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目的探讨 T1 灰阶反转（rT1）图对中轴型脊柱关节炎（ax-SpA）骶髂关节结构性病变的诊断价值。方法回顾性搜集我院 2020 年 2 月至 2022 年 12 月在 1 周内行骶髂关节MRI 及 CT 检查并符合 ax-SpA 诊断标准的患者52例， 共计104 个骶髂关节。两名放射科医师基于常规T1WI、rT1、T1WI + rT1三组图像，分别评估ax-SpA骶髂关节结构病变：骨侵蚀、骨质硬化、关节间隙改变，在斜冠状位图像上将骶髂关节分为前、中、后 3 部分，每部分分骶面、髂面，共6个区域，并按拟定评分规则对上述 3 种结构性病变进行评分，其中1名医师间隔1月后再次进行评分。由第3名肌骨影像专科医师同样使用上述方法评估CT图像作为参考标准。使用组内相关系数（ICC）分析医师间及医师内分别评估各病变评分一致性；采用Friedman M检验比较三组图像对各病变评分与 CT评分的差异；以 CT为参考标准，采用诊断性试验分析计算三组图像诊断骨侵蚀、骨质硬化及关节间隙改变的准确率、灵敏度、特异度，并采用McNemar 检验比较rT1、T1WI + rT1与T1WI的差异。结果三组图像评分各类结构病变医师间、医师内一致性好，其中以T1WI + rT1 的一致性最优，评估各类病变ICC≥0.856 95%CI（0.794，0.900），优于rT1及T1WI［ rT1：ICC≥0.819 95%CI（0.745，0.874），T1WI：ICC≥0.754 95%CI（0.656，0.827）］；T1WI + rT1对各病变的评分结果与CT评分结果相当， rT1对骨侵蚀、关节间隙改变评分与CT相当（P＞0.05）。相较T1WI，T1WI + rT1诊断各病变均有更高的准确率及灵敏度（准确率骨侵蚀：90.3% vs 76. 9%；灵敏度骨侵蚀： 91.6% vs 76.1%；准确率骨质硬化：89.4% vs 80.8%；灵敏度骨质硬化： 84.6% vs 73.9%；准确率关节间隙改变： 86.5% vs 73.1%；灵敏度关节间隙改变： 84.9% vs 60.4%；P1提高了对骨侵蚀、关节间隙改变诊断的准确性和灵敏度（准确率骨侵蚀： 87.5% vs 76.9%；灵敏度骨侵蚀： 88.7% vs 76.1%；准确率关节间隙改变： 85.6% vs 73.1%；灵敏度关节间隙改变： 83.0% vs 60.4%；P1能提高ax-SpA骶髂关节结构性病变的诊断效能，T1WI + rT1效能更优。

针对使用广泛的500 kV架空输电线路，分别研究了在轻、中、重冰区，由断线及不均匀覆冰引起的导线张力对输电杆塔安全性和经济性的影响。研究表明：导线张力增加0～20%，若保持杆塔杆件规格不变，悬垂塔的超限杆件比例为0～51%，耐张塔的超限杆件比例为0～4%；若增大杆塔杆件规格以保证安全，悬垂塔的塔重增加0～28%，耐张塔的塔重增加0～5%；覆冰越厚，由断线引起的导线张力对杆塔影响越小，由不均匀覆冰引起的导线张力对杆塔影响越大；导线张力主要影响悬垂塔横担上、下平面交叉材、塔身主斜材等杆塔杆件。因此，对重要输电线路和输电线路重要区段，推荐重点加强悬垂塔的防串倒及抗冰能力。研究结论对工程实践具有一定的指导意义。

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Remote sensing technology has become an important means of extracting agricultural information. In order to explore the identification and classification of crops of different remote sensing data sources, we selected Babu District Dongrong vegetable industry demonstration zone supplied to HongKong as the research area. Base on Planet, GF6 WFV, Landsat 8 OLI remote sensing images, we used the support vector machine method to identify and extract different crops of the tip leaves of bean, Xuedou, Qingzai, vegetable heart of pointed leaf, cabbage mustard. We also evaluated the extraction effect through class separability, overall classification, Kappa coefficient, spectral variation and mapping effect. Results showed that GF6 WFV images were the best resource for crop recognition and extraction in the study area. [ABSTRACT FROM AUTHOR]

