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Copyright of Plastics Science & Technology / Suliao Ke-Ji is the property of Plastics Science & Technology Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Chinese Journal of Tissue Engineering Research / Zhongguo Zuzhi Gongcheng Yanjiu is the property of Chinese Journal of Tissue Engineering Research and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Advanced Engineering Science / Gongcheng Kexue Yu Jishu is the property of Advanced Engineering Science Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objective: Screening for molecular markers of lung cancer proteins to find protein markers that can diagnose and predict the prognosis of lung cancer. Methods: Eighty patients with NSCLC diagnosed in the Fourth Hospital of Xi'an from August 2014 to July 2019 and undergoing lung resection were selected, IHC was used to detect the positive rate of MCM2, MCM5, MCM6, MCM7, KIAA1522 and KIAA0317, to explore the clinical value of combined detection of multiple proteins in the diagnosis and prognosis prediction of NSCLC. Results: The positive rates of MCM2, MCM5, MCM6, MCM7, KIAA1522 and KIAA0317 in lung cancer tissues were significantly higher than normal tissues adjacent to cancer (P<0.05), of which MCM6, MCM7 and KIAA1522 were more than 50 %. In the joint detection of lung cancer tissues, there was no statistically significant difference in the combined protein positive rate of NSCLC patients of different genders, different ages, types and stages (P>0.05), and the protein positive rate was more than 80%; MCM7 high expression was lower than low expression or not The expressed cases significantly increased the patient's risk of death (P=0.000). Males (P=0.031), patients with stage III to IV (P<0.001), and poor differentiation (P=0.012) are also the poor prognostic factors of patients. Multivariate regression analysis shows that MCM7 is an independent predictor (P=0.000), which has a significant correlation with the survival of patients and has a certain predictive effect on prognosis. Conclusion: MCL6, MCM7 and KIAA1522 are highly expressed in lung cancer tissues of NSCLC patients. The combined detection of the three has high accuracy, sensitivity and specificity for the detection of NSCLC. The high level of MCM7 expression indicates poor prognosis of lung cancer patients. [ABSTRACT FROM AUTHOR]

Objective: To study the expression and clinical significance of serum matrix metalloproteinase-9 (MMP-9), tissue inhibitor of metalloproteinase-1 (TIMP-1), tumor necrosis factor -琢 (TNF-琢) and interleukin-10 (IL-10) in premature parturients with preterm premature rupture of membranes. Methods: 58 cases of premature parturients with preterm premature rupture of membranes who were treated in our hospital from May 2016 to September 2017 were selected as the study group, 58 full-term parturients who underwent cesarean section in our hospital in the same period were selected as control group in addition. The serum levels of MMP-9, TIMP-1, TNF-琢 and IL-10 were compared between the two groups, the study group were divided into subgroup with chorioamnionitis (n=30) and subgroup without chorioamnionitis(n=28) according to the results of fetal membrane and placenta pathology, the serum levels of MMP-9, TIMP-1, TNF-琢 and IL-10 in both subgroups were compared. Pregnancy outcomes in the study group and control group were recorded. Results: The levels of serum MMP-9 and TNF-琢 in the study group were higher than those of the control group, while the level of TIMP-1 and IL-10 were lower than that of the control group (All P<0.05). The serum levels of MMP-9 and TNF-琢 in subgroup with chorioamnionitis were higher than those of subgroup without chorioamnionitis, the TIMP-1 and IL-10 level was lower than that of subgroup without chorioamnionitis (All P<0.05). The incidence of cesarean section, postpartum hemorrhage, neonatal pneumonia in the study group were all higher than those in the control group, the Apgar score of newborn was lower than that of the control group (All P<0.05). Results: Abnormal elevation of serum MMP-9 and TNF-琢 in premature parturients with preterm premature rupture of membranes, TIMP-1 and IL-10 are abnormal drop, detect TIMP-1, MMP-9, TNF-琢, IL-10 and TIMP-1 in maternal serum are beneficial to the diagnosis of premature rupture of membranes leading to premature delivery and it can clarify the maternal infection status. [ABSTRACT FROM AUTHOR]

Copyright of Chinese Journal of Tissue Engineering Research / Zhongguo Zuzhi Gongcheng Yanjiu is the property of Chinese Journal of Tissue Engineering Research and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Chinese Journal of Tissue Engineering Research / Zhongguo Zuzhi Gongcheng Yanjiu is the property of Chinese Journal of Tissue Engineering Research and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Hebei University of Science & Technology is the property of Hebei University of Science & Technology, Journal of Hebei University of Science & Technology and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)