7,927 results on '"M. Berger"'
Search Results
202. 2. Commercial Hard Rock in Cleveland, Ohio: Dia Pason and Max Panic
- Author
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Harris M. Berger
- Published
- 1999
203. Part One. The Ethnography of Musical Practice
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Harris M. Berger
- Published
- 1999
204. 1. An Introduction to Central Issues in Ethnomusicology and Folklore: Phenomenology and Practice Theory
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Harris M. Berger
- Published
- 1999
205. 4. Two Jazz Scenes in Northeast Ohio
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Harris M. Berger
- Published
- 1999
206. Acknowledgments
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Harris M. Berger
- Published
- 1999
207. Contents
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Harris M. Berger
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- 1999
208. List of Illustrations
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Harris M. Berger
- Published
- 1999
209. Foster Care, Permanency, and Risk of Prison Entry
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Sarah A. Font, Maria Cancian, Jessie Slepicka, and Lawrence M. Berger
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Gerontology ,Race ethnicity ,Emancipation ,Social Psychology ,media_common.quotation_subject ,050901 criminology ,05 social sciences ,Prison ,Article ,Foster care ,Legal guardian ,0501 psychology and cognitive sciences ,Sociology ,0509 other social sciences ,050104 developmental & child psychology ,media_common - Abstract
Objective: (1) Examine associations of foster care exit type (e.g., reunification with birth family, adoption, guardianship/permanent relative placement, or emancipation from care) with risk of entry into state prison; (2) Examine racial disparities in those associations. Method: With data on over 10,000 Wisconsin youth who entered foster care in mid- to late-childhood, we present imprisonment rates in young adulthood by race, sex, and foster care exit type. Proportional hazards models with a robust set of covariates compared prison entry rates among the most common exit types—reunification, aging out, and guardianship/permanent relative placement. Results: Nearly 13 percent of the sample experienced imprisonment in young adulthood. Compared with emancipated youth, hazard of imprisonment was 1.58–1.96 times higher among reunified youth. Differences were largely unexplained by observed individual, family, or foster care characteristics. Imprisonment rates were similar for emancipated youth and youth exiting to guardianship/permanent relative placement. Hazard of imprisonment for reunified Black youth was twice that of reunified white youth, but racial differences in prison entry were statistically non-significant among emancipated youth. Conclusion: Efforts to reduce incarceration risk for all youth in foster care are needed. Reunified youth may benefit from services and supports currently provided primarily to emancipated youth.
- Published
- 2021
210. Swiss neonatal caregivers express diverging views on parental involvement in shared decision‐making for extremely premature infants
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Thomas M. Berger, Hans Ulrich Bucher, Ruth Baumann-Hölzle, Manya J. Hendriks, Sabine D. Klein, Jean-Claude Fauchère, University of Zurich, and Fauchère, Jean-Claude
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Parents ,medicine.medical_specialty ,media_common.quotation_subject ,Decision Making ,Empirical survey ,Language area ,Psychological intervention ,610 Medicine & health ,03 medical and health sciences ,0302 clinical medicine ,Quality of life (healthcare) ,030225 pediatrics ,Humans ,Medicine ,2735 Pediatrics, Perinatology and Child Health ,030212 general & internal medicine ,Child ,National data ,media_common ,Extremely premature ,business.industry ,Infant, Newborn ,Infant ,General Medicine ,10027 Clinic for Neonatology ,Caregivers ,Infant, Extremely Premature ,Family medicine ,Pediatrics, Perinatology and Child Health ,Quality of Life ,Aptitude ,business ,Switzerland - Abstract
AIM Due to scarce available national data, this study assessed current attitudes of neonatal caregivers regarding decisions on life-sustaining interventions, and their views on parents' aptitude to express their infant's best interest in shared decision-making. METHODS Self-administered web-based quantitative empirical survey. All 552 experienced neonatal physicians and nurses from all Swiss NICUs were eligible. RESULTS There was a high degree of agreement between physicians and nurses (response rates 79% and 70%, respectively) that the ability for social interactions was a minimal criterion for an acceptable quality of life. A majority stated that the parents' interests are as important as the child's best interest in shared decision-making. Only a minority considered the parents as the best judges of what is their child's best interest. Significant differences in attitudes and values emerged between neonatal physicians and nurses. The language area was very strongly associated with the attitudes of neonatal caregivers. CONCLUSION Despite clear legal requirements and societal expectations for shared decision-making, survey respondents demonstrated a gap between their expressed commitment to shared decision-making and their view on parental aptitude to formulate their infant's best interest. National guidelines need to address these barriers to shared decision-making to promote a more uniform nationwide practice.
- Published
- 2021
211. Synthetic Approaches to Triarylboranes from 1885 to 2020
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Sarina M. Berger, Todd B. Marder, and Matthias Ferger
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010405 organic chemistry ,Chemistry ,boranes ,Organic Chemistry ,Reviews ,Boranes ,General Chemistry ,Review ,Chromophore ,010402 general chemistry ,01 natural sciences ,Combinatorial chemistry ,Catalysis ,Lewis acid ,0104 chemical sciences ,Boranes | Reviews Showcase ,ddc:540 ,synthetic methods ,arylmetalate ,chromophore ,Lewis acids and bases ,Electronic properties - Abstract
In recent years, research in the fields of optoelectronics, anion sensors and bioimaging agents have been greatly influenced by novel compounds containing triarylborane motifs. Such compounds possess an empty p‐orbital at boron which results in useful optical and electronic properties. Such a diversity of applications was not expected when the first triarylborane was reported in 1885. Synthetic approaches to triarylboranes underwent various changes over the following century, some of which are still used in the present day, such as the generally applicable routes developed by Krause et al. in 1922, or by Grisdale et al. in 1972 at Eastman Kodak. Some other developments were not pursued further after their initial reports, such as the synthesis of two triarylboranes bearing three different aromatic groups by Mikhailov et al. in 1958. This review summarizes the development of synthetic approaches to triarylboranes from their first report nearly 135 years ago to the present., This review presents a history of the methods used to synthesize triarylboranes, which are an interesting class of electron‐poor compounds with a wide range of useful properties and applications as Lewis acids, frustrated Lewis pair (FLP) catalysts, electron transporters, luminescent chromophores for OLEDs, anion sensors, and bioimaging agents, among others.
- Published
- 2021
212. A six-year retrospective study of outcomes of surrendered cats (Felis catus) with periuria in a no-kill shelter
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Sophie Liu, Jeannine M. Berger, Sarah Welsh, and Wailani Sung
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education.field_of_study ,CATS ,General Veterinary ,040301 veterinary sciences ,business.industry ,Population ,0402 animal and dairy science ,Psychological intervention ,Retrospective cohort study ,04 agricultural and veterinary sciences ,040201 dairy & animal science ,0403 veterinary science ,Vertical surfaces ,Litter box ,Medicine ,Outcome data ,Felis catus ,business ,education ,Demography - Abstract
Feline house soiling, or the elimination of waste products outside the litter box on horizontal and/or vertical surfaces, is one of the most common owner-reported reasons for cat relinquishment. Because these cats’ perceived low potential for adoption, many sheltering organizations do not accept cats with house-soiling histories or euthanize without further interventions. In this study, cats with periuria were accepted into a limited intake shelter and rehomed. Retrospective data were collected from 294 cats with periuria to assess adoption outcomes over a six-year period. Outcome data included length of stay within the shelter, returns, and euthanasias. Nonparametric statistical tests of significance were used to determine differences in outcomes between cats with periuria and the general cat population in this shelter. Year-by-year analyses demonstrated no significant differences in length of stay for four of the six years analyzed. The rates of returns and euthanasias for both populations were low. These results provide evidence that cats with urinary house-soiling behaviors had similar outcomes as the general cat population. These results argue against immediate refusal or disposal of cats who present to shelters with house-soiling behaviors.
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- 2021
213. Increased Hepatic Lipogenesis Elevates Liver Cholesterol Content
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J.-M. Berger and Young Ah Moon
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Male ,medicine.medical_specialty ,Lipoproteins ,Hypercholesterolemia ,03 medical and health sciences ,chemistry.chemical_compound ,0302 clinical medicine ,Dietary Sucrose ,Internal medicine ,Nonalcoholic fatty liver disease ,medicine ,Animals ,Molecular Biology ,Cells, Cultured ,Triglycerides ,Fatty acid synthesis ,030304 developmental biology ,0303 health sciences ,Cholesterol ,Lipogenesis ,Fatty Acids ,dyslipidemia ,Hypertriglyceridemia ,Fatty liver ,cholesterol ,Feeding Behavior ,Lipid Droplets ,Cell Biology ,General Medicine ,medicine.disease ,Diet ,Fatty Liver ,Mice, Inbred C57BL ,Endocrinology ,Liver ,Receptors, LDL ,chemistry ,Hepatocytes ,lipids (amino acids, peptides, and proteins) ,Cholesterol Esters ,030217 neurology & neurosurgery ,Dyslipidemia ,Research Article ,Lipoprotein - Abstract
Cardiovascular diseases (CVDs) are the most common cause of death in patients with nonalcoholic fatty liver disease (NAFLD) and dyslipidemia is considered at least partially responsible for the increased CVD risk in NAFLD patients. The aim of the present study is to understand how hepatic de novo lipogenesis influences hepatic cholesterol content as well as its effects on the plasma lipid levels. Hepatic lipogenesis was induced in mice by feeding a fat-free/high-sucrose (FF/HS) diet and the metabolic pathways associated with cholesterol were then analyzed. Both liver triglyceride and cholesterol contents were significantly increased in mice fed an FF/HS diet. Activation of fatty acid synthesis driven by the activation of sterol regulatory element binding protein (SREBP)-1c resulted in the increased liver triglycerides. The augmented cholesterol content in the liver could not be explained by an increased cholesterol synthesis, which was decreased by the FF/HS diet. HMG-CoA reductase protein level was decreased in mice fed an FF/HS diet. We found that the liver retained more cholesterol through a reduced excretion of bile acids, a reduced fecal cholesterol excretion, and an increased cholesterol uptake from plasma lipoproteins. Very low-density lipoprotein-triglyceride and -cholesterol secretion were increased in mice fed an FF/HS diet, which led to hypertriglyceridemia and hypercholesterolemia in Ldlr-/- mice, a model that exhibits a more human like lipoprotein profile. These findings suggest that dietary cholesterol intake and cholesterol synthesis rates cannot only explain the hypercholesterolemia associated with NAFLD, and that the control of fatty acid synthesis should be considered for the management of dyslipidemia.
- Published
- 2021
214. Le refus de contact d’un enfant avec un parent dans un contexte de divorce conflictuel – Partie II. Évaluation clinique à partir de l’analyse de 60 situations
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M. Berger and E. Izard
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Psychiatry and Mental health ,Pediatrics, Perinatology and Child Health ,Developmental and Educational Psychology - Abstract
Resume But Les situations ou un enfant ou un adolescent refuse tout contact avec un parent dans le cadre d’un divorce ou d’une separation parentale conflictuelle sont frequentes en pratique pedopsychiatrique et font l’objet de nombreux litiges judiciaires concernant le droit de visite et d’hebergement. Cet article propose des reperes permettant d’identifier les multiples processus en jeu. Population Soixante situations recues en consultations ou en expertises pedopsychiatriques concernant des enfants âges de 3 a 17 ans. Methode Les situations ont ete regroupees en fonction de la maniere dont elles se presentent aux cliniciens ou aux magistrats, puis analysees a partir de nos connaissances cliniques et des recherches dont nous disposons. Resultats Plusieurs configurations cliniques sont apparues frequemment. Chaque comportement de l’enfant, soutien total a un parent, arguments apparemment peu justifies pour refuser le contact, enfant utilisant des phrases toutes faites, plaintes fondees, declaration de maltraitance sexuelle, peut etre interprete de differentes manieres en fonction du contexte clinique. Comprendre les processus en jeu necessite une grande experience clinique et la connaissance des signes de maltraitance chez l’enfant. Le mineur peut avoir des raisons objectives de refuser un contact avec un parent, ou etre projectif a son egard, ou etre pris dans un conflit de loyaute, ou etre sous l’emprise totale d’un parent le plus souvent paranoiaque ou pervers, ou etre maltraite par ce parent. Les auteurs proposent des reperes pour la pratique clinique et expertale, en particulier a partir des travaux quebecois. Cette necessaire rigueur methodologique contraste avec la maniere dont un certain nombre de ces situations sont rapidement qualifiees de syndrome d’alienation parentale, concept refuse par la communaute scientifique. Conclusion Des recherches associant des cliniciens de l’enfance et le systeme judiciaire paraissent necessaires en France pour determiner quels sont les decisions les plus adaptees en fonction de ces differents contextes.
