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Copyright of Chinese Mental Health Journal / Zhongguo Xinli Weisheng Zazhi is the property of Chinese Mental Health Journal and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Chinese Mental Health Journal / Zhongguo Xinli Weisheng Zazhi is the property of Chinese Mental Health Journal and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objective To investigate the application value of conventional MRI signal intensity ratio (SIR) in differential diagnosis of glioblastoma (GBM) and primary central nervous system lymphoma (PCNSL) and the correlation with Ki-67 expression. Methods Retrospective analysis of 72 cases of GBM and 32 cases of PCNSL MRI data, t test were used to analyze signal intensity ratio of tumors, four indexes were included: signal ratio of T1WI (rT1), signal intensity ratio of T2WI (rT2), enhanced signal ratio of T1WI (rT1CE) and signal ratio of T2WI/T1WI (T2/T1). The differential diagnostic performance was evaluated by receiver operating characteristic (ROC) curve. Spearman test was used to analyze the correlation between SIR and (Ki-67 label index, Ki-67 LI). Results The rT1 and rT1CE (rT1: 0.482±0.117, rT1CE: 1.319±0.243) of GBM were significantly lower than that of PCNSL (rT1: 0.557±0.478, rT1CE: 1.594±0.156), while rT2 and T2/T1 (rT2: 1.814±0.285, T2/T1: 3.995±1.189) were significantly higher than that of PCNSL (rT2: 1.435±0.135,T2/T1: 2.600±0.354), the comparison between the two groups was statistically significant (P＜0.001). ROC curve analysis showed that rT1, rT2, rT1CE and T2/T1 could be used to distinguish GBM from PCNSL. A single parameter of T2/T1 had the best diagnostic efficacy (AUC: 0.877), with a sensitivity of 93.8% and a specificity of 76.4%. rT1 +rT1CE +rT2 +T2/T1 combined parameters had the highest differential diagnostic efficiency (AUC: 0.966), with sensitivity of 87.5% and specificity of 91.7%. Correlation analysis showed that rT1 and rT1CE were positively correlated with Ki-67 LI, the correlation coefficients were 0.301 and 0.399, while rT2 and T2/T1 were negatively correlated with Ki-67 LI, and the correlation coefficients were-0.428 and-0.459 respectively. Conclusion Tumor SIR in MRI is important for discriminating GBM from PCNSL, and SIR as a quantitative parameter can provide an important complement to subjective judgment and preliminarily evaluation for the proliferation level of tumor cells. [ABSTRACT FROM AUTHOR]

Copyright of Acta Scientiarum Naturalium Universitatis Sunyatseni / Zhongshan Daxue Xuebao is the property of Sun-Yat-Sen University and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Agro-Environment Science is the property of Journal of Agro-Environment Science Editorial Board and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Detergent & Cosmetics is the property of Detergent & Cosmetics Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of China Pulp & Paper is the property of China Pulp & Paper Magazines Publisher and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of China Pulp & Paper is the property of China Pulp & Paper Magazines Publisher and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objective: To test the protection effect of PEA and to explore the possible mechanism. Methods: The male SD rats were divided into three groups: sham operation group, model group and treatment group.The models of middle cerebral artery occlusion were established with the suture method. The rats of treatment group were received PEA (10 mg/kg i.p.) 30 min and 4h after ischemia. 24 h after the reperfusion, neurological deficit was scored, and then removed their brains. TTC staining was applied to quantify infarction volume. Xanthine oxidase method was usedto test the activity of SOD and the malondialdehyde (MDA) content were measured by the method of thiobarbituric acid reaction (TBA). The protein of Bcl-2 and Bax were tested by Western Blot analysis. Results: In our study, neurological function score of treatment group was 1.33± 0.49. and model group's was 2.20± 0.41. And we also measured the infarct volume of model group(243.40± 14.19 mm3) and treatment group(l 14.00± 8.63 mm3). So cmpared with model group, the neurological deficit scores and infarction volume of treatment group were significantly decreased (P<0.05). The MDA content of treatment group was 3.85± 0.29 nmol/mg prof, and model group's was 4.85± 0.30nmol/mg prot. The SOD activity of treatment group was 13.95± 0.71 U/mg prof, and model group's was 12.44± 0.40 U/mg prot. So compared with model group, the activity of SOD of treatment group increased significantly and the content of MDA decreased (P<0.05). hi the treatment group, the ratio of Bcl-2 protein content to (3-action protein content was 0.53± 0.013 %, and the ratio of Bax protein content to (3-action protein content was 0.54± 0.012 %. In the model group, the ratio of Bcl-2 protein content to (3-action protein content was 0.40± 0.012 %.and the ratio of Bax protein content to (3-action protein content was 0.80± 0.012 %. Compared with model group, the content of bcl-2 in treatment group increased significantly and the content of Bax was decreased significantly (P<0.05). Conclusion: The cerebral ischemia reperfiision injury was significantly reduced by PEA administration. PEA had the protect effect on cerebral ischemia reperfiision from antioxidant and anti-apoptosis. [ABSTRACT FROM AUTHOR]

Objective: To explore the clinical effect of r-tpa combined mannitol in treatment of cerebral infarction caused by vascular diseases. Methods: The patients with acute cerebral infarction (ACI) within 6 hours were randomly divided into treatment group and control group with 60 cases in each group. The patients in treatment group accepted r-tpa combined mannitol, and the patients in control group accepted ligustrazine injection. The clinical efficacy and recovery of neurological function were measured after 15 days treatment. Results: The clinical effect of treatment group was 93.33 %, which was obviously higher than 78.33 % of control group with statistically significance (P<0.05). The CSS scores of two groups after treatment were obviously lower than before, and the treatment group was much lower than control group (P<0.05). The ADL scores of two groups after treatment were obviously higher than before, and the treatment group was much higher than control group (P<0.05). Conclusions: Using r-tpa combined mannitol has good effect in treatment of cerebral infarction caused by vascular diseases, which is safe and good at symptom improvement of later stage. [ABSTRACT FROM AUTHOR]