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目的 沟通技能是神经科住院医师必须掌握的核心能力之一。本研究旨在了解神经科住院医师医患沟通技能现况，并初步探讨可能的提升方式。 方法 选择北京协和医院神经科25名住院医师为研究对象，在进行年度客观结构化临床考试（objective structured clinical examination，OSCE）考核时，同期采用医患沟通技能评价（set elicit give understand end，SEGUE）量表评估其医患沟通能力，SEGUE量表包括5个维度，分别是“问诊准备”“信息收集”“信息给予”“理解患者”及“结束问诊”，共计25分。分析神经科住院医师医患沟通能力的常见薄弱环节、表现方式，并初步探讨可能的提升措施。 结果 25名住院医师均接受了医患沟通能力评估，平均分为（20.78±3.85）分，不同性别住院医师之间的差异无统计学意义[（20.81±3.68）分 vs.（20.50±4.29）分，P=0.86]。各评估维度平均分由高到低依次为“问诊准备”“理解患者”“信息收集”“信息给予”及“结束问诊”。其中，“进一步说明下一步诊疗方案”单项得分最低，“询问患者是否还有其他问题需要探讨”和“解释诊断性操作的理论依据”两项得分也较低。按照住院医师入职年限进行亚组分析，结果显示住院医师的医患沟通能力虽然随着入职年限增加而升高，但组间差异不具有统计学意义，且各组间不足之处相仿。 结论 神经科住院医师医患沟通能力存在欠缺，且这种不足并未随着临床实践的积累得到显著提高。提高神经科住院医师的医患沟通能力，不仅需要持续提升专业技术能力，还要积极倡导开设系统、专业的医患沟通培训课程，从医疗技术和沟通技术两方面提高医患沟通的效果。 Abstract: Objective Communication skills are one of the core competencies in neurology residency training. This paper aimed to investigate the current status of doctor-patient communication skills among neurological residents, and thus explore possible means to improve them. Methods A total of 25 resident physicians in the neurology department of Peking Union Medical College Hospital were selected as the study subjects, and the doctor-patient communication skills was evaluated by set elicit give understand end (SEGUE) framework during the annual objective structured clinical examination (OSCE). The SEGUE framework consists of 5 dimensions with a full score of 25 points. They are "set the stage" "elicit information" "give information" "understand the patients" and "end the encounter". To analyze the common weaknesses and manifestations of doctor-patient communication skills of neurology residents, and then discussed the possible improvement measures. Results All of the 25 residents received evaluation of doctor-patient communication skills with a mean score of 20.78±3.85, and the difference between different genders was not statistically significant (20.81±3.68 vs. 20.50±4.29, P=0.86). The dimension of "set the stage" reached the highest score, followed by "understand the patients" "elicit information" "give information" and "end the encounter". Among all of the items, the score of item "review next steps with patient" was the lowest, the other two items, "ask if there is anything else patient would like to discuss" and "explain rationale for diagnostic procedures", also had very low scores. Subgroup analysis based on the employment year of resident showed that although the doctor-patient communication skills of residents improved with the increasing of employment year, the difference between the subgroups was not statistically significant. A similar pattern of shortcomings was observed among the different subgroups. Conclusions Doctor-patient communication skills of neurological residents are insufficient, which could not be significantly improved with the accumulation of clinical practice. To improve the doctor-patient communication skills of neurology residents, it is not only necessary to continuously improve the professional technical ability, but also to actively advocate the establishment of systematic and professional doctor-patient communication training courses. Improve the effect of doctor-patient communication from two aspects of medical technology and communication technology.

Copyright of Evaluation & Analysis of Drug-Use in Hospitals of China is the property of Evaluation & Analysis of Drug-Use in Hospitals of China Editorial Board and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Evaluation & Analysis of Drug-Use in Hospitals of China is the property of Evaluation & Analysis of Drug-Use in Hospitals of China Editorial Board and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Clinical Neurosurgery / Linchuang Shenjingwaike Zazhi is the property of Editorial Board of Journal of Clinical Neurosurgery and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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AIM： This study aimed to investigate the effects of hsa-miR-204-5p on the viability, migration, cell cycle, and apoptosis of human vascular endothelial cells. METHODS： We established a model using the hsa-miR204-5p mimic in the human umbilical vein endothelial cell line EA. hy926. We evaluated the effects of hsa-miR-204-5p on endothelial cell functionality through various analyses, including cell scratch, Transwell, CCK-8, cell cycle, and apoptosis assays. Subsequently, we employed RNA sequencing and RT-qPCR to predict and verify the downstream target genes of hsa-miR-204-5p. Genes meeting the criteria of log2FC≤−0. 5 and P<0. 05 in RNA sequencing and those predicted as downstream target genes of hsa-miR-204-5p by the miRWalk database were intersected. Furthermore, we conducted Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment analyses. RESULTS: Overexpression of hsa-miR-204-5p inhibited the viability and migration of EA. hy926 cells, and reduced their apoptotic rate and the proportion of cells in S phase. Enrichment analyses showed that downstream target genes of hsa-miR-204-5p, including MAPT, PPP3R1, PRKACB, PTPRR, MAP2K4, CACNA2D2 and RPS6KA6, exhibited enrichment in MAPK signaling pathway. RT-qPCR results revealed that the mRNA expression levels of MAPT and MAP2K4, especially MAPT, were significantly down-regulated after overexpression of hsa-miR-204-5p. CONCLUSION: The findings suggest that hsa-miR204-5p suppresses the biological behaviors of endothelial cells, such as viability, migration, and apoptosis, likely through the inhibition of MAPT/MAPK signaling pathway. [ABSTRACT FROM AUTHOR]

