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Since the 1930s, Gestalt therapy developed from psychoanalysis integrating various influences: Gestalt psychology and the holistic perspective, phenomenology and American pragmatism, the artistic avant-garde of Berlin and later of New York, and social and political activism. Two of the core aspects of this approach are the concept of self as emerging process and the field perspective. In this view, the experiences of both therapist and patient are influenced by the intrinsic tensions of the therapeutic situation, i.e., by the intentionalities of the field that tend to complete the assimilation process of what has not been fully experienced. Psychopathology emerges in the therapeutic encounter as an absence, i.e., as a difficulty in being fully present. The therapeutic process implies an emotional as well as corporeal participation on the part of the therapist, who allows for the emergence of what in the field pushes to take shape and be integrated. A clinical vignette is used in order to exemplify three paradigms that can describe the therapeutic change (the mono-personal, the bi-personal, and the field theory paradigms), and a detailed clinical case is discussed according to the field theory paradigm. [ABSTRACT FROM AUTHOR]

BACKGROUND: The environmental effects of heavy metal pollutants in soil are closely related to their inorganic valence. The determination of the valences of As, Cr, Sb and Se elements is of great significance, but due to the easy conversion between the valences, the determination is difficult and the degree of standardization is low. The geological industry standard DD200S-3 recommends the use of ion exchange resin separation, atomic fluorescence spectrometry to determine the valences of As, Sb, and Se, and graphite furnace atomic absorption spectrometry (GFAAS) to determine the valence of Cr. The preparation of these methods is cumbersome, the number of measurements is large, the workload is large, and the existence of other element forms can also cause errors in the results. OBJECTIVES: To establish a set of methods suitable for determining the valences of water-soluble and exchangeable As, Cr, Sb and Se in soil samples. METHODS: The valences of As, Sb and Se were separated and determined by HPLC-HG - AFS after 30 min extraction in a water bath of 50°C. The processes were simpler and more accurate than the recommended subtraction processes by AFS. To avoid the masking action of some extracting agent, the method of selective determination of Sb(III), Sb(V), Se(V) and Se(VI) by AFS was developed, which had the advantage of low instrument cost. As for Cr(III) and Cr( VI), after separation by ion exchange resin, they were determined by ICP-MS, which has higher sensitivity than the recommended GFAAS. RESULTS: The detection limits of As(III). As(V), Cr(III), Cr(VI), Sb (III). Sb (V), Se (V) and Se(V) was 0. 02μg/g, with the RSD of 3.8% - 10. 7% and the recovery of 91. 0%-106. 0%. These methods were successfully applied to the analysis of geological samples, and all indices met the quality requirements of DD2005-3. CONCLUSIONS: Compared with non-chromatographic methods, newly established methods by HPLC-HG - AFS can determine multiple components simultaneously. At the same time, preliminary studies have shown that the valence content of elements in the soil is not high, and lacks correlation with the total amount of soil. [ABSTRACT FROM AUTHOR]

In light of contemporary theories of the development of the self and infant research studies, the author proposes a reinterpretation of the lapsus phenomenon. The lapsus phenomenon was conceived by Freud as a disturbance due to the emergence of psychic contents that have been repressed because they are unacceptable on the level of consciousness. The current interpretation conceives the lapsus as a signal of expression of the intentionally oriented nascent self. These ideas will be considered through the lens of a clinical case that highlights and explicates this phenomenon. [ABSTRACT FROM AUTHOR]

Mercury and selenium concentrations and Se:Hg molar ratio in edible muscle and hepatopancreas of the crab Callinectes arcuatus from coastal lagoons of northwest Mexico were determined using atomic absorption spectrophotometry. The three coastal lagoons were Santa María La Reforma (SMLR), Urías (UR), and Huizache-Caimanero (HC); samplings were carried out from December 2016 to October 2017. The mercury ranges in the muscle of C. arcuatus in SMLR, UR, and HC lagoons were 0.31–0.52, 0.15–0.45, and 0.22–0.55 μg g−1, respectively. In hepatopancreas, the values ranged from 0.08 to 0.15, 0.06 to 0.15, and 0.05 to 0.12 μg g−1 in SMLR, UR, and HC lagoons, in that order. For selenium concentrations in C. arcuatus muscle, the ranges 11.64–20.14, 14.88–19.71, and 15.27–29.51 μg g−1 were determined in SMLR, UR, and HC lagoons, respectively. While for hepatopancreas, the ranges were 34.34–44.13, 27.77–40.45, and 15.16–49.80 μg g−1, in that order. No significant relationships (p > 0.05) between mercury and selenium concentrations (in white meat and hepatopancreas) were observed in C. arcuatus carapace width and length. Se:Hg molar ratio values were 98.1 ± 20.8, 171.4 ± 81.6, and 176.8 ± 51.2 for SMLR, UR, and HC lagoons, in that order. This high ratio (> 1) in C. arcuatus edible muscle indicated that selenium concentration was sufficient to neutralize possible mercury toxicity, so it does not represent danger to humans when it is consumed. [ABSTRACT FROM AUTHOR]

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The main focus of current research is on the synthesis and anticorrosive activity of novel heterocyclic compounds tert-butyl 4-[(4-methyl phenyl) carbonyl] piperazine-1-carboxylate [TBMPCPC]. Electrochemical, quantum chemical, and surface characterization studies at elevated temperatures (303–333 K) for carbon steel in 1M HCl solution studied this molecule's corrosion inhibition property. It is observed from the results of electrochemical studies that the TBMPCPC may be able to effectively protect the steel plate surface with an inhibition efficiency of 91.5 % at 25 ppm in corrosive media. The corrosion inhibition depends on concentration, as concentration also increases inhibition efficiency due to the strong and spontaneous adsorption on the metal's surface. The Tafel polarization measurements concluded that the inhibitor works as a mixed form to protect the carbon steel in the bulk solution from corrosion. The adsorption of the TBMPCPC onto the metal surface was in reliable with the isothermal model of the Langmuir adsorption. The scanning electron microscopy clearly showed that the inhibitor was substantially deposited on the metal surface, indicating substantial inhibition. The surface morphology of carbon steel in the absence and existence of an inhibitor in 1 M HCl is also studied using the Atomic Force Microscopic method.

