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Copyright of Modern Preventive Medicine is the property of Modern Preventive Medicine Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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Copyright of Journal of Shanghai Jiao Tong University (1006-2467) is the property of Journal of Shanghai Jiao Tong University Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Computer Engineering & Applications is the property of Beijing Journal of Computer Engineering & Applications Journal Co Ltd. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

嗜铬细胞瘤/副神经节瘤（PPGL）是起源于肾上腺髓质或肾上腺外副神经节的副神经节瘤, 可导致难治性 高血压和高血压危象。在第 5 版世界卫生组织的神经内分泌肿瘤分类中 PPGL 被认为是恶性肿瘤。有研究建立了 联合临床、病理、分子标志物的预测模型评估 PPGL 的转移风险；间碘苄基胍（MIBG）显像和 18F-脱氧葡萄糖 PET/CT 对定位转移性 PPGL 的灵敏度和特异度明显优于 CT; 大约 40% 的 PPGL 与已知致病基因的胚系突变有关, 因此基因 检测可用于肿瘤复发或多发的诊断。手术切除是治疗 PPGL 最有效的方法, 然而对于转移性 PPGL 而言只能作为一 种姑息性选择。化疗对转移性 PPGL 整体效果不佳, 131I-MIBG 和肽放射性核素治疗转移性 PPGL 更有优势。目前抗 血管生成的酪氨酸激酶抑制剂以及程序性死亡受体 1 免疫检查点抑制剂的治疗价值有限, 但随着新靶点的发现, 靶 向药物仍具有巨大潜力。 [ABSTRACT FROM AUTHOR]

Appetite is regulated by an interaction between central and peripheral signals. The Daurian ground squirrel (Spermophilus dauricus) is a typical fat-storing hibernating animal. To explore the difference in appetite related neuroendocrine response in hibernating animal between winter(hibernating period) and summer(active period), the immunoreactive(IR) neuron expression of c-Fos, neuronal nitric oxide synthase (nNOS), neuropeptide Y (NPY) of the hypothalamus using immunohisochemistry methods, and the concentration of serum ghrelin (GHRL) and corticotropin releasing hormone(CRH) using enzyme-linked immunosorbent assay (ELISA) methods were examined in Daurian ground squirrels during summer and winter. In contrast to summer, c-Fos-IR expression in the arcuate nucleus(ARC), paraventricular nucleus (PVN), ventromedial hypothalamus (VMH), lateral hypothalamic area (LHA), and dorsomedial hypothalamic nucleus (DMH) decreased significantly in winter. The nNOS-IR neurons were expressed in the same way except for the ARC. The NPY-IR neurons in the ARC and VMH in winter were significantly lower than those in summer, while the LHA NPY-IR neu⁃ rons in winter was significantly higher than those in summer. Furthermore, the serum GHRL concentration in winter were significantly lower than that in summer, while the serum CRH concentration in winter were significantly higher than that in summer. These results suggest that the Daurian ground squirrel exhibits weak neuronal activation in the hypothalamus dur⁃ ing winter, and the release of nitric oxide, NPY, GHRL and CRH exhibit a flexible physiological adaptation to hibernation. These findings will allow us to better comprehend the seasonal modulation of appetite by central and peripheral system in hi⁃ bernating animals. [ABSTRACT FROM AUTHOR]

Copyright of Journal of Beijing University of Traditional Chinese Medicine is the property of Journal of Beijing University of Traditional Chinese Medicine and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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Copyright of Journal of Central China Normal University is the property of Huazhong Normal University and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Chinese Journal of Aesthetic & Plastic Surgery is the property of Chinese Journal of Aesthetic & Plastic Surgery Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

瘢痕疙瘩是胶原过度增生引起的一种真皮纤维增殖性疾病。采用间充质干细胞（mesenchymal stem cells, MSCs）治 疗瘢痕疙瘩已成为近期主要的研究方向。研究表明，MSCs 预防和治疗瘢痕疙瘩的机制是通过对伤口愈合的细胞因子表达的趋 化性及对炎性细胞的调控作用，对成纤维细胞的活性、增殖、迁移的影响及通过抑制胰岛素样生长因子结合蛋白-7（Insulin-like growth factor binding protein, IGFBP-7）的表达，从而抑制血管形成，促进基质蛋白酶的分泌，降低内皮纤溶酶原激活物抑制剂 （plasminogenactivator inhibitor-1, PAL-1）的表达，并通过增加核心蛋白聚糖的表达影响胶原重塑，从而降低纤维化。由于MSCs 对瘢痕疙瘩形成的病理生理机制均有不同程度的影响，因而可为瘢痕疙瘩的治疗提供一种较新的途径。 [ABSTRACT FROM AUTHOR]

Copyright of Journal of PLA University of Science & Technology (Natural Science Edition) / Jiefangjun Ligong Daxue Xuebao is the property of Magazine of PLA University of Science and Technology and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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Copyright of Electric Machines & Control / Dianji Yu Kongzhi Xuebao is the property of Electric Machines & Control and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)