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Copyright of Journal of Beijing Institute of Petrochemical Technology is the property of Journal of Beijing Institute of Petrochemical Technology Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Iron Steel Vanadium Titanium is the property of Iron Steel Vanadium Titanium Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Vibration, Measurement & Diagnosis is the property of Nanjing Hangkong Daxue and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Functional Materials / Gongneng Cailiao is the property of Chongqing Functional Materials Periodical Press and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Drainage & Irrigation Machinery Engineering / Paiguan Jixie Gongcheng Xuebao is the property of Editorial Department of Drainage & Irrigation Machinery Engineering and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Chinese Journal of Applied Mechanics is the property of Chinese Journal of Applied Mechanics Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Chinese Journal of Computational Mechanics / Jisuan Lixue Xuebao is the property of Chinese Journal of Computational Mechanics Editorial Office, Dalian University of Technology and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Food Safety & Quality is the property of Journal of Food Safety & Quality Editorial Department and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Acta Agriculturae Zhejiangensis is the property of Acta Agriculturae Zhejiangensis Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Acta Edulis Fungi is the property of Acta Edulis Fungi and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of China Pulp & Paper is the property of China Pulp & Paper Magazines Publisher and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Donghua University (Natural Science Edition) is the property of Journal of Donghua University (Natural Science) Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Donghua University (Natural Science Edition) is the property of Journal of Donghua University (Natural Science) Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of China Brewing is the property of China Brewing Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Engineering Mechanics / Gongcheng Lixue is the property of Engineering Mechanics Editorial Department and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Pharmaceutical Practice & Service is the property of Journal of Pharmaceutical Practice Editorial Department and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Nonferrous Metals (Extractive Metallurgy) is the property of Beijing Research Institute of Mining & Metallurgy Technology Group and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of the Chinese Society of Rare Earths is the property of Editorial Department of Journal of the Chinese Society of Rare Earths and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Electric Power Automation Equipment / Dianli Zidonghua Shebei is the property of Electric Power Automation Equipment Press and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Hubei Open Vocational College is the property of Journal of Hubei Open Vocational College Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of South China University of Technology (Natural Science Edition) is the property of South China University of Technology and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

BACKGROUND: Mesenchymal stem cell transplantation has a certain effect on spinal cord injury, but there are still some problems such as low survival rate and poor efficiency of cell transplantation caused by local oxidative stress environment. OBJECTIVE: To explore the protective effect of mangiferin on oxidative stress of bone marrow mesenchymal stem cells. METHODS: Rat bone marrow mesenchymal stem cells at passage 3 were added to mangiferin and incubated for 2 hours according to the gradient of concentration (0, 20, 40, 80, and 160 µmol/L). A serum-free medium containing 400 µmol/L H2O2 was added, and a gradient concentration of mangiferin was added again and cultured for 12 and 24 hours. Rat bone marrow mesenchymal stem cells were cultured as normal control group. Cell survival was detected by MTT assay in each group. The superoxide dismutase, malondialdehyde, and catalase in the culture medium were detected in accordance with the instruction of the kit. RESULTS AND CONCLUSION: Compared with normal control group, cell viability in the H2O2 group was significantly decreased (P < 0.01), and the levels of superoxide dismutase and catalase were significantly decreased (P < 0.01), while the level of malondialdehyde was significantly increased (P < 0.01). Compared with H2O2 group, the survival rate of cells was significantly increased (P < 0.01), and the levels of superoxide dismutase and catalase were significantly increased (P < 0.01), while the level of malondialdehyde was significantly decreased (P < 0.01) in the mangiferin group. Mangiferin showed concentration-dependent antioxidant stress protective activity above 20 µmol/L, and no cytotoxicity below 160 µmol/L. These findings indicate that antioxidant mangiferin can increase the antioxidant activity of bone marrow mesenchymal stem cells and provide a new preconditioning strategy for bone marrow mesenchymal stem cell transplantation. [ABSTRACT FROM AUTHOR]

Copyright of Chinese Journal of Tissue Engineering Research / Zhongguo Zuzhi Gongcheng Yanjiu is the property of Chinese Journal of Tissue Engineering Research and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

苍鹭（Ardea Cinerea Linnaeus）是属于鹳形目鹭科的常见涉禽,是典型的沼生鸟类。1985年至1986年,我们在牡丹江鹭岛对其进行了环志迁徙研究。我们共环志雏鸟100只（1985年环志87只1986年环志13只）除4只死亡外,其余全部迁离鹭岛。至1988年底,共回收脚环8只（其中4只在鹭岛回收。回收率达8%）。从回收信息得知,苍鹭越冬迁徙可远达海南省,迁徙路程达3000公里以上,为我国环志鸟类迁徙最远记录。为我国鸟类环志迁徙研究提供了重要数据。