Este artigo aborda um produto das relações e demandas em escala dos atores sociais, isto é, os indivíduos e as instituições nas esferas do público, eclesiástico e laico, envolvidas no processo da implantação da Praça e Catedral da Sé na antiga área central de São Paulo, entre os anos de 1903 e 1913. Colocando em tela o fenômeno da demolição no fazer urbano, buscamos compreender como para se realizar essa intervenção na paisagem urbana, com a feitura de novas estruturas urbanas como a praça e a catedral, demandou-se um circuito de propostas, definições e um aparelhamento que pensou, primeiramente, a feitura de uma cidade em demolição. Ou seja, um processo para o desmonte de estruturas antigas e preexistentes, que teve como resultado o desalojamento de inúmeros ocupantes da área-alvo. Desse modo, enfocamos uma arquitetura coletiva dos arranjos político, simbólico e de cifras em torno da obra, analisando o seu impacto em nível de uma rede reveladora da face social do processo, através dos nomes, dos acordos e negociações, tensões e contestações ao discurso acerca da realização da obra, que não se encontram assimiladas pela historiografia. Nesse sentido, agregamos uma documentação primária inédita, base da nossa reflexão, oriunda do Departamento de Desapropriações de São Paulo.

This paper offers a multivariate analysis of the alternation between 2 Spanish constructions traditionally considered as impersonal, namely uno and se, in 3 different spoken language genres. The proposed analysis will show that, while the traditionally described syntactic factors related to this alternation and to the analysis of each of these forms account for part of the alternation, it is the much less studied pragmatic-discursive factors that offer a better explanation. Moreover, we will show the crucial role of genre variation and of differences as to intersubjective functioning for accounting for the alternation between these two constructions.

Atomic layer deposition (ALD) is widely used in the semiconductor and materials industries for depositing thin films. Here, we describe a holder/container for performing ALD on particles that does not require agitation. This device contains a broad, shallow, circular recess that holds the particles. Two different frits and combinations of stacked meshes were explored as a cover to this holder to restrict the movement of the particles while still allowing good conductance of the ALD reagent gases. A mathematical discussion of the diffusion through the frits and stacked meshes is presented. As confirmed by spectroscopic ellipsometry (SE) on planar witness silicon shards, consistent, high‐quality film growth took place inside and outside the holder. The performance of the holder was demonstrated with ~5‐μm zirconia particles that were coated with alumina from trimethylaluminum (TMA) and water, and with zinc oxide from diethylzinc (DEZ) and water. Deposition on different amounts of particles was investigated (50, 100, 200, and 500 mg). Parasitic chemical vapor deposition (CVD) appeared to be present when a greater number of particles or meshes were used. ALD coating on particles was also confirmed by X‐ray photoelectron spectroscopy (XPS), transmission electron microscopy (TEM), and energy‐dispersive X‐ray spectroscopy (EDS). [ABSTRACT FROM AUTHOR]

This study aimed to Modify the PEEK surface using Fractional CO2 laser in different range of parameters to change the surface topography regarding roughness and wettability to enhance osseointegration. A PEEK block (Ceramill PEEK 98X20 N-JUVORA dental innovations, UK) was used to prepare substrate. By CAD-CAM system, PEEK was cut into discs (2 mm thickness and 10 mm diameter). the discs were smoothed by silicon carbide paper of 500 grit and a rotation motion, polishing machine at 200 rpm for one minute used to polish the discs, finally cleaned with ethanol alcohol using ultrasonic cleaner. Different parameters were tested to study their effects on PEEK surface; therefore, several trails were done using Fractional CO2 laser device. Surfaces of the irradiated PEEK discs were examined microscopically at different magnification power. Then SEM was used. Then, PEEK samples were scanned by (EDS). Range of powers were used (2, 4, 6, 8, 10, 12) W The distance between spots was 0.2mm and 0.2 ms pulse duration to ensure maximum coverage of laser effect. The energy range was (4 - 25) which wasn't enough to produce any effect. To test the effect of pulse duration different values were also studied starting from 0.2ms then increase the pulse duration. 0.4,0.6,0.8 ms to increase the energy per pulse accordingly. Starting from short pulse duration up to 0.6ms there was no effect even when the power increased. At 0.8 ms pulse duration, the effect was recognized on the specimen surface. The collected data of previous trials direct the operator to reduce pulse duration to have best criteria, including surface roughness, wettability, without carbonization or cracks. Conclusions: Successful modification of PEEK surface can be done with fractional CO2 laser. Laser parameters as power, pulse duration, distance between spotes and number of scans are key factors induced different range of effect considering material's properties. [ABSTRACT FROM AUTHOR]

Japan is a country with an approximate 10% prevalence rate of carbapenem-resistant Pseudomonas aeruginosa (CRPA). Currently, a comprehensive overview of the genotype and phenotype patterns of CRPA in Japan is lacking. Herein, we conducted genome sequencing and quantitative antimicrobial susceptibility testing for 382 meropenem-resistant CRPA isolates that were collected from 78 hospitals across Japan from 2019 to 2020. CRPA exhibited susceptibility rates of 52.9%, 26.4%, and 88.0% against piperacillin-tazobactam, ciprofloxacin, and amikacin, respectively, whereas 27.7% of CRPA isolates was classified as difficult-to-treat resistance P. aeruginosa . Of the 148 sequence types detected, ST274 (9.7%) was predominant, followed by ST235 (7.6%). The proportion of urine isolates in ST235 was higher than that in other STs ( P = 0.0056, χ 2 test). Only 4.1% of CRPA isolates carried the carbapenemase genes: bla GES (2) and bla IMP (13). One ST235 isolate carried the novel bla IMP variant bla IMP-98 in the chromosome. Regarding chromosomal mutations, 87.1% of CRPA isolates possessed inactivating or other resistance mutations in oprD , and 28.8% showed mutations in the regulatory genes ( mexR , nalC , and nalD ) for the MexAB-OprM efflux pump. Additionally, 4.7% of CRPA isolates carried a resistance mutation in the PBP3-encoding gene ftsI . The findings from this study and other surveillance studies collectively demonstrate that CRPA exhibits marked genetic diversity and that its multidrug resistance in Japan is less prevailed than in other regions. This study contributes a valuable data set that addresses a gap in genotype/phenotype information regarding CRPA in the Asia-Pacific region, where the epidemiological background markedly differs between regions., Competing Interests: The authors declare no conflict of interest.

