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910 results on '"Bellgrove, Mark A."'

151. Potential role for immune-related genes in autism spectrum disorders: Evidence from genome-wide association meta-analysis of autistic traits

Author

Arenella, Martina, primary, Cadby, Gemma, additional, De Witte, Ward, additional, Jones, Rachel M, additional, Whitehouse, Andrew JO, additional, Moses, Eric K, additional, Fornito, Alex, additional, Bellgrove, Mark A, additional, Hawi, Ziarih, additional, Johnson, Beth, additional, Tiego, Jeggan, additional, Buitelaar, Jan K, additional, Kiemeney, Lambertus A, additional, Poelmans, Geert, additional, and Bralten, Janita, additional

Published
2021
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154. sj-pdf-1-aut-10.1177_13623613211019547 – Supplemental material for Potential role for immune-related genes in autism spectrum disorders: Evidence from genome-wide association meta-analysis of autistic traits

Author

Arenella, Martina, Cadby, Gemma, De Witte, Ward, Jones, Rachel M, Whitehouse, Andrew JO, Moses, Eric K, Fornito, Alex, Bellgrove, Mark A, Hawi, Ziarih, Johnson, Beth, Tiego, Jeggan, Buitelaar, Jan K, Kiemeney, Lambertus A, Poelmans, Geert, and Bralten, Janita

Subjects
FOS: Psychology, FOS: Clinical medicine, 170199 Psychology not elsewhere classified, 111799 Public Health and Health Services not elsewhere classified, FOS: Educational sciences, 110319 Psychiatry (incl. Psychotherapy), FOS: Health sciences, 130312 Special Education and Disability, Education
Abstract

Supplemental material, sj-pdf-1-aut-10.1177_13623613211019547 for Potential role for immune-related genes in autism spectrum disorders: Evidence from genome-wide association meta-analysis of autistic traits by Martina Arenella, Gemma Cadby, Ward De Witte, Rachel M Jones, Andrew JO Whitehouse, Eric K Moses, Alex Fornito, Mark A Bellgrove, Ziarih Hawi, Beth Johnson, Jeggan Tiego, Jan K Buitelaar, Lambertus A Kiemeney, Geert Poelmans and Janita Bralten in Autism

Published
2021
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155. sj-pdf-1-jad-10.1177_10870547211003671 – Supplemental material for Recent Attitudes toward ADHD in the Broader Community: A Systematic Review

Author

Bisset, Matthew, Winter, Leanne, Middeldorp, Christel M., Coghill, David, Nardia Zendarski, Bellgrove, Mark A., and Sciberras, Emma

Subjects
FOS: Psychology, 170199 Psychology not elsewhere classified, Education
Abstract

Supplemental material, sj-pdf-1-jad-10.1177_10870547211003671 for Recent Attitudes toward ADHD in the Broader Community: A Systematic Review by Matthew Bisset, Leanne Winter, Christel M. Middeldorp, David Coghill, Nardia Zendarski, Mark A. Bellgrove and Emma Sciberras in Journal of Attention Disorders

Published
2021
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156. Author Correction: Risk variants and polygenic architecture of disruptive behavior disorders in the context of attention-deficit/hyperactivity disorder (Nature Communications, (2021), 12, 1, (576), 10.1038/s41467-020-20443-2)

Author

Demontis, Ditte, Walters, Raymond K., Rajagopal, Veera M., Waldman, Irwin D., Grove, Jakob, Als, Thomas D., Dalsgaard, Søren, Ribasés, Marta, Bybjerg-Grauholm, Jonas, Bækvad-Hansen, Maria, Werge, Thomas, Nordentoft, Merete, Mors, Ole, Mortensen, Preben Bo, Andreassen, Ole A., Arranz, Maria Jesús, Banaschewski, Tobias, Bau, Claiton, Bellgrove, Mark, Biederman, Joseph, Brikell, Isabell, Buitelaar, Jan K., Burton, Christie L., Casas, Miguel, Crosbie, Jennifer, Doyle, Alysa E., Ebstein, Richard P., Elia, Josephine, Elizabeth, Corfield C., Grevet, Eugenio, Grizenko, Natalie, Havdahl, Alexandra, Hawi, Ziarih, Hebebrand, Johannes, Hervas, Amaia, Hohmann, Sarah, Haavik, Jan, Joober, Ridha, Kent, Lindsey, Kuntsi, Jonna, Langley, Kate, Larsson, Henrik, Lesch, Klaus-Peter, Leung, Patrick W. L., Liao, Calwing, Loo, Sandra K., Martin, Joanna, Martin, Nicholas G., Medland, Sarah E., Miranda, Ana, Mota, Nina Roth, Oades, Robert D., Ramos-Quiroga, Josep Antoni, Reif, Andreas, Rietschel, Marcella, Roeyers, Herbert, Rohde, Luis Augusto, Rothenberger, Aribert, Rovira, Paula, Sánchez-Mora, Cristina, Schachar, Russell James, Sengupta, Sarojini, Artigas, Maria Soler, Steinhausen, Hans-Christoph, Thapar, Anita, Witt, Stephanie H., Yang, Li, Zayats, Tetyana, Zhang-James, Yanli, Cormand, Bru, Hougaard, David M., Neale, Benjamin M., Franke, Barbara, Faraone, Stephen V., and Børglum, Anders D.

Subjects
Medizin
Abstract

The original version of this Article contained an error in the spelling of the author Marta Ribasés, which was incorrectly given as Marta Ribasas. This has now been corrected in both the PDF and HTML versions of the Article. CA extern, Korrektur zu: 10.1038/s41467-020-20443-2

Published
2021

157. Risk variants and polygenic architecture of disruptive behavior disorders in the context of attention-deficit/hyperactivity disorder

Author

Demontis, Ditte, Walters, Raymond K., Rajagopal, Veera M., Waldman, Irwin D., Grove, Jakob, Als, Thomas D., Dalsgaard, Søren, Ribasas, Marta, Bybjerg-Grauholm, Jonas, Bækvad-Hansen, Maria, Werge, Thomas, Nordentoft, Merete, Mors, Ole, Mortensen, Preben Bo, (PGC), ADHD Working Group of the Psychiatric Genomics Consortium, Andreassen, Ole A., Arranz, Maria Jesús, Banaschewski, Tobias, Bau, Claiton, Bellgrove, Mark, Biederman, Joseph, Brikell, Isabell, Buitelaar, Jan K., Burton, Christie L., Casas, Miguel, Crosbie, Jennifer, Doyle, Alysa E., Ebstein, Richard P., Elia, Josephine, Elizabeth, Corfield C., Grevet, Eugenio, Grizenko, Natalie, Havdahl, Alexandra, Hawi, Ziarih, Hebebrand, Johannes, Hervas, Amaia, Hohmann, Sarah, Haavik, Jan, Joober, Ridha, Kent, Lindsey, Kuntsi, Jonna, Langley, Kate, Larsson, Henrik, Lesch, Klaus-Peter, Leung, Patrick W. L., Liao, Calwing, Loo, Sandra K., Martin, Joanna, Martin, Nicholas G., Medland, Sarah E., Miranda, Ana, Mota, Nina Roth, Oades, Robert D., Ramos-Quiroga, Josep Antoni, Reif, Andreas, Rietschel, Marcella, Roeyers, Herbert, Rohde, Luis Augusto, Rothenberger, Aribert, Rovira, Paula, Sánchez-Mora, Cristina, Schachar, Russell James, Sengupta, Sarojini, Artigas, Maria Soler, Steinhausen, Hans-Christoph, Thapar, Anita, Witt, Stephanie H., Yang, Li, Zayats, Tetyana, Zhang-James, Yanli, Cormand, Bru, Hougaard, David M., Neale, Benjamin M., Franke, Barbara, Faraone, Stephen V., Børglum, Anders D., University of St Andrews. School of Medicine, University of St Andrews. Institute of Behavioural and Neural Sciences, University of St Andrews. Cellular Medicine Division, Institut Català de la Salut, [Demontis D, Rajagopal VM, Als TD] The Lundbeck Foundation Initiative for Integrative Psychiatric Research, iPSYCH, Aarhus, Denmark. Center for Genomics and Personalized Medicine, Aarhus, Denmark. Department of Biomedicine - Human Genetics, Aarhus University, Aarhus, Denmark. [Walters RK] Analytic and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA. Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA. [Waldman ID] Department of Psychology, Emory University, Atlanta, GA, USA. [Grove J] The Lundbeck Foundation Initiative for Integrative Psychiatric Research, iPSYCH, Aarhus, Denmark. Center for Genomics and Personalized Medicine, Aarhus, Denmark. Department of Biomedicine - Human Genetics, Aarhus University, Aarhus, Denmark. [Ribasés M] Unitat de Psiquiatria Genètica, Grup de recerca en Psiquiatria, salut mental i addiccions, Vall d’Hebron Institut de Recerca (VHIR), Barcelona, Spain. Universitat Autònoma de Barcelona, Bellaterra, Spain. Servei de Psiquiatria, Vall d’Hebron Hospital Universitari, Barcelona, Spain. Biomedical Network Research Center on Mental Health (CIBERSAM), Instituto de Salud Carlos III, Madrid, Spain. Departament de Genètica, Microbiologia i Estadística, Facultat de Biologia, Universitat de Barcelona, Barcelona, Catalonia, Spain, and Vall d'Hebron Barcelona Hospital Campus