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- 2021
215. Le refus de contact d’un enfant avec un parent dans un contexte de divorce conflictuel – Partie I. Recension des recherches cliniques et judiciaires
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M. Berger
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Psychiatry and Mental health ,Pediatrics, Perinatology and Child Health ,Developmental and Educational Psychology - Abstract
Resume But Cet article presente une revue de la litterature concernant les situations ou un enfant ou un adolescent refuse tout contact avec un parent dans le cadre d’un divorce ou d’une separation parentale conflictuelle. Ces situations, frequentes en pratique pedopsychiatrique, font l’objet de nombreux litiges judiciaires concernant le droit de visite et d’hebergement. Methode Les 16 etudes recensees sont celles qui ont ete realisees conjointement par des cliniciens et des tribunaux depuis 1987, certaines a la demande des ministeres de la justice americains, canadiens, francais. Resultats Ces etudes montrent pourquoi le concept de « syndrome d’alienation parentale » ne doit pas etre utilise, car il aboutit a d’importantes erreurs d’evaluation qui mettent des enfants en danger affectif et physique. L’inscription de ce terme a ete refusee dans le DSM 5 et la CIM 11, etant donne son absence de fondement scientifique. Les fausses allegations d’abus sexuel sont tres rares, entre 0,8 et 6 % des allegations dans les etudes portant sur de grandes series. Plusieurs recherches soulignent l’existence d’un lien statistique entre des violences conjugales anterieures au divorce et des maltraitances exercees sur l’enfant, par le pere, dans le cadre du droit de visite et d’hebergement. Deux etudes longitudinales montrent que 81 % des mineurs reprennent contact spontanement avec le parent « refuse ». Dans les 19 % restant, la plupart des enfants ont des raisons valables de ne pas vouloir rencontrer ce parent. Les situations d’emprise avec lavage de cerveau exercees par des meres ou des peres existent, mais ne representent qu’une minorite des situations de refus. Conclusion Il apparait necessaire de definir la methodologie clinique permettant d’evaluer les processus en jeu lorsqu’un enfant refuse le contact avec un parent et de determiner si la cause en est l’emprise pathologique de la part de l’autre parent sur l’enfant ou d’autres motifs. Ceci fait l’objet d’un autre article.
- Published
- 2021
216. Improved In Situ Characterization of Electrochemical Interfaces Using Metasurface‐Driven Surface‐Enhanced IR Absorption Spectroscopy
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Luca M. Berger, Malo Duportal, Leonardo de Souza Menezes, Emiliano Cortés, Stefan A. Maier, Andreas Tittl, and Katharina Krischer
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Biomaterials ,Electrochemistry ,Condensed Matter Physics ,Electronic, Optical and Magnetic Materials - Published
- 2023
217. Analytical Validation of NavDx, a cfDNA-Based Fragmentomic Profiling Assay for HPV-Driven Cancers
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Alicia Gunning, Sunil Kumar, Cassin Kimmel Williams, Barry M. Berger, Stephen P. Naber, Piyush B. Gupta, Catherine Del Vecchio Fitz, and Charlotte Kuperwasser
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HPV ,OPSCC ,Clinical Biochemistry ,cancer ,NavDx ,oropharyngeal ,profiling assay ,papillomavirus - Abstract
The NavDx® blood test analyzes tumor tissue modified viral (TTMV)-HPV DNA to provide a reliable means of detecting and monitoring HPV-driven cancers. The test has been clinically validated in a large number of independent studies and has been integrated into clinical practice by over 1000 healthcare providers at over 400 medical sites in the US. This Clinical Laboratory Improvement Amendments (CLIA), high complexity laboratory developed test, has also been accredited by the College of American Pathologists (CAP) and the New York State Department of Health. Here, we report a detailed analytical validation of the NavDx assay, including sample stability, specificity as measured by limits of blank (LOBs), and sensitivity illustrated via limits of detection and quantitation (LODs and LOQs). LOBs were 0–0.32 copies/μL, LODs were 0–1.10 copies/μL, and LOQs were
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- 2023
218. Effect of Frozen to Fresh Meat Ratio in Minced Pork on Its Quality
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Igor Tomasevic, Franziska Witte, Rike Elisabeth Kühling, Lisa M. Berger, Monika Gibis, Jochen Weiss, Anja Röser, Matthias Upmann, Eike Joeres, Andreas Juadjur, Ute Bindrich, Volker Heinz, and Nino Terjung
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Fluid Flow and Transfer Processes ,ground pork ,Process Chemistry and Technology ,General Engineering ,General Materials Science ,non-intact cells ,texture ,Instrumentation ,Computer Science Applications - Abstract
The meat industry is typically using a mixture of fresh and frozen meat batters for minced meat production. Our goal was to find the exact threshold for fresh to frozen meat ratio capable of controlling the meat temperature during processing, but without having an adverse effect on the sensory quality of minced pork. To achieve this, the percentage of frozen meat used for the minced pork production was increased from 0% (control) to 50% (maximum) in 10% increments. To keep the minced meat temperature in control and make the processing resistant to fat smearing, the addition of 30% of frozen meat to the meat batter is sufficient. The soluble protein content, instrumental cutting force, and the sensory perceived firmness, juiciness, and inner cohesion were not affected by the addition of frozen meat. However, it has contributed to a significant increase of the drip loss and the amount of non-intact cells (ANIC). With the addition of frozen meat into the minced pork, the compliance to ANIC regulation by the German regulatory authorities is technologically (practically) almost impossible.
- Published
- 2023
219. Noncustodial parents, instrumental networks, and child support compliance
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Quentin H. Riser, Daniel R. Meyer, Lawrence M. Berger, and Vikrant Kamble
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Sociology and Political Science ,Education - Published
- 2023
220. Novel, Hierarchical, MPLS-based Network Architectures and their Role in Migration Strategies towards Future, Optical Packet Switched Internets.
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H. Christiansen and M. Berger
- Published
- 2002
221. Incoherent dimensionality in fisheries management: consequences of misaligned stock assessment and population boundaries
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Dana H. Hanselman, Katelyn M. Bosley, Amy M. Schueller, Jonathan J. Deroba, Brian J. Langseth, Daniel R. Goethel, and Aaron M. Berger
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0106 biological sciences ,education.field_of_study ,Stock assessment ,Ecology ,Natural resource economics ,010604 marine biology & hydrobiology ,Population ,04 agricultural and veterinary sciences ,Aquatic Science ,Oceanography ,01 natural sciences ,040102 fisheries ,Economics ,0401 agriculture, forestry, and fisheries ,Fisheries management ,education ,Ecology, Evolution, Behavior and Systematics ,Curse of dimensionality - Abstract
Fisheries policy inherently relies on an explicit definition of management boundaries that delineate the spatial extent over which stocks are assessed and regulations are implemented. However, management boundaries tend to be static and determined by politically negotiated or historically identified population (or multi-species) units, which create a potential disconnect with underlying, dynamic population structure. The consequences of incoherent management and population or stock boundaries were explored through the application of a two-area spatial simulation–estimation framework. Results highlight the importance of aligning management assessment areas with underlying population structure and processes, especially when fishing mortality is disproportionate to vulnerable biomass among management areas, demographic parameters (growth and maturity) are not homogenous within management areas, and connectivity (via recruitment or movement) unknowingly exists among management areas. Bias and risk were greater for assessments that incorrectly span multiple population segments (PSs) compared to assessments that cover a subset of a PS, and these results were exacerbated when there was connectivity between PSs. Directed studies and due consideration of critical PSs, spatially explicit models, and dynamic management options that help align management and population boundaries would likely reduce estimation biases and management risk, as would closely coordinated management that functions across population boundaries.
- Published
- 2020
222. Household Economic Exclusion among Danish Children: Evaluating Independent and Joint Risks of Income Poverty and Parental Labor Market Exclusion
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Simone Norlund Vering Johansen, Peter Fallesen, Lawrence M. Berger, and Marie Louise Schultz-Nielsen
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Cumulative risk ,Danish ,Sociology and Political Science ,Poverty ,Income poverty ,Childhood poverty ,Economics ,language ,Household income ,Demographic economics ,Social exclusion ,language.human_language - Abstract
Low household income and social exclusion increase children’s risk for unsuccessful transitions to adulthood. Yet we know little about children’s cumulative risk of experiencing poverty and...
- Published
- 2020
223. The Contemporary U.S. Child Welfare System(s): Overview and Key Challenges
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Kristen S. Slack and Lawrence M. Berger
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Annals ,Sociology and Political Science ,Scope (project management) ,Welfare system ,Public economics ,media_common.quotation_subject ,Political science ,Key (cryptography) ,General Social Sciences ,Welfare ,media_common - Abstract
This volume of The ANNALS aims to increase awareness among scholars, policy-makers, and practitioners of the size, scope, and functions of child welfare services in the United States. We aim to promote a wider understanding of the broad impacts of child welfare policies and point to ways in which child welfare services can be better incorporated into cross-cutting social policy debates. The articles in this volume offer concrete recommendations for policies and practices that can reduce child maltreatment, and for systemic approaches—both within the purview of child welfare services and across the broader community and social policy landscape—that can better identify and respond to the needs of children and families in which maltreatment has already occurred or where there is a risk of abuse and neglect. This introduction sets a foundation for understanding the contents of the volume: we provide an overview of child welfare services in the United States and highlight current challenges that the U.S. child welfare systems face.
- Published
- 2020
224. Who Is and Is Not Served by Child Protective Services Systems? Implications for a Prevention Infrastructure to Reduce Child Maltreatment
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Kristen S. Slack and Lawrence M. Berger
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medicine.medical_specialty ,Sociology and Political Science ,Hotline ,media_common.quotation_subject ,05 social sciences ,General Social Sciences ,Neglect ,03 medical and health sciences ,Community response ,0302 clinical medicine ,Welfare system ,030225 pediatrics ,medicine ,0501 psychology and cognitive sciences ,Psychiatry ,Psychology ,050104 developmental & child psychology ,media_common - Abstract
The majority of alleged abuse or neglect reports to the U.S. child welfare system are either screened out prior to an investigation (i.e., at the “hotline” stage) or investigated only to be closed with no finding of immediate child safety concerns. Yet while many of these children and families are at risk of subsequent incidents of child maltreatment or child welfare system involvement, they are not systematically offered services or benefits intended to reduce this risk at the point that child protective services (CPS) ends its involvement. This article provides an overview of the “front end” of the child welfare system, commonly referred to as CPS, highlighting which families are served and which are not. We then argue for a systematic and coordinated child maltreatment prevention infrastructure that incorporates elements of “community response” programs that several U.S. states have implemented in recent years. Such programs are focused on families that have been reported to, and sometimes investigated by, CPS, but no ongoing CPS case is opened. We further argue that such programs need to pay particular attention to economic issues that these families face.
- Published
- 2020
225. Geroscience‐guided repurposing of FDA‐approved drugs to target aging: A proposed process and prioritization
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Ameya S. Kulkarni, Sandra Aleksic, David M. Berger, Felipe Sierra, George A. Kuchel, and Nir Barzilai
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Aging ,Drug Repositioning ,Quality of Life ,Cell Biology ,Geroscience ,Metformin - Abstract
Common chronic diseases represent the greatest driver of rising healthcare costs, as well as declining function, independence, and quality of life. Geroscience-guided approaches seek to delay the onset and progression of multiple chronic conditions by targeting fundamental biological pathways of aging. This approach is more likely to improve overall health and function in old age than treating individual diseases, by addressing aging the largest and mostly ignored risk factor for the leading causes of morbidity in older adults. Nevertheless, challenges in repurposing existing and moving newly discovered interventions from the bench to clinical care have impeded the progress of this potentially transformational paradigm shift. In this article, we propose the creation of a standardized process for evaluating FDA-approved medications for their geroscience potential. Criteria for systematically evaluating the existing literature that spans from animal models to human studies will permit the prioritization of efforts and financial investments for translating geroscience and allow immediate progress on the design of the next Targeting Aging with MEtformin (TAME)-like study involving such candidate gerotherapeutics.
