Descriptor: "AMPK and MCU" - Searchworks@Jio Institute Digital Library Search Results

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Start Over Descriptor "AMPK and MCU"

Author: Danilo Faccenda, Alessandra Baracca, Michelangelo Campanella, Claire Thornton, Giancarlo Solaini, Giulia Gorini, Adam Jones, and Danilo Faccenda, Giulia Gorini, Adam Jonesa, Claire Thorntona, Alessandra Baracca, Giancarlo Solaini, Michelangelo Campanella
Subjects: 0303 health sciences, Settore BIO/06, biology, Chemistry, chemistry.chemical_element, AMPK, Cell Biology, Calcium, Mitochondrion, CREB, IF1, Mitochondria, Cell biology, 03 medical and health sciences, ATPase INHIBITORY FACTOR 1, 0302 clinical medicine, Downregulation and upregulation, biology.protein, AMPK and MCU, Mitochondria Calcium IF1 AMPK and MCU, Uniporter, Molecular Biology, 030217 neurology & neurosurgery, 030304 developmental biology
Abstract: •IF1 regulates MCU-dependent mitochondrial Ca2+ uptake.\ud \ud •IF1 loss induces MCU upregulation through activation of the AMPK/CREB pathway.\ud \ud •OMA1 depletion restores physiological MCU levels and mitochondrial Ca2+ entry.
Published: 2021

Author: Faccenda, Danilo, Gorini, Giulia, Jones, Adam, Thornton, Claire, Baracca, Alessandra, Solaini, Giancarlo, and Campanella, Michelangelo
Subjects: *ADENOSINE triphosphatase, *MITOCHONDRIA, *CALCIUM
Abstract: • IF 1 regulates MCU-dependent mitochondrial Ca2+ uptake. • IF 1 loss induces MCU upregulation through activation of the AMPK/CREB pathway. • OMA1 depletion restores physiological MCU levels and mitochondrial Ca2+ entry. [ABSTRACT FROM AUTHOR]
Published: 2021
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