Search

BACKGROUND: Due to the treatment of cervical spondylosis, the Zero-P system of the anterior cervical interbody fusion system will have problems such as screw loosening and fracture after operation, so a novel Low-P system has been developed. OBJECTIVE: To compare the effects of the novel Low-P and Zero-P anterior cervical intervertebral fusion systems on the biomechanical properties of adjacent segments of the cervical spine and to perform stress analysis on the internal fixation system, so as to provide a theoretical reference for clinical treatment. METHODS: A complete model of the C1-C7 segment of the cervical spine was established. Based on the effectiveness of the model, a finite element model of Low-P (type Z Low-P and type H Low-P) and Zero-P system implanted in C4-C5 segments was established. The stress distribution of implanted devices and adjacent vertebral nucleus pulposus, fibrous rings and end plates was analyzed under the conditions of forward flexion, posterior extension, lateral bending and rotation. RESULTS AND CONCLUSION: (1) After implantation of Low-P and Zero-P internal fixation devices, the range of motion of the type H Low-P system was large; the maximum stress value of type Z Low-P system was small; the maximum stress of Zero-P on the nucleus pulposus of adjacent segments was large; the maximum stress of end plate was small. (2) The influence of three internal fixation systems on adjacent segment fiber rings was close. (3) The screw stress of the Zero-P internal fixation system was much greater than that of the Low-P system. (4) It is indicated that compared with Zero-P type internal fixation system, the novel Low-P system reduces the stress value of steel plate and screw, which can reduce screw loosening and internal fixation system failure. The Low-P system has less stress on the nucleus pulposus of adjacent discs and reduces disc degeneration in adjacent segments. This paper provides a theoretical basis for the clinical study of a Low-P type internal fixation system. [ABSTRACT FROM AUTHOR]

Using PEG-6000 and NaCl to simulate drought stress, salt stress and drought-salt combined stress, the germination rate, mean germination time and bud fresh / dry ratio were analyzed, and the adaptability of Anabasis aphylla L. seed germination stage to drought and salt environment was discussed. The results showed that the seeds of A. aphylla L. could withstand drought stress, salt stress and combined drought and salt stress to a certain extent. With the increase of stress, the germination of A. aphylla L. would be delayed or not. The low salt environment (200 mmol/ L NaCl) can promote the water absorption of A. aphylla L. from the environment to maintain the turgor pressure of the buds, so as to ensure the smooth settlement of A. aphylla L. in the arid saline environment. [ABSTRACT FROM AUTHOR]

Objective: To explore the relationship between neutrophil/lymphocyte ratio (NLR), platelet/lymphocyte ratio (PLR) and the treatment effect of iodine 131 (131Ⅰ) thyroidectomy after operation for differentiated thyroid cancer (DTC) and the predictive value of the effect of 131I thyroidectomy after DTC operation. Methods: 150 DTC patients who underwent thyroidectomy and underwent 131Ⅰ thyroidectomy after operation in Xuzhou Hospital Affiliated to Jiangsu University from March 2019 to December 2021 were selected as the study subjects, and the patients were divided into successful thyroidectomy group (107 cases) and unsuccessful thyroidectomy group (43 cases) according to the effect of 131Ⅰ thyroidectomy, neutrophil count, platelet count, lymphocyte count were obtained by blood routine examination and NLR and PLR were calculated, and the NLR and PLR were compared between the two groups. The influencing factors of 131Ⅰ thyroidectomy efficacy was analyzed by single factor and multiple factor logistic regression model, and the predictive value of NLR and PLR on the efficacy of 131Ⅰ thyroidectomy was analyzed by receiver operating characteristic curve (ROC). Results: The NLR and PLR in the successful thyroidectomy group were lower than those in the unsuccessful thyroidectomy group (P＜0.05), single factor analysis showed that the levels of thyroid stimulating hormone (TSH) was higher than that in the unsuccessful thyroidectomy group, thyroglobulin (Tg) in the successful thyroidectomy group was lower than those in the unsuccessful thyroidectomy group, and the maximum diameter of the lesion in the successful thyroidectomy was smaller than that in the unsuccessful thyroidectomy group (P＜0.05) .Multivariate logistics regression analysis showed that, high NLR, PLR and Tg were independent risk factors for failure of 131Ⅰ thyroidectomy (P＜0.05) .The area under ROC curve (AUC) of NLR, PLR and combined detection predicting the efficacy of 131Ⅰ thyroidectomy was 0.760, 0.732, 0.829respectively, and the AUC of NLR and PLR combined detection was higher than that of the two alone. Conclusion: High NLR and PLR are independent risk factors for unsuccessful 131Ⅰ thyroidectomy after DTC operation, and early detection of NLR and PLR levels has good predictive value for the efficacy of 131Ⅰ thyroidectomy after DTC operation. [ABSTRACT FROM AUTHOR]

Objective: To investigate the effect of Xingnao Kaiqiao acupuncture on postpartum depression (PPD). Methods: A total of 80 patients with PPD in our hospital were selected from January 2022 to September 2022 and divided into two groups with 40 cases in each group by random number method. The control group was given conventional Western medicine, and the observation group was treated with acupuncture combined with Western medicine. The course of treatment was eight weeks. The therapeutic efficacy and safety of the two groups were analyzed, and the degree of depression [Hamilton Depression Scale (HAMD), Edinburgh Postpartum Depression Scale (EPDS)], sex hormone levels [progesterone (P), estradiol (E2)], neurotransmitter levels [5-hydroxytryptamine (5-HT), orphanin FQ (OFQ)] were compared between the two groups before treatment and eight weeks after treatment. Results: The efficacy of the observation group was higher than that of the control group, and the difference was statistically significant (P＜0.05). After eight weeks of treatment, the HAMD, EPDS scores and OFQ levels of the two groups decreased compared with those before treatment, and the observation group was lower than the control group; the P, E2 and 5-HT levels of the two groups increased compared with those before treatment, and the observation group was higher than the control group, and the difference was statistically significant (P＜0.05). Conclusions: Xingnao Kaiqiao acupuncture has a significant effect on the treatment of PPD, which can improve the expression of depressed-related factors and reduce the degree of depression with high safety. [ABSTRACT FROM AUTHOR]

Based on the data of land use and land cover change in 2000, 2010 and 2018, the temporal and spatial evolution characteristics of the landscape pattern and ecosystem services in the Hanjiang Eco-Economic Belt were measured, and the impact of the landscape pattern index on ecosystem services was explored by using a geographically weighted regression model. The results showed that: (1) From 2000 to 2018, the landscape pattern of the Hanjiang Eco-Economic Belt changed significantly, the degree of fragmentation and decentralization of each landscape type deepened, and the shape became more complex. (2) The ecosystem service value of the Hanjiang Eco-Economic Belt showed a trend of first increasing and then decreasing, with the overall characteristics of being high in the central and western regions and low in the eastern regions. (3) From 2000 to 2018, the landscape pattern index of the Hanjiang Eco-Economic Belt had a significant impact on ecosystem services, but the impact on different regions was quite different. On the whole, PD, ENN_MN, SPLIT, and SHDI had negative effects on ecosystem service value, while IJI had positive effects on ecosystem service value. The study is helpful to enhance the scientific understanding of the relationship between the landscape pattern and ecosystem services on a county scale and provides a scientific basis for exploring the influencing factors of regional landscape ecological security and implementing ecological protection policies. [ABSTRACT FROM AUTHOR]

Objective To investigate the prognostic risk factors of patients with septic shock based on circulatory and cellular immune effects, to accurately regulate the noradrenaline dose, alleviate immune function suppression, and improve the success rate of septic shock treatment. Methods This is an observational, retrospective, cohort study. According to the inclusion and exculusion criteria, 160 patients with septic shock treated in ICU of the first affiliated hospital of Kunming medical university from May 2021 to December 2022 were collected, and all of them were given standard cluster treatment. At the same time, according to 28d survival outcome in patients with septic shock was divided into death group （n = 89) and survival group （n = 71), statistics of two groups of patients admitted to the hospital within 24h baseline data, test indicators, the weighted average dose of noradrenaline, blood gas index, microcirculation index, cellular immunity and early treatment of clinical data in 72h. Meaningful indicators were identified by single-factor analysis, and a multivariate COX proportional risk regression model was applied to screen out independent risk factors affecting the prognosis of patients with septic shock. Results Multivariate COX regression model analysis results showed that: age （HR = 1.05, 95%CI: 1.09～1.12, P = 0.036), nutritional mode （HR = 0.74, 95%CI: 0.56～0.90, P = 0.037), the weighted average dose of norepinephrine （HR = 6.21, 95%CI: 4.09～9.43, P < 0.001), IL-6 （HR = 1.16, 95%CI: 1.09～1.31, P = 0.012), absolute value of T lymphocytes （HR = 0.47, 95%CI: 0.24～0.91, P = 0.025), mHLA-DR （HR = 0.46, 95%CI: 0.28～0.75, P = 0.002) .Six factors were independent risk factors affecting the outcome of patients with septic shock to visualize the forest plots presented. Conclusions The age, the weighted average dose of norepinephrine and IL-6 are the dangerous factors affecting the prognosis of patients with septic shock. The hazard ratio is greater than 1. Nutrition, T-lymphocyte absolute value and mHLA-DR are the protection factors affecting the prognosis of patients with septic shock. The hazard ratio is less than 1. [ABSTRACT FROM AUTHOR]

