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In order to study the county development and land use of Jingyuan County, Landsat remote sensing image data and statistical yearbook data in 2000, 2005, 2010, 2015 and 2020 were selected to analyze changes of land use structure by land use dynamic degree and land use transfer matrix, and the main driving factors were studied by principal component analysis. The results showed that overall, the single land use dynamic degree of construction land was the largest and the degree of change was the most severe, and the land use dynamic degree of forest land was all positive. The area of unused land, cultivated land and construction land increased, the area of forest land and water area changed little, and the area of grassland decreased. In the past 20 years in Jingyuan County, the unused land area increased most significantly, followed by the construction land and cultivated land. The grassland area decreased more. The main driving factors of land use change in Jingyuan County were closely related to people’s living standards, agricultural and economic development levels. [ABSTRACT FROM AUTHOR]

To improve the heat storage capacity of a salt gradient solar pond(SGSP), a full understanding on the thermal and solutal transfer characteristics is needed. Lattice Boltzmann method was adopted to numerically simulate the double diffusive convection and entropy generation inside an internal heating enclosure attaching with a porous layer. The influence of internal heat generation, Darcy number, Soret and Dufour effect on heat and mass transfer rates and entropy generation was deeply discussed. Results show that attaching a porous layer at the bottom is beneficial to inhibit the heat and mass transfer rates, and blindly reducing Darcy number has no significant influence. Increasing internal heat generation can also suppress the heat and mass transfer rates. Soret effect can improve the solutal transfer process, while Dufour effect has positive influence on thermal transfer process. Furthermore, porous layer for lower Darcy number can inhibit the entropy generation. Internal heat generation can enhance the entropy generation, and thermal irreversibility has dominant effect for large internal heat generation. Soret effect has no mild influence on entropy generation, while Dufour effect promotes the entropy generation. Under the stronger Dufour effect, thermal irreversibility dominates the total entropy generation. [ABSTRACT FROM AUTHOR]

Aiming at the problems of low efficiency and large error in the registration of two partially overlapped point clouds, this paper proposed a point cloud registration algorithm based on the mixed-features sampling for overlapping domain. First, it used coding and feature interaction predicted the overlap score of each point to obtain richer point cloud features. Second, it extracted the local geometric features of overlapping points and retained the overlapping key points based on overlapping scores and the significance of point features. Finally, it used the geometric information and spatial information of overlapping key points to construct a hybrid feature matrix, calculated the matching similarity of the matrix, and obtained registration results by using weighted singular value decomposition. Experimental results show that the proposed method has strong generalization ability and can significantly improve the registration accuracy of point cloud while ensuring registration efficiency. [ABSTRACT FROM AUTHOR]

Objective: The incidence rate of prostate cancer (PCa) is high in older men. To date, no immune markers are available to predict the survival rate of PCa patients. Therefore, it is necessary to explore the immunological properties of PCa. Methods: RNA-seq analysis results of 499 PCa and 52 normal prostate tissue samples and their clinical data were first retrieved from the database of the Cancer Genome Atlas (TCGA). Total of 317 differentially expressed immune-related genes were found between PCa and normal prostate tissues, and 9 common key genes were obtained after taking an intersection with 1988 prognostic genes, Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment analyses were performed on the nine differential genes in the normal group and the tumor group. The immune genes among the differentially expressed genes were further obtained for univariate and multivariate Cox and Lasso regression analysis, and four independent immune genes IGHV7-81, NOX1, MPO, and BMP7, were associated with prognosis which were applied to establish an immune risk score model. Results: Kaplan-Meier results showed that high expression of IGHV7-81 indicated poor prognosis, while low expressions of NOX1 and MPO indicated poor prognosis. A nomogram combining multiple clinical information and IRSS-related immune genes was more effective in predicting outcome than a single independent prognostic factor. Subsequently, an immune-related PCa prediction model was successfully constructed and validated, and it can independently predict the survival of PCa patients. PCa Patients with high immune risk had a poor prognosis. Clinical tissue samples analysis further verified that low expression of the immune gene BMP7 was associated with unfavorable prognosis in PCa patients. Conclusion: Overall, the identified four key genes (IGHV7-81, NOX1, MPO, and BMP7) could be used as independent PCa prognostic factors. Analysis of tissue samples indicated that BMP7 had a good predictive ability in PCa patients. [ABSTRACT FROM AUTHOR]

In order to study the different stages of aging asphalt fatigue performance, scanning linear amplitude（LAS） and dielectric constant were tested on the heat and oxygen aging, ultraviolet light, and water coupling before and after the 90 # matrix asphalt, SBS modified asphalt, from two angles of damage accumulation and phase angle change discussed the change of the different stages of aging asphalt fatigue performance. The relationship between the slope absolute value B of asphalt component and fatigue strain curve based on dielectric properties, fatigue failure strain εd and fatigue life Nf based on damage and fatigue failure strain εθ and fatigue life N′f based on phase angle were analyzed. The results show that the longer the aging degree, the shorter the fatigue life of asphalt, and the greater the strain sensitivity of asphalt based on fatigue resistance. The results show that the longer the aging degree, the shorter the fatigue life of asphalt, and the greater the strain sensitivity of asphalt based on fatigue resistance. It is reasonable and feasible to use the failure strain εD and fatigue life Nf defined by the damage-based fatigue failure criterion to evaluate the anti-fatigue performance of asphalt, and it is consistent with the analysis results of the failure strain ε? and fatigue life N′f defined by the phase angle fatigue failure criterion. It can be seen that the method to divide asphalt components based on dielectric properties is reasonable and feasible, and can be correlated with asphalt pavement performance to further guide the asphalt modification process. [ABSTRACT FROM AUTHOR]