Subjects
Male, 0301 basic medicine, Multifactorial Inheritance, Trastorns per dèficit d'atenció amb hiperactivitat en els infants, Medizin, General Physics and Astronomy, Genome-wide association study, Comorbidity, Genome-wide association studies, Attention deficit disorder with hyperactivity in children, conducta y mecanismos de la conducta::conducta::conducta y mecanismos de la conducta::conducta::conducta infantil::conducta problemática [PSIQUIATRÍA Y PSICOLOGÍA], Cohort Studies, 0302 clinical medicine, Mental Disorders::Neurodevelopmental Disorders::Attention Deficit and Disruptive Behavior Disorders::Attention Deficit Disorder with Hyperactivity [PSYCHIATRY AND PSYCHOLOGY], Risk Factors, 2.1 Biological and endogenous factors, Medicine, Attention Deficit Disorder with Hyperactivity/epidemiology, Aetiology, Child, China/epidemiology, Violence Research, Pediatric, Multidisciplinary, Genetic Predisposition to Disease/genetics, Attention Deficit and Disruptive Behavior Disorders/epidemiology, Single Nucleotide, 3. Good health, Europe, Mental Health, Attention Deficit and Disruptive Behavior Disorders, Cohort, Genome-Wide Association Study/methods, Attention Deficit Disorder (ADD), Female, medicine.symptom, RC0321 Neuroscience. Biological psychiatry. Neuropsychiatry, Clinical psychology, China, Investigative Techniques::Epidemiologic Methods::Epidemiologic Research Design::Genome-Wide Association Study [ANALYTICAL, DIAGNOSTIC AND THERAPEUTIC TECHNIQUES, AND EQUIPMENT], Science, Context (language use), Locus (genetics), QH426 Genetics, Polymorphism, Single Nucleotide, behavioral disciplines and activities, Article, General Biochemistry, Genetics and Molecular Biology, Europe/epidemiology, 03 medical and health sciences, Aggressiveness in children, Behavioral and Social Science, mental disorders, Genetics, ADHD, Humans, SNP, Attention deficit hyperactivity disorder, Genetic Predisposition to Disease, Polymorphism, Author Correction, QH426, Multifactorial Inheritance/genetics, Neurodevelopmental disorders Donders Center for Medical Neuroscience [Radboudumc 7], business.industry, Aggression, Prevention, Human Genome, DAS, General Chemistry, Agressivitat en els infants, Heritability, medicine.disease, Attention Deficit Hyperactivity Disorder (ADHD), Behavior and Behavior Mechanisms::Behavior::Behavior and Behavior Mechanisms::Behavior::Child Behavior::Problem Behavior [PSYCHIATRY AND PSYCHOLOGY], Brain Disorders, Genòmica, ADHD Working Group of the Psychiatric Genomics Consortium, Trastorn per dèficit d'atenció amb hiperactivitat, 030104 developmental biology, Attention Deficit Disorder with Hyperactivity, técnicas de investigación::métodos epidemiológicos::diseño de la investigación epidemiológica::estudio de asociación genómica completa [TÉCNICAS Y EQUIPOS ANALÍTICOS, DIAGNÓSTICOS Y TERAPÉUTICOS], RC0321, trastornos mentales::trastornos del desarrollo neurológico::trastornos conductuales disruptivos y déficit de atención::trastornos de déficit de atención con hiperactividad [PSIQUIATRÍA Y PSICOLOGÍA], business, 030217 neurology & neurosurgery, Genome-Wide Association Study
Abstract

Attention-Deficit/Hyperactivity Disorder (ADHD) is a childhood psychiatric disorder often comorbid with disruptive behavior disorders (DBDs). Here, we report a GWAS meta-analysis of ADHD comorbid with DBDs (ADHD + DBDs) including 3802 cases and 31,305 controls. We identify three genome-wide significant loci on chromosomes 1, 7, and 11. A meta-analysis including a Chinese cohort supports that the locus on chromosome 11 is a strong risk locus for ADHD + DBDs across European and Chinese ancestries (rs7118422, P = 3.15×10−10, OR = 1.17). We find a higher SNP heritability for ADHD + DBDs (h2SNP = 0.34) when compared to ADHD without DBDs (h2SNP = 0.20), high genetic correlations between ADHD + DBDs and aggressive (rg = 0.81) and anti-social behaviors (rg = 0.82), and an increased burden (polygenic score) of variants associated with ADHD and aggression in ADHD + DBDs compared to ADHD without DBDs. Our results suggest an increased load of common risk variants in ADHD + DBDs compared to ADHD without DBDs, which in part can be explained by variants associated with aggressive behavior., ADHD is often found to be comorbid with disruptive behavior disorders, but the genetic loci underlying this comorbidity are unknown. Here, the authors have performed a GWAS meta-analysis of ADHD with disruptive behavior disorders, finding three genome-wide significant loci in Europeans, and replicating one in a Chinese cohort.

Published
2021

158. Studies of perception, attention and motor function in schizophrenia

Author

Bellgrove, Mark A.

Subjects
ComputingMilieux_COMPUTERSANDEDUCATION, ComputerApplications_COMPUTERSINOTHERSYSTEMS, Uncategorized
Abstract

This thesis was scanned from the print manuscript for digital preservation and is copyright the author. Researchers can access this thesis by asking their local university, institution or public library to make a request on their behalf. Monash staff and postgraduate students can use the link in the References field.

Published
2021
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159. Virtual Histology of Cortical Thickness and Shared Neurobiology in 6 Psychiatric Disorders

