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This experiment aims to design novel stationary phases for efficient separation of various analytes and apply them in teaching experiments. Covalent organic frameworks (COFs) were coated onto silica microspheres to synthesize core-shell structured composites (SiO2@COF), which were then employed as a mixed-mode stationary phase for high performance liquid chromatography (HPLC). Thanks to the excellent properties of the covalent organic framework, the alkylbenzenes, anilines, phenols, sulfonamides, nucleosides and polycyclic aromatic hydrocarbons (PAHs), were well separated on the SiO2@COF packed column. In addition, the SiO2@COFETTA-Td stationary phase was successfully applied in the separation of phthalates, antiepileptic drugs, and polycyclic aromatic hydrocarbons (PAHs) in PM2.5, further demonstrating its potential for the separation and analysis of complex biological samples. Through this experiment, students can master the operation of HPLC, deepen and consolidate their understanding of chromatography, grasp the principles of core-shell stationary phase separation, and improve their scientific thinking and innovation abilities. [ABSTRACT FROM AUTHOR]

Copyright of Gold (1001-1277) is the property of Gold Magazine Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of New Building Materials / Xinxing Jianzhu Cailiao is the property of New Building Materials Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Pancreatic schwannoma is an extremely rare neurogenic tumor, lacking of specific clinical manifestations and imaging signs. It is difficult to make a definite diagnosis before operation, and it is frequently misdiagnosed with other benign and malignant tumors of the pancreas. In this article, the diagnosis and treatment of a patient with pancreatic schwannoma were reported. The 44-year-old female patient was admitted to the hospital because of pancreatic mass found by physical examination for 5 days. Abdominal enhanced CT scan showed pancreatic body mass, approximately 6.4 cm×5.4 cm in size. The patient underwent middle pancreatectomy and distal pancreatic stump jejunum Roux-en-Y anastomosis. Postoperative pathological report was consistent with pancreatic epithelioid schwannoma. During the follow-up of 2 years, no tumor recurrence or metastasis was found. This case provides clinical reference for clinicians to diagnose and treat pancreatic schwannoma. [ABSTRACT FROM AUTHOR]

Copyright of Acta Materiae Compositae Sinica is the property of Acta Materiea Compositae Sinica Editorial Department and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

To construct a prognostic model of hepatocellular carcinoma（HCC）based on bioinformatics analysis of genes related to lipid metabolism，and to analyze its correlation with clinicopathological features. Methods The mRNA transcriptome data and clinical data of HCC tissues and normal liver tissues were downloaded from the Cancer Genome Atlas（TCGA）Database and the International Cancer Genome Consortium（ICGC）Database（the main ethnic groups in TCGA database are Europeans and Americans，and we only download the ICGC data from Asian ethnic groups）. Gene sets-related to lipid metabolism were downloaded from gene set enrichment analysis（GSEA），and gene enrichment analysis was performed on the gene sets by GSEA software（version 4. 0. 1）. The lipid metabolism-related genes differentially expressed in HCC were screened by Perl and R software from gene sets. Cox regression analysis was used to screen out the lipid metabolism genes related to the prognosis of HCC，and the prognosis prediction model was constructed. Risk scores of the models for HCC patients in TCGA and ICGC databases were calculated. Then HCC patients were divided into the high risk group and low risk group according to the median score. Kaplan-meier survival analysis was performed for the two groups，and receiver operating curve（ROC）was plotted. According to the clinical data of patients in TCGA database， nomogram was drawn to evaluate the predictive ability of the model for HCC patients prognosis. Cox regression was used to analyze the impact of the risk score and the clinical parameters on the prognosis of patients with HCC. Results There were 757 lipid metabolism-related genes in the gene sets，among which，109 up-regulated genes were screened for univari⁃ ate Cox analysis. The results showed that 21 lipid metabolism genes were associated with prognosis. Multivariate Cox analysis screened out 6 lipid metabolism genes that could independently affect the prognosis of HCC，including DAGLA，PC⁃ SK9，PIGU，FABP6，GLA，and ESYT3. Six lipid metabolism genes were used to construct a prognostic model for HCC. Risk score =DAGLA×0. 161 878 597+PCSK9×0. 014 967 28+PIGU×0. 043 461 843+FABP6×0. 078 505 362+GLA× 0. 019 799 065+ESYT3×0. 27 806 377. Kaplan-Meier survival analysis results in TCGA and ICGC databases showed that the survival time of HCC patients in the high-risk group was lower than that in the low-risk group（P<0. 01）. The area under ROC curves of the two databases was 0. 732 and 0. 662. The C-index of the nomogram was 0. 706. Multivariate Cox regression analysis showed that the risk score of the model and TNM stage of HCC patients could be used as independent prognostic factors（P<0. 001）. Conclusion The prognosis prediction model of HCC based on lipid metabolism-related genes is successfully constructed，and the prediction ability of the model for the prognosis of HCC patients is good. [ABSTRACT FROM AUTHOR]

Copyright of Journal of Tea Science is the property of Journal of Tea Science Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Acta Materiae Compositae Sinica is the property of Acta Materiea Compositae Sinica Editorial Department and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Acta Materiae Compositae Sinica is the property of Acta Materiea Compositae Sinica Editorial Department and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Computer Engineering & Applications is the property of Beijing Journal of Computer Engineering & Applications Journal Co Ltd. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

The mixed ground is inevitable during the construction of tunnel by TBM. and it has a great influence. The linear culling tests were conducted by the mechanical rock fragmentation platform of Beijing University of Technology. The rock sample of the mixed ground were composed of sandstone and mudstone. In order to verify the rock fragmentation mechanism and efficiency under different penetration, the rock breaking phenomenon, ihe cutting force, ihe specific energy and the rock debris composition were analyzed during the tesis. The main conclusions could be summarized as follows; there were huge differences of cutting forces between the two kinds of rock, and the differences increased rapidly with the increase of penetration. The debris of the sandstone mainly consisted of coarse breccia and small gravel, while the debris of mudstone were primarily composed of breccia. Therefore, the rock fragmentation of the rock mixed ground could be simplified as a combination of rock breaking of different kinds of rock, which offered some guidance for design and construction of TBM. [ABSTRACT FROM AUTHOR]

Copyright of Shandong Medical Journal is the property of Shandong Medical Health Newspapers and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Transactions of the Chinese Society of Agricultural Engineering is the property of Chinese Society of Agricultural Engineering and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Southwest China Journal of Agricultural Sciences is the property of Editorial Department of Southwest China Journal of Agricultural Sciences and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Nankai Journal: Philosophy, Literature & Social Science Edition / Nankai Xuebao: Zhexue Shehui Kezue Ban is the property of Nankai Xuebao Bianjibu and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)