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By exploring the influence of viscous damper parameters in frame structure on the structural damping efficiency, the optimization problem of viscous damper parameters is studied. A three-dimensional finite element model is created using nonlinear dynamic time-history analysis for a frame structure. Various damping indices, such as additional damping ratio, reduction rate of vertex displacement, reduction rate of base shear force, and utilization rate of inter-layer displacement, are studied. The study begins with a sensitivity analysis to examine the influence of different viscous damping parameters on each index. Next, a response surface method is utilized to establish a relationship model between the viscous damping parameters and the indices. The fitting accuracy of this model is evaluated using the F test and the judgment coefficient R². Finally, an objective function for key damping indices is developed, and optimal parameters are determined through optimization techniques. The results demonstrate that the traditional sensitivity analysis method may not comprehensively consider the collective influence of different damping efficiency indices. On the other hand, the response surface method provides high fitting accuracy and good predictability and can serve as an effective optimization model. Moreover, after considering the stiffness of the supporting members matching the parameters of viscous dampers, the feasibility of the optimal damping parameters is proved by the practice of actual engineering cases. A set of simple and easy-to-operate parameter optimization design method of viscous dampers is proposed, which provides important guidance for damping design of frame structures in the future. [ABSTRACT FROM AUTHOR]

In order to eliminate the potential safety hazard of the mining area and the society caused by the ground subsidence disaster triggered by the continuous mining of the ore body, it is extremely important to carry out effective monitoring of the surface deformation in the mining area and research on the deformation mechanism. Therefore, based on the research background of Dengganshu mine section of Jinsha Mining Industry, the surface deformation monitoring of mining area is carried out using time-series interferometric synthetic aperture radar (InSAR) technology, and a three-dimensional model is established combining with the actual site to simulate the underground excavation process and obtain the distribution law of the displacement, stress and plastic zone of the surrounding rock of the mining area through FLAC3D, so as to comprehensively explore the deformation process and mechanism of the overlying rock and surface under the action of underground mining. The results show that the study area is in the state of non-uniform deformation, and the obvious deformation area is mainly distributed along the highway slope, and its cumulative shape variable fluctuates are in the range of 80~20 mm. Under the influence of mining, the surrounding rock of the goaf is mainly shear failure, and the plastic zone expands gradually with the increase of mining depth. With the advance of mining depth, under the action of its own gravity and mining stress, the magnitude and influence range of concentrated stress increase, and the disturbance influence on the surface is superimposed. At the end of the third mining, the movement range of surrounding rock in the goaf gradually increases and penetrates to the surface, causing surface deformation. The numerical simulation is consistent with the surface subsidence and deformation results shown by InSAR monitoring, which proves the rationality and reliability of the simulation process. The results show that the combination of InSAR monitoring and numerical simulation can directly reflect the formation process and mechanism of surface deformation in the mining area. This method can provide a reference for the monitoring of surface deformation disasters in similar underground mines and the prevention of potential disasters. [ABSTRACT FROM AUTHOR]

Amino acids and its metabolites have a regulatory effect on animal growth performance, immunity and product quality, which are vital to maintaining the normal growth and development of the animal body. The article discusses the research on amino acid regulation of cattle growth metabolism and product quality. The metabolism, physiological function and mechanism of amino acids are reviewed, and the application of amino acids in beef and dairy cattle production is also reviewed, which aims to provide a reference for the production and development of high-quality beef and high-quality milk for amino acids. [ABSTRACT FROM AUTHOR]

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Objective To understand the status of planned immunization in children with special health status and analyze its influencing factors. Methods The children aged 0-18 with special health status who were vaccinated in the hospital from September to December in 2019 were selected by drawing lots, and were divided into delayed vaccination group and normal vaccination group according to the interval of vaccination.The questionnaire survey and analysis were carried out in the two groups. Results The most common children with special health status in the delayed vaccination group were children with cardiovascular disease, premature infants, children with nervous system disease and children with immune system disease. The most common children with special health status in normal vaccination group were premature infants, children with cardiovascular disease,children with neonatal diseases and children with infectious diseases.In the delayed vaccination group, 99 (64.29%) family members thought that the child was in a sick state and delayed vaccination,and 45 (29.22%) family members were due to the advice of grassroots vaccination personnel. There were no significant differences in gender distribution of family members and incidence of adverse reactions to vaccination between the two groups (P >0.05) The diseases with long delay time were, immune system and cardiovascular. There were significant differences in the distribution of educational background,the source of vaccination information and the understanding of vaccination between the two groups (P <0.05). Conclusion Delayed vaccination is common in children with special health status. It is helpful to reduce the delay rate of vaccination by improving the awareness of family members, grassroots vaccination personnel, new-born pediatricians, obstetricians and gynaecologists on children with special health status and strengthening the publicity of vaccination for children with special health status. [ABSTRACT FROM AUTHOR]

