Search

Target detection in adverse conditions such as low illumination has always been a challenging. The factors of low light and fog can lead to reduced visibility and increased noise in images, significantly disrupting the precision of object detection. To address these issues, this paper proposed and integrated a low-light image enhancement network for machine vision perception, MVP-Net, with the YOLOv3 object detection network to construct an end-to-end enhancement detection framework, MVPYOLO. MVP-Net employed inverse mapping network technology to transform conventional RGB images into pseudo-RAW image feature space and introduced a pseudo-ISP enhancement network, DOISP, for image enhancement. The objective of MVP-Net is to harness the potential advantages of RAW images in object detection while overcoming the limitations encountered in their direct application. The model has outperformed previous works on multiple real-world low-light datasets and is adaptable to detectors with various architectures. Its end-to-end detection framework achieves a mAP(50%) metric of 78.3%, an improvement of 1.85% over the YOLO detectors. [ABSTRACT FROM AUTHOR]

The weakly supervised methods for image semantic segmentation using the image-level labels are a relatively popular research direction. The class activation maps generation approach is the most commonly used approach in these researches. Due to the sparsity of class activation maps, the accuracy of discriminative regions is generally low. To address these problems, this paper proposed an improved weakly supervised image learning method based on the Transformer network. Firstly, it introduced a spatial attention interaction layer to extend the coverage of the class activation maps. Secondly, it designed an attention adaptive module to guide the model to enhance the class response in weak regions. In particular, it constructed an adpative cross domain to improve the model classification performance during class generation. The method achieves the accuracies of 73.5% and 73.0% on the Pascal VOC 2012 validation sets and test sets, respectively. The experimental results prove that the refined Transformer network learning method can improve the image semantic segmentation performance of weakly supervised method. [ABSTRACT FROM AUTHOR]

There are many fields choose to fuse LiDAR point cloud and camera images for applying. The accurate extrinsic calibration is a prerequisite for fusing their information. The point cloud feature extraction is a key step in extrinsic calibration. However, the low resolution and low quality of point clouds can affect the accuracy of calibration results. To address these problems, this paper proposed a LiDAR and camera extrinsic calibration method based on edge correlation point cloud. Firstly, it extracted the edge correlation point cloud of the calibration plate by using dual echoes. Then, it obtained the corner points from the edge correlation point cloud by the optimization method, where the corner points were compatible with the actual calibrated plate size. Finally, it matched the corner points in the point cloud with corner points in the image, and solved the extrinsic parameter between the LiDAR and the camera by the multi-point perspective method. The experimental results show that the reprojection error of the method is 1. 602 px, which is lower than that of comparison methods, verifying the effectiveness and accuracy of the method. [ABSTRACT FROM AUTHOR]

A class of multi-objective fractional semi-infinite optimization problems with uncertain data were investigated. Firstly, a robust optimization model corresponding to the uncertain multi-objective optimization problem was introduced. Then the optimization model was converted to a multi-objective optimization problem with the Dinkelbach method. In turn, by means of the scalarization method, the corresponding scalarization optimization problem was built, and the relationship between robust solutions to the multi-objective optimization problem and its corresponding scalarization optimization problem was described. Finally, through a robust-type sub-differential constraint qualification, the robust optimality condition for approximate quasi-efficient solutions to the multi-objective fractional optimization problem was established. [ABSTRACT FROM AUTHOR]

