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Antecedentes: la cuenca del río Porce‚ en la que se localizan los embalses Porce II y Porce III‚ alberga una ictiofauna nativa‚ cuyas especies carecen en su mayoría de descripción anatómica. El Chaetostoma thomsoni es un pez teleósteo del orden Siluriformes de la familia Loricariidae‚ que suele ser abundante en los ecosistemas fluviales del Magdalena y normalmente se encuentra en el cauce de ríos y quebradas de corriente rápida con pendientes moderadas. Objetivo: realizar la descripción anatómica e histológica de Chaetostoma thomsoni del río Porce. Métodos: se capturaron 15 ejemplares en quebradas con electropesca o atarraya (Aval de comité ética Acta número 138 del 9 de febrero del 2021) Los ejemplares fueron sumergidos en solución de eugenol (100 mg/L) como eutanásico y fijado en solución de formol tamponado al 10 %‚ separados en tubos tipo Falcon y etiquetados con serial e información biológica. Posteriormente‚ se trasladaron al Laboratorio de Anatomía Animal de la Universidad de Antioquia - UdeA para realizar su disección y obtener medidas biométricas se utilizaron los siguientes materiales: equipo de disección e instrumental entomológico‚ cinta métrica‚ pie de rey y balanza. Resultados: se obtuvo un estudio morfométrico completo de la anatomía externa y mediante disección de los ejemplares‚ una detallada descripción de su anatomía interna. También se identificaron las diferentes estructuras macroscópicas y microscópicas de los principales órganos y sistemas‚ como la forma en espiral del intestino y la longitud total del mismo. Mediante la lectura de placas histológicas se determinaron algunas particularidades como la presencia de hepatopáncreas‚ así como la disposición de la piel y sus anexos. Conclusiones: la descripción anatómica detallada proporciona valiosa información sobre la salud de los animales y aspectos de anatomía aplicada como el conocimiento del sitio de venopunción adecuado para la toma de muestras. La realización de esta descripción anatómica es fundamental para futuras investigaciones que ayudarán a recabar información que propenda por la protección de la ictiofauna nativa; y sentar las bases para estudios fisiológicos futuros. [ABSTRACT FROM AUTHOR]

Don Santiago Ramón y Cajal, fue un médico científico y artista español, que fascino al mundo con sus investigaciones sobre el sistema nervioso. En este artículo se presenta una breve biografía de su vida, desde su niñez hasta su muerte; sobre como impacto su padre en su vida y de cómo su tenacidad lo llevó a ser galardonado con el premio más importante para un científico, el premio Nobel.

Copyright of Compendium of Veterinary Sciences / Compendio de Ciencias Veterinarias is the property of Facultad de Ciencias Veterinarias de la Universidad Nacional de Asuncion and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

O objetivo deste trabalho foi analisar a morfologia dos testículos de tuviras machos (Gymnotus spp.) submetidas à reprodução por diferentes indutores hormonais. Foram utilizadas quarenta tuviras macho de aproximadamente 40 g em um delineamento inteiramente casualizado, com quatro tratamentos e 10 repetições, sendo que cada animal foi considerado uma repetição. Para estabelecimento do protocolo hormonal foram testados três indutores: extrato bruto de hipófise de carpa (EBHC), gonadotrofina coriônica equina (ECG), análogo sintético do hormônio liberador de gonadotrofina (GnRH-a) e no grupo controle foi administrada solução salina a 2%. Os três hormônios e o controle foram aplicados em duas dosagens (preparatória e indução final). Após 12 horas da segunda aplicação, cinco machos de cada tratamento foram eutanasiados para avaliação macroscópica e microscópica. Foi determinada a proporção volumétrica ocupada pelos componentes do parênquima testicular (túbulos seminíferos e tecido intertubular) e quantificadas as populações de espermatogônias do tipo A, do tipo B, espermatócitos primários, espermatócitos secundários, espermátides, células de Sertoli (S) e proporção de Lúmen. Os resultados indicaram que o hormônio GnRH-a apresentou uma maior capacidade para promover a maturação final nos testículos, seguido pelo hormônio eCG. O hormônio EBHC não conseguiu promover a maturação final nas tuviras induzidas.