多发性硬化(MS)是一种免疫性疾病,主要特点为中枢神经系统慢性炎性脱髓鞘,病变主要累 及白质,且常有新旧病灶并存现象。临床不典型者易误诊为单纯视神经炎、脑卒中、脊髓炎等疾病。该文所报 道的病例主要表现为右侧肢体无力伴言语含混,入院考虑脑梗死急性期,经相关对症治疗后病情未见明显缓 解,后追问病史及完善脑脊液IgG-寡克隆区带后明确诊断为MS,经激素冲击治疗后症状明显缓解。该病例提 示临床工作中遇到以肢体无力为主要症状时,也应警惕MS的可能,更应仔细询问病史,全面完善相关检查,避 免误诊、漏诊。 [ABSTRACT FROM AUTHOR]

为提高对肉毒素中毒的认识, 避免漏诊、误诊. 该文回顾性分析了1例肉毒素中毒误诊为重症肌 无力患者的诊治经验, 结合文献学习和探讨肉毒素的临床应用, 分析该病例误诊原因. 该例患者医源性肉毒素注 射术后, 出现眼睑下垂, 经积极诊疗后眼睑下垂逐渐改善, 后未再出现眼睑下垂. 目前很多临床医生对于肉毒素的 认识不足, 中毒的症状缺乏特异性, 临床医生应详细询问病史, 综合考虑临床资料, 从而降低误诊、漏诊率. [ABSTRACT FROM AUTHOR]

The iron-based amorphous alloy powder was subjected to cyclic cryogenic treatment to enhance the ability of plastic deformation, and coatings were deposited on substrate materials with different hardness, including AZ31B magnesium alloy, 6061 alu minum alloy and Q235 carbon steel. The effect of cryogenic treatment on the cold spray deposition behavior of iron-based amorphous powder on different substrate materials was studied. The interfacial bonding state between coatings and substrate materials, the friction and wear properties of cold sprayed coatings were comprehensively evaluated. Results show that the hardness, thermal conductivity and elastic modulus of the substrate will affect the strain condition, heat dissipation rate and rebound energy of the particles, and then affect the deformation state, compactness and deposition efficiency of the coating. The cryogenic treatment improved the deposition efficiency of amorphous particles, resulting in a great increase of coating thickness. With the increase of hardness of substrate materials, the friction coefficient of substrates and coatings increased, and the wear loss reduced. Compared with the substrate, amorphous alloy particles effectively inhibited the cutting action of the grinding ball, leading to the decrease of the friction coefficient and mass loss of original amorphous coating. Tn comparison, amorphous coatings made of cyro-processed powders had higher density, the friction coefficient curve was more stable and the mass loss was further reduced. The wear mechanism of magnesium alloy matrix and the amorphous coating is abrasive and oxidative wear. The wear mechanism of alu minum alloy matrix is adhesion, fatigue and oxidative wear, while abrasive and oxidative wear are observed in the amorphous coating. The wear mechanism of carbon steel matrix and the amorphous coating is fatigue and oxidative wear. [ABSTRACT FROM AUTHOR]

Rapid urbanization processes alter the regional underlying surface, leading to changes in the hydrological cycle. Such changes have made it difficult to explain the traditional water yielding and runoff routing mechanism, which necessitates our new exploration. In this paper, taking the Yangtze River Delta region as an example, we have conducted the experimental observations in basins with the different urbanization levels and different space scales. Via the collected first- hand hydrologic data, namely, rainfall, soil moisture, and streamflow with high resolutions (5 min time intervals), we adopted data-driven flood feature analysis to reveal the responses of the flood characteristics, such as flood lag time and peak discharge. Then, we discussed the response mechanism of rainstorm and flood in rapid urbanization areas. The main conclusions are as follows: ① Compared with other land use / cover types, the response of soil moisture for urban land are more intense under different rainstorm events ( usually increasing more than 4% for the surface layer) . The change of underlying surface in urbanized area affects the processes of surface runoff by influencing the dynamics of soil moisture. The soil moisture content of urban land and wasteland with low vegetation coverage showed steep rise and fall with the beginning and end of rainfall, while that of land use with higher coverage showed slow rise and decline trends. ② Flood peak lag time and peak discharge are mainly controlled by watershed scale. There have power law relationships between flood lag time and peak flow with watershed scale, and factors such as impervious surface and topography also have some influences on flood characteristics. ③ Rainstorm is a direct driving factor of flood in the Yangtze River Delta region. Rainfall characteristics are strongly correlated with the peak discharge, peak discharge per unit area, and runoff depth, with correlation coefficients above 0. 49, 0. 41 and 0. 78, respectively. In general, the natural geographical characteristics and rainfall are the main factors affecting the flood characteristics, but the impact of the urban underlying surface on the flood characteristics cannot be ignored. The processes of rainstorm floods have been directed affected by the modification of soil moisture dynamics due to urbanization. Under the dual role of urbanization and climate change, the regional flood risk would be intensified in the future. [ABSTRACT FROM AUTHOR]

目的：探讨提升西药房药学服务质量的操作效果。方法：对比我院西药房2019年10月之前与2019年10月 之后的药学服务工作状况, 其中2019年10月之前采用的常规药学管理形式, 而2019年10月之后采用的提升药学服务质 量方式, 比较西药房工作在这两个时间段分别出现的差错事件与病人对于药学服务的满意表现。结果：与2019年10月 之前的工作状况对比而言, 2019年10月之后的西药房工作差错事件发生率明显更低, 而病人对药学服务的满意程度明 显更高, 组间差异值（P < 0.05)。结论：实现增强西药房药学服务质量的各种措施, 能够进一步降低西药房工作出 现差错的几率, 从而确保病人的用药安全, 进而提高药学服务的满意度。 [ABSTRACT FROM AUTHOR]

BACKGROUND: Some patients with cervical spondylotic myelopathy suffer from certain low-energy trauma or only a single hyperextension movement of the neck, and then their neurological symptoms deteriorate, showing typical symptoms of traumatic central cervical syndrome. Although the overall prognosis is good, many patients still have some sequelae. OBJECTIVE: To analyze the risk factors of traumatic central cervical syndrome in patients with cervical spondylotic myelopathy suffering from low-energy trauma, and the correlation with neurological dysfunction. METHODS: Between January 2012 and December 2016, the clinical data of 181 cervical spondylotic myelopathy patients, treated in the First Affiliated Hospital of Soochow University, with a history of low-energy trauma were retrospectively analyzed. According to whether traumatic central cervical syndrome occurred, patients were divided into appearing group (68 cases) and non-appearing group (113 cases). The potential risk factors and their correlations with the neurological function of traumatic central cervical syndrome were analyzed, including patients’ general condition, clinical manifestations and imaging findings. This study was approved by the Medical Ethics Committee of First Affiliated Hospital of Soochow University (approval No. (2021)053). RESULTS AND CONCLUSION: (1) Average age and gender were not statistically significant between the two groups (P > 0.05). However, the incidence of hyperextension injury in appearing group was more than in non-appearing group (P < 0.05). (2) Ratios of axial pain, weakness of proximal lower limb, proprioception dysfunction and hand sensory dysfunction were not statistically significant between the two groups (P > 0.05). Hand muscle weakness, hypermyotonia, tendon hyperreflexia and positive pathological signs in the appearing group were higher than those in the non-appearing group (P < 0.05). (3) The C2-7 Cobb angle of the appearing group was lower than that of the non-appearing group (P < 0.05), and the proportion of instability, rigid/mixed ratio and “anterior-posterior clamp type” in the appearing group were higher than those in the non-appearing group (P < 0.05). Both spinal stenosis and cervical spinal cord compression were higher in the appearing group than those in the non-appearing group (P < 0.05). With higher proportions of maximum canal compromise >50% and maximum spinal cord compression >25%, the maximum canal compromise and maximum spinal cord compression in the appearing group were both greater than those in the non-appearing group (P < 0.05). The ratio, length and grade 2 of intramedullary high signal intensity in appearing group were higher than those in the non-appearing group (P < 0.05). (4) Logistic regression analysis indicated that the possible risk factors for traumatic central cervical syndrome were hyperextension injury, intrinsic hand strength, hypermyotonia, positive pathological signs, poor cervical curvature, spine instability, compression type, compression source, maximum canal compromise, maximum spinal cord compression and intramedullary high signal intensity. (5) The correlation analysis indicated that age, intrinsic hand muscle strength, lower limb muscle tone, pathological signs, cervical curvature, cervical stability, maximum canal compromise, maximum spinal cord compression and intramedullary high signal intensity were significantly negatively correlated with neurological function scores (P < 0.05). [ABSTRACT FROM AUTHOR]