In order to carry out emergency rescue for different disaster affected points more reasonably and efficiently, a model based on the combination weighting-technique for order preference by similarity to an ideal solution(TOPSIS) model was proposed and a hierarchical study on the urgency of rescue demand at disaster affected points was carried out. Firstly, based on analyzing the influencing factors of the urgency of rescue demand at disaster affected points, an evaluation index system for the urgency of rescue demand at disaster affected points was constructed. Secondly, the comprehensive weight of each index was obtained through criteria importance though intercrieria correlation (CRITIC) and entropy weight method. Then, the urgency of rescue demand at disaster affected points was quantitatively classified based on the combination weighting-TOPSIS method. Finally, a case study was conducted with the Wenchuan Earthquake as the object. The results show that the weights obtained from the combination weighting can get more objective and reasonable results than the single weighting, which is conducive to the emergency management department to carry out emergency rescue in a more timely, accurate, and orderly manner in the event of disasters. [ABSTRACT FROM AUTHOR]

Copyright of Feed Research is the property of Editorial Board of Feed Research and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Food Research & Development is the property of Food Research & Development Editorial Department and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Science & Technology of Food Industry is the property of Science & Technology of Food Industry Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Food & Fermentation Industries is the property of Food & Fermentation Industries and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Shipin Kexue/ Food Science is the property of Food Science Editorial Department and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Feed Industry is the property of Liaoning Provincial Institute of Agricultural Mechanization and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Yellow River is the property of Editorial Board of Yellow River and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

AIM: To investigate the impact of celastrol intervention on excitatory amino acid transporter 2 （EAAT2） and its neuroprotective role in subarachnoid hemorrhage （SAH）. METHODS: Western blot analysis was utilized to assess the EAAT2 expression level within 72 h after SAH, while glutamate concentration in cortical brain tissues was measured. Computational simulation was employed to explore the binding of celastrol with EAAT2. Seventy SD rats were randomly assigned to sham, model, model+GT949 （an EAAT2 agonist）, model+dihydrokainic acid （DHK; an EAAT2 inhibitor）, and model+celastrol groups. Glutamate concentration in cortical brain tissues was quantified, and brain edema was assessed by dry-wet weight method. Western blot analysis was conducted to evaluate the expression of EAAT2, aquaporin 4 and apoptosis-related proteins （Bax, Bcl-2, caspase-3 and caspase-9）, and TUNEL staining was employed to assess the apoptotic cell count in each group. RESULTS: （1） EAAT2 level decreased while glutamate concentration increased. （2） Celastrol was found to directly bind to EAAT2, enhancing EAAT2 expression and reducing glutamate concentration after SAH. （3） Celastrol demonstrated the ability to inhibit brain edema after SAH. （4） Celastrol was effective in reducing neuronal apoptosis after SAH. CONCLUSION: Celastrol has the potential to up-regulate EAAT2 expression, lower glutamate level, mitigate brain edema, and decrease neuronal apoptosis after SAH. [ABSTRACT FROM AUTHOR]

Objective: To investigate the effect of baicalin (BAI) on the proliferation and apoptosis of ovarian granulosa cells in polycystic ovary syndrome (PCOS) and its mechanisms. Methods: Forty-eight female SD rats were randomly divided into the control group, PCOS group, BAI low, middle and high dose groups and positive control group, with 8 rats in each group. PCOS model was established by subcutaneous injection of DHEA, and rats in the low, medium, and high dose groups of BAI were given baicalin (12.5, 25, and 50 mg/kg) by gavage. The Positive control group was given intraperitoneal injection (10 mg/kg) of Vitipofen; The control group and PCOS group were given equal volume 0.9% NaCl solution instead. Once a day for 4 weeks. The serum sex hormone levels were detected by enzyme-linked immunosorbant assay (ELISA). The pathological changes of ovary were observed by HE staining. After successful modeling, ovarian granulosa cells were extracted, and their proliferation was detected by MTT assay. Apoptosis was detected by Annex- inV-FITC/PI double staining and TUNEL staining. The relative expressions of BCL2 and BAX, P13K/AKT pathway related proteins P13K, AKT, p-P13K and p-AKT were detected by western blot. Results: The extracted ovarian granulosa cells are fibroblast-like and adhered well, with positive expression of specific proteins FSHR. Compared with the control group, the ovarian structure of rats in the PCOS group is disrupted, with an increase in bleeding, congestion, and the number of cystic follicles, as well as thickening of the white membrane. The levels of serum testosterone (T) and luteinizing hormone (LH), the apoptosis rate of ovarian granulosa cells and the expression of Bax protein are significantly increased (P<0.05), while the levels of Estradiolm (E2) and follicle stimulating hormone (FSH), the viability of ovarian granulosa cells, the expression of Bcl-2, p-P13K, and p-AKT protein are significantly decreased (P<0.05). Compared with PCOS group, BAI groups have obvious recovery of polycystic features, significant reduction in cysts, and complete arrangement of ovarian structure and granular cell layer. The levels of E2, and FSH in serum, the viability of ovarian granulosa cells, the expressions of Bcl-2, p-P13K and p-AKT protein are significantly increased in a dose-dependent manner (P<0.05), while the levels of T and LH in serum, the apoptosis rate of ovarian granulosa cells and the expression of Bax protein are significantly decreased in a dose-dependent manner (P<0.05). Conclusion: Baicalin may promote the proliferation and inhibit the apoptosis of ovarian granulosa cell, which may alleviate PCOS by activating the P13K/AKT signaling pathway. [ABSTRACT FROM AUTHOR]

