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The representative radioactive elemental iodine and methyl iodine are selected as adsorbates and the static adsorption capacity, adsorption heat and kinetics of silver based molecular sieves are investigated. The micro morphology, element composition and adsorption mechanism of the materials are characterized and analyzed by SEM, EDX mapping and XPS tests. The results show that the adsorption capacity of the material for elemental iodine and methyl iodine at room temperature can reach 1000 mg/g and 380 mg/g respectively, and the adsorption process for methyl iodine conforms to the quasi second order kinetic equation and Langmuair adsorption isotherm model. Silver based molecular sieves process trace radioactive iodine through chemical adsorption, while the main adsorption mode for higher concentration radioactive iodine is physical adsorption. [ABSTRACT FROM AUTHOR]

Objective: To study the expressions of IL-33 and its receptor ST2L in peripheral blood T cells and skin lesions of patients with psoriasis. Methods: The expression and distribution of IL-33 and ST2L in psoriasis vulgaris(PV group), psoriasis pustulosa(PP group) and nevus resection]control group(CON group)]were detected by immunohistochemical method. Western blot and RT-PCR were used to detect the expression of IL-33 and IL-33 mRNA in Jurkat T cells and HaCat keratinocytes induced by IL-17A, respectively. The same method was used to detect the expression of ST2L and ST2L mRNA in Jurkat T cells, PV group T cells, PP group T cells and CON group T cells after IL-33 induction. Results: In the skin lesions of patients in PV group and PP group, we observed positive staining of IL-33 and its receptor ST2L protein in epidermis and dermis cells with different densities; a small amount of IL-33 protein was expressed in T cells of CON group, but in psoriasis group, including PV group and PP group, IL-33 protein was significantly expressed in T cells, and the expression level of PP group was higher than that of PV group, the difference was statistically significant(P<0.05); IL-33 induced Jurkat T cells, PV group and PP group T cells to express a certain amount of ST2L protein and mRNA in a dose-dependent manner; the expression of ST2L protein in PV group and PP group were higher than the level of ST2L induced by IL-33 in CON group, and the difference was statistically significant(P<0.05). IL-17A induced Jurkat T cells to produce IL-33 protein and mRNA in a certain amount of effect and aging relationship; IL-17A induced the expression of IL-33 protein and mRNA in HaCat keratinocytes in a dose-dependent manner. IL-33 protein was mainly expressed in the nucleus of HaCat keratinocytes, and some of the cytoplasm had some expression, and the expression was significantly increased after high concentration of IL-17A stimulation. Conclusion: The expression levels of IL-33 and its receptor ST2L in peripheral blood T cells and skin lesions of patients with psoriasis are significantly increased, suggesting that IL-33 may play an important role in the occurrence and development of psoriasis. [ABSTRACT FROM AUTHOR]

To evaluate the effects of ultrasus-guided thoracic paravertebral nerve block (TPVB) and erectile spinal-plane block (ESPB) on perioperative stress response and analgesia in patients undergoing thoracoscopic surgery. Methods Ninety patients underwent thoracoscopic surgery under elective general anesthesia were included and randomly divided into the control group (group C), the ESPB group (group E) and the TPVB group (group T), with 30 cases in each group. Before anesthesia induction, no treatment was given to the group C, and the group E and the group T were treated with ultrasound guided ESPB and TPVB on the affected side, and injected with 20 mL of 0.5% ropivacaine. Patient controlled analgesia (PCIA) was connected after operation. The venous blood samples were collected immediately before operation (T0), 30 minutes after operation (T1) and at the time of tracheal catheter removal (T2) to test the concentration of blood glucose (Glu) and serum cortisol (Cor). The type of surgery, the duration time of surgery, the number of patients who needed to use phenylephrine and the amount of remifentanil for hypotension during operation were recorded. Visual analog scores (VAS) of patients at rest and coughing status at T2, 12 hours after operation (T3), 24 hours after operation (T4), 48 hours after operation (T5), the total number of PCIA compression and the total amount of PCIA sufentanil infusion within 48 hours after operation, the use of rescue analgesia, and the occurrence of adverse reactions were recorded. Results Compared with T0, concentrations of Cor and Glu at T1 and T2, were increased in patients (P＜0.05). Compared with the group C, Glu was significantly decreased in the group T, the resting VAS pain scores of T2, T3, T4 and T5 were decreased in the group T and the group E. The coughing VAS pain scores of T2 and T4 were decreased, and the intraoperative dosage of reifentanil, the number of PCIA compression and the total infusion of sufentanil were decreased. The remedial analgesic rate was decreased in the T group (P＜0.05). Compared with the group T, the resting VAS scores of T2, T3 and T4 were increased in the group E, and the coughing VAS scores of T3 were increased, the number of PCIA compression, remifentanil usage and the total infusion of PCIA sufentanil were increased. The percentage of intraoperative use of norepinephrine for hypotension was decreased (P＜ 0.05). Conclusion TPVB can inhibit the stress response of patients undergoing thoracoscopic surgery. TPVB could provide better postoperative analgesia than ESPB, and has a significant inhibitory effect on intraoperative blood pressure. [ABSTRACT FROM AUTHOR]

Objective: Atrial fibrillation is one of the most common arrhythmias. The mechanism of atrial fibrillation is not yet clear. A number of previous studies have shown that adipokines, including leptin, visfatin, are closely related to cardiovascular diseases.In this study, the relationship between leptin, visfatin and atrial fibrillation was investigated. Methods: In this study, the secretion levels of leptin and visfatin in peripheral blood and epicardial adipose tissue of AF group and control group were detected. To explore the relationship between leptin, visfatin and AF. Results: The average concentration of visfatin in peripheral blood serum of atrial fibrillation group was 15.95±10.44 ng/mL, and the sinus rhythm group was 20.28±12.90 ng/mL, and there was not statistically significant (P=0.169); The average concentration of leptin in peripheral blood in the atrial fibrillation group was 1.48 ng/mL, and in the sinus rhythm group was 2.56ng/mL. The comparison between the two was statistically significant (P=0.0027). Serum leptin levels in the sinus group were significantly higher than those in the atrial fibrillation group; In epicardial adipose tissue, the expression of leptin in the atrial fibrillation group was significantly lower than that in the control group (P=0.032), while the expression of visfatin was not statistically different between the two groups (P=0.06). Conclusions: The incidence of atrial fibrillation can be reduced by high levels of leptin in peripheral blood serum and epicardial adipose tissue. The levels of visfatin in peripheral blood serum and epicardial adipose tissue in patients with atrial fibrillation was not significantly different from those with sinus rhythm. Therefore there may not be a correlation between visfatin and atrial fibrillation. [ABSTRACT FROM AUTHOR]

