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利用一种新型的环形石墨炉加热的改进的化学汽相沉积（MCVD）车床制作出了高吸收、低背景损耗单包层高掺Yb3+石英光纤,并对其几何参数和吸收谱进行了测量、分析和讨论,得出了高掺Yb3+石英光纤的制作要点在于高质量疏松层的制作的结论,并分析了疏松层中掺P有助于提高掺Yb3+量的机理。制作出的高掺Yb3+单包层石英光纤样品在976 nm波长下的吸收可达594 dB/m,而背景损耗只有0.1 dB/m。

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Electrospinning can prepare bio⁃scaffold materials that mimic extracellular matrix, and good biocompatibility can be obtained by using poly⁃caprolactone (PCL) as the raw material. The combination of PCL electrospun nanofibers with inorganic materials can improve the hydrophilic and mechanical properties of scaffold materials, regulate the degradation performance and enhance the biomineralization ability, which has promising applications. In this paper, we review the application of PCL electrospun nanofiber⁃ based hybrid biomaterials in dentistry. [ABSTRACT FROM AUTHOR]

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口腔扁平苔藓 (oral lichen planus, OLP) 是发生于口腔黏膜的一种慢性炎症性疾病. OLP主要组织病理学 表现为上皮下密集的T淋巴细胞呈带状浸润和基底细胞液化变性. 根据是否表达CD4或CD8, T细胞可分为CD4 + T 细胞和CD8 + T细胞, 其中CD8 + T细胞直接参与了OLP的发生发展, 其主要作用是促进上皮组织中角质形成细胞的 凋亡, 破坏口腔黏膜的基底膜, 而 CD4 + T 细胞则通过分泌相关细胞因子辅助 CD8 + T 细胞发挥作用. 根据作用功 能, T细胞可分为辅助性T淋巴细胞 (Th), 细胞毒性T淋巴细胞 (CTL) 和调节性T细胞 (Treg), 其中Th1分泌TNF-α与 IL-1可协同增加MHC Ⅰ及Ⅱ类抗原, 黏附分子和趋化因子表达, 促进OLP的慢性炎症反应; Th9分泌的IL-9可促进 OLP组织MMP9水平升高, 进一步加重OLP, Th17可协同作用Th9的促炎作用; Th17分泌的IL-17可刺激上皮细胞, 内皮细胞, 成纤维细胞产生多种细胞因子, 如IL-6, IL-8, 粒细胞—巨噬细胞集落刺激因子及细胞黏附因1等, 促进炎 症的发生发展; Th22分泌IL-22, IL-13和TNF-α参与上皮组织的炎症反应, 同时表达CC亚族类趋化因子受体, 促进T 细胞的迁移, 诱导角质形成细胞分泌多种促炎因子参与炎症反应, 抑制角质形成细胞的增殖和迁移分化; Tregs通过 调节IL-35, IL-15等细胞因子参与维持机体免疫稳态, Th17/Treg失衡导致OLP的发生发展. [ABSTRACT FROM AUTHOR]

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Eichhornia crassipes has become one of the most serious malignant aquatic weeds in recent years due to its separation from the restriction of natural enemies and natural factors, in addition to its extremely strong ability to reproduce and spread. The use of biological control method to control Eichhornia crassipes is recognized as a safe and effective method at home and abroad. Eichhornia crassipes has been introduced in Quanzhou for several decades, and it may produce microbial natural enemies in the adaptation process of Eichhornia crassipes. The disease investigation of Eichhornia crassipes was carried out in the agricultural science and technology park of Quanzhou Institute of Agricultural Sciences. It was found that the leaf blight of Eichhornia crassipes was the most obvious in the water area, which could cause the large area of Eichhornia crassipes leaves to wilt. Two pathogenic fungi causing the leaf blight of Eichhornia crassipes were isolated and obtained by means of isolation, pur辻ication and ident辻ication of pathogenic fungi. Combined with the morphological analysis of strains and ITS sequence analysis, they were identified as Alternaria alternate YQ21 and Alternaria brassicicola YQ36. Alternaria brassicicola YQ36 was the first discovered pathogen of Eichhornia crassipes in Fujian Province, which enriched the resource library of natural enemy microorganisms of Eichhornia crassipes in Fujian Province. [ABSTRACT FROM AUTHOR]

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