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Copyright of Electric Power Engineering Technology is the property of Editorial Department of Electric Power Engineering Technology and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Chinese Journal of Osteoporosis is the property of Chinese Journal of Osteoporosis and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Chinese Journal of Osteoporosis is the property of Chinese Journal of Osteoporosis and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objective To detect the expression of key factors of Wnt /β-catenin and ＲANKL /LGＲ4 pathways in fracture tissues of patients with osteoporotic fracture ( OPF) ． Methods Fifty-six patients with femoral fractures from January 2016 to July 2017 in our hospital were selected． Twenty-seven cases were divided into OPF group and 29 cases were divided into control group． Surgery was performed in 3 － 7 days． Bone tissue ( more than 200 mg) from the fracture area was collected and stored in liquid nitrogen． Total ＲNA was extracted from bone tissue using liquid nitrogen grinding ＲNAiso Plus method ． The difference of mＲNA expression of each factor was compared between the two groups using ＲT-PCＲ technique． Total protein was extracted from bone tissue using liquid nitrogen grinding and pyrolysis liquid． The protein expression difference of each factor was detected and compared between the two groups using Western blotting technique． Ｒesults ＲT-PCＲ and Western blotting result showed that LＲP5，β-catenin，Ｒunx2， C-myc，and LGＲ4 decreased，but ＲANKL increased in OPF group，comparing to those in the control group ( P ＜ 0. 05 ) ． Conclusion OPF is associated with the inhibition or weakening of osteogenic factors LＲP5，β-catenin，Ｒunx2，and C-myc in Wnt /β-catenin osteogenic signaling pathway，the increase of osteoclastic factor ＲANKL in ＲANKL /LGＲ4 osteoclastic signaling pathway，and the inhibition of osteoclastic factor LGＲ4． The occurrence and treatment of OPF can be intervened by regulating the expression of various factors． [ABSTRACT FROM AUTHOR]

Copyright of Chinese Journal of Osteoporosis is the property of Chinese Journal of Osteoporosis and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)