目的 评估 1 470 nm半导体激光前列腺剜除术治疗良性前列腺增生症（BPH）的近期疗效。方法 回顾性分析2015年1~6月给予 1 470 nm半导体激光前列腺剜除术治疗的43例BPH患者的临床资料。监测和记录围术期,术后1、3个月最大尿流率（Qmax）、残余尿量（RUV）、国际前列腺症状评分（IPSS）、生活质量评分（QOL）等,并进行统计学分析,评价近期临床疗效。结果 43例患者均顺利完成手术,手术时间（95.0±21.3）min,术中出血量10~80 m L,无输血病例,术后膀胱冲洗时间（1.9±0.5）d,留置导尿管时间（3.1±0.8）d。术后1、3个月患者客观检查结果（Qmax、RUV）和主观症状（IPSS、QOL）均显著改善,差异均有统计学意义（P〈0.01）。结论 采用1 470 nm半导体激光前列腺剜除术安全、有效,具有损伤小、并发症少等优点,但其远期疗效仍需进一步研究。 [ABSTRACT FROM AUTHOR]

Forestry is an important part of China’s ecological and economic construction, especially the idea of carbon emission peak and carbon neutrality gives forestry a new mission. Taking the training of forestry professional master students in Anhui Agricultural University as an example, combined with the implementation of the “ double carbon” goal, this paper analyzed the problems and challenges encountered by students in the training process, and how to combine the implementation of the “double carbon” goal to reform and build while improving professional skills and practical innovation ability, in order to cultivate high-level, application-oriented and composite talents for meeting the needs of the country for the green development of forestry, and meet the needs of high-quality social development and ecological civilization construction under the “double carbon” goal. [ABSTRACT FROM AUTHOR]

In order to explore the hotspots and research trends of domestic research on biochar in tobacco agriculture in recent years, bibliometric methods were used to analyze papers about biochar application in tobacco planting research included in the China National Knowledge Infrastructure (CNKI). The numbers, annual distribution, author information, publications and research content were statistically analyzed, and the CiteSpace V visualization software was used to predict and analyze research hotspots. The results showed that a total of 114 journal papers and 81 dissertations on the application of biochar to tobacco planting were retrieved, including 8 doctoral dissertations and 73 master’ s dissertations. The institution with the most research in China was Henan Agricultural University, and Liu Guoshun was the scholar with the most published papers. Domestic research on tobacco biochar still lacked a stable core author group, and the number of core authors was small. Tobacco biochar application hotspots focused on tobacco quality, chemical composition and tobacco-growing soil. In recent years, research hotspots tended to be on the effects of biochar on soil microbial communities and heavy metals in tobacco leaves. [ABSTRACT FROM AUTHOR]