The goals of orthodontic treatment are balance, stability and aesthetics, an important physiological foundation for achieving the above goals is a good occlusal relationship, which includes static and dynamic occlusion. The evaluation of occlusal efficacy involves the static occlusal indicators such as overbite, overjet, midline and molar relationship at the intercuspal position (ICP), as well as the dynamic occlusion during the centric and non-centric excursions. The PAR index represents the degree of deviation from the ideal occlusion, and the occlusal alternations can be quantitatively evaluated by comparing the differences in PAR index before and after orthodontic treatment. The T-scan digital occlusal system can be used to evaluate the dynamic occlusion because of its characteristics of "force and time" correlation. In this paper, the advantages of PAR index combined with T-SCAN occlusal system in evaluating the occlusal efficacy of orthodontic treatment were reviewed. [ABSTRACT FROM AUTHOR]

[Objective] The aim of this paper was to explore the function of LEA3 gene and the molecular mechanism of drought resistance of Festuca Arundinacea, for which LEA3 gene from two Guizhou native F. Arundinacea cultivars ( Qiancao 1 and Qiancao 2) were cloned and the bioinformatics of LEA3 genes and their expression under drought stress at seedling stage were analyzed as well. [Method] In this experiment, we cloned LEA3 genes of Qiancao 1 and Qiancao 2 by RT-PCR, referring to the sequences recorded by NCBI. At the same time, the amino acid sequence was analyzed by relevant software, and the expression of amino acid under drought stress was analyzed by real-time fluorescence quantitative PCR ( qRT-PCR). [ Result ] In this study, we found that LEA3 genes in Qiancao 1 and Qiancao 2 consisted of open reading frame (ORF) of 609 bp and 642 bp respectively, which encoded proteins of 203 and 213 amino acids residues, respectively. Compared with Qiancao 2, the LEA3 protein of Qiancao 1 lacks the motif composed of 11 amino acids. At the same time, 11 amino acid differences were found between Qiancao 1 and Qiancao 2. Bioinformatics analysis showed that the molecular weight of Qiancao 1 LEA3 protein was 20. 72 kDa, the isoelectric point was 8. 55, and the grand average of hydropathicity ( GRAVY) was - 0. 971. The LEA3 protein of Qiancao 2 has a molecular weight of 22. 01 kDa, an isoelectric point of 8. 99, and a GRAVY of - L 069. The hydrophobicity analysis showed that both Qiancao 1 and Qiancao 2 LEA3 proteins had no transmembrane structure, and the hydrophilicity of Qiancao 2 LEA3 was stronger than that of Qiancao 1 LEA3. Alpha-helixes are dominant in Qiancao 1 and Qiancao 2 LEA3 proteins. LEA3 proteins of Qiancao 1 and Qiancao 2 have high homology with that of barley, goatgrass, wheatgrass and wheat. The phylogenetic tree showed that LEA3 proteins of Qiancao 1, Qiancao 2, wheat, ryegrass, barley, goatgrass, bromus inermis and wheatgrass were clustered into one group. The results of qRT-PCR analysis showed that the expression of Qiancao 1 LEAJ was higher than that of Qiancao 2 in the whole process of drought stress at seedling stage. Compared with mild stress, the response of LEA3 in Qiancao 1 and Qiancao 2 under severe stress was stronger. [ Conclusion] It was found that the drought resistance of Qiancao 1 and Qiancao 2 was positively correlated with the expression of I.EAJ gene. Under the same conditions of drought stress, the expression of Qiancao 1 LEAJ gene was higher than that of Qiancao 2. Therefore, it can be inferred that Qiancao 1 is more adaptable to arid environment than Qiancao 2. [ABSTRACT FROM AUTHOR]

[Objective]This paper aimed to screen out the comprehensive evaluation system of cold tolerance of cowpea in adult stage, to explore the best index of cold tolerance evaluation of cowpea in adult stage and to obtain strong cold tolerance germplasm resources in cowpea adult stage. [Method]Fifty cowpea cultivars were used as tested materials, and five morphological traits such as chilling injury index, crude nodal weight, tender pod weight, yield per plant, pods per plant and average pod length were determined by die method of natural low temperature. Conductivity, chlorophyll content, chlorophyll b content, chlorophyll content, soluble protein content, soluble sugar content, catalase activity, peroxidase activity, superoxide dismulase activity, ascorbate peroxidase activity, superoxide anion content, malondialdehyde content, free proline content of 13 physiological indicators were also measured. Principal component analysis, membership function analysis, cluster analysis and regression analysis were conducted to evaluate lhe cold tolerance of cowpea at adult stage. [Result] The cold tolerance of cowpea in adult stage was significantly positively correlated with the tender pods, yield per plant, pod number, pod length, chlorophyll content, soluble protein content, peroxidase activity and superoxide dismulase activity, and significantly negatively correlated with the relative values of conductivity, soluble sugar content, malondialdehyde content, free proline content. Through principal component analysis, 13 significant individual indicators were converted into 7 mutually independent comprehensive indexes. The D value of cold tolerance was obtained by using the membership function analysis, and the cold tolerance of the 50 cowpea varieties was divided into 4 categories by cluster analysis method. Using regression analysis, the optimal regression equation for evaluating cold tolerance of different cowpea varieties at adult stage was established; D= -0.481 +0.210*X1 +0.157 X3 +0.494 X5 +0.128X10 +0.178X11. The cold tolerance index, relative yield per plant, relative pod length degree, relative activity ol superoxide disniulase and relative activity of peroxidase could he used as effective indicator’s to evaluate the cold tolerance of cowpea at adult stage. [Conclusion] 1 cowpea gemiplasm with extremely strong cold tolerance and 12 cowpea germplasms with strong cold tolerance were obtained. [ABSTRACT FROM AUTHOR]

Landslide instability is a gradual change to the process of mutation and there will always be some warning before the destruction. The main purpose of landslide monitoring is to find and take measures. This paper studied on landside comprehensive monitoring in Xiaolangdi, by installing 25 surface deformation monitoring points and 3 deep deformation monitoring points at key locations landslide, which integrated multi-level monitoring system by all the monitoring points. The monitoring data analysis shows that: the geological structure of the landslide was divided into front slump, in the postmedian of the sliding mass and a trailing edge crack body. The mechanical divisions are colluvial slope sediments, cataclastic rock mass, fracture, bedrock four classes. And the deformation trend and influencing factors of the landslide surface and the deep part were analyzed. [ABSTRACT FROM AUTHOR]