Realizou-se este trabalho com o objetivo de avaliar o quitooligossacarídeo (QOS) frente a dois antibióticos utilizados como promotores de crescimento, a colistina e lincomicina, quanto ao desempenho, frequência de diarreia, características viscerais, morfometria e imunoglobulinas séricas, IgA, IgG e IgM. Foram utilizados 96 leitões de genética Pen Ar Lan®, desmamados com idade média de 17 dias e peso de 5,33 ± 0,369 kg para avaliação de desempenho e imunoglobulinas séricas. Para a avaliação histológica e peso dos órgãos, foram utilizados 24 animais com idade de 35 dias e peso de 6,86 ± 0,64 kg. Os três tratamentos consistiram em uma dieta basal acrescida de QOS (100 mg Kg -1), dieta basal com colistina 40 mg Kg -1 e dieta basal com lincomicina 4,4 mg Kg -1. Para o desempenho, os antibióticos apresentaram melhor ganho diário de peso (GPD) dos 49 aos 63 dias de idade em relação ao QOS e a conversão alimentar (CA) foi melhor para a colistina em comparação com os demais tratamentos, além disso apresentou menor incidência de diarreia aquosa quando comparada com os outros tratamentos. Para as vísceras, observou-se aumento do peso relativo do baço, maior comprimento do intestino delgado e menor pH duodenal para os leitões que receberam QOS em relação aos antibióticos. A morfometria indicou maior altura de vilosidades e melhor relação vilos/cripta para a colistina em relação ao QOS e menor escore lesional em relação aos demais tratamentos. A concentração sérica de imunoglobulinas apontou uma maior concentração de IgA para o QOS aos 35 dias. Frente aos resultados observados, embora o QOS tenha promovido estímulos sobre o sistema imune do animal, este não foi eficiente para substituir a colistina como promotor de crescimento para leitões desmamados com 17 dias de idade.

No ensino superior ainda prevalecem as práticas pedagógicas tradicionais, nas quais o professor ocupa o centro do processo ensino-aprendizagem e os estudantes assumem uma postura passiva na construção do conhecimento. Esta realidade tem sido discutida e várias metodologias ativas de ensino têm sido propostas nas universidades, com o objetivo de atender a uma demanda de jovens cada vez mais ligados nas tecnologias de informação e que fazem parte de uma geração com perfil diferente das gerações anteriores, denominada geração Z. A Histologia é uma disciplina do ciclo básico do Curso de Odontologia, fundamental para alicerçar as bases do conhecimento do aluno e promover o desenvolvimento cognitivo de habilidades e competências essenciais para o sucesso na sua futura profissão. Com o objetivo de motivar os nossos alunos e melhorar seu desempenho no estudo da Histologia, os docentes desta disciplina do Curso de Odontologia do Instituto de Ciência e Tecnologia (ICT-UNESP) de São José dos Campos, elaboraram uma estratégia pedagógica baseada na introdução de metodologias ativas de ensino, considerando algumas práticas docentes convencionais associadas à inserção da tecnologia na educação. Com a utilização das tecnologias de informação e comunicação (TICs), dinâmicas de grupo e estudo de casos, foi possível observar que houve uma mudança do processo ensino-aprendizagem, no qual o aluno começou a assumir o papel de protagonista na construção do seu saber, possibilitando avanços significativos na consolidação dos conhecimentos específicos da Histologia.

Introdução: As micoses subcutâneas provocadas por fungos demáceos (MSCFD)são classificadas conforme sua apresentação no tecido: cromoblastomicose com presença de corpúsculos fumagoides, feoifomicose com hifas septadas demáceas e eumicetoma com grãos compostos por hifas septadas demáceas. Diversos tratamentos são propostos, entre eles a exérese cirúrgica. O tratamento cirúrgico é mais indicado nos casos em que há infecção localizada e passível de exérese, com bons resultados terapêuticos e baixa taxa de recidiva. Objetivo: Apresentar a experiência de um serviço dermatológico no tratamento cirúrgico dos casos de MSCFD, discutindo as abordagens cirúrgicas e seus resultados. Métodos: Estudo retrospectivo com análise descritiva dos casos atendidos no período de abril de 2014 a dezembro de 2016 em clínica dermatológica da cidade de São Paulo. Foram incluídos todos os casos com diagnóstico de MSCFD que foram submetidos à terapêutica cirúrgica com exérese total da lesão. Resultados: Foram totalizados sete casos: dois de eumicetoma, um de cromoblastomicose e quatro de feoifomicose. De todos os casos apenas um não foi abordado em regime de centro cirúrgico ambulatorial. Todos evoluíram sem sequelas e sem recidivas no seguimento clínico. Conclusões: A remoção da lesão cutânea é um boa opção terapêutica nos casos de MSCFD em que o procedimento cirúrgico for viável.