BACKGROUND: Some patients with cervical spondylotic myelopathy suffer from certain low-energy trauma or only a single hyperextension movement of the neck, and then their neurological symptoms deteriorate, showing typical symptoms of traumatic central cervical syndrome. Although the overall prognosis is good, many patients still have some sequelae. OBJECTIVE: To analyze the risk factors of traumatic central cervical syndrome in patients with cervical spondylotic myelopathy suffering from low-energy trauma, and the correlation with neurological dysfunction. METHODS: Between January 2012 and December 2016, the clinical data of 181 cervical spondylotic myelopathy patients, treated in the First Affiliated Hospital of Soochow University, with a history of low-energy trauma were retrospectively analyzed. According to whether traumatic central cervical syndrome occurred, patients were divided into appearing group (68 cases) and non-appearing group (113 cases). The potential risk factors and their correlations with the neurological function of traumatic central cervical syndrome were analyzed, including patients’ general condition, clinical manifestations and imaging findings. This study was approved by the Medical Ethics Committee of First Affiliated Hospital of Soochow University (approval No. (2021)053). RESULTS AND CONCLUSION: (1) Average age and gender were not statistically significant between the two groups (P > 0.05). However, the incidence of hyperextension injury in appearing group was more than in non-appearing group (P < 0.05). (2) Ratios of axial pain, weakness of proximal lower limb, proprioception dysfunction and hand sensory dysfunction were not statistically significant between the two groups (P > 0.05). Hand muscle weakness, hypermyotonia, tendon hyperreflexia and positive pathological signs in the appearing group were higher than those in the non-appearing group (P < 0.05). (3) The C2-7 Cobb angle of the appearing group was lower than that of the non-appearing group (P < 0.05), and the proportion of instability, rigid/mixed ratio and “anterior-posterior clamp type” in the appearing group were higher than those in the non-appearing group (P < 0.05). Both spinal stenosis and cervical spinal cord compression were higher in the appearing group than those in the non-appearing group (P < 0.05). With higher proportions of maximum canal compromise >50% and maximum spinal cord compression >25%, the maximum canal compromise and maximum spinal cord compression in the appearing group were both greater than those in the non-appearing group (P < 0.05). The ratio, length and grade 2 of intramedullary high signal intensity in appearing group were higher than those in the non-appearing group (P < 0.05). (4) Logistic regression analysis indicated that the possible risk factors for traumatic central cervical syndrome were hyperextension injury, intrinsic hand strength, hypermyotonia, positive pathological signs, poor cervical curvature, spine instability, compression type, compression source, maximum canal compromise, maximum spinal cord compression and intramedullary high signal intensity. (5) The correlation analysis indicated that age, intrinsic hand muscle strength, lower limb muscle tone, pathological signs, cervical curvature, cervical stability, maximum canal compromise, maximum spinal cord compression and intramedullary high signal intensity were significantly negatively correlated with neurological function scores (P < 0.05). [ABSTRACT FROM AUTHOR]

Aiming at the problem of inefficient operation of the point-line visual odometry (PL-VO) in the simultaneous location and mapping technology when the environmental texture changes, this paper designed feature extraction adaptive optimizer based on environmental information entropy to improve the efficiency and robustness of the original PL-VO algorithm. The optimizer used image information entropy as the main influencing factor to determine the optimal extraction features of the odometry, and generated a strategy map with included feature extraction options. It could also perform predictive calculations on the unexplored area, and quickly matched it with the strategy map to obtain the best feature extraction strategy for the area. It tested the average processing time and mapping effect of the PL-VO with an optimizer (APL-VO) in the TUM dataset. Experimental results show that APL-VO has stronger robustness and mapping efficiency in a hybrid environment than the original algorithm. [ABSTRACT FROM AUTHOR]

[Objective] The present paper aimed to explore the effects of microbial agents combined with leaf barrier on the translocation and accumulation of Cd in rice, and provided important reference for the safe production of moderate and mild Cd contaminated farmland. [Method] The field experiment was adopted, organosilicon and chelated iron were selected as foliar control agents, combined with microbial agents, and a total of 6 treatments were set up in the field: conventional planting pattern ( CK), spraying on the leaf with organosilicone and EDD HA-Fe ( Y), microbial agents derived from Bacillus amyloliquefaciens and Enterobacter ludwigii as base fertilizer applied separately to soil ( Dl and D2), microbial agents derived from B. amyloliquefaciens and E. ludwigii applied separately to soil, meanwhile spraying on the leaf with organosilicone and EDDHA-Fe ( D1 + Y and D2 + Y) . [Result] ( i) Leaf spraying with organosilicone and EDDHA-Fe significantly reduced the content of Cd in leaves, decreased TF roct-maw , and increased the proportion of Cd in roots by 38. 3%, compared with the control. Foliar fertilizer could effectively prevent the translocation and accumulation of Cd to the shoot of rice. (ii) The two formulations of basal application of microbial agents had different effects on Cd accumulation in rice. Compared with the control, the content of Cd in different parts of rice was decreased by basal application of B. amyloliquefaciens, and t he variation of Cd proportion was small. Applying with E. ludu!igii, Cd content in leaves of rice decreased, and Cd content in stems and grains increased significantly, which were 2. 06 and 1. 17 times higher than those in control, respectively. Meanwhile, the accumulation of Cd in whole plant was increased by 9 . 8 % . ( iii) The accumulation of Cd in rice plants decreased and the distribution of Cd in different parts of rice was significantly changed by basal application of microbial agents combined with foliar fertilizer. When treated with Dl + Y, the proportion of Cd in grains was 1. 68 times higher than that in the control, and the proportion of Cd in roots was 63. 5 % equivalent to the control. The combination of microbial agent in B. amyloliquefaciens and foliar fertilizer could accelerate the translocation of Cd to the shoot and grains of rice. Wben treated with D2 + Y, the TF,root-straw of Cd decreased by 64. 5 % compared with CK, the root Cd content was 1. 57 times higher than that of the control, and the proportion of Cd in the root increased by 57 . 7 % . Cd was restricted to the root by the combination of the basal application of E. ludwigii and foliar fertilizer, so that limited Cd was transferred to the shoot of rice. [Conclusion] The application of B. amyloliquefaciens agents, combined with leaf spraying of organosilicone and EDD HA-Fe can reduce the accumulation of Cd in the root and increase the transfer of Cd to the shoot of rice. Combined application of E. ludwigii and foliar fertilizer can effectively reduce the accumulation of Cd in the straw and grain of rice, which is one of the important measures for the safety production of medium and mild Cd contaminated farmland. [ABSTRACT FROM AUTHOR]

The effect of different reflector packaging materials and different coupling modes with Si-PM on the light output and energy resolution of Ce: GAGG and CsI(Tl) scintillation crystals were studied. The transmittance and decay time of Ce: GAGG and CsI ( Tl) scintillation crystals were compared. The experimental results show that the light collection efficiency of Ce: GAGG and CsI(Tl) scintillation crystals can be improved by optimizing the reflector material and coupling mode. The light output, energy resolution, transmittance and decay time of Ce: GAGG scintillation crystal are better than those of CsI(Tl) scintillation crystal. The test shows that the best energy resolution of 137 Cs radiation source is 4. 89% at 662 keV for the Ce: GAGG crystal sample that encapsulated with TiO2 reflector material and coupled with silicone grease. [ABSTRACT FROM AUTHOR]

Objective: To explore the effects of rosiglitazone (RSG) combined with insulin (INS) on oxidative stress and lipid profile level in diabetic rats. Methods: 30 healthy male Wistar rats were randomly divided into three groups: healthy control group, DM model group and RSG+INS group, with 10 rats in each group. Diabetic rats were induced by streptozotocin (STZ) model. Then, the rats in RSG+INS group were treated with RSG (3 mg/kg/day) via stomach perfusion and INS (2.25U/kg/day) via hypodermic injection, and administered continuously for 8 weeks. The body weight and blood sugar values of each group were recorded 1 time every 2 weeks. After 8 weeks of drug intervention, the levels of serum total cholesterol(TC), triglyceride(TG), low density lipoprotein (LDL), high density lipoprotein(HDL), glycosylated hemoglobin(HbA1c) and the malonaldehyde(MDA) were detected, and the activities of serum superoxide dismutase(SOD) and glutathione (GSH) were detected. The morphological changes of myocardium were analyzed by hematoxylin alkaline Fuchsin Acid (HBFP) staining. Results: RSG combined with INS treatment in diabetic rats resulted in a time-dependent decrease in blood glucos(P all <0.05). After 8 weeks of drug intervention, the levels of serum TC, TG, LDL, HDL and HbA1c of rats in RSG+INS group were significantly lower than those in DM model group (P all <0.05). Compared with the DM model group, the levels of serum MDA of the rats in RSG+INS group were decreased significantly, while the activities of SOD and GSH were increased significantly (P all <0.05). Compared with the DM model group, the myocardial ischemia/oxygenation in the RSG+INS group was lessened. Conclusions: RSG combined with INS can effectively combat oxidative stress in diabetic rats and improve lipid metabolism in diabetic rats, and it has a protective effect on myocardial tissue. [ABSTRACT FROM AUTHOR]

(1) Background--The business of forest right mortgage loan is still facing great practical difficulties. How the government improve the current policy to stimulate the enthusiasm of financial institutions to carry out forest right mortgage loan is a key problem to be solved urgently. (2) Methods--In this paper, the evolutionary game model is used to analyze the choice of forest right mortgage loan strategy of repeated game between local government and financial institutions under the condition of incomplete information. (3) Results--When R--H--T>0 and L-U-C >0, the evolutionary stable strategy (ESS) of the game model is for the government to issue support policies and banks to carry out forest right mortgage loans. At this time, the net income of commercial banks carrying out forest right mortgage loan is higher than the possible risk loss, and the income of local government issuing forest right mortgage loan supporting policies is higher than that not issuing the supporting policies. Both of them can benefit from the introduction of forest rights mortgage support policy. When R--H--T>0 and L--U--C<0, the evolutionary stable strategy (ESS) of the game model is that the government not issuing supporting policies, and banks carrying out forest right mortgage loan. Meanwhile, the net income of commercial banks carrying out forest right mortgage loans is higher than its possible risk loss, but the income of local government issuing the forest right mortgage loan supporting policies is lower than that of not issuing the supporting policies. When R--H--T<0 and L--U--C>0, the evolutionary stable strategy (ESS) of the game model will change from the government supporting policies, the banks carrying out the forest right mortgage loan to the government not issuing the supporting policies and the banks not carrying out the forest right mortgage loan, indicating that the introduction of forest right mortgage loan policy by banks is not only related to their own benefits, but also related to whether commercial banks actively respond to the policies issued by the government. When R--H--T<0 and L--U--C>0, the evolutionary stable strategy (ESS) of the game model is that the government not issuing supporting policies, and banks not carrying out forest right mortgage loan. The results showed that the local government and banks could not obtain incomes from the forest right mortgage loan before they establish a sound forest property mortgage loan system. (4) Conclusions and Discussions--Whether the local government issues forest right mortgage loan support policy has a significant impact on further promoting commercial banks to carry out forest right mortgage loan business. When the non-performing rate of forest right mortgage increases and the net income obtained decreases, the enthusiasm of banks to carry out forest right mortgage will be greatly reduced. Only when the local government issues supporting policies to ensure the safety and liquidity of commercial banks to carry out forest right mortgage, can the willingness of commercial banks to carry out forest right mortgage be enhanced, so as to ensure the evolutionary game system be in equilibrium. In order to encourage more financial institutions to provide forest right mortgage loans, this paper puts forward some policy suggestions, such as perfecting the relevant laws and regulations of forest right mortgage loan, constructing scientific incentive mechanism of forest right mortgage loan, establishing and perfecting the assessment index of forest right mortgage loan and so on. [ABSTRACT FROM AUTHOR]