Objective: To investigate the relationship between serum hemoglobin A (HbA1c), 25 hydroxyvitamin D [25(OH)D], matrix metalloproteinase-9 (MMP-9) and postoperative dry eye in patients with type 2 diabetes mellitus (T2DM) complicated with cataract. Methods: 162 patients with T2DM complicated with cataract who underwent phacoemulsification combined with intraocular lens implantation in our hospital from January 2019 to December 2023 were selected, patients were divided into dry eye group (53 cases) and non-dry eye group (109 cases) according to whether dry eye occurred after surgery. The levels of serum HbA1c 25(OH)D and MMP-9 were detected. The factors of postoperative dry eye in patients with T2DM complicated with cataract surgery were analyzed by multivariate Logistic regression, the predictive value of serum HbA1c 25 (OH)D and MMP-9 levels for postoperative dry eye in patients with T2DM complicated with cataract were analyzed by receiver operating characteristic (ROC) curve. Results: Compared with non-dry eye group, the levels of serum HbA1c and MMP-9 in dry eye group increased, and the level of 25(OH)D decreased (P < 0.05) Multivariate Logistic regression analysis showed that prolonged course of T2DM ( OR = 1.245 . 95%CI: 1.007~1.539), elevated HbAte (OR = 3.132, 95% CI: 1.745-5.624), and elevated MMP-9 (OR = 1.206 95%CI: 1.091~1.333) were independent risk factors for postoperative dry eye in patients with T2DM complicated with cataract surgery, Elevated 25 (OH) D ( OR = 0.854, 95% * CI 0.773~0.945) was an independent protective factor (P < 0.05) ROC curve analysis showed that, the area under the curve of combined prediction of serum HbA1c, 25(OH)D and MMP-9 levels for postoperative dry eye in T2DM patients with cataract was 0.921 (95%CI: 0.868~0.957), which was greater than 0.793 (95%CI: 0.723~0.853), 0.779 (95%CI: 0.707~0.840) and 0.783 (95%CI: 0.711~0.844) predicted by serum HbA1 25(OH)D and MMP-9 levels alone. Conclusion: Elevated preoperative serum HbAte and MMP-9 levels and the decrease of 25 (OH)D levels in patients with T2DM complicated with cataract are closely related to postoperative dry eye, and the combination of serum HbA1c 25 (OH)D and MMP-9 has a value in predicting postoperative dry eye in patients with T2DM complicated with cataract surgery. [ABSTRACT FROM AUTHOR]

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Copyright of Hydrogeology & Engineering Geology / Shuiwendizhi Gongchengdizhi is the property of Hydrogeology & Engineering Geology Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Modern Food Science & Technology is the property of Editorial Office of Modern Food Science & Technology and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objective To observe the effect of Selinexor (SEL) combined with Imatinib (IM) on the proliferation and apoptosis of Imatinib-resistant chronic myeloid leukemia K562/G01 (KG) cells and explore the possible mechanisms. Methods K562 cells and KG cells were treated with SEL or IM respectively or in combination. Cells viability was examined by MTT assay. Apoptosis was assessed by flow cytometry. BCR-ABL mRNA was detected by RT-PCR. XPO1 was detected by Western blotting. Results IM and SEL both inhibited the proliferation of K562 cells and KG cells; half maximal inhibitory concentration (IC50) for 48 h was 0.16 µmol/L vs. 6.48 µmol/L for IM and 132.0 nmol/L vs. 275.9 nmol/L for SEL. Compared with SEL or IM alone, SEL combined with IM significantly inhibited the proliferation of KG cells (P<0.05), induced KG cells apoptosis (P<0.05), downregulated the levels of BCR-ABL mRNA (P<0.05), and inhibited the expressions of XPO1 in KG cells (P<0.05). Conclusion SEL combined with IM can synergistically inhibit the proliferation and induce apoptosis of KG cells, and then inhibit the expressions of BCR-ABL mRNA and XPO1 to exert an anti-leukemia effect. [ABSTRACT FROM AUTHOR]

