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3,367 results on '"Miyazaki, H."'

201. Effect of TiC and NbC carbides on creep life of stainless steels.

Author

Abe, F., Murata, M., and Miyazaki, H.

Subjects
CARBIDES, AUSTENITIC stainless steel, CREEP (Materials), PRECIPITATION hardening, TITANIUM carbide, OSTWALD ripening
Abstract

The effect of TiC and NbC carbides on creep life has been investigated for 321HTB and 347HTB steels at 600-750°C for about 20-200,000 h. The creep data for 304HTB steel are used as reference data. The precipitation hardening is larger for the 321HTB than for the 347HTB at short times during creep. Then the reduction of precipitation hardening due to coarsening of TiC and NbC carbides takes place for up to long times, which is less significant in the 321HTB than in the 347HTB. The smaller coarsening rate of the TiC carbides than the NbC carbides during creep is discussed on the base of a rate equation for diffusion-controlled Ostwald ripening. [ABSTRACT FROM AUTHOR]

Published
2019
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204. Urban Observing Sensors

Author

Weng, Q., Gamba, P., Mountrakis, G., Pesaresi, M., Lu, L., Kemper, Thomas, Heinzel, J., Xian, G., Jin, H., Miyazaki, H., Xu, B., Quresh, S., Keramitsoglou, Iphigenia, Ban, Y, Esch, Thomas, and Elvidge, C.D.

Subjects
Sensors, Urban
Published
2014

213. Longitudinal relationship of severe periodontitis with cognitive decline in older Japanese

Author

Iwasaki, M., primary, Yoshihara, A., additional, Kimura, Y., additional, Sato, M., additional, Wada, T., additional, Sakamoto, R., additional, Ishimoto, Y., additional, Fukutomi, E., additional, Chen, W., additional, Imai, H., additional, Fujisawa, M., additional, Okumiya, K., additional, Taylor, G. W., additional, Ansai, T., additional, Miyazaki, H., additional, and Matsubayashi, K., additional

Published
2016
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214. On the Thickness of Sacrificial Steel Wall for Protection of Sea Ice Action.

Author

Takeuchi, T., Kioka, S., and Miyazaki, H.

Abstract

Damage has been reported to coastal structures and training levees made of steel sheetpile-type seawalls in the sea of Okhotsk facing Hokkaido, Japan. This damage has been caused by various effects such as wear, abrasion, and deformation of steel sheet piles resulting from the action of sea ice. If rust layers due to corrosion of steel surfaces are removed by the action of sea ice in the wintertime, the corrosion amount will increase further during ice-free periods due to activation of these surfaces. Consequently, this process of corrosive wear leads to larger wear of steel structures in ice-infested sea than that in ice-free sea. We consider sacrificial steel walls with/without concrete lining in addition to the base steel structure as a useful countermeasure to sea ice action. A method for estimating the required thickness of a sacrificial steel wall is proposed. From a sliding wear test in a cold room, it is also shown that the effect of sand inclusion in sea ice on the wear rate of steel in the mild (steady) wear region is crucial. [ABSTRACT FROM AUTHOR]

Published
2017

220. Lysis of autologous tumor cells by large granular lymphocytes in patients with acute leukemia in complete remission: Correlation between lytic activity and clinical outcome

Author

Miyazaki H, Masataka Okamoto, Matsui T, Masami Hirano, Kojima H, Maruyama F, Ezaki K, Wakita M, Nomura T, Ino T, and Motohiro Tsuzuki

Subjects
Adult, Male, Cancer Research, Cellular immunity, medicine.medical_specialty, Adolescent, Lymphocyte, Gastroenterology, Myelogenous, Recurrence, Acute lymphocytic leukemia, Internal medicine, Humans, Medicine, Cytotoxic T cell, Lymphocytes, Child, Aged, Retrospective Studies, Acute leukemia, business.industry, Remission Induction, Hematology, Middle Aged, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Prognosis, medicine.disease, Leukemia, Myeloid, Acute, Leukemia, medicine.anatomical_structure, Oncology, Immunology, Female, business, K562 cells
Abstract

In order to evaluate the effect of specific immune response on prognosis in acute leukemia, we investigated the correlation between the lysis of autologous tumor cells (ATC) by lymphocytes and prognosis. Peripheral mononuclear cells (PMC) from most patients with acute leukemia in complete remission (CR) do not exhibit cytotoxic activity against fresh-frozen ATC, although they have adequate cytotoxic activity against K562 cells. When the large granular lymphocyte (LGL) fraction was used in this study, we observed lysis of ATC in 17 (43.6%) of 39 patients with acute leukemia (12 (42.9%) of the 28 patients with acute myelogenous leukemia (AML) and 5 (45.5%) of the 11 patients with acute lymphocytic leukemia (ALL)). With regard to prognosis, the lytic activity of the LGL fraction did not reflect the duration of CR. The median CR duration in AML patients was 13 months for the lysis-positive group and 11 months for the lysis-negative group. No significant correlation was also found between lytic activity of the LGL fraction and overall survival in each patient. However, the lysis-positive group tended to have a longer survival, the median overall survival being 48 months for the lysis-positive group vs 12 months for the lysis-negative group. The prolonging of overall survival in the lysis-positive group was attributed to a high rate of induction of second remissions in this group. Long-term patient survival in the two groups did not differ.