- Published
- 2022
226. Pharmacokinetic Optimization of Small Molecule Janus Kinase 3 Inhibitors to Target Immune Cells
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Julian Laux, Michael Forster, Laura Riexinger, Anna Schwamborn, Jamil Guezguez, Christina Pokoj, Mark Kudolo, Lena M. Berger, Stefan Knapp, Dieter Schollmeyer, Jan Guse, Michael Burnet, and Stefan A. Laufer
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Pharmacology ,Pharmacology (medical) - Abstract
Modulation of Janus kinase/signal transducer and activator of transcription (JAK/STAT) signaling is a promising method of treating autoimmune diseases, and the profound potency of clinical compounds makes this mode of action particularly attractive. Other questions that remain unanswered also include: What is the ideal selectivity between JAK1 and JAK3? Which cells are most relevant to JAK blockade? And what is the ideal tissue distribution pattern for addressing specific autoimmune conditions? We hypothesized that JAK3 selectivity is most relevant to low-dose clinical effects and interleukin-10 (IL-10) stimulation in particular, that immune cells are the most important compartment, and that distribution to inflamed tissue is the most important pharmacokinetic characteristic for
- Published
- 2022
227. Measurements of Strong-Interaction Effects in Kaonic-Helium Isotopes at Sub-eV Precision with X-Ray Microcalorimeters
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T, Hashimoto, S, Aikawa, T, Akaishi, H, Asano, M, Bazzi, D A, Bennett, M, Berger, D, Bosnar, A D, Butt, C, Curceanu, W B, Doriese, M S, Durkin, Y, Ezoe, J W, Fowler, H, Fujioka, J D, Gard, C, Guaraldo, F P, Gustafsson, C, Han, R, Hayakawa, R S, Hayano, T, Hayashi, J P, Hays-Wehle, G C, Hilton, T, Hiraiwa, M, Hiromoto, Y, Ichinohe, M, Iio, Y, Iizawa, M, Iliescu, S, Ishimoto, Y, Ishisaki, K, Itahashi, M, Iwasaki, Y, Ma, T, Murakami, R, Nagatomi, T, Nishi, H, Noda, H, Noumi, K, Nunomura, G C, O'Neil, T, Ohashi, H, Ohnishi, S, Okada, H, Outa, K, Piscicchia, C D, Reintsema, Y, Sada, F, Sakuma, M, Sato, D R, Schmidt, A, Scordo, M, Sekimoto, H, Shi, K, Shirotori, D, Sirghi, F, Sirghi, K, Suzuki, D S, Swetz, A, Takamine, K, Tanida, H, Tatsuno, C, Trippl, J, Uhlig, J N, Ullom, S, Yamada, T, Yamaga, T, Yamazaki, and J, Zmeskal
- Subjects
General Physics and Astronomy - Abstract
We have measured the 3d→2p transition x rays of kaonic ^{3}He and ^{4}He atoms using superconducting transition-edge-sensor microcalorimeters with an energy resolution better than 6 eV (FWHM). We determined the energies to be 6224.5±0.4(stat)±0.2(syst) eV and 6463.7±0.3(stat)±0.1(syst) eV, and widths to be 2.5±1.0(stat)±0.4(syst) eV and 1.0±0.6(stat)±0.3(stat) eV, for kaonic ^{3}He and ^{4}He, respectively. These values are nearly 10 times more precise than in previous measurements. Our results exclude the large strong-interaction shifts and widths that are suggested by a coupled-channel approach and agree with calculations based on optical-potential models.
- Published
- 2022
228. 139 Determination of Population, Demographics, and Location of Equids in Tennessee Using Coggins Test Records and United States Department of Agriculture Census Data
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Amy M Berger, Liesel G Schneider, Matt Horsman, Samantha Beaty, and Jennie L Ivey
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Extension ,Genetics ,Animal Science and Zoology ,General Medicine ,Food Science - Abstract
Knowledge of equine populations and demographics is of vital importance to educational, economic, and health aspects within Tennessee. While the United States Department of Agriculture (USDA) census assesses equids on operations making a set amount of income per year, this method alone may not effectively capture the recreational-use equine population. This study aimed to develop a novel approach of characterizing the population, demographics, and location of equids in Tennessee through annual Coggins test reports and to determine how Coggins test data compared to the USDA census population data. Information was collected from the 2018 Coggins tests (n = 31195), provided by the Tennessee Department of Agriculture, including sex, age, breed, owner location, equid location, and reason for testing. The equine population and location of equids per county (n = 86928) were collected from USDA census data. Statistical analysis was performed using the frequency procedure and means procedure in SAS 9.4. The middle region of Tennessee represented the highest proportion of equids in both the Coggins (60.32%, n = 18816) and USDA (52.05%, n = 45244) data. The counties with the highest proportion of equids from the Coggins data were Putnam (10.21%, n = 3186), Bedford (5.33%, n = 1664), and Shelby (4.18%, n = 1304) whereas the USDA data showed Bedford (4.41%, n = 3832), Williamson (3.38%, n = 2941), and Wilson (3.04%, n = 2643) as the most populated. Per the Coggins data where sex was reported (n = 31073), 48.46% (n = 15059) of the equids were geldings and 51.44% (n = 15983) were mares. Reported breeds within Coggins data (n = 31043) indicated the highest proportion of non-mixed breeds were Quarter Horses (28.20%, n = 8755), Tennessee Walking Horses (22.20%, n = 6892), and Spotted Saddle Horses (7.46%, n = 2316). While neither method fully captures the entire population of the equine industry, assessing both data sets may be helpful in developing targeted strategies for educational programming, population or disease models, and marketing campaigns.
- Published
- 2022
229. A Toolbox for the Generation of Chemical Probes for Baculovirus IAP Repeat Containing Proteins
- Author
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Martin P, Schwalm, Lena M, Berger, Maximilian N, Meuter, James D, Vasta, Cesear R, Corona, Sandra, Röhm, Benedict-Tilman, Berger, Frederic, Farges, Sebastian M, Beinert, Franziska, Preuss, Viktoria, Morasch, Vladimir V, Rogov, Sebastian, Mathea, Krishna, Saxena, Matthew B, Robers, Susanne, Müller, and Stefan, Knapp
- Abstract
E3 ligases constitute a large and diverse family of proteins that play a central role in regulating protein homeostasis by recruiting substrate proteins
- Published
- 2022
230. About micronutrient shortage and definition of deficiency
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Alan Shenkin, Cristina Cuerda, and Mette M. Berger
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Nutrition and Dietetics ,Medicine (miscellaneous) ,Humans ,Nutritional Status ,Micronutrients ,Trace Elements - Published
- 2022
231. SAS CARE 1: Sleep architecture changes in a cohort of patients with Ischemic Stroke/TIA
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S. Miano, F. Fanfulla, L. Nobili, R. Heinzer, J. Haba-Rubio, M. Berger, C.W. Cereda, M.H. Schmidt, M. Manconi, and C.L.A. Bassetti
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Stroke ,Ischemic Attack, Transient ,Polysomnography ,Humans ,610 Medicine & health ,General Medicine ,cardiovascular diseases ,Prospective Studies ,Sleep ,Ischemic Stroke - Abstract
OBJECTIVE Changes in sleep architecture following ischemic stroke have been poorly investigated. Our objective was to explore changes of sleep structure in patients with ischemic stroke or transient ischemic attack in order to verify a possible predictive value of sleep with respect to clinical outcome. METHODS Patients recruited in the prospective SAS-CARE study received two polysomnographies (PSG) in the acute and chronic phases after stroke/TIA. Sleep parameters were compared between the two time-points and matched with a non-stroke population randomly selected from the HypnoLaus cohort. RESULTS Of the 169 patients investigated with PSG in the acute phase, 104 were again studied 3 months after stroke symptom onset and compared with 162 controls. The acute phase of stroke/TIA was associated with sleep disruption, which significantly improved in the chronic phase, but remained worse than controls (total sleep time improve from 318.8 ± 90.8 to 348.4 ± 81.5 min, compared to 388.2 ± 71.3 in controls, sleep latency from 49.9 ± 58.4 to 27.9 min, compared to 20.2 ± 22 in controls, sleep efficiency from 58.2 ± 18.1% to 27.9 ± 36.4 min, compared to 83.4 ± 10.3% in controls, wakefulness after sleep onset percentage from 36.5 ± 17.3 to 29.3 ± 15.6, compared to 13.2 ± 9.2 in controls). The percentage of REM sleep was negatively associated with stroke severity, whereas stroke topography did not correlate with sleep parameters. CONCLUSIONS This study confirmed a severe sleep disruption in the acute phase of stroke. Although a significant improvement of sleep quality was observed during the three months after stroke, sleep architecture did not normalize. In particular, sleep efficiency and REM sleep seem to be particularly affected by stroke in the acute phase, with a relative preservation of NREM sleep. We suggest that these sleep architecture changes represent a persistent marker of brain damage due to stroke. Further studies are needed to assess the relationship with stroke topographic and outcome.
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- 2022
232. ESPEN micronutrient guideline
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Mette M. Berger, Alan Shenkin, Anna Schweinlin, Karin Amrein, Marc Augsburger, Hans-Konrad Biesalski, Stephan C. Bischoff, Michael P. Casaer, Kursat Gundogan, Hanna-Liis Lepp, Angélique M.E. de Man, Giovanna Muscogiuri, Magdalena Pietka, Loris Pironi, Serge Rezzi, Cristina Cuerda, and Muscogiuri, Giovanna
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Chromium ,Vitamin K ,Folic acid ,Monitoring ,Iron ,Riboflavin ,Biotin ,Critical Care and Intensive Care Medicine ,Niacin ,Prescription ,Vitamin ,Choline ,Pantothenic acid ,Selenium ,Dosage ,Carnitine ,Vitamin E ,Micronutrient ,Humans ,Vitamin C ,Micronutrients ,Vitamin D ,Fluoride ,Vitamin A ,Dietary Supplement ,Molybdenum ,Manganese ,Nutrition and Dietetics ,Pyridoxine ,Cobalt ,Vitamins ,Parenteral nutrition ,Cobalamin ,Trace Elements ,Zinc ,Dietary Supplements ,Thiamin ,Trace element ,Deficiency ,Coenzyme Q10 ,Enteral nutrition ,Copper ,Diagnosi ,Iodine ,Human - Abstract
BACKGROUND: Trace elements and vitamins, named together micronutrients (MNs), are essential for human metabolism. Recent research has shown the importance of MNs in common pathologies, with significant deficiencies impacting the outcome. OBJECTIVE: This guideline aims to provide information for daily clinical nutrition practice regarding assessment of MN status, monitoring, and prescription. It proposes a consensus terminology, since many words are used imprecisely, resulting in confusion. This is particularly true for the words "deficiency", "repletion", "complement", and "supplement". METHODS: The expert group attempted to apply the 2015 standard operating procedures (SOP) for ESPEN which focuses on disease. However, this approach could not be applied due to the multiple diseases requiring clinical nutrition resulting in one text for each MN, rather than for diseases. An extensive search of the literature was conducted in the databases Medline, PubMed, Cochrane, Google Scholar, and CINAHL. The search focused on physiological data, historical evidence (published before PubMed release in 1996), and observational and/or randomized trials. For each MN, the main functions, optimal analytical methods, impact of inflammation, potential toxicity, and provision during enteral or parenteral nutrition were addressed. The SOP wording was applied for strength of recommendations. RESULTS: There was a limited number of interventional trials, preventing meta-analysis and leading to a low level of evidence. The recommendations underwent a consensus process, which resulted in a percentage of agreement (%): strong consensus required of >90% of votes. Altogether the guideline proposes sets of recommendations for 26 MNs, resulting in 170 single recommendations. Critical MNs were identified with deficiencies being present in numerous acute and chronic diseases. Monitoring and management strategies are proposed. CONCLUSION: This guideline should enable addressing suboptimal and deficient status of a bundle of MNs in at-risk diseases. In particular, it offers practical advice on MN provision and monitoring during nutritional support. ispartof: Clinical Nutrition vol:41 issue:6 ispartof: location:England status: Published online
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- 2022
233. Embryonic osteocalcin signaling determines lifelong adrenal steroidogenesis and homeostasis in the mouse
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Vijay K. Yadav, Julian M. Berger, Parminder Singh, Perumal Nagarajan, and Gerard Karsenty
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Mice, Knockout ,Hypothalamo-Hypophyseal System ,Mice ,Adrenal Glands ,Osteocalcin ,Animals ,Homeostasis ,Pituitary-Adrenal System ,Female ,General Medicine ,Glucocorticoids ,Macaca mulatta ,Signal Transduction - Abstract
Through their ability to regulate gene expression in most organs, glucocorticoid (GC) hormones influence numerous physiological processes and are therefore key regulators of organismal homeostasis. In bone, GC hormones inhibit expression of the hormone Osteocalcin for poorly understood reasons. Here, we show that in a classical endocrine feedback loop, osteocalcin in return enhanced the biosynthesis of GC as well as mineralocorticoid hormones (adrenal steroidogenesis) in rodents and primates. Conversely, inactivation of osteocalcin signaling in adrenal glands significantly impaired adrenal growth and steroidogenesis in mice. Embryo-made osteocalcin was necessary for normal Sf1 expression in fetal adrenal cells and adrenal cell steroidogenic differentiation and therefore determined the number of steroidogenic cells present in the adrenal glands of adult animals. Embryonic, not postnatal, osteocalcin also governed adrenal growth, adrenal steroidogenesis, blood pressure, electrolyte equilibrium, and the rise in circulating corticosterone levels during the acute stress response in adult offspring. This osteocalcin-dependent regulation of adrenal development and steroidogenesis occurred even in the absence of a functional hypothalamus/pituitary/adrenal axis and explains why osteocalcin administration during pregnancy promoted adrenal growth and steroidogenesis and improved the survival of adrenocorticotropic hormone signaling-deficient animals. This study reveals that a bone-derived embryonic hormone influences lifelong adrenal functions and organismal homeostasis in the mouse.