Author

Committee, Writing, Disorder, Autism Spectrum, French, Leon, Grevet, Eugenio H, Groenewold, Nynke A, Grotegerd, Dominik, Gruber, Oliver, Gruner, Patricia, Guerrero-Pedraza, Amalia, Gur, Raquel E, Gur, Ruben C, Haar, Shlomi, Haarman, Bartholomeus C M, Thomopoulos, Sophia I, Haavik, Jan, Hahn, Tim, Hajek, Tomas, Harrison, Benjamin J, Harrison, Neil A, Hartman, Catharina A, Whalley, Heather C, Heslenfeld, Dirk J, Hibar, Derrek P, Hilland, Eva, Pozzi, Elena, Hirano, Yoshiyuki, Ho, Tiffany C, Hoekstra, Pieter J, Hoekstra, Liesbeth, Hohmann, Sarah, Hong, L. E., Höschl, Cyril, Høvik, Marie F, Howells, Fleur M, Nenadic, Igor, Abe, Yoshinari, Jalbrzikowski, Maria, James, Anthony C, Janssen, Joost, Jaspers-Fayer, Fern, Xu, Jian, Jonassen, Rune, Karkashadze, Georgii, King, Joseph A, Kircher, Tilo, Kirschner, Matthias, Abé, Christoph, Koch, Kathrin, Kochunov, Peter, Kohls, Gregor, Konrad, Kerstin, Krämer, Bernd, Krug, Axel, Kuntsi, Jonna, Kwon, Jun Soo, Landén, Mikael, Landrø, Nils I, Anticevic, Alan, Lazaro, Luisa, Lebedeva, Irina S, Leehr, Elisabeth J, Lera-Miguel, Sara, Lesch, Klaus-Peter, Lochner, Christine, Louza, Mario R, Luna, Beatriz, Lundervold, Astri J, MacMaster, Frank P, Alda, Martin, Maglanoc, Luigi A, Malpas, Charles B, Portella, Maria J, Marsh, Rachel, Martyn, Fiona M, Mataix-Cols, David, Mathalon, Daniel H, McCarthy, Hazel, McDonald, Colm, McPhilemy, Genevieve, Aleman, Andre, Meinert, Susanne, Menchón, José M, Minuzzi, Luciano, Mitchell, Philip B, Moreno, Carmen, Morgado, Pedro, Muratori, Filippo, Murphy, Clodagh M, Murphy, Declan, Mwangi, Benson, Alloza, Clara, Nabulsi, Leila, Nakagawa, Akiko, Nakamae, Takashi, Namazova, Leyla, Narayanaswamy, Janardhanan, Jahanshad, Neda, Nguyen, Danai D, Nicolau, Rosa, O'Gorman Tuura, Ruth L, O'Hearn, Kirsten, Alonso-Lana, Silvia, Oosterlaan, Jaap, Opel, Nils, Ophoff, Roel A, Oranje, Bob, García de la Foz, Victor Ortiz, Overs, Bronwyn J, Paloyelis, Yannis, Pantelis, Christos, Parellada, Mara, Pauli, Paul, Disorder, Bipolar, Ameis, Stephanie H, Picó-Pérez, Maria, Picon, Felipe A, Piras, Fabrizio, Piras, Federica, Plessen, Kerstin J, Pomarol-Clotet, Edith, Preda, Adrian, Puig, Olga, Quidé, Yann, Radua, Joaquim, Anagnostou, Evdokia, Ramos-Quiroga, J Antoni, Rasser, Paul E, Rauer, Lisa, Reddy, Janardhan, Redlich, Ronny, Reif, Andreas, Reneman, Liesbeth, Repple, Jonathan, Retico, Alessandra, Richarte, Vanesa, McIntosh, Andrew A, Richter, Anja, Rosa, Pedro G P, Rubia, Katya K, Hashimoto, Ryota, Sacchet, Matthew D, Salvador, Raymond, Santonja, Javier, Sarink, Kelvin, Sarró, Salvador, Satterthwaite, Theodore D, Arango, Celso, Sawa, Akira, Schall, Ulrich, Schofield, Peter R, Schrantee, Anouk, Seitz, Jochen, Serpa, Mauricio H, Setién-Suero, Esther, Shaw, Philip, Shook, Devon, Silk, Tim J, Arnold, Paul D, Sim, Kang, Simon, Schmitt, Simpson, Helen Blair, Singh, Aditya, Skoch, Antonin, Skokauskas, Norbert, Soares, Jair C, Soreni, Noam, Soriano-Mas, Carles, Spalletta, Gianfranco, Asherson, Philip, Spaniel, Filip, Lawrie, Stephen M, Stern, Emily R, Stewart, S Evelyn, Takayanagi, Yoichiro, Temmingh, Henk S, Tolin, David F, Tomecek, David, Tordesillas-Gutiérrez, Diana, Tosetti, Michela, Assogna, Francesca, Uhlmann, Anne, van Amelsvoort, Therese, van der Wee, Nic J A, van der Werff, Steven J A, van Haren, Neeltje E M, van Wingen, Guido A, Vance, Alasdair, Vázquez-Bourgon, Javier, Vecchio, Daniela, Venkatasubramanian, Ganesan, Auzias, Guillaume, Vieta, Eduard, Vilarroya, Oscar, Vives-Gilabert, Yolanda, Voineskos, Aristotle N, Völzke, Henry, von Polier, Georg G, Walton, Esther, Weickert, Thomas W, Weickert, Cynthia Shannon, Weideman, Andrea S, Ayesa-Arriola, Rosa, Wittfeld, Katharina, Wolf, Daniel H, Wu, Mon-Ju, Yang, T. T., Yang, Sikun, Yoncheva, Yuliya, Yun, Je-Yeon, Cheng, Yuqi, Zanetti, Marcus V, Ziegler, Georg C, Bakker, Geor, Franke, Barbara, Hoogman, Martine, Buitelaar, Jan K, van Rooij, Daan, Andreassen, Ole A, Ching, Christopher R K, Veltman, Dick J, Schmaal, Lianne, Stein, Dan J, van den Heuvel, Odile A, Disorder, Major Depressive, Banaj, Nerisa, Turner, Jessica A, van Erp, Theo G M, Pausova, Zdenka, Thompson, Paul M, Paus, Tomáš, Attention-Deficit/Hyperactivity Disorder, Banaschewski, Tobias, Bandeira, Cibele E, Baranov, Alexandr, Bargalló, Núria, Bau, Claiton H D, Baumeister, Sarah, Baune, Bernhard T, Bellgrove, Mark A, Benedetti, Francesco, Disorder, Obsessive-Compulsive, Bertolino, Alessandro, Boedhoe, Premika S W, Boks, Marco, Bollettini, Irene, Del Mar Bonnin, Caterina, Borgers, Tiana, Borgwardt, Stefan, Brandeis, Daniel, Brennan, Brian P, Bruggemann, Jason M, Groups, Schizophrenia ENIGMA Working, Bülow, Robin, Busatto, Geraldo F, Calderoni, Sara, Calhoun, Vince D, Calvo, Rosa, Canales-Rodríguez, Erick J, Cannon, Dara M, Carr, Vaughan J, Cascella, Nicola, Cercignani, Mara, Patel, Yash, Chaim-Avancini, Tiffany M, Christakou, Anastasia, Coghill, David, Conzelmann, Annette, Crespo-Facorro, Benedicto, Cubillo, Ana I, Cullen, Kathryn R, Cupertino, Renata B, Daly, Eileen, Dannlowski, Udo, Parker, Nadine, Davey, Christopher G, Denys, Damiaan, Deruelle, Christine, Di Giorgio, Annabella, Dickie, Erin W, Dima, Danai, Dohm, Katharina, Ehrlich, Stefan, Ely, Benjamin A, Erwin-Grabner, Tracy, Shin, Jean, Ethofer, Thomas, Fair, Damien A, Fallgatter, Andreas, Faraone, Stephen V, Fatjó-Vilas, Mar, Fedor, Jennifer M, Fitzgerald, Kate D, Ford, Judith M, Frodl, Thomas, Fu, Cynthia H Y, Howard, Derek, Fullerton, Janice M, Gabel, Matt C, Glahn, David C, Roberts, Gloria, Gogberashvili, Tinatin, Goikolea, Jose M, Gotlib, Ian H, Goya-Maldonado, Roberto, Grabe, Hans, Green, Melissa J, Patel, Y., Parker, N., Shin, J., Howard, D., French, L., Thomopoulos, S. I., Pozzi, E., Abe, Y., Abe, C., Anticevic, A., Alda, M., Aleman, A., Alloza, C., Alonso-Lana, S., Ameis, S. H., Anagnostou, E., Mcintosh, A. A., Arango, C., Arnold, P. D., Asherson, P., Assogna, F., Auzias, G., Ayesa-Arriola, R., Bakker, G., Banaj, N., Banaschewski, T., Bandeira, C. E., Baranov, A., Bargallo, N., Bau, C. H. D., Baumeister, S., Baune, B. T., Bellgrove, M. A., Benedetti, F., Bertolino, A., Boedhoe, P. S. W., Boks, M., Bollettini, I., Del Mar Bonnin, C., Borgers, T., Borgwardt, S., Brandeis, D., Brennan, B. P., Bruggemann, J. M., Bulow, R., Busatto, G. F., Calderoni, S., Calhoun, V. D., Calvo, R., Canales-Rodriguez, E. J., Cannon, D. M., Carr, V. J., Cascella, N., Cercignani, M., Chaim-Avancini, T. M., Christakou, A., Coghill, D., Conzelmann, A., Crespo-Facorro, B., Cubillo, A. I., Cullen, K. R., Cupertino, R. B., Daly, E., Dannlowski, U., Davey, C. G., Denys, D., Deruelle, C., Di Giorgio, A., Dickie, E. W., Dima, D., Dohm, K., Ehrlich, S., Ely, B. A., Erwin-Grabner, T., Ethofer, T., Fair, D. A., Fallgatter, A. J., Faraone, S. V., Fatjo-Vilas, M., Fedor, J. M., Fitzgerald, K. D., Ford, J. M., Frodl, T., Fu, C. H. Y., Fullerton, J. M., Gabel, M. C., Glahn, D. C., Roberts, G., Gogberashvili, T., Goikolea, J. M., Gotlib, I. H., Goya-Maldonado, R., Grabe, H. J., Green, M. J., Grevet, E. H., Groenewold, N. A., Grotegerd, D., Gruber, O., Gruner, P., Guerrero-Pedraza, A., Gur, R. E., Gur, R. C., Haar, S., Haarman, B. C. M., Haavik, J., Hahn, T., Hajek, T., Harrison, B. J., Harrison, N. A., Hartman, C. A., Whalley, H. C., Heslenfeld, D. J., Hibar, D. P., Hilland, E., Hirano, Y., Ho, T. C., Hoekstra, P. J., Hoekstra, L., Hohmann, S., Hong, L. E., Hoschl, C., Hovik, M. F., Howells, F. M., Nenadic, I., Jalbrzikowski, M., James, A. C., Janssen, J., Jaspers-Fayer, F., Xu, J., Jonassen, R., Karkashadze, G., King, J. A., Kircher, T., Kirschner, M., Koch, K., Kochunov, P., Kohls, G., Konrad, K., Kramer, B., Krug, A., Kuntsi, J., Kwon, J. S., Landen, M., Landro, N. I., Lazaro, L., Lebedeva, I. S., Leehr, E. J., Lera-Miguel, S., Lesch, K. -P., Lochner, C., Louza, M. R., Luna, B., Lundervold, A. J., Macmaster, F. P., Maglanoc, L. A., Malpas, C. B., Portella, M. J., Marsh, R., Martyn, F. M., Mataix-Cols, D., Mathalon, D. H., Mccarthy, H., Mcdonald, C., Mcphilemy, G., Meinert, S., Menchon, J. M., Minuzzi, L., Mitchell, P. B., Moreno, C., Morgado, P., Muratori, F., Murphy, C. M., Murphy, D., Mwangi, B., Nabulsi, L., Nakagawa, A., Nakamae, T., Namazova, L., Narayanaswamy, J., Jahanshad, N., Nguyen, D. D., Nicolau, R., O'Gorman Tuura, R. L., O'Hearn, K., Oosterlaan, J., Opel, N., Ophoff, R. A., Oranje, B., Garcia De La Foz, V. O., Overs, B. J., Paloyelis, Y., Pantelis, C., Parellada, M., Pauli, P., Pico-Perez, M., Picon, F. A., Piras, F., Plessen, K. J., Pomarol-Clotet, E., Preda, A., Puig, O., Quide, Y., Radua, J., Ramos-Quiroga, J. A., Rasser, P. E., Rauer, L., Reddy, J., Redlich, R., Reif, A., Reneman, L., Repple, J., Retico, A., Richarte, V., Richter, A., Rosa, P. G. P., Rubia, K. K., Hashimoto, R., Sacchet, M. D., Salvador, R., Santonja, J., Sarink, K., Sarro, S., Satterthwaite, T. D., Sawa, A., Schall, U., Schofield, P. R., Schrantee, A., Seitz, J., Serpa, M. H., Setien-Suero, E., Shaw, P., Shook, D., Silk, T. J., Sim, K., Simon, S., Simpson, H. B., Singh, A., Skoch, A., Skokauskas, N., Soares, J. C., Soreni, N., Soriano-Mas, C., Spalletta, G., Spaniel, F., Lawrie, S. M., Stern, E. R., Stewart, S. E., Takayanagi, Y., Temmingh, H. S., Tolin, D. F., Tomecek, D., Tordesillas-Gutierrez, D., Tosetti, M., Uhlmann, A., Van Amelsvoort, T., Van Der Wee, N. J. A., Van Der Werff, S. J. A., Van Haren, N. E. M., Van Wingen, G. A., Vance, A., Vazquez-Bourgon, J., Vecchio, D., Venkatasubramanian, G., Vieta, E., Vilarroya, O., Vives-Gilabert, Y., Voineskos, A. N., Volzke, H., Von Polier, G. G., Walton, E., Weickert, T. W., Weickert, C. S., Weideman, A. S., Wittfeld, K., Wolf, D. H., Wu, M. -J., Yang, T. T., Yang, K., Yoncheva, Y., Yun, J. -Y., Cheng, Y., Zanetti, M. V., Ziegler, G. C., Franke, B., Hoogman, M., Buitelaar, J. K., Van Rooij, D., Andreassen, O. A., Ching, C. R. K., Veltman, D. J., Schmaal, L., Stein, D. J., Van Den Heuvel, O. A., Turner, J. A., Van Erp, T. G. M., Pausova, Z., Thompson, P. M., Paus, T., Institut de Neurosciences de la Timone (INT), Aix Marseille Université (AMU)-Centre National de la Recherche Scientifique (CNRS), Pediatric surgery, Radiology and nuclear medicine, Anatomy and neurosciences, Psychiatry, Amsterdam Neuroscience - Brain Imaging, Amsterdam Neuroscience - Compulsivity, Impulsivity & Attention, Amsterdam Neuroscience - Mood, Anxiety, Psychosis, Stress & Sleep, Amsterdam Neuroscience - Neurodegeneration, Psychiatrie & Neuropsychologie, RS: MHeNs - R2 - Mental Health, MUMC+: MA Med Staf Spec Psychiatrie (9), Adult Psychiatry, ANS - Compulsivity, Impulsivity & Attention, General Paediatrics, ARD - Amsterdam Reproduction and Development, Radiology and Nuclear Medicine, APH - Personalized Medicine, ANS - Brain Imaging, ANS - Mood, Anxiety, Psychosis, Stress & Sleep, APH - Mental Health, University of Zurich, Clinical Cognitive Neuropsychiatry Research Program (CCNP), Clinical Neuropsychology, Interdisciplinary Centre Psychopathology and Emotion regulation (ICPE), Child and Adolescent Psychiatry / Psychology, IBBA, and Cognitive Psychology