BACKGROUND: Obesity and its relevant chronic inflammation are important risk factors for inducing type 2 diabetes. This inflammatory response will further involve skeletal muscle, leading to an increase in catabolic and autophagic fluxes in skeletal muscle. Aerobic exercise is the mainstream mode of exercise in the prevention and treatment of type 2 diabetes, and may also has a certain protective effect on skeletal muscle. OBJECTIVE: To explore the effects and regulatory mechanisms of aerobic exercise on glucolipid metabolism, skeletal muscle inflammation and autophagy in type 2 diabetic rats. METHODS: Animal models of type 2 diabetes were established in rats by 8-week high-fat feeding combined with streptozotocin injection, and the experimental rats were then divided into normal control group, normal exercise group, diabetic control group and diabetic exercise group. The exercise group performed 4 weeks of aerobic exercise (16 m/min, 60 min/d, 5 d/wk). The levels of blood glucose, high-density lipoprotein, low-density lipoprotein and triglyceride in serum were measured by an automated biochemical analyzer. Serum insulin level was determined using enzyme-linked immunosorbent assay and the insulin resistance index and area under the glucose metabolism curve were calculated. The levels of interleukin 6 and tumor necrosis factor α in skeletal muscle were measured by enzyme-linked immunosorbent assay after 4 weeks of aerobic exercise, and the expression levels of forkhead box protein O3 (FoxO3), LC3 and p62 in skeletal muscle were measured by western blot assay. RESULTS AND CONCLUSION: The area under the glucose tolerance curve and insulin resistance index both increased significantly in type 2 diabetic rats (P < 0.001, P=0.025), and aerobic exercise significantly reduced the area under the glucose tolerance curve and insulin resistance index in the normal exercise group (P < 0.001, P=0.038) and diabetic exercise group (P < 0.001, P=0.004). Serum high-density lipoprotein significantly decreased (P=0.030), and lowdensity lipoprotein and triglyceride (P=0.027, P=0.014) levels significantly increased in the diabetic control group compared with the normal control group. Aerobic exercise significantly reduced triglyceride and low-density lipoprotein levels in the normal exercise group (P=0.019, P=0.008) as well as triglyceride levels in the diabetic exercise group (P=0.022). Both interleukin-6 and tumor necrosis factor α levels were significantly increased in the skeletal muscle of type 2 diabetic rats compared with the normal control group (P < 0.001, P=0.007), and aerobic exercise significantly reduced tumor necrosis factor α levels in the diabetic exercise group (P=0.017). The LC3-II/LC3-I was significantly increased in the skeletal muscle of type 2 diabetic rats compared with the normal control group. Aerobic exercise significantly increased the LC3-II/LC3-I in the normal exercise group (P < 0.001) and decreased the LC3-II/LC3-I, FoxO3 and p62 protein expression levels in the diabetic exercise group (P=0.026, P=0.050, P=0.048). To conclusion, type 2 diabetes model established by high-fat feeding combined with streptozotocin injection has obvious glycolipid metabolism disorder, and leads to inflammatory response and excessive activation of autophagy in skeletal muscle. Aerobic exercise can improve glycolipid metabolism, reduce local inflammation in skeletal muscle and inhibit autophagy, and finally play a protective role in skeletal muscle. [ABSTRACT FROM AUTHOR]

In order to establish the abundance-deficiency indices of soil nitrogen, phosphorus, potassium for tobacco planting soils in Guizhou Province, the correlation between the content of available nitrogen, phosphorus, and potassium nutrients in soil and the relative yield of tobacco leaves was analyzed based on fertilizing experiments we performed in Zunyi, Bijie and Qiandongnan. Based on the criteria that the relative yield of tobacco leaves was ≥95%, 85%-<95%, 65%-<85%, 50%-<65%, and <50% in the nutrient deficient plots, the corresponding soil available nutrients were divided into five grades, namely, extremely high, high, medium, low, and extremely low. The results showed that the average values of available nitrogen, available phosphorus, and available potassium were 122.66, 32.52, and 347.25 mg/kg, respectively. The average relative yields of tobacco leaves under nitrogen, phosphorus, and potassium deficiency treatments were 84.00%, 91.97%, and 101.00%, respectively. According to the calculation of the relationship equation, the indexes of alkali-hydrolyzable nitrogen in the extremely high, high, medium, low, and very low fertility grades of tobacco planting soils in Guizhou are ≥ 134.9, 123.8-<134.9, 101.5-<123.8, 84.8-<101.5, and <84.8 mg/kg, the indexes of available phosphorus are ≥34.5, 28.0-<34.5, 14.9-<28.0, 5.1-<14.9, and <5.1 mg/kg, and the indexes of available potassium are ≥324.0, 285.3-<324.0, 207.8-<285.3, 149.6-<207.8, and<149.6 mg/kg, respectively. It would provide reference and guidance for rational fertilization in Guizhou tobacco planting areas. [ABSTRACT FROM AUTHOR]

Field experiments were conducted to study the residue and degradation dynamics of atrazine in typical yellow soil tobacco fields in Guizhou Province,the occurrence of tobacco pesticide damage and the threshold and safety interval of tobacco damage was elucidated. The effects of soil environmental factors on the half-life of atrazine was analyzed. The results showed that atrazine inhibited the growth of tobacco significantly, which showed that the leaves were small, serious deformity, the old leaf tip vein began to yellow. The inhibition rates of plant height and leaf area were significantly positively correlated with atrazine dosage. The inhibition rates of plant height and leaf area increased with the increase of atrazine dosage. The degradation half-life of atrazine in typical yellow soil was 8. 45-11. 95 d, and the safe isolation period in the field should be longer than 48. 6 d. The degradation half-life of atrazine was significantly positively correlated with the content of soil organic matter, there was significant negative correlation with pH and available potassium, but no significant correlation with available phosphorus and available nitrogen. The results had great significance to the scientific application of herbicides and tobacco safety in the sorghum/ maizetobacco rotation area of yellow soil. [ABSTRACT FROM AUTHOR]