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- 2022
234. Management of gastrointestinal failure in the adult critical care setting
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Mette M. Berger and Claire-Anne Hurni
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Adult ,Parenteral Nutrition ,Enteral Nutrition ,Critical Care ,Organ Dysfunction Scores ,Critical Illness ,Humans ,Critical Care and Intensive Care Medicine - Abstract
Gastrointestinal failure is a polymorphic syndrome with multiple causes. Managing the different situations from a practical, metabolic, and nutritional point of view is challenging, which the present review will try to address.Acute gastrointestinal injury (AGI) has been defined and has evolved into a concept of gastrointestinal dysfunction score (GIDS) built on the model of Sequential Organ Failure Assessment (SOFA) score, and ranging from 0 (no risk) to 4 (life threatening). But there is yet no specific, reliable and reproducible, biomarker linked to it. Evaluating the risk with the Nutrition Risk Screening (NRS) score is the first step whenever addressing nutrition therapy. Depending on the severity of the gastrointestinal failure and its clinical manifestations, nutritional management needs to be individualized but always including prevention of undernutrition and dehydration, and administration of target essential micronutrients. The use of fibers in enteral feeding solutions has gained acceptance and is even recommended based on microbiome findings. Parenteral nutrition whether alone or combined to enteral feeding is indicated whenever the intestine is unable to process the needs.The heterogeneity of gastrointestinal insufficiency precludes a uniform nutritional management of all critically ill patients but justifies its early detection and the implementation of individualized care.
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- 2022
235. Clinical evaluation of the new indirect calorimeter in canopy and face mask mode for energy expenditure measurement in spontaneously breathing patients
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Yves M. Dupertuis, Marta Delsoglio, Katrin Hamilton-James, Mette M. Berger, Claude Pichard, Tinh-Hai Collet, and Laurence Genton
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Adult ,Male ,Analysis of Variance ,Nutrition and Dietetics ,Rest ,Masks ,Humans ,Reproducibility of Results ,Calorimetry, Indirect ,Basal Metabolism ,Critical Care and Intensive Care Medicine ,Energy Metabolism - Abstract
The new indirect calorimeter developed in the framework of the ICALIC project was first evaluated in ventilation mode. This second phase aimed to compare its ease of use and precision with another commonly used device in spontaneously breathing adult patients using a canopy hood or a face mask.The time required to measure resting energy expenditure (REE) with Q-NRG® in canopy and face mask mode was compared with Quark RMR® in canopy mode by sequential measurements in 45 and 40 spontaneously breathing adult patients, respectively. Their precision was assessed at different time intervals, using coefficients of variation (CV%) and repeated measures one-way ANOVA. Agreement between the two devices was evaluated by correlation coefficients, Bland-Altman plots, and paired t-test. Patients' characteristics potentially affecting the measurement were assessed using linear regression analysis.REE measurement with Q-NRG® was faster than Quark RMR® (19.7 ± 2.9 min vs 24.5 ± 4.3 min, P 0.001). In canopy mode, Q-NRG® gave values similar to Quark RMR®, with 73% of patients achieving a steady state (CV%10%) within the 5-15 min interval. In face mask mode, Q-NRG® was less stable than Quark RMR® in canopy mode, and steady state was achieved in only 40% of the patients within the 5-15 min interval. Correlation between the two devices was stronger when Q-NRG® was used in canopy than in face mask mode, with Pearson coefficients of 0.96 and 0.86, respectively. Compared to Quark RMR® in canopy mode, systematic bias±1.96∗SD with Q-NRG® was -14 ± 236 kcal/day in canopy and 73 ± 484 kcal/day in face mask mode. Q-NRG® in face mask mode overestimated REE by 150 ± 51 kcal/day in men compared to Quark RMR® in canopy mode.Q-NRG® in canopy mode made it possible to save at least 5 min compared to Quark RMR® while maintaining the same measurement precision. However, its use in face mask mode could lead to REE overestimation in men and, therefore, should not be recommended in the clinical setting.ClinicalTrials.gov no. NCT03947294.
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- 2022
236. Third dose of SARS-CoV-2 vaccination in hemato-oncological patients and health care workers: immune responses and adverse events – a retrospective cohort study
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Maximilian J. Mair, Julia M. Berger, Manfred Mitterer, Margaretha Gansterer, Arne C. Bathke, Wolfgang Trutschnig, Anna S. Berghoff, Thomas Perkmann, Helmuth Haslacher, Wolfgang W. Lamm, Markus Raderer, Selma Tobudic, Thorsten Fuereder, Thomas Buratti, Dominic Fong, and Matthias Preusser
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Cancer Research ,COVID-19 Vaccines ,SARS-CoV-2 ,Health Personnel ,oncology ,Immunity ,Humans ,COVID-19 ,cancer ,vaccination ,Retrospective Studies ,Original Research - Abstract
Background Due to potentially immune-escaping virus variants and waning immunity, a third SARS-CoV-2 vaccination dose is increasingly recommended. However, data in patients with cancer are limited. Patients and methods We measured anti-SARS-CoV-2 spike protein antibody levels after the third vaccination dose in 439 patients with cancer and 41 health care workers (HCW) at an academic center in Austria and a rural community hospital in Italy. Adverse events were retrieved from questionnaires. Results Overall, 439 patients and 41 HCW were included. SARS-CoV-2 infections were observed in 62/439 (14.1%) patients before vaccination and in 5/439 (1.1%) patients after ≥1 dose. Longitudinal analysis revealed a decrease of antibody levels between 3 and 6 months after second vaccination in patients with solid tumors (p
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- 2022
237. Expression of the Immune Checkpoint Protein VISTA Is Differentially Regulated by the TGF-β1 – Smad3 Signaling Pathway in Rapidly Proliferating Human Cells and T Lymphocytes
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Stephanie Schlichtner, Inna M. Yasinska, Sabrina Ruggiero, Steffen M. Berger, Nijas Aliu, Mateja Prunk, Janko Kos, N. Helge Meyer, Bernhard F. Gibbs, Elizaveta Fasler-Kan, and Vadim V. Sumbayev
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galectin-9 ,Medicine (General) ,R5-920 ,T lymphocytes ,VISTA ,anti-cancer immunity ,immune checkpoint - Abstract
Immune checkpoint proteins play crucial roles in human embryonic development but are also used by cancer cells to escape immune surveillance. These proteins and biochemical pathways associated with them form a complex machinery capable of blocking the ability of cytotoxic immune lymphoid cells to attack cancer cells and, ultimately, to fully suppress anti-tumor immunity. One of the more recently discovered immune checkpoint proteins is V-domain Ig-containing suppressor of T cell activation (VISTA), which plays a crucial role in anti-cancer immune evasion pathways. The biochemical mechanisms underlying regulation of VISTA expression remain unknown. Here, we report for the first time that VISTA expression is controlled by the transforming growth factor beta type 1 (TGF-β)-Smad3 signaling pathway. However, in T lymphocytes, we found that VISTA expression was differentially regulated by TGF-β depending on their immune profile. Taken together, our results demonstrate the differential biochemical control of VISTA expression in human T cells and various types of rapidly proliferating cells, including cancer cells, fetal cells and keratinocytes.
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- 2022
238. 14 CO2 Utilization: Methane, Methanol, and Synthetic Fuels
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Cornelius M. Berger, Martin Muhler, Jan Van De Loosdrecht, Hans J. W. Niemantsverdriet, Edward Kunkes, Klaus Friedel Ortega, and Malte Behrens
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- 2022
239. Perspective: Role of Micronutrients and Omega-3 Long-Chain Polyunsaturated Fatty Acids for Immune Outcomes of Relevance to Infections in Older Adults-A Narrative Review and Call for Action
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Manfred Eggersdorfer, Mette M Berger, Philip C Calder, Adrian F Gombart, Emily Ho, Alessandro Laviano, and Simin N Meydani
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immunosenescence ,eicosapentaenoic acid ,Nutrition and Dietetics ,vitamin ,Medicine (miscellaneous) ,trace element ,COVID-19 ,Ascorbic Acid ,Vitamins ,docosahexaenoic acid ,Selenium ,Zinc ,Fatty Acids, Omega-3 ,Humans ,inflammaging ,viral infection ,Micronutrients ,influenza ,Pandemics ,older adults ,Food Science ,Aged - Abstract
The immune system is weakened by advancing age, often referred to as immunosenescence, increasing the vulnerability to, and frequently the severity of, infectious diseases in older people. This has become very apparent in the current coronavirus disease 2019 (COVID-19) pandemic for which older people are at higher risk of severe outcomes, even those who are fully vaccinated. Aging affects both the innate and adaptive immune systems and is characterized by an imbalanced inflammatory response. Increasing evidence shows that optimal status of nutrients such as vitamins C, D, and E and selenium and zinc as well as the omega-3 (n-3) fatty acids DHA and EPA can help compensate for these age-related changes. While inadequate intakes of these nutrients are widespread in the general population, this is often more pronounced in older people. Maintaining adequate intakes is a challenge for them due to a range of factors such as physical, physiological, and cognitive changes; altered absorption; and the presence of noncommunicable diseases. While nutritional requirements are ideally covered by a balanced diet, this can be difficult to achieve, particularly for older people. Fortified foods and nutritional complements are effective in achieving adequate micronutrient intakes and should be considered as a safe and cost-effective means for older people to improve their nutritional status and hence support their defense against infections. Complementing the diet with a combination of micronutrients, particularly those playing a key role in the immune system such as vitamins C, D, and E and selenium and zinc as well as DHA and EPA, is recommended for older people. Optimal nutrition to support the immune system in older people will remain essential, particularly in the face of the current COVID-19 pandemic and, thus, developing strategies to ensure adequate nutrition for the growing number of older adults will be an important and cost-effective investment in the future.