Objective　To compare the clinical efficacy of invisible appliance and fixed appliance in the treatment of skeletal class I malocclusion. Methods A prospective cohort study with a minimum sample size of no less than 19 subjects in each group was used，and 46 adult patients with bone type I were eventually enrolled. According to the type of appliance，they were divided into the invisible appliance group（group A） with 25 patients and the fixed appliance group（ group B） with 21 patients. Data were analyzed before orthodontic treatment（ T0） after（T1） between invisible and traditional fixed orthodontics. Results　The static occlusion index and PAR score were improved after treatment，and the differences were statistically significant（P< 0.01）. The occlusal dynamic parameters including OT，OFAT，OFPT，AOF and DT were significantly improved after treatment（ P< 0.01） . There were significant differences in AOF，forward and lateral DT between the two groups（P< 0.01），the invisible group was better than the fixed group. Conclusion　Both the dynamic and static occlusal changes can be greatly improved with invisible and fixed appliance in the treatment of patients with class I malocclusion. Invisible appliance is better than fixed appliance in balancing occlusion，eliminating and reducing occlusal interference. [ABSTRACT FROM AUTHOR]

In order to study the problem of damage to typical targets by naval guns and weapons of coast guard vessels in rights protection law enforcement tasks and improve the operational capability of naval guns and weapons of coast guard vessels, a simulation model and simulation process are constructed. Through simulation calculation of the damage probability and ammunition consumption expectation of different targets, the relationship between the damage probability of typical tar- gels, ammunition consumption expectation and shooting distance are analyzed. Furthermore, the destructive firing strategies of different typical targets are obtained. The research results can provide reference for coast guard vessels to carry out the task of safeguarding rights. [ABSTRACT FROM AUTHOR]

Objective To observe the maxillary alveolar bone density changes in patients with mild-to-moderate chronic periodontal disease and different periodontal biotypes at alignment and leveling arch stage. Methods 20 cases of adult female patients were selected randomly and were divided into group in accordance to the periodontal status, periodontal biotypes and different teeth movement. The maxillary alveolar bone density was measured by Cone beam CT (CBCT) . Results After treatment，bone mineral density in different periodontal status was decreased (P ＜0.05)； reduce periodontal disease to the labial movement in the root apical， labial palatal bone density ratio was greater than the thickness of thin type gingival type (P＜0.05)；lower lip to mobile thin gingival periodontal disease group in the root of neck the middle and apical labial and palatal alveolar bone density was greater than the ratio of periodontal health group (P＜0.05)；mobile palatal periodontal disease group in the root of neck lip，palate side reduction ratio is greater than the periodontal health group (P＜0.05)；lower lip thickness of gingival and periodontal disease to the mobile group in the labial and root neck in the root， the tip of the palatal bone density was greater than the ratio of periodontal health group (P＜0.05) ; mobile palatal periodontal disease group in the root decreased rate was larger than the labial periodontal health group (P ＜0.05). Conclusions The alveolar bone density may be greatly changed in the periodontal disease group after the leveling and aligning of orthodontic treatment. At the beginning of the orthodontic treatment，we should pay more attention on the periodontal biotype to avoid maxillary alveolar bone absorbing. [ABSTRACT FROM AUTHOR]

目的 研究分析人工股骨头置换术与髋关节置换术治疗骨质疏松性股骨颈骨折的临床效果。方法 选取2016年1月至2017年12月该院诊治的68例骨质疏松股骨颈骨折老年患者作为研究对象,将其分为对照组和观察组,对照组采用全髋关节置换术治疗,观察组采用人工股骨头置换术治疗,对比分析两组临床疗效。结果 观察组术中出血量、手术时间及下地时间均明显低于对照组,差异均有统计学意义(P<0.05);但住院时间比较,差异无统计学意义(P>0.05)。术后6个月,观察组优良率[85.29%(29/34)]明显低于对照组[91.19%(31/34)],差异有统计学意义(Z=5.028,P=0.001)。术后6个月,对照组不良反应率[17.65%(6/34)]明显低于观察组[11.76%(4/34)],但差异无统计学意义(χ2=0.752,P=0.424)。结论 若患者年龄较大、身体综合素质差,可采用人工髋关节股骨头置换术;若患者身体素质较高,对髋关节功能恢复较高,选择全髋关节置换术。 [ABSTRACT FROM AUTHOR]

There has been a significant increase in the number of patients with alcoholic pancreatitis in recent years, and the pathogenesis of alcoholic pancreatitis is associated with various factors including genetic factors, smoking, and gut microbiota. Alcoholic pancreatitis is different from other types of pancreatitis in epidemiological features and clinical manifestations. This article reviews the research advances in the epidemiological features, pathogenesis, clinical manifestations, treatment, and prognosis of alcoholic pancreatitis. [ABSTRACT FROM AUTHOR]

Objective： To study expressions of hMSH6 and P53 in sporadic colorectal carcinoma (SCC) and their relation with SCC pathological features. Methods： Immunohistochemical Max-Vision two-step method was applied to detect the hMSH6 and P53 expression in 48 cases of SCC tumor tissue, adjacent tissue of 3-9 cm next to neoplastic loci and colon tissue of 10cm next to neoplastic loci, as well as that in 45 cases of normal colon tissue. Results： The positive expression rate of hMSH6 was lower in cancer tissues and adjacent tissues of 3-9 em next to neoplastic foci than in colon tissues of 10 cm next to neoplastic loci and normal colon tissues, while the positive expression rate of P53 was higher cancer tissues and adjacent tissues of 3-9cm next to neoplastic foci than in colon tissues of 10 cm next to neoplastic foci and normal colon tissues. The differences were statistically significant (P<0.05). hMSH6 expression was correlated with the loci location and depth of invasion (P<0.05). P53 positive expression was correlated with histological grade (P<0.05). The hMSH6 expression was negatively correlated with P53 (r=-0.403, P<0.05). Conclusion： The abnormal expression of hMSH6 and P53 involved in the process of occurrence and development of SCC. The hMSH6 and P53 can be used as evaluation indicators of SCC biological behavior. [ABSTRACT FROM AUTHOR]

