351. Renal function changes in diabetes.
- Author
-
Mogensen CE
- Subjects
- Antihypertensive Agents therapeutic use, Arginine pharmacology, Diabetes Mellitus, Type 1 complications, Diabetes Mellitus, Type 1 prevention & control, Glomerular Filtration Rate drug effects, Glucose metabolism, Humans, Insulin therapeutic use, Kidney Function Tests, Kidney Glomerulus physiopathology, Lysine pharmacology, Male, Organ Size, Proteinuria complications, Proteinuria therapy, Diabetes Mellitus physiopathology, Diabetes Mellitus, Type 1 physiopathology, Diabetic Nephropathies prevention & control, Kidney physiopathology
- Abstract
The present studies show that a number of functional abnormalities are present in the kidney in early diabetes, especially during poor regulation. Normalization of these functions and changes in renal and glomerular size are found during complete diabetes control. The results further support the idea that great efforts should be made to maintain the best possible control situation in diabetic patients. Our studies also indicate that antihypertensive therapy may be beneficial for young, proteinuric diabetics and may postpone the stage of renal insufficiency.
- Published
- 1976