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- 2022
240. Inclusive and differential cross section measurements of single top quark production in association with a Z boson in proton-proton collisions at root s=13 TeV
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Tumasyan, A. Adam, W. Andrejkovic, J. W. Bergauer, T. and Chatterjee, S. Damanakis, K. Dragicevic, M. Del Valle, A. Escalante Fruhwirth, R. Jeitler, M. Krammer, N. Lechner, L. Liko, D. Mikulec, I Paulitsch, P. Pitters, F. M. and Schieck, J. Schofbeck, R. Schwarz, D. Templ, S. and Waltenberger, W. Wulz, C-E Chekhovsky, V Litomin, A. and Makarenko, V Darwish, M. R. De Wolf, E. A. Janssen, T. and Kello, T. Lelek, A. Sfar, H. Rejeb Van Mechelen, P. Van Putte, S. Van Remortel, N. Blekman, F. Bols, E. S. and D'Hondt, J. Delcourt, M. El Faham, H. Lowette, S. and Moortgat, S. Morton, A. Muller, D. Sahasransu, A. R. and Tavernier, S. Van Doninck, W. Stylianou, N. Beghin, D. and Bilin, B. Clerbaux, B. De Lentdecker, G. Favart, L. and Grebenyuk, A. Kalsi, A. K. Lee, K. Mahdavikhorrami, M. and Makarenko, I Moureaux, L. Petre, L. Popov, A. Postiau, N. Starling, E. Thomas, L. Vanden Bemden, M. Vander Velde, C. Vanlaer, P. Gao, X. Cornelis, T. Dobur, D. and Knolle, J. Lambrecht, L. Mestdach, G. Niedziela, M. and Roskas, C. Samalan, A. Skovpen, K. Tytgat, M. Vermassen, B. Wezenbeek, L. Benecke, A. Bethani, A. Bruno, G. and Bury, F. Caputo, C. David, P. Delaere, C. Donertas, I. S. Giammanco, A. Jaffel, K. Jain, Sa Lemaitre, V and Mondal, K. Prisciandaro, J. Taliercio, A. Teklishyn, M. and Tran, T. T. Vischia, P. Wertz, S. Alves, G. A. Hensel, C. Moraes, A. Teles, P. Rebello Alda Junior, W. L. Gallo Pereira, M. Alves Ferreira Filho, M. Barroso Malbouisson, H. Brandao Carvalho, W. Chinellato, J. Da Costa, E. M. Da Silveira, G. G. Damiao, D. De Jesus De Souza, S. Fonseca and Herrera, C. Mora Amarilo, K. Mota Mundim, L. Nogima, H. and Santoro, A. Silva Do Amaral, S. M. Sznajder, A. Thiel, M. and De Araujo, F. Torres Da Silva Pereira, A. Vilela Bernardes, C. A. Calligaris, L. Tomei, T. R. Fernandez Perez Gregores, E. M. Lemos, D. S. Mercadante, P. G. Novaes, S. F. and Padula, Sandra S. Aleksandrov, A. Antchev, G. Hadjiiska, R. and Iaydjiev, P. Misheva, M. Rodozov, M. Shopova, M. and Sultanov, G. Dimitrov, A. Ivanov, T. Litov, L. Pavlov, B. Petkov, P. Petrov, A. Cheng, T. Javaid, T. and Mittal, M. Yuan, L. Ahmad, M. Bauer, G. Dozen, C. and Hu, Z. Martins, J. Wang, Y. Yi, K. Chapon, E. Chen, G. M. Chen, H. S. Chen, M. Iemmi, F. Kapoor, A. and Leggat, D. Liao, H. Liu, Z-A Milosevic, V Monti, F. and Sharma, R. Tao, J. Thomas-Wilsker, J. Wang, J. Zhang, H. and Zhao, J. Agapitos, A. An, Y. Ban, Y. Chen, C. and Levin, A. Li, Q. Lyu, X. Mao, Y. Qian, S. J. Wang, D. Xiao, J. Lu, M. You, Z. Okawa, H. Zhang, Y. and Zhang, L. Lin, Z. Xiao, M. Avila, C. Cabrera, A. and Florez, C. Fraga, J. Mejia Guisao, J. Ramirez, F. Ruiz Alvarez, J. D. Salazar Gonzalez, C. A. Giljanovic, D. and Godinovic, N. Lelas, D. Puljak, I Antunovic, Z. Kovac, M. Sculac, T. Brigljevic, V Ferencek, D. Majumder, D. and Roguljic, M. Starodumov, A. Susa, T. Attikis, A. and Christoforou, K. Erodotou, E. Ioannou, A. Kole, G. and Kolosova, M. Konstantinou, S. Mousa, J. Nicolaou, C. and Ptochos, F. Razis, P. A. Rykaczewski, H. Saka, H. and Finger, M. Finger Jr, M. Jr Kveton, A. Ayala, E. Carrera Jarrin, E. Abdalla, H. Assran, Y. Lotfy, A. Mahmoud, M. A. Bhowmik, S. Dewanjee, R. K. Ehataht, K. Kadastik, M. and Nandan, S. Nielsen, C. Pata, J. Raidal, M. Tani, L. and Veelken, C. Eerola, P. Forthomme, L. Kirschenmann, H. and Osterberg, K. Voutilainen, M. Bharthuar, S. Brucken, E. and Garcia, F. Havukainen, J. Kim, M. S. Kinnunen, R. and Lampen, T. Lassila-Perini, K. Lehti, S. Linden, T. and Lotti, M. Martikainen, L. Myllymaki, M. Ott, J. and Siikonen, H. Tuominen, E. Tuominiemi, J. Luukka, P. and Petrow, H. Tuuva, T. Amendola, C. Besancon, M. Couderc, F. Dejardin, M. Denegri, D. Faure, J. L. Ferri, F. and Ganjour, S. Gras, P. de Monchenault, G. Hamel Jarry, P. and Lenzi, B. Locci, E. Malcles, J. Rander, J. Rosowsky, A. and Sahin, M. O. Savoy-Navarro, A. Titov, M. Yu, G. B. and Mijuskovic, J. Ahuja, S. Beaudette, F. Bonanomi, M. and Perraguin, A. Buchot Busson, P. Cappati, A. Charlot, C. and Davignon, O. Diab, B. Falmagne, G. Ghosh, S. de Cassagnac, R. Granier Hakimi, A. Kucher, I Motta, J. and Nguyen, M. Ochando, C. Paganini, P. Rembser, J. Salerno, R. Sarkar, U. Sauvan, J. B. Sirois, Y. Tarabini, A. and Zabi, A. Zghiche, A. Agram, J-L Andrea, J. Apparu, D. and Bloch, D. Bourgatte, G. Brom, J-M Chabert, E. C. and Collard, C. Darej, D. Fontaine, J-C Goerlach, U. and Grimault, C. Le Bihan, A-C Nibigira, E. Van Hove, P. and Asilar, E. Beauceron, S. Bernet, C. Boudoul, G. Camen, C. Carle, A. Chanon, N. Contardo, D. Depasse, P. El Mamouni, H. Fay, J. Gascon, S. Gouzevitch, M. Ille, B. and Laktineh, I. B. Lattaud, H. Lesauvage, A. Lethuillier, M. Mirabito, L. Perries, S. Shchablo, K. Sordini, V and Torterotot, L. Touquet, G. Vander Donckt, M. Viret, S. and Lomidze, I Toriashvili, T. Tsamalaidze, Z. Mestvirishvili, A. Botta, V Feld, L. Klein, K. Lipinski, M. Meuser, D. Pauls, A. Rowert, N. Schulz, J. Teroerde, M. and Dodonova, A. Eliseev, D. Erdmann, M. Fackeldey, P. and Fischer, B. Hebbeker, T. Hoepfner, K. Ivone, F. and Mastrolorenzo, L. Merschmeyer, M. Meyer, A. Mocellin, G. and Mondal, S. Mukherjee, S. Noll, D. Novak, A. Pook, T. and Pozdnyakov, A. Rath, Y. Reithler, H. Roemer, J. Schmidt, A. Schuler, S. C. Sharma, A. Vigilante, L. Wiedenbeck, S. Zaleski, S. Borras, K. Kasem, A. Coubez, X. and Dziwok, C. Flugge, G. Ahmad, W. Haj Hlushchenko, O. and Kress, T. Nowack, A. Pistone, C. Pooth, O. Roy, D. and Stahl, A. Ziemons, T. Zotz, A. Petersen, H. Aarup and Martin, M. Aldaya Asmuss, P. Baxter, S. Bayatmakou, M. and Behnke, O. Martinez, A. Bermudez Bhattacharya, S. Bin Anuar, A. A. Brunner, D. Campbell, A. Cardini, A. Cheng, C. and Colombina, F. Rodriguez, S. Consuegra Silva, G. Correia and Danilov, V De Silva, M. Didukh, L. Eckerlin, G. and Eckstein, D. Banos, L. I. Estevez Filatov, O. Gallo, E. and Geiser, A. Giraldi, A. Grohsjean, A. Guthoff, M. Jafari, A. Jomhari, N. Z. Jung, H. Kasemann, M. Kaveh, H. and Kleinwort, C. Kogler, R. Krucker, D. Lange, W. Lidrych, J. Lipka, K. Lohmann, W. Mankel, R. Melzer-Pellmann, I-A and Morentin, M. Mendizabal Metwally, J. Meyer, A. B. Meyer, M. Mnich, J. Mussgiller, A. Otarid, Y. Adan, D. Perez and Pitzl, D. Raspereza, A. Lopes, B. Ribeiro Rubenach, J. and Saggio, A. Saibel, A. Savitskyi, M. Scham, M. and Scheurer, V Schnake, S. Schutze, P. Schwanenberger, C. and Shchedrolosiev, M. Ricardo, R. E. Sosa Stafford, D. Tonon, N. Van De Klundert, M. Walsh, R. Walter, D. Wang, Q. and Wen, Y. Wichmann, K. Wiens, L. Wissing, C. Wuchterl, S. and Bakhshiansohi, H. Aggleton, R. Albrecht, S. Bein, S. and Benato, L. Connor, P. De Leo, K. Eich, M. Feindt, F. and Frohlich, A. Garbers, C. Garutti, E. Gunnellini, P. and Hajheidari, M. Haller, J. Hinzmann, A. Kasieczka, G. and Klanner, R. Kramer, T. Kutzner, V Lange, J. Lange, T. and Lobanov, A. Malara, A. Nigamova, A. Rodriguez, K. J. Pena Rieger, M. Rieger, O. Schleper, P. Schroder, M. and Schwandt, J. Sonneveld, J. Stadie, H. Steinbruck, G. and Tews, A. Zoi, I Bechtel, J. Brommer, S. Burkart, M. and Butz, E. Caspart, R. Chwalek, T. De Boer, W. Dierlamm, A. Droll, A. El Morabit, K. Faltermann, N. Giffels, M. and Gosewisch, J. O. Gottmann, A. Hartmann, F. Heidecker, C. and Husemann, U. Keicher, P. Koppenhofer, R. Maier, S. and Metzler, M. Mitra, S. Muller, Th Neukum, M. Nurnberg, A. and Quast, G. Rabbertz, K. Rauser, J. Savoiu, D. and Schnepf, M. Seith, D. Shvetsov, I Simonis, H. J. Ulrich, R. Van der Linden, J. Von Cube, R. F. Wassmer, M. Weber, M. Wieland, S. Wolf, R. Wozniewski, S. Wunsch, S. and Anagnostou, G. Daskalakis, G. Geralis, T. Kyriakis, A. and Loukas, D. Stakia, A. Diamantopoulou, M. Karasavvas, D. and Karathanasis, G. Kontaxakis, P. Koraka, C. K. and Manousakis-Katsikakis, A. Panagiotou, A. Papavergou, I and Saoulidou, N. Theofilatos, K. Tziaferi, E. Vellidis, K. and Vourliotis, E. Sphicas, P. Bakas, G. Kousouris, K. and Papakrivopoulos, I Tsipolitis, G. 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Herndon, M. Herve, A. and Hussain, U. Lanaro, A. Loeliger, A. Loveless, R. and Sreekala, J. Madhusudanan Mallampalli, A. Mohammadi, A. and Pinna, D. Savin, A. Shang, V Smith, W. H. Teague, D. and Trembath-Reichert, S. Vetens, W. CMS Collaboration
- Subjects
High Energy Physics::Phenomenology ,High Energy Physics::Experiment ,Nuclear Experiment - Abstract
Inclusive and differential cross sections of single top quark production in association with a Z boson are measured in proton-proton collisions at a center-of-mass energy of 13 TeV with a data sample corresponding to an integrated luminosity of 138 fb(-1) recorded by the CMS experiment. Events are selected based on the presence of three leptons, electrons or muons, associated with leptonic Z boson and top quark decays. The measurement yields an inclusive cross section of 87.9(-7.3)(+7.5) (stat)(-6.0)(+7.3)(syst) fb for a dilepton invariant mass greater than 30 GeV, in agreement with standard model (SM) calculations and represents the most precise determination to date. The ratio between the cross sections for the top quark and the top antiquark production in association with a Z boson is measured as 2.37(-0.42)(+0.56)(stat)(-0.13)(+0.27) (syst). Differential measurements at parton and particle levels are performed for the first time. Several kinematic observables are considered to study the modeling of the process. Results are compared to theoretical predictions with different assumptions on the source of the initial-state b quark and found to be in agreement, within the uncertainties. Additionally, the spin asymmetry, which is sensitive to the top quark polarization, is determined from the differential distribution of the polarization angle at parton level to be 0.54 +/- 0.16 (stat)+/- 0.06 (syst), in agreement with SM predictions.
