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目的探讨体质量与腰围对超重肥胖成年人的静态和动态平衡功能的影响。方法采用整群随机抽样方法抽取在中山大学附属第三医院内分泌降糖减重门诊就诊的患者（n = 103），对所有参与者进行基本资料的采集和记录、生化检测、体质量、腰围（WC）和身高测量，静态平衡功能评估采用平衡误差评分系统（BESS）及动态平衡功能评估采用功能性伸展测试（FRT）。对所有参与者的BESS评分和FRT距离根据不同身体指数（BMI）分级和WC分级分别进行组间对比。采用单因素及多元线性回归的方法对参与者静态和动态平衡功能的影响因素分别进行分析。结果① 随BMI分级增加，BESS评分呈上升趋势（P = 0.004），正常WC者的BESS评分低于中心性肥胖者（P < 0.001），结果显示与BMI正常者比较，超重和肥胖者的静态和动态平衡能力差；② 随BMI分级，增加FRT距离呈下降趋势（P P < 0.001），结果显示中心性肥胖者与WC正常者比较，中心性肥胖者的静态和动态平衡能力更差；③ BMI超重组中，随WC增加FRT距离降低，中心性肥胖者与WC正常者组间差异有统计学意义（P = 0.02），结果显示BMI无差异情况下，与正常WC比较，中心性肥胖者的动态平衡能力更差。④ BESS评分与BMI（B = 4.12，P = 0.027， 95% CI = 0.48-7.75）和WC（B = 3.47，P = 0.046， 95% CI = 0.07-6.88）的影响显著，FRT距离与BMI（B = -5.68，P = 0.001， 95% CI = -8.95-2.41）和WC（B = -4.71，P = 0.003， 95% CI = -7.83- -1.61）的影响显著，结果显示肥胖者随BMI增加其静态和动态平衡能力更差，中心性肥胖者比WC正常者的静态和动态平衡能力更差。结论腰围是超重肥胖者的动态和静态平衡功能的独立影响因素，在相同BMI情况下，中心性肥胖者比腰围正常者的动态平衡功能差，其跌倒风险更高。

【目的】研究附子多糖是否抑制血管平滑肌细胞钙化及探讨其机制是否与神经酰胺有关。【方法】我们采用氧化型低密度脂蛋白（Ox-LDL）诱导人体血管平滑肌细胞钙化，用不同浓度的附子多糖处理细胞，茜素红染色测细胞钙化，qRT-PCR检测成骨样分化标志物Msx2、Osterix、BMP2及收缩蛋白SMA的mRNA表达水平，Western blot检测Msx2、BMP2的蛋白表达水平，TUNEL法测细胞凋亡。此外，观察附子多糖对血管平滑肌细胞神经酰胺的水平及其代谢酶中性鞘磷脂酶（N-SMase）的活性的影响。【结果】附子多糖能抑制Ox-LDL诱导的血管平滑肌细胞凋亡和钙化。神经酰胺可参与Ox-LDL诱导的血管平滑肌细胞凋亡和钙化。附子多糖可降低N-SMase的活性和神经酰胺含量。【结论】附子多糖可通过调节神经酰胺信号改善血管平滑肌细胞钙化。

： 【目的】阐明nSMase2是否调控高磷高钙诱导的血管平滑肌细胞钙化。【方法】采用人血管平滑肌细 胞钙化体外模型，用高磷高钙诱导血管平滑肌细胞钙化。分别用鞘磷脂酶抑制剂GW4869和siRNA干扰敲低 nSMase2 处理血管平滑肌细胞，检测骨相关蛋白 BMP2、Runx2、Osterix 的表达和细胞钙化程度。【结果】在细胞 钙化过程中 nSMase2 的表达水平和神经酰胺的含量增高（P

文章对上下行数据流分别使用差分相移键控（DPSK）和开关键控（OOK）不同的混合调制方式,通过比较下行采用不同调制码型,在没有色散补偿的情况下,实现了20 km、上下行10 Gbit/s对称速率的传输。结果表明,使用反向归零（IRZ）码的混合调制方式可以使下行数据流具有较高的消光比,上行数据流具有较好的色散容限,从而提高了传输系统的整体性能。

【目的】 探讨320排动态容积CT血管造影对评估糖尿病眼动脉硬化的临床价值?【方法】对30例非糖尿病患者和22例糖尿病患者进行320排动态容积CT血管造影检查,对所有扫描原始数据行最大密度投影(MIP)?容积再现(VR)?多平面重建(MRP)及曲面重建(CPR),观察眼动脉的管腔情况?【结果】 320排动态容积CT血管造影检查可以清晰显示眼动脉形态?走行,以及病变的部位?情况?22例糖尿病患者血管呈不同程度粥样硬化表现?其中颅内段轻度狭窄6侧,中度狭窄4侧;视神经管内段轻度狭窄2侧,中度狭窄4侧;眶内段轻度6侧,中度狭窄2侧?斑块性质以钙化斑块或混合斑块为主?【结论】 320排动态容积CT血管造影可以对糖尿病眼动脉硬化进行无创?准确?快捷的评估,具有重要的临床价值?