【Objective】To explore the effects of continuous application of soil conditioner quicklime and organic fertilizer on the growth, development, and yield components of maize in acidic soil in the southeastern region of Liaoning.【Methods】From 2019 to 2021 field experiments were conducted in Fengcheng City, Liaoning Province. Four treatments were set up including no application of soil conditioner (CK), quicklime (CaO), organic fertilizer (Organic), and organic fertilizer+quicklime (Organic+CaO) . The effects of continuous application of soil conditioner on maize plant traits, dry matter accumulation, yield components, and other indicators were analyzed.【Results】From 2019 to 2021, the maize yield of CaO treatment were all higher than CK. The yield of Organic and Organic+CaO treatments were higher than CK in the first two years and were lower than the CK in the third year of continuous application. The yield increase of CaO treatment were in the range of 2.12% to 19.74%. The yield increase rates of Organic+CaO treatment were 15.74% and 7.89% in the first two years, respectively. But there was no yield increase effect in the third year of application. The year, soil conditioner, and their interaction had extremely significant effect (P<0.01) on maize yield. The yield of CaO and Organic+CaO treatments were significantly higher (P<0.05) than CK and the Organic treatments. The ear number of CaO treatment was significantly higher (P<0.05) than CK. CaO and Organic+CaO treatments had significantly higher (P<0.05) kernel number per ear and kernel number per hectare than that of CK and Organic treatment. 1 000-kernel weight in Organic+CaO treatment was significantly higher (P<0.05) than all other treatments. Yield was significantly positively correlated (P<0.05) with kernel number per ear (R2=0.614) and kernel number per hectare (R2=0.746) . Continuous application of soil conditioner could improve plant height, ear height, and the ratio of ear height to plant height of maize. And the effect on ear height was more than the effect on plant height. Leaf area index (LAI) increased rapidly in early growth stages and decreased slowly in later growth stages. The effects were more obvious for Organic+CaO and Organic treatments. Applying soil conditioner promoted the dry matter accumulation and post floral dry matter accumulation of all the growth stages. The effect of Organic+CaO treatment was better than that of Organic and CaO treatments.【Conclusion】Continuous application of CaO and Organic+CaO on acidic soil promoted the maize growth and development. However, from the yield prospective, when using Organic+CaO as soil conditioner in the southeastern region of Liaoning, continuous application for more than two years should be avoided. [ABSTRACT FROM AUTHOR]

Objective To observe the effect of thoracic paravertebral block (TPVB) combined with erector spinae plane block (ESPB) on postoperative analgesia and quality of recovery in patients underwent video-assisted thoracic surgery. Methods Ninety patients underwent video-assisted thoracic surgery were selected and randomly divided into the E group, the T group and the TE group (preoperatively receiving ultrasound-guided ESPB, TPVB and TPVB+ESPB, respectively), with 30 patients in each group. In the three groups, 0.5% ropivacaine 25 mL was used as local anesthetic. In the TE group, TPVB combined with ESPB was executed, and 5 and 20 mL local anesthetics were used successively. Patient-controlled intravenous analgesia (PCIA) was used as a rescue analgesia postoperatively. Data of hypesthesia at lateral chest wall at 30 min after completion of block, intraoperative incidence of hypotension and dosage of anesthetics were recorded. Patients were followed up for Numeric Rating Scales (NRS) score, time to first rescue analgesia, number of rescue analgesia, quality of recovery-15 score, analgesia satisfaction score, postoperative nausea and vomiting (PONV) scores in the first 24 h postsurgery and incidence of postoperative chronic pain at 6 months. Results The incidence of preoperative hypesthesia was higher in the TE group and the T group than that in the E group (P＜0.05). The intraoperative use of remifentanil was lower in the T group than that of the E group and the TE group, but the utilization rate of vasoconstricting drugs was the highest (P＜0.05). NRS scores at rest and coughing were lower in the T group than those in the E and TE groups (P＜0.05). There were no significant differences in the time to first rescue analgesia and the number of rescue analgesia between the three groups (P＞0.05). Compared with the E group, the T group had a better postoperative QoR-15 scores (P＜0.05), and the group TE had lower incidence of postoperative chronic pain (P＜0.05). There were no statistical differences in analgesia satisfaction scores and PONV scores between the three groups (P＞0.05). Conclusion The effects of TPVB+ESPB on postoperative analgesia and quality of recovery in patients underwent thoracoscopic surgery are not better than those of ESPB and TPVB, but it has a faster onset time of sensory block than ESPB and reduces the occurrence of postoperative chronic pain. [ABSTRACT FROM AUTHOR]

BACKGROUND: Neurodegenerative diseases are a large class of major neurological diseases that can lead to the loss of patients’ ability to work and live. At present, there is no effective treatment for this disease. Adipose-derived stromal cells can induce differentiation into nerve cells in vitro, which is expected to provide a new method for the treatment of this kind of diseases. OBJECTIVE: To explore the expression changes of Bax/Bcl-2 protein during the differentiation of adipose-derived stromal cells into astrocytes, and to further investigate whether there is mitochondrial pathway-mediated apoptosis during the induction. METHODS: Immunocytochemistry and western blot assay were used to analyze the expression of glial fibrillary acidic protein, Bax, Bcl-2, cytochrome C, and casepase-3 in the process of adipose-derived stromal cell differentiation into astrocytes when induction for 48 hours and 7, 14, and 21 days. Transmission electron microscopy was used to observe the ultrastructure of cells and mitochondria. RESULTS AND CONCLUSION: (1) After being induced for 48 hours and 7, 14, and 21 days, the expression of glial fibrillary acidic protein reached the peak on day 7 (P < 0.05). There was no significant difference in glial fibrillary acidic protein expression between 14 days and 7 days after induction (P > 0.05). (2) The expression of Bax, cytochrome C, and casepase-3 increased gradually with the induction time extending and reached the peak on day 14 (P < 0.05). The expression of Bcl-2 was decreased gradually and reached the lowest level on day 14 after induction (P < 0.05). (3) Typical apoptotic bodies and mitochondrial damage were observed using transmission electron microscopy. (4) Adipose-derived stromal cells were in the best survival and differentiation state at the 7th to 14th day of differentiation. During adipose-derived stromal cell differentiation into astrocytes, the inhibitory effect of Bcl-2 on apoptosis was significantly weakened, and the pro apoptotic effect of Bax was gradually enhanced. Cytochrome C was released into the cytoplasm by damaged mitochondria, which led to apoptosis in mitochondrial pathway. [ABSTRACT FROM AUTHOR]

A non-Pt electrocatalyst for porous carbon molybdenum carbide with ruthenium nanoparticles was prepared in this paper. The carrier was synthesized by using two dimensional conjugated carbonit and ammonium molybdate as precursors, and the active metal ruthenium was uniformly dispersed with the support of hydrothermal method. Their structure consists of N-doped atoms and nanopores. These holes create highly accessible catalytic sites and good charge transfer ability in the material, thus providing good reaction kinetics for hydrogen evolution reaction（HER) . N-doped atoms regulate the electronic properties of the catalytic active sites in the material, which reduces the free energy of adsorption and desorption of hydrogen components participating in the reaction, providing good catalytic activity for HER. [ABSTRACT FROM AUTHOR]

In order to solve the problem for controlling the deformation of the large-section sewage box culvert induced by the construction of an adjacent bored tunnel beneath, the code Midas GTS NX was performed to analyze the deformation characteristics of the existing box culvert with the different sewage flow rates induced by the construction of the bored tunnel beneath. The effects of the new tunnel construction were evaluated by field monitoring. The results show that changes in the sewage loads have a great influence on the magnitude of the settlements of the box culvert. The maximum settlement of the box culvert filled with sewage is 1. 75 times that of the box culvert without sewage. When the height of sewage is controlled below 0. 754 m, the safety of the box culvert could be ensured. The box culvert is greatly disturbed during the construction of the dewatering and excavation within the distance of about 13 m from the box culvert. The settlement of the box culvert at the stage accounted for 70% ~ 75% of the total settlement. The modified Peck formula using the superposition method was applied to describe the settlement curve of the box culvert. The settlement trough width of box culvert ranges from 6. 32 m to 6. 9 m in the construction of the bored tunnel. The fitting curve of the settlement of the box culvert is finally in the shape of “U”. [ABSTRACT FROM AUTHOR]