- Published
- 2022
241. Measurement and QCD analysis of double-differential inclusive jet cross sections in proton-proton collisions at root s=13 TeV
- Author
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Chen, X. Cheng, Y. Cranshaw, D. J. and Hogan, S. Monroy, J. Patterson, J. R. Quach, D. and Reichert, J. Reid, M. Ryd, A. Sun, W. Thom, J. and Wittich, P. Zou, R. Albrow, M. Alyari, M. Apollinari, G. and Apresyan, A. Apyan, A. Banerjee, S. Bauerdick, L. A. T. and Berry, D. Berryhill, J. Bhat, P. C. Burkett, K. and Butler, J. N. Canepa, A. Cerati, G. B. Cheung, H. W. K. and Chlebana, F. Di Petrillo, K. F. Elvira, V. D. Feng, Y. and Freeman, J. Gecse, Z. Gray, L. Green, D. Grunendahl, S. and Gutsche, O. Harris, R. M. Heller, R. Herwig, T. C. and Hirschauer, J. Jayatilaka, B. Jindariani, S. Johnson, M. and Joshi, U. Klijnsma, T. Klima, B. Kwok, K. H. M. Lammel, S. Lincoln, D. Lipton, R. Liu, T. Madrid, C. and Maeshima, K. Mantilla, C. Mason, D. McBride, P. Merkel, P. Mrenna, S. Nahn, S. Ngadiuba, J. O'Dell, V. and Papadimitriou, V. Pedro, K. Pena, C. Prokofyev, O. and Ravera, F. Reinsvold Hall, A. Ristori, L. Sexton-Kennedy, E. and Smith, N. Soha, A. Spalding, W. J. Spiegel, L. and Stoynev, S. Strait, J. Taylor, L. Tkaczyk, S. Tran, N. V. Uplegger, L. Vaandering, E. W. Weber, H. A. Acosta, D. Avery, P. Bourilkov, D. Cadamuro, L. Cherepanov, V. and Errico, F. Field, R. D. Guerrero, D. Joshi, B. M. and Kim, M. Koenig, E. Konigsberg, J. Korytov, A. Lo, K. H. and Matchev, K. Menendez, N. Mitselmakher, G. Muthirakalayil Madhu, A. Rawal, N. Rosenzweig, D. Rosenzweig, S. and Rotter, J. Shi, K. Sturdy, J. Wang, J. Yigitbasi, E. and Zuo, X. Adams, T. Askew, A. Habibullah, R. Hagopian, V. and Johnson, K. F. Khurana, R. Kolberg, T. Martinez, G. and Prosper, H. Schiber, C. Viazlo, O. Yohay, R. Zhang, J. and Baarmand, M. M. Butalla, S. Elkafrawy, T. Hohlmann, M. and Kumar Verma, R. Noonan, D. Rahmani, M. Yumiceva, F. and Adams, M. R. Becerril Gonzalez, H. Cavanaugh, R. Dittmer, S. and Evdokimov, O. Gerber, C. E. Hangal, D. A. Hofman, D. J. and Merrit, A. H. Mills, C. Oh, G. Roy, T. Rudrabhatla, S. Tonjes, M. B. Varelas, N. Viinikainen, J. Wang, X. and Wu, Z. Ye, Z. Alhusseini, M. Dilsiz, K. Gandrajula, R. P. Koseyan, O. K. Merlo, J. -P. Mestvirishvili, A. and Nachtman, J. Ogul, H. Onel, Y. Penzo, A. Snyder, C. and Tiras, E. Amram, O. Blumenfeld, B. Corcodilos, L. Davis, J. Eminizer, M. Gritsan, A. V. Kyriacou, S. Maksimovic, P. Roskes, J. Swartz, M. Vami, T. A. Abreu, A. and Anguiano, J. Baldenegro Barrera, C. Baringer, P. Bean, A. and Bylinkin, A. Flowers, Z. Isidori, T. Khalil, S. and King, J. Krintiras, G. Kropivnitskaya, A. Lazarovits, M. and Le Mahieu, C. Lindsey, C. Marquez, J. Minafra, N. and Murray, M. Nickel, M. Rogan, C. Royon, C. Salvatico, R. and Sanders, S. Schmitz, E. Smith, C. Tapia Takaki, J. D. and Wang, Q. Warner, Z. Williams, J. Wilson, G. Duric, S. Ivanov, A. Kaadze, K. Kim, D. Maravin, Y. and Mitchell, T. Modak, A. Nam, K. Rebassoo, F. Wright, D. and Adams, E. Baden, A. Baron, O. Belloni, A. Eno, S. C. and Hadley, N. J. Jabeen, S. Kellogg, R. G. Koeth, T. and Mignerey, A. C. Nabili, S. Palmer, C. Seidel, M. Skuja, A. Wang, L. Wong, K. Abercrombie, D. Andreassi, G. and Bi, R. Busza, W. Cali, I. A. Chen, Y. D'Alfonso, M. and Eysermans, J. Freer, C. Gomez Ceballos, G. Goncharov, M. and Harris, P. Hu, M. Klute, M. Kovalskyi, D. Krupa, J. and Lee, Y. -J. Mironov, C. Paus, C. Rankin, D. Roland, C. and Roland, G. Shi, Z. Stephans, G. S. F. Wang, J. Wang, Z. Wyslouch, B. Chatterjee, R. M. Evans, A. Hiltbrand, J. Jain, Sh. Krohn, M. Kubota, Y. Mans, J. Revering, M. Rusack, R. Saradhy, R. Schroeder, N. Strobbe, N. and Wadud, M. A. Bloom, K. Bryson, M. Chauhan, S. Claes, D. R. Fangmeier, C. Finco, L. Golf, F. Joo, C. and Kravchenko, I. Musich, M. Reed, I. Siado, J. E. Snow, G. R. Tabb, W. Yan, F. Zecchinelli, A. G. Agarwal, G. and Bandyopadhyay, H. Hay, L. Iashvili, I. Kharchilava, A. and McLean, C. Nguyen, D. Pekkanen, J. Rappoccio, S. and Williams, A. Alverson, G. Barberis, E. Haddad, Y. and Hortiangtham, A. Li, J. Madigan, G. Marzocchi, B. Morse, D. M. Nguyen, V. Orimoto, T. Parker, A. Skinnari, L. and Tishelman-Charny, A. Wamorkar, T. Wang, B. Wisecarver, A. and Wood, D. Bhattacharya, S. Bueghly, J. Chen, Z. and Gilbert, A. Gunter, T. Hahn, K. A. Liu, Y. Odell, N. and Schmitt, M. H. Velasco, M. Band, R. Bucci, R. Cremonesi, M. Das, A. Dev, N. Goldouzian, R. Hildreth, M. and Hurtado Anampa, K. Jessop, C. Lannon, K. Lawrence, J. and Loukas, N. Lutton, D. Marinelli, N. Mcalister, I. and McCauley, T. Mcgrady, C. Mohrman, K. Moore, C. Musienko, Y. Ruchti, R. Siddireddy, P. Townsend, A. Wayne, M. and Wightman, A. Zarucki, M. Zygala, L. Bylsma, B. Cardwell, B. Durkin, L. S. Francis, B. Hill, C. Nunez Ornelas, M. and Wei, K. Winer, B. L. Yates, B. R. Addesa, F. M. and Bonham, B. Das, P. Dezoort, G. Elmer, P. Frankenthal, A. and Greenberg, B. Haubrich, N. Higginbotham, S. and Kalogeropoulos, A. Kopp, G. Kwan, S. Lange, D. Marlow, D. Mei, K. Ojalvo, I. Olsen, J. Stickland, D. Tully, C. Malik, S. Norberg, S. Bakshi, A. S. Barnes, V. E. and Chawla, R. Das, S. Gutay, L. Jones, M. Jung, A. W. and Karmarkar, S. Kondratyev, D. Liu, M. Negro, G. and Neumeister, N. Paspalaki, G. Piperov, S. Purohit, A. and Schulte, J. F. Stojanovic, M. Thieman, J. Wang, F. Xiao, R. Xie, W. Dolen, J. Parashar, N. Baty, A. Carnahan, T. Decaro, M. Dildick, S. Ecklund, K. M. Freed, S. and Gardner, P. Geurts, F. J. M. Kumar, A. Li, W. Padley, B. P. Redjimi, R. Shi, W. Stahl Leiton, A. G. Yang, S. and Zhang, L. Zhang, Y. Bodek, A. de Barbaro, P. Demina, R. and Dulemba, J. L. Fallon, C. Ferbel, T. Galanti, M. and Garcia-Bellido, A. Hindrichs, O. Khukhunaishvili, A. Ranken, E. Taus, R. Chiarito, B. Chou, J. P. Gandrakota, A. and Gershtein, Y. Halkiadakis, E. Hart, A. Heindl, M. and Karacheban, O. Laflotte, I. Lath, A. Montalvo, R. Nash, K. Osherson, M. Salur, S. Schnetzer, S. Somalwar, S. and Stone, R. Thayil, S. A. Thomas, S. Wang, H. Acharya, H. and Delannoy, A. G. Fiorendi, S. Spanier, S. Bouhali, O. and Dalchenko, M. Delgado, A. Eusebi, R. Gilmore, J. Huang, T. Kamon, T. Kim, H. Luo, S. Malhotra, S. Mueller, R. Overton, D. Rathjens, D. Safonov, A. Akchurin, N. and Damgov, J. Hegde, V. Kunori, S. Lamichhane, K. Lee, S. W. Mengke, T. Muthumuni, S. Peltola, T. Volobouev, I. and Wang, Z. Whitbeck, A. Appelt, E. Greene, S. Gurrola, A. Johns, W. Melo, A. Ni, H. Padeken, K. Romeo, F. and Sheldon, P. Tuo, S. Velkovska, J. Arenton, M. W. and Cox, B. Cummings, G. Hakala, J. Hirosky, R. Joyce, M. and Ledovskoy, A. Li, A. Neu, C. Perez Lara, C. E. and Tannenwald, B. White, S. Wolfe, E. Poudyal, N. Black, K. and Bose, T. Caillol, C. Dasu, S. De Bruyn, I. and Everaerts, P. Fienga, F. Galloni, C. He, H. Herndon, M. and Herve, A. Hussain, U. Lanaro, A. Loeliger, A. and Loveless, R. Madhusudanan Sreekala, J. Mallampalli, A. and Mohammadi, A. Pinna, D. Savin, A. Shang, V. Sharma, V. and Smith, W. H. Teague, D. Trembath-Reichert, S. Vetens, W. and CMS Collaboration
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High Energy Physics::Phenomenology ,High Energy Physics::Experiment - Abstract
A measurement of the inclusive jet production in proton-proton collisions at the LHC at root s = 13TeV is presented. The double-differential cross sections are measured as a function of the jet transverse momentum p(T) and the absolute jet rapidity vertical bar y vertical bar. The anti- k(T) clustering algorithm is used with distance parameter of 0.4 (0.7) in a phase space region with jet p(T) from 97 GeV up to 3.1TeV and vertical bar y vertical bar < 2.0. Data collected with the CMS detector are used, corresponding to an integrated luminosity of 36.3 fb(-1) (33.5 fb(-1)). The measurement is used in a comprehensive QCD analysis at next-to-next-to-leading order, which results in significant improvement in the accuracy of the parton distributions in the proton. Simultaneously, the value of the strong coupling constant at the Z boson mass is extracted as alpha(S)(m(Z)) = 0.1170 +/- 0.0019. For the first time, these data are used in a standard model effective field theory analysis at next-to-leading order, where parton distributions and the QCD parameters are extracted simultaneously with imposed constraints on the Wilson coefficient c(1) of 4-quark contact interactions.
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- 2022
242. International comparability of reference unit costs of education services: when harmonizing methodology is not enough (PECUNIA project)
- Author
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I. Pokhilenko, T. Kast, L.M.M. Janssen, S.M.A.A Evers, A.T.G Paulus, J. Simon, S. Mayer, M. Berger, A. Konnopka, L. Muntendorf, V. Brodszky, L. García-Pérez, A. Park, L. Salvador-Carulla, R.M.W.A. Drost, RS: CAPHRI - R2 - Creating Value-Based Health Care, and Health Services Research
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HB Economic Theory ,Health Policy ,RA0421 Public health. Hygiene. Preventive Medicine ,Pharmacology (medical) ,General Medicine - Abstract
BACKGROUND: Health problems can lead to costs in the education sector. However, these costs are rarely incorporated in health economic evaluations due to the lack of reference unit costs (RUCs), cost per unit of service, of education services and of validated methods to obtain them. In this study, a standardized unit cost calculation tool developed in the PECUNIA project, the PECUNIA RUC Template for services, was applied to calculate the RUCs of selected education services in five European countries.METHODS: The RUCs of special education services and of educational therapy were calculated using the information collected via an exploratory gray literature search and contact with service providers.RESULTS: The RUCs of special education services ranged from €55 to €189 per school day. The RUCs of educational therapy ranged from €6 to €25 per contact and from €5 to €35 per day. Variation was observed in the type of input data and measurement unit, among other.DISCUSSION: The tool helped reduce variability in the RUCs related to costing methodology and gain insights into other aspects that contribute to the variability (e.g. data availability). Further research and efforts to generate high quality input data are required to reduce the variability of the RUCs.