Objective: To analyze the influencing factors of nonalcoholic fatty liver disease (NAFLD) in healthy people, and to observe the changes of renal function and subclinical atherosclerosis relate indexes in NAFLD patients. Methods: 1398 patients who underwent general health examination in The Second Medical Center of Chinese PLA General Hospital from May 2019 to August 2022 were selected as study subjects, NAFLD was diagnosed as case group among study subjects, and the rest as control group. The influencing factors of NAFLD in healthy people were analyzed by univariate and multivariate logistic regression analysis, and the changes of renal function [serum creatinine (Scr), urea nitrogen (BUN), serum uric acid (UA), incidence of impaired renal function] and subclinical atherosclerosis-related indicators [intima-media thickness (cIMT), common carotid artery stiffness index (β), vascular pressure-strain elasticity coefficient (Ep), and single-point pulse wave velocity (PWVβ)] in NAFLD patients were observed. Results: Of the 1398 subjects, 1372 completed the survey, with a completion rate of 98.14% (1372/1398). 184 cases were diagnosed as NAFLD among study subjects, which were included in case group, and the remaining 1188 cases were included in control group.The detection rate was 13.41% (184/1372). The results of univariate analysis showed that, the incidence of NAFLD was related to gender, body mass index, education level, nature of work, place of residence, exercise, preference for meat, preference for sweets, history of hypertension, history of hyperlipidemia, history of diabetes, family history of NAFLD, TG, fasting blood glucose, HDL-C, LDL-C and TC (P<0.05). The results of multivariate logistic regression analysis showed that, male gender, high body mass index, preference for meat, preference for sweets, high TG, high fasting blood glucose, high LDL-C, high TC and low HDL-C were risk factors for NAFLD, while exercise≥30 min/d was a protective factor for NAFLD (P<0.05). The Scr, BUN, UA and incidence of renal dysfunction in case group was higher than that in control group (P<0.05). The cIMT, β, Ep and PWVβ in case group were higher than those in control group (P<0.05). Conclusion: Male gender, high body mass index, preference for meat, preference for sweets, high TG, high fasting blood glucose, high LDL-C, high TC and low HDL-C were risk factors for NAFLD, while exercise≥30 min/d was a protective factor for NAFLD. NAFLD patients have the risk of renal function damage and subclinical atherosclerosis, which is worthy of clinical attention. [ABSTRACT FROM AUTHOR]

Copyright of Shipin Kexue/ Food Science is the property of Food Science Editorial Department and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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[Objective] The effect of foliar spraying selenium fertilizer on grain yield and rice quality of different indica and japonica rice varieties under straw returning and panicle fertilizer treatment was studied. [Method] At heading stage, 0.2% sodium selenite solution was sprayed on the leaves of rice treated with straw returning and spike fertilizer, and effect of foliar spraying selenium on rice quality and selenium content of different rice varieties were studied. [Result] Compared with the treatment without selenium, foliar selenium spraying treatment increased the average yield of Yangdao 6 and Nanjing 9108 by 1.465% and 3.54% respectively, and Nanjing 9108 increased slightly, and the response of straw returning to the field was slightly greater than that of straw returning to the field; the average milled rice rate of Yangdao 6 and Nanjing 9108 was increased by 1.62% and 0.70% respectively, and the increase rate of Yangdao 6 was slightly higher than that of Nanjing 9108; it can slightly reduce the chalky grain rate of Yangdao 6 and Nanjing 9018,but has no significant effect on the aspect ratio and chalkiness. It can slightly increase the amylose content and gelatinization temperature of Yangdao 6 and Nanjing 9018, among which Yangdao 6 increased slightly after spraying selenium, while Nanjing 9108 increased slightly in gelatinization temperature and protein content after spraying selenium. The disintegration value of Yangdao 6 and Nanjing 9108 rice increased by 2.61% and 3.52% respectively, and the reduction value decreased by 1.82% and 0.82% respectively; the selenium content in the stem sheath, leaves, ears and polished rice of Yangdao 6 and Nanjing 9018 was significantly increased, and the selenium content of Nanjing 9108 polished rice increased slightly. After selenium treatment, the selenium content of polished rice of the two varieties reached the safe standard of selenium-enriched rice. [Conclusion] Foliar spraying of selenium fertilizer can effectively increase the selenium content in polished rice, and moderately improve the processing quality, appearance quality and main characteristic values of rice starch viscosity. [ABSTRACT FROM AUTHOR]

