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Objective To investigate the effect of early activity combined with electrical stimulation of neuromuscular system in improving intensive care unit (ICU)-acquired weakness (ICU-AW) patients with severe pneumonia. Methods A total of 150 patients with ICU-AW caused by severe pneumonia admitted to emergency intensive care unit(EICU) in a tertiary hospital in Shanghai were enrolled as the study subjects, and randomly divided into control group (75 cases) and combined group (75 cases). The control group took early exercise, and the combination group was given early exercise plus electrical stimulation of neuromuscular system. The recovery from mechanical ventilation (ICU length of stay, duration of mechanical ventilation, weaning extubation rate, ICU rollout rate), lung function [forced vital capacity (FVC), forced expiratory volume in the 1 s (FEV1)/FVC, massive inspiratory pressure (MIP)],muscle strength[Medical Research Council (MRC) score], disease severity[acute physiology and chronic health evaluation II (APACHE II)], and complications were compared between the two groups. Results The ICU length of stay and mechanical ventilation time in the combined group were significantly lower than those in the control group (P＜0.05). After intervention, FVC, FEV1/FVC, MIP and MRC scores in the two groups were significantly increased(P＜0.05), and compared with the control group, the combined group was significantly increased(P＜0.05). After intervention, APACHE II score was significantly reduced in the two groups(P＜0.05), and compared with the control group, APACHE II score in combined group were significantly reduced (P＜0.05). The complication rate in the combined group (9.33%) was significantly lower than that of control group (24.00%) (P＜0.05). Conclusions Early exercise combined with neuromuscular electrical stimulation in patients with severe pneumonia ICU-AW can effectively promote recovery of patients because of improved lung function. This therapy is proved to be be safe and effective. [ABSTRACT FROM AUTHOR]

To observe the effect of Xiaozheng zhitong decoction combined with auricular point pressing beans on inflammatory factors and prostaglandin E2 (PGE2) and prostaglandin F2α (PGF2α) in patients with endometriosis(EMT) dysmenorrhea of qi stagnation and blood stasis type. 98 EMT dysmenorrhea patients who were admitted to Zhongshan Hospital of Traditional Chinese Medicine Affiliated to Guangzhou University of Chinese Medicine from March 2021 to December 2022 were selected as research objects. Patients were divided into control group（conventional western medicine treatment, n=49）and study group （xiaozheng zhitong decoction combined with auricular point pressing beans on the basis of control group, n=49）by random number table method. The efficacy, pain score [pain visual analogue scale (VAS), COX dysmenorrhea symptom score], chinese medicine syndrome scores, inflammatory factors [interleukin-6 (IL-6), tumor necrosis factor-α (TNF-α), interleukin-8 (IL-8)] and PGE2 and PGF2α levels were compared between two groups. The total clinical effective rate in study group was higher than that in control group(P<0.05). 3 courses after treatment, the VAS, COX dysmenorrhea symptom score and total chinese medicine syndrome scores in study group were lower than those in control group (P<0.05). 3 courses after treatment, the levels of IL-6, TNF-α and IL-8 in study group were lower than those in control group (P<0.05). 3 courses after treatment, PGE2 in study group was higher than that in control group, and PGF2α was lower than that in control group (P<0.05). Xiaozheng zhitong decoction combine with auricular point pressing beans in the treatment of EMT dysmenorrhea patients with qi stagnation and blood stasis type can effectively improve dysmenorrhea symptoms, reduce TCM syndrome scores, and regulate serum inflammatory factors and PGE2 and PGF2α levels. [ABSTRACT FROM AUTHOR]