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- 2022
- Full Text
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243. Search for Wγ resonances in proton-proton collisions at s=13 TeV using hadronic decays of Lorentz-boosted W bosons
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Tumasyan, A. Adam, W. Andrejkovic, J.W. Bergauer, T. Chatterjee, S. Dragicevic, M. Escalante Del Valle, A. Frühwirth, R. Jeitler, M. Krammer, N. Lechner, L. Liko, D. Mikulec, I. Pitters, F.M. Schieck, J. Schöfbeck, R. Spanring, M. Templ, S. Waltenberger, W. Wulz, C.-E. Chekhovsky, V. Litomin, A. Makarenko, V. Darwish, M.R. De Wolf, E.A. Janssen, X. Kello, T. Lelek, A. Rejeb Sfar, H. Van Mechelen, P. Van Putte, S. Van Remortel, N. Blekman, F. Bols, E.S. D'Hondt, J. De Clercq, J. Delcourt, M. Lowette, S. Moortgat, S. Morton, A. Müller, D. Sahasransu, A.R. Tavernier, S. Van Doninck, W. Van Mulders, P. Beghin, D. Bilin, B. Clerbaux, B. De Lentdecker, G. Favart, L. Grebenyuk, A. Kalsi, A.K. Lee, K. Mahdavikhorrami, M. Makarenko, I. Moureaux, L. Pétré, L. Popov, A. Postiau, N. Starling, E. Thomas, L. Vanden Bemden, M. Vander Velde, C. Vanlaer, P. Vannerom, D. Wezenbeek, L. Cornelis, T. Dobur, D. Gruchala, M. Mestdach, G. Niedziela, M. Roskas, C. Skovpen, K. Tytgat, M. Verbeke, W. Vermassen, B. Vit, M. Bethani, A. Bruno, G. Bury, F. Caputo, C. David, P. Delaere, C. Donertas, I.S. Giammanco, A. Lemaitre, V. Mondal, K. Prisciandaro, J. Taliercio, A. Teklishyn, M. Vischia, P. Wertz, S. Wuyckens, S. Alves, G.A. Hensel, C. Moraes, A. Aldá Júnior, W.L. Barroso Ferreira Filho, M. Brandao Malbouisson, H. Carvalho, W. Chinellato, J. Da Costa, E.M. Da Silveira, G.G. De Jesus Damiao, D. Fonseca De Souza, S. Matos Figueiredo, D. Mora Herrera, C. Mota Amarilo, K. Mundim, L. Nogima, H. Rebello Teles, P. Sanchez Rosas, L.J. Santoro, A. Silva Do Amaral, S.M. Sznajder, A. Thiel, M. Torres Da Silva De Araujo, F. Vilela Pereira, A. Bernardes, C.A. Calligaris, L. Fernandez Perez Tomei, T.R. Gregores, E.M. Lemos, D.S. Mercadante, P.G. Novaes, S.F. Padula, S.S. Aleksandrov, A. Antchev, G. Atanasov, I. Hadjiiska, R. Iaydjiev, P. Misheva, M. Rodozov, M. Shopova, M. Sultanov, G. Dimitrov, A. Ivanov, T. Litov, L. Pavlov, B. Petkov, P. Petrov, A. Cheng, T. Fang, W. Guo, Q. Javaid, T. 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Thayil, S.A. Thomas, S. Acharya, H. Delannoy, A.G. Spanier, S. Bouhali, O. Dalchenko, M. Delgado, A. Eusebi, R. Gilmore, J. Huang, T. Kamon, T. Luo, S. Malhotra, S. Mueller, R. Overton, D. Rathjens, D. Safonov, A. Akchurin, N. Damgov, J. Hegde, V. Kunori, S. Lamichhane, K. Mengke, T. Muthumuni, S. Peltola, T. Undleeb, S. Volobouev, I. Whitbeck, A. Appelt, E. Greene, S. Gurrola, A. Johns, W. Maguire, C. Melo, A. Ni, H. Padeken, K. Romeo, F. Sheldon, P. Tuo, S. Velkovska, J. Arenton, M.W. Cox, B. Cummings, G. Hakala, J. Hirosky, R. Joyce, M. Ledovskoy, A. Li, A. Neu, C. Tannenwald, B. Wolfe, E. Karchin, P.E. Poudyal, N. Thapa, P. Black, K. Bose, T. Buchanan, J. Caillol, C. Dasu, S. De Bruyn, I. Everaerts, P. Fienga, F. Galloni, C. He, H. Herndon, M. Hervé, A. Hussain, U. Lanaro, A. Loeliger, A. Loveless, R. Madhusudanan Sreekala, J. Mallampalli, A. Mohammadi, A. Pinna, D. Savin, A. Shang, V. Smith, W.H. Teague, D. Trembath-reichert, S. Vetens, W. The CMS Collaboration
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High Energy Physics::Experiment - Abstract
A search for Wγ resonances in the mass range between 0.7 and 6.0 TeV is presented. The W boson is reconstructed via its hadronic decays, with the final-state products forming a single large-radius jet, owing to a high Lorentz boost of the W boson. The search is based on proton-proton collision data at s=13 TeV, corresponding to an integrated luminosity of 137 fb−1, collected with the CMS detector at the LHC in 2016–2018. The Wγ mass spectrum is parameterized with a smoothly falling background function and examined for the presence of resonance-like signals. No significant excess above the predicted background is observed. Model-specific upper limits at 95% confidence level on the product of the cross section and branching fraction to the Wγ channel are set. Limits for narrow resonances and for resonances with an intrinsic width equal to 5% of their mass, for spin-0 and spin-1 hypotheses, range between 0.17 fb at 6.0 TeV and 55 fb at 0.7 TeV. These are the most restrictive limits to date on the existence of such resonances over a large range of probed masses. In specific heavy scalar (vector) triplet benchmark models, narrow resonances with masses between 0.75 (1.15) and 1.40 (1.36) TeV are excluded for a range of model parameters. Model-independent limits on the product of the cross section, signal acceptance, and branching fraction to the Wγ channel are set for minimum Wγ mass thresholds between 1.5 and 8.0 TeV. © 2022 The Author(s)
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- 2022
244. Measurement of W±γ differential cross sections in proton-proton collisions at s =13 TeV and effective field theory constraints
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Ni, H. Padeken, K. Romeo, F. Sheldon, P. Tuo, S. Velkovska, J. Arenton, M.W. Cox, B. Cummings, G. Hakala, J. Hirosky, R. Joyce, M. Ledovskoy, A. Li, A. Neu, C. Tannenwald, B. White, S. Wolfe, E. Poudyal, N. Black, K. Bose, T. Buchanan, J. Caillol, C. Dasu, S. De Bruyn, I. Everaerts, P. Fienga, F. Galloni, C. He, H. Herndon, M. Hervé, A. Hussain, U. Lanaro, A. Loeliger, A. Loveless, R. Madhusudanan Sreekala, J. Mallampalli, A. Mohammadi, A. Pinna, D. Savin, A. Shang, V. Sharma, V. Smith, W.H. Teague, D. Trembath-Reichert, S. Vetens, W. (CMS Collaboration)
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High Energy Physics::Experiment ,Nuclear Experiment - Abstract
Differential cross section measurements of W±γ production in proton-proton collisions at s=13 TeV are presented. The data set used in this study was collected with the CMS detector at the CERN LHC in 2016-2018 with an integrated luminosity of 138 fb-1. Candidate events containing an electron or muon, a photon, and missing transverse momentum are selected. The measurements are compared with standard model predictions computed at next-to-leading and next-to-next-to-leading orders in perturbative quantum chromodynamics. Constraints on the presence of TeV-scale new physics affecting the WWγ vertex are determined within an effective field theory framework, focusing on the O3W operator. A simultaneous measurement of the photon transverse momentum and the azimuthal angle of the charged lepton in a special reference frame is performed. This two-dimensional approach provides up to a factor of ten more sensitivity to the interference between the standard model and the O3W contribution than using the transverse momentum alone. © 2022 CERN.
- Published
- 2022
245. Cardiac troponins and adverse outcomes in European patients with atrial fibrillation: A report from the ESC-EHRA EORP atrial fibrillation general long-term registry
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Marco Vitolo, Vincenzo L. Malavasi, Marco Proietti, Igor Diemberger, Laurent Fauchier, Francisco Marin, Michael Nabauer, Tatjana S. Potpara, Gheorghe-Andrei Dan, Zbigniew Kalarus, Luigi Tavazzi, Aldo Pietro Maggioni, Deirdre A. Lane, Gregory Y.H. Lip, Giuseppe Boriani, G. Boriani, G.Y.H. Lip, L. Tavazzi, A.P. Maggioni, G-A. Dan, T. Potpara, M. Nabauer, F. Marin, Z. Kalarus, L. Fauchier, A. Goda, G. Mairesse, T. Shalganov, L. Antoniades, M. Taborsky, S. Riahi, P. Muda, I. García Bolao, O. Piot, K. Etsadashvili, M. Haim, A. Azhari, J. Najafian, M. Santini, E. Mirrakhimov, K. Kulzida, A. Erglis, L. Poposka, M.R. Burg, H. Crijns, Ö. Erküner, D. Atar, R. Lenarczyk, M. Martins Oliveira, D. Shah, E. Serdechnaya, E. Diker, E. Zëra, U. Ekmekçiu, V. Paparisto, M. Tase, H. Gjergo, J. Dragoti, M. Ciutea, N. Ahadi, Z. el Husseini, M. Raepers, J. Leroy, P. Haushan, A. Jourdan, C. Lepiece, L. Desteghe, J. Vijgen, P. Koopman, G. Van Genechten, H. Heidbuchel, T. Boussy, M. De Coninck, H. 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Szwed, A. Musialik-Lydka, A. Leopold-Jadczyk, E. Jedrzejczyk-Patej, M. Koziel, M. Mazurek, K. Krzemien-Wolska, P. Starosta, E. Nowalany-Kozielska, A. Orzechowska, M. Szpot, M. Staszel, S. Almeida, H. Pereira, L. Brandão Alves, R. Miranda, L. Ribeiro, F. Costa, F. Morgado, P. Carmo, P. Galvao Santos, R. Bernardo, P. Adragão, G. Ferreira da Silva, M. Peres, M. Alves, M. Leal, A. Cordeiro, P. Magalhães, P. Fontes, S. Leão, A. Delgado, A. Costa, B. Marmelo, B. Rodrigues, D. Moreira, J. Santos, L. Santos, A. Terchet, D. Darabantiu, S. Mercea, V. Turcin Halka, A. Pop Moldovan, A. Gabor, B. Doka, G. Catanescu, H. Rus, L. Oboroceanu, E. Bobescu, R. Popescu, A. Dan, A. Buzea, I. Daha, G. Dan, I. Neuhoff, M. Baluta, R. Ploesteanu, N. Dumitrache, M. Vintila, A. Daraban, C. Japie, E. Badila, H. Tewelde, M. Hostiuc, S. Frunza, E. Tintea, D. Bartos, A. Ciobanu, I. Popescu, N. Toma, C. Gherghinescu, D. Cretu, N. Patrascu, C. Stoicescu, C. Udroiu, G. Bicescu, V. Vintila, D. Vinereanu, M. Cinteza, R. Rimbas, M. Grecu, A. Cozma, F. Boros, M. Ille, O. Tica, R. Tor, A. Corina, A. Jeewooth, B. Maria, C. Georgiana, C. Natalia, D. Alin, D. Dinu-Andrei, M. Livia, R. Daniela, R. Larisa, S. Umaar, T. Tamara, M. Ioachim Popescu, D. Nistor, I. Sus, O. Coborosanu, N. Alina-Ramona, R. Dan, L. Petrescu, G. Ionescu, C. Vacarescu, E. Goanta, M. Mangea, A. Ionac, C. Mornos, D. Cozma, S. Pescariu, E. Solodovnicova, I. Soldatova, J. Shutova, L. Tjuleneva, T. Zubova, V. Uskov, D. Obukhov, G. Rusanova, N. Isakova, S. Odinsova, T. Arhipova, E. Kazakevich, O. Zavyalova, T. Novikova, I. Riabaia, S. Zhigalov, E. Drozdova, I. Luchkina, Y. Monogarova, D. Hegya, L. Rodionova, V. Nevzorova, O. Lusanova, A. Arandjelovic, D. Toncev, L. Vukmirovic, M. Radisavljevic, M. Milanov, N. Sekularac, M. Zdravkovic, S. Hinic, S. Dimkovic, T. Acimovic, J. Saric, S. Radovanovic, A. Kocijancic, B. Obrenovic-Kircanski, D. Kalimanovska Ostric, D. Simic, I. Jovanovic, I. Petrovic, M. Polovina, M. Vukicevic, M. Tomasevic, N. Mujovic, N. Radivojevic, O. Petrovic, S. Aleksandric, V. Kovacevic, Z. Mijatovic, B. Ivanovic, M. Tesic, A. Ristic, B. Vujisic-Tesic, M. Nedeljkovic, A. Karadzic, A. Uscumlic, M. Prodanovic, M. Zlatar, M. Asanin, B. Bisenic, V. Vasic, Z. Popovic, D. Djikic, M. Sipic, V. Peric, B. Dejanovic, N. Milosevic, S. Backovic, A. Stevanovic, A. Andric, B. Pencic, M. Pavlovic-Kleut, V. Celic, M. Pavlovic, M. Petrovic, M. Vuleta, N. Petrovic, S. Simovic, Z. Savovic, S. Milanov, G. Davidovic, V. Iric-Cupic, D. Djordjevic, M. Damjanovic, S. Zdravkovic, V. Topic, D. Stanojevic, M. Randjelovic, R. Jankovic-Tomasevic, V. Atanaskovic, S. Antic, D. Simonovic, M. Stojanovic, S. Stojanovic, V. Mitic, V. Ilic, D. Petrovic, M. Deljanin Ilic, S. Ilic, V. Stoickov, S. Markovic, A. Mijatovic, D. Tanasic, G. Radakovic, J. Peranovic, N. Panic-Jelic, O. Vujadinovic, P. Pajic, S. Bekic, S. Kovacevic, A. García Fernandez, A. Perez Cabeza, M. Anguita, L. Tercedor Sanchez, E. Mau, J. Loayssa, M. Ayarra, M. Carpintero, I. Roldán Rabadan, M. Gil Ortega, A. Tello