With the improvement in people’s awareness of diseases and the level of diagnosis and treatment, the incidence rates of immunoglobulin G4-related disease（IgG4-RD） and autoimmune liver disease（AILD） are constantly increasing, and IgG4-related sclerosing cholangitis is the overlapping part of the disease spectrum of IgG4-RD and AILD, while the association between IgG4-related autoimmune hepatitis（IgG4-AIH） and these two diseases remains unclear. This article reviews the hepatic manifestation of IgG4-RD, summarizes the clinical features of IgG4-AIH, and analyzes whether IgG4-AIH is a subtype of AIH or a hepatic involvement of IgG4-RD. It is believed that IgG4-AIH has similar but different clinical manifestations and histopathological features from classical AIH, and IgG4-AIH may be classified as two types, i.e., a subtype of AIH and the liver manifestation of IgG4-RD. The research on the pathogenesis, clinical features, and clinical diagnosis and treatment of IgG4-AIH should be taken seriously in future. [ABSTRACT FROM AUTHOR]

Northeast China is one of the largest industry and agricultural bases in China, but frequent flooding brings huge losses to the people and country. In order to forecast floods in Northeast China, we used commensurablility forecasting techniques, ordered network structure chart and butterfly structure diagram. The prediction selected extraordinary flooding years which occurred in the Northeast China since 1856, we found that these years had a very strong degree of commensurability by chi-square test, indicating that commensurability was non-accidental. Then it used ternary, quinary and septenary commensurability calculation models for forecasting, along with ordered network structure chart and butterfly structure diagram. It verified the inevitability of flooding in 2013 and showed that the Northeast China region would be highly prone to flooding in 2017. [ABSTRACT FROM AUTHOR]

目的　探讨RS402007基因多态性对脑梗死患者颈动脉粥样硬化斑块易损性及降脂疗效的影响。方法　选 取114例脑梗死患者, 根据颈动脉粥样硬化斑块情况分为稳定斑块组56例和易损斑块组58例。比较两组临床及血 液生化指标, RS402007（G/C）位点基因型及等位基因频率, 观察不同基因型患者阿托伐他汀降脂疗效。结果　两组治 疗前血清LDL-C, TC水平以及GG, GC, CC基因型构成差异有统计学意义（P均<0. 05）。与治疗前比较, GG, GC, CC 基因型患者治疗后血清LDL-C, TG, TC水平降低, HDL-C水平升高（P均<0. 05）；治疗后比较, CC基因型患者血脂水平 与GG基因型, CC基因型患者差异有统计学意义（P均<0. 05）。GG, GC, CC基因型患者降脂治疗有效率分别分别为 80. 65%, 84. 62%, 88. 64%。CC基因型患者有效率高于GG基因型, CC基因型患者（P均<0. 05）。结论 RS402007基因 多态性与颈动脉粥样硬化性斑块易损性相关且对药物的降脂疗效有一定影响。 [ABSTRACT FROM AUTHOR]

Nylon １２１１ was successfully synthesized using a step heating melt polycondensation．FT-IR and １H NMR were utilized to confirm the successful synthesis of nylon １２１１．Meanwhile, the thermal properties, crystal structures and relaxation processes of the samples were characterized by TGA, DSC, WAXD and DMA． When the melt Ｇcrystallizednylon １２１１ samples are heated from room temperature to a higher temperature, the WAXD measurement indicates that the crystal structure sof the samples transform from αＧ forms to γＧ forms． Thermal stability of nylon １２１１ was characterized using the TGA and DSC under nitrogen atmosphere． Nylon １２１１ has good heatres istance and thermal stability． The DMA measurement shows that nylon １２１１ has low Ｇ temperature flexibility and good cold endurance． Nylon １２１１ notonly possesses excellent mechanical properties but also has low water absorption, which make it suitable for uses requiring retention of mechanical properties and thermal properties under varying conditions of humidity. [ABSTRACT FROM AUTHOR]

The present situation of the third-party payment was introduced and the adverse impact of it on commercial banks was analyzed. Accordingly, some measures to eliminate the impact of the third-party payment such as accelerating the financial innovation by perfecting electronic financial channels of the banks, strengthening the cooperation with the third-payment organizations and increasing the number of customers by developing new customer groups are proposed. [ABSTRACT FROM AUTHOR]

For the weakness of the image quality assessment methods based on local computation, this paper proposed a nonlocal structure tensor based SSIM image quality assessment method. The primal eigenvalue of nonlocal structure tensor at each pixel well reflected the structural strength information, especially the details information such as texture and so on. And the orientation of the primal eignvector reflected the structural direction information. This paper used the similarity of the primal eigenvalues to describe the consistency of the structural strength between the reference image and the distorted image, and the cosine of the intersection angle betw een the primal eignveetors to characterize the similarity of the structural direction. Numerical experiment shows that the average computing time is 778.43 s by using this method to assess the images in TID2008 database. And the assessment result is close to the subjective assessment. [ABSTRACT FROM AUTHOR]

The incident number and death toll of cardio-cerebrovascular diseases increase continuously in China. The impairment of arterial baroreflex (ABR) is closely related to the genesis and development of cardio-cerebrovascular diseases (such as hypertension and chronic heart failure). Barostim neoTM (by American CRVx. Inc) can reduce blood pressure and heart rate by electrically stimulating carotid sinus baroreceptors and activating baroreflex. Therefore, it can be used to treat resistant hypertension, heart failure and end-stage renal disease, etc. The mechanism of baroreflex activation therapy (BAT) includes inhibiting sympathetic nervous system and rennin-angiotensin system, and increasing the activity of vagus nerve. Thus it improves baroreflex sensitivity and heart rate variability, and restores the structure and function of key organs. [ABSTRACT FROM AUTHOR]

Objective: To research the difference of the effects of anesthesia and postoperative pain relief between propofol combined with sufentanil and propofol combined with fentanyl in painless abortion. Methods: 208 cases with voluntarily painless abortion were selected in our hospital. They were randomly divided into experimental group (n=104) and control group (n=104). The control group was given propofol combined with fentanyl and the experimental group was given propofol combined with sufentanil intravenously. Recording MAP, SpO2, RR and HR at the time of premedication(T0), preoperation(T1), expanding cervix uterus(T2) and postoperation( T3). Recording the dosage of propofol, recovery time and VAS score of uterine pain after the operation. Adverse reactions were also recorded in both groups of patients. Results: Compared with those at T0, the MAP, SpO2, RR, HR were all statistically decreased at the time of T1 and T2 in both groups (P<0.05), but the difference were not significant between both groups (P>0.05). The dosage of propofol in the experimental group was lower than in the control group (P<0.05). The average recovery time was shorter and the VAS score of uterine pain and propofol injection pain were lower in the experimental group than in the control group (P<0.05). The incidence of nausea and vomiting and respiratory depression were lower in the experimental group than in the control group, but the difference was not statistically significant (P>0.05). Conclusion: Propofol combined with sufentanil was more effective than propofol combined with fentanyl, with better postoperative recovery. It is worth promoting application in painless abortion operation. [ABSTRACT FROM AUTHOR]

Objective: To research the difference of the effects of anesthesia and postoperative pain relief between propofol combined with sufentanil and propofol combined with fentanyl in painless abortion. Methods: 208 cases with voluntarily painless abortion were selected in our hospital. They were randomly divided into experimental group (n=104) and control group (n=104). The control group was given propofol combined with fentanyl and the experimental group was given propofol combined with sufentanil intravenously. Recording MAP, SpO2, RR and HR at the time of premedication(T0), preoperation(T1), expanding cervix uterus(T2) and postoperation( T3). Recording the dosage of propofol, recovery time and VAS score of uterine pain after the operation. Adverse reactions were also recorded in both groups of patients. Results: Compared with those at T0, the MAP, SpO2, RR, HR were all statistically decreased at the time of T1 and T2 in both groups (P<0.05), but the difference were not significant between both groups (P>0.05). The dosage of propofol in the experimental group was lower than in the control group (P<0.05). The average recovery time was shorter and the VAS score of uterine pain and propofol injection pain were lower in the experimental group than in the control group (P<0.05). The incidence of nausea and vomiting and respiratory depression were lower in the experimental group than in the control group, but the difference was not statistically significant (P>0.05). Conclusion: Propofol combined with sufentanil was more effective than propofol combined with fentanyl, with better postoperative recovery. It is worth promoting application in painless abortion operation. [ABSTRACT FROM AUTHOR]