Agricultural film residues which limit crop growth and cause soil pollution become increasingly serious. Exploring the effects of agricultural film residues with different amounts on the growth of maize and soil environment can provide theoretical support for the scientific and rational use of agricultural film. In this study, the distribution of residual film in maize farmland with film mulching in Hetao irrigation region of Inner Mongolia was taken as the research object, and 6 residual film gradients were set, including 0 (CK), 75kg·ha−1, 150kg·ha−1, 300kg·ha−1, 450kg·ha−1 and 600kg·ha−1, and the effects of different amounts of the agricultural film residues on maize yield and its components, root weight and taproot number, soil moisture content and bulk density were analyzed. The results showed that: (1) there was a negative correlation between the amount of film residues and the yield of maize, and there was a significant difference in the yield when the amount of film residues exceeded 300kg·ha−1 (P<0.05). With the increase of film residues, the bald tip of maize increased, and the 100-grain weight decreased significantly (P<0.05). (2) The increase of the film residues reduced the root quality and taproot numbers of maize, which were not conductive to the growth and development of the root system, and the ability of the root system to absorb water and nutrients from the soil decreased. (3) The film residues hindered the transport of soil water, soil water seeped slowly when the amount of film residues reached 300−450kg·ha−1, and the film residues over 600kg·ha−1 hindered the migration of soil capillary water and the infiltration of precipitation. Therefore, the use of scientific and reasonable ways to control soil residual film pollution control and recycle plastic film to reduce plastic film residues in the soil is helpful to promote the improvement of maize yield and soil quality, and realize the green and sustainable development of agriculture. [ABSTRACT FROM AUTHOR]

With the rise of Participatory Sensing technology, the scale and diversity of personal devices participating in data collection have continued to increase, leading to the emergence of a vast amount of multi dimensional numerical sensitive data, which has exacerbated the risk of privacy leakage. To address this issue, a personalized differential privacy protection scheme for multi dimensional numerical data from participatory sensing devices is proposed. This scheme achieves minimization of the mean squared error by designing a personalized privacy budget allocation scheme within a certain range and optimizing the sampling dimension of DPM (differential privacy mechanism). Based on this, PDPM (personalized dimensional partition mechanism) is designed to improve data availability and reduce the mean squared error after perturbation. Finally, experiments conducted on two real-world datasets verify that the proposed method significantly reduces the mean squared error of numerical data while protecting user privacy. Therefore, the proposed scheme provides a better balance between privacy protection and data availability. [ABSTRACT FROM AUTHOR]

The higher-order connectivity structure has been largely ignored, which contains a better signature of community compared with the lower-order connectivity structure, and the high-order information causes the inevitable fragmentation problem. To solve those problems,a motif-aware and graph Transformer(MGTrans) for community detection is proposed. Firstly, the maximal complete subgraph in the graph is searched and regarded as a motif, and the original graph is reconstructed with the motif as a unit to capture the motif adjacency matrix. At the same time, mixed-order outer-cut edges encoding is used to obtain the residual edge information of the original graph to solve the fragmentation problem, and position information and edge information on the reconstructed graph are captured through a position encoding matrix and motif short path with weight encoded. Then, the initial features are extracted by a graph transformer. Combing position encoding matrix, edge encoding matrix and initial features through the attention network to get motif embedding matrix for the community detection. Finally, The experimental results on several different datasets show the effectiveness of the MGTrans in improving the community detection performance of state-of-the-art methods and effectiveness for overlapping community detection and multi-community public node detection. [ABSTRACT FROM AUTHOR]