In order to investigate the high and low temperature performance of silicone rubber powder (SRP)-SBS compound modified asphalt, nine kinds of modified asphalt with different mixing ratios compounded were used. By the conventional test and the analysis method of the asphalt rheology test, the effects of SRP and SBS content on the viscoelasticity of the compound modified asphalt were qualitatively and quantitatively analyzed by the conventional test and the analysis method of the asphalt rheology test. When we analyzed the results of low temperature bending beam rheometer test, in order to comprehensively consider the creep rate and the flexural creep, the ratio of this two values and low grade temperature were, and the low temperature performance of compound modified asphalt comprehensively and accurately analyzed. With the frequency sweep test at multiple temperatures, the master curve of the complex shear modulus of the compound modified asphalt was constructed, and modified asphalt under different mixing ratios in a wide frequency range analyzed the performance differences of the compound. For studying the situation under extreme frequency, the improved CAM (Christensen-Andersen-Marastean) model was introduced to analyze the high temperature performance of compound modified asphalt. It shows that the compound modified asphalt has good high and low temperature performance, and the recommended compounding ratio is 17. 5% SRP + 4% SBS. [ABSTRACT FROM AUTHOR]

In order to further study the modification mechanism and fatigue characteristics of high modulus RCA modified asphalt, its performance is measured by three indexes, Brockfield viscosity, infrared spectrum, linear amplitude scanning and dielectric constant test. The basic indexes, fatigue properties, functional group changes of asphalt and the changes of asphalt components based on dielectric properties with different modifier contents are discussed, and grey correlation degree between the components and asphalt pavement performance index is analyzed. The results show that the optimum content of RCA modifier is 16.7% of asphalt mass. The modification of asphalt by RCA modifier is physical modification. Under low strain, the fatigue performance of RCA modified asphalt is better than that of base asphalt, and the strain dependence is higher. The fatigue life calculated by the new asphalt fatigue failure criterion has a good correlation with the fatigue life of asphalt mixture, and it is feasible to evaluate the fatigue resistance of RCA modified asphalt. [ABSTRACT FROM AUTHOR]

This article put labor, capital, and energy factors into the consideration of biased technological progress, and used the directional distance function and Malmquist-Luenberger index to measure, identify, and compare the direction of biased technological progress in Chinese industries from 2003 to 2019. The study used the FGLS model to investigate the factors affecting industrial biased technological progress under the cases of no environmental constraints, weak environmental constraints, and strong environmental constraints, respectively. The results showed that: ‡@ Ignoring environmental constraints overestimated the total factor productivity index and the technological progress index. The total factor productivity index and technological progress index were significantly lower in the weak and strong constraint cases compared to the no constraint case. ‡A When there was no environmental constraint, the direction of industrial technological progress was mainly characterized by labor saving/capital use, labor saving/energy use, and capital use/energy saving; after adding the environmental constraint, the direction of technological progress was mainly characterized by labor use/capital saving, labor saving/energy use, and capital saving/energy use. ‡B The direction of Chinaf s industrial technological progress under environmental constraints was mainly influenced by environmental regulations, foreign direct investment, R&D intensity, openness to foreign trade, per capita capital stock, and energy production efficiency. The effect of environmental regulation on biased technological progress with no and weak environmental constraints showed an inverted eUf shape and had a positive effect on biased technological progress with strong environmental constraints. The labor-based FDI significantly hindered the biased technological progress with no and strong environmental constraints, while the capital-based FDI only had a significant negative impact on the biased technological progress with weak environmental constraints. The increase in R&D intensity was conducive to biased technological progress, while trade openness and capital deepening hindered biased technological progress. Energy production efficiency inhibited biased technological progress without environmental constraints but promoted biased technological progress with weak and strong environmental constraints. To encourage industrial green technological progress, the government should increase the level of subsidies for green technological innovation, improve and enrich environmental constraint tools, and implement phased environmental regulation policies. [ABSTRACT FROM AUTHOR]

To explore the clinical curative effect of transperineal real-time three-dimensional ultrasound evaluation of biofeedback electrical stimulation combine with pelvic floor muscle exercise in the treatment of postpartum pelvic floor dysfunction.96 postpartum pelvic floor dysfunction patients who were admitted to our hospital from September 2020 to September 2022were selected, the patients were divided into two groups according to the random number table method, control group (48 cases) received pelvic floor muscle exercise treatment, study group (48 cases) treated with biofeedback electrical stimulation combined with pelvic floor muscle exercise. Transperineal real-time three-dimensional ultrasound examination before treatment and after treatment, the pelvic floor distress inventory (PFDI-20) scores, pelvic floor dysfunction impact simple questionnaire 7 (PFIQ-7) scores, rest and valsalva action states ultrasound parameters of levator ani muscle were compared between two groups before treatment and after treatment. The correlation between ultrasound parameters of levator ani muscle and PFDI-20 and PFIQ-7 scores were analyzed. The scores ofPFDI-20 and PFIQ-7, the anterior and posterior diameters of levator ani muscle hiatus, left and right diameters of levator ani muscle hiatus and the area of levator ani muscle hiatus at rest and Valsalva action states in two groups after treatment were lower than those before treatment (P<0.05), the thickness of levator ani muscle at rest state was increased compared with that before treatment (P<0.05).The scores of PFDI-20 and PFIQ-7, the anterior and posterior diameters of levator ani muscle hiatus, left and right diameters of levator ani muscle hiatus and the area of levator ani muscle hiatus at rest and Valsalva action states in study group after treatment were lowerthan those in control group (P<0.05), the thickness of levator ani muscle at rest state was greater than that in control group (P<0.05). Theanterior and posterior diameters of levator ani muscle hiatus, left and right diameters of levator ani muscle hiatus and the area of levator ani muscle hiatus at rest and Valsalva action states were positively correlated with PFDI-20 and PFIQ-7 scores (P<0.05), the thickness of levator ani muscle at rest state were negatively correlated with PFDI-20 and PFIQ-7 scores (P<0.05). The size of levator ani muscle hiatus decrease after the treatment of biofeedback electrical stimulation combine with pelvic floor muscle exercise compare with before treatment, the thickness of the levator ani muscle increase compare with before treatment, and it is related to the improvement ofPFDI-20 and PFIQ-7 scores, transperineal real time three-dimensional ultrasound can objectively and effectively evaluate the treatment effect of postpartum pelvic floor dysfunction patients. [ABSTRACT FROM AUTHOR]

