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772 results on '"Cho, Kyung-Ja"'

163. Synchronous second primary cancers in patients with squamous esophageal cancer: clinical features and survival outcome

Author

Lee, Jin Seo, primary, Ahn, Ji Yong, additional, Choi, Kee Don, additional, Song, Ho June, additional, Kim, Yong Hee, additional, Lee, Gin Hyug, additional, Jung, Hwoon-Yong, additional, Ryu, Jin-Sook, additional, Kim, Sung-Bae, additional, Kim, Jong Hoon, additional, Park, Seung-Il, additional, Cho, Kyung-Ja, additional, and Kim, Jin-Ho, additional

Published
2016
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164. Experience of Korean-Mongolian international joint workshops on pathology and cytopathology since 2007

Author

Choe, Gheeyoung, primary, Kang, Shin Kwang, additional, Kwon, Kun-Young, additional, Kim, Hankyeom, additional, Lee, An Hee, additional, Park, Jae-Bok, additional, Kim, Kyu-rae, additional, Hong, Sung Ran, additional, Jung, Soon-Hee, additional, Ha, Seung Yeon, additional, Ha, Changwon, additional, Noh, Mee Sook, additional, Lee, Sanghan, additional, Park, No Won, additional, Kim, Kee Hong, additional, Yong, Seok Joong, additional, Yoon, Moo Yeol, additional, Jeon, Seung Min, additional, Kang, Dae Young, additional, Kang, Chang Suk, additional, Kim, Ji Yeon, additional, Kim, Jihun, additional, Kim, Chul Hwan, additional, Kim, Han Sung, additional, Park, Yong-Koo, additional, Sohn, Kyung-Rak, additional, Sohn, Jin Hee, additional, Sung, Sun Hee, additional, Yu, Eunsil, additional, Yoo, Changyoung, additional, Lee, Kyi Beom, additional, Hyuk lee, Jae, additional, Lee, Ji Shin, additional, Cho, Kyung-Ja, additional, Jeong, Jin Sook, additional, and Hong, Eun Kyung, additional

Published
2016
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167. Survival Outcome of Intermediate-Grade Salivary Gland Carcinoma.

Author

Park, Gi Cheol, Roh, Jong-Lyel, Cho, Kyung-Ja, Jung, Yong Gi, Lee, Hyoun Wook, Kim, Tae Gyu, Choi, Seung-Ho, Nam, Soon Yuhl, and Kim, Sang Yoon

Subjects
CANCER relapse, ADENOID cystic carcinoma, CANCER, COMBINED modality therapy, PATIENT aftercare, METASTASIS, MULTIVARIATE analysis, NECK surgery, PAROTID gland tumors, POSTOPERATIVE period, SURVIVAL, SALIVARY gland tumors, TUMOR classification, TREATMENT effectiveness, PROGNOSIS, TUMOR treatment, CANCER risk factors
Abstract

Objective: Histological grade is the most important factor for defining treatment strategies and predicting prognosis for salivary gland carcinoma (SGC). We examined factors affecting long-term recurrence and survival among intermediate-grade SGC (IGSGC) patients to define optimal treatment modalities and outcomes. Methods: We reviewed the clinical and pathological data on 108 IGSGC patients who underwent definitive surgery with or without postoperative radiotherapy. We compared treatment outcomes by treatment strategies such as surgical extent for the primary tumor, neck dissection, or postoperative radiotherapy. Results: During a 103-month median follow-up, local, regional, and distant recurrences were detected in 14 (13.0%), 3 (2.8%), and 21 (19.4%) patients, respectively. The 10-year locoregional control (LRC), distant metastasis-free survival (DMFS), and overall survival (OS) rates were 83.1, 76.0, and 80.1%, respectively. Multivariate analyses identified a nonparotid primary site as an independent prognostic factor for LRC (p = 0.018). Adenoid cystic carcinoma and a positive pN classification were significantly unfavorable prognostic factors for DMFS (p = 0.025 and p = 0.030, respectively); overall advanced stage was an independent prognostic factor for OS (p = 0.020). Surgical extent, elective neck dissection, and postoperative adjuvant radiotherapy did not significantly affect treatment outcomes. Conclusion: Patients with early-stage IGSGC of parotid origin can achieve favorable treatment outcomes with conservative surgery alone. [ABSTRACT FROM AUTHOR]

Published
2018
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169. Chondrosarcoma: With Updates on Molecular Genetics

Author

Kim, Mi-Jung, Cho, Kyung-Ja, Ayala, Alberto G., and Ro, Jae Y.