Selenium (Se) is a crucial micronutrient for human health. Plants are the primary source of Se for humans. Selenium in the soil serves as the primary source of Se for plants. The soil contains high total Se content in large areas in Guangxi, China. However, the available Se is low, hindering Se uptake by plants. Microorganisms play a pivotal role in the activation of Se in the soil, thereby enhancing its uptake by plants. In this study, selenobacteria were isolated from Se-rich soils in Guangxi. Then two selenobacteria strains, YLB1-6 and YLB2-1, representing the highest (30,000 μg/mL) and lowest (10,000 μg/mL) Se tolerance levels among the Se-tolerant bacteria, were selected for subsequent analysis. Although the two selenobacteria exhibited distinct effects, they can significantly transform Se species, resulting in a decrease in the soil residual Se (RES-Se) content while concurrently increasing the available Se (AVA-Se) content. Selenobacteria also enhance the transformation of Se valencies, with a significant increase observed in soluble Se 6+ (SOL-Se 6+ ). Additionally, selenobacteria can elevate the pH of acidic soil. Selenobacteria also promote the uptake of Se into plants. After treatment with YLB1-6 and YLB2-1, the Se content in the aboveground part of Chinese flowering cabbage increased by 1.96 times and 1.77 times, respectively, while the Se accumulation in the aboveground part of the plant significantly increased by 104.36% and 81.69%, respectively, compared to the control. Further whole-genome sequencing revealed the genetic difference between the two selenobacteria. Additionally, 46 and 38 candidate genes related to selenium utilization were identified from YLB1-6 and YLB2-1, respectively. This work accelerates our understanding of the potential molecular mechanism of Se biofortification by selenobacteria. It also provides microorganisms and gene targets for improving crop varieties or microorganisms to exploit the rich Se source in soil., Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. The handling editor MS declared a past collaboration with the author Y-XL., (Copyright © 2024 Liao, Li, Xing, Liang, Jiang, Liu and Huang.)

The exotic even–even isotopic chains from Z = 3 2 to Z = 3 8 are investigated by means of the relativistic Hartree–Bogoliubov (RHB) approach with the explicit Density Dependent Meson-Exchange (DD-ME2) and Density-Dependent Point-Coupling (DD-PC1) models. The classic magic number N = 5 0 is reproduced and the new number N = 7 0 is predicted to be a robust shell closure by analysing several calculated quantities such as: two-neutron separation energies, two-neutron shell gap, neutron pairing energy, potential energy surface and neutron single particle energies. The obtained results are compared with the predictions of finite range droplet model (FRDM) and with the available experimental data. A reasonable and satisfactory agreement between the theoretical models and experiment is established. [ABSTRACT FROM AUTHOR]

Hypoxia induces cell death through excessive production of reactive oxygen species (ROS) and calcium (Ca2+) influx in cells and TRPM2 cation channel is activated by oxidative stress. Zinc (Zn), selenium (Se), and glutathione (GSH) have antioxidant properties in several cells and hypoxia-induced TRPM2 channel activity, ROS and cell death may be inhibited by the Zn, Se, and GSH treatments. We investigated effects of Zn, Se, and GSH on lipid peroxidation (LPO), cell cytotoxicity and death through inhibition of TRPM2 channel activity in transfected HEK293 cells exposed to hypoxia defined as oxygen deficiency. We induced four groups as normoxia 30 and 60 min evaluated as control groups, hypoxia 30 and 60 min in the HEK293 cells. The cells were separately pre-incubated with extracellular Zn (100 µM), Se (150 nM) and GSH (5 mM). Cytotoxicity was evaluated by lactate dehydrogenase (LDH) release and the LDH and LPO levels were significantly higher in the hypoxia-30 and 60 min-exposed cells according to normoxia 30 and 60 min groups. Furthermore, we found that the LPO and LDH were decreased in the hypoxia-exposed cells after being treated with Zn, Se, and GSH according to the hypoxia groups. Compared to the normoxia groups, the current densities of TRPM2 channel were increased in the hypoxia-exposed cells by the hypoxia applications, while the same values were decreased in the treatment of Zn, Se, and GSH according to hypoxia group. In conclusion, hypoxia-induced TRPM2 channel activity, ROS and cell death were recovered by the Se, Zn and GSH treatments. [ABSTRACT FROM AUTHOR]

Selenium (Se) is an essential element for humans and animals and its deficiency in the diet is a global problem. Crop plants are the main source of Se for consumers. Therefore, there is much interest in understanding the factors that govern the accumulation and distribution of Se in the tissues of crop plants and the mechanisms of interaction of Se absorption and accumulation with other elements, especially with a view toward optimizing Se biofortification. An ideal crop for human consumption is rich in essential nutrient elements such as Se, while showing reduced accumulation of toxic elements in its edible parts. This review focuses on (a) summarizing the nutritional functions of Se and the current understanding of Se uptake by plant roots, translocation of Se from roots to shoots, and accumulation of Se in grains; and (b) discussing the influence of nitrogen (N), phosphorus (P), and sulfur (S) on the biofortification of Se. In addition, we discuss interactions of Se with major toxicant metals (Hg, As, and Cd) frequently present in soil. We highlight key challenges in the quest to improve Se biofortification, with a focus on both agronomic practice and human health.

