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目的在接受体外受精/胞浆内单精子注射-胚胎移植（IVF/ICSI-ET）治疗并取得妊娠的周期中，特别是在10~20个获卵数的“magic”范围内，确定迟发性中重度卵巢过度刺激综合征（OHSS）的危险因素。方法采用回顾性队列研究方法，对2017年12月至2018年12月在广州医科大学附属第三医院接受IVF或ICSI-ET的1 386例妊娠周期资料进行分析。对发生迟发性中重度OHSS的患者数据与其他妊娠周期数据进行对比，采用单因素方差分析和卡方检验计算两组的差异。用logistic回归分析确定迟发性中重度OHSS的危险因素。结果获卵数和妊娠囊数目是迟发性中重度OHSS的危险因素，总Gn剂量为其保护因素（PPP=0.003）为危险因素。两者的OR值分别为0.948和2.209，95%CI分别为（0.922， 0.975）和（1.278， 3.222）。AUC分别为0.624和0.595，95%CI分别为（0.565， 0.684）和（0.529， 0.661）。总Gn剂量（PP

SDN（软件定义网络）有效地简化了网络的配置与管理,使网络的革新更加快捷。利用控制器作为ARP（地址解析协议）代理,能显著地减小数据层面的广播流量,缓解因广播带来的带宽资源浪费。然而,控制器多采用被动的方式下发流表,在处理大量的广播包时会产生极大的扩展性问题。文章提出了一种基于SDN的分布式ARP代理方法,将多个局域网的网关作为ARP代理,各局域网内部的ARP请求报文以单播的方式转发到其网关做统一处理。实验结果表明,该方法不仅大大减少了网络中的广播流量和ARP请求响应延时,而且极大地缓解了SDN控制器的负载,提高了SDN的扩展性。

漂流，因而生命有無限可能；遷移，因而生命有如河流般長遠。本文敘事探究描述的是一位臺商子女維妮在中國大陸的教育與文化經驗。從13歲小學畢業後，進入中國大陸的教育體制，維妮在當地求學10年，從中學到大學，求學、就職經歷共有13年之久。維妮，具有不同於臺灣成長的教育經歷，臺商子女面臨哪些成長經歷、認同和自由的選擇，遷移世代具有如何與眾不同的文化特質？我們教育可以關心的是什麼？可以做些什麼？遷移如何造就新的一代？他們又如何思索自己與文化、地方的觀念？女性主義常常批判主流意識的許多看法，多元詮釋和看法與主流不同，並產生新的故事。敘事探究中，研究者與維妮一起探索建構和協商合作她的故事。在後殖民文學中，Naipaul也曾分析自己這樣的文化碰撞，認為認同鬆散的人，反而使自己處於「建構／拆解」、「接納／拒絕」、「同化／異化」的曖昧狀態，卻也使他創作出靈魂的文本，超越國界的人類關懷。瞭解遷移世代具有自我敘說的文本，說出他們的故事，也道出教育中少數族群的位置所在。 The study focuses on “Moving Generation”. The girl lived in the Mainland China about 13 years. The Children of Taiwanese Businessmen name is “Winnie” This research’s methodology included the literature review, narrative inquiry. Through Winnie’s story, we can understand her life and identity. What do they learn there and whether children can adapt to their life? Winnie has deep experience and local culture in Mainland China. Understand “Moving Generation” have their story and social context. And we can face up to a great diversity of the generation.

近年來批判教育學逐漸成為臺灣教育社會學領域中的重要論述，對於反省臺灣教育的深層結構和實踐提出許多的質疑和呼籲。本文主要探討兩個面向：一是了解批判教育學的學說特徵，將之視為一種對抗權力、朝向主體解放的文化論述和民主實踐；二是探討當代批判教育學所遭受的批評和學說分歧，了解批判教育學的不同修正版本，並將上述現象視為文本政治的過程。結語部分包含對批判教育學在臺灣的觀察和省思。 Critical Pedagogy has become an increasing important academic discourse in the field of sociology of education recently which provided many questions and warnings for reflecting the structure and practice of education in Taiwan. Briefly, there are two main domains in this articles: one is to clarify the characters of critical pedagogy by treating it as the discourses and practice toward struggle of power, liberation and praxis of democracy, the other is to investigate the criticism and division of critical pedagogy, explore different versions of critical pedagogy and put it as a process of textual politics. The conclusion including the discussions about the influences and implications of critical pedagogy in Taiwan and some reflections.

