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S-nitrosylation modification is a selective and reversible post-translational modification of protein by high concentration of nitric oxide （NO）, which is related to a variety of cellular processes and tissue homeostasis. Most digestive system tumors interact with the development of inflammation. The body induces a great deal of NO in an inflammatory state and NO can modify the substrate protein S-nitrosylation. At present, it has been found that the expression of S-nitrosylation of proteins in a variety of cancer tissues is abnormal. Relevant studies at home and abroad show that the relationship between S-nitrosylation and tumor occurrence and development has become a current research focus. By briefly describing the mechanism of protein S-nitrosylation imbalance in the occurrence and development of different digestive system tumors and treatments,this review concludes that S-nitrosylation imbalance in different digestive system tumors can promote or inhibit the development of tumors through the S-nitrosylation of different proteins and aims to tap the therapeutic potential of S-nitrosylation level in digestive system tumors [ABSTRACT FROM AUTHOR]

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Copyright of Rare Metal Materials & Engineering is the property of Northwest Institute for Nonferrous Metal Research and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)