The migration behaviors of As, Se and Pb in ultra-low-emission coal-fired units were investigated and the effect of co-firing of sewage sludge and coal was explored in circulating fluidized-bed (CFB) boiler units. Samples of feed fuel including coal and sewage sludge, fly ash, bottom slag and desulfurization slurry were collected from five CFB units with a capacity between 150 MW and 350 MW and two pulverized coal boiler (PC) units with a capacity of 350 MW and 600 MW. The majority of As, Se and Pb in coal is released during coal combustion and enriched in fly ash. As, Se and Pb in fly ash and bottom slag are associated with inorganic matter, of which As, Se and Pb associated with silicates and aluminosilicates account for more than 60%. In the wet flue gas desulfurization (WFGD) unit, more than half of the As, Se and Pb migrates to the solid fraction and the concentrations of As, Se and Pb in fine solid particles are much higher than those in coarse solid particles and the liquid fraction. The proportions of exchangeable As, Se and Pb or associated with organic matter in gypsum are higher than those of fly ash and bottom slag. According to the two studied CFB units with blending ratios of sewage sludge below 10%, co-firing with sewage sludge has little effect on the migration and transformation characteristics of As, Se and Pb. Under a long-term acidic leaching environment, Pb in combustion by-products is in the range of low risk, while As and Se are in the range of medium risk.

A large area of soil in China is deficient in selenium (Se) and zinc (Zn)，meanwhile, Se and Zn are essential trace elements for human body, so it is of great significance to find Se and Zn rich soil to cultivate crops. Based on the data of Se and Zn in topsoil, crops and root soil obtained from 1:50000 land quality geochemical survey, this paper taking the western area of Fuling in Chongqing as the research area, studies the content and spatial distribution characteristics of Se and Zn in soil and crops, and analyzes the enrichment law of Se and Zn in agricultural crops. The results show that the average values of Se and Zn in the topsoil of the study area are 0.265mg/kg and 77.56mg/kg respectively. There are some differences in the contents of Se and Zn in different geological backgrounds, soil parent materials and soil types. The high value areas of Se and Zn are mainly distributed in the exposed areas of Triassic carbonate; in the study area, the average contents of Se and Zn in maize seeds are 0.029mg/kg and 20.752mg/kg respectively, and the enrichment rates are 96% and 82% respectively. The average contents of Se and Zn in rice seeds are 0.032mg/kg and 11.463mg/kg respectively, and the enrichment rates are 13.3% and 5% respectively. The bioaccumulation coefficients of Se and Zn in maize are higher than that in rice, and the availability of Se and Zn elements in maize root soil is higher.The results can provide geochemical basis for developing characteristic land resources, functional agriculture and promoting rural revitalization in Fuling District.

The regional environmental changes are affecting groundwater ecosystems in Semarang area. The development of new settlements, industrial complexes, and trade centers have degraded the groundwater setting of the city, which serves as the capital of Central Java Province. This has led us to compile several groundwater quality dataset that have been taken from 1992 to 2007. Our original motivation is to come up with an open dataset that can be used as the baseline for groundwater monitoring. The dataset consists of 58 samples were taken in 1992, 1993, 2003, 2006, and 2007 using well point data from several reports from Ministry of Energy and Mineral Resources, engineering consultants, as well as from researchers from Universitas Diponegoro and Institut Teknologi Bandung. Each site has a set of 20 physical and chemical variables.

Amaç: Bu çalışmanın amacı, Hashimoto tiroiditi (HT) etiyopatogenezinde selenyum (Se) demir (Fe), çinko (Zn) ve bakır (Cu) eser elementlerinin serum düzeylerindeki ve oranlarındaki değişimlerinin belirlenmesi ve bu parametreler arasındaki olası ilişkinin değerlendirilmesidir. Gereç ve Yöntem: Çalışma 35 HT ve 28 sağlıklı birey ile gerçekleştirildi. Çalışmaya dahil edilen tüm bireylere ait serum Se, Zn, Cu ve Fe düzeyleri indüktif eşleşmiş plazma optik emisyon spektrofotometresi (ICP-OES, Thermo iCAP 6000) ile ölçüldü. Bulgular: Serum Se, Fe, Cu ve Zn düzeylerinin HT grubunda kontrol grubuna göre anlamlı derecede azaldığı saptandı (sırasıyla p lt;0,001, p lt;0,001, p lt;0,05 ve p lt;0,001). Cu/Zn ve Cu/Se oranlarının HT grubunda arttığı görüldü. Ayrıca, HT grubunda Cu düzeyleri ile Cu/Zn oranı; Fe/Se ile Cu/Se oranları; Fe/Zn ile Fe/Se oranları; Fe düzeyleri ile Fe/Se ve Fe/Zn oranları arasında pozitif korelasyon olduğu belirlendi. Se düzeylerinin Cu/Se ve Fe/Se oranları ile negatif korelasyon gösterdi. Zn düzeyleri de Cu/Zn oranı ile negatif korelasyon göstermiştir. Sonuç: Çalışmamızın sonuçları, eser element düzeyleri ve oranlarının HT etiyopatogenezinde yer aldığını göstermektedir. Hastalığın altta yatan mekanizmaları ile eser element ve oranlarının etkileşiminin aydınlatılması için daha ileri çalışmalara ihtiyaç duyulmaktadır.

Abstract Background Staphylococcus aureus (S. aureus) internalization into bovine mammary epithelial cells (bMECs) is considered an important pathogenic mechanism for the establishment of mastitis. Given the interesting link between selenium (Se) status and mastitis, our objective was to prove that Se was essential to suppress pro-inflammatory mediators, in part, by modulation of Toll-like receptor2 (TLR2), nuclear factor kappaB (NF-κB) and mitogen activated protein kinase (MAPK) signal transduction pathway in bMECs. Results Results showed that Se (0~ 16 μM) did not affect the growth of bMECs. The mRNA expression of TLR2, Myeloid differentiation factor 88 (Myd88), Interleukin-1 receptor-associated kinase4 (Irak4), Interleukin-1 receptor-associated kinase1 (Irak1) and TNF receptor-associated factor6 (Traf6) in TLR2 signal pathway were increased or significantly increased by S. aureus. Se played an important role in regulating the genes expression of TLR2, Myd88, Traf6 but not in controlling the expression of Irak4 and Irak1. In addition, Se exerted strong inhibitory effects on the genes expression of tumor necrosis factor-alpha (TNF-α), interleukin-1β (IL-1β) and interleukin-6 (IL-6) induced by S. aureus. To further investigate the possible signaling mechanisms involved in the processes, we analyzed the role of MAPK and NF-κB signaling pathway in inflammation response in S. aureus-stimulated bMECs in vitro. Results showed that the phosphorylation of inhibitory kappaB alpha (IκBα), p65, p38 and extracellular regulated protein kinase (Erk) were significantly increased in S. aureus-stimulated bMECs. It indicated that S. aureus activated NF-κB and MAPK signaling pathway. We also examined the effects of Se on the phosphorylation of IκBα, p65, p38 and Erk in NF-κB and MAPK signaling pathway, which have well been proved to control the synthesis and release of pro-inflammatory mediators during inflammation. The findings are exciting, that pretreatment with Se (4, 8 μM) significantly suppressed the phosphorylation of IκBα, p65, p38 and Erk. Conclusions These results suggest that Se down-regulates inflammatory mediators TNF-α, IL-1β and IL-6 gene expressions via TLR2, NF-κB and MAPK signaling pathway in S. aureus-stimulated bMECs, which may be responsible for the anti-inflammatory effect of Se.