Subjects
Male, Obsessive-Compulsive Disorder, Bipolar Disorder, Autism Spectrum Disorder, Autism, [SDV]Life Sciences [q-bio], Gene Expression, cytology [Cerebral Cortex], Cohort Studies, Fetal Development, physiology [Gene Expression], 2738 Psychiatry and Mental Health, 0302 clinical medicine, diagnostic imaging [Cerebral Cortex], SCHIZOPHRENIA, BRAIN, Child, Obsessive-compulsive disorder (OCD), Original Investigation, Aged, 80 and over, Cerebral Cortex, 0303 health sciences, pathology [Depressive Disorder, Major], Principal Component Analysis, Adolescent psychiatry, 10058 Department of Child and Adolescent Psychiatry, Middle Aged, diagnostic imaging [Obsessive-Compulsive Disorder], REGIONS, Magnetic Resonance Imaging, 3. Good health, FALSE DISCOVERY RATE, Psychiatry and Mental health, Autism spectrum disorder, Schizophrenia, growth & development [Cerebral Cortex], Child, Preschool, Major depressive disorder, diagnostic imaging [Schizophrenia], Esquizofrènia, Female, Psiquiatria infantil, Psiquiatria de l'adolescència, diagnostic imaging [Autism Spectrum Disorder], Adult, medicine.medical_specialty, Adolescent, Human Development, 610 Medicine & health, diagnostic imaging [Bipolar Disorder], pathology [Autism Spectrum Disorder], diagnostic imaging [Depressive Disorder, Major], 03 medical and health sciences, Young Adult, All institutes and research themes of the Radboud University Medical Center, Neuroimaging, SDG 3 - Good Health and Well-being, CEREBRAL-CORTEX, Child psychiatry, medicine, Attention deficit hyperactivity disorder, Humans, Bipolar disorder, ddc:610, Psychiatry, pathology [Schizophrenia], 030304 developmental biology, Aged, Depressive Disorder, Major, Neurodevelopmental disorders Donders Center for Medical Neuroscience [Radboudumc 7], business.industry, DENDRITE, Computational Biology, Correction, pathology [Attention Deficit Disorder with Hyperactivity], physiology [Fetal Development], medicine.disease, PATHOLOGY, pathology [Bipolar Disorder], pathology [Obsessive-Compulsive Disorder], 10036 Medical Clinic, Attention Deficit Disorder with Hyperactivity, 10054 Clinic for Psychiatry, Psychotherapy, and Psychosomatics, Case-Control Studies, DENSITY, ORIGINS, HIPPOCAMPUS, diagnostic imaging [Attention Deficit Disorder with Hyperactivity], pathology [Cerebral Cortex], Autisme, business, Neuroscience, 030217 neurology & neurosurgery, physiology [Human Development]
Abstract

[Importance] Large-scale neuroimaging studies have revealed group differences in cortical thickness across many psychiatric disorders. The underlying neurobiology behind these differences is not well understood., [Objective] To determine neurobiologic correlates of group differences in cortical thickness between cases and controls in 6 disorders: attention-deficit/hyperactivity disorder (ADHD), autism spectrum disorder (ASD), bipolar disorder (BD), major depressive disorder (MDD), obsessive-compulsive disorder (OCD), and schizophrenia., [Design, Setting, and Participants] Profiles of group differences in cortical thickness between cases and controls were generated using T1-weighted magnetic resonance images. Similarity between interregional profiles of cell-specific gene expression and those in the group differences in cortical thickness were investigated in each disorder. Next, principal component analysis was used to reveal a shared profile of group difference in thickness across the disorders. Analysis for gene coexpression, clustering, and enrichment for genes associated with these disorders were conducted. Data analysis was conducted between June and December 2019. The analysis included 145 cohorts across 6 psychiatric disorders drawn from the ENIGMA consortium. The numbers of cases and controls in each of the 6 disorders were as follows: ADHD: 1814 and 1602; ASD: 1748 and 1770; BD: 1547 and 3405; MDD: 2658 and 3572; OCD: 2266 and 2007; and schizophrenia: 2688 and 3244., [Main Outcomes and Measures] Interregional profiles of group difference in cortical thickness between cases and controls., [Results] A total of 12 721 cases and 15 600 controls, ranging from ages 2 to 89 years, were included in this study. Interregional profiles of group differences in cortical thickness for each of the 6 psychiatric disorders were associated with profiles of gene expression specific to pyramidal (CA1) cells, astrocytes (except for BD), and microglia (except for OCD); collectively, gene-expression profiles of the 3 cell types explain between 25% and 54% of variance in interregional profiles of group differences in cortical thickness. Principal component analysis revealed a shared profile of difference in cortical thickness across the 6 disorders (48% variance explained); interregional profile of this principal component 1 was associated with that of the pyramidal-cell gene expression (explaining 56% of interregional variation). Coexpression analyses of these genes revealed 2 clusters: (1) a prenatal cluster enriched with genes involved in neurodevelopmental (axon guidance) processes and (2) a postnatal cluster enriched with genes involved in synaptic activity and plasticity-related processes. These clusters were enriched with genes associated with all 6 psychiatric disorders., [Conclusions and Relevance] In this study, shared neurobiologic processes were associated with differences in cortical thickness across multiple psychiatric disorders. These processes implicate a common role of prenatal development and postnatal functioning of the cerebral cortex in these disorders.

Published
2021

160. Analysis of structural brain asymmetries in attention-deficit/hyperactivity disorder in 39 datasets

Author

Postema, M.C., Hoogman, M., Ambrosino, S., Asherson, P., Banaschewski, T., Bandeira, C.E., Baranov, A., Bau, C.H.D., Baumeister, S., Baur-Streubel, R., Bellgrove, Mark A., Biederman, J., Bralten, J.B., Brandeis, D., Brem, S., Buitelaar, J.K., Busatto, G.F., Castellanos, F.X., Cercignani, M., Chaim-Avancini, T.M., Chantiluke, K.C., Christakou, A., Coghill, D., Conzelmann, A., Cubillo, A.I., Cupertino, R.B., Zeeuw, P. de, Doyle, A.E., Durston, S., Earl, E.A., Epstein, J.N., Ethofer, T., Fair, D.A., Fallgatter, A.J., Faraone, S.V, Frodl, T., Gabel, M.C., Gogberashvili, T., Grevet, E.H., Haavik, J., Harrison, N.A., Hartman, Catharina A., Heslenfeld, D.J., Hoekstra, P.J., Hohmann, S., Høvik, M.F., Jernigan, T.L., Kardatzki, B., Karkashadze, G., Kelly, C., Kohls, G., Konrad, K., Kuntsi, J., Lazaro, L., Lera-Miguel, S., Lesch, K.P., Louza, M.R., Lundervold, A.J., Malpas, C.B., Mattos, P., McCarthy, H., Namazova-Baranova, L., Nicolau, R., Nigg, J.T., Novotny, S.E., Weiss, E. Oberwelland, Tuura, R.L. O'Gorman, Oosterlaan, J., Oranje, B., Paloyelis, Y., Pauli, P., Picon, F.A., Plessen, K.J., Ramos-Quiroga, J.A., Reif, A., Reneman, L., Rosa, P.G., Rubia, K., Schrantee, A., Schweren, L.J., Seitz, J., Shaw, P., Silk, T.J., Skokauskas, N., Vila, J.C. Soliva, Stevens, M.C., Sudre, G., Tamm, L., Tovar-Moll, F., Erp, T.G. van, Vance, A., Vilarroya, O., Vives-Gilabert, Y., Polier, G.G. von, Walitza, S., Yoncheva, Y.N., Zanetti, M.V., Ziegler, G.C., Glahn, D.C., Fisher, S.E., Franke, B., Francks, C., Postema, M.C., Hoogman, M., Ambrosino, S., Asherson, P., Banaschewski, T., Bandeira, C.E., Baranov, A., Bau, C.H.D., Baumeister, S., Baur-Streubel, R., Bellgrove, Mark A., Biederman, J., Bralten, J.B., Brandeis, D., Brem, S., Buitelaar, J.K., Busatto, G.F., Castellanos, F.X., Cercignani, M., Chaim-Avancini, T.M., Chantiluke, K.C., Christakou, A., Coghill, D., Conzelmann, A., Cubillo, A.I., Cupertino, R.B., Zeeuw, P. de, Doyle, A.E., Durston, S., Earl, E.A., Epstein, J.N., Ethofer, T., Fair, D.A., Fallgatter, A.J., Faraone, S.V, Frodl, T., Gabel, M.C., Gogberashvili, T., Grevet, E.H., Haavik, J., Harrison, N.A., Hartman, Catharina A., Heslenfeld, D.J., Hoekstra, P.J., Hohmann, S., Høvik, M.F., Jernigan, T.L., Kardatzki, B., Karkashadze, G., Kelly, C., Kohls, G., Konrad, K., Kuntsi, J., Lazaro, L., Lera-Miguel, S., Lesch, K.P., Louza, M.R., Lundervold, A.J., Malpas, C.B., Mattos, P., McCarthy, H., Namazova-Baranova, L., Nicolau, R., Nigg, J.T., Novotny, S.E., Weiss, E. Oberwelland, Tuura, R.L. O'Gorman, Oosterlaan, J., Oranje, B., Paloyelis, Y., Pauli, P., Picon, F.A., Plessen, K.J., Ramos-Quiroga, J.A., Reif, A., Reneman, L., Rosa, P.G., Rubia, K., Schrantee, A., Schweren, L.J., Seitz, J., Shaw, P., Silk, T.J., Skokauskas, N., Vila, J.C. Soliva, Stevens, M.C., Sudre, G., Tamm, L., Tovar-Moll, F., Erp, T.G. van, Vance, A., Vilarroya, O., Vives-Gilabert, Y., Polier, G.G. von, Walitza, S., Yoncheva, Y.N., Zanetti, M.V., Ziegler, G.C., Glahn, D.C., Fisher, S.E., Franke, B., and Francks, C.

Abstract

Item does not contain fulltext, OBJECTIVE: Some studies have suggested alterations of structural brain asymmetry in attention-deficit/hyperactivity disorder (ADHD), but findings have been contradictory and based on small samples. Here, we performed the largest ever analysis of brain left-right asymmetry in ADHD, using 39 datasets of the ENIGMA consortium. METHODS: We analyzed asymmetry of subcortical and cerebral cortical structures in up to 1,933 people with ADHD and 1,829 unaffected controls. Asymmetry Indexes (AIs) were calculated per participant for each bilaterally paired measure, and linear mixed effects modeling was applied separately in children, adolescents, adults, and the total sample, to test exhaustively for potential associations of ADHD with structural brain asymmetries. RESULTS: There was no evidence for altered caudate nucleus asymmetry in ADHD, in contrast to prior literature. In children, there was less rightward asymmetry of the total hemispheric surface area compared to controls (t = 2.1, p = .04). Lower rightward asymmetry of medial orbitofrontal cortex surface area in ADHD (t = 2.7, p = .01) was similar to a recent finding for autism spectrum disorder. There were also some differences in cortical thickness asymmetry across age groups. In adults with ADHD, globus pallidus asymmetry was altered compared to those without ADHD. However, all effects were small (Cohen's d from -0.18 to 0.18) and would not survive study-wide correction for multiple testing. CONCLUSION: Prior studies of altered structural brain asymmetry in ADHD were likely underpowered to detect the small effects reported here. Altered structural asymmetry is unlikely to provide a useful biomarker for ADHD, but may provide neurobiological insights into the trait.

