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Objective To evaluate the safety, effectiveness and feasibility of robotic-assisted kidney transplantation (RAKT). Methods Clinical data of 16 patients who underwent kidney transplantation were collected. Among them, 8 recipients received RAKT (RAKT group) and 8 cases underwent open kidney transplantation (OKT) with the contralateral kidney from the same donor (OKT group). Perioperative status and the recovery of renal allograft function were compared between two groups. Results All patients successfully completed the surgery. In the RAKT group, no patient was converted to open surgery. The operation time in the RAKT group was longer than that in the OKT group (P=0.015). No significant differences were observed in the serum creatinine levels before surgery and upon discharge between two groups (both P>0.05). In the OKT group, one recipient developed delayed graft function (DGF), and the remaining recipients did not experience perioperative complications. No significant difference was noted in the short-term recovery of renal allograft function between two groups (P>0.05). Conclusions Postoperative recovery of the recipients in the RAKT group is equivalent to that of their counterparts in the OKT group. RAKT is a safe and effective procedure for the team expertise in kidney transplantation. [ABSTRACT FROM AUTHOR]

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Objective To explore the effects of ginsenoside Rg1 （ginsenoside Rg1） on cell apoptosis， oxidative stress and inflammation in young rats with hypoxic-ischemic brain damage （HIBD）.Methods Young Wistar rats were divided into healthy control group， model group （HIBD）， and HIBD+ginsenoside Rg1 group. Jumping test was used to detect the number of mistakes in each group of rats， brain tissue wet and dry weight method was used to calculate the brain water content and brain index of each group of rats. Hematoxylin-eosin （HE） staining was used to observe the degree of brain damage； TUNEL staining to observe the apoptosis level of brain tissue； Nissl body staining to detect neuronal cell apoptosis； Western blot to detect brain tissue Bax/Bcl-2， caspase-3， caspase-9 protein expressions； malondialdehyde （MDA） and superoxide dismutase （SOD） activity detection kit to detect MDA and SOD content， respectively； and ELISA to detect peripheral blood IL-6， iNOS， IL-4 contents. Results Compared with the model group， 20 mg/kg and 40 mg/kg ginsenoside Rg1 significantly reduced the number of mistakes in the jumping-off test of HIBD young rats， and brain index brain water rate and neuronal cell apoptosis （P<0.05）； alleviated brain tissue damage； down-regulated the protein expression levels of Bax/Bcl-2， cleaved cas9/cas9 and cleaved cas3/cas3 （P<0.05）； reduced IL-6 and iNOS protein content； and increased IL-4 protein content （P<0.05）.Conclusion Ginsenoside Rg1 improves brain tissue damage in young HIBD mice and inhibits neuronal cell apoptosis. [ABSTRACT FROM AUTHOR]

目的观察吗啡联合氯胺酮治疗晚期癌症疼痛（癌痛&的临床疗效及安全性。方法选取2014年4月至 2016年4月温州市中心医院及温州医科大学附属第一医院收治的已确诊晚期癌痛患者62例，分别为13(49例，随机分 为对照组（30例）和观察组（32例&。两组均采用蛛网膜下腔持续静脉泵入方法控制癌痛，其中观察组给予5 mg氟哌利 多+100mg吗啡+50mg氯胺酮+100mL生理盐水治疗，对照组給予5 mg氟哌利多+100mg吗啡+100mL生理盐水治疗。治 疗后30min, 1、5、24、48h对两组患者视觉模拟评分法（VAS)评分、生活质量、不良反应情况进行对比。结果治疗后两组 疼痛均有明显缓解，同时两组治疗后各时间点VAS评分与治疗前比较，差异均有统计学意义(P<0.05);而两组治疗后各时 间点VAS比较，差异均无统计学意义(P>0.05);在生活质量评分方面，观察组明显低于对照组，差异有统计学意义(P<0.05); 在不良反应方面，观察组恶心呕吐、便秘、头晕、嗜睡等发生率明显低于对照组，差异有统计学意义（P<0.05)，但两组均无 呼吸抑制和幻觉发生。结论蛛网膜下腔鞘内持续静脉泵入吗啡联合氯胺酮有一定的镇痛作用，不良反应小，适用于治 疗晚期难治性癌症疼痛。 [ABSTRACT FROM AUTHOR]