In theory, quasi phase match (QPM) can make full use of nonlinear optical coefficient of the crystal, and has no deviation effect, which has great advantages in optical frequency conversion. Lithium niobate crystal (LiNbO3, LN) has high nonlinear optical coefficient, wide optical range and low growth cost, causing the periodically poled lithium niobate crystal (PPLN) based on the design of ferroelectric domain structure is an ideal choice for QPM. At present, the most commonly used method for fabricating PPLN crystal is applied electric field method. In the fabrication process, the parameters of electrode structure are important for the poling process. Based on the electric field poling process under real-time monitoring and finite element analysis, this paper analyzed the spatial electric field distribution of different electrode structures. It is found that the electric field maximum appears at the edge of the electrode, the electric field distribution inside the electrode is relatively uniform. Based on this phenomenon, a design scheme of multi-channel electrode structure is proposed to achieve uniform distribution of electric field in poled area. By characterizing the duty cycle ratio of each channel, it is found that the duty cycle ratio of the inner eight channels are uniform and within 50% ±5%. Through the SHG experiment of crystals, it is found that the nonlinear conversion efficiency of the inner channel relative to the edge channel in the sample of ten-channel periodic poling is significantly improved and uniformly distributed. It is proved that the middle channels have a uniform poling structure with controllable duty cycle, which provides an effective design for generating uniform poling electric fields. [ABSTRACT FROM AUTHOR]

附设黏滞阻尼器后结构的附加阻尼比是进行减震结构设计的关键。基于目前计算附加阻尼比时应用得十分广泛的时程分析方法进行研究，首先从基本理论出发，分析基于特征向量法的快速非线性分析（FNA）方法、Ritz向量法的FNA方法、直接积分方法以及与3种计算方法对应的能量比法在附加阻尼比计算时所面临的主要问题及重要参数设置；然后通过一单自由度体系的振动台试验测试结果与各种计算方法的数值模拟结果进行对比分析，得到较为适合的附加阻尼比计算方法；最后将研究成果应用于实际工程结构，进一步验证所推荐方法和参数设置的正确合理性。研究旨在为今后广大一线减震设计工程师计算较为真实的附加阻尼比提供重要参考。

【Objective】The study aimed to explore the effects of biochar combined with nitrogen on morphological characteristics, root morphology, antioxidant activity, photosynthetic characteristics and Cd accumulation, accumulation and transport of Paulownia fortunei seedlings under Cd stress. 【Method】Taking ‘Paulownia fortunei 1201’ seedlings as materials, a combination of tissue culture and hydroculture tests was set up. The growth index, root parameters, photosynthetic gas parameters, antioxidant enzyme activity, MDA content, Cd accumulation, enrichment coefficient and transport coefficient of seedlings were measured by biochar and nitrogen single treatment and biochar combined with nitrogen treatment. 【Result】 (i) Under Cd stress, application of biochar and nitrogen could significantly increase plant height, biomass and root parameters, and their combination could achieve the optimal effect. (ii) SOD and CAT activities increased and MDA activities decreased in leaves and roots of Paulownia fortunei seedlings, POD activity decreased with increasing concentration under single application of biochar and nitrogen, and slightly increased with increasing concentration under combined application of biochar and nitrogen. (iii) Chla, Chlb and Chl (a+b) increased significantly, but Chl (a/b) had no significant change; Photosynthetic gas parameters (Pn, Tr, Ci, Gs) increased, WUE was the highest, and Ls decreased significantly. (iv) With the application of biochar or nitrogen, the Cd content and enrichment coefficient of Paulownia fortunei seedlings decreased, while the transport coefficient and Cd accumulation increased. (v) According to the correlation and PCA analysis of each index of seedlings, it was found that there was correlation among each index, and the overall promoting effect was biochar combined with nitrogen ＞ biochar ＞ nitrogen.【Conclusion】The application of biochar and nitrogen can improve the photosynthetic capacity of Paulownia fortunei seedlings, reduce the absorption of Cd, alleviate the toxicity of Cd, and then increase the biomass and promote the accumulation of Cd in various organs. [ABSTRACT FROM AUTHOR]