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目的　探讨多普勒超声辅助跟骨外侧动脉定位方法在跟骨骨折患者扩大L形切口切开复位内固定手术 中的应用效果。方法　选择跟骨骨折患者24例，随机分为超声组和对照组，每组12例。两组均行扩大L形切口切 开复位内固定手术治疗，超声组术前通过多普勒超声确定跟骨外侧动脉体表定位点。记录两组手术时间、术中C臂 透视次数、术中出血量、骨折愈合时间，两组术前及术后 3、12个月行跟骨侧位 X线片检查并测量 Bohler角、Gissane 角；比较两组术后1、3、12个月的疼痛视觉模拟评分 (VAS)，术后3、12个月的美国足踝外科学会 (AOFAS)评分，以及 术后并发症发生率。结果　超声组手术时间短于对照组 (P<0. 05)。两组术中透视次数、术中出血量、骨折愈合时 间比较差异均无统计学意义 (P 均>0. 05)。与同组术前比较，两组术后 3、12个月 Bohler角、Gissane 角均升高 (P 均 <0. 05)；两组术后3、12个月Bohler角、Gissane角比较差异均无统计学意义 (P均>0. 05)。两组术后1、3、12个月VAS 及术后 3、12 个月 AOFAS 评分比较差异均无统计学意义 (P 均>0. 05)。超声组术后发生皮缘坏死 1 例 (8. 3%)；对 照组术后发生皮缘坏死 3 例、感染 1 例，并发症发生率为 33. 3%；超声组术后并发症发生率低于对照组 (P<0. 05)。 结论　跟骨骨折患者扩大L形切口切开复位内固定手术治疗前通过多普勒超声定位标记跟骨外侧动脉有助于缩短 手术时间、减少术后并发症的发生。 [ABSTRACT FROM AUTHOR]

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Objective To evaluate the efficacy of preoperative halo gravity traction (HGT) assisted surgery for severe congenital scoliosis (CS). Methods From October 2016 to December 2021, clinical data were retrospectively reviewed for 55 children with severe scoliosis undergoing HGT.There were 28 boys and 27 girls with an average age of (9.4±3.8) years.According to etiology, they were divided into two groups of congenital (n=28) and non-congenital (n=27). At pre-operation, post-traction and post-operation, radiographic films of whole spine in standing position was employed for measuring main curve, compensatory curve, thoracic kyphosis and lumbar lordosis, trunk balance in coronal and sagittal planes, shoulder height and T1-S1 height and evaluate the improvement of deformity.And the differential efficacy was examined between two groups. Results Cobb angle of major bend pre-operation in congenital and non-congenital groups was (88.9±14.1)° and (89.5±17.4)°; Cobb angle of compensatory bending (28.8±12.9)° and (33.3±12.9)°; thoracic kyphosis (74.1±21.0)° and (69.9±20.8)°; lumbar lordosis (47.9±13.4)° and (38.9±6.6)°; trunk balance in coronal plane (43.2±15.5) and (38.3±10.2) mm; sagittal torso balance (34.7±10.5) and (44.4±19.8) mm; shoulder height (22.8±11.8) and (13.9±12.1) mm; height of T1-S1 (24.3±5.4) and (27.2±5.2) cm.The above findings have demonstrated that after HGT, Cobb angle of major curvature in congenital and non-congenital groups were (64.2±14.6)° and (53.0±14.9)°; Cobb angle of compensated bending (16.5±10.3)° and (19.2±11.0)°; hosthoracic kypis (53.7±16.9)° and (48.3±14.4)°; lumbar lordosis (37.4±7.0)° and (30.2±8.0)°; trunk balance in coronal plane (24.6±12.0) and (20.3±11.6)mm; sagittal torso balance (30.7±2.9) and (19.1±11.6) mm; shoulder height (12.0±7.1) and (7.0±4.0) mm; T1-S1 height (28.1±5.0) and (31.5±5.0) cm; there were significant improvements as compared with those pre-traction (P<0.01). The correction rate of major curve in non-congenital group (41.3±8.7)% was significantly higher than that in congenital group (27.4±10.9)% after HGT (P<0.01) and no differences existed in other parameters between two groups (P>0.05). After operation, Cobb angle of major curvature in congenital and non-congenital groups were (41.7±13.9)° and (37.4±12.8)°; thoracic kyphosis (40.5±16.3)° and (38.4±8.9)°; lumbar lordosis (33.4±6.2)° and (25.9±7.9)°; trunk balance in coronal plane (19.4±8.2) and (19.1±6.0) mm; sagittal torso balance (18.6±11.2) and (20.3±11.4) mm; shoulder height (11.5±7.1) and (9.0±5.6) mm; height of T1-S1 (30.2±5.4) and (32.5±7.1) cm; there were significant improvements as compared with those pre-operation (P<0.01). However, there was no inter-group difference (P>0.05). Conclusion HGT for severe CS can correct structural scoliosis and compensatory scoliosis pre-operation, and correct trunk deviation in coronal and sagittal planes.Although the correction rate of CS is lower than that of non-CS, the final correction efficacy can be the same after HGT surgery. [ABSTRACT FROM AUTHOR]

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