An ecological and biological examination of adolescents of the following ethnic groups of Khabarovsk Krai was conducted: Nivkhs (n = 25), Evens (n = 54) and newly arrived Russians (n = 23), whose average age amounted to 14.57 ± 0.24, 14.6 ± 0.2 and 15.00 ± 0.32, respectively. Fe, Cu, Mo, Zn, Co, Se, Th, U content in samples of blood serum and hair was determined by atomic emission spectroscopy with inductively-coupled plasma. The elemental analysis of the diet was performed by means of questionnaires, and with the help of «Correct Food 6.5» software based on the reference book «Chemical composition of foods» (edited by Academician of the Academy of Medical Sciences A.A. Pokrovsky). Analysis of biosubstrates revealed elemental imbalance in all ethnic groups. The high concentrations of Th and U in the blood serum and hair of adolescents was an additional factor of inversion of elemental homeostasis.

Objective. To clarify the association between HLA-DRB1 and TNFα (-308G>A) genes polymorphism and joint destruction/further progression during 12 months of the follow-up period (FUP) in patients with early (

Massive multiple-input multiple-output (MIMO) is envisioned to meet the growing spectral efficiency (SE) requirement in next generation cellular systems. However, it has been recognized that the unaffordable channel state information reference signal (CSI-RS) overhead required for acquiring CSI is a major challenge in frequency division duplexing (FDD) massive MIMO systems. To tackle the challenge of this CSI-RS overhead limitation, certain attempts, which have been designed for the scenarios with dispersive locations of users and sparse nature of channels, suffer from inaccurate channel estimation when the nature of channels for different users becomes highly correlated and rich. In this paper, we propose an enhanced CSI acquisition scheme for FDD multi-user massive MIMO systems, which exploits beamformed CSI-RS transmission mechanism to reduce the CSI-RS overhead. We present two limited feedback algorithms which provide different tradeoffs between system performance and CSI feedback overhead, where the multistage CSI acquisition strategy is adopted to avoid prohibitive computational complexity and amount of feedback requirement. The simulation results show that our CSI acquisition scheme, without additional CSI-RS overhead and enormous CSI feedback overhead, achieves higher SE performance as compared to conventional scheme.

This study was conducted to determine the effect of dietary supplementation of organic zinc (Availa®Zn100) and selenium (Availa®Se1000) on semen characteristics, testes measures and serum testosterone concentration. Twenty Sanjabi rams (50.01 ± 5.6 kg) were randomly divided into four equal groups, given the basal diet as control (C) or supplemented with 0.3 mg/kg Se (SE) or 40 mg/kg Zn (ZN) or 40 mg/kg Zn plus 0.3 mg/kg Se (ZS) for 120 days experiment (from July to November). The semen samples and blood samples were collected every 3 weeks and scrotal circumference was measured every 15 days. The results indicated that scrotal circumference and testosterone concentrations did not differ due to treatment (P > .05). In contrast, semen characteristics were affected by ZS supplementation. The sperm density and total sperm number increased (P

Selenium (Se) is an essential element for humans and animals and its deficiency in the diet is a global problem. Crop plants are the main source of Se for consumers. Therefore, there is much interest in understanding the factors that govern the accumulation and distribution of Se in the tissues of crop plants and the mechanisms of interaction of Se absorption and accumulation with other elements, especially with a view toward optimizing Se biofortification. An ideal crop for human consumption is rich in essential nutrient elements such as Se, while showing reduced accumulation of toxic elements in its edible parts. This review focuses on (a) summarizing the nutritional functions of Se and the current understanding of Se uptake by plant roots, translocation of Se from roots to shoots, and accumulation of Se in grains; and (b) discussing the influence of nitrogen (N), phosphorus (P), and sulfur (S) on the biofortification of Se. In addition, we discuss interactions of Se with major toxicant metals (Hg, As, and Cd) frequently present in soil. We highlight key challenges in the quest to improve Se biofortification, with a focus on both agronomic practice and human health. [ABSTRACT FROM AUTHOR]

Most native speakers of Spanish are intuitively able to construct correct structures with the marker 'se'. On the other hand, non-native speakers, even those at advanced proficiency levels, have difficulties producing most constructions with 'se'. This is hardly surprising as the marker 'se', one of the most common words in Spanish, can convey highly pragmatic nuances with a variety of functions that are still much debated among linguists. This study analyses some of the most used functions of the marker in the oral production of 18 Peninsular Spanish speakers from a multimodal Cognitive Grammar approach, identifying how gestures might be employed by speakers to create or clarify meaning. Our results confirm that gestures are used differently depending on the function of the marker. Middle voices where 'se' marks high levels of subject involvement and/or energy co-occur with related gestures, while middle voices or impersonal structures, where the involvement and/or energy is low, co-occur more often with unrelated gestures, if any. [ABSTRACT FROM AUTHOR]