Objective: To investigate the predictive value of endotoxin (Endotoxin), procalcitonin (PCT) combined with neutrophil to lymphocyte ratio (NLR) in predicting urinary sepsis in patients after percutaneous nephrolithotomy (PCNL). Methods: 750 patients who underwent PCNL in the Department of Urology Surgery, The Second Affiliated Hospital of Xi’an Medical College and The First Affiliated Hospital of Air Force Military Medical University from May 2020 to May 2023 were selected as study subjects. Patients were divided into urinary sepsis group (n=45) and non sepsis group (n=705) according to the occurrence of urinary sepsis. The levels of serum Endotoxin, PCT, neutrophils and lymphocytes before PCNL were detected, and NLR was calculated. Serum Endotoxin, PCT levels and NLR were compared in two groups. The factors affecting the risk of urinary sepsis in patients after PCNL were analyzed by multivariate Logistic regression model. The clinical efficacy of serum Endotoxin, PCT combine with NLR in predicting urinary sepsis in patients after PCNL were analyzed by drawn receiver operating characteristic (ROC) curve. Results: Compared with non sepsis group, the serum Endotoxin, PCT and NLR in urinary sepsis group were higher (P＜0.05). Multivariate Logistic regression model analysis showed that, elevated serum Endotoxin, elevated PCT, elevated NLR, positive urine white blood cells, preoperative fever and staghorn calculi were independent risk factors for urinary sepsis in patients after PCNL (P＜0.05). The results of ROC curve analysis showed that, the area under the curve (AUC) of serum Endotoxin, PCT combine with NLR in predicting urinary sepsis in patients after PCNL was 0.913, which was higher than that of the above indicators alone. Conclusion: The increase of serum Endotoxin, PCT and NLR before PCNL may be relate to the occurrence of urinary sepsis in patients after PCNL. Elevate serum Endotoxin and PCT levels, elevate NLR, preoperative fever, positive urine white blood cells and staghorn calculi are risk factors for urinary sepsis in patients after PCNL. Serum Endotoxin, PCT combine with NLR detection has a high predictive value for urinary sepsis in patients after PCNL. [ABSTRACT FROM AUTHOR]

To discuss the optimizing strategy in screening for the asymptomatic carotid artery stenosis (aCAS) or asymptomatic intracranial artery stenosis (aICAS) and the precise strategy in prevention for stroke based on the biomarkers and the imaging manifestations. The prevalence of aCAS was about 1.5% and the risk scores of aCAS were helpfull in the screening. The prevalence of aICAS was 6.9%～12.8%, according to the different study population and the screening tools. In patients with aCAS or aICAS, the severity of the vascular stenosis and the stability of the tube wall will affect the risk for stroke. Intraplaque hemorrhage was proved to increase the risk of incidence in stroke or coronary heart disease in the recent study. The cerebral blood flow and the cerebral perfusion decreased in the patients with aCAS or aICAS, which increased the risk of dementia or cognitive impairment with one to three times. Whether the patients with aCAS will benefit from carotid endarterectomy (CEA) or carotid artery stenting (CAS) need reevaluation as the drug therapy has made great progress. It play an important role to select a suitable patient and to reduce the complication of operation when making decisions. For the patients with aICAS, especially those with severe stenosis or multiple stenosis, progressive intracranial atherosclerosis disease, silent brain infarction within the brain territory distal to the aICAS, antiplatelet therapy and statins could be beneficial, with the consideration of cerebral hemorraghe or other adverse effects. [ABSTRACT FROM AUTHOR]

BACKGROUND: With the aging of population, sarcopenia in type 2 diabetes mellitus has gradually emerged in front of people. Increasing physical activity is an important approach to prevent and treat type 2 diabetes mellitus and its related sarcopenia. However, current intervention plan, effect evaluation and mechanism of different physical activities in type 2 diabetes-related sarcopenia are still not detailed. OBJECTIVE: To analyze the intervention program, effect evaluation and mechanism of physical activity in type 2 diabetes-related sarcopenia, thereby providing theoretical basis and practical suggestions for physical activity to improve the disease. METHODS: Search terms included “Diabetes Mellitus; T2DM; Sarcopenia; Muscular Atrophy; Exercise; Training; physical activity” in English and Chinese. PubMed and CNKI were searched for relevant literature published from January 1986 to February 2022, including review papers, research papers and meta-analysis. Finally, 53 literatures were included for the review. RESULTS AND CONCLUSION: Appropriate increase in non-leisure physical activity (daily steps above 5 401 per day) can reduce the probability of sarcopenia and maintain physical exercise function in elderly type 2 diabetes patients. Increasing leisure physical activity can prevent the incidence of sarcopenia in elderly type 2 diabetes patients, and any regular physical exercise can be effective. Resistance exercise is significantly superior to aerobic exercise in the prevention and treatment of type 2 diabetes-related sarcopenia. A resistance exercise of moderate intensity and above (3 times a week, 70%-85% 1RM) can effectively increase muscle mass and strength performance in type 2 diabetes patients with sarcopenia, while aerobic exercise mainly delays skeletal muscle loss. Combining resistance exercise with aerobic exercise, nutritional intervention and health education can increase patient compliance and improve treatment efficacy. Resistance exercise mainly improves protein synthesis by activating IRS-PI3K-Akt, mTORC1, p70S6K and 4EBP1 signaling pathways, and improve muscle mass and functions by stimulating muscle satellite cell proliferation and differentiation. Aerobic exercise mainly delays muscle loss by inhibiting ubiquitin protein ligases Atrogin-1 and MuRF1 and skeletal muscle autophagy. [ABSTRACT FROM AUTHOR]