Este trabajo describe la renovación pedagógico-didáctica iniciada COfl pruebas piloto y una publicación en la década del 70 y concretada entre 1986 y 2001 en la Cátedra de Histología y Embriología (Facultad de Ciencias Médicas, Universidad Nacional de Rosario). Dicho proceso, centrado en actividades diferenciales del alumno y del docente, se adaptó al ingreso masivo e irrestricto vigente en ese lapso (2000 ± 500 alumnos). El diseño incluyó manejo individual y/o grupal de ¡nódulos de autoaprendizaje y de auto-evaluación, laboratorios con entrenamiento diagnóstico microscópico mediante protocolos similares a historias clínicas, sesiones de resolución de problemas y sesiones teóricas de consulta y re-aprendizaje. ubicadas al final de las antedichas situaciones de enseñanza y aprendizaje. El aprendizaje siguió una trayectoria con apoyos decrecientes (total ó restringido ó mínimo o nulo) que permitió llegar al autoaprenclizaje, de manera sistemática, imprescindible para la educación médica continua. Su perdurabilidad y los auspiciosos resultados obtenidos a lo largo de 15 años, nos permiten presentarlo como un modelo válido y fiable para Facultades con contenidos histológicos y embriológicos desarrollados dentro de un formato tradicional o como coadyuvante al tránsito desde un currículo tradicional estratificado por asignaturas a uno renovado o innovado con distintos grados de integración.

Moina eugeniae es una de las especies de más abundante del zooplancton las lagunas de la provincia de Buenos Aires. Su importancia se debe al uso común de los cladoceranos como alimento para peces. El objetivo del presente estudio fue investigar las estructuras reproductivas a través de técnicas histológicas. Las muestras se tomaron con una red de plancton (150 μm) del lago Calderón (Buenos Aires) durante la primavera de 2006. Las muestras se anestesiaron con CO2 in situ y se fijaron con formaldehído al 4%. Las hembras partenogenéticas en diferentes etapas reproductivas fueron seleccionadas para realizar con ellas técnicas histológicas de rutina. No se identificaron machos durante nuestro estudio. Los ovarios son pares, seculares y dispuestos dorsalmente en el cuerpo. Los ovocitos son poliédricos con tres etapas diferentes de maduración: previtelogénica (cromatina nuclear densa), vitelogénica (abundante yema en el citoplasma y grandes gránulos de cromatina en el núcleo) y maduras (abundantes gotas lipídicas en el citoplasma). Muchas de las características morfológicas observadas son similares a las del género Daphnia. Se necesita más investigación para dilucidar el ciclo reproductivo de esta especie.