Published
2021

161. The World Federation of ADHD International Consensus Statement: 208 Evidence-based conclusions about the disorder

Author

Faraone, Stephen, V, Banaschewski, Tobias, Coghill, David, Zheng, Yi, Biederman, Joseph, Bellgrove, Mark A., Newcorn, Jeffrey H., Gignac, Martin, Al Saud, Nouf M., Manor, Iris, Rohde, Luis Augusto, Yang, Li, Cortese, Samuele, Almagor, Doron, Stein, Mark A., Albatti, Turki H., Aljoudi, Haya F., Alqahtani, Mohammed M. J., Asherson, Philip, Atwoli, Lukoye, Bolte, Sven, Buitelaar, Jan K., Crunelle, Cleo L., Daley, David, Dalsgaard, Soren, Doepfner, Manfred, Espinet, Stacey, Fitzgerald, Michael, Franke, Barbara, Gerlach, Manfred, Haavik, Jan, Hartman, Catharina A., Hartung, Cynthia M., Hinshaw, Stephen P., Hoekstra, Pieter J., Hollis, Chris, Kollins, Scott H., Kooij, J. J. Sandra, Kuntsi, Jonna, Larsson, Henrik, Li, Tingyu, Liu, Jing, Merzon, Eugene, Mattingly, Gregory, Mattos, Paulo, McCarthy, Suzanne, Mikami, Amori Yee, Molina, Brooke S. G., Nigg, Joel T., Purper-Ouakil, Diane, Omigbodun, Olayinka O., Polanczyk, Guilherme, V, Pollak, Yehuda, Poulton, Alison S., Rajkumar, Ravi Philip, Reding, Andrew, Reif, Andreas, Rubia, Katya, Rucklidge, Julia, Romanos, Marcel, Ramos-Quiroga, J. Antoni, Schellekens, Arnt, Scheres, Anouk, Schoeman, Renata, Schweitzer, Julie B., Shah, Henal, Solanto, Mary, V, Sonuga-Barke, Edmund, Soutullo, Cesar, Steinhausen, Hans-Christoph, Swanson, James M., Thapar, Anita, Tripp, Gail, van de Glind, Geurt, van den Brink, Wim, Van der Oord, Saskia, Venter, Andre, Vitiello, Benedetto, Walitza, Susanne, Wang, Yufeng, Faraone, Stephen, V, Banaschewski, Tobias, Coghill, David, Zheng, Yi, Biederman, Joseph, Bellgrove, Mark A., Newcorn, Jeffrey H., Gignac, Martin, Al Saud, Nouf M., Manor, Iris, Rohde, Luis Augusto, Yang, Li, Cortese, Samuele, Almagor, Doron, Stein, Mark A., Albatti, Turki H., Aljoudi, Haya F., Alqahtani, Mohammed M. J., Asherson, Philip, Atwoli, Lukoye, Bolte, Sven, Buitelaar, Jan K., Crunelle, Cleo L., Daley, David, Dalsgaard, Soren, Doepfner, Manfred, Espinet, Stacey, Fitzgerald, Michael, Franke, Barbara, Gerlach, Manfred, Haavik, Jan, Hartman, Catharina A., Hartung, Cynthia M., Hinshaw, Stephen P., Hoekstra, Pieter J., Hollis, Chris, Kollins, Scott H., Kooij, J. J. Sandra, Kuntsi, Jonna, Larsson, Henrik, Li, Tingyu, Liu, Jing, Merzon, Eugene, Mattingly, Gregory, Mattos, Paulo, McCarthy, Suzanne, Mikami, Amori Yee, Molina, Brooke S. G., Nigg, Joel T., Purper-Ouakil, Diane, Omigbodun, Olayinka O., Polanczyk, Guilherme, V, Pollak, Yehuda, Poulton, Alison S., Rajkumar, Ravi Philip, Reding, Andrew, Reif, Andreas, Rubia, Katya, Rucklidge, Julia, Romanos, Marcel, Ramos-Quiroga, J. Antoni, Schellekens, Arnt, Scheres, Anouk, Schoeman, Renata, Schweitzer, Julie B., Shah, Henal, Solanto, Mary, V, Sonuga-Barke, Edmund, Soutullo, Cesar, Steinhausen, Hans-Christoph, Swanson, James M., Thapar, Anita, Tripp, Gail, van de Glind, Geurt, van den Brink, Wim, Van der Oord, Saskia, Venter, Andre, Vitiello, Benedetto, Walitza, Susanne, and Wang, Yufeng

Abstract

Background: Misconceptions about ADHD stigmatize affected people, reduce credibility of providers, and pre-vent/delay treatment. To challenge misconceptions, we curated findings with strong evidence base. Methods: We reviewed studies with more than 2000 participants or meta-analyses from five or more studies or 2000 or more participants. We excluded meta-analyses that did not assess publication bias, except for meta-analyses of prevalence. For network meta-analyses we required comparison adjusted funnel plots. We excluded treatment studies with waiting-list or treatment as usual controls. From this literature, we extracted evidence-based assertions about the disorder. Results: We generated 208 empirically supported statements about ADHD. The status of the included statements as empirically supported is approved by 80 authors from 27 countries and 6 continents. The contents of the manuscript are endorsed by 366 people who have read this document and agree with its contents. Conclusions: Many findings in ADHD are supported by meta-analysis. These allow for firm statements about the nature, course, outcome causes, and treatments for disorders that are useful for reducing misconceptions and stigma.

Published
2021

162. The World Federation of ADHD International Consensus Statement: 208 evidence-based conclusions about the disorder

Author

CADDRA, Faraone, Stephen V., Banaschewski, Tobias, Coghill, David, Zheng, Yi, Biederman, Joseph, Bellgrove, Mark A., Newcorn, Jeffrey H., Gignac, Martin, Al Saud, Nouf M., Manor, Iris, Rohde, Luis Augusto, Yang, Li, Cortese, Samuele, Almagor, Doron, Stein, Mark A., Albatti, Turki H., Aljoudi, Haya F., Alqahtani, Mohammed M.J., Asherson, Philip, Atwoli, Lukoye, Bölte, Sven, Buitelaar, Jan K., Crunelle, Cleo L., Daley, David, Dalsgaard, Søren, Döpfner, Manfred, Espinet, Stacey, Fitzgerald, Michael, Franke, Barbara, Gerlach, Manfred, Haavik, Jan, Hartman, Catharina A., Hartung, Cynthia M., Hinshaw, Stephen P., Hoekstra, Pieter J., Hollis, Chris, Kollins, Scott H., Kooij, Johanna Jacoba Sandra, Kuntsi, Jonna, Larsson, Henrik, Li, Tingyu, Liu, Jing, Merzon, Eugene, Mattingly, Gregory, Mattos, Paulo, McCarthy, Suzanne, Mikami, Amori Yee, Molina, Brooke S.G., Nigg, Joel T., Purper-Ouakil, Diane, Omigbodun, Olayinka O., Polanczyk, Guilherme V., Pollak, Yehuda, Poulton, Alison S., Reif, Andreas, Rajkumar, Ravi Philip, Rubia, Katya, Reding, Andrew, Rucklidge, Julia, Romanos, Marcel, Ramos-Quiroga, J. Antoni, Schellekens, Arnt, Scheres, Anouk, Schoeman, Renata, Schweitzer, Julie B., Shah, Henal, Solanto, Mary V., Sonuga-Barke, Edmund, Soutullo, César, Steinhausen, Hans-Christoph, Swanson, James M., Thapar, Anita, Tripp, Gail, Glind, Geurt van de, Brink, Wim van den, Oord, Saskia van der, Venter, Andre, Vitiello, Benedetto, Walitza, Susanne, Wang, Yufeng, CADDRA, Faraone, Stephen V., Banaschewski, Tobias, Coghill, David, Zheng, Yi, Biederman, Joseph, Bellgrove, Mark A., Newcorn, Jeffrey H., Gignac, Martin, Al Saud, Nouf M., Manor, Iris, Rohde, Luis Augusto, Yang, Li, Cortese, Samuele, Almagor, Doron, Stein, Mark A., Albatti, Turki H., Aljoudi, Haya F., Alqahtani, Mohammed M.J., Asherson, Philip, Atwoli, Lukoye, Bölte, Sven, Buitelaar, Jan K., Crunelle, Cleo L., Daley, David, Dalsgaard, Søren, Döpfner, Manfred, Espinet, Stacey, Fitzgerald, Michael, Franke, Barbara, Gerlach, Manfred, Haavik, Jan, Hartman, Catharina A., Hartung, Cynthia M., Hinshaw, Stephen P., Hoekstra, Pieter J., Hollis, Chris, Kollins, Scott H., Kooij, Johanna Jacoba Sandra, Kuntsi, Jonna, Larsson, Henrik, Li, Tingyu, Liu, Jing, Merzon, Eugene, Mattingly, Gregory, Mattos, Paulo, McCarthy, Suzanne, Mikami, Amori Yee, Molina, Brooke S.G., Nigg, Joel T., Purper-Ouakil, Diane, Omigbodun, Olayinka O., Polanczyk, Guilherme V., Pollak, Yehuda, Poulton, Alison S., Reif, Andreas, Rajkumar, Ravi Philip, Rubia, Katya, Reding, Andrew, Rucklidge, Julia, Romanos, Marcel, Ramos-Quiroga, J. Antoni, Schellekens, Arnt, Scheres, Anouk, Schoeman, Renata, Schweitzer, Julie B., Shah, Henal, Solanto, Mary V., Sonuga-Barke, Edmund, Soutullo, César, Steinhausen, Hans-Christoph, Swanson, James M., Thapar, Anita, Tripp, Gail, Glind, Geurt van de, Brink, Wim van den, Oord, Saskia van der, Venter, Andre, Vitiello, Benedetto, Walitza, Susanne, and Wang, Yufeng

Abstract

Background: Misconceptions about ADHD stigmatize affected people, reduce credibility of providers, and prevent/delay treatment. To challenge misconceptions, we curated findings with strong evidence base. Methods: We reviewed studies with more than 2000 participants or meta-analyses from five or more studies or 2000 or more participants. We excluded meta-analyses that did not assess publication bias, except for meta-analyses of prevalence. For network meta-analyses we required comparison adjusted funnel plots. We excluded treatment studies with waiting-list or treatment as usual controls. From this literature, we extracted evidence-based assertions about the disorder. Results: We generated 208 empirically supported statements about ADHD. The status of the included statements as empirically supported is approved by 80 authors from 27 countries and 6 continents. The contents of the manuscript are endorsed by 366 people who have read this document and agree with its contents. Conclusions: Many findings in ADHD are supported by meta-analysis. These allow for firm statements about the nature, course, outcome causes, and treatments for disorders that are useful for reducing misconceptions and stigma.