Objective To observe and analyze the clinical efficacy of Platelet-rich Plasma (PRP) therapy combined with Henggu bone injury healing agent in the treatment of knee osteoarthritis (KOA). Methods A total of 113 KOA patients admitted to this hospital from May 2018 to May 2021 were selected and randomly divided into conventional treatment group (n=36), PRP treatment group (n=37) and combined treatment group (n=40) according to the treatment plan. The conventional treatment group received conventional nonsurgical treatment, the PRP treatment group received knee cavity PRP injection treatment, and the combined treatment group received PRP injection combined with Henggu bone injury healing agent treatment. The pain, clinical efficacy, inflammatory factor levels and adverse reactions were compared among the three groups. Results After treatment, the visual analogue scale (VAS) scores, the levels of matrix metalloproteinase 1 (MMP-1), and the hypersensitive C-reactive protein (hs-CRP) in the three groups were decreased gradually (P <0. 05), and the decrease of the PRP treatment group and the combined treatment group were more obvious than the conventional treatment group (P <0. 05). The Hospital for Special Surgery (HSS) score and effective rate of the PRP treatment group and the combined treatment group were significantly higher than those of the conventional treatment group, and the difference between the combined treatment group and the conventional treatment group was more statistically significant (P <0. 05). The rate of adverse reactions in the combination treatment group was higher than that in the PRP treatment group and the conventional treatment group, the difference was statistically significant (P <0. 05). Conclusion PRP combined with Henggu bone injury healing agent is effective and safe in the treatment of knee osteoarthritis, and the long-term effect is better. [ABSTRACT FROM AUTHOR]

The clinical diagnosis and molecular biological characteristics of a case of Gallinula chloropus infected with digestive tract aspiration and death were studied.In order to identify the isolated Echinostoma by molecular biology technology,we recorded the symptoms of the digestive tract and the appearance of the body.The inflammatory changes in pathological tissues were studied in different degrees.The fragment size of the amplified ITS was 744 bp,and the isolated strain was close to E.trivolvis(GQ463127.1)and the homology was 92.90%.The study of this case provides information on the clinical diagnosis of digestive tract fluke disease in Gallinula chloropus,and also provides a molecular reference for the artificial breeding of G.chloropus and the classification of its pathogenic factors. [ABSTRACT FROM AUTHOR]

【Objective】To explore the codon usage pattern of Fusarium oxysporum genome-wide and to assess the factors influencing the codon composition and coding characteristics. 【Methods】Using software CodonW and R to analyze the codon preference and its influencing factors on genome-wide data from F. oxysporum. 【Results】A total of 18 125 sequences was obtained. The average GC content of F. oxysporum was 51.46%. The ENC value ranged from 24.31 to 61.00, and 94.41% of the ENC values were more than 45. Leucine and Alanine were the major amino acids, and accounted for 8.86% and 8.29%respectively. While Tryptophan and Cysteine accounted for only 1.61% and 1.34% respectively. F. oxysporum had 33 highfrequency codons and 19 optimal codons, with the majority of the codons ending in G/C. The correlation study of basic codon parameters revealed that the correlation between GC1 and GC2 was extreme significant（P ＜0.01), while the correlation between GC3 and ENC was the strongest（P＜0.01).【Conclusion】Natural selection is the primary factor influencing the codon preference of Fusarium oxysporum. The correlation between GC3 and ENC was the strongest. 33 high-frequency codons and19 optimal codons primarily ending in G/C. [ABSTRACT FROM AUTHOR]