Introdução: Diabetes mellitus é uma doença metabólica que afeta vários órgãos-alvo, incluindo os ossos. OBJETIVO: Avaliar pelo método de esqueletonização o efeito do Diabetes mellitus tipo I (DM1) na microarquitetura de osso esponjoso. Material e Métodos: Quatorze ratos Wistar foram divididos em: Saudável (S, n=7) e Diabético (D, n=7). O DM1 foi induzido por meio de injeção endovenosa de estreptozotocina no grupo D, sendo a confirmação da condição realizada por checagem do nível glicêmico. Os animais foram sacrificados após 35 dias da indução no grupo D, juntamente com os do grupo S. As epífises femorais foram seccionadas, removidas, desmineralizadas e incluídas em parafina. Dois cortes (5 µm) foram obtidos, corados em Hematoxilina e Eosina, e analisados ao Microscópio de Luz. Foi realizada a delimitação interativa das trabéculas ósseas, seguido pelo processo de binarização utilizando threshold global, feita por dois operadores distintos. Depois, foi realizado o processo de esqueletonização para acesso às características das trabéculas e da rede de interconexão entre elas. Os parâmetros avaliados foram: Área óssea em micrômetros quadrados (B.Ar), Índice de Modelo estrutural (SMI), Dimensão Fractal (FD), Número de trabéculas (Tb.N), Número de ramos (B.N), Número total de junções (Junc.N), Média de pontos terminais (End.p), Média de extensão de cada ramo (R.Le) e Número de junções triplas (Triple.points.N). Resultados: Houve diferença significante apenas no parâmetro SMI para os diferentes operadores (p

Injection with monoiode sodium acetate (MIA) is widely used to produce osteoarthritis in various joints. The aim of this work was to describe the histological damage caused by MIA in the rat humeral joint; 0.1 mL of 0.5 mg mixture of MIA dissolved in 10 mL of physiological solution was injected into the left humeral joint of 21 Sprague-Dawley rats. As a control, the right joint of each rat was used. Euthanasia was performed at 4, 8 and 12 weeks post injection in groups of 7 rats. The samples maintained in 10% buffered formalin were descaled with EDTA for three months. For histological evaluation, paraffin inclusion was performed and 5 mm thick coronal cuts were made for subsequent staining with toluidine blue. In the healthy cartilage, a smooth surface was observed, all cells in the cartilage areas were normal. Changes in articular cartilage were observed after 4 weeks post injection, hypertrophic radial chondrocytes with high proteoglycan production. At 12 weeks post injection, a great deterioration was observed, the articular space was diminished. The surface of the cartilage was observed with fissures and cracks that reach the radial zone. The cells around these fissures have disappeared. A prominent loss of proteoglycans was observed due to weak toluidine blue staining. Joint injection with MIA produced lesions similar to OA. The great advantage of the OA induced by MIA, is the ease of its application and the rapidity in the progression of OA. [ABSTRACT FROM AUTHOR]

Histology belongs to the discipline of medical morphology. The knowledge is scattered and abstract in this discipline. It is difficult to the medical students beginner. Leading to poor effect on histology teaching. This study aimed to introduce medical students to the histology using barrier-based learning (BBL) method or traditional teaching method. We recruited 4 clinical medical classes, including two 5-years classes and two 7-years clinical medical classes, each of these classes randomly assigned to 1 of 2 groups. The control group received an introductory traditional teaching mode in histology. The experiment group received BBL method. Using final exam average scores, pass rate, excellent rates and phase tests to evaluate the teaching effect of these two teaching method. BBL teaching method is more effective than traditional teaching method, The application of BBL in histology is more easier to learning for the beginners of medical students. [ABSTRACT FROM AUTHOR]

The esophagus is a muscular tube whose function is to transport food from the mouth to the stomach and basically contain the same layers as the rest of the digestive tract. The morphological knowledge of structures involved in basic physiological processes in organisms is extremely important in the acquisition of ecological and evolutionary knowledge about species. This study produces morphological information proving the structures found in the green turtle's esophagus. The animals were dissected according to the methodology used by Wyneken, allowing analysis of external and internal morphological characteristics of the esophagus. The samples were processed for microscopic analysis by light and scanning electron microscopy. It was observed that the esophagus presents thin and conical dermal papillae facing the stomach throughout the mucosa to the gastroesophageal portion, decreasing its size at the end of its extension, covered by a thick keratin layer on keratinized pavement epithelial tissue. It is concluded that the esophagus of Chelonia mydas is covered by a layer of conical keratinized dermal papillae important to exert the mechanical and protective function of the mucosa of this organ, considering that the feeding of these animals is extremely abrasive, besides serving as protection so that the food does not return. [ABSTRACT FROM AUTHOR]