Mandarin ke (rJ) is an emphatic modal adverb with multiple functions, but its origin has remained unclear. Although there have been different proposals regarding its etymology, they do not paint a complete picture, nor do they account for the differences in strong versus light intonation. This paper provides historical evidence to argue that the two forms of ke have different origins: The strong one originated from a modal verb and the light one from a rhetorical interrogative adverb. [ABSTRACT FROM AUTHOR]

Under the Internet plus background,online financing has been permeating every financial field.This brings subversive impact to the teaching of financial course. Accordingly,how to meet the need of rapid accelerating online financing by updating the teaching content and building an information-based teaching model centering on the students is a new issue. In this study,the requirements and characteristics of online financing are introduced. Besides,the defects and deficiencies of traditional finance course teaching are analyzed. Finally,two ways to reform the finance course teaching are given. [ABSTRACT FROM AUTHOR]

Objective: To explore the risk factors of lower extremity deep venous thrombosis(DVT) after gynecologic laparoscopic surgery. Methods: A retrospective analysis was carried on the clinical data of 339 patients who underwent gynecologic laparoscopic surgery. The single factor and multiple factors Logistic regression analysis were applied to the general clinical data of patients, preoperative laboratory examination index, types of operation, intraoperative and postoperative intervention treatment. Results: Among the 339 patients who underwent gynecologic laparoscopic surgery, 30 cases had postoperative DVT(incidence about 8.8%). Such factors were positively correlated DVT as age(OR=1.438), type of surgery(laparoscopic gynecologic malignant tumor surgery)(OR=3.153), plasma D-dimer level ≥0.5 mg/L(OR=2.531), preoperative complications(OR=2. 885), intraoperative pneumoperitoneum pressure(OR=2.835), the operation time ≥1 h(OR=1.397) and days in bed after gynecological laparoscopic surgery(OR=1. 498)(P<0.05). Conclusion: Age, type of operation, the plasma D-dimer level, preoperative complications, intraoperative pneumoperitoneum pressure, operation time and postoperative days in bed were independent risk factors for the development of VDT after gynecologic laparoscopic surgery. [ABSTRACT FROM AUTHOR]

DON Toxin is a natural toxin produced by Fusarium after infecting cereals, which seriously threatens food security, food safety and human health. This paper introduces the discovery and research history of vomittin, its family (monotelomeric compounds) and typical members, and the frontier research of biological detoxification by means of personification, so that readers can understand this dangerous toxin in a lively way, especially for teachers and students of agricultural and medical colleges and universities. [ABSTRACT FROM AUTHOR]

目的探讨子宫肌瘤患者手术前后血小板、凝血功能指标的变化。方法选择2015 年1 月至2016 年 10 月于焦作市人民医院接受子宫肌瘤摘除手术患者120 例作为研究对象，将其分为开腹组和腹腔镜组，每组60 例。另 选取焦作市人民医院同期的60 例健康体检者作为对照组。观察并比较三组受试者手术前后血小板、凝血功能指标的变 化情况。结果开腹组和腹腔镜组患者术前血浆凝血酶原时间（PT）、活化的部分凝血活酶时间（APTT）、凝血酶凝结时 间（TT）、血小板计数（Plt）、D⁃二聚体（D⁃D）、血管性血友病因子（vWF）水平均高于对照组，而纤维蛋白原（FIB）、血小板 体积分布宽度（PDW）、血小板平均容积（MPV）水平均低于对照组，差异均有统计学意义（P<0.05）；开腹组和腹腔镜组患 者术毕，术后24、72 h 的FIB、PDW、MPV 水平均高于术前，且随术后时间延长呈升高趋势，而PT、APTT、TT、Plt、D⁃D、 vWF 水平均低于术前，且随术后时间延长呈降低趋势，差异均有统计学意义（P<0.05）。结论子宫肌瘤摘除手术患者 术前存在血液高凝状态，患者子宫肌瘤摘除术后血小板、凝血功能指标有所改善。 [ABSTRACT FROM AUTHOR]

Two - dimensional materials become one of the research hotspots due to the excellent optical, mechanical, thermal and magnetic properties. SnO2 film is a kind of excellent semiconductor material with high electron mobility, good conductivity and transparency. In this paper, the electronic structures, electronic state densities, electrical conductivities and optical properties of pure and doped SnO2 have been studied using the first principles of density functional theory. The calculation results show that a lot of impurity levels are generated near the Fermi level of two - dimensional SnO2 compared with three - dimensional SnO2, which improves the carrier concentration, reduces the band gap, enhances the localization of electrons, increases the effective mass of electrons in the conduction band, and facilitates the occurrence of electronic transitions, thus increasing the conductivity of materials. Two - dimensional SnO2 material has stronger electrical polarization ability than three - dimensional SnO2 material, and has better photon absorption performance and higher photoconductivity in infrared, visible and ultraviolet regions, which is more favorable for the separation and migration of photoelectron - hole pairs, that is, it can effectively improves its photoelectric conversion efficiency. Secondly, doping La can better improve the ability of absorbing photons in infrared, visible and ultraviolet regions, which is more conducive to the efficiency of photoelectric conversion and improve the conductivity. [ABSTRACT FROM AUTHOR]

Objective: To explore the relation of self-injury behavior to thyroid hormones and lipids in adolescent patients with depression. Methods: A total of 182 adolescent inpatients who met the diagnostic criteria for depression according to the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5) were enrolled, including 38 cases with self-injurious behavior and 144 cases without self-injurious. The differences in various indicators between the two groups were compared, and logistic regression analysis was used to analyze factors related to self-injury in adolescents with depression. Results: The patients with self-injurious behavior had higher levels of total cholesterol and high-density lipoprotein cholesterol (HDL-C) compared to those without self-injurious behavior (P<0.05). They also had lower levels of free thyroxine compared to the group without self-injurious behavior (P<0.05). Logistic regression analysis results showed that those with longer duration of disease (OR = 1.03) and higher HDL-C levels (OR = 12.75) were more likely to have self-injurious behaviors. Conclusion: Long duration of disease and high level of HDL-C may be risk factors for self-injurious behavior in adolescents with depression, while low level of free thyroxine may serve as a protective factor. [ABSTRACT FROM AUTHOR]

Based on the plane waveultra soft pseudopotential method of density functional theory (DFT), the electronic structures and optical properties of intrinsic AIN, CAIN, Na - AIN and C-Na- AIN were calculated. It is concluded that after doping, lattice distortion occurs in each system compared with intrinsic AIN, and the binding energy of C - Na-AIN system is the smallest and the system is the most stable. Compared with the intrinsic AIN, the band gap width of the doped system decreases to varying degrees, resulting in an increase in the probability of electron transition in the system, especially in the C-Na- AIN system, which requires less energy for electron transition. After doping, the absorption band edge has a red shift, which widens the response range of AIN system to light and enhances the light absorption. Moreover, C-Na- AIN system has the strongest light absorption ability in the visible light region. From the analysis of dielectric function diagram, it can be seen that C-Na-AIN system has the largest dielectric constant, indicating that its charge binding ability is the strongest, the stability of the system is strong, and the polarization ability is the best. [ABSTRACT FROM AUTHOR]