Clinical diagnosis, hematology, X-ray examination, pathological autopsy and histopathological methods were used to detect and analyze the body surface masses of a captive rat snake(Ptyas mucosus). X-ray examination showed that there were two masses on the back of the snake, with obvious boundaries differing from the surrounding tissues, and there were parenchyma and calcification in the body. Pathological autopsy revealed that the capsule of the tumor was ruptured. The cut surface of the small tumor was while and hard in texture. The mass of the large tumor was soft and had a foul odor. The interior showed a layered structure. The decayed part of the outer layer was accompanied by a small amount of purulent hyperplasia. Microscopically, a large number of tissue-like cells with eosinophilic cytoplasm can be seen proliferating, and a large number of pink, multinucleated giant cells and a large number of calcification foci can be seen locally, with a loose structure and a large number of telangiectasias. After pathological diagnosis, combined with clinical examination and analysis, the snake was diagnosed as rhabdomyosarcoma. The research results can provide reference for veterinarians to diagnose clinical rhabdomyosarcoma in exotic pets. [ABSTRACT FROM AUTHOR]

The experiment was conducted to investigate the effect of different density chicoric acid on hematology index and myocardial injury in SD rats. 60 healthy 6~8 w of agemale SD rats with the body weight of (192.00±7.35) g were selected. After 2 w of adaptive feeding, SD rats were randomly divided into a control group and three different density CA group (10, 20 and 40 mg/kg group), with 15 animals in each group. The experiment lasted for 49 d. The results showed that compared with the control group, feeding CA could significantly increased the blood oxygen uptake index blood oxygen partial pressure (PO2), blood oxygen saturation (SO2) ( P <0.05), oxygen-carrying index red blood cell count (RBC), hematocrit (HT), hemoglobin concentration (Hb), average hemoglobin concentration (MCHC), average hemoglobin content (MCH) ( P <0.05). CA could significantly increased the pH value of the acid-base balance index ( P <0.05), and reduced the partial pressure of carbon dioxide (PCO2), the content of anion gap (AG), the total amount of carbon dioxide (TCO2) significantly ( P <0.05). CA reduced the number of vascular injury indexes platelets (PLT) and platelet packed product (PCT) significantly ( P <0.05). CA increased the cardiac contractility indexes HWI and LVMI significantly ( P <0.05). CA reduced the levels of myocardial injury indexes lactate dehydrogenase (LDH) and creatine kinase (CK) significantly ( P <0.05). The experiment indicates that CA can improve SD rats' blood oxygen-carrying capacity, regulate acid-base balance, improve blood vessel damage, promote cardiac contraction, alleviate myocardial damage, and enhance SDrats'adaptabilitytohigh-altitudeandlow-oxygen environments.The 40mg/kggrouphasthebesteffect. [ABSTRACT FROM AUTHOR]

为从机理上探讨增加光照对绿尾虹雉繁殖性能的影响,在繁殖期对笼养条件下的绿尾虹雉进行了人工补充光照试验。选择体重大小相近的绿尾虹雉成龄个体8只(4♂、4♀),随机分成1个对照组和1个试验组,每组4只(2♂、2♀),每组2个重复,每重复2只(1♂、1♀)。对照组为自然光照; 试验组为自然光照结合人工补充光照达到每天16 h(16L:8D)的光照时间。结果表明:试验组血液生理指标与对照组差异不显著(P>0.05); 试验组血液生化指标的总蛋白、白蛋白、球蛋白、谷丙转氨酶、谷草转氨酶、碱性磷酸酶、钙、无机磷、胆固醇、甘油三酯的含量高于对照组(P>0.05),尿酸含量低于对照组(P>0.05); 试验组繁殖期的日平均采食量高于对照组(P>0.05)。本实验的结论是:在繁殖期利用自然光照结合人工补充光照(16L:8D)可增加绿尾虹雉日平均采食量,但对血液生化指标水平有一定影响,对绿尾虹雉血液生理指标影响不明显。