【目的】探讨血管紧张素Ⅱ受体拮抗剂伊贝沙坦对糖尿病大鼠心脏的保护作用及其相关机制。【方法】将30只Wistar大鼠随机分为正常对照组、糖尿病组和伊贝沙坦组3组,每组10只。造模后12周终止实验处死大鼠,取血、尿和心脏标本,测定尿量、体质量、心脏质量/体质量、血糖、糖化血红蛋白(HbA1c);测定血液和心脏组织的丙二醛(MDA)和超氧化物歧化酶(SOD)的活性;通过电镜观察心肌超微结构的变化。【结果】12周终止实验时糖尿病各组大鼠的尿量、心脏质量/体质量、血糖、HbA1c、血清和心脏组织的MDA水平均明显高于正常组,而体质量、红细胞和心脏组织的SOD活性明显低于正常组(P

Accurate monitoring and assessment of precipitation distribution can be vital to effectively manage water resources and disaster preparedness for high productivity in modern agriculture against global climate change. Among them, Guangxi in southern China is in a monsoonal climate. A great challenge remains on the notable temporal and spatial fluctuations in precipitation, particularly for agricultural productivity and ecological integrity. The purpose of this study is to assess the suitability and precision of the monthly IMERG (V06) precipitation dataset in the Guangxi region. A scientific foundation was then established to manage the local water resources and disaster preparedness. The study area was characterized by low rainfall (≤1300 mm/a), moderate rainfall (>1300-1700 mm/a), and high rainfall (>1700 mm/a). The performance of the IMERG Early, Late, and Final products was also elucidated across the different zones. The baseline data of monthly precipitation was collected from 91 meteorological stations in the period from 2001 to 2020. Three quantitative indexes were employed, including the metrics-correlation coefficient (CC), root mean square error (RMSE), and relative error (RE). A comprehensive analysis was conducted on the precision of IMERG products at the various spatial and temporal scales, as well as precipitation intervals. Results indicate that: 1) Both Early and Late products exhibited similar precision to underestimate the overall precipitation, whereas the Final product tended to overestimate the precipitation. 2) The increase in precipitation caused a decrease in the CC and RE for all products, while an increase in RMSE. The deviation thresholds after monthly precipitation estimation were 271, 272, and 351 mm for the Early, Late, and Final products, respectively. Once the actual monthly precipitation fell below these thresholds, an overestimation occurred and vice versa. 3) Spatially, the IMERG products demonstrated that there was a stronger correlation and greater variability in the areas with the higher precipitation, with the overestimation in the regions under low or moderate rainfall, and the underestimation under high rainfall. 4) Temporally, the precision of products was higher in the dry season during drought years. The Early and Late products performed adequately in autumn, indicating noticeable underestimations. The final product excelled in winter. 5) A decreasing trend was found in the precision of the Final product over the whole years, whereas, an ever-growing overestimation was in the Early and Late products. In conclusion, the precision of the monthly-scale IMERG product was notably influenced by the precipitation, indicating considerable discrepancies in the various regions and temporal scopes. Hence, it is recommended to conduct customized evaluations of product precision for the specific regions and time frames in practical applications. This finding can serve as a significant reference to monitor and manage the water resources for beneficial insights into the climate zones. [ABSTRACT FROM AUTHOR]