Subjects
integumentary system, Article Subject, hemic and lymphatic diseases, skin and connective tissue diseases
Abstract

Chondrosarcoma (CHS) is a malignant cartilage-forming tumor and usually occurs within the medullary canal of long bones and pelvic bones. Based on the morphologic feature alone, a correct diangosis of CHS may be difficult, Therefore, correlation of radiological and clinicopathological features is mandatory in the diagnosis of CHS. The prognosis of CHS is closely related to histologic grading, however, histologic grading may be subjective with high inter-observer variability. In this paper, we present histologic grading system and clinicopathological and radiological findings of conventional CHS. Subtypes of CHSs, such as dedifferentiated, mesenchymal, and clear cell CHSs are also presented. In addition, we introduce updated cytogenetic and molecular genetic findings to expand our understanding of CHS biology. New markers of cell differentiation, proliferation, and cell signaling might offer important therapeutic and prognostic information in near future.

Published
2011
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178. 18F-FDG PET/CT vs. human papillomavirus, p16 and Epstein-Barr virus detection in cervical metastatic lymph nodes for identifying primary tumors.

Author

Cheol Park, Gi, Roh, Jong‐Lyel, Cho, Kyung‐Ja, Seung Kim, Jae, Hyeon Jin, Mi, Choi, Seung‐Ho, Yuhl Nam, Soon, and Yoon Kim, Sang

Abstract

Squamous cell carcinoma of unknown primary of the head and neck (SCCUP) is a heterogeneous disease entity that requires careful examination to locate the occult primary. We examined the diagnostic value of expression of biomarkers, such as human papillomavirus (HPV), p16 and Epstein-Barr virus (EBV), in metastatic lymph nodes vs. 18F-fluorodeoxyglucose (18F-FDG) positron emission tomography/computed tomography (PET/CT). We prospectively enrolled 54 consecutive SCCUP patients who received HPV, p16 and EBV analyses of lymph node fine-needle aspirates and 18F-FDG PET/CT scans and subsequently underwent examinations and biopsies under general anesthesia to detect primary tumors. The diagnostic performance of the biomarkers and 18F-FDG PET/CT were compared by using receiver operating characteristics (ROC) curve analyses with histopathological results for identification of primary tumors. Primary tumors were identified in 28 (51.9%) of 54 patients: the palatine tonsil in 24, base of the tongue in 1, nasopharynx in 2, and hypopharynx in 1. The sensitivity of p16 (85.7%) and accuracy of HPV (85.2%) were higher than those (42.9% and 68.5%) of 18F-FDG PET/CT ( p < 0.05). The area under the ROC curve of HPV was higher than that of 18F-FDG PET/CT (0.857 vs. 0.666, p = 0.007). The disease-free survival rates were higher in the patients with primary tumor detection or p16 nodal immunopositivity than in the other patients ( p < 0.05). The results showed that HPV and p16 detection in metastatic lymph nodes can help locate hidden primary tumors, guide definitive treatment and predict patient survival. [ABSTRACT FROM AUTHOR]

Published
2017
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191. Giant Cell Reparative Granuloma of the Temporal Bone: MR Findings with Pathologic Correlation

Author

Kim, Hyun Jeong, Lee, Ho Kyu, Suh, Dae Chul, Choi, Choong Gon, Kim, Jae Kyun, Lee, Jeong Hyun, and Cho, Kyung Ja

Subjects
Gadolinium DTPA, Male, Contrast Media, Temporal Bone, Hemorrhage, Hemosiderin, Middle Aged, Image Enhancement, Magnetic Resonance Imaging, Mastoid, Granuloma, Giant Cell, Image Processing, Computer-Assisted, Humans, Ear Canal, Head and Neck
Abstract

Summary: We report MR findings in a case of a giant cell reparative granuloma involving the temporal lobe in a middle-aged man. On MR images, most of the mass was hypointense on T1-weighted images, hypointense on T2-weighted images, and mildly enhanced on postcontrast T1-weighted images. The hypointensity on T2-weighted images corresponded to areas of hemorrhage and hemosiderin deposition on pathologic correlation.

Published
2003

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