To provide theoretical basis and technical support for the planting and cultivation of Camelina sativa under stress and clarify the effects of branched chain amino acids(BCAAs) on Camelina sativa seed germination under drought and salt stress. In this study, SC-N16, a cultivate of Camelina sativa, was used as material. The drought stress and salt stress models were established using polyethylene glycol 6000(PEG) and sodium chloride(NaCl). And then leucine(Leu), isoleucine(Ile), and valine (Val) solution were selected to soak the seed of Camelina sativa. Statistical analysis of the effects of BCAAs to the germination indexes of Camelina sativa, including germination rate, germination potential, germination index, root length, bud length, fresh weight, and dry weight was conducted. The results showed that when the model of drought stress and salt stress was 0.20 g/mL of PEG and 150 mmol/L of NaCl respectively. The seed germination ability of Camelina sativa was improved through the treatment of three BCAAs. Among them, the best alleviation effect of BCAAs on seeds germination was observed with the treatment of 100 μmol/L Valine. Compared with the model of drought stress, its germination potential and germination rate increased by 164.78% and 34.76%, respectively. Compared with the model of salt stress, those two indexes increased by 36.98% and 29.77%, respectively. When the concentration range of Val was further expanded in from 0 to 250 μmol/L, the alleviation effect of Val on Camelina sativa seed germination under drought and salt stress showed a trend of first increase and then decrease as the increase of Val concentration. In particularly, the optimal concentration of Val was remained at 100 μmol/L. Compared with drought stress by PEG, the root length, bud length, dry weight, and fresh weight increased by 19.61%, 30.77%, 28.66% and 9.53%, respectively. Compared with salt stress by NaCl, the indexes increased by 21.05%, 38.63%, 27.14% and 7.83%, respectively. In conclusion,under the stress of drought and salt, when the exogenous BCAAs was Val and its concentration was 100 μmol/L, the alleviating effect on seed germination of Camelina sativa was optimal. [ABSTRACT FROM AUTHOR]

To address the issue of unreasonable fertilization in the nectarine orchards of Shanxi province and to determine the appropriate proportion and quantity of fertilizer for nectarine production, four-year-old “Jinrui” nectarines were served as the experimental subject. With a fixed phosphate fertilizer application rate, four nitrogen gradients and four potassium gradients were established, in addition to a control group that received no fertilization to study the impact of different fertilization regimens on the yield and quality of the “Jinrui” nectarines in Yuncheng. The results indicated that the proper increasing application of N and K fertilizers could significantly improve transverse and longitudinal diameters, as well as the weight of individual fruits. The treatments increased the contents of soluble solids, total soluble sugars, and vitamin C, while reduced total acidity and enhanced the sugar-to-acid ratio in nectarine fruits, effectively boosted fruit quality and taste. Nevertheless, when the nitrogen application rate exceeded 240 kg/ha, there was a decrease in soluble solids, vitamin C, and soluble sugar content, which in turn adversely affected nectarine quality and yield. In comparison to the absence of fertilization, the treatment N2PK2(N 240 kg/ha, P2O5 120 kg/ha, and K2O 240 kg/ha) and the treatment N2PK3(N 240 kg/ha, P2O5 120 kg/ha, K2O 360 kg/ha) enhanced the yield by 28.77% and 31.34% respectively, resulting in increased output values of 25 440 RMB/ha and 27 720 RMB/ha correspondingly. These two fertilization treatments yielded economic benefits substantially higher than all other treatments. By creating a fertilizer application model, the optimal potassium rate for “Jinrui” nectarines was identified as 398 kg/ha. In summary, the fertilization ratio and the amount markedly influenced the internal quality and yield of the nectarines. The ideal nitrogen, phosphorus, and potassium fertilization ratio for nectarines at the test site was 1∶0.5∶1 to 1∶0.5∶1.5, with recommended fertilizer quantities being 240 kg/ha of nitrogen, 120 kg/ha of phosphorus, and 240-360 kg/ha of potassium. [ABSTRACT FROM AUTHOR]

In this experiment, bacterial residue based biochar was used as the main raw material, and phosphate rock and chitosan were compounded by ultrasonic oscillation. The optimum ratio of the composite materials was screened by batch water adsorption test. On this basis, the effects of bacterial residue based biochar and the composite materials on Cd2+ adsorption were investigated from the aspects of material addition amount, solution pH, adsorption time, and initial mass concentration of Cd solution. The results showed that the optimum ratio of bacterial residue based biochar, phosphate rock, and chitosan was 7∶1∶2, at different Cd solution mass concentrations, the adsorption rate of Cd by the composite materials was higher than that by bacterial residue based biochar. With the increase of the initial mass concentration of Cd solution, the difference in adsorption rate between the two measures gradually increased. When the pH value of Cd solution was 7 and the addition amount in 100 mg/L of Cd solution was 0.6 g, the disfference in the adsorption rate of Cd by the composite material and bacterial residue based biochar was the largest. The adsorption rate of the composite material was about 65% after 5 times of desorption. The addition of exogenous ions inhibited the removal rate of Cd2+ by bacterial residue based biochar and the composite materials, but the inhibitory effect on the composite materials was weaker than that on bacterial residue based biochar. When the mass concentration of Cd2+ was 100 mg/L, the addition amount of bacterial residue based biochar and the composite materials was 0.6 g, the adsorption capacity of bacterial residue based biochar and the composite materials reached 3.859 mg/g and 6.310 mg/g respectively after 240 min of oscillation. The adsorption process of Cd2+ by the composite material was highly fitted with the pseudo-second-order kinetics and Langmuir model, and was dominated by chemical adsorption on the single-layer surface. Heating up could effectively improve the adsorption capacity of Cd2+ by the composites and bacterial residue based biochar. [ABSTRACT FROM AUTHOR]