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目的　对比观察阿奇霉素、多西环素静脉滴注治疗小儿肺炎支原体肺炎 (MMP)临床效果。方法 MPP 患儿 515例，根据治疗方法不同分为 3组，国产阿奇霉素组 (61例，均为 2023年 10月住院患儿)静滴国产阿奇霉素， 进口阿奇霉素组 (105例，均为2023年10月住院患儿)静滴进口阿奇霉素，多西环素组 (2023年9月住院患儿30例、 2023年10月住院患儿90例、2023年11月住院患儿114例、2023年12月住院患儿115例)静滴多西环素，比较各组用 药后退热时间、咳嗽缓解时间、肺部啰音消失时间、住院时间及全血WBC、全血CRP、血浆IL-6、血浆LDH水平和激 素使用率、支气管镜使用率、合并感染率、不良反应发生率。结果　与进口阿奇霉素组比较，国产阿奇霉素组退热时 间、咳嗽缓解时间短，多西环素组啰音持续时间短 (P均<0. 05)；与 2023年 11月住院患儿比较，多西环素组 2023年 10月住院患儿咳嗽缓解时间长，2023年12月住院患儿啰音持续时间长 (P均<0. 05)；与2023年12月住院患儿比较， 多西环素组2023年9月和11月住院患儿咳嗽缓解时间、肺部啰音消失时间短 (P均<0. 05)。3组全血WBC、CRP及 血浆IL-6、LDH水平比较无统计学差异 (P均>0. 05)，多西环素组不同时间全血 WBC、CRP 及血浆 IL-6、LDH 水平 比较无统计学差异 (P 均>0. 05)。国产阿奇霉素组、进口阿奇霉素组、多西环素组激素使用率比较无统计学差 异 (P均>0. 05)；多西环素组2023年9月住院患儿、2023年10月住院患儿、2023年11月住院患儿、2023年12月住院 患儿激素使用率比较无统计学差异 (P均>0. 05)。国产阿奇霉素组、进口阿奇霉素组、多西环素组支气管镜使用率 比较无统计学差异 (P均>0. 05)；与2023年10月住院患儿比较，多西环素组2023年12月住院患儿支气管镜使用率 高 (P<0. 05)。国产阿奇霉素组、进口阿奇霉素组、多西环素组合并感染率比较无统计学差异 (P均>0. 05)；与 2023 年10月住院患儿比较，多西环素组2023年12月住院患儿合并感染率高 (P<0. 05)。与进口阿奇霉素组比较，多西环 素组不良反应发生率高 (P<0. 05)；多西环素组2023年9月住院患儿、2023年10月住院患儿、2023年11月住院患儿、 2023年 12月住院患儿不良反应发生率比较无统计学差异 (P 均>0. 05)。结论　阿奇霉素和多西环素在治疗 MMP 的有效性和安全性有差异，多西环素改善啰音方面优于国产和进口阿奇霉素，不良反应发生率高于国产和进口阿奇 霉素，国产阿奇霉素和进口阿奇霉素在疗效和安全性无显著性差异。不同季节 (月份)合并不同感染会影响多西环 素治疗MMP的效果，临床在治疗期间需要根据患儿的具体情况及流行病学提供合理有效的诊疗方案。 [ABSTRACT FROM AUTHOR]

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肥胖和糖尿病及其并发症的发生密切相关, 因而减重对于预防糖尿病的发生发展非常 重要。减重手术的疗效确切, 但仍存在一定局限性。近几年, 新型降糖药物的减重效果表现尤为亮 眼, 药物治疗是否可以替代减重手术？该文分别从减重手术和新型降糖药物的优缺点方面展开阐述, 认为药物和手术治疗都是目前在减重降糖治疗中的有效手段, 临床上应该根据实际情况选择最适合 患者的安全有效的减重治疗方法。 [ABSTRACT FROM AUTHOR]

In order to realize the resource utilization of waste resources, the pig-breeding litters from the microbial fermentation bed were used to develop the tomato seedling substrate. By selecting the pig-breeding litters used in the microbial fermentation bed for one year, its leaching liquor was extracted and diluted into different concentrations. The germination of tomato seeds was used as an indicator to screen the appropriate amount of litter in the substrate. Then, the basic substrate formula was determined by the plug seedling experiment, and the usage of N, P and K was further optimized. Finally, the tomato seedling substrate formula was determined. The results showed that the formula for the preparation of tomato seedling substrate by using the pig-breeding litters from the microbial fermentation bed was as follows: the ratio of litter to coconut husk was 3∶7 (volume ratio), the dosage of N was 0.3 kg·m−3, the dosage of P was 0.2 kg·m−3, and the dosage of K was 0.1 kg·m−3. By using the prepared substrates for the tomato seedling, the emergence rate of seedlings could reach up to 98%, and the plant height, stem diameter and root length of the seedlings were all significantly better than those of the commercial peat substrate (the control group). After these seedlings were transplanted in the field, the plant height and bearing fruit number of tomato seedlings in the field were significantly better than those of the control group. The preparation of tomato seedling substrate could realize the resource utilization of pig-breeding litters from the microbial fermentation bed. [ABSTRACT FROM AUTHOR]

Copyright of Journal of the Chinese Society of Rare Earths is the property of Editorial Department of Journal of the Chinese Society of Rare Earths and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Diagnosis & Therapy on Dermato-venereology is the property of Dermatology Hospital of Southern Medical University and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)