Objective To study the factors affecting hospital death in elderly patients with novel coronavirus infection/disease 2019(COVID-19), and to build a risk prediction model. Methods According to the diagnostic criteria of Diagnosis and Treatment Protocol for COVID-19 Infection (Trial 10th Edition). Totally 775 elderly patients (≥60 years old) diagnosed as COVID-19 infection in the emergency department and fever clinic of the First Hospital of Changsha were selected as the research objects. General data and serum biomarkers of patients were collected. After treatment, the patients' data were divided into survival group and hospital death group. Binary Logistic regression was used to screen the independent influencing factors of death, and ROC curve was used to analyze the predictive value of related indicators on hospital death. Results After treatment, 712 patients (91.9%) survived and 63 patients (8.3%) died in hospital. Binary Logistic regression analysis showed that: ≥90 years old [OR=5.065, 95% CI (1.427,17.974)], type 2 diabetes mellitus [OR=3.757, 95% CI (1.649,8.559)], COPD[OR=5.625,95% CI (2.357,13.421)], monocyte ratio [OR=0.908,95% CI (0.857,0.963)], plasma fibringen [OR=1.376,95% CI (1.053,1.800)] and lactate dehydrogenase [OR=1.005,95% CI (1.001,o1.008)] were independent factors of in-hospital death (P＜0.05). The predictive value of diabetes mellitus + COPD + age + monocyte ratio + plasma fibrinogen + lactate dehydrogenase was proved in hospital death from COVID-19 infected patients: the area under the curve(AUC) was 0.883 (95% CI: 0.827,0.940,P＜ 0.001), the critical value ≥0.710 suggested the risk of death in hospital, the specificity was 0.851, the sensitivity was 0.857. Conclusions The hospital mortality of the elderly after COVID-19 infection is higher and closely related to type 2 diabetes, COPD, monocyte ratio, plasma fibrinogen and lactate dehydrogenase. [ABSTRACT FROM AUTHOR]

Objective: To explore the effect of real-time three-dimensional pelvic floor ultrasound on the evaluation of the efficacy of postpartum stress urinary incontinence (SUI) patients and its correlation with urodynamics. Methods: 139 postpartum SUI patients who were admitted to Shijiazhuang People’s Hospital from April 2020 to December 2022 were selected, and all patients received pelvic floor biofeedback electrical stimulation combined with pelvic floor muscle exercise. Real-time three-dimensional pelvic floor ultrasound and urodynamic examination were performed before and after treatment. The differences in real-time three-dimensional pelvic floor ultrasound parameters and urodynamic indicators before and after treatment were compared. The correlation between real-time three-dimensional pelvic floor ultrasound parameters and urodynamic indicators were analyzed by Pearson method. Results: Real-time three-dimensional pelvic floor ultrasound image feature showed that the structure inside the pelvic hiatus became loose, the echo became weak, the connective tissue of pelvic organs became loose, the gap widened, pelvic diaphragm hiatus area, urethral rotation angle, bladder urethra posterior angle, and bladder neck mobility was relatively large before treatment. After treatment, the puborectal muscles on both sides of the pelvic diaphragm hiatus were symmetrical, and the pubic visceral muscles showed banded hyperechogenicity, pelvic diaphragm hiatus area, urethral rotation angle, bladder urethra posterior angle, and bladder neck mobility decreased compared with before treatment. After treatment, the pelvic diaphragm hiatus area, urethral rotation angle, bladder urethra posterior angle, and bladder neck mobility decreased in postpartum SUI patients in resting state and Valsalva state compared with before treatment (P＜0.05), the abdominal pressure leakage point pressure and maximum detrusor muscle pressure increased compared with before treatment (P＜0.05) . The pelvic diaphragm hiatus area, urethral rotation angle, bladder urethra posterior angle, and bladder neck mobility in postpartum SUI patients in resting state and Valsalva state were negatively correlated with maximum detrusor muscle pressure, abdominal pressure leakage point pressure (P＜0.05),and it was not related to maximum bladder capacity and residual urine volume (P＞0.05) . Conclusion: The real-time three-dimensional pelvic floor ultrasound parameters in postpartum SUI patients after the treatment of pelvic floor biofeedback electrical stimulation combine with pelvic floor muscle exercise are lower than those before treatment, which is related to improvement in urodynamics. Real-time three-dimensional pelvic floor ultrasound examination can be used in clinical practice, evaluate the clinical efficacy in postpartum SUI patients, and to guide clinical treatment. [ABSTRACT FROM AUTHOR]

产科分诊是门诊工作的重要环节。随着现代护理的迅速发展，护理模式已由单一的以疾病为中心的功能制护理转变为以患者为中心的整体护理。由于产科门诊工作繁琐而复杂，产科人群又是特殊性的群体，分诊护士的业务水平、内在素质、沟通技巧及分析判断和组织协调能力等对提高产科门诊分诊质量、提升患者的满意度、塑造良好的医院形象有着重要的意义。 [ABSTRACT FROM AUTHOR]