Objective: To explore the effects of rosiglitazone (RSG) combined with insulin (INS) on oxidative stress and lipid profile level in diabetic rats. Methods: 30 healthy male Wistar rats were randomly divided into three groups: healthy control group, DM model group and RSG+INS group, with 10 rats in each group. Diabetic rats were induced by streptozotocin (STZ) model. Then, the rats in RSG+INS group were treated with RSG (3 mg/kg/day) via stomach perfusion and INS (2.25 U/kg/day) via hypodermic injection, and administered continuously for 8 weeks. The body weight and blood sugar values of each group were recorded 1 time every 2 weeks. After8 weeks of drug intervention, the levels of serum total cholesterol (TC), triglyceride (TG), low density lipoprotein (LDL), high density lipoprotein (HDL), glycosylated hemoglobin (HbA1 c) and the malonaldehyde (MDA) were detected, and the activities of serum superoxide dismutase (SOD) and glutathione (GSH) were detected. The morphological changes of myocardium were analyzed by hematoxylin alkaline Fuchsin Acid (HBFP) staining. Results: RSG combined with INS treatment in diabetic rats resulted in a time-dependent decrease in blood glucos (P all <0.05) . After 8 weeks of drug intervention, the levels of serum TC, TG, LDL, HDL and HbA1 c of rats in RSG+INS group were significantly lower than those in DM model group (P all <0.05) . Compared with the DM model group, the levels of serum MDA of the rats in RSG+INS group were decreased significantly, while the activities of SOD and GSH were increased significantly (P all<0.05). Compared with the DM model group, the myocardial ischemia/oxygenation in the RSG+INS group was lessened. Conclusions:RSG combined with INS can effectively combat oxidative stress in diabetic rats and improve lipid metabolism in diabetic rats, and it has a protective effect on myocardial tissue. Reset [ABSTRACT FROM AUTHOR]

The usage and maximum residue limits (MRLs) for plant growth regulators (PGRs) in foodstuffs are social issues widely concerned by the public and various stakeholders. This paper overviews the latest updates on PGRs in the Chinese national food safety standard, MRLs for pesticides in foods (GB 2763—2019), and conducted a matching analysis with domestic PGR registration and application. Furthermore, the PGR MRLs among China, Codex Alimentarius Commission (CAC), USA, Japan and EU were compared. The main findings and suggestions were given in this review. Firstly, the domestic standard covers almost half (41.7%) registered PGR active ingredients, which surpasses CAC.Secondly, the domestic standard basically contains staple crops, but the product categories and their classification stipulated in the standard are not as rich and detailed as those in EU and Japan. Especially for minor crops and foodstuffs of animal origin. The standard system for PGRs still needs to be further improved. Thirdly, the domestic standard is not aligned to international standards in some extent, and may have less influence on international trade. Finally, suggestions were put forward to improve the MRL standard system of PGRs, such as synchronising the MRL standard with the pesticide registration, and acting on the international convention. [ABSTRACT FROM AUTHOR]

There is a problem of unsatisfactory ear rate in the casting and rolling process of 3003 aluminum alloy. This article takes the cold rolled 1 mm sheet and strip of 3003 aluminum alloy produced by our company as the research object, and uses EBSD detection method to study the relationship between ear rate, annealing temperature, and texture structure during the punching process of 3003 aluminum alloy cold rolled sheet at different annealing temperatures. The key factors affecting ear rate are identified. The research results indicate that the texture in aluminum alloy sheets after cold rolling and annealing of 3003 cast and rolled products is mainly composed of deformation textures such as Copper, Brass, S, Goss, and recrystallization textures such as Cube, CubeND, P, R, and Brass R. With the increase of annealing temperature, the tendency of deformation texture to transform into recrystallization texture increases, and it is significantly accompanied by the decrease of S type texture and R type texture, while the gradual increase of Cube and CubeND type texture. When the ratio of deformation texture to recrystallization texture is within the range of 0. 67 0. 73, the stamping effect is significantly improved and the ear rate effect is ideal. [ABSTRACT FROM AUTHOR]

临床上, 重症肌无力、干燥综合征及类风湿性关节炎重叠综合征非常少见, 且三者合并发病的 病理机制不是十分清楚, 其可能是重症肌无力导致了患者自身机体免疫功能紊乱, 使得机体对于免疫系统疾病 产生易感性, 打破了机体免疫系统的平衡, 从而导致多种自身免疫性疾病的重叠现象。临床工作者对于疾病的 临床症状及伴随症状需要时刻保持警惕, 在发现诸如重症肌无力之类的自身免疫疾病后, 应考虑到引发其他自 身免疫疾病的可能。 [ABSTRACT FROM AUTHOR]

[Objective] Identifying the biological activity of five brassins registered in the ministry of agriculture in China by different methods, so as to give some suggestions about an appropriate dose and an application method for field. [ Method ] The biological activities of five brassins ( 24-epibrassinolide, 28-homobrassinolide, 28-epihomobrassinolide, 22, 23, 24-triepibrassinolide and 14-hydroxylated brassinosteroid) by the methods of Rice Lamina Inclination, Wheat Leaf-unrolling and Elongation of Bean Epicotyl were compared. As a representative of brassins, 24-epibrassinolide was applied to celery and soy bean by spraying on the leaves and irrigating. [ Result] It was effective on comparing the biological activities of five brassins by the methods of Rice Lamina Inclination, Wheat Leaf-unrolling and Elongation of Bean Epicotyl. In the tests of Rice Lamina Inclination and Wheat Leaf-unrolling, 28-homobrassinolide showed the highest biological activity. 24 - epibrassinolide was more active than others in Wheat Leaf-unrolling Test. On the whole, the biological activity of 24-epibrassinolide and 28- homobrassinolide were higher than that of 28-epihomobrassinolide and 22,23,24-triepibrassinolide. 14-hydroxylated brassinosteroid showed a lower biological activity in three tests. When applied 1-10 fLg·L-1 of 24-epibrassinolide by spraying, the height and the shoot biomass of the celery were greater than those in the control groups. The height, root length and shoot biomass of celery treated by spraying with 24-epibrassinolide were significantly higher than those by irrigating. With the treatment of 24-epibrassinolide in the range of 0. 05 - 1. 00 fLg·L-1, applying the 24-epibrassinolide by spraying and irrigating promoted the shoot of soybean. In the range of 0.05 - 1. 00 fLg·L-1, the plant height and shoot biomass of soybean were significantly increased by spraying with a high dose and irrigating with a low dose. [Conclusion] All the three methods can effectively identify the biological activities of five brassins, among which the biological activities of 24-epibrassinolide and 28-homobrassinolide were higher. 24-epibrassinolide was beneficial to the growth of celery and soybean by spraying and irrigating. The effective dose of 24~epibrassinolide to promote crops by irrigating was lower than that by spraying. The dose of brassins should be adjusted according to the biological activity and application method. [ABSTRACT FROM AUTHOR]

BACKGROUND: Bone marrow mesenchymal stem cells have achieved good clinical effect in the treatment of spinal cord injury. However, most of the existing studies focus on the pathophysiological changes, and less is reported on the molecular regulatory mechanism involved. OBJECTIVE: To study the potential molecular targets and signal pathway related to the use of bone marrow mesenchymal stem cells in the treatment of spinal cord injury based on bioinformatics analysis. METHODS: The microarray data of bone marrow mesenchymal stem cells for spinal cord injury treatment were retrieved from GEO database and then mapped to the background network of spinal cord injury obtained from CTD database. Finally, the differentially expressed genes were obtained. A protein-protein interaction network constructed by sting was used to analyze its network characteristics using Cytoscape and obtain the core molecular targets in the process. Finally, the molecular functions and signal pathways of the above molecular targets were analyzed by functional enrichment of the above genes on the website of WebGestalt. RESULTS AND CONCLUSION: According to the data of GEO chip, there are 126 core molecular targets in the treatment of spinal cord injury by bone marrow mesenchymal stem cells, 60 of which have been reported in CTD database. According to the results of sting and Cytoscape, there are 57 nodes in the protein-protein interaction network, among which 10 core targets are MAPK3, tumor necrosis factor, interleukin 6, CASP3, vascular endothelial growth factor A, MAPK1, CCL2, interleukin 1B, proto-oncogene protein, insulin-like growth factor 1. In this process, the main regulatory pathways are interleukin 17, MAPK, tumor necrosis factor, Toll-like receptor and nod-like receptor. The two most important aspects of this process are the inhibition of inflammatory response mediated nerve damage and the nutritional repair of damaged nerve. [ABSTRACT FROM AUTHOR]