Published
2021

163. The World Federation of ADHD International Consensus Statement: 208 Evidence-based Conclusions about the Disorder

Author

Faraone, Stephen V; https://orcid.org/0000-0002-9217-3982, Banaschewski, Tobias; https://orcid.org/0000-0003-4595-1144, Coghill, David, Zheng, Yi, Biederman, Joseph, Bellgrove, Mark A, Newcorn, Jeffrey H, Gignac, Martin, Al Saud, Nouf M, Manor, Iris, Rohde, Luis Augusto, Yang, Li, Cortese, Samuele, Almagor, Doron, Stein, Mark A, Albatti, Turki H, Aljoudi, Haya F, Alqahtani, Mohammed M J, Asherson, Philip, Atwoli, Lukoye, Bölte, Sven, Buitelaar, Jan K, Crunelle, Cleo L, Daley, David, Dalsgaard, Søren, Döpfner, Manfred; https://orcid.org/0000-0002-7929-0463, Espinet, Stacey, Fitzgerald, Michael, Franke, Barbara, Haavik, Jan, Steinhausen, Hans-Christoph, Walitza, Susanne; https://orcid.org/0000-0002-8161-8683, et al, Faraone, Stephen V; https://orcid.org/0000-0002-9217-3982, Banaschewski, Tobias; https://orcid.org/0000-0003-4595-1144, Coghill, David, Zheng, Yi, Biederman, Joseph, Bellgrove, Mark A, Newcorn, Jeffrey H, Gignac, Martin, Al Saud, Nouf M, Manor, Iris, Rohde, Luis Augusto, Yang, Li, Cortese, Samuele, Almagor, Doron, Stein, Mark A, Albatti, Turki H, Aljoudi, Haya F, Alqahtani, Mohammed M J, Asherson, Philip, Atwoli, Lukoye, Bölte, Sven, Buitelaar, Jan K, Crunelle, Cleo L, Daley, David, Dalsgaard, Søren, Döpfner, Manfred; https://orcid.org/0000-0002-7929-0463, Espinet, Stacey, Fitzgerald, Michael, Franke, Barbara, Haavik, Jan, Steinhausen, Hans-Christoph, Walitza, Susanne; https://orcid.org/0000-0002-8161-8683, and et al

Abstract

BACKGROUND: Misconceptions about ADHD stigmatize affected people, reduce credibility of providers, and prevent/delay treatment. To challenge misconceptions, we curated findings with strong evidence base. METHODS: We reviewed studies with more than 2,000 participants or meta-analyses from five or more studies or 2,000 or more participants. We excluded meta-analyses that did not assess publication bias, except for meta-analyses of prevalence. For network meta-analyses we required comparison adjusted funnel plots. We excluded treatment studies with waiting-list or treatment as usual controls. From this literature, we extracted evidence-based assertions about the disorder. RESULTS: We generated 208 empirically supported statements about ADHD. The status of the included statements as empirically supported is approved by 79 authors from 27 countries and 6 continents. The contents of the manuscript are endorsed by 362 people who have read this document and agree with its contents. CONCLUSIONS: Many findings in ADHD are supported by meta-analysis. These allow for firm statements about the nature, course, outcome causes, and treatments for disorders that are useful for reducing misconceptions and stigma.

Published
2021

164. Virtual Histology of Cortical Thickness and Shared Neurobiology in 6 Psychiatric Disorders

Author

Onderzoeksgroep 2, Brain, Onderzoek Bob Oranje, Patel, Yash, Parker, Nadine, Shin, Jean, Howard, Derek, French, Leon, Thomopoulos, Sophia I., Pozzi, Elena, Abe, Yoshinari, Abé, Christoph, Anticevic, Alan, Alda, Martin, Aleman, Andre, Alloza, Clara, Alonso-Lana, Silvia, Ameis, Stephanie H., Anagnostou, Evdokia, McIntosh, Andrew A., Arango, Celso, Arnold, Paul D., Asherson, Philip, Assogna, Francesca, Auzias, Guillaume, Ayesa-Arriola, Rosa, Bakker, Geor, Banaj, Nerisa, Banaschewski, Tobias, Bandeira, Cibele E., Baranov, Alexandr, Bargalló, Núria, Bau, Claiton H.D., Baumeister, Sarah, Baune, Bernhard T., Bellgrove, Mark A., Benedetti, Francesco, Bertolino, Alessandro, Boedhoe, Premika S.W., Boks, Marco, Bollettini, Irene, Del Mar Bonnin, Caterina, Borgers, Tiana, Borgwardt, Stefan, Brandeis, Daniel, Brennan, Brian P., Bruggemann, Jason M., Janssen, Joost, Murphy, Declan, Ophoff, Roel A., Oranje, Bob, Shook, Devon, Van Haren, Neeltje E.M., Onderzoeksgroep 2, Brain, Onderzoek Bob Oranje, Patel, Yash, Parker, Nadine, Shin, Jean, Howard, Derek, French, Leon, Thomopoulos, Sophia I., Pozzi, Elena, Abe, Yoshinari, Abé, Christoph, Anticevic, Alan, Alda, Martin, Aleman, Andre, Alloza, Clara, Alonso-Lana, Silvia, Ameis, Stephanie H., Anagnostou, Evdokia, McIntosh, Andrew A., Arango, Celso, Arnold, Paul D., Asherson, Philip, Assogna, Francesca, Auzias, Guillaume, Ayesa-Arriola, Rosa, Bakker, Geor, Banaj, Nerisa, Banaschewski, Tobias, Bandeira, Cibele E., Baranov, Alexandr, Bargalló, Núria, Bau, Claiton H.D., Baumeister, Sarah, Baune, Bernhard T., Bellgrove, Mark A., Benedetti, Francesco, Bertolino, Alessandro, Boedhoe, Premika S.W., Boks, Marco, Bollettini, Irene, Del Mar Bonnin, Caterina, Borgers, Tiana, Borgwardt, Stefan, Brandeis, Daniel, Brennan, Brian P., Bruggemann, Jason M., Janssen, Joost, Murphy, Declan, Ophoff, Roel A., Oranje, Bob, Shook, Devon, and Van Haren, Neeltje E.M.

Published
2021

168. Dopaminergic haplotype as a predictor of spatial inattention in children with attention-deficit/hyperactivity disorder

Author

Bellgrove, Mark A., Johnson, Katherine A., Barry, Edwina, Mulligan, Aisling, Hawi, Ziarah, Gill, Michael, Robertson, Ian, and Chambers, Christopher D.

Subjects
Attention-deficit hyperactivity disorder -- Diagnosis, Attention-deficit hyperactivity disorder -- Research, Attention-deficit hyperactivity disorder -- Genetic aspects, Haplotypes -- Usage, Haplotypes -- Physiological aspects, Health, Psychology and mental health
Published
2009

169. Two types of action error: electrophysiological evidence for separable inhibitory and sustained attention neural mechanisms producing error on go/no-go tasks

Author

O'Connell, Redmond G., Dockree, Paul M., Bellgrove, Mark A., Turin, Alessandra, Ward, Seamus, Foxe, John J., and Robertson, Ian H.

Subjects
Evoked potentials (Electrophysiology) -- Research, Neural networks -- Physiological aspects, Neural networks -- Research, Neural network, Health, Psychology and mental health
Published
2009

175. sj-pdf-1-jad-10.1177_1087054720978549 – Supplemental material for Physical Health, Media Use, and Mental Health in Children and Adolescents With ADHD During the COVID-19 Pandemic in Australia

Author

Sciberras, Emma, Patel, Pooja, Stokes, Mark A., Coghill, David, Middeldorp, Christel M., Bellgrove, Mark A., Becker, Stephen P., Efron, Daryl, Stringaris, Argyris, Faraone, Stephen V., Bellows, Susannah T., Quach, Jon, Banaschewski, Tobias, McGillivray, Jane, Delyse Hutchinson, Silk, Tim J., Melvin, Glenn, Wood, Amanda G., Jackson, Anna, Loram, George, Engel, Lidia, Montgomery, Alicia, and Westrupp, Elizabeth

Subjects
FOS: Psychology, 170199 Psychology not elsewhere classified, Education
Abstract

Supplemental material, sj-pdf-1-jad-10.1177_1087054720978549 for Physical Health, Media Use, and Mental Health in Children and Adolescents With ADHD During the COVID-19 Pandemic in Australia by Emma Sciberras, Pooja Patel, Mark A. Stokes, David Coghill, Christel M. Middeldorp, Mark A. Bellgrove, Stephen P. Becker, Daryl Efron, Argyris Stringaris, Stephen V. Faraone, Susannah T. Bellows, Jon Quach, Tobias Banaschewski, Jane McGillivray, Delyse Hutchinson, Tim J. Silk, Glenn Melvin, Amanda G. Wood, Anna Jackson, George Loram, Lidia Engel, Alicia Montgomery and Elizabeth Westrupp in Journal of Attention Disorders

Published
2020
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178. Physical Health, Media Use, and Mental Health in Children and Adolescents With ADHD During the COVID-19 Pandemic in Australia

Author

Sciberras, Emma, Patel, Pooja, Stokes, Mark A, Coghill, David, Middeldorp, Christel M, Bellgrove, Mark A, Becker, Stephen P, Efron, Daryl, Stringaris, Argyris, Faraone, Stephen V, Bellows, Susannah T, Quach, Jon, Banaschewski, Tobias, McGillivray, Jane, Hutchinson, Delyse, Silk, Tim J, Melvin, Glenn, Wood, Amanda G, Jackson, Anna, Loram, George, Engel, Lidia, Montgomery, Alicia, Westrupp, Elizabeth, Sciberras, Emma, Patel, Pooja, Stokes, Mark A, Coghill, David, Middeldorp, Christel M, Bellgrove, Mark A, Becker, Stephen P, Efron, Daryl, Stringaris, Argyris, Faraone, Stephen V, Bellows, Susannah T, Quach, Jon, Banaschewski, Tobias, McGillivray, Jane, Hutchinson, Delyse, Silk, Tim J, Melvin, Glenn, Wood, Amanda G, Jackson, Anna, Loram, George, Engel, Lidia, Montgomery, Alicia, and Westrupp, Elizabeth

Abstract

Objective: To examine the impact of COVID-19 restrictions among children with attention-deficit/hyperactivity disorder (ADHD). Methods: Parents of 213 Australian children (5–17 years) with ADHD completed a survey in May 2020 when COVID-19 restrictions were in place (i.e., requiring citizens to stay at home except for essential reasons). Results: Compared to pre-pandemic, children had less exercise (Odds Ratio (OR) = 0.4; 95% CI 0.3–0.6), less outdoor time (OR = 0.4; 95% 0.3–0.6), and less enjoyment in activities (OR = 6.5; 95% CI 4.0–10.4), while television (OR = 4.0; 95% CI 2.5–6.5), social media (OR = 2.4; 95% CI 1.3–4.5), gaming (OR = 2.0; 95% CI 1.3–3.0), sad/depressed mood (OR = 1.8; 95% CI 1.2–2.8), and loneliness (OR = 3.6; 95% CI 2.3–5.5) were increased. Child stress about COVID-19 restrictions was associated with poorer functioning across most domains. Most parents (64%) reported positive changes for their child including more family time. Conclusions: COVID-19 restrictions were associated with both negative and positive impacts among children with ADHD.