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Copyright of Journal of Hydrobiology is the property of Editorial Department of Journal of Hydrobiology and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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Copyright of Journal of Architecture & Civil Engineering is the property of Chang'an Daxue Zazhishe and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Chemical Engineering (China) / Huaxue Gongcheng is the property of Hualu Engineering Science & Technology Co Ltd. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

叉指数优化选择是传统MMSE-Rake（最小均方差Rake接收机）算法的重要组成部分,广泛应用于UWB（超带宽）Rake接收机中。为了提高在低速传输条件下UWB系统对多径信号接收的快速识别能力,提出了一种基于优化抽头系数的MBER（最小误比特率）改进算法,该算法可在不降低多径分辨率的前提下,通过简化Rake叉指数实现快速定位。仿真结果表明,在低速CM3（NLOS信道）和CM4（特殊情况下NLOS信道）多径模拟信道传输条件下,改进后的算法在性能上优于传统MMSERake算法,不仅降低了Rake接收机的复杂度,还提高了信号接收的实时性。

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Copyright of Chinese Journal of Stroke is the property of Chinese Journal of Stroke Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Forensic Medicine / Fayixue Zazhi is the property of Journal of Forensic Medicine Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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Copyright of Journal of Shanghai University / Shanghai Daxue Xuebao is the property of Journal of Shanghai University (Natural Sciences) Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Shipin Kexue/ Food Science is the property of Food Science Editorial Department and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objective: To explore the effect of acacetin on myocardial ischemia reperfusion injury in rats and its possible mechanism. 24 SPF rats were randomly divided into sham operation group, model control group, acacetin administration group, acacetin+AG490 group, with 6 rats in each group. Myocardial ischemia reperfusion injury model was induced by 30 minutes coronary occlusion followed by 2 h reperfusion in rats. The myocardial infarct area was measured by triphenyltetrazolium chloride, the activities of CK-MB and LDH in serum were detected by ultraviolet spectrophotometer and enzyme linked immunoassay, and the relative expression levels of Bcl-2, Bax, Stat3 and p-Stat3 proteins in myocardium were investigated by Western blot. Compared with the sham operation group, the activities of CK-MB and LDH in serum rose obviously in the model group (P<0.01), the percentage of myocardial infarction area increased significantly (P<0.01), the ratio of p-Stat3/Stat3 and Bcl-2/Bax decreased notably (P<0.01); Compared with the model group, the activities of CK-MB and LDH, the percentage of myocardial infarction area were significantly decreased (P<0.05), and the ratios of Bcl-2/Bax and p-Stat3/Stat3 were increased significantly in the acacetin treated group. However, the protective effect of acacetin on damaged myocardium was cleared by AG490 in the group of acacetin+AG490. Acacetin could alleviate myocardial damage and exert myocardial protection in MIRI rats, and its mechanism might be related to the inhibition of cardiomyocyte apoptosis by activating Jak2/Stat3 signal pathway. [ABSTRACT FROM AUTHOR]

OBJECTIVE: To probe into the application effect of the Internet of Things health management model in elderly patients with multiple medications. METHODS: A total of 134 elderly patients with multiple medications admitted into the hospital from Jan. 2019 to Sept. 2021 were selected and divided into observation and control group via simple randomization method. The control group was given routine management, while the observation group was given IoT health management model. The awareness of drug-related knowledge, medication compliance and burden of medication before and after intervention were compared between two groups, and the medication safety of the two groups after intervention were evaluated. RESULTS: After intervention, the awareness of drug-related knowledge in the observation group was higher than that of the same group before intervention, and higher than that of the control group, with statistically significant differences (P<0. 05); after intervention, the medication compliance of both groups had been increased, and that of the observation group was higher than the control group, with statistically significant differences (P<0. 05); after intervention, scores of the burden of medication in both groups had been decreased, and that of the observation group was lower than the control group, with statistically significant differences (P<0. 05). The incidence of adverse drug reactions of the observation group was 22. 39% (15/67), which was lower than that of the control group (26/67, 38. 81%), with statistically significant difference (P<0. 05). CONCLUSIONS: The IoT health management model can effectively improve the awareness of drug-related knowledge and medication compliance of elderly patients with multiple medications, reduce the burden of medication, and improve medication safety. [ABSTRACT FROM AUTHOR]

用溶胶-凝胶法合成了发蓝绿光的4SrO·7Al2O3:Eu2+高显色荧光粉.从XRD、DTA以及红外谱图得出当干凝胶经1200℃灼烧可以完全形成4 SrO·7Al2O3晶相,这比用高温固相合成法低了200℃.通过激发光谱和发射光谱分析其发光特性,随着灼烧温度的升高,其发光强度增大.