Studies conducted in various countries, including Bulgaria, prove the antimicrobial/antiviral action of Salvia officinalis in a number of pathogens, including SARS-CoV coronaviruses. The effect is due to its biologically active substances. The medicinal plant has a history of millennial application in the field of pulmonology and is used today in medicines for respiratory diseases. During the March-June 2020 period, a positive effect was observed in the treatment of viral diseases, including COVID-19 at home in about 20 patients* with two preparations containing Salvia officinalis and other medicinal plants - Immuno Pam Plus with antiviral effect, as well as Broncho Pam with application in pulmonology. Zn (Zinc) and Se (Selenium) were included in the therapies, combined with antipyretic drugs containing paracetamol and acetylsalicylic acid with preventive effect against blood clots. This article presents a detailed description of 4 typical clinical cases with different manifestations, ranging from mild symptoms to pneumonia in a patient with COPD and analyzes the therapeutic methods taken and their results. In the latter case antibiotics were added. [ABSTRACT FROM AUTHOR]

Référence: Schepers N, Hallensleben N, Besselink M, et al., on behalf of the Dutch Pancreatitis Study Group. Urgent endoscopic retrograde cholangiopancreatography with sphincterotomy versus conservative treatment in predicted severe acute gallstone pancreatitis (APEC): a multicentre randomised controlled trial. Lancet 2020 ; 396 : 167-176. [ABSTRACT FROM AUTHOR]

Status epilepticus (SE) is a neurological disorder associated with high morbidity and mortality rates, and is often difficult to treat. Moreover, the underlying mechanism of SE remains unknown. The lithium-pilocarpine model is a validated animal model that can reproduce the main clinical and neuropathological features of SE. In the present study, this SE model was utilized and SE was successfully established in rats, as determined by the corresponding epileptic electroencephalogram. Histology, immunohistochemistry, western blot analysis and co-immunoprecipitation were used to detect the phosphorylation (p-) of AKT substrate of 40 kDa (PRAS40), the combination of p-PRAS40 and 14-3-3 protein and the activation of the PI3K/mTOR signaling pathway in SE. In addition, the present study analyzed the dynamics of the expression of autophagy-associated factors in the hippocampus after SE induction, and the influence of suppressing the p- of PRAS40 on the autophagy process was detected in the pathogenesis of SE. The results indicated that increased p-PRAS40 expression could activate the mTOR pathway to decrease the level of autophagy. However, inhibition of the mTOR signaling pathway promoted autophagy flux. These results may provide further understanding of p-PRAS40 functions in SE. [ABSTRACT FROM AUTHOR]

Background: Colorectal cancer (CRC) is considered the fourth type of cancer that causes death worldwide. Changes in the levels of zinc (Zn), copper (Cu), and selenium (Se) as well as low glutathione peroxidase (GPx) activity can lead to CRC and this study was aimed to evaluate their possible use as diagnostic markers. Methods: CRC patients (n=90) were divided into three groups; newly diagnosed, before surgery, and after surgery. These groups were compared to healthy subjects (n=30); the mean age ±SD was 50.63±9.26 and 49.97±10.85 for CRC patients and healthy subjects, respectively. Biochemical study for serum levels of Zn and Cu was measured by FAAS, Se was measured by HGAAS, and ELISA for GPx. Results: Zn, Cu, Se and GPx were significantly lower in all CRC patient groups, except for the after surgery group which showed no differences for Zn and GPx as compared to the healthy subjects. Positive correlations were found between Se and Zn and between Se and GPx (r=0.71, r=0.42; P<0.01, respectively) in all CRC patient groups. A receiver operating characteristic (ROC) curve analysis was applied for the newly diagnostic group showing all the parameters that can be used as diagnostic markers for CRC. Conclusion: The present results conclude that Zn, Cu Se, and GPx can be used as diagnostic markers for CRC, where the decrease of these parameters may be associated with an increased risk of CRC and as indicators of the response to therapy. [ABSTRACT FROM AUTHOR]

Introduction: Pregnancy specific complication characterised by hypertension, proteinuria, after 20 weeks of the gestation, and along with various signs of damage to organ systems, haemolysis, elevated levels of liver enzymes and low platelet count (HELLP syndrome) is collectively termed as eclampsia. Method: Cross-sectional study with 3 groups of pregnant women, were taken followed by inclusion and exclusion criteria for characterisation. The study was approved by ethical board of DMIMSU. Minerals and their relationship were estimated using different method. Preeclamptic group with and without supplementation and pregnant women without preeclampsia were included in the study. Significant differences were seen in Na+, K+, Ca, Mg, Se, and Mn when compared with each group. Result and Observation: The levels of K were increased significantly (P < 0.001) in pre-eclamptic group as compared to control group. There was significant change in levels of Mn when pre-eclamptic group was compared to control. Mn was also found to decrease significantly (P < 0.001) in cases as compared to control. However, the levels of Se, Mg, Ca and Na between cases and control were not highly significant. In supplementation and without supplementation group, Significant differences were seen in levels of Na, K, Ca and very significant difference was seen in levels of Mn. (p<0.0001). Conclusion: Pre-eclamptic pregnant women have higher levels of serum potassium and our finding on Mn, an essential trace mineral, provides new insight into a potentially modifiable way to prevent preeclampsia. In multi-ethnic, predominantly urban and low-income pregnant women high level of Mn is associated with pre-eclampsia. [ABSTRACT FROM AUTHOR]

Rock breaking using conical picks is a complex process affected by several factors; its performance is directly related to the excavation rate of rock tunnels, which is important in terms of the economic benefits and social impact of a project. This study investigates the effects of cutting depth and water pressure on rock breaking performance using a conical pick assisted by an abrasive water jet (AWJ). To measure the weakening effect of the AWJ on rock strength and evaluate the practical application of this approach, further analyses of a secondary cut of rock with a fracture pit and rock breaking economy are included in this study. The results show that a conical pick can efficiently break hard rock when assisted by the strong impact of an AWJ; the cutting resistance and specific energy (SE) decrease with the use of the AWJ. With a fracture pit and surrounding tiny cracks, the cutting resistance during the secondary cut is further reduced and rock fragments become smaller. In addition, with a decrease in cutting depth and an increase in water pressure, the stability of the cutting resistance is improved, reducing conical pick costs resulting from impact fracture and wear. According to the rock breaking economy analysis of the proposed approach, there is an optimal cutting depth under certain conditions that can provide a reference for practical application. [ABSTRACT FROM AUTHOR]