Based on higher agricultural and forestry education, we have explored and practiced the teaching of organic chemistry course from aspects such as teaching cases, teaching methods, and teacher team building. The teaching practice has shown that it has stimulated students’ interest in learning, broadened their horizons, and helped them appreciate the charm of frontier research in organic chemistry (especially the cross-integration with agricultural science). It has also cultivated students’ cultural literacy, professional competence, and scientific literacy, shaping their passion for agriculture and the country. The teaching approach has achieved the integration of knowledge imparting, competence development, and value-oriented guidance, effectively addressing the issue of incomplete alignment between public basic courses and professional education needs. It has fully played the role of the course in the cultivation of agricultural science talents. [ABSTRACT FROM AUTHOR]

BACKGROUND: Astrocytes are the most abundant cells in the central nervous system, and various subsets of astrocytes are heterogeneous, performing a variety of special functions. Single-cell RNA sequencing (scRNA-seq) technology developed in recent years has extended our understanding of astrocyte heterogeneity from the perspective of transcriptome profiling. OBJECTIVE: To summarize the heterogeneity of scRNA-seq technology in different time and space, and pathological states and expand our knowledge of astrocyte heterogeneity on both molecular and functional levels. METHODS: The relevant articles on astrocyte heterogeneity and scRNA-seq were searched on PubMed, Elsevier, and CNKI databases. The search terms were “astrocytes, scRNA-seq, heterogeneity, Alzheimer disease, spinal cord injury, multiple sclerosis” in Chinese and English. Finally, 74 articles were selected for viewing after screening according to inclusion criteria. RESULTS AND CONCLUSION: scRNA-seq studies related to the heterogeneity of astrocytes have shown that astrocyte is significantly heterogeneous across four aspects: species, developmental stage, central nervous system region, and pathological state. (1) Unique expression of certain genes occurs in astrocytes of different species, and the discovery of species-specific genes is beneficial for the translation of clinical studies. (2) During astrocyte development, differential gene expression emerged in the cellular subtypes identified at each stage, which further refined the cellular lineage of astrocytes and laid the foundation for the study of astrocyte developmental trajectories and mechanisms. (3) The discovery of differential gene expression allows regional localization of different astrocyte subpopulations and assists in the diagnosis and treatment of neurological diseases. (4) Astrocyte heterogeneity revealed by scRNA-seq can provide specific markers at the time of disease diagnosis and identify potential therapeutic targets. (5) The heterogeneity of astrocytes exists in many aspects, interacts with each other and is complex. The mechanisms of its generation, maintenance and transformation remain unclear. At present, molecular research on the single-cell level is still lacking. Linking transcriptionally defined astrocyte subpopulations to cellular activity, behavior and disease markers in real time remains one of the great challenges in the field. [ABSTRACT FROM AUTHOR]

[Abstract] Objective: To understand the basic information such as age, job title, and education of rehabilitation therapists in the Grade III public psychiatric hospitals in China, and provide fundamental data for the construction of the mental health rehabilitation talent team. Methods: The staffing of rehabilitation therapists in 43 Grade III public psychiatric hospitals in eastern, central, and western regions of China were investigated. The age, education, job title, professional relevance and inter-regional differences of the rehabilitation therapists were statistically analyzed. Results: There were 197 rehabilitation therapists in 43 hospitals surveyed. The age distribution was mainly in 20-30 and 30-40 years old with a bachelor's degree and junior, and more than half of the personnel had their first academy degree related to the rehabilitation profession. The differences in age, education, job title were statistically significant in the eastern, central and western regions. Conclusion: The overall quality of the rehabilitation therapists in China's Grade III public psychiatric hospitals is relatively high, and the age structure is reasonable. However, the proportion of senior professional titles is relatively low. Therefore, it is necessary to focus on talent training and the establishment of promotion systems in the future, in order to improve the professional development space and level of the entire industry. [ABSTRACT FROM AUTHOR]

Based on the first principle method of density functional theory, this paper studies the stabilities, electronic structures, and optical properties of Sc, C single doped and co-doped MgS systems. The results show that compared with the intrinsic MgS system, the binding energy of the doped system is still negative, indicating that the doped systems are in a stable state. Among them, the binding energy of Sc-C co-doped MgS system is the smallest, indicating that Sc-C co-doped system is the most stable. After doping, the band gap width of the system decreases, indicating that the energy of electron transition from valence band to conduction band decreases. In addition, the doping system has an obvious red shift in the low-energy region, indicating that Sc and C doping can effectively broaden the response range of the system to visible light. Among them, Sc-C-MgS system produces impurity levels near the Fermi level, and the band gap width is small. The absorption coefficient is the best in the visible light range. It can be inferred that Sc-C co-doping can be used as an effective means to improve the photocatalytic activity of MgS system. [ABSTRACT FROM AUTHOR]

Type 2 diabetes is a high risk factor for atherosclerotic cardiovascular disease. Studies have found that SGLT-2 inhibitor and GLP-1 receptor agonists have cardiovascular protective effects in patients with type 2 diabetes and cardiovascular disease. Therefore, from the aspects of cardiovascular safety test and its Meta-analysis and net-like Meta-analysis, the research progress of cardiovascular safety of SGLT-2 inhibitors and GLP-1 receptor agonists is summarized. [ABSTRACT FROM AUTHOR]

In this paper, the electronic structure and magnetic properties of SnO2 doped with non-metallic elements (N) and transition metal elements (Mo, Ru, Rh, Pd) are calculated and analyzed based on the first principles approach. The results show that: the formation energy is closely related to the transition metal atomic radius, with the increase of the transition metal atomic radius, the formation energy is decreasing, where the N-Mo doping system has the lowest formation energy, so the system is the easiest to doping formation; energy band structure analysis shows that due to the number and distribution of spin up/spin down impurity energy levels of the doping system are asymmetric, the doping systems are magnetic generation; further exploration of the density of states shows that The magnetic properties of the doped system are due to the p-d orbital hybridisation between the transition metal atoms and the N atoms, the vacancies in the outermost electron orbitals and the single electron coupling. The results show that the SnO2 system is magnetic due to the introduction of doping atoms, and the doped system exhibits subferromagnetic properties, with the best magnetic moment of 1.88 μB for the N-Rh doped system, which is expected to be a good dilute magnetic semiconductor material. [ABSTRACT FROM AUTHOR]

Objective: To explore the effect of strengths-based cognitive behavioral therapy (SBCBT) model on hope in adolescents with depression. Methods: Totally 89 adolescents with depression meeting the diagnostic criteria for mild and moderate depressive episodes of the International Statistical Classification of Diseases and Related Health Problems, Tenth Revision (ICD-10) were randomly divided into the combined treatment group (n=44) and the sertraline group (n=45). The combined treatment group received 8 times of SBCBT intervention on the basis of the sertraline group. The Adult Dispositional Hope Scale (ADHS), Hamilton Depression Scale-17 (HAMD-17) and Hamilton Anxiety Scale (HAMA) were measured at base-line and 6 weeks after intervention. Results: After 6-week intervention, the ADHS total scores in both groups were higher than the baseline (P <0.001), and the total scores of HAM D-17 and HAMA in both groups were lower than the baseline (P <0.001). The ADHS total scores were higher and the total scores of HAMD-17 and HAMA were lower in the combined treatment group than in the sertraline group (P<0.001). Correlation analysis showed that the total score difference of ADHS was positively correlated with the total score difference of HAMD-17 (r=0. 46, P <0.001) and the total score difference of HAMA (r = 0.29, P <0.01). Conclusion: It suggests that SBCBT is beneficial to improve depression, and enhance the hope of adolescent patients with depression. [ABSTRACT FROM AUTHOR]