Published
2020

179. Consortium neuroscience of attention deficit/hyperactivity disorder and autism spectrum disorder: The ENIGMA adventure

Author

Hoogman, Martine, van Rooij, Daan, Klein, Marieke, Boedhoe, Premika, Ilioska, Iva, Li, Ting, Patel, Yash, Postema, Merel C, Zhang-James, Yanli, Anagnostou, Evdokia, Arango, Celso, Auzias, Guillaume, Banaschewski, Tobias, Bau, Claiton HD, Behrmann, Marlene, Bellgrove, Mark A, Brandeis, Daniel, Brem, Silvia, Busatto, Geraldo F, Calderoni, Sara, Calvo, Rosa, Castellanos, Francisco X, Coghill, David, Conzelmann, Annette, Daly, Eileen, Deruelle, Christine, Dinstein, Ilan, Durston, Sarah, Ecker, Christine, Ehrlich, Stefan, Epstein, Jeffery N, Fair, Damien A, Fitzgerald, Jacqueline, Freitag, Christine M, Frodl, Thomas, Gallagher, Louise, Grevet, Eugenio H, Haavik, Jan, Hoekstra, Pieter J, Janssen, Joost, Karkashadze, Georgii, King, Joseph A, Konrad, Kerstin, Kuntsi, Jonna, Lazaro, Luisa, Lerch, Jason P, Lesch, Klaus-Peter, Louza, Mario R, Luna, Beatriz, Mattos, Paulo, McGrath, Jane, Muratori, Filippo, Murphy, Clodagh, Nigg, Joel T, Oberwelland-Weiss, Eileen, O'Gorman Tuura, Ruth L, O'Hearn, Kirsten, Oosterlaan, Jaap, Parellada, Mara, Pauli, Paul, Plessen, Kerstin J, Ramos-Quiroga, J Antoni, Reif, Andreas, Reneman, Liesbeth, Retico, Alessandra, Rosa, Pedro GP, Rubia, Katya, Shaw, Philip, Silk, Tim J, Tamm, Leanne, Vilarroya, Oscar, Walitza, Susanne, Jahanshad, Neda, Faraone, Stephen V, Francks, Clyde, van den Heuvel, Odile A, Paus, Tomas, Thompson, Paul M, Buitelaar, Jan K, Franke, Barbara, Hoogman, Martine, van Rooij, Daan, Klein, Marieke, Boedhoe, Premika, Ilioska, Iva, Li, Ting, Patel, Yash, Postema, Merel C, Zhang-James, Yanli, Anagnostou, Evdokia, Arango, Celso, Auzias, Guillaume, Banaschewski, Tobias, Bau, Claiton HD, Behrmann, Marlene, Bellgrove, Mark A, Brandeis, Daniel, Brem, Silvia, Busatto, Geraldo F, Calderoni, Sara, Calvo, Rosa, Castellanos, Francisco X, Coghill, David, Conzelmann, Annette, Daly, Eileen, Deruelle, Christine, Dinstein, Ilan, Durston, Sarah, Ecker, Christine, Ehrlich, Stefan, Epstein, Jeffery N, Fair, Damien A, Fitzgerald, Jacqueline, Freitag, Christine M, Frodl, Thomas, Gallagher, Louise, Grevet, Eugenio H, Haavik, Jan, Hoekstra, Pieter J, Janssen, Joost, Karkashadze, Georgii, King, Joseph A, Konrad, Kerstin, Kuntsi, Jonna, Lazaro, Luisa, Lerch, Jason P, Lesch, Klaus-Peter, Louza, Mario R, Luna, Beatriz, Mattos, Paulo, McGrath, Jane, Muratori, Filippo, Murphy, Clodagh, Nigg, Joel T, Oberwelland-Weiss, Eileen, O'Gorman Tuura, Ruth L, O'Hearn, Kirsten, Oosterlaan, Jaap, Parellada, Mara, Pauli, Paul, Plessen, Kerstin J, Ramos-Quiroga, J Antoni, Reif, Andreas, Reneman, Liesbeth, Retico, Alessandra, Rosa, Pedro GP, Rubia, Katya, Shaw, Philip, Silk, Tim J, Tamm, Leanne, Vilarroya, Oscar, Walitza, Susanne, Jahanshad, Neda, Faraone, Stephen V, Francks, Clyde, van den Heuvel, Odile A, Paus, Tomas, Thompson, Paul M, Buitelaar, Jan K, and Franke, Barbara

Published
2020

180. Consortium neuroscience of attention deficit/hyperactivity disorder and autism spectrum disorder : The adventure

Author

Hoogman, Martine, van Rooij, Daan, Klein, Marieke, Boedhoe, Premika, Ilioska, Iva, Li, Ting, Patel, Yash, Postema, Merel C., Zhang-James, Yanli, Anagnostou, Evdokia, Arango, Celso, Auzias, Guillaume, Banaschewski, Tobias, Bau, Claiton H. D., Behrmann, Marlene, Bellgrove, Mark A., Brandeis, Daniel, Brem, Silvia, Busatto, Geraldo F., Calderoni, Sara, Calvo, Rosa, Castellanos, Francisco X., Coghill, David, Conzelmann, Annette, Daly, Eileen, Deruelle, Christine, Dinstein, Ilan, Durston, Sarah, Ecker, Christine, Ehrlich, Stefan, Epstein, Jeffery N., Fair, Damien A., Fitzgerald, Jacqueline, Freitag, Christine M., Frodl, Thomas, Gallagher, Louise, Grevet, Eugenio H., Haavik, Jan, Hoekstra, Pieter J., Janssen, Joost, Karkashadze, Georgii, King, Joseph A., Konrad, Kerstin, Kuntsi, Jonna, Lazaro, Luisa, Lerch, Jason P., Lesch, Klaus-Peter, Louza, Mario R., Luna, Beatriz, Mattos, Paulo, McGrath, Jane, Muratori, Filippo, Murphy, Clodagh, Nigg, Joel T., Oberwelland-Weiss, Eileen, O'Gorman Tuura, Ruth L., O'Hearn, Kirsten, Oosterlaan, Jaap, Parellada, Mara, Pauli, Paul, Plessen, Kerstin J., Ramos-Quiroga, Josep Antoni, Reif, Andreas, Reneman, Liesbeth, Retico, Alessandra, Rosa, Pedro G. P., Rubia, Katya, Shaw, Philip, Silk, Tim J., Tamm, Leanne, Vilarroya, Oscar, Walitza, Susanne, Jahanshad, Neda, Faraone, Stephen V., Francks, Clyde, van den Heuvel, Odile A., Paus, Tomas, Thompson, Paul M., Buitelaar, Jan K., Franke, Barbara, Hoogman, Martine, van Rooij, Daan, Klein, Marieke, Boedhoe, Premika, Ilioska, Iva, Li, Ting, Patel, Yash, Postema, Merel C., Zhang-James, Yanli, Anagnostou, Evdokia, Arango, Celso, Auzias, Guillaume, Banaschewski, Tobias, Bau, Claiton H. D., Behrmann, Marlene, Bellgrove, Mark A., Brandeis, Daniel, Brem, Silvia, Busatto, Geraldo F., Calderoni, Sara, Calvo, Rosa, Castellanos, Francisco X., Coghill, David, Conzelmann, Annette, Daly, Eileen, Deruelle, Christine, Dinstein, Ilan, Durston, Sarah, Ecker, Christine, Ehrlich, Stefan, Epstein, Jeffery N., Fair, Damien A., Fitzgerald, Jacqueline, Freitag, Christine M., Frodl, Thomas, Gallagher, Louise, Grevet, Eugenio H., Haavik, Jan, Hoekstra, Pieter J., Janssen, Joost, Karkashadze, Georgii, King, Joseph A., Konrad, Kerstin, Kuntsi, Jonna, Lazaro, Luisa, Lerch, Jason P., Lesch, Klaus-Peter, Louza, Mario R., Luna, Beatriz, Mattos, Paulo, McGrath, Jane, Muratori, Filippo, Murphy, Clodagh, Nigg, Joel T., Oberwelland-Weiss, Eileen, O'Gorman Tuura, Ruth L., O'Hearn, Kirsten, Oosterlaan, Jaap, Parellada, Mara, Pauli, Paul, Plessen, Kerstin J., Ramos-Quiroga, Josep Antoni, Reif, Andreas, Reneman, Liesbeth, Retico, Alessandra, Rosa, Pedro G. P., Rubia, Katya, Shaw, Philip, Silk, Tim J., Tamm, Leanne, Vilarroya, Oscar, Walitza, Susanne, Jahanshad, Neda, Faraone, Stephen V., Francks, Clyde, van den Heuvel, Odile A., Paus, Tomas, Thompson, Paul M., Buitelaar, Jan K., and Franke, Barbara

Abstract

Neuroimaging has been extensively used to study brain structure and function in individuals with attention deficit/hyperactivity disorder (ADHD) and autism spectrum disorder (ASD) over the past decades. Two of the main shortcomings of the neuroimaging literature of these disorders are the small sample sizes employed and the heterogeneity of methods used. In 2013 and 2014, the ENIGMA-ADHD and ENIGMA-ASD working groups were respectively, founded with a common goal to address these limitations. Here, we provide a narrative review of the thus far completed and still ongoing projects of these working groups. Due to an implicitly hierarchical psychiatric diagnostic classification system, the fields of ADHD and ASD have developed largely in isolation, despite the considerable overlap in the occurrence of the disorders. The collaboration between the ENIGMA-ADHD and -ASD working groups seeks to bring the neuroimaging efforts of the two disorders closer together. The outcomes of case-control studies of subcortical and cortical structures showed that subcortical volumes are similarly affected in ASD and ADHD, albeit with small effect sizes. Cortical analyses identified unique differences in each disorder, but also considerable overlap between the two, specifically in cortical thickness. Ongoing work is examining alternative research questions, such as brain laterality, prediction of case-control status, and anatomical heterogeneity. In brief, great strides have been made toward fulfilling the aims of the ENIGMA collaborations, while new ideas and follow-up analyses continue that include more imaging modalities (diffusion MRI and resting-state functional MRI), collaborations with other large databases, and samples with dual diagnoses

Published
2020

184. Executive 'brake failure' following deactivation of human frontal lobe

Author

Chambers, Christopher D., Bellgrove, Mark A., Stokes, Mark G., Henderson, Tracy R., Garavan, Hugh, Robertson, Ian H., Morris, Adam P., and Mattingley, Jason B.