BACKGROUND: Open reduction and internal fixation with locking plate is wildly used in treatment of the greater tuberosity fracture, but certain disadvantages still existed. OBJECTIVE: To compare the effects of open reduction and internal fixation with suture anchors and locking plate in the treatment of the greater tuberosity fracture. METHODS: A retrospective review of 33 patients with greater tuberosity fracture treated with open reduction and internal fixation between January 2016 and December 2018 was conducted. According to internal fixation method, the patients were divided into anchor group (n=7) and plate group (n=26), which received open reduction + suture anchor fixation and open reduction + locking plate fixation. Operation time, incision length, intraoperative blood loss, postoperative displacement of fracture mass, and Constant-Murley score 1 and 3 months after surgery and in final follow-up were compared between the two groups. Adverse reactions were recorded in the two groups. RESULTS AND CONCLUSION: (1) Operation time was shorter in the anchor group (73.1±10.5 minutes) than in the plate group (98.2±11.9 minutes). Incision length was shorter in the anchor group (7.3±1.1 cm) than in the plate group (14.9±1.7 cm). Intraoperative blood loss was less in the anchor group (45.0±7.1 mL) than in the plate group (141.0±25.9 mL) (P < 0.05). (2) Postoperative displacement of fracture mass was larger in the anchor group (3.0±1.8 mm) than in the plate group (1.1±2.3 mm) (P < 0.05). (3) There was no significant difference in Constant-Murley score between the two groups 1 and 3 months after surgery and in final follow-up (P > 0.05). (4) All results suggest that compared with locking plate fixation, suture anchor fixation is easier to be operated with small trauma in the treatment of the greater tuberosity fracture. [ABSTRACT FROM AUTHOR]

Objective: To investigate the relationship between the expression of long non-coding RNA (lncRNA) zinc finger DHHC-type containing 8 pseudogene 1(ZDHHC8P1), maternally expressed gene 3(MEG3), taurineup-regulated gene 1(TUG1) and the clinicopathological characteristics and prognosis in gastric cancer. Methods: Paraffin specimens of gastric cancer tissues and adjacent tissues from 83 patients with gastric cancer who underwent surgical resection or endoscopic biopsy were selected from January 2013 to January 2016 collected by the pathology department of our hospital. The expression of ZDHHC8P1, MEG3 and TUG1 in gastric cancer and paracancerous tissues were detected. The relationship between the expression of ZDHHC8P1, MEG3 and TUG1 and the clinicopathological characteristics of gastric cancer were analyzed. All patients were followed up and the relationship between the expression of ZDHHC8P1, MEG3 and TUG1 and the prognosis of patients was analyzed. Results: The expression of ZDHHC8P1 and TUG1 in gastric cancer tissues were higher than those in adjacent tissues (P<0.05) and the expression of MEG3 was lower than that in adjacent tissues (P < 0.05). The expression of ZDHHC8P1 were related to tumor diameter, differentiation degree, invasion depth, TNM stage, lymph node metastasis and distant metastasis (P<0.05). The expression of MEG3 and TUG1 were related to differentiation degree, invasion depth and lymph node metastasis (P<0.05). Kaplan-Meier survival curve analysis showed that the progression-free survival (PFS) and overall survival (OS) rates of patients with high expression of ZDHHC8P1 and TUG1 were lower than those of patients with low expression of ZDHHC8P1 and TUG1 (P<0.05) and the PFS and OS rates of patients with low expression of MEG3 were lower than those of patients with high expression of MEG3 (P<0.05). Cox risk regression analysis showed that lymph node metastasis, high expression of ZDHHC8P1 and TUG1 and low expression of MEG3 were risk factors of gastric cancer patients'poor prognosis (HR=1.613, 1.956, 2.512, -0.824; P＜0.05). Conclusion: ZDHHC8P1, TUG1 are high express in gastric cancer tissues and MEG3 is low express, the expression of ZDHHC8P1, TUG1 and MEG3 are related to the clinicopathological characteristics and prognosis of gastric cancer, which can be used auxiliary indexs for prognosis evaluation of gastric cancer patients. [ABSTRACT FROM AUTHOR]

BACKGROUND: Studies have shown that nucleotide binding oligomerization domain-like receptor protein 3 (NLRP3) inflammasome, interleukin-18, and interleukin-1β levels can induce an inflammatory cascade response to release inflammatory factors, affect metabolic stress, and damage endothelial cells involved in the development and progression of diabetic foot ulcers, which can provide a reference for early infections. OBJECTIVE: To investigate the predictive effect of peripheral blood mononuclear cell NLRP3 inflammasome, interleukin-18 and interleukin-1β levels on early infection after flap repair of diabetic foot ulcers. METHODS: A total of 147 patients with diabetic foot ulcers were selected and divided into infection group and non-infection group according to whether they were infected within 1 week after operation. Logistic regression was used to analyze the relationship between NLRP3 inflammasome, interleukin-18 and interleukin-1β levels in peripheral blood mononuclear cells and early postoperative infections, and to evaluate their predictive values. RESULTS AND CONCLUSION: In 147 patients with diabetic foot ulcers, 35 cases (23.81%) were infected within 1 week after operation, and 47 strains of pathogenic bacteria were isolated, including 25 strains of Gram-positive bacteria (53.19%) and 22 strains of Gram-negative bacteria (46.81%). Univariate analysis showed that Wagner grade, presence of comorbid diabetic nephropathy, operation time, peripheral blood NLRP3 mRNA, Caspase-1 mRNA, ASC mRNA, interleukin-18 and interleukin-1β levels were risk factors for early postoperative infections (all P < 0.05). Multivariate analysis suggested that Wagner grade, NLRP3 mRNA, Caspase-1 mRNA, ASC mRNA, high interleukin-18, interleukin-1β were independent risk factors (all P < 0.05). Receiver operator characteristic curve results showed that the area under the receiver operator characteristic curve of NLRP3 mRNA, Caspase-1 mRNA, ASC mRNA, interleukin-18 and interleukin-1β for early postoperative infections in patients with diabetic foot ulcers was 0.823, 0.705, 0.676, 0.811 and 0.853, respectively, and the area under the curve of combined predictive efficacy was 0.915. To conclude, patients with diabetic foot ulcers are mainly affected by Gram-positive bacteria, and the levels of NLRP3 inflammasome, interleukin-18 and interleukin-1β in peripheral blood mononuclear cells are independent risk factors for early postoperative infections. The combined prediction efficacy of these indicators is better and deserves further in-depth study. [ABSTRACT FROM AUTHOR]

Aiming at the single description and the noise sensitive problems of the LBP, this paper proposed a MSALTP algorithm. The algorithm first enlarged the original images. Secondly, it divided the images into several regions equally and calculated the mean value of the pixels. Then it calculated the deviation between the center and the mean pixel value of each region. Finally, it extracted the ALTP features and used the resulting statistical features histograms to classify the images. Experiments show that the proposed algorithm recognition rates are higher than the current anti-noise algorithms under different noise. [ABSTRACT FROM AUTHOR]

Objective: To explore the behavior characteristics of violent offenders in interpersonal cooperation task and provide a reference for the rehabilitation of offenders. Methods: Totally 38 violent offenders were screened from a prison, and 40 were recruited for the control group. The prisoner's dilemma task and the point estimate task were used to investigate the interpersonal interaction performance of the two groups of subjects. The frequency of cooperation and betrayal, the level of punishment sharing for partner and the emotional performance of the two groups were analyzed. Results: In the prisoner's dilemma game, the violent offender group showed a lower level of cooperation and chose more defection to gain the benefit (P <0. 05). In the point estimation task, the level of punishment sharing for partner was higher in the violent offender group than in the control group (P<0. 05). The violent offenders also reported more sense of responsibility and guilt, but the difference between the two groups was not statistically significant (P>0.05). Conclusion: This study suggests that violent offenders may share the punishment for their peers and show a certain degree of cooperation when they feel guilty. [ABSTRACT FROM AUTHOR]

[Objective] The study aimed to reveal soil bacteria diversity of Salvia miltiorrhiza continuous cropping soil in Zhongjiang county of Sichuan province. [Method]The rhizospheric and non-rhizospheric soil samples of both siek S. miltiorrhiza Bge and normal S. miltiorrhiza Bge were picked, and soil bacterial communities were analyzed by dilution plate method and PCR-DGGE. [Result]The results showed that a total of 46 bacterial strains were isolated and purified, and 16S rDNA PCR-RFLP analysis showed that there were seven genetic groups formed at the similarity of 79 % . 16S rDNA sequencing analysis of the representative bacterial isolates showed that these strains belonged to genus Bacillus, Brevibacterium, Beijerinckia and Pseudomonas. [ Conclusion ] PCR-DGGE analysis suggested that S. miltiorrhizae continuous cropping changed soil bacterial groups significantly; The genetic diversity of the bacteria groups existed among the tested soil samples; And the sequences of cloned PCR-DGGE bands indicated that most strains were uncultured bacteria. [ABSTRACT FROM AUTHOR]

There was a 61-year-old male patient with cutaneous metastatic lung adenocarcinoma inoculated along a thoracic drainage tube treated in Zhongshan Hospital, Fudan University. The duration of disease was over 2 weeks. The skin lesions were extensive and appeared as purplish red nodules ranging in size from mung bean to small walnut. The nodules were tough and solid, smooth in surface, with infiltration while without ulceration, pruritus or tenderness. The patient developed chest tightness and pain without obvious causes, dull pain in nature and less white sputum 6 weeks before the eruption, and then was diagnosed as malignant tumors of the left lung (poorly differentiated adenocarcinoma), cT1cN3M1c stage Ⅳ B (pleura, bone). Gene tests showed that epidermal growth factor receptor(EGFR)21 exon point mutation L858r，Ros1(-), anaplastic lymphoma kinase (ALK)(-), and physical status score (PS) of 0. The treatment was Dactinib 45mg once each day, supplemented the bone preservation therapy by ibandronic acid. As the patient's condition did not significantly improve and skin nodules increased, also the abdominal B-ultrasound examination showed that multiple metastases in liver, the treatment was changed to Ectinib hydrochloride tablets (Kemena) of 125 mg 3 times a day, combined with Crizotinib capsules (Secor) of 200 mg twice a day. Unfortunately, the patient has now been lost to follow-up. [ABSTRACT FROM AUTHOR]