Objective: To investigate the effects of kaempferol on the changes of intestinal mucosal barrier and immune function in rats with severe acute pancreatitis. Methods: The rat model of severe acute pancreatitis was established, and the rats were randomly divided into 6 groups: sham operation group, model group, kaempferol low-dose group, kaempferol medium-dose group, kaempferol high-dose group and dexamethasone group. Pathological damage of pancreatic tissue was detected by HE staining and pathological scores were obtained. Serum diamine oxidase （DAO）, serum D-lactic acid, IL-6, TNF-α and IL-1β levels were detected by ELISA. Serum amylase and lipase were detected by automatic biochemical analyzer. Mucosal thickness and villus height were measured by automatic image analyzer. NLRP3, ASC, Cleaved caspase-1/caspase-1, p-Nrf2, Nrf2, NQO1 and HO-1 expressions were detected by Western blot. Results: Compared with sham operation group, the serum levels of DAO, D-lactic acid, amylase and lipase in model group were increased （P<0.05）, the mucosal thickness and villus height were decreased （P<0.05）, and the levels of IL-6, TNF-α and IL-1β were increased （P<0.05）. NLRP3, ASC and Cleaved caspase-1/Caspase-1 expressions were increased （P<0.05）; Compared with model group, the histopathological damage of pancreas in kaempferol medium and high dose groups and dexamethasone groups were significantly improved, the histopathological score of pancreas was decreased （P<0.05）, the levels of serum DAO, D-lactic acid, amylase and lipase were decreased （P<0.05）, and the mucosal thickness and villus height were increased （P<0.05）. The levels of IL-6, TNF-α and IL-1β were decreased（ P<0.05）, and the expressions of NLRP3, ASC and Cleaved caspase-1/Caspase-1 were decreased （P<0.05）, the p-Nrf2/Nrf2 and the protein expression of NQO1 and HO-1 were increased （P<0.05）. Conclusion: Kaempferol can effectively improve the immune function of severe acute pancreatitis model rats, improve the protective function of intestinal mucosal barrier, inhibit the release of inflammatory factors, inhibit the activation of NLRP3/ASC/Caspase-1 pathway, and activate the Nrf2/NQO1/HO-1 pathway. [ABSTRACT FROM AUTHOR]

Objective To investigate the relationships between blood lipids and the risk of recurrence after radical prostatectomy (RP). Methods Totally 161 prostate cancer patients undergoing RP were enrolled, including 68 cases of medium-low prognosis risk and 93 cases of high prognosis risk. After a follow-up period of 3 years, biochemical recurrence was observed in 45 patients while no biochemical recurrence occurred in 116 patients. The general data, laboratory examination results, Gleason score and clinical stage of the subjects were collected. A comparison of the collected data was made between the medium-low risk group and the high-risk group, as well as between the biochemical recurrence group and the non-recurrence group. Indexes with statistically significant differences were included in the multivariate Logistic regression model to identify the risk factors associated with high prognosis risk and biochemical recurrence. Results Compared with the medium-low risk group, the high-risk group exhibited a higher abnormal rate of HDL-C and an elevated level of Lp (a)（both P<0. 05). Multivariate Logistic regression analysis revealed that abnormal HDL-C level was a high risk factor for prognosis of patients after RP (P<0. 05). The abnormal rates of HDL-C and Lp (a), the levels of Lp (a) and PSA, the proportions of Gleason score ≥8 and clinical stage ≥T2c were higher in the recurrence group than in the non-recurrence group (all P<0. 05). Multivariate Logistic regression analysis showed that high-grade clinical stage (≥T2c), elevated PSA level and abnormal Lp (a) level were risk factors for recurrence in patients undergoing RP (all P< 0. 05). Conclusions The abnormal serum HDL-C and Lp (a) are associated with the high prognosis risk and biochemi⁃ cal recurrence in patients undergoing RP. [ABSTRACT FROM AUTHOR]

Objective To understand the health nutritional status among residents in Jiangxi Province and to explore the related factors influencing the residents health literacy to provide a scientific basis for the government departments to formulate the health promotion related policy. Methods A total 3 289 permanent residents aged 15-69 years old were extracted from 33 villages and towns (streets) in 11 counties (districts) of Jiangxi Pprovince from June to December 2012 by using the multi-stage stratified cluster random sampling method. Results The overall level of residents health literacy in Jiangxi Province was 7.58%; the proportions of basic health knowledge and idea, healthy lifestyle and behaviors, and health basic skills were 13.47%, 11.56% and 8.04% respectively; the proportions of scientific health concept, safety and emergency literacy,prevention and treatment literacy of infectious diseases,health information literacy, prevention and treatment literacy of chronic disease and basic medical literacy were 31.47%, 29.28%,12.22%, 11.00%, 9.69% and 4.79% respectively. The Logistic regression analysis showed that the culture degree, occupation and average month income were the independent influencing factors of residents health literacy (P<0.05). The proportion of health literacy in civil servants and medical staffs was significantly higher than that in other occupation groups (OR=3.954, 3.822, P=0.016, P=0.010). Conclusion Conducting the resident health education intervention work should be strengthened according to the characteristics of different populations. The populations of low cultural level and low income should be focused for pertinently increasing the health literacy level in population of the whole province. [ABSTRACT FROM AUTHOR]