In view of the low efficiency of financing of listed companies in China’s textile industry, with the impact of the new economic norm, DEA model is used to evaluate the financing efficiency of the 15 domestic textile listed companies. The study shows that the scale of assets and asset liability ratio is smaller, the financing efficiency is high. Under the new economic norm of the economic slowdown indirectly leads to low efficiency of financing. Financing efficiency and level of main business income is not necessarily linked. [ABSTRACT FROM AUTHOR]

Objective: To study the effect of autonomic nerve denervation on long-term efficaey of CPVA in atrial fibrillation patients. Methods: 104 consecutive paroxysmal AF(PAF) patients with symptomatic and drug refractory AF were enrolled in this study.All patients underwent CPVA. During follow-up,24 hour Holter monitoring was performed before and after procedure. Then the patients accepted Holter examination every 3 months. Free of atrial tachyarrhythmias(>30sec) during follow-up was regarded as no recurrence.Autonomic nerve denervation was assessed by heart rate variability(HRV) from Holter. Results: 104 patients finished the study.According to the outcome, the average operation time is(1.35 ±0.65), the overall cumulative success rate was 77.9 %, the time of follow-up is(24.27±11.13)-month. All patients were divided into success group(81 cases) and recurrence group(23 cases). After CPVA HRV decreased signiflcantly in each group. Furthermore,the characters of SDNN, r MSSD, PNN50, TF, VLF, LF and HF of success group were significantly lower than those of recurrence group(P<0.05). Conclusions: CPVA is an effective therapy for PAF, CPVA could induce autonomic nerve denervation, which may contribute to the long-term success of AF ablation. [ABSTRACT FROM AUTHOR]

The electronic structure, magnetic properties and optical properties of anatase TiO2 and Cr doped anatase TiO2 ( 1/8, 1/16, 1/32) were studied by first principles GGA + U method. The calculation results show that the binding energy of Ti 0. 9375 Cr0. 0625 O2 is the smallest in all doping systems. Therefore, the stability of Ti 0. 9375 Cr0. 0625 O2 system is higher than that of Ti0. 875 Cr0. 125 O2 and Ti0. 96875 Cr0. 03125 O2, the doping of Cr leads to lattice distortion, which is beneficial to the separation of photogenerated holes and electron pairs, and improves the photocatalytic performance. At the same time, because of the interaction of Cr - 3d and 0 - 2p electrons, the doped system presents ferromagnetic properties, and with the increase of doping concentration, the system will have better ferromagnetic properties. Compared with the intrinsic TiO2, the absorption band edge of the doped system is red shifted and the spectral response range is enlarged, Moreover, with the increase of doping concentration, the light response range also increases, which effectively enhances the absorption ability of the system for visible light. [ABSTRACT FROM AUTHOR]

Technological innovation is the key to driving the development of regional circular economy and plays an important role in the realization of regional sustainable development and the construction of ecological civilization. The study analyzed the spatial and temporal evolution characteristics of circular economy performance in 30 provinces and municipalities in China by constructing an evaluation system based on the ecological efficiency model and examined the spatial effect of technological innovation-driven regional circular economy performance by using spatial panel data regression methods. The study reached the following conclusions: ① Resource efficiency, environmental efficiency, and circular economy performance were on the rise in the time series. The average annual growth rates of the three were 1.14%, 1.03%, and 1.24%, respectively, showing a gradual decrease in space from the eastern region to the central and western regions. The global Moran' s I index increased from 0.2004 to 0.3629. The circular economy performance and subsystems showed obvious clustering distribution characteristics, and the regional differences were constantly shrinking. ② From the perspective of the comprehensive effect of the impact, talent support and technological achievements had a promoting effect on the improvement of regional circular economy performance. R&D investment had a restraining effect. Among the control variables, industrial structure and FDI had a positive impact on regional circular economy performance, and environmental regulations had a negative impact. The impact of urbanization was not obvious. ③ From the perspective of the decomposition effect of impact, the direct effect of talent support and technological achievements was positive, while the indirect effect was negative. The direct effect of capital investment was significantly negative. In terms of control variables, the direct and indirect effects of FDI were both significantly positive. The direct effects of industrial structure and the indirect effects of urbanization were positively related to the performance of the regional circular economy, and the impact of environmental regulations was not obvious. ④ This study puts forward countermeasures and suggestions for improving the strength of regional green technology innovation and building a green technology innovation system. The research has certain reference values for promoting the improvement of regional circular economy performance and the construction of national and regional ecological civilization and green development. [ABSTRACT FROM AUTHOR]

In this paper, the effects of F, S, Se and Te doping on the interfacial interaction and electronic structure of ZnO/graphene heterojunctions were systematically studied based on first-principles. The results show that the ZnO/graphene heterojunction layers are bonded by van der Waals force to form a stable heterojunction and an n-type Schottky barrier. The differential charge density diagram shows that the electrons of the graphene layer transfer to the ZnO layer, making the surface of the graphene layer positively charged and the surface of the ZnO layer negatively charged, forming a built-in electric field at the interface. When F atoms are added, the heterojunction presents ohmic contact. When S, Se and Te atoms are added, the contact types of the heterojunction Schottky change from n type to p type, and the height of the Schottky barrier effectively reduces, especially after Te atom is added, the height of the p type Schottky barrier reduces to 0. 48 eV, which improves the electron injection efficiency. The research results of this paper will provide reference for the design and manufacture of related. [ABSTRACT FROM AUTHOR]

The stability, electronic structures, work function, and optical properties of single-layer g-C3N4 and X/ g-C3N4 (X = g-C3 N4 , AlN and GaN) heterostructures were investigated using plane-wave density functional theory with ultra-soft pseudopotentials. The results show that the lattice mismatch ratio and lattice mismatch energy of X/ g-C3N4 heterojunction are very low, indicating that X/ g-C3N4 heterojunction has excellent stability. Compared with the single-layer g-C3N4, the bandgap of the X/ g-C3N4 all reduces, and the peaks and troughs of the density of states greatly improves. At the same time, X/ g-C3N4 has a redshift, which leds to an increase in the number of electrons in the excited state, making electronic transitions easier. It shows that the heterojunction is beneficial to improves the response-ability of the system to visible light, and effectively improves the photocatalytic activity of the system. Further calculations show that the work function of X/ g-C3N4 reduces and a built-in electric field is formed at the interface, which inhibits the recombination of photo-generated electron-hole pairs. This is of great benefit to the migration of carriers and the improvement of photocatalytic ability. Among them, the GaN/ g-C3 N4 heterojunction has the smallest work function, the potential difference at the interface formed a built-in electric field and the redshift is the most obvious. It can be inferred that the GaN/ g-C3 N4 heterojunction has the best photocatalytic activity. Therefore, the heterojunction proposed in this paper is an effective means to improve the photocatalytic activity of the system. [ABSTRACT FROM AUTHOR]

