent, Uwanruochi, Kelechi, and Olowoniyi, Peter

Subjects
*PERCEPTION testing, *STROKE, *MULTIPLE regression analysis, *HYPERTENSION, *ALCOHOL drinking
Abstract

Background It is crucial to assess genomic literacy related to stroke among Africans in preparation for the ethical, legal and societal implications of the genetic revolution which has begun in Africa. Objective To assess the knowledge, attitudes and practices (KAP) of West Africans about stroke genetic studies. Methods A comparative cross-sectional study was conducted among stroke patients and stroke-free controls recruited across 15 sites in Ghana and Nigeria. Participants' knowledge of heritability of stroke, willingness to undergo genetic testing and perception of the potential benefits of stroke genetic research were assessed using interviewer-administered questionnaire. Descriptive, frequency distribution and multiple regression analyses were performed. Results Only 49% of 2029 stroke patients and 57% of 2603 stroke-free individuals knew that stroke was a heritable disorder. Among those who knew, 90% were willing to undergo genetic testing. Knowledge of stroke heritability was associated with having at least post-secondary education (OR 1.51, 1.25–1.81) and a family history of stroke (OR 1.20, 1.03–1.39) while Islamic religion (OR=0.82, CI: 0.72–0.94), being currently unmarried (OR = 0.81, CI: 0.70–0.92), and alcohol use (OR = 0.78, CI: 0.67–0.91) were associated with lower odds of awareness of stroke as a heritable disorder. Willingness to undergo genetic testing for stroke was associated with having a family history of stroke (OR 1.34, 1.03–1.74) but inversely associated with a medical history of high blood pressure (OR = 0.79, 0.65–0.96). Conclusion To further improve knowledge of stroke heritability and willingness to embrace genetic testing for stroke, individuals with less formal education, history of high blood pressure and no family history of stroke require targeted interventions. [ABSTRACT FROM AUTHOR]

Published
2019
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40. Characteristics, complications, and gaps in evidence-based interventions in rheumatic heart disease: the Global Rheumatic Heart Disease Registry (the REMEDY study)

Author

Zühlke, Liesl, primary, Engel, Mark E., additional, Karthikeyan, Ganesan, additional, Rangarajan, Sumathy, additional, Mackie, Pam, additional, Cupido, Blanche, additional, Mauff, Katya, additional, Islam, Shofiqul, additional, Joachim, Alexia, additional, Daniels, Rezeen, additional, Francis, Veronica, additional, Ogendo, Stephen, additional, Gitura, Bernard, additional, Mondo, Charles, additional, Okello, Emmy, additional, Lwabi, Peter, additional, Al-Kebsi, Mohammed M., additional, Hugo-Hamman, Christopher, additional, Sheta, Sahar S., additional, Haileamlak, Abraham, additional, Daniel, Wandimu, additional, Goshu, Dejuma Y., additional, Abdissa, Senbeta G., additional, Desta, Araya G., additional, Shasho, Bekele A., additional, Begna, Dufera M., additional, ElSayed, Ahmed, additional, Ibrahim, Ahmed S., additional, Musuku, John, additional, Bode-Thomas, Fidelia, additional, Okeahialam, Basil N., additional, Ige, Olukemi, additional, Sutton, Christopher, additional, Misra, Rajeev, additional, Abul Fadl, Azza, additional, Kennedy, Neil, additional, Damasceno, Albertino, additional, Sani, Mahmoud, additional, Ogah, Okechukwu S., additional, Olunuga, Taiwo, additional, Elhassan, Huda H.M., additional, Mocumbi, Ana Olga, additional, Adeoye, Abiodun M., additional, Mntla, Phindile, additional, Ojji, Dike, additional, Mucumbitsi, Joseph, additional, Teo, Koon, additional, Yusuf, Salim, additional, and Mayosi, Bongani M., additional

Published
2014
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48. Sex Disparity in Blood Pressure Levels Among Nigerian Health Workers.

Author

Adeoye, Abiodun M., Adebiyi, Adewole, Owolabi, Mayowa O., Lackland, Daniel T., Ogedegbe, Gbenga, and Tayo, Bamidele O.

Abstract

Sex disparity in hypertension prevalence is well established in developed nations; however, there is paucity of data on the distribution of hypertension prevalence between the sexes in developing countries. Therefore, the authors examined sex differences in hypertension prevalence and cardiovascular risk factors in a sample of 352 healthy hospital workers in Nigeria. The mean ages of the men and women were 37.2±7.9 and 44.7±9.1 years, respectively. Thirty-five percent of participants were hypertensive, with 54% on treatment and 70% with controlled blood pressure. Men had a higher prevalence of hypertension (38.4% vs 33.0%) and prehypertension (37.6% vs 29.7%). Women had significantly higher odds of developing hypertension and of being on treatment. Mean blood pressure and fasting plasma glucose values were higher in men, while women were more often older, obese, and dyslipidemic and had a lower mean estimated glomerular filtration rate (P<.0001). These findings indicate sex disparity in blood pressure among hospital employees. Sex-focused management of hypertension is therefore advocated for hospital employees. [ABSTRACT FROM AUTHOR]

Published
2016
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