The experiment was to investigate the effect of Artemisia scoparia Waldst. et Kit. powder on growth performance, antioxidant capacity and immunity of Litopenaeus vannamei. A total of 2 100 healthy white shrimp with an body length about 2.5 cm were randomly divided into seven groups, with three replicates in each group and 100 shrimp in each replicate. The shrimp in blank control group (group A) were fed with basal diet, the shrimp in positive control group (group B) were fed with basic diet and 5 ml/L Pentanthus extract was thrown into the water, and shrimp in experimental groups were fed with basal diet supplemented with 0.5%, 1.0%, 2.0%, 4.0% and 8.0% Artemisia scoparia Waldst. et Kit. powder, respectively. The experiment lasted for 42 d. The results showed that compared with group A, SR, WGR, CF, HIS, SGR were significantly increased in all groups (P<0.05), FCR significantly decreased (P<0.05). Compared with group B, WGR and SGR in Artemisia scoparia Waldst. et Kit. powder supplemental groups were significantly increased (P<0.05). Compared with group A, the content of ammonia nitrogen in all groups except 0.5% group was significantly decreased (P<0.05), except for group B, the nitrite content and pH value of whole shrimp culture water in each group were significantly decreased (P<0.05), pH value of aquaculture water in each group was significantly decreased (P<0.05). Compared with group A, MDA content in hepatopancreas in Artemisia scoparia Waldst. et Kit. powder supplemental groups was significantly decreased (P<0.05), and activitiy of SOD, CAT and PPO were significantly increased (P<0.05). Compared with group A, the mRNA expression levels of Toll-1 and Toll-2 in hepatopancreas tissues in Artemisia scoparia Waldst. et Kit. powder group were significantly decreased (P<0.05). The experiment indicates that Artemisia scoparia Waldst. et Kit. powder can promote growth, antioxidant capacity and non-specific immunity of Litopenaeus vannamei, and the appropriate supplemental ratio is 1.0%~2.0%. [ABSTRACT FROM AUTHOR]

The effects of laser cladding power， scanning speed and cladding materials on the microstructure and wear resistance of the cladded coating on 45# steel were investigated. The results show that the gradient cladded layer is continuous without the defects of crack pores and is metallurgically bonded to the 45# steel matrix.The microstructure of the cladded layer are characterized by dendritic crystals， equiaxed crystals and other rapid solidification structures， which is composed of α-Fe， CrNiFe-C and Cr7C3. The microhardness of the cladded layer is gradient， and the surface hardness of the cladded layer and the transition layer are 7.48GPa and 5.52GPa， respectively， which is 3.74 and 2.76 times of the hardness of the substrate.Therefore， the laser cladding technology can significantly improve the wear resistance of 45# steel. [ABSTRACT FROM AUTHOR]