Molybdenum carbide (β-Mo 2 C) possesses excellent electrical conductivity, good thermal and chemical stability, and is, therefore, a promising candidate material for electromagnetic (EM) shielding in diverse harsh environments. Herein, for the first time, β-Mo 2 C based ultra-thin films were prepared through in-situ growth of the carbide on a self-assembled graphene oxide (GO) film. The remaining reduced GO (RGO) layers located in between two adjacent Mo 2 C nanoparticles not only can work as flexible binder to impart the resultant films excellent flexibility but also enable the formation of heterogeneous nano-interface which is beneficial for the improvement of shielding by absorption. The amounts of β-Mo 2 C in the resultant films were adjusted through varying the Mo precursor contents. With the introduction of β-Mo 2 C phase in the resultant film, the shielding effectiveness (SE) increased significantly. At the thickness of ∼25 μm, the highest SE reaches 46.8 dB compared to 21.6 dB of the pristine RGO film. With the increase of the Mo 2 C content in the resultant materials, the density increased from 0.32 to 1.23 g/cm3. The resultant Mo 2 C film exhibit an SSE/t (specific SE by thickness) value of as high as 15,971 dB cm2 g−1. Image 1 [ABSTRACT FROM AUTHOR]

This study evaluated the optimal concentrations of dietary Se for the productive and reproductive performance, tibial quality, and antioxidant status in duck breeders aged 23 to 49 wk. In total, 432 Longyan duck breeders aged 22 wk were allotted randomly to 6 treatments, each with 6 replicates of 12 individually caged birds. The experiment lasted for 27 wk, and birds were fed corn-soybean meal-based diets containing 0.11, 0.19, 0.27, 0.35, 0.43, or 0.51 mg Se/kg, respectively. The tested dietary Se levels did not affect egg production and tibial quality of duck breeders. The Se contents of the shell, yolk or albumin, whole egg, and the fertility of set eggs increased in a linear and quadratic manner (P < 0.05) in response to the increased dietary Se level, whereas the yolk malondialdehyde (MDA) and embryonic mortality decreased. The activities of glutathione peroxidase 3 (Gpx3) in plasma and Gpx1 in the erythrocytes and livers of breeder ducks increased in a linear and quadratic manner (P < 0.05) in response to increased dietary Se levels, whereas the total superoxide dismutase (T-SOD) activity increased and the MDA concentration decreased in the liver. The activity of Gpx3 in the plasma and Gpx1 in the erythrocytes and livers of newly hatched ducklings increased linearly (P < 0.01) with the increase in Se level, whereas the T-SOD activity and MDA concentration did not change. In conclusion, diets containing 0.27 mg Se/kg led to the highest egg fertility and hatchability in Longyan duck breeders, and using levels >0.19 mg Se/kg diet enhanced the antioxidant capacity in breeders and their offspring. The regression model indicated that dietary Se levels 0.19, 0.27, 0.28, 0.24, and 0.30 mg/kg are optimal levels to obtain maximum Se deposition efficiency in eggs, egg fertility, Gpx1 activity in erythrocytes and liver in duck breeders, and plasma activity of Gpx3 in newly hatched ducklings, respectively. [ABSTRACT FROM AUTHOR]

Aiming at the problems of severe vibration of switched reluctance motor (SRM) and the transfer of the peak vibration caused by newly produced radial magnetic force under static eccentricity (SE), this study proposes a vibration reduction method for SE. First, the analytical relationship between the radial magnetic force harmonics and the current harmonics is derived. 2D Fourier decomposition is used to analyse the temporal–spatial characteristics of force harmonics and the vibration response under SE. Then the expression of the force harmonic, which causes the peak vibration, is used as the optimisation function of current harmonics. According to the analyses in this study, it is difficult to consider vibration reduction and torque simultaneously by single‐order current harmonic optimisation and the unreasonable optimisation range of current will seriously affect the output performance. Therefore, a reasonable optimisation range is set based on the above conclusions and the first five order current harmonics are optimised to improve the effect of vibration suppression further. The results of the finite element simulation verify the effectiveness of this method. [ABSTRACT FROM AUTHOR]

In this work, novel flower‐like nanoscale zero‐valent iron/zinc oxide heterostructure composites were prepared, characterised and used for the enhanced removal of Se(IV) from water. The morphological identification showed that nZVI nanoparticles were uniformly loaded on ZnO nanosheets to minimise their aggregation. Batch experimental results demonstrated that the composites exhibited higher removal efficiency and rate constant on Se(IV) immobilisation than pristine flower‐like ZnO and nZVI because of the enhanced dispersion of nZVI nanoparticles. Solution pH, initial Se(IV) concentration as well as interfering ions that affect the removal capacity of Se(IV) were further studied. These results suggested that the composites could be a promising candidate for the potential application in effective remediation of Se‐contaminated wastewater. [ABSTRACT FROM AUTHOR]