In this case report a 49-year-old male patient with disseminated lesions such as a large nodule and lots of small peanut-like papules without itching for 9-year history relapsed for 2 weeks. At his first clinical trial of 9 years before，he was treated by the local injection of“Diprospan”and the therapy of psoralen ultraviolet A for 5 times without good result. In case of a limited or asymptomatic disease，a“waitand-see strategy”is recommended and the multiple biopsies were necessary to differentiated from the possibility of the development of a primary cutaneous anaplastic large cell lymphoma. [ABSTRACT FROM AUTHOR]

Hydrus-1D software was used to simulate the joint influences of groundwater and aridity index on the transpiration of Salix psammophila based on field investigation, laboratory test and in-situ test. The results showed that the transpiration receives joint influence from the groundwater and aridity index. The transpiration is mainly controlled by groundwater when the water table depth is 1.0-2.0 m, and controlled by groundwater and aridity index when the water table depth is 2.0-2.5 m, but only controlled by aridity index when the water table depth is more than 2.5 m. The monoexponential decay function can fit the cave between the groundwater and Ta/Tp, whose correlation coefficient is above 0.99. On this basis, the critical water table depths are determined in normal, low and high flow year. The critical water table depths vary in different hydrological years and the vegetation will suffer from water stress when the water table depth is more than 1.24 m(average), and degenerate when the water table depth is more than 2.06 m(average). Meanwhile, the effects of the decline in the water table caused by coal mining on the transpiration of typical vegetation is limited. The decline in the water table caused by coal mining has effect on vegetation when the initial premining water table depth is less than 2.5 m. However, there has little effect on vegetation when the initial pre-mining water table depth is more than 2.5 m, the transpiration is only controlled by climate change at this moment. At present, the main factor that affects the vegetation coverage is climate change(precipitation)because the initial pre-mining water table depth is generally greater than 2.5 m in Yushen mining area. Therefore, the vegetation coverage increases although the water level decreases obviously considering the increasing trend of precipitation in recent years. [ABSTRACT FROM AUTHOR]

Ｔｈｅ ｓｏｌｕｔｉｏｎ ｏｆ ａｎ ｉｎｆｉｎｉｔｅ ｐｌａｎｅ ｃｏｎｔａｉｎｉｎｇ ａ ｃｒａｃｋ ａｎｄ ａｎ ａｒｂｉｔｒａｒｉｌｙ ｏｒｉｅｎｔｅｄ ｉｎｈｏ⁃ ｍｏｇｅｎｅｉｔｙ ｕｎｄｅｒ ｕｎｉａｘｉａｌ ｔｅｎｓｉｌｅ ｌｏａｄ ｗａｓ ｐｒｅｓｅｎｔｅｄ ｂａｓｅｄ ｏｎ ｔｈｅ ｄｉｓｔｒｉｂｕｔｅｄ ｄｉｓｌｏｃａｔｉｏｎ ｔｅｃｈ⁃ ｎｉｑｕｅ． Ｔｈｅ ｓｔｒｅｓｓ ｆｉｅｌｄ ａｎｄ ｔｈｅ ｓｔｒａｉｎ ｅｎｅｒｇｙ ｄｅｎｓｉｔｙ ｗｅｒｅ ｏｂｔａｉｎｅｄ． Ｔｈｅ ｃｒａｃｋ ｐｒｏｐａｇａｔｉｏｎ ｄｉｒｅｃ⁃ ｔｉｏｎ ｗａｓ ｐｒｅｄｉｃｔｅｄ ａｃｃｏｒｄｉｎｇ ｔｏ ｔｈｅ ｍｉｎｉｍｕｍ ｓｔｒａｉｎ ｅｎｅｒｇｙ ｄｅｎｓｉｔｙ ｃｒｉｔｅｒｉｏｎ． Ｔｈｅ ｒｅｓｕｌｔｓ ｓｈｏｗ ｔｈａｔ， ｔｈｅ ｓｏｆｔ ｉｎｈｏｍｏｇｅｎｅｉｔｙ ｈａｓ ａｎ ａｍｐｌｉｆｙｉｎｇ ｅｆｆｅｃｔ ｏｎ ｔｈｅ ｓｔｒｅｓｓ ｉｎｔｅｎｓｉｔｙ ｆａｃｔｏｒ， ｔｈｅ ｓｔｒａｉｎ ｅｎｅｒｇｙ ｄｅｎｓｉｔｙ ａｎｄ ｔｈｅ ｓｔｒｅｓｓ ｆｉｅｌｄ ｎｅａｒ ｔｈｅ ｃｒａｃｋ ｔｉｐ， ｗｈｉｌｅ ｔｈｅ ｈａｒｄ ｉｎｈｏｍｏｇｅｎｅｉｔｙ ｈａｓ ａ ｓｈｉｅｌ⁃ ｄｉｎｇ ｅｆｆｅｃｔ． Ｔｈｅ ｅｆｆｅｃｔ ｏｆ ｔｈｅ ｉｎｈｏｍｏｇｅｎｅｉｔｙ ｏｎ ｔｈｅ ｃｒａｃｋ ｐｒｏｐａｇａｔｉｏｎ ｄｉｒｅｃｔｉｏｎ ｉｎｃｒｅａｓｅｓ ｗｉｔｈ ｔｈｅ ｄｅｃｒｅａｓｉｎｇ ｄｉｓｔａｎｃｅ， ｔｈｅ ｉｎｃｒｅａｓｉｎｇ ａｂｓｏｌｕｔｅ ｖａｌｕｅ ｏｆ ｌｇ（μ２ ／ μ１） ， ａｎｄ ｔｈｅ ｉｎｃｒｅａｓｉｎｇ ｉｎｈｏｍｏ⁃ ｇｅｎｅｉｔｙ ｒａｄｉｕｓ． Ｔｈｅ ｉｎｈｏｍｏｇｅｎｅｉｔｙ ｈａｓ ａ ｌｉｔｔｌｅ ｅｆｆｅｃｔ ｏｎ ｔｈｅ ｃｒａｃｋ ｐｒｏｐａｇａｔｉｏｎ ｄｉｒｅｃｔｉｏｎ ｆｏｒ － ３０° ＜ θ ＜ ３０°． Ｔｈｅ ｓｏｆｔ ｉｎｈｏｍｏｇｅｎｅｉｔｙ ｈａｓ ａｎ ａｔｔｒａｃｔｉｎｇ ｅｆｆｅｃｔ， ｗｈｉｌｅ ｔｈｅ ｈａｒｄ ｉｎｈｏｍｏｇｅｎｅｉｔｙ ｈａｓ ａ ｒｅｐｕｌｓｉｎｇ ｅｆｆｅｃｔ ｏｎ ｔｈｅ ｃｒａｃｋ ｐｒｏｐａｇａｔｉｏｎ ｆｏｒ － ９０° ＜ θ ＜ － ３０° ａｎｄ ３０° ＜ θ ＜ ９０°． [ABSTRACT FROM AUTHOR]

This paper researched image matching issue and proposed a feature point matching algorithm to improve the BRIEF algorithm. The proposed algorithm generated the feature point description operator according to the difference signs and the difference magnitudes relation between the random point and the feature point. BRIEF was sensitive to noise because the small difference magnitude was more susceptible to the noise. To solve this problem, this paper determined a small pixel difference threshold by the neighborhood mean value of the BRIEF. Comparing the Hamming distance between descriptions realized the feature points matching. Compared with BRIEF and ORB algorithm, the experiments prove that the operator has higher discriminant, simple calculation and good noise suppression performance. And the matching accuracy is higher. [ABSTRACT FROM AUTHOR]

The superhydrophilic polymer coating was fabricated by using the sol-gel method and introducing silica nanoparticles into modified PAMAM. The characterization was conducted through FT-IR, SEM, AFM and polymer surface tensiometer to investigate the wettability of the modified PAMAM polymer and structure characteristics of the surface. Moreover, the ice prevention performance was studied. The results showed that the modified PAMAM polymer coating had the micro-nano composite structure and the static contact angle was 9.4°, which reached at superhydrophilic state. Super hydrophilic coating based on modified PAMAM displayed favourable anti-icing characteristics owing to amino and molecular cavity of PAMAM, which contributed to form water film on superhydrophilic surface to suppress icing process. At temperature of-5 °C, the quantity of ice was only 1. 19 g within 40 min, and icing delay time reached to 133 swhile that of the hydrophobic coating was only 38 s. The ice adhesion force of ice on the surface was about 0.33 N, which was significantly better than that of ordinary hydrophilic and hydrophobic coatings. For the test of stability, the average variation rate of the static contact angle and the surface adhesion force of ice on the surface was 1.4%and 1.2%, respectively. [ABSTRACT FROM AUTHOR]