Objective: To investigate the influencing factors of the effect of dydrogesterone in the treatment of early threatened abortion, and follow up the pregnancy outcome of patients with continued pregnancy. Methods: 300 patients with early threatened abortion who were admitted to our hospital from January 2017 to January 2019 were selected. All patients were given the first dose of dydrogesterone 40 mg/time orally, then changed to 30 mg/time, twice a day. They were divided into effective group and ineffective group according to whether the treatment was effective or not, basic clinical dataes of the two groups were collected. Multivariate Logistic regression was used to analyze the influencing factors of the effect of dydrogesterone on early threatened abortion, and the pregnancy outcome was followed up. Results: Among the 300 patients, 245 cases (81.67%) were effective, and 55 cases (18.33%) were ineffective. Univariate analysis showed that compared with the ineffective group, the age, gestational times, abortion times, birth times and anti-endometrial antibody(EMAb) positive rate in the effective group were lower, and the serum levels of β-human chorionic gonadotropin (β-HCG), progesterone (P) and estradiol (E2) were higher, and the differences were statistically significant (P＜0.05). Multivariate Logistic regression analysis showed that: Age (older), gestational times (more), birth times (more), abortion times (more) and EMAb positive were the risk factors affecting the effect of dydrogesterone treatment (P＜0.05). Serum β-HCG (higher), P (higher) and E2 (higher) were the protective factors affecting the effect of dydrogesterone treatment (P＜0.05). Follow-up results showed that the average gestational age of the 245 patients with continued pregnancy was (39.43± 1.06) weeks. The maternal outcomes were as follows: 6 cases had postpartum hemorrhage, and 17 cases had postpartum placental adhesion. Neonatal outcome: Apgar score was (9.43 ± 0.20) score, preterm delivery occurred in 2 cases, malformation occurred in 1 case, and right umbilical vein was permanent in 1 case. Conclusions: Age, pregnancies times, abortion times, EMAB positive, serum β-HCG, P and E2 are the influencing factors for the efficacy of dydrogesterone in the treatment of early threatened abortion, whether the treatment of Early Threatened Abortion with didroxyprogesterone can increase the risk of adverse maternal and neonatal outcomes remains to be further studied. [ABSTRACT FROM AUTHOR]

OBJECTIVE: To investigate the status of medication errors (ME) in women and children in Beijing Obstetrics and Gynecology Hospital, Capital Medical University (hereinafter referred to as "our hospital"), and to discuss the prevention strategies, so as to provide reference for improving medication safety in this field. METHODS:ME reports of our hospital reported on Chinese clinical drug safety monitoring network from 2016 to 2019 were collected and analyzed. Items included the triggering links, classification, involved drugs, error content, triggering factors and injury incidents. RESULTS: A total of 394 cases of ME were collected. ME reports of B, C, D, and E accounted for92. 39% (364 cases), 3. 81% (15 cases), 1. 78% (7 cases) and 2. 03% (8 cases), respectively. There were no ME reports of A and F to I. Internal errors that did not reach the patient accounted for 90. 10% (355 cases). Totally75. 00% (6 cases) of ME reports of E were induced by the patients’ medication error. And 23. 60% (93 cases) of ME were special population (including pregnant women, lactating women and infants). The top three drugs ranked by the number of ME reports were respectively Misoprostol tablets, Progesterone soft capsules and Dydrogesterone tablets. In terms of classifications of ME contents, the most errors in clinicians ’ prescriptions (medical order) were mainly dosage, route of administration and frequency of administration. The error of variety was the most in drug dispensing by pharmacists. Medication errors focused on dosage and administration techniques. The main factors of ME were imperfect information system, lack of knowledge and similar drug names. Drugs with similar appearance and sound mainly involved three categories of Chinese patent medicine for gynecology, estrogen and progesterone and topical drugs for gynecology. CONCLUSIONS: Attention should be paid to the prevention of ME in women and children, and relevant strategies should be developed to reduce the occurrence of ME. [ABSTRACT FROM AUTHOR]

Objective To study the conservative treatment for cesarean scar pregnancy (CSP) with proper medications. Methods One case of CSP with uterine apoplexy was reported. Medication regimens were illustrated as the conservative treatments for the patient with β-HCG>20 000 IU/L, in whom surgery was contraindicated. Results After two times of uterine artery embolization and chemotherapy (MTX50 mg), followed by three times of MTX50 mg cervical injection combined with oral mifepristone, serum β-HCG dropped to normal level and no adverse reactions were observed. Conclusion Clinical pharmacists could strengthen the safety and effectiveness of rational drug use by participating in the integrated pharmacy care. [ABSTRACT FROM AUTHOR]