Objective To compare the vertical changes of dentition in patients with class II malocclusion treated by clear aligner and pendulum appliance. Methods Forty patients with class II malocclusion were enrolled. According to the different appliances used in the treatment, 40 cases were divided into two groups : invisible group and pendulum group, with 20 in each. The vertical displacement distance of the first molars ( U6, L6) in maxilla and mandible and the skeletal changes of the mandible were measured by Dolphin Imaging software before and after treatment. Results The difference of displacement distance between maxillary first molar crown and root increased significantly in the invisible group ( P< 0.05). Compared with the pendulum group, the differences of vertical distance of mandible first molars (LDPH), lower facial height (LFH), and the rate of lower faeial height and anterior facial height ( ANS-Me:N-Me) decreased in the invisible group (all P<0.05) . Conclusions Compared with pendulum appliance, clear aligner can better control the vertical change of the dentition of patients with class II malocelusion. When we put the molars toward the middle distance, it can depress the upper and lower molars. There is no significant increase in the mandibular angle and the lower plane, and the 1/3 height increase is relatively small. [ABSTRACT FROM AUTHOR]

BACKGROUND: Microvascular dysfunction is a key factor in the occurrence and development of obesity. Aerobic exercise is not only an effective way to reduce fat and body mass, but also can improve microvascular function in obese people. However, some studies have pointed out that resistance exercise, aerobic combined resistance exercise and high-intensity intermittent exercise can also improve microvascular reactivity in obese people. OBJECTIVE: To summarize the characteristics of microvascular reactivity in obese people and the intervention effects and main mechanisms of different exercise modes on microvascular reactivity in obese people, thereby providing a theoretical basis for improving microcirculation function in obese people. METHODS: CNKI and PubMed were searched for relevant literature published from January 2000 to August 2022 using “obesity, microcirculation, microvessels, capillary, microvascular reactivity, microvascular vasodilatation, microvascular blood flow, exercise, training” as Chinese and English search terms. Finally, 61 articles were included for review. RESULTS AND CONCLUSION: In the resting state, the function of microvascular endothelial cells is impaired in obese people, which leads to the decrease of microvascular reactivity. However, when oxidative stress and inflammation are not obvious in vivo, microvascular reactivity may not change significantly. During exercise, especially in the process of high-intensity exercise, the microvascular reactivity of obese people is significantly decreased, resulting in blood perfusion insufficiency. Aerobic exercise lasting 6-12 weeks, 3-5 times per week, with the exercise intensity of 65%-80% maximal heart rate can effectively improve microvascular reactivity in obese people, but the “dose-response” relationship of aerobic exercise in improving microvascular reactivity in obese people still needs to be further studied. Aerobic exercise combined with resistance exercise lasting 6-12 weeks, 3 times a week, with the exercise intensity of 65%- 80% 1 repetition maximum can effectively improve microvascular reactivity in obese people, but resistance exercise alone requires longer intervention time. High-intensity intermittent exercise lasting 4-12 weeks, 2-3 times per week, with the exercise intensity of maximum aerobic intensity or above can improve microvascular reactivity in obese people. However, due to the lack of relevant studies, further studies are needed to clarify the intervention effect of highintensity intermittent exercise on microvascular reactivity in obese people. Regulating the level of nitric oxide/endothelin-1 and the expression of vascular endothelial growth factor in different tissues may be the main mechanism by which exercise improves microvascular reactivity in obese people. [ABSTRACT FROM AUTHOR]

In order to investigate the effects of different application methods of zinc fertilizer on the zinc content of wheat (Triticum aestivum L.) grains in China, published literature was reviewed and relevant data was collected for analysis. The results show that the main application methods for zinc fertilizer in China were soil, foliar, and soil+foliar application, and the average zinc input of soil application (12.6 kg·hm-2 ) was higher than that of foliar application (1.57 kg·hm-2 ) . The distribution of zinc content in wheat grains without zinc fertilizer ranged from 14.6 mg·kg-1 to 50.0 mg·kg-1, and 95.3% of wheat grains had zinc content <40 mg·kg-1 . The distribution of zinc content in grains after soil+foliar application ranged from 24.0 mg·kg-1 to 70.9 mg·kg-1, and 76.2% of wheat grains had zinc content >40 mg·kg-1 . The average increase rate of zinc content in grains under different application approaches was as follows：soil+foliar application (62.6%) > foliar application (47.2%) > soil application (24.6%) . There was a significant positive correlation between the increase rate of wheat grain zinc content and the amount of exogenous zinc input in soil and foliar application, i.e., when the zinc input increased by 1 kg per hectare, the zinc content in grains increased by 0.74% and 16.39%, respectively. The average utilization efficiency of zinc fertilizer after foliar application (7.27%) was higher than that of soil application (0.59%) and soil+foliar application (0.94%) . Therefore, the zinc content of wheat grains could be increased using different application methods; soil + foliar application was most effective, while foliar application possessed the highest zinc utilization efficiency. [ABSTRACT FROM AUTHOR]

Objectives To explore the experimental approach for in vitro primary culture of chondrocytes of mouse cranial base synchondrosis and to investigate its basic biological features. Methods The spheno-occipital synchondrosis of new natal mouse was harvested through surgical dissection， from which chondrocytes were further isolated through enzymatic digestion with trypsin and type II collagenase. Chondrocytes of the primary and successive generations were cultured with serum containing Dulbeccomodified eagle's medium (DMEM). Optical microscopic imaging， growth curve tracing and immunohistochemistry were conducted to observe the morphological features， growth behavior and type II collagen expression. Results Within five generations，the cultured cells consistently presented typical morphological and functional features of chondrocyte. Conclusion The surgical tissue dissection combined with double enzymatic digestion is a reliable experimental approach for the primary culture of chondrocytes of mouse cranial base snychondrosis. [ABSTRACT FROM AUTHOR]