Montoliu, E. Orenes Piñero, S. Manzano Fernández, F. Marín, A. Romero Aniorte, A. Veliz Martínez, M. Quintana Giner, G. Ballesteros, M. Palacio, O. Alcalde, I. García-Bolao, V. Bertomeu Gonzalez, F. Otero-Raviña, J. García Seara, J. Gonzalez Juanatey, N. Dayal, P. Maziarski, P. Gentil-Baron, M. Koç, E. Onrat, I.E. Dural, K. Yilmaz, B. Özin, S. Tan Kurklu, Y. Atmaca, U. Canpolat, L. Tokgozoglu, A.K. Dolu, B. Demirtas, D. Sahin, O. Ozcan Celebi, G. Gagirci, U.O. Turk, H. Ari, N. Polat, N. Toprak, M. Sucu, O. Akin Serdar, A. Taha Alper, A. Kepez, Y. Yuksel, A. Uzunselvi, S. Yuksel, M. Sahin, O. Kayapinar, T. Ozcan, H. Kaya, M.B. Yilmaz, M. Kutlu, M. Demir, C. Gibbs, S. Kaminskiene, M. Bryce, A. Skinner, G. Belcher, J. Hunt, L. Stancombe, B. Holbrook, C. Peters, S. Tettersell, A. Shantsila, D. Lane, K. Senoo, M. Proietti, K. Russell, P. Domingos, S. Hussain, J. Partridge, R. Haynes, S. Bahadur, R. Brown, S. McMahon, J. McDonald, K. Balachandran, R. Singh, S. Garg, H. Desai, K. Davies, W. Goddard, G. Galasko, I. Rahman, Y. Chua, O. Payne, S. Preston, O. Brennan, L. Pedley, C. Whiteside, C. Dickinson, J. Brown, K. Jones, L. Benham, R. Brady, L. Buchanan, A. Ashton, H. Crowther, H. Fairlamb, S. Thornthwaite, C. Relph, A. McSkeane, U. Poultney, N. Kelsall, P. Rice, T. Wilson, M. Wrigley, R. Kaba, T. Patel, E. Young, J. Law, C. Runnett, H. Thomas, H. McKie, J. Fuller, S. Pick, A. Sharp, A. Hunt, K. Thorpe, C. Hardman, E. Cusack, L. Adams, M. Hough, S. Keenan, A. Bowring, J. Watts, J. Zaman, K. Goffin, H. Nutt, Y. Beerachee, J. Featherstone, C. Mills, J. Pearson, L. Stephenson, S. Grant, A. Wilson, C. Hawksworth, I. Alam, M. Robinson, S. Ryan, R. Egdell, E. Gibson, M. Holland, D. Leonard, B. Mishra, S. Ahmad, H. Randall, J. Hill, L. Reid, M. George, S. McKinley, L. Brockway, W. Milligan, J. Sobolewska, J. Muir, L. Tuckis, L. Winstanley, P. Jacob, S. Kaye, L. Morby, A. Jan, T. Sewell, C. Boos, B. Wadams, C. Cope, P. Jefferey, N. Andrews, A. Getty, A. Suttling, C. Turner, K. Hudson, R. Austin, S. Howe, R. Iqbal, N. Gandhi, K. Brophy, P. Mirza, E. Willard, S. Collins, N. Ndlovu, E. Subkovas, V. Karthikeyan, L. Waggett, A. Wood, A. Bolger, J. Stockport, L. Evans, E. Harman, J. Starling, L. Williams, V. Saul, M. Sinha, L. Bell, S. Tudgay, S. Kemp, L. Frost, T. Ingram, A. Loughlin, C. Adams, M. Adams, F. Hurford, C. Owen, C. Miller, D. Donaldson, H. Tivenan, H. Button, A. Nasser, O. Jhagra, B. Stidolph, C. Brown, C. Livingstone, M. Duffy, P. Madgwick, P. Roberts, E. Greenwood, L. Fletcher, M. Beveridge, S. Earles, D. McKenzie, D. Beacock, M. Dayer, M. Seddon, D. Greenwell, F. Luxton, F. Venn, H. Mills, J. Rewbury, K. James, K. Roberts, L. Tonks, D. Felmeden, W. Taggu, A. Summerhayes, D. Hughes, J. Sutton, L. Felmeden, M. Khan, E. Walker, L. Norris, L. O'Donohoe, A. Mozid, H. Dymond, H. Lloyd-Jones, G. Saunders, D. Simmons, D. Coles, D. Cotterill, S. Beech, S. Kidd, B. Wrigley, S. Petkar, A. Smallwood, R. Jones, E. Radford, S. Milgate, S. Metherell, V. Cottam, C. Buckley, A. Broadley, D. Wood, J. Allison, K. Rennie, L. Balian, L. Howard, L. Pippard, S. Board, and T. Pitt-Kerby
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Male ,AF registry ,Atrial fibrillation ,Biomarkers ,Death ,Major adverse cardiovascular events ,outcomes ,Troponins ,Troponin ,Risk Factors ,Atrial Fibrillation ,Internal Medicine ,Humans ,Female ,Prospective Studies ,Registries ,Aged - Abstract
BACKGROUND: Cardiac troponins (cTn) have been reported to be predictors for adverse outcomes in atrial fibrillation (AF), patients, but their actual use is still unclear.AIM: To assess the factors associated with cTn testing in routine practice and evaluate the association with outcomes.METHODS: Patients enrolled in the ESC-EHRA EORP-AF General Long-Term Registry were stratified into 3 groups according to cTn levels as (i) cTn not tested, (ii) cTn in range (≤99th percentile), (iii) cTn elevated (>99th percentile). The composite outcome of any thromboembolism /any acute coronary syndrome/cardiovascular (CV) death, defined as Major Adverse Cardiovascular Events (MACE) and all-cause death were the main endpoints.RESULTS: Among 10 445 AF patients (median age 71 years, 40.3% females) cTn were tested in 2834 (27.1%). cTn was elevated in 904/2834 (31.9%) and in-range in 1930/2834 (68.1%) patients. Female sex, in-hospital enrollment, first-detected AF, CV risk factors, history of coronary artery disease, and atypical AF symptoms were independently associated with cTn testing. Elevated cTn were independently associated with a higher risk for MACE (Model 1, hazard ratio [HR] 1.74, 95% confidence interval [CI] 1.40-2.16, Model 2, HR 1.62, 95% CI 1.28-2.05; Model 3 HR 1.76, 95% CI 1.37-2.26) and all-cause death (Model 1, HR 1.45, 95% CI 1.21-1.74; Model 2, HR 1.36, 95% CI 1.12-1.66; Model 3, HR 1.38, 95% CI 1.12-1.71).CONCLUSIONS: Elevated cTn levels were associated with an increased risk of all-cause mortality and adverse CV events. Clinical factors that might enhance the need to rule out CAD were associated with cTn testing.
- Published
- 2022
246. Evidence for X(3872) in Pb-Pb Collisions and Studies of its Prompt Production at root s(NN)=5.02 TeV
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- Subjects
High Energy Physics::Experiment - Abstract
The first evidence for X(3872) production in relativistic heavy ion collisions is reported. The X(3872) production is studied in lead-lead (Pb-Pb) collisions at a center-of-mass energy of root s(NN) = 5.02 TeV per nucleon pair, using the decay chain X(3872) -> J/psi pi(+)pi(-) -> mu(+) mu(-) pi(+)pi(-). The data were recorded with the CMS detector in 2018 and correspond to an integrated luminosity of 1.7 nb(-1). The measurement is performed in the rapidity and transverse momentum ranges vertical bar y vertical bar < 1.6 and 15 < p(T) < 50 GeV/c. The significance of the inclusive X(3872) signal is 4.2 standard deviations. The prompt X(3872) to psi 2S yield ratio is found to be rho(Pb-Pb) = 1.08 +/- 0.49(stat) +/- 0.52(syst), to be compared with typical values of 0.1 for pp collisions. This result provides a unique experimental input to theoretical models of the X(3872) production mechanism, and of the nature of this exotic state.
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- 2022
247. Biochemical methods to monitor loading and activation of hexameric helicases
- Author
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Amy J. Fernandez and James M. Berger
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- 2022
248. Measurement of double-parton scattering in inclusive production of four jets with low transverse momentum in proton-proton collisions at root s=13 TeV
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Savin, A. Shang, V Smith, W. H. Teague, D. Trembath-reichert, S. Vetens, W. CMS Collaboration
- Subjects
Astrophysics::High Energy Astrophysical Phenomena ,High Energy Physics::Phenomenology ,High Energy Physics::Experiment ,Nuclear Experiment - Abstract
A measurement of inclusive four-jet production in proton-proton collisions at a center-of-mass energy of 13 TeV is presented. The transverse momenta of jets within vertical bar eta vertical bar 4.7 are required to exceed 35, 30, 25, and 20 GeV for the first-, second-, third-, and fourth-leading jet, respectively. Differential cross sections are measured as functions of the jet transverse momentum, jet pseudorapidity, and several other observables that describe the angular correlations between the jets. The measured distributions show sensitivity to different aspects of the underlying event, parton shower modeling, and matrix element calculations. In particular, the interplay between angular correlations caused by parton shower and double-parton scattering contributions is shown to be important. The double-parton scattering contribution is extracted by means of a template fit to the data, using distributions for single-parton scattering obtained from Monte Carlo event generators and a double-parton scattering distribution constructed from inclusive single-jet events in data. The effective double-parton scattering cross section is calculated and discussed in view of previous measurements and of its dependence on the models used to describe the single-parton scattering background.
- Published
- 2022
249. Study of quark and gluon jet substructure in Z plus jet and dijet events from pp collisions
- Author
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Gershtein, Y. and Halkiadakis, E. Hart, A. Heindl, M. Karacheban, O. and Laflotte, I Lath, A. Montalvo, R. Nash, K. Osherson, M. and Salur, S. Schnetzer, S. Somalwar, S. Stone, R. and Thayil, S. A. Thomas, S. Acharya, H. Delannoy, A. G. and Fiorendi, S. Spanier, S. Bouhali, O. Dalchenko, M. and Delgado, A. Eusebi, R. Gilmore, J. Huang, T. Luo, S. and Malhotra, S. Mueller, R. Overton, D. Rathjens, D. and Safonov, A. Akchurin, N. Damgov, J. Hegde, V Kunori, S. and Lamichhane, K. Mengke, T. Muthumuni, S. Peltola, T. and Volobouev, I Whitbeck, A. Appelt, E. Greene, S. Gurrola, A. Johns, W. Melo, A. Ni, H. Padeken, K. Romeo, F. and Sheldon, P. Tuo, S. Velkovska, J. Arenton, M. W. and Cox, B. Cummings, G. Hakala, J. Hirosky, R. Joyce, M. and Ledovskoy, A. Li, A. Neu, C. Tannenwald, B. White, S. Wolfe, E. Poudyal, N. Black, K. Bose, T. Caillol, C. Dasu, S. De Bruyn, I Everaerts, P. Fienga, F. and Galloni, C. He, H. Herndon, M. Herve, A. Hussain, U. and Lanaro, A. Loeliger, A. Loveless, R. Sreekala, J. Madhusudanan Mallampalli, A. Mohammadi, A. Pinna, D. and Savin, A. Shang, V Smith, W. H. Teague, D. and Trembath-reichert, S. Vetens, W. CMS Collaboration
- Subjects
Astrophysics::High Energy Astrophysical Phenomena ,High Energy Physics::Phenomenology ,High Energy Physics::Experiment ,Nuclear Experiment - Abstract
Measurements of jet substructure describing the composition of quark- and gluon-initiated jets are presented. Proton-proton (pp) collision data at root s = 13 TeV collected with the CMS detector are used, corresponding to an integrated luminosity of 35.9 fb(-1). Generalized angularities are measured that characterize the jet substructure and distinguish quark- and gluon-initiated jets. These observables are sensitive to the distributions of transverse momenta and angular distances within a jet. The analysis is performed using a data sample of dijet events enriched in gluon-initiated jets, and, for the first time, a Z+jet event sample enriched in quark-initiated jets. The observables are measured in bins of jet transverse momentum, and as a function of the jet radius parameter. Each measurement is repeated applying a “soft drop” grooming procedure that removes soft and large angle radiation from the jet. Using these measurements, the ability of various models to describe jet substructure is assessed, showing a clear need for improvements in Monte Carlo generators.
- Published
- 2022
250. Nutrition: The Very Old Critically Ill Patients
- Author
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Mette M. Berger, Claire Anne Hurni, and Olivier Pantet
- Published
- 2022
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