Published
1994

238. Intensive sequential post-induction therapy for adults with acute myelogenous leukemia in first remission: Long-term follow-up and results

Author

Sobue R, Maruyama F, Masataka Okamoto, Matsui T, Miyazaki H, Kazuyuki Shimizu, Kojima H, Ino T, Ezaki K, and Masami Hirano

Subjects
Adult, Male, Cancer Research, medicine.medical_specialty, Adolescent, Long term follow up, Prednisolone, medicine.medical_treatment, Myelogenous, Induction therapy, Antineoplastic Combined Chemotherapy Protocols, medicine, Humans, Life Tables, Aclarubicin, Aged, Etoposide, Chemotherapy, Mercaptopurine, business.industry, Daunorubicin, Remission Induction, Cytarabine, First remission, Hematology, Middle Aged, medicine.disease, Confidence interval, Surgery, Survival Rate, Leukemia, Myeloid, Acute, Leukemia, Oncology, Toxicity, Female, Mitoxantrone, business, Follow-Up Studies
Abstract

We designed a post-induction therapy including intensive sequential therapy with non-cross-resistant drugs in an effort to prolong disease-free survival (DFS) for adults with acute myelogenous leukemia. Forty-five patients entered this study and 33 of 35 patients entering complete remission received the post-induction therapy. With a median follow-up for survivors of 3.5 years from complete remission, the actuarial 5-year DFS was 46% ± 19% (95% confidence interval). The five-year DFS for patients over 45 years of age was comparable to that for patients under 45 years of age (50% ± 26% vs 47% ± 28%). Furthermore, the actuarial 5-year DFS for patients who required two courses of induction therapy was comparable to that for patients who required only one course of induction therapy (45% ± 29% vs 50% ± 25%). The toxicity of post-induction therapy was tolerable and no patients died during complete remission.

Published
1992

239. Alternating non-cross-resistant chemotherapy for non-Hodgkin's lymphoma of intermediate-grade and high-grade malignancy. A pilot study

Author

Wakita M, Miyazaki H, Masatni Hirano, Ino T, Kazuyuki Shimizu, Maruyama F, Nomura T, Kouichi Shinkai, Ezaki K, Masataka Okamoto, Matsui T, and Sobue R

Subjects
Cancer Research, Vincristine, medicine.medical_specialty, Chemotherapy, Ifosfamide, Cyclophosphamide, business.industry, medicine.medical_treatment, Bleomycin, medicine.disease, Gastroenterology, Surgery, Non-Hodgkin's lymphoma, chemistry.chemical_compound, Oncology, chemistry, Internal medicine, medicine, Prednisolone, business, Etoposide, medicine.drug
Abstract

Thirty-two patients with advanced non-Hodgkin's lymphoma (NHL) with aggressive histologic findings were treated with cyclophosphamide, doxorubicin, methotrexate with leucovorin rescue, bleomycin, vincristine, etoposide, ifosfamide, and prednisolone (CAMBO-VIP), in which presumably non-cross-resistant myelosuppressive and nonmyelosuppressive agents were administered during alternate weeks for 12 weeks. To ensure the high-dose intensity of the protocol, dose reduction and delay in treatment were minimized. Three patients were treated inadequately. Twenty-six (89.7%) of 29 evaluable patients had a complete response, and three had a good partial response. Relapse occurred in four patients, with a median follow-up of 29 months. The actuarial overall survival and disease-free survival were estimated to be 87.6% and 75.9%, respectively. The CAMBO-VIP treatment was well tolerated; myelosuppression was severe but transient and caused no serious infections. Side effects that affected dose intensity were oral ulceration, occurring in 28 patients, and blister formation under the thickened skin of palms and/or soles, followed by desquamation (5 patients). Hepatic toxicity was generally mild to moderate; it was severe in one patient. A 12-week regimen of CAMBO-VIP was effective for advanced NHL with aggressive histologic findings.

Published
1992

245. In-situ straining and time-resolved electron tomography data acquisition in a transmission electron microscope.

Author

Hata, S., Miyazaki, S., Gondo, T., Kawamoto, K., Horii, N., Sato, K., Furukawa, H., Kudo, H., Miyazaki, H., and Murayama, M.

Subjects
MATERIAL plasticity, TRANSMISSION electron microscopes, DATA acquisition systems, DATA visualization, DEFORMATION of surfaces
Abstract

This paper reports the preliminary results of a new in-situ three-dimensional (3D) imaging system for observing plastic deformation behavior in a transmission electron microscope (TEM) as a directly relevant development of the recently reported straining-and-tomography holder [Sato K et al. (2015) Development of a novel straining holder for transmission electron microscopy compatible with single tilt-axis electron tomography. Microsc. 64: 369-375]. We designed an integrated system using the holder and newly developed straining and image-acquisition software and then developed an experimental procedure for in-situ straining and time-resolved electron tomography (ET) data acquisition. The software for image acquisition and 3D visualization was developed based on the commercially available ET software TEMographyTM. We achieved time-resolved 3D visualization of nanometer-scale plastic deformation behavior in a Pb-Sn alloy sample, thus demonstrating the capability of this system for potential applications in materials science. [ABSTRACT FROM AUTHOR]

Published
2017
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249. Development of potent non-peptide GPIIb/IIIa antagonists with tri-substituted β-amino acid derivatives as a new conformational restriction unit

Author

Hayashi, Y., primary, Katada, J., additional, Harada, T., additional, Iijima, K., additional, Tachiki, A., additional, Takiguchi, Y., additional, Muramatsu, M., additional, Miyazaki, H., additional, Asari, T., additional, Okazaki, T., additional, Sato, Y., additional, Yasuda, E., additional, Yano, M., additional, Ojima, I., additional, and Uno, I., additional

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