At present, it is difficult to evaluate the feasibility of the current reservoir dam emergency plan and lack of technical guidance in the evaluation process. From the four dimensions of organization system, operation mechanism, emergency support and emergency training, this paper established the secondary feasibility evaluation index system of reservoir and dam emergency plan. It used analytic hierarchy process and entropy weight method to calculate the principal and objective solid weight of each index and introduced genetic algorithm and variable weight theory to make coupling correction. Combined with cloud model theory, a comprehensive evaluation model for the feasibility of reservoir dam emergency plan was established. The results show that the comprehensive score of the feasibility of the reservoir emergency plan is 85.66, and the evaluation grade is excellent, which is consistent with the evaluation result of the plan. The validity and applicability of the improved method in the feasibility evaluation of reservoir dam emergency plan are verified. [ABSTRACT FROM AUTHOR]

Due to the heterogeneity of the reservoir, the deep high-yield carbonate reservoirs have obvious differences in reservoir types, which often include pores and fractures. In addition, the reservoirs have strong stress sensitivity caused by large burial depth and high-velocity non-Darcy flow caused by high production and flow rate, which brings challenges to well test and reservoir parameter inversion. In this paper, focusing on the deep high-yield carbonate reservoirs, the pseudo-pressure and the skin coefficient were introduced respectively, considering the two characteristics of strong stress sensitivity and high-velocity non-Darcy flow, and the fracture-pore dual medium well test model was established. The mathematical model in the Laplace space was obtained by the transformation, the analytical solution of the bottom hole pressure was obtained, the pressure response model curve was drawn, and the six flow stages of the curve and the sensitivity analysis were defined. The results show that: under the influence of stress sensitivity, the pressure derivative curve moves upward, and the stronger the stress sensitivity is, the greater the upturn of the curve. In addition, the higher the production, the greater the skin factor, the greater the additional pressure drop, and the higher the position of the pressure and pressure derivative curves. Main parameters such as stress sensitivity coefficient 0.027 and high-velocity non-Darcy flow pseudo skin factor 2.61 were obtained by inversion based on the production performance of a tested well in T Oilfield, reflecting that the production before shut-in was relatively large and the reservoir stress sensitive effect was strong. The fitting results of field application further proved the accuracy and practicability of the model. [ABSTRACT FROM AUTHOR]

Bend flow structure plays an important role in the evolution of natural river morphology. In order to further deepen the understanding of circulation structures and turbulence characteristics in the bends. Taking the continuous bend in Huanghuacheng reach of the Three Gorges Reservoir area as the research object, Acoustic Doppler Current Profiler(ADCP) was used to carry out prototype three-dimensional instantaneous velocity measurements. Scale distribution characteristics of bend circulation structures and turbulence structures were further analyzed. Results show the presence of macro- scale channel circulation structures in the Huanghuacheng reach. Due to the influence of local backwater and riverbed topography, measured vertical lines were characterized by full- depth circulation structure or double- circulation structure. Very large-scale turbulence structures still exist in the continuous curved rivers of the reservoir area, but their scale and distribution are greatly affected by the curved circulation structures. [ABSTRACT FROM AUTHOR]

Objective To comapre the clinical effect of invisible MA and double plate appliance in the treatment of children with early skeletal Class II mandibular retrusion malocclusion. Methods We selected 30 children with skeletal Class II mandibular retrusion malocclusion, with an average age of 10.5 years, divided them into invisible MA appliance correction group (group A) and twin-block correction group (group B), 15 cases in each group. The changes of jaw and teeth before (T0) and after (T1) treatment were measured and analyzed. Results Bone indexes：after treatment, there were statistically significant increases in SNB Angle, decrease in ANB Angle, decrease in Wits value, and increase in Pg/OLP of mandibular position in both groups (P < 0.05), while there was no statistically significant difference between the two groups (P > 0.05). After correction, the anterior height ratio of s-Go/N-ME in both groups decreased, while the mandibular plane Angle SN/MP, the anterior lower height ratio and the anterior lower height ratio of ANS/N-ME in both groups increased (P < 0.05), and the differences between the two groups were statistically significant (P < 0.05). Dental properties: U1-SN of the upper incisor decreased, l1-MP of the lower incisor increased, coverage improved, and molar relationship improved after treatment in both groups, all of which were statistically significant (P < 0.05). Only l1-MP Angle was significantly different between the two groups (P < 0.05). Pancherz analysis was used to conclude that the bone effect of group A was greater than that of group B. Conclusions The two kinds of orthodontics can effectively promote the development of mandible and improve the intersagittal deformity of mandible. After the orthodontics, the mandible will rotate clockwise, but the invisible orthodontics rotate less than the double plate orthodontics. The invisible orthodontic device MA can control the axial inclination of the anterior teeth better, and the loss of the anterior anchorage is less, so the orthodontic treatment can obtain better bone effect. [ABSTRACT FROM AUTHOR]

Objective To study the impact of different personality traits on oral health related life quality （OHRQOL） of adult orthodontic patients in early stage of treatment. Methods According to the Eysenck Personality Questionnaire-Revised short Scale for Chinese （EPQ-RSC）， 82 adult orthodontic patients treated with clear aligner were divided into introvert group， middle group， and extravert group. OHIP-14 questionnaires were collected for 3 times: before treatment （T0）， 1 week after bonding （T1）， 1 month after bonding （T2） to compare the influence of different personality traits on oral health-related quality of life （OHRQOL） for adult orthodontic patients in the early stage of treatment. Results The patient's quality of life was affected to some extent by clear aligner treatment， as the OHRQOL score increased， peaking at 1 week of treatment. Introvert group : the period T2 was decreased in psychological discomfort， psychological disability and the total score which had significant difference compared with the period T0 （P < 0.01）； the period T2 was decreased in psychological discomfort and the total score which had significant difference compared with the period T1 （P < 0.01） . Extravert group : compared with each other， only the period T0 and T2 had difference in psychological discomfort （P < 0.05） . Middle group : the scores of all fields varied in different periods，but there was no statistical significance （P > 0.05） . Patients with different personality traits had differences . The period T0: there was a significant difference in psychological discomfort and the total score between introvert group and middle group （P < 0.01） ; compared introvert group with extravert group， there were significant differences in social disability，disability and the total score （P < 0.01） except for psychological disability; there was a significant difference in physical pain， psychological discomfort and disability between middle group and extravert group （P < 0.01） . The period T1: there was a significant difference only in the field of psychological discomfort between introvert group and middle group （P < 0.01）；compared introvert group with extravert group， there were differences in physical pain， disability and the total score （P < 0.05），and the score of the introvert group was significantly higher than that of the extravert group; there was a significant difference only in the field of psychological disability between extravert group and middle group （P < 0.01） . There was no significant difference in psychological discomfort， disability or other fields， among the three groups in T2 period，merely between extravert group and middle group there were significant differences in pain and physiological disorders during this period. Conclusions Clear aligner treatment has impact on the oral health-related quality of life for patients， the impact is related to the personality traits. The treatment has more negative influence for the introvert group on the OHRQOL than the extravert group， mainly in pain and psychological discomfort. [ABSTRACT FROM AUTHOR]