目的 总结伴有先天性巨结肠的 Rubinstein-Taybi综合征 (Rubinstein-Taybi syndrome, RSTS) 的有效诊断 方法. 方法 对1例伴有先天性巨结肠的 RSTS 患儿的诊断过程作回顾性分析. 结果 患儿, 男, 主要临床表现为 先天性巨结肠, 颅面畸形, 漏斗胸, 双侧拇指及踇趾宽大, 伴有生长迟滞, 智力及运动发育迟缓. 患儿行全结肠切除 术, 术中行腹直肌肌肉组织活检可见单个和成簇萎缩肌纤维, 部分肌纤维肌膜下或胞质存在单个或多个大小不等空 泡, 术后病理组织检查可见全结肠肠壁充血, 水肿, 黏膜下及肌间见神经节细胞, 发育不良, 并见较多粗大神经纤维, 部分肠壁纤维增生. 术后考虑患儿存在肌源性损伤. 为明确病因, 对患儿腹直肌肌肉组织进行全外显子 (含线粒 体) 组基因测序, 结果显示患儿 16号染色体 CREBBP 基因外显子 c. 2911A>G (p. R971G) 杂合突变. 结合患儿临床 表现, 明确诊断为RSTS. 结论 RSTS 患儿主要临床表现为先天性巨结肠, 颅面畸形, 双侧拇指及踇趾宽大, 生长迟 滞及智力及运动发育迟缓, 在16号染色体CREBBP基因外显子存在c. 2911A>G (p. R971G) 杂合突变. 临床表现结 合CREBBP基因突变可明确 RTST 诊断. [ABSTRACT FROM AUTHOR]

[Objective] The aim was to explore the variation of appearance quality traits of early generation scented lines of japonica aromatic rice by two methods of hybrid breeding and radiation mutation breeding, and explore the selection of appearance quality traits of scented offspring. [Method] The F2 generation population of the fragrant rice variety Yanjing 939, the non-scented rice variety Fuxiang, and the M2 generation population of the fragrant rice variety Yanjing 939 60 Co-γ irradiated with Co-γ rays were used as the research materials. Carry out the analysis of scent traits and appearance quality traits. [Results] The aroma of Yanjing939 was controlled by a pair of recessive genes. The aroma strains in the F2 population of Yanjing939 ×Fuxiang accounted for 25.7% of the total population. The aromatic strains in the M2 population induced by radiation of Yanjing939 accounted for 64.5% of the total population. In terms of grain length, grain width, grain thickness, transparency, chalky grain rate, and chalkiness traits, the coefficient of variation and diversity index of fragrance plants in the F2 population ranged from 3.45% to 90.81%, 0.343 to 0.457, and the average values ​​were respectively It is 28.28% and 0.426. The coefficient of variation and diversity index of fragrance strains in the M2 population were 2.66%-81.36% and 0.389-0.438, with the average values ​​being 27.80% and 0.409, respectively. Principal component analysis showed that, compared with M2 generation fragrance strains, the appearance quality traits of F2 generation fragrance strains were quite different. The canonical correlation analysis shows that the aromatic strains can achieve the purpose of improving chalkiness and transparency through comprehensive selection of grain types. [Conclusion] Hybrid breeding and radiation mutagenesis have different characteristics in the selection of scented rice varieties. The appearance quality traits of early generation scented lines of hybridization and radiation mutagenesis show corresponding changing trends under the influence of their parents. The results can provide a basis for the selection of breeding methods and the improvement of appearance quality traits in the selection and breeding of fragrant rice varieties. [ABSTRACT FROM AUTHOR]

Objective To analyze the relationship between sclerostin and cardiovascular risk factors in middle-aged and elderly men with normal blood glucose in Beijing. Methods One hundred and five men (40-69 years old) with normal glucose metabolism were screened from a cross-sectional survey of middle-aged and elderly population in a community in Beijing. Age, smoking and drinking history, history of past illness, and other information were collected. Body mass index (BMI), waist circumference, and blood pressure were measured. Blood glucose and blood lipids were tested. Serum sclerostin level was determined using enzyme-linked immunosorbent assay (ELISA). Results 1) The level of sclerostin was statistically different among subjects of different age and BMI (P < 0. 05). 2) There was a correlation between age, BMI, and sclerostin. 3) The multivariate linear regression analysis showed that sclerostin was significantly correlated with age and BMI. Conclusion Among many cardiovascular risk factors, age and BMI were positively correlated with the level of sclerostin. [ABSTRACT FROM AUTHOR]

Objective To establish an assay method for unbound teicoplanin in plasma by centrifugal ultrafiltration combined with ultra-performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS). Methods Protein was removed from plasma by a Centrifree® ultrafiltration device. The ultrafiltrate was injected to determine the unbound concentration of teicoplanin. EndeadvorsilTM C18 column (1.8 μm, 50 mm×2.1 mm) was used with gradient elution of acetonitrile and 0.02 mol/L ammonium acetate solution (containing 0.1% formic acid). The detection was performed on a triple-quadrupole tandem mass spectrometer by multiple reaction monitoring (MRM)mode via electro spray ionization (ESI). Results The calibration curve of unbound teicoplanin in plasma was linear over the range of 0.10 to 8.00 μg/ml (r=0.999). The intra-assay precision and the inter-assay precision of samples didn't exceed 7.00%. The average relative recovery ratio was 97.9%, and the matrix effect factor was 0.97. The samples had good stability after being stored at room temperature for 10 h or at −20 ℃ for 15 days, and freeze-thawed 3 times (RSDs were all within 6.50%). Conclusion This method is convenient, fast, sensitive and accurate. It provided a basis for clinical development of teicoplanin unbound concentration monitoring. [ABSTRACT FROM AUTHOR]

Objective: To investigate the curative effect of plasma radiofrequency catheter ablation on adenoid hypertrophy in children and its effect on ventilatory function and inflammatory response. Methods: 100 cases of adenoid hypertrophy in our hospital from December 2016 to August 2017 were selected, 50 cases patienta treated with surgical treatment was in plasma group, and 50 patients treated with conservative treatment were in control group in the same period. The control group was given montelukast and Mumetasone furfurfurate nasal spray, and the plasma group was given low temperature plasma radiofrequency ablation. The symptom score, ventilation function and inflammatory cytokines levels in two groups before and after treatment were compared. Results: Before treatment, symptom score, apnea hypopnea index (АШ), longest apnea time (LAT), oxygen reduction index (ODI), minimum nocturnal oximetry Lowest nocturnal oxygen saturation (LSa02), percentage of time when oxygen saturation less than 90% (SLT 90%), and serum inflammatory mediators (TNF-a), interleukin-4 (IL-4) and eosinophil cationic protein (ECP) levels were not significantly different between the two groups (P>0.05). After treatment, the scores of snoring, nasal obstruction and mouth breathing were significantly decreased in both groups (P<0.05), and the scores of snoring, nasal obstruction and mouth breathing in plasma group were significantly lower than those in control group (P<0.05). After treatment, the levels of АШ, LAT, ODI and SLT90 % in both groups were significantly decreased (P<0.05), and the LSa02 level was significantly increased (P<0.05). After treatment, the levels of АШ, LAT, ODI, SLT90 % in the plasma group were significantly lower than those in the control group (P<0.05), and the LSa02 level was significantly higher than the control group (P<0.05). Conclusion: Low-temperature plasma radiofrequency ablation can significantly relieve the clinical symptoms of children, improve the body's ventilatory function and reduce the inflammatory response. [ABSTRACT FROM AUTHOR]