Multiple compression and impact of the air-assisted centralized seed metering device on rice seeds during high-speed sowing (≥12km/h) can easily lead to seed damage and adversely affects the emergence rate. This study aims to explore the damage of rice seeds under single and multiple mechanical compression in the air-assisted centralized seed metering device, according to the damage accumulation theory. The fitting equations of seed impact damage and compression were clarified to determine the matching range of stirring speed and the conveying airflow parameters during high-speed seeding. A systematic analysis was also implemented to explore where the seed was damaged under the repeated compression by the seed mixing device during high-speed seeding. The multiple impacts of airflow were evaluated during transportation and distribution in the air-assisted centralized seed metering device. The single compression test was carried out on the hybrid rice and conventional rice varieties. An elastic-plastic model was constructed suitable for rice seeds, in order to determine the critical value of elastic- plastic deformation. The multiple equal displacement compression tests were then carried out to determine the process of damage to rice seeds under multiple compressions. The critical deformation of rice seeds was determined and verified to combine with the seed germination rate test under multiple compressions. According to the conservation of energy, the critical speed was constructed at which the rice seeds were compressed and damaged by the stirring device. The fitting equation of impact damage and compression was combined to analyze the speed of seed airflow impact damage. The results showed that the crushing forces of conventional and hybrid rice seeds under single compression were (118.4±35.6) N and (113.2±39.9) N, respectively, the deformation during crushing was (0.59±0.07) mm and (0.63±0.11) mm, respectively, and the average critical deformation of elastic plasticity was 0.4 and 0.44 mm, respectively. In multiple compression tests, the maximum compression force of the seeds remained consistent, when the compression distance was less than the elastic-plastic average critical deformation; Once the compression distance was greater than the critical elastoplastic deformation, the maximum compressive force on the seed decreased gradually. Verification tests were also performed on the rice seeds germination rate. There was the a 0.44 mm critical deformation of hybrid rice seeds that caused damage. When the deformation of compressed seeds was less than 0.44 mm, there was no significant difference in the germination rate between compressed and uncompressed seeds after multiple compressions; When the compression deformation of the seeds was greater than 0.44 mm, the germination rate of rice seeds decreased after multiple cycles of compression. Therefore, the deformation of rice seeds after being loaded should be avoided to be greater than 0.44 mm. After that, the rotation speed range of the stirring device should be lower than 125 r/min and the seed transport speed should be lower than 8.5 m/s, in order to reduce the compression and impact damage of the air- assisted centralized seed metering device on rice seeds. This finding can provide a theoretical basis and parameter range to match the operating parameters during rice high-speed sowing. [ABSTRACT FROM AUTHOR]

Objective To explore the molecular mechanism of miR-212-3p in glioma cell proliferation,invasion and epithelial-mesenchymal transition (EMT). Methods The expression of miR-212-3p and NAP1L1were detected by RT-qPCR in glioma cells. NC mimic,miR-212-3p mimic,oe-NC and oe-NAP1L1 were built and transfected in cells. CCK-8, Transwell and wound healing assay were used to evaluate the cell biological behaviour. Western blot was used to detect the expression of EMT-related biomarkers. The relationship between miR-212-3p and NAP1L1 was confirmed by the dual-luciferase reporter gene and AgO2-RIP assay. Results miR-212-3p was lowly expressed in glioma cells (P< 0.000 1). miR-212-3p mimic significantly inhibited the glioma cell proliferation (P< 0.000 1), invasion (P = 0.001 1) and migration (P< 0.000 1), and reduced the expression of EMT-related biomarkers N-cadherin (P = 0.000 861) and Vimentin (P = 0.007 430), while upregulating the expression of E-cadherin (P< 0.000 1). miR-212-3p targeted and negatively regulated the NAP1L1 expression.Overexpression of NAP1L1 reversed the inhibitory effects of miR-212-3p on glioma cell proliferation (P< 0.000 1), migration (P< 0.000 1), and EMT (P< 0.000 1). Conclusion miR-212-3p inhibits the glioma cell proliferation, migration and EMT by targeting the negative regulation of NAP1L1 expression. [ABSTRACT FROM AUTHOR]

Copyright of Shandong Medical Journal is the property of Shandong Medical Health Newspapers and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)