Subjects
Frontal lobes -- Analysis, Response consistency -- Research, Traffic accidents -- Physiological aspects, Traffic accidents -- Reports, Health, Psychology and mental health
Published
2006

185. The Monash Autism-ADHD Genetics and Neurodevelopment (MAGNET) Project Design and Methodologies: A dimensional approach to understanding neurobiological and genetic aetiology.

Author

Knott, Rachael, primary, Johnson, Beth P, additional, Tiego, Jeggan, additional, Mellahn, Olivia, additional, Finlay, Amy, additional, Kallady, Kathryn, additional, Kouspous, Maria, additional, Sindhu, Vishnu Priya Mohankuma, additional, Hawi, Ziarih, additional, Arnatkeviciute, Aurina, additional, Chau, Tracey, additional, Maron, Dalia, additional, Mercieca, Emily-Clare, additional, Furley, Kirsten, additional, Harris, Katrina, additional, Williams, Katrina, additional, Ure, Alexandra, additional, Fornito, Alex, additional, Gray, Kylie, additional, Coghill, David, additional, Nicholson, Ann, additional, Phuong, Dinh, additional, Loth, Eva, additional, Mason, Luke, additional, Murphy, Declan, additional, Buitelaar, Jan, additional, and Bellgrove, Mark A., additional

Published
2021
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188. Physical Health, Media Use, and Mental Health in Children and Adolescents With ADHD During the COVID-19 Pandemic in Australia

Author

Sciberras, Emma, primary, Patel, Pooja, additional, Stokes, Mark A., additional, Coghill, David, additional, Middeldorp, Christel M., additional, Bellgrove, Mark A., additional, Becker, Stephen P., additional, Efron, Daryl, additional, Stringaris, Argyris, additional, Faraone, Stephen V., additional, Bellows, Susannah T., additional, Quach, Jon, additional, Banaschewski, Tobias, additional, McGillivray, Jane, additional, Hutchinson, Delyse, additional, Silk, Tim J., additional, Melvin, Glenn, additional, Wood, Amanda G., additional, Jackson, Anna, additional, Loram, George, additional, Engel, Lidia, additional, Montgomery, Alicia, additional, and Westrupp, Elizabeth, additional

Published
2020
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189. International Consensus on Standard Outcome Measures for Neurodevelopmental Disorders: A Consensus Statement.

Author

Mulraney, Melissa, de Silva, Umanga, Joseph, Andria, Sousa Fialho, Maria da Luz, Dutia, Iain, Munro, Natalie, Payne, Jonathan M., Banaschewski, Tobias, de Lima, Cláudia Bandeira, Bellgrove, Mark A., Chamberlain, Samuel R., Chan, Phyllis, Chong, Ivy, Clink, Alison, Cortese, Samuele, Daly, Eileen, Faraone, Stephen V., Gladstone, Melissa, Guastella, Adam J., and Järvdike, Juulia

Published
2024
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190. An Australian Cross-Sectional Survey of Parents' Experiences of Emergency Department Visits Among Children with Autism Spectrum Disorder.

Author

Garrick, Alice, Lee, Marie L., Scarffe, Carrington, Attwood, Tony, Furley, Kirsten, Bellgrove, Mark A., and Johnson, Beth P.

Subjects
AUTISM, PARENT attitudes, MEDICAL quality control, HOSPITAL emergency services, PARENTS of children with disabilities, SELF-management (Psychology), CHILD behavior, EXPERIENCE, BEHAVIOR disorders, PSYCHOSOCIAL factors, QUESTIONNAIRES, MEDICAL appointments, COMORBIDITY, CHILDREN
Abstract

Parents of children with ASD who had attended an Australian emergency department (ED; n = 421) completed a questionnaire relating to their experiences in the ED, including (1) child's reason for presentation and existing comorbidities, (2) quality of care during the visit (3) child's behaviour during visit, e.g. sensory responses to the ED environment, and disruptive behaviours. Children with comorbid ASD and intellectual disability were more likely to present with gastrointestinal issues and seizures, while those with comorbid ASD and oppositional defiant disorder were more likely to present with self-injury. ED staff awareness of ASD-related issues, including communication and expression of pain, were common difficulties for parents. The ED environment (e.g. lights, sounds, waiting areas), exacerbated child anxiety and led to disruptive behaviour. [ABSTRACT FROM AUTHOR]

Published
2022
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191. Dopamine influences attentional rate modulation in Macaque posterior parietal cortex.

Author

van Kempen, Jochem, Brandt, Christian, Distler, Claudia, Bellgrove, Mark A., and Thiele, Alexander

Subjects
PARIETAL lobe, MACAQUES, DOPAMINE, RHESUS monkeys, MONOTONIC functions, COGNITIVE neuroscience, NEUROPHARMACOLOGY, DOPAMINE receptors
Abstract

Cognitive neuroscience has made great strides in understanding the neural substrates of attention, but our understanding of its neuropharmacology remains incomplete. Although dopamine has historically been studied in relation to frontal functioning, emerging evidence suggests important dopaminergic influences in parietal cortex. We recorded single- and multi-unit activity whilst iontophoretically administering dopaminergic agonists and antagonists while rhesus macaques performed a spatial attention task. Out of 88 units, 50 revealed activity modulation by drug administration. Dopamine inhibited firing rates according to an inverted-U shaped dose–response curve and increased gain variability. D1 receptor antagonists diminished firing rates according to a monotonic function and interacted with attention modulating gain variability. Finally, both drugs decreased the pupil light reflex. These data show that dopamine shapes neuronal responses and modulates aspects of attentional processing in parietal cortex. [ABSTRACT FROM AUTHOR]

Published
2022
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199. Genetic influences on hub connectivity of the human connectome

Author

Arnatkevičiūtė, Aurina, primary, Fulcher, Ben D., additional, Oldham, Stuart, additional, Tiego, Jeggan, additional, Paquola, Casey, additional, Gerring, Zachary, additional, Aquino, Kevin, additional, Hawi, Ziarih, additional, Johnson, Beth, additional, Ball, Gareth, additional, Klein, Marieke, additional, Deco, Gustavo, additional, Franke, Barbara, additional, Bellgrove, Mark, additional, and Fornito, Alex, additional

Published
2020
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200. Consortium neuroscience of attention deficit/hyperactivity disorder and autism spectrum disorder: The ENIGMA adventure

Author

Hoogman, Martine, primary, van Rooij, Daan, additional, Klein, Marieke, additional, Boedhoe, Premika, additional, Ilioska, Iva, additional, Li, Ting, additional, Patel, Yash, additional, Postema, Merel C., additional, Zhang‐James, Yanli, additional, Anagnostou, Evdokia, additional, Arango, Celso, additional, Auzias, Guillaume, additional, Banaschewski, Tobias, additional, Bau, Claiton H. D., additional, Behrmann, Marlene, additional, Bellgrove, Mark A., additional, Brandeis, Daniel, additional, Brem, Silvia, additional, Busatto, Geraldo F., additional, Calderoni, Sara, additional, Calvo, Rosa, additional, Castellanos, Francisco X., additional, Coghill, David, additional, Conzelmann, Annette, additional, Daly, Eileen, additional, Deruelle, Christine, additional, Dinstein, Ilan, additional, Durston, Sarah, additional, Ecker, Christine, additional, Ehrlich, Stefan, additional, Epstein, Jeffery N., additional, Fair, Damien A., additional, Fitzgerald, Jacqueline, additional, Freitag, Christine M., additional, Frodl, Thomas, additional, Gallagher, Louise, additional, Grevet, Eugenio H., additional, Haavik, Jan, additional, Hoekstra, Pieter J., additional, Janssen, Joost, additional, Karkashadze, Georgii, additional, King, Joseph A., additional, Konrad, Kerstin, additional, Kuntsi, Jonna, additional, Lazaro, Luisa, additional, Lerch, Jason P., additional, Lesch, Klaus‐Peter, additional, Louza, Mario R., additional, Luna, Beatriz, additional, Mattos, Paulo, additional, McGrath, Jane, additional, Muratori, Filippo, additional, Murphy, Clodagh, additional, Nigg, Joel T., additional, Oberwelland‐Weiss, Eileen, additional, O'Gorman Tuura, Ruth L., additional, O'Hearn, Kirsten, additional, Oosterlaan, Jaap, additional, Parellada, Mara, additional, Pauli, Paul, additional, Plessen, Kerstin J., additional, Ramos‐Quiroga, J. Antoni, additional, Reif, Andreas, additional, Reneman, Liesbeth, additional, Retico, Alessandra, additional, Rosa, Pedro G. P., additional, Rubia, Katya, additional, Shaw, Philip, additional, Silk, Tim J., additional, Tamm, Leanne, additional, Vilarroya, Oscar, additional, Walitza, Susanne, additional, Jahanshad, Neda, additional, Faraone, Stephen V., additional, Francks, Clyde, additional, van den Heuvel, Odile A., additional, Paus, Tomas, additional, Thompson, Paul M., additional, Buitelaar, Jan K., additional, and Franke, Barbara, additional

Published
2020
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