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面向不断涌现的新型应用和业务需求，空天地海一体化网络具有全域覆盖、高效灵活、弹性可靠等优势，为众多领域的多样化业务场景提供智能、协同、高效的泛在信息服务，是未来移动通信系统的重要组成部分。首先，分析了空天地海一体化的国内外发展现状、网络架构及其面临的需求挑战；然后，以海量差异化业务的承载需求为驱动力，研究了网络切片、移动边缘计算、通感算一体化关键网络技术；最后，从智能化、融合化、安全化角度探讨了未来空天地海一体化发展方向。

Neutrophils are one of the important components of the tumor microenvironment. Neutrophil extra cellular traps (NETs) are a network structure released by neutrophils, and their formation process is called neutrophil inflammatory apoptosis (NETosis). Neutrophils in the tumor microenvironment, also known as tumor associated neutrophils (TANs). TANs including N1 phenotype and N2 phenotype have a bidirectional regulatory effect on tumors. While N1 phenotype inhibits tumor growth, and N2 phenotype promotes tumor growth, and N1 and N2 types undergo mutual transformation due to the influence of the tumor microenvironment. Neutrophils and NETs also play important roles in bone and osteosarcoma tissue sarcoma, which can affect tumor progression and predict patient prognosis. Blocking the formation of NETs may be a potential therapeutic target. [ABSTRACT FROM AUTHOR]

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The choice of catalyst combinations involved in the chemical industry has a huge impact on the product yield. In order to better investigate the selection of the appropriate catalyst optimization combination in the teaching experiments for the preparation of C4 olefins by catalytic coupling of ethanol, a catalyst combination selection model was developed based on correlation coefficient analysis, gray correlation analysis, stepwise regression idea and generalized global optimization algorithm. The model considered temperature, Co loading rate, hydroxyapatite (HAP), Co / SiO2 and HAP loading ratio. Based on the actual production experimental data, the catalyst combination that maximizes the ethanol conversion and C4 olefin yield under certain conditions was obtained by applying generalized traversal priority search, least squares and optimization model. It was shown that the C4 olefin yields are 46. 78% and 40. 44% for the two loading methods without limiting the upper temperature limit, respectively. At the limiting temperature limit of 350 ℃, the C4 olefin yields were 19. 80% and 5. 77%, respectively. [ABSTRACT FROM AUTHOR]

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Objective To assess the efficacy of high-pressure balloon dilation of ureterovesical junction for primary obstructive megaureter in children. Methods A total of 19 children with primary obstructive megaureter underwent high-pressure balloon dilation under general anesthesia from January 2015 to December 2020.Results Significant postoperative improvement of hydroureteronephrosis were noted in 12 cases after single treatment, 5 children achieved cure after a second treatment and another 2 underwent ureteral bladder reimplantation after a failure of dilation. Insertion of guide wire failed in one case while another child showed no improvement after a second dilation. At 6 months post-operation, radionuclide imaging indicated improvements of renal function and hydroureteronephrosis in 17 children after dilation. During an average follow-up period of 14(7-26) months, there was no sign of recurrence. Conclusion High-pressure balloon dilation of ureterovesical junction is both safe and effective for primary obstructive megaureter in children. [ABSTRACT FROM AUTHOR]