In the temperate forests of the Sierra Fria, Aguascalientes, Mexico, Taphrina caerulescens (Desm. & Mont.) Tul. was observed affecting leaves of Quercus eduardii Trel. This was the first report of the pathogen in Mexico and Central America. In addition to the typical symptom, the plant-pathogen interaction also results in the appearance of chlorotic lesions on the upper surface of some infected leaves. This was the first report of these atypical symptoms, which do not result in the formation of blisters. The main objective of this study was to describe the histopathological changes that occur in Q. eduardii leaves infected with T. caerulescens. Of the 25 species of oak present in the Sierra Fria, the disease incidence and severity was highest in Q. eduardii. For histopathological studies, sections of healthy and infected leaf tissue were fixed, dehydrated, embedded in paraffin, cut with a microtome and stained with fast green and safranin. The differences in the healthy and infected leaf sections were observed with a Leica DME microscope and a Carl Zeiss microscope. Leaf samples were also processed for scanning electron microscopy. The following changes were observed in the affected blister tissue: hyperplasia and hypertrophy of cells of the upper and lower epidermis and of the palisade layer cells; destruction of the cells of the spongy mesophyll layer, and destruction of the nucleus and other organelles of the palisade cells. The differences in the cell sizes between the infected and healthy leaf tissue were supported by morphometric and statistical analysis. No noticeable changes in the leaves which displayed atypical symptoms were observed. [ABSTRACT FROM AUTHOR]

Diet composition and the characteristics of the digestive tract of the blue sea catfish, Ariopsis guatemalensis, in a coastal lagoon in western Mexico were investigated. This species is consumed by locals and it has been used as a bioindicator of sewage pollution. This study aimed to determine if the feeding habits of this species were related to the macroscopic and microscopic morphological characteristics of the digestive tract. Specimens were captured in the Barra de Navidad Lagoon (Jalisco, Mexico) from 2011 to 2016. For every fish collected, total length (TL) was recorded and the esophagus, stomach, and intestine were extracted for histological analyses and identification of food items in their diet. The macroscopic and microscopic characteristics of the digestive tract and the stomach content analysis indicate A. guatemalensis is a carnivorous species with preference for goby fish. Crustaceans were the second most important food item and were dominated by portunid crabs and mud shrimps. The size and position of the mouth, the presence of dental plates on the vomer, palatines, premaxilla, and pharynx, and the presence of goblet cells in the digestive tract are characteristic of fishes that consume live hard-bodied prey and crush their food before it enters the esophagus. The relatively short intestine and the folds in the mucous membrane are characteristic of carnivorous fishes. [ABSTRACT FROM AUTHOR]

Copyright of Revista Médica Clínica Las Condes is the property of Editorial Sanchez y Barcelo and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Actualizaciones en Osteología is the property of Asociacion Argentina de Osteologia y Metabolismo Mineral and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Ginecología y Obstetricia de México is the property of Federacion Mexicana de Ginecologia y Obstetricia and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Background: Fibrous dysplasia and ossifying fibroma are benign pathologies that generally have no painful symptoms, are rare, and affect bone tissue. They produce aesthetic and functional alterations, which is why patients consult. Purpose: To describe the cellular disorders characteristic of fibrous dysplasia and ossifying fibroma, as well as their relationship with clinical forms and other histopathological variables that constitute a challenge for the oral pathologist and the clinician. Description of the cases: Two cases of adult patients, male and female, who attended the Stomatology and Oral Surgery Unit of the University of Cartagena in Colombia, are described. The patients shoed facial, asymptomatic, and unilateral asymmetries that compromised patients' aesthetics. Clinical, radiographic, and histological characteristics are described. Conclusion: Fibrous dysplasia and ossifying fibroma are similar benign bone disorders that require differential diagnosis in order to establish suitable and specific treatments. [ABSTRACT FROM AUTHOR]

The morphological and histological structure of the brains of Bufo gargarizans and Cynops orientalis were observed by anatomy and light microscopy. The results show that the brains of Bufo gargarizans and Cynops orientalis are divided into 5 parts which include the telencephalon, diencephalon, mesencephalon, cerebellum and medulla oblongata. The telencephalon consists of the olfactory bulb and the cerebral hemisphere. The olfactory bulb is developed that has two pairs of olfactory nerve. Bufo gargarizan has a symmetrical oval hemisphere optic lobes; Cynops orientalis only has a spherical optic lobe. The cerebellum is situated behind the optic lobe and closely connected with the myelencephalon. In this paper, the morphological and histological differences between the two species are discussed. The proportion of cerebral hemisphere is gradually increasing, which correlated with a progressive increase in the number of neuronal cell classes, and reflected in behavior complexity. [ABSTRACT FROM AUTHOR]