Fungal strains capable of degrading oxytetracycline, norfloxacin and sulfadiazine were screened from the soil contaminated by heavy metals. The strains were enriched and domesticated in medium with the antibiotics as the sole carbon source. After isolation and purification of antibiotic-resistant fungi, and the purified strains were returned to the liquid medium with antibiotics as the sole carbon source. Then used high-performance chromatography（HPLC）and UV spectrophotometry to detect the antibiotic degradation ability of each strains, and those strains were identified by morphological characteristics, the ITS DNA sequence determination and phylogenetic analysis. Four strains of antibiotic-degrading fungi named KS248, KS256, KS257, and KS272 were screened and identified as Fusarium verticillioides, Fusarium solani, Aspergillus sydowii, and Penicillium janthinellum. Among them, strains KS248, KS256, and KS257 had the ability to degrade oxytetracycline, norfloxacin, and sulfamethazine; strain KS272 had the ability to degrade oxytetracycline and norfloxacin. Under antibiotic content of each antibiotic was 1500 μg·L-1, 30 ℃, 150 r·min-1, after 7 days dark culture, the strain KS272 had the strongest ability to degrade oxytetracycline and norfloxacin with the degradation rates of 40.29% and 10.49% respectively; The strain KS256 had the strongest ability to degrade sulfamethazine and the degradation rate was 18.53%. The strains had the ability to degrade two or more antibiotics. The ability of strains to degrade antibiotics from the highest to the lowest was oxytetracycline, norfloxacin, and sulfamethazine. As the concentration of antibiotics increased, the ability of the strains to degrade each antibiotic was weakened. [ABSTRACT FROM AUTHOR]

Objective: To explore the decision-making traits of psychopathic traits offenders under different tasks. Methods: Totally 364 prisoners in a prison were selected, and finally 58 prisoners were enrolled. Psychopathic group contained 28 subjects selected with the Psychopathy Checklist-Revised (PCL-R, PCL-R score ≥25), and control group contained 30 subjects( PCL-R score ≤15). By the cup task and prisoner's dilemma task, the traits of decision-making in the psychopathic subjects were investigated. The rates of risk and security choice of different situations, and frequency of cooperation and defection in the task were analyzed. Results: In the cup task, psychopathic subjects chose more risky options [ F (1,56) =4. 92, P < 0. 05]. There was an interaction effect between group and the level of expected value [ F (1,56) =3. 51, P < 0. 05], which indicated that psychopathic group was more risky than control group at the risk of disadvantage level. In the prisoner's dilemma game, psychopathic group was more likely to choose to defect than control group (P < 0. 05). Even under the premise of peer cooperation, they were more inclined to choose the betrayal and gain greater benefits (P <0. 05). Conclusion: Psychopathic traits offenders tend to gain more benefits regardless of potential risk and betray to pursuit benefits without considering cooperation with their peers, which suggests that psychopathic traits offenders have deficits in both individual and interpersonal decision-making. [ABSTRACT FROM AUTHOR]

The problem of large block percentage ratio of blasting has always affected the production benefit of mine. The implementation of large block percentage ratio of blasting predication based on ensemble learning in machine learning is studied. Firstly， 36 groups of measured data collected from Wushan Copper Mine in Manzhouli are utilized as an example， and 10 kinds of characteristic data are sorted out. Then， the model is trained and tuned by cyclic training of the given parameters， and then the method of cross-validation grid search is used to perform secondary tuning， and the effect of the model after tuning is compared with random forest method， XGBoost model， LightGBM model， and CatBoost model. The results show that the prediction effect of CatBoost model， after two rounds of tuning， is significantly higher than that of other models. The precision rate 98.83% reaches， which proves that CatBoost model has a high prediction level after two rounds of tuning. At the same time， the feasibility of this method in the study of large block percentage ratio of blasting prediction is proved， which provides a reliable reference for blasting parameter design and large block percentage ratio of blasting optimization analysis. [ABSTRACT FROM AUTHOR]

Objective: To investigate the relationship between the expression of centromeric protein F (CENPF) and Krüppel-like factor 4 (KLF4) and epithelial-mesenchymal transformation (EMT) and prognosis in non-small cell lung cancer (NSCLC) tissue. Methods:Cancer tissue samples and paracancer tissue samples 5 cm away from carcinoma tissue of 120 NSCLC patients who underwent surgical resection in Taizhou Fourth People’s Hospital from January 2017 to December 2019 were selected. The positive expressions rate and amount of CENPF, KLF4 and ETM-related markers [E-cadherin and Vimentin] in cancer tissue and paracancer tissue were detected by immunohistochemistry and Western blotting methods. Pearson test was used to analyze the correlation between CENPF, KLF4 and EMT-related markers, and the relationship between the expression of CENPF and KLF4 and the prognosis of NSCLC patients were analyzed. Results: The positive expression rates of CENPF and Vimentin in the NSCLC cancer tissue were significantly higher than those in paracancer tissue (all P＜0.05）, while the positive expression rates of KLF4 and E-cadherin were significantly lower than those in the paracancer tissue (all P＜0.05）. CENPF in the NSCLC cancer tissue was negatively correlated with E-cadherin, and positively correlated with Vimentin (P＜0.05）. KLF4 was positively correlated with E-cadherin, and negatively correlated with Vimentin (P＜0.05）. The positive expressions rate of CENPF and KLF4 in NSCLC cancer tissue were associated with TNM staging and lymph node metastasis (all P＜0.05). The 3-year disease-free survival rate (DFS) of enrolled patients was 60.00%. The 3-year DFS of NSCLC patients CENPF positive expression were significantly lower than those with CENPF negative expression patients (56.25% vs 75.00%, P=0.014) . The 3-year DFS of NSCLC patients with KLF4 positive expression were significantly higher than those with KLF4 negative expression (68.75% vs 54.17%,P=0.048）. Conclusion: The high expression of CENPF and low expression of KLF4 can promote the occurrence and progression of EMT in NSCLC, and lead to poor prognosis of patients. CENPF and KLF4 can assist in predicting the prognosis of patients with NSCLC. [ABSTRACT FROM AUTHOR]

The carbon emission models of engineering refurbished tire were constructed based on life cycle analysis, and the theoretic calculation model and the calculation method of carbon emission were proposed for four stages of engineering refurbished tire with production, transportation, usage and recycle. The carbon emission evaluation indexes of pure carbon surplus, carbon subduction model and carbon subduction rate of engineering refurbished tire were given, and the carbon emission lists at production, transportation and usage stages of engineering refurbished tire were quantitatively analyzed. The carbon emission-subduction lists of five recycling stages of second refurbishment, combustion decomposition, mechanical smash, power generation by combustion and low temperature smash were analyzed, and the comparing analysis and evaluation of carbon emissions at different stages were performed. The results show that the carbon emission of engineering refurbished tire is maximal at production stage and is minimal at transporting stage. The carbon emission subduction efficiency of second retreading is the best, while those of combustion decomposition and low temperature smash are the worst. [ABSTRACT FROM AUTHOR]

Corm rot is the most serious disease on saffron, a Chinese medical herb belonging to "New Zhe Ba Wei". The sensitivity of 82 isolates of the pathogenic Fusarium oxysporum to a novel sterol demethylase inhibitor (DMI) mefentrifluconazole was determined using the mycelial growth rate method and the effects of mefentrifluconazole on the growth, sporulation, spore germination, and cell membrane permeability of F. oxysporum were investigated. The most and least sensitive strains in the population were used to determine the biological activity of mefentrifluconazole against F. oxysporum and the protective and curative efficacy were determined. The results showed that the EC50 values of mefentrifluconazole inhibiting mycelial growth of F. oxysporum ranged from 0.182 μg/mL to 2.491 μg/mL, and the average EC50 value was (0.838 ± 0.438) μg/mL. The sensitivity frequency distributionconforms to normal distribution. Mefentrifluconazole significantly decreased mycelial growth and sporulation of F. oxysporum. The conductivity test of mycelia demonstrated that mefentrifluconazole damaged cell membrane of F. oxysporum resulting in electrolyte leakage. In addition, the protective efficacy of mefentrifluconazole against saffron corm rot was superior to the curative efficacy. These results provide a theoretical basis for the effective control of saffron corm rot in production. [ABSTRACT FROM AUTHOR]

Objective To investigate the effects of miR^l49a on cell proliferation, migration and invasion of esophageal squamous-cell carcinoma cell line Eca-109 and its mechanism. Methods Eca-109 cells were divided into the miR- 449a group and the negative control (NC) group，in which miR449a mimics and NC-mimics were transfected into Eca-109 cells, respectively. Real-time fluorescent quantitative PCR was performed to detect the relative expression of miR^l49a in Eca-109 cells. When the expression of miR449a in Eca-109 cells of the miR449a group was higher than that of the NC group, indicating Eca-109 cell models with up-regulated miR^l49a expression were successfully established. The cell proliferation abilities of the two groups were analyzed by CCK-8 and colony formation assay, which were shown in OD values and cell survival numbers at 12, 24 and 48 h. The cell migration and invasion was measured by Scratch test and Transwell invasion testing system, respectively. Additionally, flow cytometry was performed to detect cell cycle. Real-time fluorescent quantitative PCR and Western blotting were performed to detect the expression of E2F3 mRNA and protein in the two groups. Results At 12, 24 and 48 h, the OD value, the number of survival cells, distance between cells and the number of cells invading into the lower chamber of the miR^l49a group were lower than those in the NC group ( P < 0. 05 or P < 0. 01) . The percentage of cells in G2 phase of the miR^l49a group was higher than that in the NC group, and the percentage of cells in S phase was lower than that of the NC group ( all P < 0. 05 ) . However, there was no significant difference in the percentage of cells in G2/M phase between the two groups (P > 0. 05 ). The relative expression of E2F3 mRNA and protein in the miR^l49a group was lower than that in the NC group ( all P < 0. 01) . Conclusion miR-449a can inhibit the proliferation, migration and invasion of esophageal squamous-cell carcinoma cell line Eca-109 by inhibiting the expression of target gene E2F3. [ABSTRACT FROM AUTHOR]