For many years, farmers adopt a traditional cultivation method (turning, rotating, hallowing, pressing) to grow crops in China. However, improper mechanization, the nonstandard deep tillage or illogical methods of rotary tillage and subsoiling result in soil compaction, loss of soil and the plow pan formation. Consequently, the depth of tillage is shallowing, the ability of moisture conservation is weakening, and surface runoff is increasing. Improper soil tillage methods deteriorate soil quality, affect the roots to penetrate lower soil layer, limit the potential of soil production and restrain the development of modern agriculture. How to improve the production capacity of tillage soil through mechanization becomes a valuable research project, from which a better soil tillage method needs to be developed in order to improve soil properties. However, a completed technological system for subsoiling was not yet built to achieve such goal. To improve soil tillage, field experiments (block-tillage comparison) were conducted to study the effect of deep tillage mechanically on the growth of sugar beet and soybean with the help of self-developed deep pine plough (ES-210, tillage depth 40 cm) and the subsoil tillage plough (tillage depth 20 cm). Deep pine plough was used to move subsoil (20 - 30 cm) up to the soil layer (10 - 20 cm) to form a hole. At the same time, some upper soil fell in the hole becoming fertilizer grooves. These grooves allowed deep growing of roots, conserving water and promoting fertilizer use by plants. The wide head of the plow (subsoil tillage plough) can break the plow-pan to subsoil layer down to 35 - 40 cm deep. A comparison test was carried out with the conventional tillage (stubble chopping). Results showed that the cultivation measures improved the physical quality of the soil. Compared with the conventional tillage treatment, the solid phase ratio respectively decreased by 1.6% - 3.3% and 2.8% - 4.5% with deep loosening and subsoil tillage treatments. In the meanwhile, liquid phase and vapor phase increased, resulting rationalization of three phase ratio of soil. At the same time, plough pans were broken and hardness of the soil layer was reduced. For the soil depth of 20 - 35 cm, this was more obvious. Simultaneously, soil available water of top soil increased by 1.1% - 1.2% and 0.9% for deep loosening and subsoil tillage, respectively. The irreducible water (ineffective water) decreased by 0.4%-1.1% and 0.5% - 0.9%, respectively for the two tillage treatments. Compared with the conventional tillage treatment, deep loosening and subsoil tillage treatments promoted root growth and facilitated the accumulation of plant dry matter. The root growth increased by 5.1% and 2.9% of sugar beet, 11.5% and 13.2% of soybean for deep loosening and subsoiling, respectively.Dry matter accumulation increased by 2.3% - 4.1% and 3.1%-4.8% of sugar beet, 7.8% - 10.0% and 10.4% - 13.6% of soybean, respectively for two deep tillage treatments. Mechanized soil improvement technology both increased crop production and farmers’ income. For those deep loosening and subsoiling treatments, sugar beets yield increased by 8.5% and 12.6%, and soybean yield increased by 5.0% and 6.1%, respectively. Compared with the conventional tillage treatment, deep loosening and subsoil tillage increased the income by 1003.3 and 1454.4 yuan/hm2, and profit ratio was subsoil tillage > deep loosening > conventional tillage. Hence, two kinds of tillage measures improved the soil structure of arable layer, enlarged compatibilizing effect, improved root growth environment and crop yields. The research results provided the technical support for the future of farming machinery research. It provided scientific evidence to expand this technology. [ABSTRACT FROM AUTHOR]

In this paper, the poplar wood flour/ polylactic acid composite materials was prepared and then printed by Fused Deposition Modeling (FDM). The types of elastomers on the mechanical properties and rheological properties of the composite were studied, and the advantages and problems in the process of printing using the composites were explored. Results showed that the addition of polycaprolactone(PCL) and thermoplastic polyurethane(TPU) can improve the impact strength of the composites, but the tensile strength and flexural strength reduced. Rheological results showed that a negative correlation between complex viscosity and frequency, and there was a shear-shinning phenomenon. With the addition of the elastomers, the complex viscosity, storage modulus and loss modulus of the composites increased. The addition of PCL was effective in the mechanical properties and toughness of the composites. After analyzing the error of the samples, the results showed that the error was small in XY direction. The max bevel angle that can be printed was infinitely approached arctan(layer thickness/filament diameter), so it can achieve the high precision mortise and tenon connection and the complex hollowed-out structure. [ABSTRACT FROM AUTHOR]

Objective: To investigate the application value of meglumine cyclic adenylate and perindopril in patients with chronic congestive heart failure(CCHF) Methods: 90 cases of patients with CCHF in our hospital from January 2013 to December 2015 were divided into control group, perindopril group and union group, 30 cases in each group. Patients in the control group were treated with conventional methods, patients in the perindopril group were treated with conventional methods and perindopril, and patients in the union group were treated with meglumine cyclic adenylate based on the treatment method of perindopril group. The treatment time of three groups were 2 weeks. Compared the clinical effect, LVEDD, LVESD, LVEF, 6-minute walk distance and plasma levels of BNP, IGF-1, Cys-C between three groups. Results: After treatment, the clinical effect of the perindopril group (86.67% )and union group (96.67%) were significantly higher than that of the control group (66.67%)(P<0.05); LVEDD, LVESD, and plasma levels of BNP and Cys-C of three groups after treatment were all significantly lower than before treatment (P>0.05), and the perindopril group and union group were all significantly lower than that of the control group(P<0.05); LVEDD and plasma levels of BNP ofunion group were significantly higher than that of the perindopril group (P<0.05), and the perindopril group were all significantly higher than that of the union group (P<0.05). Conclusion: The clinical effect of meglumine cyclic adenylate and perindopril in patients with CCHF are remarkable, and meglumine cyclic adenylate can improve the effect of perindopril on left ventricular remodeling situation, left ventricular function, and patients' activity, and those may be related with modify the plasma levels of BNP, IGF-1, Cys-C. [ABSTRACT FROM AUTHOR]

Objective To investigate the relationship among muscle strength, fall risk, and vitamin D (VD) status in the middle-aged and elderly males. Methods A cross-sectional survey was designed. Changes of VD with age and its relationship with muscle strength and fall risk were observed. Results The VD deficiency rate accounted for 77.41%, including 7.83% serious deficiency in the group. With the increase of age, the grip and pinch strength and muscle strength of the lower limbs decreased gradually. The time of get-up and go test (TGUT) and chair rising test (CRT) increased. After adjusting milk intake, sunshine duration, exercise frequency, and working environment, there was no significant difference in the level of VD among groups by age. Grip and pinch strength decreased in serious VD deficiency group. After adjusting age, the difference of serum calcium, grip and pinch strength, and muscle strength of the lower limbs among groups was significant. And the lowest level was found in the serious VD deficiency group. In the over 60 years old group, CRT time was the longest in VD deficient group, but TGUT was not statistically different among different groups by VD level and among subgroups by age. Multiple logistic regression analysis showed that increasing age and decreased strength of grip were independent factors of VD deficiency, with the OR values of 1.37 and 1.33, respectively. Conclusion Proportion of VD deficiency is higher in men over 40 years old. With age increasing, the fall risk increases. Increase of age and decrease of muscle strength of the upper limbs are independent influence factors of VD deficiency. [ABSTRACT FROM AUTHOR]

Objective: To explore the effect of letrozole combined with metformin in the treatment of infertility with polycystic ovary syndrome (PCOS). Methods: Selected 150 infertile women with PCOS who were treated in our hospital from June 2012 to June2013, they were randomly divided into study group and control group with 75 patients in each group. The control group was only treated with letrozole ovulation therapy, while the study group was treated with letrozole combined with metformin therapy. Observed the glycometabolism indexes, curative effect and ovulation outcome in two groups before and after treatment. Results: Fasting blood glucose,fasting insulin, insulin resistance (insulin resistance, IR) in two groups before treatment had no significant difference (P>0.05); Above indexes in study group after treatment were significantly decreased than before treatment, which were significantly lower than the control group after treatment (P<0.05). Ovulation amount, dominant follicle amount of study groups was significantly more than control group (P<0.05), and the follicular growth time was significantly shorter than control group (P<0.05). The pregnancy rate in study group was60.00%, which was significantly higher than 33.33% in control group (P<0.05). Conclusion: Letrozole combined with metformin is not only has a exact curative effect in the treatment of infertility with PCOS, but also can effectively reduce the androgen level,increase the ovulation amount and dominant follicle amount, which can improve the life and pregnancy quality of the infertility. [ABSTRACT FROM AUTHOR]