目的探讨糖尿病视网膜病变(DR)患者血清神经元特异性烯醇化酶(NSE)水平变化及意义。方法选取糖尿病患者137例,根据有无DR分为DR患者110例、无DR患者27例。采集清晨空腹静脉血,检测血清NSE水平。比较有无DR患者的临床病理特征,Logistic回归法分析血清NSE水平与DR的关系。建立血清NSE水平的受试者特征曲线(ROC),评价NSE对DR的诊断效能。结果合并DR的糖尿病患者血清NSE水平高于无DR患者(P均<0.05)。血清NSE水平与DR密切相关(OR=1.248,95%CI为1.070~1.457,P=0.005)。血清NSE水平预测DR的ROC为0.658(95%CI为0.572~0.737,P<0.01),灵敏度为69.09%,特异度为59.26%。结论合并DR的糖尿病患者血清NSE水平高于无DR患者,NSE是DR发生的独立危险因素,对DR的诊断具有一定临床应用价值。 [ABSTRACT FROM AUTHOR]

The saline land are 920.9 million hectares in China, and about 69.03% of it is distributed in the 6 western provinces belonging to the inland arid and cold area. Drought and wind in the early spring, and low soil temperature coupled with the harm of saline alkali often result in the low rate of maize emergence and weak growth of the seedlings. The study aimed to investigate the desalination effect of all-film double-furrow sowing in saline land in the arid and cold area. In 2012, 3 cultivation patterns were compared including all-film double-furrow sowing (QM), half-film mulch ridge sowing (LB) and half-film mulch hole sowing (CK). The spatio-temporal dynamics of temperature, soil moisture and salinity in the plowed soil during the growth of maize were analyzed and their effects on the rate of emergence, the process of growth and the yield of maize were assessed in Datong, Shanxi Province. The results showed that the soil temperature of QM and LB was increased significantly than CK in early growth stage. The warming effect of LB was highest in the seedling period and that of QM was in the jointing period. The water-salt environment in soil was optimized greatly in the QM treatment, and the emergence rate and the seedling rate of maize increased greatly. The soil moisture in the QM treatment at 0-30 cm was 3.6% and 2.9% higher than that in the LB and CK treatments under the drought conditions during the seedling stage, respectively, and 27.8% and 7.0% higher in the middle stage, respectively. The soil moisture of LB, QM and CK treatment in 1-m soil depth was 21.7%, 13.9% and 13.6%, respectively. The soil moisture of plow layer in the QM treatment was higher than that of CK, indicating that the QM treatment was good at water supply to plant. The soil salinity in the QM treatment reduced, which was 28.3% and 36.3% lower in the middle stage and 31.2% and 30.5% lower in the late stage than that of LB and CK, respectively. In the harvest season, the soil salinity of LB and CK was maximized in 30 cm depth but that of the QM was not accumulated in 30 cm. The emergence rate of the LB was highest, and the seedling rate of the QM was highest. In the big trumpet period, the plant height of QM was 20.3% and 27.1% higher and the dry weight was 49.6% and 57.3% than that of LB and CK, respectively. The maize in the QM treatment matured 4 days earlier than that in the CK and LB. The grain yield in the QM treatment increased by 69.7% and 125.3% compared to CK and LB, respectively. In short, the use of QM treatment could optimize the water-salt distribution in plowed soil, improve germination rate, shorten the growth period of maize, and considerably increase grain yield. All-film double-furrow sowing is a good cultivation pattern for saline land in inland cold arid area. [ABSTRACT FROM AUTHOR]

