Back to Search
Start Over
蛋白质 S-亚硝基化与消化系统肿瘤关系的研究进展.
- Source :
-
Journal of Kunming Medical University / Kunming Yike Daxue Xuebao . 2022, Vol. 43 Issue 9, p155-159. 5p. - Publication Year :
- 2022
-
Abstract
- S-nitrosylation modification is a selective and reversible post-translational modification of protein by high concentration of nitric oxide (NO), which is related to a variety of cellular processes and tissue homeostasis. Most digestive system tumors interact with the development of inflammation. The body induces a great deal of NO in an inflammatory state and NO can modify the substrate protein S-nitrosylation. At present, it has been found that the expression of S-nitrosylation of proteins in a variety of cancer tissues is abnormal. Relevant studies at home and abroad show that the relationship between S-nitrosylation and tumor occurrence and development has become a current research focus. By briefly describing the mechanism of protein S-nitrosylation imbalance in the occurrence and development of different digestive system tumors and treatments,this review concludes that S-nitrosylation imbalance in different digestive system tumors can promote or inhibit the development of tumors through the S-nitrosylation of different proteins and aims to tap the therapeutic potential of S-nitrosylation level in digestive system tumors [ABSTRACT FROM AUTHOR]
Details
- Language :
- Chinese
- ISSN :
- 2095610X
- Volume :
- 43
- Issue :
- 9
- Database :
- Academic Search Index
- Journal :
- Journal of Kunming Medical University / Kunming Yike Daxue Xuebao
- Publication Type :
- Academic Journal
- Accession number :
- 160220864
- Full Text :
- https://doi.org/10.12259/j.issn.2095-610X.S20220911