Objective To investigate the clinical effect of early bowel-relaxing treatment and drainage in the treatment of severe acute pancreatitis (SAP). MethodsA retrospective analysis was performed for the clinical data of 52 patients with SAP who were admitted to Department of Hepatopancreatobiliary Surgery, Zhuzhou Central Hospital, from January 2009 to January 2015, and these patients were divided into conventional treatment group with 22 patients and early bowel-relaxing/drainage group with 30 patients. The incidence of multiple organ dysfunction syndrome and abdominal compartment syndrome within 2 weeks, time to intra-abdominal pressure reduced to below 15 cm H2O, time to gastrointestinal function recovery, pancreatic infection rate, and mortality rate were compared between the two groups. The independent samples t-test was used for comparison of continuous data between the two groups, and the chi-square test was used for comparison of categorical data. ResultsCompared with the conventional treatment group, the early bowel-relaxing/drainage group had significant reductions in the incidence rates of multiple organ dysfunction syndrome (31.8% vs 10.0%, χ2=3.89, P=0.049) and abdominal compartment syndrome (22.7% vs 3.3%, χ2=4.68, P=0.031) within 2 weeks, pancreatic infection rate (40.9% vs 13.3%, χ2=5.15, P=0.023), and mortality rate (22.7% vs 3.3%, χ2=4.68, P=0.031). Compared with the conventional treatment group, the early bowel-relaxing/drainage group had significantly shortened time to intra-abdominal pressure reduced to below 15 cm H2O, time to bowel sound recovery, and time to the recovery of passing of flatus and defecation (t=1.02, 6.67, and 2.13, all P＜0.01). ConclusionIn the early stage of SAP, bowel-relaxing treatment and drainage can effectively reduce intra-abdominal hypertension, protect vital organ function, alleviate the condition of SAP, reduce the incidence of complications, and thus significantly improve the prognosis of SAP. [ABSTRACT FROM AUTHOR]

The preconditioning technique was applied to modify the existent LU-SGS solver for compressible flows,which was unsuitable for the prediction of low-speed incompressible flows. The preconditioning modification included treatment of the eigen system of the governing equations,improvement of the implicit solving method and discretization of the convection terms with the low-diffusion difference scheme and the AU SM+-up scheme. The modified solver was applied to numerical simulations of inviscid bump flows,lid-driven square cavity viscous flows and Laval nozzle flows. The comparison between the present results and those in the previous literatures proves the feasibility of the preconditioning-modified numerical method in the simulation of arbitrary Mach number flows,including the low-speed,the subsonic,the transonic and the supersonic invicid or viscous flows. [ABSTRACT FROM AUTHOR]

Glaucocalyxin A (GLA) is a kind of diterpenoid enantiomers with organic chemical structure of en-１５-oxo-１６- kaurene. It has various pharmacological activities, such as cardiovascular and endothelium cellular protection, anti-blood coagulation, anti-Hepatitis B Virus (HBV), anti-tumor, anti-bacteria, anti-inflammation, hypoxic tolerance, immunomodulation and Ca2+ concentration regulation effect, where as its in vivo safety is quite good. As a folk medicine, it is conventionally used to treat hepatitis, gastritis, mastitis, stomachache and arthralgia. It is also used for ischemic and/or hypoxic cardio-cerebrovascular diseases such as coronary heart diseases, stenocardia and chronic cerebral circulation insufficiency in clinic. This review gives a summary of the pharmacological effects, biological mechanism, and toxicity of Glaucocalyxin A. [ABSTRACT FROM AUTHOR]

The intake of ice crystals by an aero-engine is prone to internal icing, causing loss of engine thrust and, in serious cases, aviation accidents. The numerical simulation of ice crystal icing is an important tool to study ice crystal icing, and the calculation of the collection coefficient is a key part of the numerical simulation of ice crystal icing. Based on the NNWICE platform, the numerical simulation and calculation of the drag coefficient, motion trajectory and collection coefficient of ice crystal icing in the early stage of ice crystal icing is carried out, and the accurate calculation of ice crystal collection coefficient based on Monte Carlo method is achieved. Therefore, the coupled numerical calculation method of ice crystal particle motion and heat and mass transfer under Lagrangian framework is developed；by completing the relevant calculation cases of two-dimensional NACA0012 airfoil, the effects of different drag models and ice crystal phase transition on the impact collection coefficient are compared and analyzed. The results show that the drag model has a little effect on the ice crystal collection coefficient, while the ice crystal phase transition will have a significant effect on the ice crystal motion trajectory and collection coefficient, which lays the foundation for further development of the numerical simulation calculation method of ice crystal icing. [ABSTRACT FROM AUTHOR]

Using non-rhizospheric and rhizospheric soil of sick and normal growing Salvia miltiorrhiza as materials, the soil physicochemical properties and soil fungal diversity was determined. The result showed that, compared with the normal growth of Salvia miltiorrhiza, the organic matter content, total nitrogen, alkali-hydrolysis nitrogen, available phosphorus and available potassium content of was decreased by 60%, 52%, 18%, 18% and 45% in the soil of sick Salvia miltiorrhiza. PCR-DGGE analysis showed that the fungal groups in rhizospheric and non-rhizospheric soil of sick Salvia miltiorrhiza were significant differences. Sequencing results of representative cloned DGGE bands showed that the predominant groups belonged to Acremonium sclerotigenum, Phoma sp., Phialocephala fortinii and Chaetomium sp.. The results suggested that soil fertility decrease and pathogenic fungi increase leads to the continuous cropping obstacle of Salvia miltiorrhiza. [ABSTRACT FROM AUTHOR]

Objective To explore the expression and role of stimulator of interferon gene (STING)-TANK-binding kinase 1 (TBK1)-interferon regulatory factor 3 (IRF3) signaling pathway in the brain of chronic stress mice. Methods Mice were divided into control (CON) group and chronic restraint stress (RST) group. Mice in the RST group were given chronic restraint stress stimulation (6 hours per day, 14 days). After 14 days, the mRNA expressions of pro-inflammatory cytokines CCL2, CXCL10, IL-1β, IL-6, IL-10, and TNFα in the brain were detected and analyzed by qRT-PCR; protein expression of STING, TBK1, p-TBK1, IRF3, and p-IRF3 were detected and analyzed by immunofluorescence staining and Western blotting. Results Compared to the CON group, the mRNA expressions of pro-inflammatory cytokines in the RST group were significantly increased (P<0.05). STING and microglia marker Iba-1 were highly co-located and the expression of STING was decreased as detected by immunofluorescence staining. Moreover, the protein expressions of STING, p-TBK1, and p-IRF3 were significantly decreased (all P<0.01). Conclusion Chronic restraint stress triggers a neuroinflammatory response and the STING-TBK1-IRF3 pathway in the brain of the RST mice is significantly inhibited. [ABSTRACT FROM AUTHOR]

Polder refers to the field where embankments are built around low-lying land to prevent the free flow of external water. The basic geographical unit can also be formed in the river network area of the southern plain in south China. The hydrological process is very complicated, because the interior of the polder area is generally low and flat, while the exterior is built with several sluice gates, pumping stations, and irrigation-drainage facilities. Therefore, it is very necessary to find a hydrological model and calibration, as well as the internal water circulation characteristics in the plain polder area of the southern plain of China. Taking the Northern Polder of Lujiang County, Anhui Province of China as the study area, a spatial division was proposed with the improved SWAT model using the "burn-in" algorithm and artificial correcting of sub-basins and river networks. A multi-water source irrigation system was also constructed to add the virtual reservoirs in the polder area, considering the irrigation characteristics. A multi-objective hydrological rate determination was then established using monthly time scales for the polder areas. The different sizes were finally classified to consider the drainage characteristic in the polder areas. The results show that the relative error of the monthly runoff at the outlet of most polder areas was within ±15%, the coefficient of determination was greater than 0.7, the Nash-Sutcliffe efficiency coefficient was greater than 0.6, and the simulation performance was at a medium or good level, indicating the improved SWAT model suitable for hydrological simulation in the study area. The simulated runoff process of a few polder outlets was deviated greatly from the measured one, possibly because the outflow of some pumping stations was artificially affected, resulting in the runoff process out of synchrony with the precipitation. The water balance analysis showed that the precipitation and water diversion from the outer rivers were converted mainly into runoff and evapotranspiration, whereas, the water diversion of outer rivers was approximately equal to the pumping capacity of pumping stations. Besides, a small part was discharged out of the basin through deep leakage. A large amount of evapotranspiration was due mainly to the high intensity of evapotranspiration with rice as the main crop. The coefficient of runoff was smaller than the average coefficient of runoff in the Yangtze River Basin. The reason was that the amount of water was emitted by the evapotranspiration and deep leakage, due to the damming effect of ponds, ditches, inner rivers, and other water bodies in the polder and the drainage of artificially regulated pumping stations. There was a 15% increase in the water diversion from the outer river and the drainage from the pumping station under the single-source irrigation scenario, compared with the current scenario. By contrast, there were a 30% reduction in the pumping drainage and a 60% reduction in the deep leakage without irrigation. The irrigation water consumption showed that the outer river was the main irrigation source, where the proportion of the water supply was more than 80%. The amount of water used for irrigation in the rice season was much greater than that in the wheat season. Among them, the main irrigation water sources for the rice season were the outer river and the polder inner river, whereas, the wheat season was from the outer river and the polder channel. The improved SWAT model can provide an effective way of water management in the polder area of the southern plain of China. [ABSTRACT FROM AUTHOR]