The objective of this study was to explore the spatial-temporal variability of soil organic matter(SOM)and its influencing fac tors. Based on the data of 168 sample points collected in 1982 from the Second Soil Survey and 213 soil sample points collected in 2017 of the Xiaohe River basin in the eastern Loess Plateau, the spatial and temporal variation of soil organic matter in the drainage basin in the last 35 years and the influencing factors were analyzed by statistical and geostatistics methods. The results showed that from 1982 to 2017, the mean value of soil organic matter in cultivated soil increased from 11.06 g·kg-1 to 15.69 g·kg-1, and the amplification reached 41.86%. In the recent 35 years, the organic matter in the farmland of the Xiaohe River basin had an increasing trend, and the spatial distribution in creased gradually from the central part to the surrounding area. From the year of the second soil census to 2017, the organic matter content of the soil in the ploughed layer showed the rule of gradually accumulated from lower level to higher level. Among them, the land area of soil organic matter content >20 g·kg-1 and 15~20 g·kg-1 increased from zero to 0.74% and 43.72% of the total area of the river basin re-spectively, the land area of 10~15 g·kg-1 decreased the most, and it reached 29.93%, 6~10 g·kg-1 decreased from 13.82% to 1.57%, and <6 g·kg-1 decreased from something to nothing. Soil parent material, topography change, planting structure and fertilization are the main factors that affect the temporal and spatial differentiation of soil organic matter. Human beings show an increasing trend of soil nutri ent intervention, and we should be paid attention to the regional management of soil fertilizer to ensure the sustainable development of the whole agricultural watershed. [ABSTRACT FROM AUTHOR]

[Objective] Microbes can effectively improve the conversion efficiency of weathered coal. Due to the differences of geographical condition and age, weathered coals usually showed different physical and chemical properties,which affected the degradation of microbes. Therefore, the definition of degradation characteristics of different weathered coals could effectively improve its conversion efficiency. [Method] In this study,taken Three different sources of weathered coal as tested materials, the strain ‘F75’ was screened and identified, which could degrade weathered coal. [Result]Under the solid and liquid culture, the degradation characteristics of the contents and structure of humic acids of the strains from weathered coals were analyzed. The strain ‘F75' could degrade the three sources of weathered coals and was identified as Aspergillus niger. Under the liquid culture, the UV analysis showed that the curves of F75 to the YF01 and YF09 increased firstly and then decreased from 190 nm to 280 nm, whereas the curve of F75 to the YF06 increased in this stage, and all the weathered coals showed obvious enhancement before 205 nm. The results of FT-IR showed that under the action of YF01 . the carbon chain of F75 was shortened, with higher rate of weight loss, and for the YF06 and YF09, the content of water-soluble humic acid and fulvic acid increased, which implied that the effect of F75 to YF06 and YP09 concentrated in the carboxyl groups. Under the solid culture condition, the content of free humic acid of YF06 significantly increased when F75 was added; The content of water soluble humic acid and fulvic acid of three weathered coals significantly increased with F75 addition, of which the increase of water soluble humic acid had a dominant effect on YF09 and some consumption effect on YF06. [Conclusion] During the degradation of different sources of weathered coals according to the rate of weight loss and the content of humic substances, the strain had different dominant effects, which would guide the further transformation of weathered coal. [ABSTRACT FROM AUTHOR]

Objective To investigate the effect of clomiphene citrate （CC） on endometrial estradiol receptor （ESR） expression of Sprague-Dawley female rats. Methods 42 female rats， 200-250g， as the experimental group were intragastric administrated with CC （1 mg/Kg） and the 30 rats in control group were treated with the same count of physiological saline. Both of the two groups were treated for 6 days. All the endometrial slices were stained with hematoxylin and eosin， and the endometrial thickness was measured based on histology every day after CC administration. Then ESR of both groups was detected by Western Blotting. Results The endometrial thickness was significantly declined for D5-D6 days after CC treatment （ ＜0.05） . The ESR expression level was also significantly declined in CC group when compared with control group （ ＜0.05） . Conclusion The endometrial thickness and ESR expression level were both significantly declined after CC treatment. [ABSTRACT FROM AUTHOR]