r-tpa 合并甘露醇治疗血管壁病变性脑梗死的临床疗效分析.

Objective: To explore the clinical effect of r-tpa combined mannitol in treatment of cerebral infarction caused by vascular diseases. Methods: The patients with acute cerebral infarction (ACI) within 6 hours were randomly divided into treatment group and control group with 60 cases in each group. The patients in treatment group accepted r-tpa combined mannitol, and the patients in control group accepted ligustrazine injection. The clinical efficacy and recovery of neurological function were measured after 15 days treatment. Results: The clinical effect of treatment group was 93.33 %, which was obviously higher than 78.33 % of control group with statistically significance (P<0.05). The CSS scores of two groups after treatment were obviously lower than before, and the treatment group was much lower than control group (P<0.05). The ADL scores of two groups after treatment were obviously higher than before, and the treatment group was much higher than control group (P<0.05). Conclusions: Using r-tpa combined mannitol has good effect in treatment of cerebral infarction caused by vascular diseases, which is safe and good at symptom improvement of later stage. [ABSTRACT FROM AUTHOR]