Orthodontically induced inflammatory root resorption (OIIRR) is a complication of dental treatment which consists of the degradation of local tissue due to an inflammatory reaction provoked by inappropriate orthodontic stimulus. The aim of the present systematic review was to assess the effectiveness of low-level laser therapy (LLLT) in reducing orthodontically induced inflammatory root resorption (OIIRR) in animal models. A systematic review was carried out in the MEDLINE, EMBASE and LILACS databases. Studies of interventions in animals were selected which analysed the effect of LLLT on OIIRR repair. The risk of bias was analysed through the 10 domains of the SYRCLE RoB tool for animal studies. Seventy-one studies were found; 27 were eliminated as duplicates and 44 titles/abstracts were analysed. Of these, 38 were excluded, and five studies were included for qualitative analysis. In 66.6% of the studies included, the authors state that LLLT was effective in the inhibition/repair of OIIRR. In histological analysis it was observed that root resorption was significantly less in animals treated with laser as compared to the control. Furthermore, LLLT accelerated cicatrization after OIIRR. Laser proved effective in reducing root resorption lacunae and shortening the inflammatory process induced by the application of orthodontic force. [ABSTRACT FROM AUTHOR]

Copyright of Revista Médica Clínica Las Condes is the property of Editorial Sanchez y Barcelo and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Brazilian Journal of Biology is the property of Instituto Internacional de Ecologia and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Revista de Ciencias Agricolas is the property of University of Narino, Faculty of Agricultural Sciences and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Revista Médica de Rosario is the property of Circulo Medico de Rosario and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Revista Médica de Rosario is the property of Circulo Medico de Rosario and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

To contribute knowledge of an important experimental model for studies on skin embryology, a study was carried out to describe the morphological events of the skin during the intrauterine life of Cavia porcellus from the 10th to the 60th day of gestation. Embryos and fetuses were dissected, and the skin of the nasal, cranial, lumbar and anal regions was processed byoptical microscopy. At 30 days the first hairs, called lanugos, were observed in the cranial region. The morphological description showed that a few days can make a great difference in development. [ABSTRACT FROM AUTHOR]

the aim of this study was to evaluate clinically and histological thetissue reactions produced by the implantation of the nylon cable tie transparent and colored in Wistar rats. Wistar male Wistar rats, aged 16 weeks, and weight between 350 and 450 grams were used. The rats were allocated in two groups of 24 animals: Group 1 - rats submitted to the implantation of the monofilament surgical nylon suture (Control Group); Group 2 - rats submitted to the implant of fragment of the transparent and colored nylon cable tie (Experimental Group). The implants of the animals of control group were performed with 5 mm of nylon suture monofilamentarbetween the carnosus and left paravertebral muscle; and 5 mm fragment were implanted in animal of experimental group of the transparent and colored nylon cable tie in the same region on opposite sides and equidistant from the spine. Eight rats from each group underwent euthanasia to perform the excisional biopsy of the implants for posterior histological examination in three moments: seventh day, 15th day and 90th day after implantation. Infection and / or inflammation evaluation was performed every 24 hours. Multifocal circumscribed lesions around the three implants were observed in 46.7% of the rats, between the first and seventh day after implantation. Acute inflammatory reaction was absent in all groups at the moments evaluated. Chronic inflammatory reaction was observed in the suture group and the clamps at all moments of evaluation except on the seventh day after the implantation in the group of transparent nylon cable tie. Mixed inflammatory reaction was observed in the suture group and the clamp bands on the seventh and 15th day. The implants of monofilament surgical nylon suture (Control Group), transparent and colored nylon cable tie (Experimental Group) showed similar macroscopic (clinical) and histological reactions in Wistar rats in a period of 90 days. [ABSTRACT FROM AUTHOR]