In order to screen new varieties of flue-cured tobacco suitable for the ecological environment of Xunyi tobacco area, and to provide a basis for the production and utilization of high-quality tobacco leaves, we used Qinyan 99 as the control in 2022, which was the main cultivar in Xunyi tobacco growing area. The differences in field growth period, botanical properties, agronomic properties, field natural incidence rate, economic properties, conventional chemical composition content, appearance quality and sensory quality of flue-cured tobacco were compared among Qinyan 99, Qinyan 96, Qinyan 201, Zhongyan 100, Yuyan 13 and Y2001. Results showed that there was little difference in the growth period among different tobacco varieties, ranging from 142 to 155 days; Qinyan 96 and Y2001 had strong growth potential in the field, strong disease resistance, high yield, output value and the proportion of medium to high grade tobacco. They had excellent appearance and sensory quality, and good coordination of chemical components, which could be used as reserve varieties for promotion and planting in Xunyi tobacco area. [ABSTRACT FROM AUTHOR]

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Objective To investigate the clinical characteristics and risk factors of mixed connective tissue disease associated with pulmonary arterial hypertension (MCTD-PAH). Methods Twelve MCTD-PAH patients diagnosed by right heart catheterization (RHC) at Tianjin Medical University General Hospital were retrospectively included, and 36 MCTD patients without pulmonary arterial hypertension (MCTD-non-PAH) were randomly selected from the same period of hospitalization based on gender and age. The clinical features and auxiliary examination of the two groups were compared, and the survival status of the two groups was compared. Results The proportion of dyspnea after activity, myositis and pericardial effusion were higher in the MCTD-PAH group than those of the control group. Serum sedimentation rate and immunoglobulin G (IgG) levels were higher in the MCTD-PAH group. Multivariate Logistic regression analysis showed that dyspnea after activity and high level of IgG were risk factors for predicting the occurrence of PAH in MCTD. Three patients (16.7%) died in the MCTD-PAH group, and no patients died in the control group. Conclusion Pulmonary arterial hypertension is one of the serious complications of MCTD. MCTD patients have shortness of breath after activity and high level of IgG should be wary of concomitant PAH. [ABSTRACT FROM AUTHOR]

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Objective To explore the efficacy of periodontal-guided tissue regeneration (GTR) combined with orth‑ odontic treatment for patients with malocclusion and periodontal disease. Methods Ninety patients with malocclusion and periodontal disease were selected. According to the envelope method, they were divided into the conventional group and the GTR group, with 45 cases in each group. Patients in the conventional group received periodontal basic treatment and orthodontic treatment, and patients in the GTR group received GTR treatment based on the conventional group. The therapeutic effect, periodontal index, gingival inflammation index, quality of life and safety index were compared between the two groups. Results After treatment, the total effective rate in the GTR group was 95. 56% (43/45), which was higher than that ［82. 22% (37/45) ］ in the conventional group, with statistically significant difference (P<0. 05) . After treatment, gingival index (GI) and sulcus bleeding index (SBI) in the two groups decreased, and those in the GTR group were lower than those of the conventional group (both P<0. 05) . After treatment, interleukin-6 (IL-6), matrix metalloproteinase-8 (MMP-8) and C-reactive protein (CRP) in the two groups decreased, and those were lower in the GTR group than in the conventional group (all P<0. 05) . After treatment, the scores of oral health-related quality of life in the two groups decreased, and that in the GTR group was lower than that of the conventional group (P<0. 05) . The incidence of adverse reactions in the GTR group was 4. 44% (2/45), which was lower than that ［20. 00% (9/45) ］ of the conventional group (P<0. 05) . Conclusions GTR combined with orthodontic treatment can effectively improve the therapeutic effect of patients with malocclusion and periodontal disease, improve the periodontal health status, inhibit inflammation response, improve the quality of life, and reduce postoperative adverse reactions [ABSTRACT FROM AUTHOR]

Ferritin is a class of proteins ubiquitously found in various types of nucleated organisms and involved in the iron homeostasis regulation of body. Ferritin can self-assemble to form a hollow nanocage of about 14 nm in size and is often used as carrier for drug delivery and vaccine construction. The crystal structure of Mycoplasma ferritin shows atypical ferroxidase centres and new pathway for Fe2+ uptake, which are structurally different from those of other species. Not much work has been reported for Spiroplasma ferritin. Here, our studies show that Spiroplasma ferritin has low sequence similarity with other ferritins including Mycoplasma ferritins. Spiroplasma eriocheiris Ferritin (SeFer) was recombinant expressed in E. coli in soluble form after IPTG (isopropyl-beta-D-thiogalactopyranoside) induction. High-purity SeFer protein was obtained after purification by DEAE (diethylaminoethyl) weak anion exchange chromatography and gel filtration. Crystal screen of SeFer was performed by sitting drop vapor diffusion at 4℃ and 18℃. SeFer crystals grew in several screen conditions. The best crystal diffracted to 2.90 Å by synchrotron radiation source and it belonged to the I432 space group. The X-ray crystallography data collected here can be used for further structure determination. Native-PAGE, dynamic light scattering, and the position of peaks of SeFer in molecular sieve showed that the molecular weight of SeFer is about 400.0 kD, and the diameter of SeFer was about 15 nm, both of them are close to the theoretical value. The structural model of SeFer was predicted by using Alphafold 2. The predicted model shows that SeFer has a regular icosahedral overall structure, which is similar to other ferritins. However, SeFer model shows that the key residues of ferroxidase center differ from those of mycoplasma ferritin. Our results not only provide a basis for studying the crystal structure of SeFer, but also provide new candidates for vaccine vectors. [ABSTRACT FROM AUTHOR]

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