The concept of self is becoming more and more a topic of interest in neuroscience. Several authors have been elucidating the neural correlates of the self and assume that the self may play a central role in the neural architecture of the brain (Panksepp, 1998; Northoff and Bermpohl, 2004; Northoff and Panksepp, 2008), for example, comparing self- and non-self specific stimuli, they found major changes in the Cortical Midline Structure (SCMS) and Sub-Cortical Midline Structure (SCMS). The concept of self seems to constitute a predisposition for individual differences in behavior, cognitions, emotions etc., i.e., one's personological profile. The notion that interpersonal relatedness and self-definition issues are central in personality disturbances and in the development of personality has been strongly influenced by attachment theory (Fonagy & Luyten, 2009; Fonagy et al., 2010; Levy, 2005) and contemporary interpersonal formulations (Pincus, 2005). Theory and research in this field have addressed the role of early caregiving relationships in the development of representations of self and others in both, normal and disrupted development (Blatt, Auerbach and Levy, 1997). This conceptualization is very much coherent with several psychoanalytic formulations that point out how relatively satisfactory caring experiences are potentially facilitating the development of a differentiated and cohesive sense of self and a capacity for increasingly mature interpersonal relatedness and capacity for intimacy (Blatt & Blass, 1996; Kernberg, 1975; Kohut, 1971). Intersubjectivity and the concept of Self seem to be closely related to each other. Other individuals are approached as similar to the self, i.e. with similar mental and bodily experiences (feelings, sensations), different from the inanimate world. We are moving towards a new model that can develop a bridge between Neuroscience, Psychoanalytic formulations and Clinical practice. The neuroscientific relational-constructional concept of the Self and the study of the Resting State Activity in relation to Laboratory tasks can shed a light on the importance of intersubjectivity and intentional attunement (Gallese, Eagle, Migone, 2007) between individuals. We aim to propose our empirical findings on the relation between resting state activity and a laboratory task based on touch (intention to touch a human animate hand vs. a mannequin inanimate hand), given that touch has a privileged status in making possible the social attribution of lived personhood to others. Our results suggest how our brain during resting state seems to be relational by default, it encodes selfawareness necessary to relate with others individuals but not with inanimate objects. Will be discussed how neuroscientific findings have an impact on psychoanalytic concepts releted to clinical practice and how both, the study of Resting State Activity and Task Evoked Activity of the brain can be related to concepts like intentional attunement, empathy and how interaction between different state of the brain/mind can inform clinical practice on Self-Other representations. [ABSTRACT FROM AUTHOR]

The revolution of 1968 represented, for Western culture, the beginning of a radical and continuous change. This process affected all areas of life and, among them, the way to experience the affective and sexual dimension. The way in which the contemporary man and woman - and young people in particular - build the relationship with their own and with the body of others has changed, applying to the affective and sexual sphere, the same dynamics that the postmodernity ascribes to the relational field in a broader sense. With the perspective point of view reduced, the design dimension seems to be very limited, in favour of a radical anchorage to the present, but not in the perspective of the depth of experience. This approach to self, to the other and to life in general, while generating a sense of apparent power, places the subject in a state of disorientation, for which the need to reformulate, according to new languages, new answers to existential questions that, continuously, recur to experiencence, is urgent. [ABSTRACT FROM AUTHOR]

In order to study the effect ofSS(squalene synthase) and SE (squalene epoxidase) genes co-over-expression in hairy roots of Panax japonicus on ginsenoside Resynthesis, the callus of P· japonicus was used as receptor material. The double expression vector of SS and SE genes were constructed respectively and transformed the P· japonicus callus by Agrobacterium LBA4404. Finally, C58Cl was used to induce hairy roots from Callus of transgenic P· japonicus. The results of PCR showed that SS and SE genes could be integrated into hairy roots of P· japonicus individually or jointly. RP-HPLC indicated that Re content in transgenic P·japonicus hairy roots was 2.4 times and 2.3 times of that in non-transgenic ones (CK) when SS and SE geneswere transferred alone. The Re content in transgenic P· japonicus hairy roots was 5.3 times that of the non-transgenic ones when SS and SE genes co-over-expression. It can be seen that the SS and SE genes has a positive regulatory effect on Re synthesis in P· japonicus hairy roots and the co-over-expression of SS and SE genes canincrease Re content. [ABSTRACT FROM AUTHOR]

This is the second part of an article that tries to provide a framework of understanding of, and a seminal reflection on, a highly interesting yet little explored psychological construct of Jung's analytical psychology, namely the 'mana personality'. Here I take into consideration some issues around the 'saviour complex', discussed in Jung's seminar on Nietzsche's Zarathustra, concerning both the psychological analysis of the individual and the socio-political level related to the collective horizon of the 1930s. Moreover, I consider the continuity of Jung's analysis of such issues in other works such as 'Psychology and national problems' (1936), Symbols of Transformation (1952), and Aion (1950). I finally make some suggestions concerning Jung's apparent hermeneutic tendency to apply the construct of the mana personality to collective historical phenomena. [ABSTRACT FROM AUTHOR]

Copyright of Chinese Journal of Inorganic Analytical Chemistry / Zhongguo Wuji Fenxi Huaxue is the property of Beijing Research Institute of Mining & Metallurgy Technology Group and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Aufklärung: Revista de Filosofia is the property of Aufklarung: Revista de Filosofia and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

According to Jung, the 'mana personality' represents an archetypal phase of the individuation process of remarkable interest in psychological, hermeneutic and theoretical terms. This figure is characterized by a high initiatic potential that fosters the approximation of the consciousness of the Self. At the same time, it entails a risk of psychic inflation or of 'similarity to God'. In this article, divided in two parts, I deal with those aspects through a reconstruction of the development of this notion within Jung's published works, adopting a primarily chronological and, secondarily, thematic approach moving from a textual analysis of relevant passages. In this first part, I consider some passages which deal mainly with the risks of the assimilation of the unconscious in 'La structure de l'inconscient' (1916) that preceded the successive proper treatment of the mana personality's notion presented, and here examined, in 'The relations between the ego and the unconscious' (1928). Successively, I take into consideration some further issues related to it discussed by Jung in 'The structure of the psyche' (1928/1931), 'Archaic man' (1931), and 'Nietzsche's Zarathustra'. [ABSTRACT FROM AUTHOR]

This paper investigates the relations between displacement, home, trauma and the self in the experience of refugees, which has become an issue of unexpected and far-reaching proportions in recent times. It questions to what extent and under what conditions displacement in the world may be traumatic and how trauma may be considered the effect of an inner displacement. Refugees' lives are marked by forced migration that is related to a certain suffering due to the changes in their family, relational, social and cultural lives. The paper explores the extent to which these changes can represent a break so significant as to be traumatic. It outlines the way in which traumatic experiences can produce an inner displacement and reorganization of one's mental life that leads to a focus on traumatic complexes. Under the most severe traumatic conditions, this can be understood as a displacement of the central axis of Self, in which the ego complex yields its position to other complexes, with a deep change in the organization and functioning of self. The experience of refugees highlights the way in which we live in a matrix of conscious and unconscious links between inner and outer worlds that need deeper and simultaneous consideration to understand their implications and mutual resonances for the psyche. Clinical cases of refugees will illustrate some aspects of these interconnections. [ABSTRACT FROM AUTHOR]