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To observe the effect of breast cancer postoperative prescription on the quality of life, tumor markers and peripheral blood T lymphocyte subsets in patients with breast cancer after operation. From June 2017 to June 2018, 100 patients who were admitted to our hospital with long-term outpatient follow-up with breast cancer after operation were selected, and they were divided into control group (50 cases) and experimental group (50 cases) according to the double chromosphere method. The control group received routine standardized treatment of Western medicine, and the experimental group after operation received breast cancer postoperative prescription treatment on this basis. 1 year after treatment, the efficacy, quality of life, tumor markers, peripheral blood T cell subsets and 3-year disease-free survival rate were compared between the two groups. The total clinical effective rate in the experimental group was 84.00% (42/50), which was better than 56.00% (28/50) in the control group, there was significant difference between the groups (P<0.05). After treatment, the scores of symptom field were lower than those in the control group, and the scores of overall health status and functional field in the experimental group were higher than those in the control group (P<0.05). After treatment, the levels of serum carbohydrate antigen 125 (CA125), carcinoembryonic antigen (CEA) and tumor specific growth factor (TSGF) in the experimental group were lower than those in the control group (P<0.05). Compared with the control group, CD3+, CD4+, CD4+/CD8+in the experimental group after treatment increased, and CD8+ decreased (P<0.05). The 3-year disease-free survival rate in the experimental group was higher than that in the control group (P<0.05). The patients with breast cancer after operation use breast cancer postoperative prescription on the basis of conventional standardized treatment has a good effect, which can effectively control cancer, improve immune function, promote the improvement of life quality, and improve the 3-year disease-free survival rate. [ABSTRACT FROM AUTHOR]

Objective: To investigate the expression and clinical significance of of estrogen receptor (ER) and progesterone receptor (PR) in patients with acne breast carbuncle, and analyze their correlation with inflammatory factors. Methods: The expression of ER and PR in the breast lesions was detected by immunohistochemistry in 80 cases of acne breast carbuncle admitted to our hospital from January 2017 to December 2018, and serum levels of IL-1β, IL-6 and TNF-α were detected by enzyme-linked immunosorption (ELISA) to analyze the correlation between the expression of ER and PR in the breast lesions and serum levels of IL-1β, IL-6 and TNF-α levels. Results: Compared with mastitis group and mammary dilatation group, the serum levels of IL-1β, IL-6 and TNF-α in the granuloma group and abscess group were significantly increased, and compared with the granuloma group, the serum levels of IL-1β, IL-6 and TNF-α in abscess group were also significantly increased (P<0.05). There was no significant difference in the serum levels of IL-1β, IL-6 and TNF-α between mastitis group and mammary expansion group (P>0.05). The expression levels of ER and PR in the mastitis group, mammary dilatation group, granuloma group and abscess group were successively reduced (P<0.05). The expression of ER and PR were negatively correlated with serum levels of IL-1β, IL-6, but showed no significant correlation with the serum TNF-α level in the mastitis group and the mammary dilatation group (P>0.05). The ER and PR expression in granuloma group and abscess group were significantly negatively correlated with the serum levels of IL-1β, IL-6, TNF-α (P<0.05). Conclusion: Acne breast carbuncle has low or loss expression of ER and PR, which were significantly correlated with the inflammatory factors and severity of disease [ABSTRACT FROM AUTHOR]