为了探究在不同生活环境的天鹅肠道菌群的差异，我们从3个地点收集了4组天鹅的粪便样品，A组样品来自河南农业大学的黑天鹅（n=3），B组样品为郑州市动物园的黑天鹅（n=4），C组（n=4）和D组（n=4）样品来自迁徙至三门峡越冬的大天鹅。使用粪便DNA提取试剂盒提取粪便DNA，采用Illumina Hiseq平台进行细菌16S rRNA 基因V4—V5区域高通量测序，将下机数据经过处理和拼接后用于研究肠道菌群的差异。结果显示，A组的OTU个数显著高于其他组，OTU主成分与其他组有较大差异；alpha多样性分析显示A组菌群丰度和多样性均显著高于其他组；beta多样性显示C组和D组物种组成较为相似。通过肠道菌群相对丰度分析，各组在门水平上和属水平上的核心菌群构成差异较大。门水平上，厚壁菌门和变形菌门是4组天鹅共有的优势菌群，两门细菌相对丰度之和在每组均高于45%。属水平上，A组的核心菌属为氢噬胞菌属（462%）、假鱼腥藻属（407%）和普雷沃菌属（402%）。B组的核心菌属为拟杆菌属（3256%），链球菌属和肠球菌属细菌为C组和D组的核心菌属，两属细菌相对丰度之和分别为每组的5174%和2243%。值得注意的是，在C组和D组的优势菌属中，链球菌属、梭杆菌属、肠球菌属、弯曲菌属、梭菌属的一些细菌能感染人类并导致疾病。同时发现迁徙天鹅的能量相关代谢通路丰度低于人工喂养天鹅。本研究结果表明，在不同地点生活的天鹅肠道菌群存在差异，同时发现迁徙天鹅带有人兽共患细菌，证明了饮食营养和栖息地环境会影响天鹅肠道菌群组成，迁徙天鹅有潜在的公共卫生安全隐患。我们首次对天鹅肠道菌群进行了研究，为进一步研究天鹅肠道菌群多样性和天鹅在不同生活环境中的适应机制提供科学依据，并为加强公共卫生安全提供理论支持。

装配式钢结构建筑是建造方式的一种改革,更是建筑业落实党中央、国务院提出的推动供给侧结构性改革和绿色低碳可持续发展战略的一个重要举措。但是目前钢结构建筑产业化在工程应用及市场推广上仍面临多方面的困难,国内仅7个地区出台相关政策指导意见,学术研究大都集中在钢结构建筑产业化的发展阻力上,在关键技术、经济成本、产业链等方面还需继续深入研究。对钢结构建筑产业化发展的研究情况进行综述,分析了当前研究现状和不足,归纳了影响钢结构建筑产业化发展的宏观环境、政策体系、技术体系、产业组织4类关键因素。同时,对国内相关政策文件进行梳理,提出了钢结构建筑产业化发展的推进机制,要明确发展目标、落实主要任务、完善政策支持、强化保障措施,以推动钢结构建筑产业化持续健康发展。

玉溪公租房高度为94.7m,最大高宽比为3.96。上部结构为剪力墙结构,设计时采用布置长剪力墙的方法,有效提高了上部结构刚度,结构自振周期减小到1.536s,同时隔震层布置剪切模量较低的隔震橡胶支座,隔震后结构自振周期延长至4.412s。隔震层设计成框支层,隔震支墩分布均匀,隔震橡胶支座压应力更加均匀,提高了隔震橡胶支座的使用效率,也提高了地下室结构柱网的规则性,提升了地下室的使用功能。通过采用直径1 000mm及以上隔震橡胶支座,提高了隔震设计的可靠度。使用三向地震动输入进行隔震分析,实现将上部结构水平地震作用降低50%的效果,各项指标均满足规范要求。通过插值法计算最小地震剪力系数,使得结构经济性进一步得到优化。

200 equivalent linearization methods, composed of 10 calculation methods for equivalent period and equivalent damping ratios, 4 damping scaling factors and 5 acceleration response spectra, were used to estimate the displacement response of 100 single degree of freedom models of seismic isolated structures with initial natural periods between 0.6-1.5 s and yield displacements between 2-11 mm. The results were compared with those from time-history analysis. The investigations show that the seismic response calculated by artificial waves matching the Chinese acceleration spectrum is larger than those calculated by other artificial waves matching the American, Japanese and European acceleration spectra, therefore the calculation has the high safety margin. Damping scaling factor is well matched with acceleration response spectrum in American, Japanese and European codes, and high precision result can be obtained by the adoption of reasonable equivalent parameters in equivalent linearization method. It’s not accurate to analyze the isolated structure by using equivalent linearization method including Chinese acceleration response spectrum with the existing equivalent parameters and damping scaling factor. [ABSTRACT FROM AUTHOR]

褐马鸡过去主要见于山西吕梁山脉和河北小五台地区,但近年来的调查表明,目前褐马鸡的分布包括4个省市的33个县区,其中三处地点是90年代刚发现有褐马鸡分布.