Based on unsteady seepage theory, taking the rapid change process of reservoir level as working condition and considering the nonlinear relationship between permeability coefficient and the matrix suction, the change rule and variation law of unsteady seepage of a typical earth-rock dam was studied and the transient stability against sliding was calculated. The results show that the dam is in the unsteady seepage stale with the change process of water level, so the dam seepage line is a protuberant, bent and changing curve, and the faster the change rale of water level is, the more obviously bending the curve is. In the stage of water rise, the equi-potenlial line of unsteady seepage field offset to the upstream than that of steady seepage field and the corresponding dam seepage gradient is significantly greater. The faster the water level rising rale is, the greater the seepage gradient is. Seepage failure may occur if it exceeds the allowable values. The transient stability safely coefficient is also changing a lot in the unsteady seepage phase. For upstream dam, the slope stability is increased with the higher water. Conversely it is reduced obviously in the dropping stage of water level, and the more decline rale of water level is, the faster the stability decreases, because it has not enough lime to dissipate the excess pore water pressure and the reverse seepage is generated. [ABSTRACT FROM AUTHOR]

The constituents of Dendrobium crystallinum were isolated by silica gel, Sephadex LH-20 column chromatography and reversed-phase semi-HPLC. Their structures were elucidated by analyzing their spectral data and comparing with the' previously reported literatures. Ten compounds were identified as gigantol (1), 3,4'-dihydroxy-5-methoxydi-hydrostilbene (2), 3,4',5- trihydroxy-3-methoxydihydrostilbene (3), dihydroresveratrol (4), angophorol (5), 3',5, 7- trihydroxy-4'-methoxyflavanone (6), 4', 5,7-trihydroxy-6-methoxyflavanone (7), syringaresinol (8), ß-sitosterol (9) , ß-daucosterol (10). All compounds were firstly isolated from this plant except for compounds 2 and 10. [ABSTRACT FROM AUTHOR]

Objective To analyze the effects of self-ligating bracket on enlarging the maxillary alveolar arch and to investigate the the non-extraction treatment programs. Methods All patients were used heat activated basic and precise theory for the orthodontist in order to make a plan fordeveloping nickel-titanium wire， then assessed by occlusalplane analysis method. The maxillary model andcephalometric radiographs were collected and measured before the treatment. The data of the resultswereanalyzed. Results After the treatment， the increase of the width of the dental arch was related to the ∠FMA， crowding degree and canines initial position. The increase of arch length was related to the ∠ANB， crowding degree，malocclusion classification， canines initial position andthe second molar eruption. Conclusion The essential factors include the crowding degree of arch， ∠FMA， ∠ANB， the angle of the anterior teeth，malocclusion classification，canines initial position andthe second molar eruptioncan affect the result of non-extraction quick self-ligating bracket appliance treatment on enlarging the maxillary alveolar. [ABSTRACT FROM AUTHOR]

Objective: To compare the clinical efficacy of video assisted thoracoscopic surgery (VATS) and the levels of micrometastases related factors of esophageal-resection patients. Methods: A total of 60 patients with early esophageal cancer who underwent either a VATS (30) or a thoracotomy (30) were recruited for this study, whose clinical efficacies (operative time, bleeding, complications and hospitalization time) were analyzed. The blood and pleural fluid samples of the participants were taken preoperatively and at post-operatively 24/72h (for pleural lavage) or 3/7 day (for blood) to analyze the CK19/20 mRNA levels in tumor shedding cells by Q-PCR and the protein levels of IL1-β and HMGB1 in blood or pleural fluid samples by ELISA. Results: Compared with the thoracotomy group, patients in the VATS group lost significantly less blood, and got quicker recovery (P<0.05). Both IL1-β and HMGB1 concentrations in blood and chest drainage fluid of patients in VATS group were significantly lower than those in the thoracotomy control group (P<0. 05). No significant difference was found between two groups in the mRNA levels of CK19 and CK20 in chest drainage fluid samples (P>0.05). Conclusion: Compared with the traditional thoracotomy approach, VATS tumor esophagectomy could promote the recovery, and had fewer impact on the micrometastases related factors, which it was worthy of clinical popularization. [ABSTRACT FROM AUTHOR]

目的 探讨鼻咽喉相关内镜手术治疗儿童上气道咳嗽综合征(UACS)的疗效和临床意义.方法 对2014年1月至2017年6月该院确诊为UACS的135例患儿进行鼻咽喉相关内镜检查,对37例上气道存在明显局部病变且有手术指征者实施鼻咽喉相应内镜手术治疗,其中腺样体切除术28例,咽淋巴滤泡消融术3例,舌根淋巴滤泡消融术2例,下鼻甲消融术2例,鼻息肉摘除术1例,鼻内镜功能性手术1例.术后随访6～24个月,分析手术治疗的效果.结果37例存在明显局部病变且有手术指征的UACS 患儿实施鼻咽喉上气道相应内镜手术治疗后痊愈26例(70.27％),好转10例(27.03％),无效1例(2.70％),总有效率为97.30％(36/37).结论 对鼻咽喉明显存在局部病变且具有手术指征的UACS患儿给予相应内镜手术治疗效果显著,值得临床推广应用. [ABSTRACT FROM AUTHOR]